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https://www.readbyqxmd.com/read/29448465/universal-scaling-and-nonlinearity-of-aggregate-price-impact-in-financial-markets
#1
Felix Patzelt, Jean-Philippe Bouchaud
How and why stock prices move is a centuries-old question still not answered conclusively. More recently, attention shifted to higher frequencies, where trades are processed piecewise across different time scales. Here we reveal that price impact has a universal nonlinear shape for trades aggregated on any intraday scale. Its shape varies little across instruments, but drastically different master curves are obtained for order-volume and -sign impact. The scaling is largely determined by the relevant Hurst exponents...
January 2018: Physical Review. E
https://www.readbyqxmd.com/read/29444609/optimization-of-resources-by-drug-management-a-multicentred-web-administered-study-on-the-use-of-ipilimumab-in-italy
#2
V Damuzzo, A Russi, M Chiumente, C Masini, B Rebesco, F Gregis, S Nozza, J Pigozzo, V Chiarion-Sileni, A C Palozzo
Objective In a scenario of new expensive cancer therapies entering the market, strategies of optimisation and cost containment are crucial in oncology care. Better management of drug waste and centralization of drug preparation can be effective strategies to achieve these goals. The aim of this work is to describe the economic management of a high cost anticancer drug (ipilimumab) in some Italian reference centres. Methods This was an observational, multicentred study in which economical and clinical data of 21 cancer centres (418 patients) were collected during the enrollment period from February 2013 to August 2014...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29444140/getting-to-fp2020-harnessing-the-private-sector-to-increase-modern-contraceptive-access-and-choice-in-ethiopia-nigeria-and-drc
#3
Christina Riley, Danielle Garfinkel, Katherine Thanel, Keith Esch, Endale Workalemahu, Jennifer Anyanti, Godéfroid Mpanya, Arsène Binanga, Jen Pope, Kim Longfield, Jane Bertrand, Bryan Shaw
BACKGROUND: An estimated 214 million women have unmet need for family planning in developing regions. Improved utilization of the private sector is key to achieving universal access to a range of safe and effective modern contraceptive methods stipulated by FP2020 and SDG commitments. Until now, a lack of market data has limited understanding of the private sector's role in increasing contraceptive coverage and choice. METHODS: In 2015, the FPwatch Project conducted representative outlet surveys in Ethiopia, Nigeria, and DRC using a full census approach in selected administrative areas...
2018: PloS One
https://www.readbyqxmd.com/read/29420645/the-role-of-global-economic-policy-uncertainty-in-long-run-volatilities-and-correlations-of-u-s-industry-level-stock-returns-and-crude-oil
#4
Honghai Yu, Libing Fang, Boyang Sun
We investigate how Global Economic Policy Uncertainty (GEPU) drives the long-run components of volatilities and correlations in crude oil and U.S. industry-level stock markets. Using the modified generalized autoregressive conditional heteroskedasticity mixed data sampling (GARCH-MIDAS) and dynamic conditional correlation mixed data sampling (DCC-MIDAS) specifications, we find that GEPU is positively related to the long-run volatility of Financials and Consumer Discretionary industries; however, it is negatively related to Information Technology, Materials, Telecommunication Services and Energy...
2018: PloS One
https://www.readbyqxmd.com/read/29420644/inference-of-financial-networks-using-the-normalised-mutual-information-rate
#5
Yong Kheng Goh, Haslifah M Hasim, Chris G Antonopoulos
In this paper, we study data from financial markets, using the normalised Mutual Information Rate. We show how to use it to infer the underlying network structure of interrelations in the foreign currency exchange rates and stock indices of 15 currency areas. We first present the mathematical method and discuss its computational aspects, and apply it to artificial data from chaotic dynamics and to correlated normal-variates data. We then apply the method to infer the structure of the financial system from the time-series of currency exchange rates and stock indices...
