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https://www.readbyqxmd.com/read/29780117/a-case-of-gangliocytic-paraganglioma-with-carcinoma-of-the-ampulla-of-vater-a-case-report
#1
Masanari Sekine, Hiroyuki Miyatani, Keita Matsumoto, Hitomi Kashima, Yudai Koito, Takaya Miura, Yuko Takahashi, Rumiko Tsuboi, Takehiro Ishii, Junichi Fujiwara, Takeshi Uehara, Shunsuke Urayoshi, Kazuhito Yuhashi, Takeharu Asano, Noriyoshi Sagihara, Satohiro Matsumoto, Hirosato Mashima
The patient was a "73" -year-old woman who visited our hospital with the chief complaint of weight loss. Upper gastrointestinal endoscopy revealed an enlarged ampulla of Vater, and a biopsy led to a diagnosis of Group "4" gastric carcinoma; suspicious of adenocarcinoma. There were no findings suggesting invasion into the muscle layer of duodenum, despite tumor mass formation being observed in the sphincter of Oddi. We performed endoscopic papillectomy for both diagnostic and therapeutic purposes...
May 18, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29769608/rapid-parallel-evolution-overcomes-global-honey-bee-parasite
#2
Melissa Oddie, Ralph Büchler, Bjørn Dahle, Marin Kovacic, Yves Le Conte, Barbara Locke, Joachim R de Miranda, Fanny Mondet, Peter Neumann
In eusocial insect colonies nestmates cooperate to combat parasites, a trait called social immunity. However, social immunity failed for Western honey bees (Apis mellifera) when the ectoparasitic mite Varroa destructor switched hosts from Eastern honey bees (Apis cerana). This mite has since become the most severe threat to A. mellifera world-wide. Despite this, some isolated A. mellifera populations are known to survive infestations by means of natural selection, largely by supressing mite reproduction, but the underlying mechanisms of this are poorly understood...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29738374/effect-of-interleukin-1-blockade-on-left-ventricular-systolic-performance-and-work-a-post-hoc-pooled-analysis-of-two-clinical-trials
#3
Leo F Buckley, Salvatore Carbone, Cory R Trankle, Justin M Canada, Claudia Oddi Erdle, Jessica A Regan, Michele M Viscusi, Dinesh Kadariya, Hayley Billingsley, Ross Arena, Antonio Abbate, Benjamin W Van Tassell
BACKGROUND: Interleukin-1 (IL-1) blockade appears to improve anaerobic exercise in patients with systolic heart failure through improved left ventricular systolic performance. However, it is unclear whether IL-1 blockade affects left ventricular systolic performance. METHODS: We pooled data from two clinical trials of patients with systolic heart failure who were randomized to IL-1 blockade or placebo. We estimated changes in left ventricular systolic performance (left ventricular ejection fraction [LVEF] and end-systolic elastance [LVEes]) and pressure-volume area, a surrogate of oxygen consumption, after 14 days of treatment...
April 30, 2018: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/29730174/a-systematic-review-of-the-aetiology-and-management-of-post-cholecystectomy-syndrome
#4
REVIEW
Jennifer Isherwood, Kathryn Oakland, Achal Khanna
BACKGROUND: 10% of patients who undergo a cholecystectomy go on to develop post-cholecystectomy syndrome (PCS). The majority of these patients may suffer from extra-biliary or unrelated organic disorders that may have been present before cholecystectomy. The numerous aetiological causes of PCS result in a wide spectrum of management options, each with varying success in abating symptoms. This systematic review aims to provide a summary of the causative aetiologies of post cholecystectomy syndrome, their incidences and efficacy of available management options...
