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https://www.readbyqxmd.com/read/29451921/the-effectiveness-of-non-surgical-intervention-foot-orthoses-for-paediatric-flexible-pes-planus-a-systematic-review-update
#1
Sindhrani Dars, Hayley Uden, Helen A Banwell, Saravana Kumar
BACKGROUND: Flexible pes planus (flat feet) in children is a common presenting condition in clinical practice due to concerns amongst parents and caregivers. While Foot Orthoses (FOs) are a popular intervention, their effectiveness remains unclear. Thus, the aim of this systematic review was to update the current evidence base for the effectiveness of FOs for paediatric flexible pes planus. METHODS: A systematic search of electronic databases (Cochrane, Medline, AMED, EMBASE, CINHAL, SportDiscus, Scopus and PEDro) was conducted from January 2011 to July 2017...
2018: PloS One
https://www.readbyqxmd.com/read/29451557/biomedical-journal-speed-and-efficiency-a-cross-sectional-pilot-survey-of-author-experiences
#2
Joshua D Wallach, Alexander C Egilman, Anand D Gopal, Nishwant Swami, Harlan M Krumholz, Joseph S Ross
Background: Although the peer review process is believed to ensure scientific rigor, enhance research quality, and improve manuscript clarity, many investigators are concerned that the process is too slow, too expensive, too unreliable, and too static. In this feasibility study, we sought to survey corresponding authors of recently published clinical research studies on the speed and efficiency of the publication process. Methods: Web-based survey of corresponding authors of a 20% random sample of clinical research studies in MEDLINE-indexed journals with Ovid MEDLINE entry dates between December 1 and 15, 2016...
2018: Research Integrity and Peer Review
https://www.readbyqxmd.com/read/29451115/understanding-the-complexities-of-food-safety-using-a-one-health-approach
#3
Kalmia E Kniel, Deepak Kumar, Siddhartha Thakur
The philosophy of One Health is growing in concept and clarity. The interdependence of human, animal, and environmental health is the basis for the concept of One Health. One Health is a comprehensive approach to ensure the health of people, animals, and the environment through collaborative efforts. Preharvest food safety issues align with the grand concept of One Health. Imagine any food production system, and immediately, parallel images from One Health emerge: for example, transmission of zoonotic diseases, antibiotic residues, or resistance genes in the environment; environmental and animal host reservoirs of disease; challenges with rearing animals and growing fresh produce on the same farm; application and transport of manure or diseased animals...
February 2018: Microbiology Spectrum
https://www.readbyqxmd.com/read/29450971/evaluation-of-an-abutment-level-superpower-sound-processor-for-bone-anchored-hearing
#4
Arjan J Bosman, Ivo J Kruyt, Emmanuel Am Mylanus, Myrthe Ks Hol, Ad Fm Snik
OBJECTIVES: Performance of an abutment-level superpower sound processor for bone-anchored hearing, the Ponto 3 SuperPower from Oticon Medical (BCD2), was compared to an earlier model from Oticon Medical (BCD1). DESIGN: A comparative study in which each patient serves as its own control. SETTING: Tertiary clinic. PARTICIPANTS: Eighteen experienced BCD1 users with profound mixed hearing loss. MAIN OUTCOME MEASURES: speech reception thresholds in noise; APHAB and SSQ questionnaires...
February 16, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29450831/comparison-of-different-strategies-for-providing-fecal-microbiota-transplantation-to-treat-patients-with-recurrent-clostridium-difficile-infection-in-two-english-hospitals-a-review
#5
REVIEW
Simon D Goldenberg, Rahul Batra, Ian Beales, Jonathan Leith Digby-Bell, Peter Miles Irving, Lee Kellingray, Arjan Narbad, Ngozi Franslem-Elumogo
Fecal microbiota transplant (FMT) has emerged as a highly efficacious treatment for difficult cases of refractory and/or recurrent Clostridium difficile infection (CDI). There have been many well-conducted randomized controlled trials and thousands of patients reported in case series that describe success rates of approximately 90% following one or more FMT. Although the exact mechanisms of FMT have yet to be fully elucidated, replacement or restoration of a 'normal' microbiota (or at least a microbiota resembling those who have never had CDI) appears to have a positive effect on the gut dysbiosis that is thought to exist in these patients...
