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https://www.readbyqxmd.com/read/28814616/the-yale-observation-scale-score-and-the-risk-of-serious-bacterial-infections-in-febrile-infants
#1
Lise E Nigrovic, Prashant V Mahajan, Stephen M Blumberg, Lorin R Browne, James G Linakis, Richard M Ruddy, Jonathan E Bennett, Alexander J Rogers, Leah Tzimenatos, Elizabeth C Powell, Elizabeth R Alpern, T Charles Casper, Octavio Ramilo, Nathan Kuppermann
OBJECTIVES: To assess the performance of the Yale Observation Scale (YOS) score and unstructured clinician suspicion to identify febrile infants ≤60 days of age with and without serious bacterial infections (SBIs). METHODS: We performed a planned secondary analysis of a prospective cohort of non-critically ill, febrile, full-term infants ≤60 days of age presenting to 1 of 26 participating emergency departments in the Pediatric Emergency Care Applied Research Network...
June 6, 2017: Pediatrics
https://www.readbyqxmd.com/read/28810357/a-graduated-food-addiction-classification-approach-significantly-differentiates-obesity-among-people-with-type-2-diabetes
#2
Karren-Lee Raymond, Lee Kannis-Dymand, Geoff P Lovell
This study examined a graduated severity level approach to food addiction classification against associations with World Health Organization obesity classifications (body mass index, kg/m(2)) among 408 people with type 2 diabetes. A survey including the Yale Food Addiction Scale and several demographic questions demonstrated four distinct Yale Food Addiction Scale symptom severity groups (in line with Diagnostic and Statistical Manual of Mental Disorders (5th ed.) severity indicators): non-food addiction, mild food addiction, moderate food addiction and severe food addiction...
October 1, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/28759413/the-yale-observation-scale-score-and-the-risk-of-serious-bacterial-infections-in-febrile-infants
#3
Lise E Nigrovic, Prashant V Mahajan, Stephen M Blumberg, Lorin R Browne, James G Linakis, Richard M Ruddy, Jonathan E Bennett, Alexander J Rogers, Leah Tzimenatos, Elizabeth C Powell, Elizabeth R Alpern, T Charles Casper, Octavio Ramilo, Nathan Kuppermann
OBJECTIVES: To assess the performance of the Yale Observation Scale (YOS) score and unstructured clinician suspicion to identify febrile infants ≤60 days of age with and without serious bacterial infections (SBIs). METHODS: We performed a planned secondary analysis of a prospective cohort of non-critically ill, febrile, full-term infants ≤60 days of age presenting to 1 of 26 participating emergency departments in the Pediatric Emergency Care Applied Research Network...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28745944/need-to-screen-for-clinical-levels-of-ocd-four-questions-are-the-key
#4
Judy H Hong, Eric B Lee, Chad T Wetterneck, John M Hart
The aim of this study was to investigate a new measure, the Wetterneck-Hart OCD Screener (WHOS), as a self-report screening tool for obsessive-compulsive disorder (OCD). The authors examined relationships between the WHOS and severity scores of OCD measures taken via three methods of data collection: online, at OCD consumer conferences, and from an intensive, residential OCD program. Severity measures included the Yale-Brown Obsessive-Compulsive Scale-Self Report (Y-BOCS-SR), the Dimensional Obsessive-Compulsive Scale (DOCS), and the Obsessive-Compulsive Inventory-Revised (OCI-R)...
July 26, 2017: Bulletin of the Menninger Clinic
https://www.readbyqxmd.com/read/28707384/a-visual-analog-scale-to-assess-anxiety-in-children-during-anesthesia-induction-vas-i-results-supporting-its-validity-in-a-sample-of-day-care-surgery-patients
#5
Johan M Berghmans, Marten J Poley, Jan van der Ende, Frank Weber, Marc Van de Velde, Peter Adriaenssens, Dirk Himpe, Frank C Verhulst, Elisabeth Utens
BACKGROUND: The modified Yale Preoperative Anxiety Scale is widely used to assess children's anxiety during induction of anesthesia, but requires training and its administration is time-consuming. A Visual Analog Scale, in contrast, requires no training, is easy-to-use and quickly completed. AIM: The aim of this study was to evaluate a Visual Analog Scale as a tool to assess anxiety during induction of anesthesia and to determine cut-offs to distinguish between anxious and nonanxious children...