May 2, 2018: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29726053/feather-mites-play-a-role-in-cleaning-host-feathers-new-insights-from-dna-metabarcoding-and-microscopy
#5
Jorge Doña, Heather Proctor, David Serrano, Kevin P Johnson, Arnika Oddy-van Oploo, Jose C Huguet-Tapia, Marina S Ascunce, Roger Jovani
Parasites and other symbionts are crucial components of ecosystems, regulating host populations and supporting food webs. However, most symbiont systems, especially those involving commensals and mutualists, are relatively poorly understood. In this study, we have investigated the nature of the symbiotic relationship between birds and their most abundant and diverse ectosymbionts: the vane-dwelling feather mites. For this purpose, we studied the diet of feather mites using two complementary methods. First, we used light microscopy to examine the gut contents of 1,300 individual feather mites representing 100 mite genera (18 families) from 190 bird species belonging to 72 families and 19 orders...
May 3, 2018: Molecular Ecology
https://www.readbyqxmd.com/read/29703532/the-effect-of-cigarette-smoking-on-the-clinical-and-serological-phenotypes-of-polymyositis-and-dermatomyositis
#6
Adam Schiffenbauer, Sara Faghihi-Kashani, Terrence P O'Hanlon, Willy A Flegel, Sharon D Adams, Ira N Targoff, Chester V Oddis, Steven R Ytterberg, Rohit Aggarwal, Lisa Christopher-Stine, Ejaz A Shamim, Paul F Dellaripa, Sonye K Danoff, Andrew L Mammen, Frederick W Miller
OBJECTIVE: Cigarette smoking is associated with immune-mediated disorders. We explored the contribution of smoking to polymyositis (PM) and dermatomyositis (DM) phenotypes and attempted to determine whether cigarette smoking effects differ by race and genotype. METHODS: Associations of tobacco smoking with disease features, autoantibodies, HLA types, and race were evaluated using multiple logistic regressions in 465 patients. RESULTS: Caucasian ever-smokers (n = 140) were more likely to have PM (adjusted OR = 2...
February 14, 2018: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29700981/telocytes-and-interstitial-cells-of-cajal-in-the-biliary-system
#7
REVIEW
Lei Chen, Baoping Yu
A novel type of interstitial tissue cells in the biliary tree termed telocytes (TCs), formerly known as interstitial Cajal-like cells (ICLCs), exhibits very particular features which unequivocally distinguish these cells from interstitial cells of Cajal (ICCs) and other interstitial cell types. Current research substantiates the existence of TCs and ICCs in the biliary system (gallbladder, extrahepatic bile duct, cystic duct, common bile duct and sphincter of Oddi). Here, we review the distribution, morphology and ultrastructure of TCs and ICCs in the biliary tree, with emphasis on their presumptive roles in physiological and pathophysiological processes...
April 26, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29697044/international-emergency-medical-teams-training-workshop-special-report
#8
Anthony Albina, Laura Archer, Marlène Boivin, Hilarie Cranmer, Kirsten Johnson, Gautham Krishnaraj, Anali Maneshi, Lisa Oddy, Lynda Redwood-Campbell, Rebecca Russell
The World Health Organization's (WHO; Geneva, Switzerland) Emergency Medical Team (EMT) Initiative created guidelines which define the basic procedures to be followed by personnel and teams, as well as the critical points to discuss before deploying a field hospital. However, to date, there is no formal standardized training program established for EMTs before deployment. Recognizing that the World Association of Disaster and Emergency Medicine (WADEM; Madison, Wisconsin USA) Congress brings together a diverse group of key stakeholders, a pre-Congress workshop was organized to seek out collective expertise and to identify key EMT training competencies for the future development of training programs and protocols...
April 26, 2018: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29681437/comparison-of-locking-versus-nonlocking-plates-for-distal-fibula-fractures
#9
Shirley A Lyle, Catherine Malik, Michael J Oddy
Locking plates might offer a biomechanical fixation advantage for distal fibula fractures with comminution or osteoporotic bone. In January 2011, our unit introduced a bone-specific locking plate for the distal fibula. The aim of the present study was to compare it against more conventional plating system implants for lateral malleolar fixation in terms of outcomes, crude costs, and complications. We retrospectively reviewed a consecutive cohort of patients with closed ankle fractures who presented within a 24-month period...