February 15, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29450493/the-impact-of-age-background-noise-semantic-ambiguity-and-hearing-loss-on-recognition-memory-for-spoken-sentences
#6
Margaret A Koeritzer, Chad S Rogers, Kristin J Van Engen, Jonathan E Peelle
Purpose: The goal of this study was to determine how background noise, linguistic properties of spoken sentences, and listener abilities (hearing sensitivity and verbal working memory) affect cognitive demand during auditory sentence comprehension. Method: We tested 30 young adults and 30 older adults. Participants heard lists of sentences in quiet and in 8-talker babble at signal-to-noise ratios of +15 dB and +5 dB, which increased acoustic challenge but left the speech largely intelligible...
February 15, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29450489/evaluating-readmission-need-for-more-clarity-on-methods-reply
#7
Ankur Gupta, Clyde W Yancy, Gregg C Fonarow
No abstract text is available yet for this article.
February 14, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29450464/evaluating-readmission-need-for-more-clarity-on-methods
#8
Harlan M Krumholz, Kumar Dharmarajan, Sharon-Lise T Normand
No abstract text is available yet for this article.
February 14, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29446439/vision-screening-for-correctable-visual-acuity-deficits-in-school-age-children-and-adolescents
#9
REVIEW
Jennifer R Evans, Priya Morjaria, Christine Powell
BACKGROUND: Although the benefits of vision screening seem intuitive, the value of such programmes in junior and senior schools has been questioned. In addition there exists a lack of clarity regarding the optimum age for screening and frequency at which to carry out screening. OBJECTIVES: To evaluate the effectiveness of vision screening programmes carried out in schools to reduce the prevalence of correctable visual acuity deficits due to refractive error in school-age children...
February 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29446033/climate-change-foodborne-pathogens-and-illness-in-higher-income-countries
#10
REVIEW
I R Lake, G C Barker
PURPOSE OF REVIEW: We present a review of the likely consequences of climate change for foodborne pathogens and associated human illness in higher-income countries. RECENT FINDINGS: The relationships between climate and food are complex and hence the impacts of climate change uncertain. This makes it difficult to know which foodborne pathogens will be most affected, what the specific effects will be, and on what timescales changes might occur. Hence, a focus upon current capacity and adaptation potential against foodborne pathogens is essential...
February 14, 2018: Current Environmental Health Reports
https://www.readbyqxmd.com/read/29445919/appraisal-of-clinical-practice-guidelines-on-the-management-of-hypothyroidism-in-pregnancy-using-the-appraisal-of-guidelines-for-research-and-evaluation-ii-instrument
#11
REVIEW
Yuan Fang, Liang Yao, Jing Sun, Jian Zhang, Yanxia Li, Ruifei Yang, Kehu Yang, Limin Tian
PURPOSE: This study aimed to systematically evaluate the quality of guidelines for the management of hypothyroidism in pregnancy. METHOD: Systematic searches were conducted to identify hypothyroidism in pregnancy guidelines published in electronic databases and developers' websites. Four reviewers independently evaluated eligible guidelines using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument. Agreement among reviewers was measured using the intraclass correlation coefficient (ICC)...
February 14, 2018: Endocrine
https://www.readbyqxmd.com/read/29444881/ischaemic-stroke-haemorrhage-and-mortality-in-older-patients-with-chronic-kidney-disease-newly-started-on-anticoagulation-for-atrial-fibrillation-a-population-based-study-from-uk-primary-care
#12
Shankar Kumar, Simon de Lusignan, Andrew McGovern, Ana Correa, Mariya Hriskova, Piers Gatenby, Simon Jones, David Goldsmith, A John Camm
OBJECTIVE: To assess the association between anticoagulation, ischaemic stroke, gastrointestinal and cerebral haemorrhage, and all cause mortality in older people with atrial fibrillation and chronic kidney disease. DESIGN: Propensity matched, population based, retrospective cohort analysis from January 2006 through December 2016. SETTING: The Royal College of General Practitioners Research and Surveillance Centre database population of almost 2...
February 14, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29444868/nhs-urgently-needs-clarity-on-eu-staff-rights-post-brexit-say-senior-doctors
#13
Abi Rimmer
No abstract text is available yet for this article.
February 14, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29444654/the-comparison-of-perceived-health-related-quality-of-life-between-australian-children-with-severe-specific-language-impairment-to-age-and-gender-matched-peers
#14
Kristy Nicola, Pauline Watter
BACKGROUND: Children with specific language impairment often present with multiple comorbidities, which may adversely affect both participation in play and academic performance, potentially impacting a child's health-related quality of life. This study 1) explored the suitability of the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales (PedsQL™) for use with a typically developing Australian control group, and 2) compared the health-related quality of life between a control group and Australian children with severe specific language impairment...