2018: PloS One
https://www.readbyqxmd.com/read/29420584/a-novel-stock-forecasting-model-based-on-high-order-fuzzy-fluctuation-trends-and-back-propagation-neural-network
#6
Hongjun Guan, Zongli Dai, Aiwu Zhao, Jie He
In this paper, we propose a hybrid method to forecast the stock prices called High-order-fuzzy-fluctuation-Trends-based Back Propagation(HTBP)Neural Network model. First, we compare each value of the historical training data with the previous day's value to obtain a fluctuation trend time series (FTTS). On this basis, the FTTS blur into fuzzy time series (FFTS) based on the fluctuation of the increasing, equality, decreasing amplitude and direction. Since the relationship between FFTS and future wave trends is nonlinear, the HTBP neural network algorithm is used to find the mapping rules in the form of self-learning...
2018: PloS One
https://www.readbyqxmd.com/read/29413584/decision-making-financial-risk-aversion-and-behavioral-biases-the-role-of-testosterone-and-stress
#7
John R Nofsinger, Fernando M Patterson, Corey A Shank
We examine the relation between testosterone, cortisol, and financial decisions in a sample of naïve investors. We find that testosterone level is positively related to excess risk-taking, whereas cortisol level is negatively related to excess risk-taking (correlation coefficient [r]: 0.75 and -0.21, respectively). Additionally, we find support for the dual-hormone hypothesis in a financial context. Specifically, the testosterone-to-cortisol ratio is significantly related to loss aversion. Individuals with a higher ratio are 3...
January 27, 2018: Economics and Human Biology
https://www.readbyqxmd.com/read/29376341/occurrence-of-organophosphorus-flame-retardants-and-plasticizers-pfrs-in-belgian-foodstuff-and-estimation-of-the-dietary-exposure-of-the-adult-population
#8
Giulia Poma, Carlos Sales, Bram Bruyland, Christina Christia, Severine Goscinny, Joris Van Loco, Adrian Covaci
The occurrence of 14 organophosphorus flame retardants and plasticizers (PFRs) was investigated in 165 composite food samples purchased from the Belgian market and divided in 14 food categories, including fish, crustaceans, mussels, meat, milk, cheese, dessert, food for infants, fats and oils, grains, eggs, potatoes and derived products, other food (stocks) and vegetables. Seven PFRs [namely, tri-n-butyl phosphate (TnBP), tris (2-chloroethyl) phosphate (TCEP), tris (1-chloro-2-propyl) phosphate (TCIPP), tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), triphenyl phosphate (TPHP), 2-ethylhexyl diphenyl phosphate (EHDPHP) and tris (2-ethylhexyl) phosphate (TEHP)] were detected at concentrations above quantification limits...
January 27, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29370279/the-genetics-of-overwintering-performance-in-two-year-old-common-carp-and-its-relation-to-performance-until-market-size
#9
Martin Prchal, Antti Kause, Marc Vandeputte, David Gela, Jean-Michel Allamellou, Girish Kumar, Anastasia Bestin, Jérôme Bugeon, Jinfeng Zhao, Martin Kocour
Using farmed common carp, we investigated the genetic background of the second year overwintering performance and its relation to the performance during the third growing season and at market size. The experimental stock was established by partial factorial design with a series of 4 factorial matings of 5 dams and 10 sires each. The families were reared communally and pedigree was re-constructed with 93.6% success using 12 microsatellites on 2008 offspring. Three successive recordings (second autumn, third spring, and third autumn-market size) covering two periods (second overwintering, third growing season) were included...
2018: PloS One
https://www.readbyqxmd.com/read/29369661/progressive-taxation-income-inequality-and-happiness
#10
Shigehiro Oishi, Kostadin Kushlev, Ulrich Schimmack
Income inequality has become one of the more widely debated social issues today. The current article explores the role of progressive taxation in income inequality and happiness. Using historical data in the United States from 1962 to 2014, we found that income inequality was substantially smaller in years when the income tax was more progressive (i.e., a higher tax rate for higher income brackets), even when controlling for variables like stock market performance and unemployment rate. Time lag analyses further showed that higher progressive taxation predicted increasingly lower income inequality up to 5 years later...
