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psychotic symptoms in alcoholics,psychotic symptoms in substance used patients

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https://www.readbyqxmd.com/read/29282872/psychotic-spectrum-symptoms-cumulative-adversity-exposure-and-substance-use-among-high-risk-girls
#1
Amy E Lansing, Wendy Y Plante, Christine Fennema-Notestine, Shahrokh Golshan, Audrey N Beck
AIM: Psychotic-spectrum symptoms are linked to trauma, substance/alcohol use (SAU), criminality/violence and poor functional outcomes, supporting the need for early detection in vulnerable populations. To better understand high-risk girls' mental health, we assessed: (1) psychotic-spectrum symptoms; (2) cumulative trauma, adversity and loss exposures (C-TALE) and adversity-indicators (symptoms, maladaptive coping, stressor-reactivity); and SAU risk-factors; and (3) relationships among psychotic-spectrum symptoms, adversity-indicators and SAU risk-factors...
December 28, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29275216/mdpv-in-forensic-routine-cases-psychotic-and-aggressive-behavior-in-relation-to-plasma-concentrations
#2
Marco Diestelmann, Anna Zangl, Inge Herrle, Eva Koch, Matthias Graw, Liane D Paul
The new psychoactive substance 3,4-methylenedioxypyrovalerone (MDPV) belongs to the group of synthetic cathinones and is purchased mainly as "research chemical" or "bath salt" on the illegal drug market, also in South Bavaria. MDPV was detected in blood and urine samples from 2010 on in 50 authentic routine cases in a forensic setting. Plasma concentrations in 46 cases with available blood specimens ranged from approximately 1.0 to 301μg/L (median 23.7; mean 47.9μg/L), detected by a fully validated LC-MS/MS method...
December 8, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29227894/substance-induced-psychotic-symptoms-in-borderline-personality-disorder-among-substance-use-disorder-samples-in-spain
#3
Carmen Barral, Laia Rodríguez-Cintas, Lara Grau-López, Constanza Daigre, Elena Ros-Cucurull, Natalia Calvo, Marc Ferrer, Carlos Roncero
Substance-induced psychosis (SIP) is frequent in substance use disorder patients. However, little is known about the presence of SIP in Borderline Personality Disorder (BPD) and what the risk factors for the development of SIP in this population would be. A sample of 91 BPD drug-dependent patients attending an outpatient substance use disorder unit was evaluated. Comorbidity with Axis I and II was assessed using SCID-I and SCID-II. Psychoactive drug related variables were registered as well as the presence of the ninth criterion of DSM-IV-TR as a code of psychotic symptoms...
December 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29065847/long-term-administration-of-antipsychotic-drugs-in-schizophrenia-and-influence-of-substance-and-drug-abuse-on-the-disease-outcome
#4
F-M Werner, Rafael Coveñas
BACKGROUND: Many schizophrenic patients with a long-term administration of antipsychotic drugs do not regularly adhere to the prescribed pharmacotherapy. Antipsychotic drugs constitute a palliative, but not a curative treatment, and the long-term effect of these drugs is not secure. Patients tend to consume nicotine and alcohol, as well as some patients consume drugs such as cannabis and amphetamines. OBJECTIVE: The objective of this mini-review is to examine the reasons for the high tendency of schizophrenic patients to consume alcohol, nicotine and drugs and in addition to suggest measures to reduce the abuse of substances and drugs...
October 20, 2017: Current Drug Abuse Reviews
https://www.readbyqxmd.com/read/28962668/tailor-tapered-discontinuation-versus-maintenance-therapy-of-antipsychotic-medication-in-patients-with-newly-diagnosed-schizophrenia-or-persistent-delusional-disorder-in-remission-of-psychotic-symptoms-study-protocol-for-a-randomized-clinical-trial
#5
Anne Emilie Stürup, Heidi Dorthe Jensen, Signe Dolmer, Merete Birk, Nikolai Albert, Mai Nielsen, Carsten Hjorthøj, Lene Eplov, Bjørn H Ebdrup, Ole Mors, Merete Nordentoft
BACKGROUND: The aim of the TAILOR trial is to investigate the effect of closely monitored tapering/discontinuation versus maintenance therapy with antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorder and with minimum 3 months' remission of psychotic symptoms. METHODS AND DESIGN: Two hundred and fifty patients will be included from the psychiatric early intervention program, OPUS, in two regions in Denmark. Inclusion criteria are: ICD-10 diagnoses schizophrenia (F20, except F20...