February 14, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29441182/pediatric-cardiac-anamnesis-prevention-of-additional-diagnostic-tests
#15
REVIEW
Izet Masic, Zijo Begic, Nabil Naser, Edin Begic
Pediatrics is defined as the science of a healthy and sick child from birth to end of adolescence. Diseases of the cardiovascular system are the leading causes of mortality in adults, with frequent onset in childhood. The cardiologic examination starts with anamnesis in a pleasant atmosphere, refined space, enough time and patience, detailed measurements, and preferably a noncrying child. Anamnesis, regardless of the development of diagnostic procedures, still constitutes the basis of every clinical examination...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29440160/interventions-to-increase-access-to-or-uptake-of-physical-health-screening-in-people-with-severe-mental-illness-a-realist-review
#16
Frédérique Lamontagne-Godwin, Caroline Burgess, Sarah Clement, Melanie Gasston-Hales, Carolynn Greene, Anne Manyande, Deborah Taylor, Paul Walters, Elizabeth Barley
OBJECTIVES: To identify and evaluate interventions aimed at increasing uptake of, or access to, physical health screening by adults with severe mental illness; to examine why interventions might work. DESIGN: Realist review. SETTING: Primary, secondary and tertiary care. RESULTS: A systematic search identified 1448 studies, of which 22 met the inclusion criteria. Studies were from Australia (n=3), Canada (n=1), Hong Kong (n=1), UK (n=11) and USA (n=6)...
February 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29439747/paediatric-obstructive-sleep-apnoea-can-our-identification-of-surgical-candidates-be-evidence-based
#17
L Pabla, J Duffin, L Flood, K Blackmore
BACKGROUND: Paediatric obstructive sleep apnoea is a common clinical condition managed by most ENT clinicians. However, despite the plethora of publications on the subject, there is wide variability, in the literature and in practice, on key aspects such as diagnostic criteria, the impact of co-morbidities and the indications for surgical correction. METHODS: A systematic review is presented, addressing four key questions from the available literature: (1) what is the evidence base for any definition of paediatric obstructive sleep apnoea?; (2) does it cause serious systemic illness?; (3) what co-morbidities influence the severity of paediatric obstructive sleep apnoea?; and (4) is there a medical answer? RESULTS AND CONCLUSION: There is a considerable lack of evidence regarding most of these fundamental questions...
February 14, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29439372/work-related-threats-and-violence-in-human-service-sectors-the-importance-of-the-psycho-social-work-environment-examined-in-a-multilevel-prospective-study
#18
Lars Peter Andersen, Annie Hogh, Karin Biering, Charlotte Ann Gadegaard
BACKGROUND: Threats and violence at work are major concerns for employees in many human service sectors. The prevention of work-related violence is a major challenge for employees and management. OBJECTIVE: The purpose of this study was to identify prospective associations between psycho-social work environment and work-related threats and violence in four high risk human service sectors. METHODS: Questionnaire data was collected from 3011 employees working at psychiatric wards, in the elder sector, in the Prison and Probation Service and at Special Schools...
2018: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29437550/a-simple-method-of-cataract-induction-in-adult-zebrafish
#19
Heather M Prior, Kerri Letwin, Amber Tuininga, Michelle Nguyen
We have developed a simple method for the induction of cataracts in adult zebrafish using hydrogen peroxide. Our method uses a corneal puncture followed by intraocular injection of hydrogen peroxide into the anterior chamber. The procedure can be done rapidly, forming a highly opaque cataract almost immediately, and fish recover quickly. The optical clarity of the lens is gradually regained over time, showing the innate ability of zebrafish to regenerate healthy lens tissue. This technique provides a simple in vivo system with which to assess mutant strains or targeted disruptions to genes expressed in the lens...
February 13, 2018: Zebrafish
https://www.readbyqxmd.com/read/29436112/cost-effectiveness-of-focal-impulse-and-rotor-modulation-guided-ablation-added-to-pulmonary-vein-isolation-for-atrial-fibrillation
#20
Tina Baykaner, Steve Duff, James T Hasegawa, Michael S Mafilios, Mintu P Turakhia
BACKGROUND: Although ablation with focal impulse and rotor modulation (FIRM), as an adjunct to pulmonary vein isolation (PVI), has been shown to decrease atrial fibrillation (AF) recurrence, cost-effectiveness has not been assessed. OBJECTIVE: We aimed to evaluate the cost effectiveness of FIRM-guided ablation when added to PVI in a mixed AF population. METHODS AND RESULTS: We used a Markov model to estimate the costs, quality-adjusted survival, and cost effectiveness of adding FIRM ablation to PVI...
February 13, 2018: Journal of Cardiovascular Electrophysiology
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