September 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28673486/quantifying-dimensional-severity-of-obsessive-compulsive-disorder-for-neurobiological-research
#6
Roseli G Shavitt, Guaraci Requena, Pino Alonso, Gwyneth Zai, Daniel L C Costa, Carlos Alberto de Bragança Pereira, Maria Conceição do Rosário, Ivanil Morais, Leonardo Fontenelle, Carolina Cappi, James Kennedy, Jose M Menchon, Euripedes Miguel, Peggy M A Richter
Current research to explore genetic susceptibility factors in obsessive-compulsive disorder (OCD) has resulted in the tentative identification of a small number of genes. However, findings have not been readily replicated. It is now broadly accepted that a major limitation to this work is the heterogeneous nature of this disorder, and that an approach incorporating OCD symptom dimensions in a quantitative manner may be more successful in identifying both common as well as dimension-specific vulnerability genetic factors...
July 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28667830/predictors-of-comorbid-eating-disorders-and-association-with-other-obsessive-compulsive-spectrum-disorders-in-trichotillomania
#7
Erica Greenberg, Jon E Grant, Erin E Curley, Christine Lochner, Douglas W Woods, Esther S Tung, Dan J Stein, Sarah A Redden, Jeremiah M Scharf, Nancy J Keuthen
Trichotillomania (TTM) and eating disorders (ED) share many phenomenological similarities, including ritualized compulsive behaviors. Given this, and that comorbid EDs may represent additional functional burden to hair pullers, we sought to identify factors that predict diagnosis of an ED in a TTM population. Subjects included 555 adult females (age range 18-65) with DSM-IV-TR TTM or chronic hair pullers recruited from multiple sites. 7.2% (N=40) of our TTM subjects met criteria for an ED in their lifetime...
June 21, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28659038/a-randomized-controlled-trial-of-medication-and-cognitive-behavioral-therapy-for-hypochondriasis
#8
RANDOMIZED CONTROLLED TRIAL
Brian A Fallon, David K Ahern, Martina Pavlicova, Iordan Slavov, Natalia Skritskya, Arthur J Barsky
OBJECTIVE: Prior studies of hypochondriasis demonstrated benefits for pharmacotherapy and for cognitive-behavioral therapy (CBT). This study examined whether joint treatment offers additional benefit. METHOD: Patients with DSM-IV hypochondriasis (N=195) were randomly assigned to one of four treatments-placebo, CBT, fluoxetine, or joint treatment with both fluoxetine and CBT. Evaluations assessed hypochondriasis, other psychopathology, adverse events, functional status, and quality of life...
August 1, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28636705/inflammation-in-the-neurocircuitry-of-obsessive-compulsive-disorder
#9
Sophia Attwells, Elaine Setiawan, Alan A Wilson, Pablo M Rusjan, Romina Mizrahi, Laura Miler, Cynthia Xu, Margaret Anne Richter, Alan Kahn, Stephen J Kish, Sylvain Houle, Lakshmi Ravindran, Jeffrey H Meyer
Importance: For a small percentage of obsessive-compulsive disorder (OCD) cases exhibiting additional neuropsychiatric symptoms, it was proposed that neuroinflammation occurs in the basal ganglia as an autoimmune response to infections. However, it is possible that elevated neuroinflammation, inducible by a diverse range of mechanisms, is important throughout the cortico-striato-thalamo-cortical circuit of OCD. Identifying brain inflammation is possible with the recent advance in positron emission tomography (PET) radioligands that bind to the translocator protein (TSPO)...
August 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28577427/fruit-and-vegetable-intake-physical-activity-and-depressive-symptoms-in-the-african-american-health-aah-study
#10
Sandra M L Ribeiro, Theodore K Malmstrom, John E Morley, Douglas K Miller
BACKGROUND: Healthy diet and physical activity (PA) have been associated with reduced depressive symptoms, but few studies have examined them simultaneously in African Americans. AIMS: To investigate fruit and vegetable intake (FVI) and PA as predictors of clinically-relevant levels of depressive symptoms (CRLDS) in African Americans. METHODS: African American Health (AAH) is a population-based longitudinal study of African Americans in St...