September 29, 2017: Trials
https://www.readbyqxmd.com/read/28697856/demographic-and-clinical-correlates-of-substance-use-disorders-in-first-episode-psychosis
#6
Mary F Brunette, Kim T Mueser, Steven Babbin, Piper Meyer-Kalos, Robert Rosenheck, Christoph U Correll, Corrine Cather, Delbert G Robinson, Nina R Schooler, David L Penn, Jean Addington, Sue E Estroff, Jennifer Gottlieb, Shirley M Glynn, Patricia Marcy, James Robinson, John M Kane
BACKGROUND: We assessed the prevalence and correlates of lifetime substance use disorders in people with first episode psychosis using the baseline data from the Recovery After an Initial Schizophrenia Episode (RAISE) Early Treatment Program study. METHODS: Research staff assessed 404 first episode patients at 34 community mental health centers across the United States with the Structured Clinical Interview for DSM-IV for diagnoses of psychotic and substance use disorders...
July 8, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28531646/lifetime-presence-of-psychotic-symptoms-in-bipolar-disorder-is-associated-with-less-favorable-socio-demographic-and-certain-clinical-features
#7
Bernardo Dell'Osso, Giulia Camuri, Laura Cremaschi, Cristina Dobrea, Massimiliano Buoli, Terence A Ketter, A Carlo Altamura
BACKGROUND: The presence of psychotic symptoms in bipolar disorder (BD) is considered a feature of higher severity of illness and, in particular, of manic episodes in bipolar I disorder (BD I). However, the possibility to apply the "with psychotic features" specifier to major depressive episodes in either bipolar II disorder (BD II) or BD I highlights the need for additional research in this area. METHODS: The present study assessed the lifetime presence of psychotic symptoms and related socio-demographic and clinical features in a large sample of BD patients (N=360), with (BDPs, N=207) and without a lifetime history of psychosis (BDNPs, N=153)...
July 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28419959/substance-abuse-in-patients-with-bipolar-disorder-a-systematic-review-and-meta-analysis
#8
REVIEW
Thomas Messer, Gero Lammers, Florian Müller-Siecheneder, Raluca-Florela Schmidt, Sahar Latifi
By considering the debilitating outcome of co-occurring of bipolar disorder (BD) and substance abuse, determination of risk factors of substance use disorders (SUD: abuse or dependence of drugs and/or alcohol) is essential to identify the susceptible patients. The purpose of this study was to clarify the major determinant factors of SUD among adults with BD by reviewing the relevant literature. We systematically searched electronic databases including PubMed (MEDLINE), EMBASE, OVID, Cochrane and Scopus for human studies addressing the co-existence of bipolar disorder and SUD...
April 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28287773/alcohol-use-and-service-utilization-among-veterans-in-treatment-for-schizophrenia
#9
Eric R Pedersen, Wenjing Huang, Amy N Cohen, Alexander S Young
Comorbid alcohol and drug use disorders are treatable and have substantial effects on outcomes and health care utilization in people with schizophrenia. While these substance use disorders (SUDs) are thought to be common in patients with schizophrenia, it has been difficult to characterize prevalence and treatment utilization of this population, since administrative data and medical records may not identify patients with schizophrenia who have an SUD diagnosis. In this study, we used an in-person, population-based survey of 801 individuals with schizophrenia who were in treatment within the Veterans Health Administration (VHA) to inform service delivery for patients with these problems...
March 13, 2017: Psychological Services
https://www.readbyqxmd.com/read/28099526/executive-functioning-in-men-with-schizophrenia-and-substance-use-disorders-influence-of-lifetime-suicide-attempts
#10
Ana Adan, Maria Del Mar Capella, Gemma Prat, Diego A Forero, Silvia López-Vera, José Francisco Navarro
BACKGROUND: Lifetime suicide attempts in patients with comorbidity between psychotic disorders and Substance Use Disorder (SUD), known as dual diagnosis, was associated with a worse clinical and cognitive state, poor prognosis and premature death. However, to date no previous study has examined the cognitive performance of these patients considering as independent the presence or absence of lifetime suicide attempts. METHODS: We explore executive functioning differences between suicide attempters and non-attempters in dual schizophrenia (DS) patients and the possible related factors for both executive performance and current suicide risk...
