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https://www.readbyqxmd.com/read/28898571/risk-factors-of-post-ercp-pancreatitis-in-biliary-type-sphincter-of-oddi-dysfunction-in-japanese-patients
#1
Hiroyuki Miyatani, Satohiro Matsumoto, Hirosato Mashima
OBJECTIVES: Suspected sphincter of Oddi dysfunction (SOD) is a well-known risk factor for post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). The indication of ERCP for suspected SOD patients was very low in Japan compared to other countries. Therefore, the risk of PEP may be different in Japanese SOD patients. The objective of this study was to evaluate the risk of PEP in suspected biliary type SOD in Japan. METHODS: From December 1996 to January 2017, 72 patients were suspected to have biliary type SOD by questionnaire, liver function tests, hepatobiliary scintigraphy, abdominal ultrasonography, upper gastrointestinal endoscopy, endoscopic ultrasonography, and magnetic resonance cholangiopancreatography...
September 12, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28854319/slow-advancement-of-enteral-feed-volumes-to-prevent-necrotising-enterocolitis-in-very-low-birth-weight-infants
#2
REVIEW
Sam J Oddie, Lauren Young, William McGuire
BACKGROUND: Early enteral feeding practices are potentially modifiable risk factors for necrotising enterocolitis (NEC) in very preterm or very low birth weight (VLBW) infants. Observational studies suggest that conservative feeding regimens, including slowly advancing enteral feed volumes, reduce the risk of NEC. However, slow feed advancement may delay establishment of full enteral feeding and may be associated with metabolic and infectious morbidities secondary to prolonged exposure to parenteral nutrition...
August 30, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28853622/military-veteran-engagement-with-mental-health-and-well-being-services-a-qualitative-study-of-the-role-of-the-peer-support-worker
#3
Bronagh Weir, Margaret Cunningham, Lucy Abraham, Charlie Allanson-Oddy
BACKGROUND: Many UK military veterans experiencing mental health and well-being difficulties do not engage with support services to get the help they need. Some mental health clinics employ Peer Support Workers (PSWs) to help veteran patients engage, however it is not known how the role influences UK veteran engagement. AIMS: To gain insight into the role of peer support in UK veteran engagement with mental health and well-being services. METHOD: A qualitative study based on 18 semi-structured interviews with veterans, PSWs and mental health clinicians at a specialist veteran mental health and well-being clinic in Scotland...
August 30, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28817464/biologics-for-idiopathic-inflammatory-myopathies
#4
Siamak Moghadam-Kia, Rohit Aggarwal, Chester V Oddis
PURPOSE OF REVIEW: As treatment of refractory cases of idiopathic inflammatory myopathies (IIMs) has been challenging, there is growing interest in assessing novel biologics that target various pathways implicated in the pathogenesis of IIM. RECENT FINDINGS: In the largest clinical trial in adult and juvenile IIM assessing the effectiveness of rituximab, the primary outcome was not met but 83% of this refractory group of IIM patients met a predefined definition of improvement and rituximab demonstrated a significant glucocorticoid-sparing effect...
August 16, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28805087/preliminary-investigation-of-the-reliability-and-validity-of-the-birt-independent-living-scale
#5
Sara D S Ramos, Michael Oddy, Lorraine Haye, Anna Goodson
PURPOSE: Neurorehabilitation aims to increase independence and participation in ordinary life. It is argued that the fundamental indices of this are independent living and engagement in occupational or productive activity. The Brain Injury Rehabilitation Trust Independent Living Scale was designed to capture change in levels of participation and independence following neurorehabilitation. With greater use of outcome measures in health care, it becomes necessary to develop tools which are simple to use and that capture the holistic impact of rehabilitation...
August 13, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28802556/randomized-sham-controlled-trials-in-endoscopy-a-systematic-review-and-meta-analysis-of-adverse-events
#6
REVIEW
Allison R Schulman, Violeta Popov, Christopher C Thompson
BACKGROUND AND AIMS: Sham procedures in endoscopy are used with the intention of controlling for placebo response, potentially allowing more precise evaluation of treatment effect. Nevertheless, this type of study may impose significant risk without potential benefit for those in the sham group. The aim of the current study is to systematically review and analyze the endoscopic literature to assess the safety of sham controls. METHODS: MEDLINE and Embase databases were searched for endoscopic sham procedures for all dates through July 2017...
August 9, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28758369/early-life-factors-obesity-risk-and-the-metabolome-of-young-adults
#7
Sebastian Rauschert, Trevor A Mori, Lawrence J Beilin, Peter Jacoby, Olaf Uhl, Berthold Koletzko, Wendy H Oddy, Christian Hellmuth
OBJECTIVE: Noncommunicable diseases such as obesity have become a serious global public health epidemic. This study aimed to examine whether there was an association between early life factors (with a special focus on breastfeeding) BMI, waist circumference, and the metabolome in offspring at 20 years. METHODS: Data from the Western Australian Pregnancy Cohort (Raine) Study were analyzed using 1,024 plasma samples from the 20-year follow-up. A liquid chromatography, tandem mass spectrometry metabolomics approach was used to measure metabolites...
