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https://www.readbyqxmd.com/read/28056656/age-and-pubertal-status-related-changes-in-reports-of-perception-of-personal-odors
#1
Lenka Martinec Nováková, Dagmar Plotěná, Jan Havlíček
As previously suggested, preferences for kin body odor might undergo an adaptive change over the course of puberty in order to avoid potential inbreeding, resulting in aversion to body odor of the opposite-gender kin as individuals mature sexually. However, studies based on mutual body odor aversion are rather inconclusive. We therefore investigated whether children's reports of individuals smelling good or bad differed as a function of age and pubertal status. We asked 219 children (94 male) aged 10 to 15 years to assess their pubertal development using a standardized measure and to name individuals they thought smelled good or bad...
January 1, 2017: Perception
https://www.readbyqxmd.com/read/28053896/effects-of-4-week-continuous-ingestion-of-champignon-extract-on-halitosis-and-body-and-fecal-odor
#2
Jun Nishihira, Mie Nishimura, Aiko Tanaka, Akihiro Yamaguchi, Toshio Taira
This was placebo-controlled double-blind parallel-group comparative clinical trial targeting 80 men and women aged 50-79 years with halitosis and body and fecal odor. We investigated whether daily champignon extract ingestion for 4 weeks improved these conditions. Subjects were divided into four groups: a placebo group and 50, 500, and 1000 mg/day ingestion groups. No severe adverse events or side effects were noted during the study period. Compared with the placebo group, all champignon extract ingestion groups showed improvement or tendency toward improvement in halitosis and body and fecal odor...
January 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28045639/a-retrospective-cohort-study-of-glossopharyngeal-nerve-taste-in-children-with-recurrent-acute-tonsillitis
#3
Courtney A Hill, Suveera Dang, Michael Beach, Eunice Y Chen
Objective To compare glossopharyngeal taste between healthy children and those with recurrent acute tonsillitis. Study Design Retrospective cohort study. Setting Pediatric clinics in a tertiary care medical center and satellite location. Subjects and Methods Smell and taste testing was administered to 80 well children and 64 children with recurrent acute tonsillitis (age range, 6-17 years). Smell testing was performed with the NIH Toolbox Odor Identification Test, with scores based on national averages for age and sex...
January 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28039314/olfaction-and-risk-of-dementia-in-a-biracial-cohort-of-older-adults
#4
Kristine Yaffe, Daniel Freimer, Honglei Chen, Keiko Asao, Andrea Rosso, Susan Rubin, Greg Tranah, Steve Cummings, Eleanor Simonsick
OBJECTIVE: Prior studies indicate that olfactory function may be an early marker for cognitive impairment, but the body of evidence has been largely restricted to white populations. METHODS: We studied 2,428 community-dwelling black and white older adults (baseline age 70-79 years) without dementia enrolled in the Health, Aging, and Body Composition (Health ABC) study. Olfaction was measured as odor identification (OI) with the 12-item Cross Cultural Smell Identification Test in year 3...
December 30, 2016: Neurology
https://www.readbyqxmd.com/read/28028122/evolution-of-chemosensory-gene-families-in-arthropods-insight-from-the-first-inclusive-comparative-transcriptome-analysis-across-spider-appendages
#5
Joel Vizueta, Cristina Frías-López, Nuria Macías-Hernández, Miquel A Arnedo, Alejandro Sánchez-Gracia, Julio Rozas
Unlike hexapods and vertebrates, in chelicerates, knowledge of the specific molecules involved in chemoreception comes exclusively from the comparative analysis of genome sequences. Indeed, the genomes of mites, ticks and spiders contain several genes encoding homologs of some insect membrane receptors and small soluble chemosensory proteins. Here, we conducted for the first time a comprehensive comparative RNA-Seq analysis across different body structures of a chelicerate: the nocturnal wandering hunter spider Dysdera silvatica Schmidt 1981...
December 27, 2016: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28017607/a-simple-computational-model-of-the-bee-mushroom-body-can-explain-seemingly-complex-forms-of-olfactory-learning-and-memory
#6
Fei Peng, Lars Chittka
Honeybees are models for studying how animals with relatively small brains accomplish complex cognition, displaying seemingly advanced (or "non-elemental") learning phenomena involving multiple conditioned stimuli. These include "peak shift" [1-4]-where animals not only respond to entrained stimuli, but respond even more strongly to similar ones that are farther away from non-rewarding stimuli. Bees also display negative and positive patterning discrimination [5], responding in opposite ways to mixtures of two odors than to individual odors...
December 18, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/28005625/a-prospective-study-of-axillary-hair-reduction-in-patients-treated-with-microwave-technology
#7
Jeremy A Brauer, Julia P Neckman, Brian Zelickson, David B Vasily, Roy G Geronemus
BACKGROUND: Removing unwanted body hair is a growing trend in society today, and there are many laser-based devices for hair reduction. There are some limitations to those methods, including the lack of efficacy for lighter color hair. OBJECTIVE: The objective was to quantify hair reduction in the axillae after treatment with a noninvasive microwave energy device. MATERIALS AND METHODS: A prospective, multicenter study was performed at 3 private dermatology clinics...