2017: PloS One
https://www.readbyqxmd.com/read/28078209/cognitive-behavioural-therapy-for-obsessive-compulsive-disorder-co-occurring-with-psychosis-systematic-review-of-evidence
#11
Antonio Tundo, Roberta Necci
AIM: To review available evidence on the use of cognitive behavioural therapy (CBT) for treating obsessive compulsive disorder co-occurring with psychosis. METHODS: In this paper we present a detailed and comprehensive review of the current literature focusing on CBT treatment of obsessive compulsive disorder (OCD) co-occurring with schizophrenia or schizoaffective disorder. We identified relevant literature published between 2001 and May 2016 through MEDLINE/PubMed search using as search string ("obsessive compulsive disorders" or "obsessive compulsive symptoms") and ("schizophrenia" or "schizoaffective disorder" or "psychosis") and ("cognitive behavioural therapy")...
December 22, 2016: World Journal of Psychiatry
https://www.readbyqxmd.com/read/27752345/an-acute-in-patient-psychiatric-service-for-16-to-17-year-old-adolescents-in-the-uk-a-descriptive-evaluation
#12
REVIEW
Venu Duddu, Abdulhakim Rhouma, Masood Qureshi, Imran Bashir Chaudhry, Terry Drake, Altaf Sumra, Nusrat Husain
Aims and method The need for an age-appropriate in-patient service for 16- to 17-year-olds led to the development of a 6-bed acute admissions unit in a non-metropolitan county in the UK. We provide a descriptive evaluation of the first 2 years of its operation. All admissions from April 2010 to March 2012 were reviewed, clinical details systematically recorded and descriptively analysed. Results Ninety-seven young people were admitted during this period (a third were compulsorily detained under the Mental Health Act 1983)...
October 2016: BJPsych Bulletin
https://www.readbyqxmd.com/read/27698553/professionals-perception-on-the-management-of-patients-with-dual-disorders
#13
Carlos Roncero, Néstor Szerman, Antonio Terán, Carlos Pino, José María Vázquez, Elena Velasco, Marta García-Dorado, Miguel Casas
BACKGROUND: There is a need to evaluate the professionals' perception about the consequences of the lack of therapeutic adherence in the evolution of patients with co-occurring disorders. METHODS: An online survey, released on the Socidrogalcohol [Spanish Scientific Society for Research on Alcohol, Alcoholism and other Drug Addictions] and Sociedad Española de Patología Dual [the Spanish Society of Dual Pathology] web pages, was answered by 250 professionals who work in different types of Spanish health centers where dual diagnosis patients are assisted...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27650399/the-effects-of-cigarette-smoking-behavior-and-psychosis-history-on-general-and-social-cognition-in-bipolar-disorder
#14
Luz H Ospina, Manuela Russo, George M Nitzburg, Armando Cuesta-Diaz, Megan Shanahan, Mercedes M Perez-Rodriguez, Meaghan Mcgrath, Hannah Levine, Sandra Mulaimovic, Katherine E Burdick
OBJECTIVES: Several studies have documented the prevalence and effects of cigarette smoking on cognition in psychotic disorders; fewer have focused on bipolar disorder (BD). Cognitive and social dysfunction are common in BD, and the severity of these deficits may be related both to illness features (e.g., current symptoms, psychosis history) and health-related behaviors (e.g., smoking, alcohol use). The current study assessed the influence of cigarette smoking on general and social cognition in a BD cohort, accounting for illness features with a focus on psychosis history...
September 2016: Bipolar Disorders
https://www.readbyqxmd.com/read/27541608/the-psychiatric-inclusion-and-exclusion-criteria-in-placebo-controlled-monotherapy-trials-of-bipolar-depression-an-analysis-of-studies-of-the-past-20%C3%A2-years
#15
Mark Zimmerman, Carolina Guzman Holst, Heather L Clark, Matthew Multach, Emily Walsh, Lia K Rosenstein, Douglas Gazarian
BACKGROUND: Concerns about the generalizability of pharmacotherapy efficacy trials to "real-world" patients have been raised for more than 40 years. Almost all of this literature has focused on treatment studies of major depressive disorder (MDD). OBJECTIVE: The aim of the study was to review the psychiatric inclusion and exclusion criteria used in placebo-controlled trials that assessed the efficacy of medications for bipolar depression (bipolar disorder efficacy trials [BDETs]) and compare the criteria used in BDETs with those used in efficacy trials of antidepressants to treat MDD (antidepressant efficacy trials [AETs])...
