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https://www.readbyqxmd.com/read/29220034/just-how-good-an-investment-is-the-biopharmaceutical-sector
#1
Richard T Thakor, Nicholas Anaya, Yuwei Zhang, Christian Vilanilam, Kien Wei Siah, Chi Heem Wong, Andrew W Lo
Uncertainty surrounding the risk and reward of investments in biopharmaceutical companies poses a challenge to those interested in funding such enterprises. Using data on publicly traded stocks, we track the performance of 1,066 biopharmaceutical companies from 1930 to 2015-the most comprehensive financial analysis of this sector to date. Our systematic exploration of methods for distinguishing biotech and pharmaceutical companies yields a dynamic, more accurate classification method. We find that the performance of the biotech sector is highly sensitive to the presence of a few outlier companies, and confirm that nearly all biotech companies are loss-making enterprises, exhibiting high stock volatility...
December 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/29212108/-the-aut-idem-rule-and-the-importance-of-patient-individual-selection-of-inhalers-for-the-therapy-of-airway-diseases-in-practices-of-pneumologists-and-general-practitioners-assessment-and-implementation-by-pneumologists-and-general-practitioners
#2
T Hering, J Andres, C Mohrlang, M Redeker, E Schwarz
Drug therapy of obstructive airway diseases mainly relies on inhaled medication. The success of this therapy depends primarily on the selection of the appropriate inhaler considering patient's choice and the correct application. The aut-idem-rule, an active exclusion of the optional substitution by the pharmacist, allows prescribing physicians to ensure the delivery of a particular inhaler, which was selected for that patient, who was trained to use specifically that inhaler. This survey shows that pneumologists and, to a greater extent general practitioners, do not consistently make use of this option, although they unanimously agree on the importance of targeted inhaler selection...
December 6, 2017: Pneumologie
https://www.readbyqxmd.com/read/29209498/intensifying-poultry-production-systems-and-the-emergence-of-avian-influenza-in-china-a-one-health-ecohealth-epitome
#3
Marius Gilbert, Xiangming Xiao, Timothy P Robinson
Several kinds of pressure can lead to the emergence of infectious diseases. In the case of zoonoses emerging from livestock, one of the most significant changes that has taken place since the mid twentieth century is what has been termed the "livestock revolution", whereby the stock of food animals, their productivity and their trade has increased rapidly to feed rising and increasingly wealthy and urbanized populations. Further increases are projected in the future in low and middle-income countries. Using avian influenza as an example, we discuss how the emergence of avian influenza H5N1 and H7N9 in China was linked to rapid intensification of the poultry sector taking place in landscapes rich in wetland agriculture and wild waterfowls habitats, providing an extensive interface with the wild reservoir of avian influenza viruses...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29201565/age-based-and-reproductive-biology-of-the-pacific-longnose-parrotfish-hipposcarus-longiceps-from-guam
#4
Brett M Taylor, Eric Cruz
The Pacific longnose parrotfish Hipposcarus longiceps (Valenciennes 1840) represents a prime fishery resource throughout much of the tropical Pacific. In this study, we sampled the species from the Guam commercial fishery market across five consecutive years to characterize reproductive and age-based demographic information imperative for informed fishery management. Compared with other parrotfishes, this species was found to be large-bodied, but has only a moderate life span of 10 + years. Hipposcarus longiceps was confirmed as a diandric protogynous hermaphrodite with highly sex-specific growth patterns and an overall mean asymptotic length of 434 mm fork length (FL)...
2017: PeerJ
https://www.readbyqxmd.com/read/29190696/asymmetry-of-price-returns-analysis-and-perspectives-from-a-non-extensive-statistical-physics-point-of-view
#5
Łukasz Bil, Dariusz Grech, Magdalena Zienowicz
We study how the approach grounded on non-extensive statistical physics can be applied to describe and distinguish different stages of the stock and money market development. A particular attention is given to asymmetric behavior of fat tailed distributions of positive and negative returns. A new method to measure this asymmetry is proposed. It is based on the value of the non-extensive Tsallis parameter q. The new quantifier of the relative asymmetry level between tails in terms of the Tsallis parameters q± is provided to analyze the effect of memory in data caused by nonlinear autocorrelations...
2017: PloS One
https://www.readbyqxmd.com/read/29143591/the-machine-in-the-market-computers-and-the-infrastructure-of-price-at-the-new-york-stock-exchange-1965-1975
#6
Devin Kennedy
This article traces the development and expansion of early computer systems for managing and disseminating 'real-time' market data at the most influential stock market in the United States, the New York Stock Exchange (NYSE). It follows electronic media at the NYSE over a roughly ten-year period, from the time of the deployment of a computer called the Market Data System (MDS) through debates surrounding the National Market System and the passage of the 1975 Securities Acts Amendments. Building on research at the archives of the NYSE and the Securities and Exchange Commission (SEC), this history emphasizes the regulatory and managerial contexts in which market data became computerized...