October 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28531454/preliminary-validation-of-the-malay-yale-food-addiction-scale-factor-structure-and-item-analysis-in-an-obese-population
#11
Yogarabindranath Swarna Nantha, Norafidza Ashiquin Abd Patah, Mahalakshmi Ponnusamy Pillai
BACKGROUND AND AIMS: Researchers suggest that the rise in obesity rates may be explained by the addictive properties of certain types of food. In view of the growing obesity epidemic in South-East Asia, there is a need for a psychometric tool to assess the concept of food addiction amongst high-risk populations. The objective of this study is to translate the Yale Food Addiction Scale (YFAS) into the Malay language and subsequently validate its use in an obese population. METHODS: Between the year 2014 and 2015, a total of 250 obese adults were assessed for food addiction utilizing the Malay version of the YFAS at a primary care clinic...
December 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28390444/the-relationship-between-obsessive-compulsive-personality-and-obsessive-compulsive-disorder-treatment-outcomes-predictive-utility-and-clinically-significant-change
#12
Shalane K Sadri, Peter M McEvoy, Sarah J Egan, Robert T Kane, Clare S Rees, Rebecca A Anderson
BACKGROUND: The evidence regarding whether co-morbid obsessive compulsive personality disorder (OCPD) is associated with treatment outcomes in obsessive compulsive disorder (OCD) is mixed, with some research indicating that OCPD is associated with poorer response, and some showing that it is associated with improved response. AIMS: We sought to explore the role of OCPD diagnosis and the personality domain of conscientiousness on treatment outcomes for exposure and response prevention for OCD...
April 9, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28382063/the-effects-of-preanesthetic-parental-presence-on-preoperative-anxiety-of-children-and-their-parents-a-randomized-clinical-trial-study-in-iran
#13
Razie Rasti-Emad-Abadi, Abbas Naboureh, Morteza Nasiri, Nilofar Motamed, Faezeh Jahanpour
INTRODUCTION: Parental presence during induction of anesthesia (PPIA) has been a controversial issue, with some studies showing its effects on reducing anxiety. Hence, this study aimed to investigate the effects of PPIA on preoperative anxiety of children as well as their parents. MATERIALS AND METHODS: This clinical trial was conducted among 60 children aged 2-10 years and their parents. Children were randomly assigned to intervention (n = 30) and control (n = 30) groups...
January 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28370722/development-of-the-modified-yale-food-addiction-scale-version-2-0
#14
Erica M Schulte, Ashley N Gearhardt
The Yale Food Addiction Scale (YFAS) operationalizes indicators of addictive-like eating, originally based on the Diagnostic and Statistical Manual of Mental Disorders 4th edition Text Revision (DSM-IV-TR) criteria for substance-use disorders. The YFAS has multiple adaptations, including a briefer scale (mYFAS). Recently, the YFAS 2.0 was developed to reflect changes to diagnostic criteria in the DSM-5. The current study developed a briefer version of the YFAS 2.0 (mYFAS 2.0) using the participant sample from the YFAS 2...
March 29, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28363925/methods-to-decrease-variability-in-histological-scoring-in-placentas-from-a-cohort-of-preterm-infants
#15
Jennifer K Straughen, Dawn P Misra, Linda M Ernst, Adrian K Charles, Samantha VanHorn, Samiran Ghosh, Irina Buhimschi, Catalin Buhimschi, George Divine, Carolyn M Salafia
OBJECTIVE: Reliable semiquantitative assessment of histological placental acute inflammation is problematic, even among experts. Tissue samples in histology slides often show variability in the extent and location of neutrophil infiltrates. We sought to determine whether the variability in pathologists' scoring of neutrophil infiltrates in the placenta could be reduced by the use of 'regions of interest' (ROIs) that break the sample into smaller components. DESIGN: ROIs were identified within stained H&E slides from a cohort of 56 women...