April 19, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29644734/editorial-the-sphincter-of-oddi-strikes-again-eluxadoline-illuminates-a-controversial-mechanism-for-the-pathogenesis-of-acute-pancreatitis
#10
EDITORIAL
G A Coté
No abstract text is available yet for this article.
May 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29617052/retinopathy-of-prematurity-screening-at-%C3%A2-30-weeks-urinary-ntpro-bnp-performance
#11
J E Berrington, P Clarke, N D Embleton, A K Ewer, R Geethanath, S Gupta, M Lal, S Oddie, A Shafiq, C Vasudevan, C Bührer
AIM: Urinary N-terminal B-type natriuretic peptide NTproBNP levels are associated with the development of retinopathy of prematurity (ROP) in infants <30 weeks gestation. The incidence of ROP in more mature infants who meet other ROP screening criteria is very low. We therefore aimed to test whether urinary NTproBNP predicted ROP development in these infants. METHODS: Prospective observational study in 151 UK infants ≥30+0 weeks gestation but also <32 weeks gestation and/or <1501g, to test the hypothesis that urinary NTproBNP levels on day of life (DOL) 14 and 28 were able to predict ROP development...
April 4, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29606668/rituximab-in-the-treatment-of-interstitial-lung-disease-associated-with-antisynthetase-syndrome-a-multicenter-retrospective-case-review
#12
Tracy J Doyle, Namrata Dhillon, Rachna Madan, Fernanda Cabral, Elaine A Fletcher, Diane C Koontz, Rohit Aggarwal, Juan C Osorio, Ivan O Rosas, Chester V Oddis, Paul F Dellaripa
OBJECTIVE: To assess clinical outcomes including imaging findings on computed tomography (CT), pulmonary function testing (PFT), and glucocorticoid (GC) use in patients with the antisynthetase syndrome (AS) and interstitial lung disease (ILD) treated with rituximab (RTX). METHODS: We retrospectively identified all patients at 2 institutions with AS-ILD who were treated with RTX. Baseline demographics, PFT, and chest CT were assessed before and after RTX. Two radiologists independently evaluated CT using a standardized scoring system...
April 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29593343/treatment-in-myositis
#13
REVIEW
Chester V Oddis, Rohit Aggarwal
As with the treatment of many immune-mediated diseases, managing myositis encompasses diverse factors, which present a challenge to the physician caring for these patients. The idiopathic inflammatory myopathies (IIMs, also known as myositis), are fundamentally heterogeneous; many contributory immunological perturbations are involved in the pathogenesis of myositis, leading to varying clinical phenotypic presentations. Targeting any one or several of these deleterious pathways with a therapeutic agent might seem reasonable, but the desired response is not uniformly predictable...
March 29, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29589178/anterior-robotic-approach-in-en-bloc-sacrectomy-a-preliminary-experience
#14
Giacomo Corrado, Carmine Zoccali, Nicola Salducca, Andrea Oddi, Enrico Vizza, Roberto Biagini
En-bloc sacrectomy is a highly demanding surgical procedure necessary to obtain wide margin in sacral tumor. The double approach, anterior and posterior approach, is usually preferred for tumors extending proximally to S3 level where iliac internal vessels are at a higher risk for damage during posterior surgery. It can be justified also in selected cases to decrease the risk of posterior approach as in local recurrence or in patients who already underwent laparotomy. Our intent was to apply robotic-assisted techniques for performing anterior preparatory approach for sacrectomy surgery...
March 27, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29536056/clinical-patterns-of-postcholecystectomy-syndrome
#15
Bader Hamza Shirah, Hamza Asaad Shirah, Syed Husham Zafar, Khalid B Albeladi
Backgrounds/Aims: Postcholecystectomy syndrome represents a heterogeneous group of symptoms and findings in patients who have previously undergone cholecystectomy. It is rare and under-reported in Saudi Arabia. It can be attributed to many complications such as bile duct injury, biliary leak, retained common bile duct stones, recurrent bile duct stones, and bile duct strictures. In this study, we aimed to analyze the causes and evaluate the approach to postcholecystectomy syndrome in our local Saudi Arabian community because of the vast number of cases encountered in our hospital for gallbladder clinical conditions and its related complications...