January 25, 2018: American Psychologist
https://www.readbyqxmd.com/read/29347332/linear-and-nonlinear-market-correlations-characterizing-financial-crises-and-portfolio-optimization
#11
Alexander Haluszczynski, Ingo Laut, Heike Modest, Christoph Räth
Pearson correlation and mutual information-based complex networks of the day-to-day returns of U.S. S&P500 stocks between 1985 and 2015 have been constructed to investigate the mutual dependencies of the stocks and their nature. We show that both networks detect qualitative differences especially during (recent) turbulent market periods, thus indicating strongly fluctuating interconnections between the stocks of different companies in changing economic environments. A measure for the strength of nonlinear dependencies is derived using surrogate data and leads to interesting observations during periods of financial market crises...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346931/equation-based-model-for-the-stock-market
#12
Paloma O C Xavier, A P F Atman, A R Bosco de Magalhães
We propose a stock market model which is investigated in the forms of difference and differential equations whose variables correspond to the demand or supply of each agent and to the price. In the model, agents are driven by the behavior of their trust contact network as well by fundamental analysis. By means of the deterministic version of the model, the connection between such drive mechanisms and the price is analyzed: imitation behavior promotes market instability, finitude of resources is associated to stock index stability, and high sensitivity to the fair price provokes price oscillations...
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29342451/decadal-changes-in-the-edible-supply-of-seafood-and-methylmercury-exposure-in-the-united-states
#13
Elsie M Sunderland, Miling Li, Kurt Bullard
BACKGROUND: Methylmercury (MeHg) exposure is associated with adverse effects on neurodevelopment and cardiovascular health. Previous work indicates most MeHg is from marine fish sold in the commercial market, but does not fully resolve supply regions globally. This information is critical for linking changes in environmental MeHg levels to human exposure in the U.S. population. OBJECTIVES: We used available data to estimate the geographic origins of seafood consumed in the United States (major ocean basins, coastal fisheries, aquaculture, freshwater) and how shifts in edible supply affected MeHg exposures between 2000-2002 and 2010-2012...
January 16, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29341493/modeling-the-downstream-processing-of-monoclonal-antibodies-reveals-cost-advantages-for-continuous-methods-for-a-broad-range-of-manufacturing-scales
#14
Jonathan Hummel, Mark Pagkaliwangan, Xhorxhi Gjoka, Terence Davidovits, Rick Stock, Thomas Ransohoff, Rene Gantier, Mark Schofield
The biopharmaceutical industry is evolving in response to changing market conditions, including increasing competition and growing pressures to reduce costs. Single-use technologies and continuous bioprocessing have attracted attention as potential facilitators of cost-optimized manufacturing for monoclonal antibodies. While disposable bioprocessing has been adopted at many scales of manufacturing, continuous bioprocessing has yet to reach the same level of implementation. In this study, the cost of goods of Pall Life Science's integrated, continuous bioprocessing platform was modeled, along with that of purification processes in stainless-steel and single-use batch formats...
January 17, 2018: Biotechnology Journal
https://www.readbyqxmd.com/read/29334016/case-report-to-demonstrate-the-need-for-selection-criteria-for-optimal-adjustable-velcro-wrap-prescription
#15
Suzie Ehmann, Karen Bock
Compression, in the form of either a compression bandage or a compression stocking, has been touted as the gold standard for treatment of swelling and venous leg ulcers (VLUs). Adjustable Velcro wraps have been marketed as compression alternative. Although there is a growing body of evidence to support use of these products, there has not been a critical evaluation of the functionality of the devices to best matching product to patient presentation and ability to use the device effectively. Unlike compression garments, which are classified by compression category (class I/II or flat knit/circular), there is not an algorithm to direct health professionals to best match a specific adjustable Velcro wrap to an individual patient presentation...