July 31, 2017: Obesity
https://www.readbyqxmd.com/read/28722168/role-of-palmitoylation-of-cysteine-415-in-functional-coupling-cb1-receptor-to-g%C3%AE-i2-protein
#8
Sergio Oddi, Antonio Totaro, Lucia Scipioni, Beatrice Dufrusine, Tomasz Maciej Stepniewski, Jana Selent, Mauro Maccarrone, Enrico Dainese
In this study, we investigated the role of CB1 palmitoylation in modulating the functional interaction with G proteins both in the absence and presence of agonist binding. Our data show that the nonpalmitoylated CB1 receptor significantly reduced its association with Gαi2 . The agonist stimulation induced a partial dissociation of Gαi2 proteins from the wild-type receptor, while on the C415A mutant the agonist binding was not able to induce a significant dissociation of Gαi2 from the receptor. The lack of palmitoyl chain seems to hamper the ability of the receptor to functionally interact with the Gαi2 and indicate that the palmitoyl chain is responsible for the functional transmission of the agonist-induced conformational change in the receptor of the G protein...
July 19, 2017: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/28711688/aga-institute-series-focus-on-enhancing-high-value-care-cost-effective-therapy-for-sphincter-of-oddi-dysfunction
#9
Dennis Yang, Patrick Yachimski
No abstract text is available yet for this article.
July 12, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28691687/pancreaticobiliary-maljunction-and-congenital-biliary-dilatation
#10
REVIEW
Terumi Kamisawa, Kenitiro Kaneko, Takao Itoi, Hisami Ando
Pancreaticobiliary maljunction is a congenital malformation in which the pancreatic and bile ducts join outside the duodenal wall, usually forming a long common channel. Because the action of the sphincter of Oddi does not regulate the function of the pancreaticobiliary junction in patients with pancreaticobiliary maljunction, two-way regurgitation occurs. Reflux of pancreatic juice into the biliary tract is associated with a high incidence of biliary cancer. Biliary carcinogenesis in patients with pancreaticobiliary maljunction is thought to follow the hyperplasia, dysplasia, then carcinoma sequence due to chronic inflammation caused by pancreatobiliary reflux...
August 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28659295/infant-feeding-and-growth-trajectory-patterns-in-childhood-and-body-composition-in-young-adulthood
#11
Peter Rzehak, Wendy H Oddy, M Luisa Mearin, Veit Grote, Trevor A Mori, Hania Szajewska, Raanan Shamir, Sibylle Koletzko, Martina Weber, Lawrence J Beilin, Rae-Chi Huang, Berthold Koletzko
Background: Growth patterns of breastfed and formula-fed infants may differ, with formula-fed infants growing more rapidly than breastfed infants into childhood and adulthood.Objective: Our objectives were to identify growth patterns and investigate early nutritional programming potential on growth patterns at 6 y and on body composition at 20 y.Design: The West Australian Pregnancy Cohort (Raine) Study and 3 European cohort studies (European Childhood Obesity Trial, Norwegian Human Milk Study, and Prevention of Coeliac Disease) that collaborate in the European Union-funded Early Nutrition project combined, harmonized, and pooled data on full breastfeeding, anthropometry, and body composition...
August 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28645989/joseph-a-oddis-honored-at-ashp-headquarters-dedication
#12
Kate Traynor
No abstract text is available yet for this article.
July 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28625150/update-on-the-molecular-mechanisms-underlying-the-effect-of-cholecystokinin-and-cholecystokinin-1-receptor-on-the-formation-of-cholesterol-gallstones
#13
Helen H Wang, Piero Portincasa, David Q-H Wang
Cholecystokinin (CCK) is an important neuro-intestinal peptide hormone produced by the enteroendocrine I-cells in the upper part of small intestine. Protein- and fat-enriched food plays an important role in triggering CCK secretion from the intestine. Carbohydrates stimulate only small amounts of CCK release. The CCK-1 receptor (CCK-1R) is largely localized in the gallbladder, sphincter of Oddi, pancreas, small intestine, gastric mucosa, and pyloric sphincter, where it is responsible for CCK to regulate multiple digestive processes including gallbladder contraction, pancreatic secretion, small intestinal transit, and gastric emptying...