December 21, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27989835/a-broadly-tuned-odorant-receptor-in-neurons-of-trichoid-sensilla-in-locust-locusta-migratoria
#8
Yinwei You, Dean P Smith, Mingyue Lv, Long Zhang
Insects have evolved sophisticated olfactory reception systems to sense exogenous chemical signals. Odorant receptors (ORs) on the membrane of chemosensory neurons are believed to be key molecules in sensing exogenous chemical cues. ORs in different species of insects are diverse and should tune a species to its own specific semiochemicals relevant to their survival. The orthopteran insect, locust (Locusta migratoria), is a model hemimetabolous insect. There is very limited knowledge on the functions of locust ORs although many locust OR genes have been identified in genomic sequencing experiments...
October 27, 2016: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27981180/enhancement-of-striatum-dependent-memory-by-conditioned-fear-is-mediated-by-beta-adrenergic-receptors-in-the-basolateral-amygdala
#9
Travis D Goode, Kah-Chung Leong, Jarid Goodman, Stephen Maren, Mark G Packard
Emotional arousal can have a profound impact on various learning and memory processes. For example, unconditioned emotional stimuli (e.g., predator odor or anxiogenic drugs) enhance dorsolateral striatum (DLS)-dependent habit memory. These effects critically depend on a modulatory role of the basolateral complex of the amygdala (BLA). Recent work indicates that, like unconditioned emotional stimuli, exposure to an aversive conditioned stimulus (CS) (i.e., a tone previously paired with shock) can also enhance consolidation of DLS-dependent habit memory...
June 2016: Neurobiology of Stress
https://www.readbyqxmd.com/read/27916960/detection-of-volatile-metabolites-derived-from-garlic-allium-sativum-in-human-urine
#10
Laura Scheffler, Yvonne Sauermann, Anja Heinlein, Constanze Sharapa, Andrea Buettner
The metabolism and excretion of flavor constituents of garlic, a common plant used in flavoring foods and attributed with several health benefits, in humans is not fully understood. Likewise, the physiologically active principles of garlic have not been fully clarified to date. It is possible that not only the parent compounds present in garlic but also its metabolites are responsible for the specific physiological properties of garlic, including its influence on the characteristic body odor signature of humans after garlic consumption...
December 1, 2016: Metabolites
https://www.readbyqxmd.com/read/27905515/neonicotinoid-induced-impairment-of-odour-coding-in-the-honeybee
#11
Mara Andrione, Giorgio Vallortigara, Renzo Antolini, Albrecht Haase
Exposure to neonicotinoid pesticides is considered one of the possible causes of honeybee (Apis mellifera) population decline. At sublethal doses, these chemicals have been shown to negatively affect a number of behaviours, including performance of olfactory learning and memory, due to their interference with acetylcholine signalling in the mushroom bodies. Here we provide evidence that neonicotinoids can affect odour coding upstream of the mushroom bodies, in the first odour processing centres of the honeybee brain, i...
December 1, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27884756/repeated-unpredictable-threats-without-harm-impair-spatial-working-memory-in-the-barnes-maze
#12
Diane J Kim, Nathan St Louis, Ralph A Molaro, Glenn T Hudson, Robert C Chorley, Brenda J Anderson
Psychological stressors elicit the anticipation of homeostatic challenge, whereas physical stressors are direct threats to homeostasis. Many rodent models of stress include both types of stressors, yet deficits, like those reported for working memory, are often attributed to psychological stress. To empirically test whether intermittent psychological stressors, such as repeated threats, are solely sufficient to impair spatial working memory, we developed a novel rodent model of stress that is restricted to the anticipation of threat, and free of direct physical challenge...
January 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/27871975/the-role-of-the-drosophila-lateral-horn-in-olfactory-information-processing-and-behavioral-response
#13
REVIEW
Janna N Schultzhaus, Sehresh Saleem, Hina Iftikhar, Ginger E Carney
Animals must rapidly and accurately process environmental information to produce the correct behavioral responses. Reactions to previously encountered as well as to novel but biologically important stimuli are equally important, and one understudied region in the insect brain plays a role in processing both types of stimuli. The lateral horn is a higher order processing center that mainly processes olfactory information and is linked via olfactory projection neurons to another higher order learning center, the mushroom body...
November 19, 2016: Journal of Insect Physiology
https://www.readbyqxmd.com/read/27859193/the-importance-of-motivation-weapons-and-foul-odors-in-driving-encounter-competition-in-carnivores
#14
Maximilian L Allen, Christopher C Wilmers, L Mark Elbroch, Julie M Golla, Heiko U Wittmer
Encounter competition is interference competition in which animals directly contend for resources. Ecological theory predicts the trait that determines the resource holding potential (RHP), and hence the winner of encounter competition, is most often body size or mass. The difficulties of observing encounter competition in complex organisms in natural environments, however, has limited opportunities to test this theory across diverse species. We studied the outcome of encounter competition contests among mesocarnivores at deer carcasses in California to determine the most important variables for winning these contests...