December 2017: Social Studies of Science
https://www.readbyqxmd.com/read/29139129/reproductive-biology-of-female-striped-marlin-kajikia-audax-in-the-western-pacific-ocean
#7
H-Y Chang, C-L Sun, S-Z Yeh, Y-J Chang, N-J Su, G DiNardo
Length and mass data for 1260 (536 females, 683 males, 41 sex unknown) striped marlin Kajikia audax were collected at the fish markets of Tungkang, Singkang and Nanfangao from July 2004 to September 2010. Of these samples, 534 gonads (236 females and 298 males) ranging from 95 to 206 cm in eye-to-fork length (LEF ) and 8 to 88 kg in round mass (MR ), were collected. Chi-square tests indicated sex ratios were homogeneous among months in 2004 and 2006-2008, but not in 2005, 2009 and 2010; and there were significant differences in sex ratio by size...
November 15, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/29136004/predictability-of-machine-learning-techniques-to-forecast-the-trends-of-market-index-prices-hypothesis-testing-for-the-korean-stock-markets
#8
Sujin Pyo, Jaewook Lee, Mincheol Cha, Huisu Jang
The prediction of the trends of stocks and index prices is one of the important issues to market participants. Investors have set trading or fiscal strategies based on the trends, and considerable research in various academic fields has been studied to forecast financial markets. This study predicts the trends of the Korea Composite Stock Price Index 200 (KOSPI 200) prices using nonparametric machine learning models: artificial neural network, support vector machines with polynomial and radial basis function kernels...
2017: PloS One
https://www.readbyqxmd.com/read/29121113/facial-width-to-height-ratio-differs-by-social-rank-across-organizations-countries-and-value-systems
#9
Tim Hahn, Nils R Winter, Christine Anderl, Karolien Notebaert, Alina Marie Wuttke, Celina Chantal Clément, Sabine Windmann
Facial Width-to-Height Ratio (fWHR) has been linked with dominant and aggressive behavior in human males. We show here that on portrait photographs published online, chief executive officers (CEOs) of companies listed in the Dow Jones stock market index and the Deutscher Aktienindex have a higher-than-normal fWHR, which also correlates positively with their company's donations to charitable causes and environmental awareness. Furthermore, we show that leaders of the world's most influential non-governmental organizations and even the leaders of the Roman Catholic Church, the popes, have higher fWHR compared to controls on public portraits, suggesting that the relationship between displayed fWHR and leadership is not limited to profit-seeking organizations...
2017: PloS One
https://www.readbyqxmd.com/read/29111226/marketing-food-and-beverages-to-youth-through-sports
#10
REVIEW
Marie A Bragg, Christina A Roberto, Jennifer L Harris, Kelly D Brownell, Brian Elbel
Food and beverage marketing has been identified as a major driver of obesity yet sports sponsorship remains common practice and represents millions of dollars in advertising expenditures. Research shows that food and beverage products associated with sports (e.g., M&M's with National Association for Stock Car Auto Racing logo) generate positive feelings, excitement, and a positive self-image among adults and children. Despite this, self-regulatory pledges made by food companies to limit exposure of unhealthy products to children have not improved the nutritional quality of foods marketed to children...
October 27, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29100687/distinguishing-the-vegetation-dynamics-induced-by-anthropogenic-factors-using-vegetation-optical-depth-and-avhrr-ndvi-a-cross-border-study-on-the-mongolian-plateau
#11
Xiang Zhou, Yasushi Yamaguchi, Sanjiwana Arjasakusuma
Distinguishing the vegetation dynamics induced by anthropogenic factors and identifying the major drivers can provide crucial information for designing actionable and practical countermeasures to restore degraded grassland ecosystems. Based on the residual trend (RESTREND) method, this study distinguished the vegetation dynamics induced by anthropogenic factors from the effects of climate variability on the Mongolian Plateau during 1993-2012 using vegetation optical depth (VOD) and normalized difference vegetation index (NDVI), which measure vegetation water content in aboveground biomass and chlorophyll abundance in canopy cover respectively; afterwards, the major drivers within different agricultural zones and socio-institutional periods were identified by integrating agricultural statistics with statistical analysis techniques...
October 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29095894/suicides-as-a-response-to-adverse-market-sentiment-1980-2016
#12
Pankaj Agrrawal, Doug Waggle, Daniel H Sandweiss
Financial crises inflict significant human as well as economic hardship. This paper focuses on the human fallout of capital market stress. Financial stress-induced behavioral changes can manifest in higher suicide and murder-suicide rates. We find that these rates also correlate with the Gross Domestic Product (GDP) growth rate (negatively associated; a -0.25% drop [in the rate of change in annual suicides for a +1% change in the independent variable]), unemployment rate (positive link; 0.298% increase), inflation rate (positive link; 0...