December 2016: CNS Drugs
https://www.readbyqxmd.com/read/27423358/differential-effects-of-sex-on-substance-use-between-first-episode-psychosis-patients-and-healthy-people
#16
Christian Núñez, Susana Ochoa, Elena Huerta-Ramos, Iris Baños, Ana Barajas, Montserrat Dolz, Bernardo Sánchez, Núria Del Cacho, Judith Usall
BACKGROUND: Substance use in psychosis is an important field of study given that it can be a risk factor for the development of psychosis and can give rise to psychotic symptoms. Studies of substance use in first episode psychosis patients do not frequently assess non-pathological substance consumption among patients, but rather the prevalence of substance abuse or dependence disorders. Moreover, most of these studies do not address the effects of sex in sufficient depth, and the consumption of caffeine or tobacco, which are two of the most frequently used substances, is often not assessed...
August 2016: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/27337422/cannabis-and-neuropsychiatry-2-the-longitudinal-risk-of-psychosis-as-an-adverse-outcome
#17
Chittaranjan Andrade
Psychosis is one of the most serious among the adverse effects associated with cannabis use. The association between cannabis use and psychosis has been variously explored in a series of recent meta-analyses. The results of these meta-analyses show that persons who develop psychosis experience onset of psychosis about 2-3 years earlier if they are cannabis users; this effect is not observed with alcohol or other substance use. Higher levels of cannabis use are associated with greater risk of psychosis. Current cannabis abuse or dependence (but not past use or lower levels of current use) increases the risk of transition into psychosis in persons at ultrahigh risk of psychosis...
June 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27015036/effectiveness-of-inhaled-loxapine-in-dual-diagnosis-patients-a-case-series
#18
Carlos Roncero, Elena Ros-Cucurull, Lara Grau-López, Christian Fadeuilhe, Miguel Casas
OBJECTIVES: Episodes of psychotic agitation are frequent in patients with dual diagnosis, that is, in patients with concomitant psychiatric and substance use disorders. Rapid intervention is needed to treat the agitation at a mild stage to prevent the escalation to aggressive behavior. Inhaled loxapine has been demonstrated to rapidly improve symptoms of mild-to-moderate agitation in adults with psychiatric disorders (schizophrenia and bipolar disorder), but data on patients with dual diagnosis are scarce...
July 2016: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/26600573/the-study-of-primary-psychotic-disorders-with-concurrent-substance-abuse-in-terms-of-their-diagnostic-stability
#19
Ankit Singal, P S Bhat, K Srivastava, Jyoti Prakash
BACKGROUND: Co-morbid substance use is common among individuals presenting with symptoms of psychosis. There is a paucity of research in this area. AIM: To study the longitudinal follow-up of patients over 1-year of first episode psychosis with concurrent substance use in terms of their diagnostic stability. MATERIALS AND METHODS: Fifty patients having at least one symptom of psychosis at first admission at a General Hospital Psychiatric Unit along with concurrent substance abuse were included and followed up for 1-year...
July 2015: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/26417473/psychopathology-in-substance-use-disorder-patients-with-and-without-substance-induced-psychosis
#20
Simon Zhornitsky, Andràs Tikàsz, Élie Rizkallah, Jean-Pierre Chiasson, Stéphane Potvin
Background. Substance-induced psychotic disorder (SIPD) is a diagnosis constructed to distinguish substance-induced psychotic states from primary psychotic disorders. A number of studies have compared SIPD persons with primary psychotic patients, but there is little data on what differentiates substance use disorder (SUD) individuals with and without SIPD. Here, we compared psychopathology, sociodemographic variables, and substance use characteristics between SUD patients with and without SIPD. Methods. A retrospective chart review was conducted on newly admitted patients at a rehabilitation centre between 2007 and 2012...
2015: Journal of Addiction
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