January 1, 2018: Journal of Wound Care
https://www.readbyqxmd.com/read/29281619/shortages-of-benzathine-penicillin-for-prevention-of-mother-to-child-transmission-of-syphilis-an-evaluation-from-multi-country-surveys-and-stakeholder-interviews
#16
Stephen Nurse-Findlay, Melanie M Taylor, Margaret Savage, Maeve B Mello, Sanni Saliyou, Manuel Lavayen, Frederic Seghers, Michael L Campbell, Françoise Birgirimana, Leopold Ouedraogo, Morkor Newman Owiredu, Nancy Kidula, Lee Pyne-Mercier
BACKGROUND: Benzathine penicillin G (BPG) is the only recommended treatment to prevent mother-to-child transmission of syphilis. Due to recent reports of country-level shortages of BPG, an evaluation was undertaken to quantify countries that have experienced shortages in the past 2 years and to describe factors contributing to these shortages. METHODS AND FINDINGS: Country-level data about BPG shortages were collected using 3 survey approaches. First, a survey designed by the WHO Department of Reproductive Health and Research was distributed to 41 countries and territories in the Americas and 41 more in Africa...
December 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29250836/mr-scanning-tattoo-inks-and-risk-of-thermal-burn-an-experimental-study-of-iron-oxide-and-organic-pigments-effect-on-temperature-and-magnetic-behavior-referenced-to-chemical-analysis
#17
K K Alsing, H H Johannesen, R Hvass Hansen, M Dirks, O Olsen, J Serup
BACKGROUND: Tattooed persons examined with magnetic resonance imaging (MRI) can develop burning sensation suggested in the literature to be thermal burn from the procedure. MRI-induced thermal effect and magnetic behavior of known tattoo pigments were examined ex vivo. MATERIALS AND METHODS: Magnetic resonance imaging effects on 3 commonly used commercial ink stock products marketed for cosmetic tattooing was studied. A main study tested 22 formulations based on 11 pigment raw materials, for example, one line of 11 called pastes and another called dispersions...
December 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/29246208/when-it-just-won-t-go-away-oral-artemisinin-monotherapy-in-nigeria-threatening-lives-threatening-progress
#18
Chinazo Ujuju, Jennifer Anyanti, Paul N Newton, Godwin Ntadom
BACKGROUND: Oral artemisinin monotherapy (AMT), an important contributor to multi-drug resistant malaria, has been banned in Nigeria. While oral AMT has scarcely been found for several years now in other malaria-endemic countries, availability has persisted in Nigeria's private sector. In 2015, the ACTwatch project conducted a nationally representative outlet survey. Results from the outlet survey show the extent to which oral AMT prevails in Nigeria's anti-malarial market, and provide key product information to guide strategies for removal...
December 15, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29240783/fluctuation-driven-price-dynamics-and-investment-strategies
#19
Yan Li, Bo Zheng, Ting-Ting Chen, Xiong-Fei Jiang
Investigation of the driven mechanism of the price dynamics in complex financial systems is important and challenging. In this paper, we propose an investment strategy to study how dynamic fluctuations drive the price movements. The strategy is successfully applied to different stock markets in the world, and the result indicates that the driving effect of the dynamic fluctuations is rather robust. We investigate how the strategy performance is influenced by the market states and optimize the strategy performance by introducing two parameters...
2017: PloS One
https://www.readbyqxmd.com/read/29238886/poultry-production-and-constraints-in-eastern-province-of-rwanda-case-study-of-rukomo-sector-nyagatare-district
#20
Eugene Mazimpaka, Micheal Tukei, Anselme Shyaka, Eugene N Gatari
A study was conducted in Rukomo sector, Nyagatare district, to determine the status of poultry production. A structured questionnaire was used to collect data from 100 poultry farmers randomly as 20 farmers from each of the five cells. Data were analyzed using SPSS version 16 and presented in chart and tables. The majority of the farmers (84%) reared their poultry in free range system while 10% practiced semi-intensive and only 6% did intensive production. Only 12% of the respondents kept exotic poultry breeds...
December 14, 2017: Tropical Animal Health and Production
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