2017: PloS One
https://www.readbyqxmd.com/read/29092631/around-the-corner-to-better-health-a-milwaukee-corner-store-initiative
#13
Staci Young, Melissa DeNomie, JoAnne Sabir, Eric Gass, Jessie Tobin
PURPOSE: To discuss successes and challenges of a collaborative pilot project to increase healthy food availability in corner stores in Milwaukee, Wisconsin. The Lindsay Heights Healthy Corner Store Initiative aimed to help corner stores sell high-quality produce by increasing supply of healthy foods and funding minor store upgrades to facilitate change. DESIGN: Evaluation research. SETTING: Milwaukee, Wisconsin. PARTICIPANTS: Corner stores; youth and adult community members...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29070827/information-connections-among-multiple-investors-evolutionary-local-patterns-revealed-by-motifs
#14
Qing Guan, Haizhong An, Nairong Liu, Feng An, Meihui Jiang
The concept of motifs provides a fresh perspective for studying local patterns, which is useful for understanding the essence of a network structure. However, few previous studies have focused on the evolutionary characteristics of weighted motifs while further considering participants' differences. We study how information connections differ among multiple investors. The evolutionary 10-year trend of weighted 3-motifs in China's energy stock markets is explored for the networks of co-holding behaviors among shareholders, who are classified as companies, funds and individuals...
October 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29070084/productive-economic-and-risk-assessment-of-grazing-dairy-systems-with-supplemented-cows-milked-once-a-day
#15
B Lazzarini, N Lopez-Villalobos, N Lyons, L Hendrikse, J Baudracco
Milking cows once a day (OAD) is a herd management practice that may help to reduce working effort and labour demand in dairy farms. However, a decrease in milk yield per cow occurs in OAD systems compared with twice a day (TAD) systems and this may affect profitability of dairy systems. The objective of this study was to assess productive and economic impact and risk of reducing milking frequency from TAD to OAD for grazing dairy systems, using a whole-farm model. Five scenarios were evaluated by deterministic and stochastic simulations: one scenario under TAD milking (TADAR) and four scenarios under OAD milking...
October 26, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29053822/characterization-of-indigenous-chicken-production-systems-in-rwanda
#16
J Mahoro, T K Muasya, F Mbuza, R Habimana, A K Kahi
Characterization of indigenous chicken (IC) production systems in Rwanda was conducted from November 2015 to January 2016 with the aim of understanding socio-economic characteristics, management of IC, production parameters, feed resources, and constraints faced by farmers rearing IC. A survey involving 206 households was carried out in 5 districts with the highest populations of IC using structured questionnaires. Data were analyzed using SAS software. The results showed that the majority of respondents (62...
September 14, 2017: Poultry Science
https://www.readbyqxmd.com/read/29037730/citrus-fruits-freshness-assessment-using-raman-spectroscopy
#17
Fran Nekvapil, Ioana Brezestean, Daniel Barchewitz, Branko Glamuzina, Vasile Chiş, Simona Cintă Pinzaru
The freshness of citrus fruits commonly available in the market was non-destructively assessed by Raman spectroscopy. Intact clementine, mandarin and tangerine species were characterised concerning their carotenoids skin Raman signalling in a time course from the moment they were acquired as fresh stock, supplying the market, to the physical degradation, when they were no longer attractive to consumers. The freshness was found to strongly correlate to the peel Raman signal collected from the same area of the intact fruits in a time course of a maximum of 20days...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29033782/neural-correlates-of-direct-access-trading-in-a-real-stock-market-an-fmri-investigation
#18
GianMario Raggetti, Maria G Ceravolo, Lucrezia Fattobene, Cinzia Di Dio
Background: While financial decision making has been barely explored, no study has previously investigated the neural correlates of individual decisions made by professional traders involved in real stock market negotiations, using their own financial resources. Aim: We sought to detect how different brain areas are modulated by factors like age, expertise, psychological profile (speculative risk seeking or aversion) and, eventually, size and type (Buy/Sell) of stock negotiations, made through Direct Access Trading (DAT) platforms...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29022708/dynamic-model-for-the-stocks-and-release-flows-of-engineered-nanomaterials
#19
Runsheng Song, Yuwei Qin, Sangwon Suh, Arturo A Keller
Most existing life-cycle release models for engineered nanomaterials (ENM) are static, ignoring the dynamics of stock and flows of ENMs. Our model, nanoRelease, estimates the annual releases of ENMs from manufacturing, use, and disposal of a product explicitly taking stock and flow dynamics into account. Given the variabilities in key parameters (e.g., service life of products and annual release rate during use) nanoRelease is designed as a stochastic model. We apply nanoRelease to three ENMs (TiO2, SiO2 and FeOx) used in paints and coatings through seven product applications, including construction and building, household and furniture, and automotive for the period from 2000 to 2020 using production volume and market projection information...
November 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28992931/livestock-mortality-and-offtake-in-sheep-and-goat-flocks-of-livestock-owners-making-use-of-services-offered-by-paravets-in-west-afghanistan
#20
Chris J M Bartels, A Qader Fakhri, M Hamed Shams, Raymond P Briscoe, Bram E C Schreuder
In the present study, we quantified the effect of livestock services provided through paravets (intermediate-level training in veterinary medicine) on mortality and offtake of small ruminants in Western Afghanistan for the years 2010, 2011 and 2013. We compared mortality in adult and in young stock, and offtake of young stock of 120 livestock owners that made use of the paravet services (Users) with 120 livestock owners who did not make use of these services (Non-users). Security issues in the districts under study influenced the choice of villages...
October 1, 2017: Preventive Veterinary Medicine
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