August 2016: Ecology
https://www.readbyqxmd.com/read/27855167/assessment-of-olfactory-function-in-mapt-associated-neurodegenerative-disease-reveals-odor-identification-irreproducibility-as-a-non-disease-specific-general-characteristic-of-olfactory-dysfunction
#15
Katerina Markopoulou, Bruce A Chase, Piotr Robowski, Audrey Strongosky, Ewa Narożańska, Emilia J Sitek, Mariusz Berdynski, Maria Barcikowska, Matt C Baker, Rosa Rademakers, Jarosław Sławek, Christine Klein, Katja Hückelheim, Meike Kasten, Zbigniew K Wszolek
Olfactory dysfunction is associated with normal aging, multiple neurodegenerative disorders, including Parkinson's disease, Lewy body disease and Alzheimer's disease, and other diseases such as diabetes, sleep apnea and the autoimmune disease myasthenia gravis. The wide spectrum of neurodegenerative disorders associated with olfactory dysfunction suggests different, potentially overlapping, underlying pathophysiologies. Studying olfactory dysfunction in presymptomatic carriers of mutations known to cause familial parkinsonism provides unique opportunities to understand the role of genetic factors, delineate the salient characteristics of the onset of olfactory dysfunction, and understand when it starts relative to motor and cognitive symptoms...
2016: PloS One
https://www.readbyqxmd.com/read/27831646/mechanism-of-feedback-regulation-of-neutrophil-inflammation-in-henoch-sch%C3%A3-nlein-purpura
#16
J-J Wu, Y-T Zhu, Y-M Hu
OBJECTIVE: The aim of this study is to investigate the role of complement-neutrophil feedback regulation of inflammatory response in Henoch-Schönlein purpura (HSP) through constructing an animal model of HSP. MATERIALS AND METHODS: Twenty-four SPF grade Japanese large-eared white rabbits were randomly divided into normal group and model group, 12 for each group. HSP model was constructed by challenging rabbits with gastric gavage of a decoction solution containing ginger, Piper longum L...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27815144/a-broadly-tuned-odorant-receptor-in-neurons-of-trichoid-sensilla-in-locust-locusta-migratoria
#17
Yinwei You, Dean P Smith, Mingyue Lv, Long Zhang
Insects have evolved sophisticated olfactory reception systems to sense exogenous chemical signals. Odorant receptors (ORs) on the membrane of chemosensory neurons are believed to be key molecules in sensing exogenous chemical cues. ORs in different species of insects are diverse and should tune a species to its own specific semiochemicals relevant to their survival. The orthopteran insect, locust (Locusta migratoria), is a model hemimetabolous insect. There is very limited knowledge on the functions of locust ORs although many locust OR genes have been identified in genomic sequencing experiments...
October 27, 2016: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27776190/antennal-transcriptome-and-differential-expression-analysis-of-five-chemosensory-gene-families-from-the-asian-honeybee-apis-cerana-cerana
#18
Huiting Zhao, Yali Du, Pengfei Gao, Shujie Wang, Jianfang Pan, Yusuo Jiang
Chemosensory genes play a central role in sensing chemical signals and guiding insect behavior. The Chinese honeybee, Apis cerana cerana, is one of the most important insect species in China in terms of resource production, and providing high-quality products for human consumption, and also serves as an important pollinator. Communication and foraging behavior of worker bees is likely linked to a complex chemosensory system. Here, we used transcriptome sequencing on adult A. c. cerana workers of different ages to identify the major chemosensory gene families and the differentially expressed genes(DEGs), and to investigate their expression profiles...
2016: PloS One
https://www.readbyqxmd.com/read/27768692/genetic-dissection-of-aversive-associative-olfactory-learning-and-memory-in-drosophila-larvae
#19
Annekathrin Widmann, Marc Artinger, Lukas Biesinger, Kathrin Boepple, Christina Peters, Jana Schlechter, Mareike Selcho, Andreas S Thum
Memory formation is a highly complex and dynamic process. It consists of different phases, which depend on various neuronal and molecular mechanisms. In adult Drosophila it was shown that memory formation after aversive Pavlovian conditioning includes-besides other forms-a labile short-term component that consolidates within hours to a longer-lasting memory. Accordingly, memory formation requires the timely controlled action of different neuronal circuits, neurotransmitters, neuromodulators and molecules that were initially identified by classical forward genetic approaches...
October 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27744049/crispr-cas9-in-locusts-successful-establishment-of-an-olfactory-deficiency-line-by-targeting-the-mutagenesis-of-an-odorant-receptor-co-receptor-orco
#20
Yan Li, Jie Zhang, Dafeng Chen, Pengcheng Yang, Feng Jiang, Xianhui Wang, Le Kang
Locusts are important agricultural pests worldwide and regarded as study models for entomology. However, the absence of targeted gene manipulation systems for locusts has restricted their applications for research. Herein, we report the successful use of the CRISPR/Cas9 system to induce a targeted heritable mutagenesis of the migratory locust, Locusta migratoria. The target sequence of gRNA was designed to disrupt the gene encoding the odorant receptor co-receptor (Orco) and examine the roles of the odorant receptor pathway in the locust...
October 12, 2016: Insect Biochemistry and Molecular Biology
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