June 19, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28622182/reflux-associated-cholecystopathy-analysis-of-76-gallbladders-from-patients-with-supra-oddi-union-of-the-pancreatic-duct-and-common-bile-duct-pancreatobiliary-maljunction-elucidates-a-specific-diagnostic-pattern-of-mucosal-hyperplasia-as-a-prelude-to-carcinoma
#14
Takashi Muraki, Bahar Memis, Michelle D Reid, Takeshi Uehara, Tetsuya Ito, Osamu Hasebe, Shinji Okaniwa, Naoto Horigome, Takeshi Hisa, Pardeep Mittal, Alexa Freedman, Shishir Maithel, Juan M Sarmiento, Alyssa Krasinskas, Jill Koshiol, Volkan Adsay
Pancreaticobiliary maljunction (PBM) is the anomalous union of the main pancreatic duct and common bile duct outside the Oddi-sphincter, allowing the reflux of pancreatic juice to the gallbladder. There is only limited awareness and understanding of the pathologic correlates of this condition, mostly from Japan; this entity is largely unrecognized in the West. In this study, 76 gallbladders from patients with PBM (64 from Japan; 12 from the United States) were analyzed and contrasted with 66 from non-PBM patients...
September 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28619255/infant-nutrition-and-maternal-obesity-influence-the-risk-of-non-alcoholic-fatty-liver-disease-in-adolescents
#15
Oyekoya T Ayonrinde, Wendy H Oddy, Leon A Adams, Trevor A Mori, Lawrence J Beilin, Nicholas de Klerk, John K Olynyk
BACKGROUND & AIMS: The pathway to non-alcoholic fatty liver disease (NAFLD) in adolescents may have its origins in adiposity gains, nutrition and sedentary lifestyle established during childhood. There is inadequate knowledge regarding the associations between infant nutrition and subsequent NAFLD. We examined the association of maternal factors and infant nutrition, with the subsequent diagnosis of NAFLD in adolescents. METHODS: Adolescents aged 17years in the Western Australian Pregnancy (Raine) Cohort study had fatty liver assessment using liver ultrasound...
May 22, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28607037/international-comparison-of-emergency-hospital-use-for-infants-data-linkage-cohort-study-in-canada-and-england
#16
Katie Harron, Ruth Gilbert, David Cromwell, Sam Oddie, Astrid Guttmann, Jan van der Meulen
OBJECTIVES: To compare emergency hospital use for infants in Ontario (Canada) and England. METHODS: We conducted a population-based data linkage study in infants born ≥34 weeks' gestation between 2010 and 2013 in Ontario (n=253 930) and England (n=1 361 128). Outcomes within 12 months of postnatal discharge were captured in hospital records. The primary outcome was all-cause unplanned admissions. Secondary outcomes included emergency department (ED) visits, any unplanned hospital contact (either ED or admission) and mortality...
June 12, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28592609/tracking-of-vitamin-d-status-from-childhood-to-early-adulthood-and-its-association-with-peak-bone-mass
#17
Kun Zhu, Wendy H Oddy, Patrick Holt, Wendy Chan She Ping-Delfos, Jenny Mountain, Stephen Lye, Craig Pennell, Prue H Hart, John P Walsh
Background: To our knowledge, there are few longitudinal studies of vitamin D status from childhood to early adulthood, and it is uncertain whether vitamin D predicts peak bone mass in young adults.Objectives: The purpose of this longitudinal study was to evaluate the long-term stability of vitamin D status from ages 6 to 20 y in healthy individuals and to study associations between serum 25-hydroxyvitamin D [25(OH)D] at different developmental stages and bone mass measured at age 20 y.Design: Participants were offspring of the Western Australian Pregnancy Cohort (Raine) study...
July 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28582656/non-linear-relationship-between-maternal-work-hours-and-child-body-weight-evidence-from-the-western-australian-pregnancy-cohort-raine-study
#18
Jianghong Li, Plamen Akaliyski, Jakob Schäfer, Garth Kendall, Wendy H Oddy, Fiona Stanley, Lyndall Strazdins
Using longitudinal data from the Western Australia Pregnancy Cohort (Raine) Study and both random-effects and fixed-effects models, this study examined the connection between maternal work hours and child overweight or obesity. Following children in two-parent families from early childhood to early adolescence, multivariate analyses revealed a non-linear and developmentally dynamic relationship. Among preschool children (ages 2 to 5), we found lower likelihood of child overweight and obesity when mothers worked 24 h or less per week, compared to when mothers worked 35 or more hours...
August 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28548201/-morphine-induced-biliary-pain-case-report
#19
Zoltán Berger, Mario Arcos, Fernanda Matamala, Claudia Rojas
Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consulted in the emergency room for severe low abdominal pain of gynecologic origin, which was completely controlled by morphine. However, she presented a sudden epigastric colicky pain irradiating in the back, which persisted for several hours in spite of the repeated administration of analgesics...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28521318/breastfeeding-childhood-asthma-and-allergic-disease
#20
Wendy H Oddy
The worldwide prevalence of childhood asthma has been increasing considerably, and the protection afforded by breastfeeding in its development has been the subject of controversy for more than 80 years. Previous systematic reviews have generally found a protective effect of breastfeeding on allergic outcomes, although many studies have methodological limitations. Although breastfeeding is protective against lower respiratory tract infection during infancy, such protection has not been demonstrated for asthma in all studies...
2017: Annals of Nutrition & Metabolism
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