February 2018: Annals of Hepato-Biliary-Pancreatic Surgery
https://www.readbyqxmd.com/read/29513895/are-prophylactic-antibiotics-necessary-prior-to-transarterial-chemoembolization-for-hepatocellular-carcinoma-in-patients-with-native-biliary-anatomy
#16
Jennifer M Watchmaker, Andrew J Lipnik, Micah R Fritsche, Jennifer C Baker, Samdeep K Mouli, Sunil Geevarghese, Filip Banovac, Reed A Omary, Daniel B Brown
BACKGROUND AND OBJECTIVES: Prophylactic antibiotics are frequently administered for transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC). In patients without previous biliary instrumentation, infection risk from TACE is low. We hypothesized that there is a negligible rate of infection in these patients without prophylactic antibiotics. METHODS: We reviewed consecutive patients undergoing TACE between 7/1/2013-6/15/2016. All patients had an intact Sphincter of Oddi, received no peri-procedural antibiotics, and had 30+ days follow-up...
March 7, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29499900/does-preserved-sphincter-of-oddi-function-prevent-common-bile-duct-stones-recurrence-in-patients-after-endoscopic-papillary-balloon-dilation
#17
Tzung-Jiun Tsai, Chiun-Ku Lin, Kwok-Hung Lai, Hoi-Hung Chan, E-Ming Wang, Wei-Lun Tsai, Jin-Shiung Cheng, Hsien-Chung Yu, Wen-Chi Chen, Ping-I Hsu
BACKGROUND: Whether preserving sphincter of Oddi (SO) function by endoscopic papillary balloon dilation (EPBD) is beneficial for preventing recurrent common bile duct stone disease (CBDS) is controversial. The aim of this study was to measure sphincter of Oddi (SO) function by using SO manometry, and to evaluate the association with recurrent CBDS. METHODS: Patients with suspected CBDS who underwent successful EPBD were included. These patients underwent SO manometry at two months after EPBD with bile duct clearance...
April 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29496924/drs-aggarwal-and-oddis-reply
#18
Rohit Aggarwal, Chester V Oddis
No abstract text is available yet for this article.
March 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29486266/social-modulation-of-risky-decision-making-in-rats-rattus-norvegicus-and-tufted-capuchin-monkeys-sapajus-spp
#19
F Zoratto, G Oddi, E Gori, A Micucci, F De Petrillo, F Paglieri, W Adriani, G Laviola, E Addessi
Both human and non-human animals frequently deal with risky decisions in a social environment. Nevertheless, the influence of the social context on decision-making has been scarcely investigated. Here, we evaluated for the first time whether the presence of a conspecific influences risk preferences in rats and in tufted capuchin monkeys. Subjects received a series of choices between a constant, safe option and a variable, risky option, both alone (Alone condition) and when paired with a conspecific (Paired condition)...
February 24, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29472987/adult-female-with-symptomatic-avpr2-related-nephrogenic-syndrome-of-inappropriate-antidiuresis-nsiad
#20
Jennifer Hague, Ruth Casey, Jonathan Bruty, Tom Legerton, Stephen Abbs, Susan Oddy, Andrew S Powlson, Mohamed Majeed, Mark Gurnell, Soo-Mi Park, Helen Simpson
Activating mutations in AVPR2 are associated with nephrogenic syndrome of inappropriate antidiuresis (NSIAD). NSIAD causes hyponatremia, decreased serum osmolality and clinical symptoms, which may present from birth or in infancy and include hypotonia, irritability, vomiting and/or seizures. Symptoms in later life are often less specific and include malaise, dizziness, confusion, tiredness and headache. NSIAD is a rare X-linked condition, which is associated with a variable phenotype in males, of whom some present in infancy but others do not become symptomatic until adulthood, or occasionally, never...
2018: Endocrinology, Diabetes & Metabolism Case Reports
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