March 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28358599/a-double-blind-randomized-placebo-controlled-pilot-study-of-azithromycin-in-youth-with-acute-onset-obsessive-compulsive-disorder
#16
Tanya K Murphy, Erin M Brennan, Carly Johnco, Ellisa Carla Parker-Athill, Branko Miladinovic, Eric A Storch, Adam B Lewin
OBJECTIVES: Sudden and severe onset of obsessive-compulsive disorder (OCD) may present secondary to infectious and/or immune-mediated triggers. We assessed the preliminary efficacy, tolerability, and safety of azithromycin compared with placebo in the treatment of OCD and associated symptoms in children with pediatric acute-onset neuropsychiatric syndrome (PANS). METHODS: Thirty-one youth aged 4-14 years (M = 8.26 ± 2.78 years, 62.5% male) were randomized to receive either placebo or azithromycin for 4 weeks (10 mg/kg up to 500 mg per day)...
March 30, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28340111/assessment-of-patient-reported-outcome-instruments-to-assess-chronic-low-back-pain
#17
Abhilasha Ramasamy, Mona L Martin, Steven I Blum, Hiltrud Liedgens, Charles Argoff, Rainer Freynhagen, Mark Wallace, Kelly P McCarrier, Donald M Bushnell, Noël V Hatley, Donald L Patrick
Objective.:  To identify patient-reported outcome (PRO) instruments that assess chronic low back pain (cLBP) symptoms (specifically pain qualities) and/or impacts for potential use in cLBP clinical trials to demonstrate treatment benefit and support labeling claims. Design.:  Literature review of existing PRO measures. Methods.:  Publications detailing existing PRO measures for cLBP were identified, reviewed, and summarized. As recommended by the US Food & Drug Administration (FDA) PRO development guidance, standard measurement characteristics were reviewed, including development history, psychometric properties (validity and reliability), ability to detect change, and interpretation of observed changes...
June 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28265120/a-genome-wide-gene-by-trauma-interaction-study-of-alcohol-misuse-in-two-independent-cohorts-identifies-prkg1-as-a-risk-locus
#18
R Polimanti, J Kaufman, H Zhao, H R Kranzler, R J Ursano, R C Kessler, J Gelernter, M B Stein
Traumatic life experiences are associated with alcohol use problems, an association that is likely to be moderated by genetic predisposition. To understand these interactions, we conducted a gene-by-environment genome-wide interaction study (GEWIS) of alcohol use problems in two independent samples, the Army STARRS (STARRS, N=16 361) and the Yale-Penn (N=8084) cohorts. Because the two cohorts were assessed using different instruments, we derived separate dimensional alcohol misuse scales and applied a proxy-phenotype study design...
March 7, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28236739/food-addiction-in-children-associations-with-obesity-parental-food-addiction-and-feeding-practices
#19
T Burrows, J Skinner, M A Joyner, J Palmieri, K Vaughan, A N Gearhardt
Food addiction research in children is limited, and to date addictive-like eating behaviors within families have not been investigated. The aim of this study is to understand factors associated with addictive-like eating in children. The association between food addiction in children with obesity, parental food addiction, and parental feeding practices (i.e., restriction, pressure to eat, monitoring) was investigated. Parents/primary caregivers (aged≥18years) of children aged 5-12years, recruited and completed an online cross-sectional survey including demographics, the Yale Food Addiction Scale (YFAS), and the Child Feeding Questionnaire (CFQ)...
August 2017: Eating Behaviors
https://www.readbyqxmd.com/read/28207915/suicidal-and-death-ideation-among-adults-with-obsessive-compulsive-disorder-presenting-for-intensive-intervention
#20
Eric A Storch, Brian Kay, Monica S Wu, Joshua M Nadeau, Bradley Riemann
BACKGROUND: This study examined the frequency and relation of death and/or suicidal ideation to treatment response in 101 adults with obsessive-compulsive disorder (OCD) presenting for intensive intervention. METHODS: Within 2 days of admission to an intensive treatment program, 101 adults with OCD completed the Yale-Brown Obsessive Compulsive Scale-Self Report, Quick Inventory of Depressive Symptomatology-Self Report, Intolerance of Uncertainty Scale, Obsessive-Compulsive Inventory-Revised, Penn State Worry Questionnaire, and Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form, and were administered the Columbia Suicide Scale by a trained clinician...
February 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
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