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https://www.readbyqxmd.com/read/29040718/the-mcconnell-s-capsular-arteries-and-their-relevance-in-endoscopic-endonasal-approach-to-the-sellar-region
#1
Cristian Ferrareze Nunes, André Beer-Furlan, Francesco Doglietto, Ricardo Luis Carrau, Daniel Monte-Serrat Prevedello
BACKGROUND: The McConnell's capsular arteries (MCCA) were first described in 1953. They consist of medial branches of the cavernous internal carotid artery (ICA) and are divided in anterior and inferior capsular arteries. OBJECTIVE: To highlight the anatomy of the MCCA and its importance in the surgical treatment of tuberculum sellae and planum sphenoidale tumors through an endoscopic endonasal approach. METHODS: Ten cadaveric specimens fixed in formalin and perfused with colored silicone were dissected...
October 13, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29035603/competition-level-not-associated-with-diet-quality-in-marching-artists
#2
Colleen R McConnell, Alyssa McPherson, Kathleen Woolf
Marching artists are a unique group of athletes whose performance can be influenced by nutrition. Because physical demands are thought to be moderate to high, adequate energy and a variety of nutrient-dense foods are needed. The purpose of this study was to examine diet quality, physical activity, and eating behavior of marching artists across elite and non-elite competition levels. This cross-sectional analysis used the validated National Cancer Institute Diet History Questionnaire II, International Physical Activity Questionnaire, and Eating Behavior Patterns Questionnaire...
October 16, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29034505/in-vivo-characterization-of-the-downfield-part-of-1-h-mr-spectra-of-human-brain-at-9-4-t-magnetization-exchange-with-water-and-relation-to-conventionally-determined-metabolite-content
#3
Nicole D Fichtner, Ioannis-Angelos Giapitzakis, Nikolai Avdievich, Ralf Mekle, Daniel Zaldivar, Anke Henning, Roland Kreis
PURPOSE: To perform exchange-rate measurements on the in vivo human brain downfield spectrum (5-10 ppm) at 9.4 T and to compare the variation in concentrations of the downfield resonances and of known upfield metabolites to determine potential peak labels. METHODS: Non-water-suppressed metabolite cycling was used in combination with an inversion transfer technique in two brain locations in healthy volunteers to measure the exchange rates and T1 values of exchanging peaks...
October 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29031482/toxicologic-transport-properties-of-ncs-382-a-%C3%AE-hydroxybutyrate-ghb-receptor-ligand-in-neuronal-and-epithelial-cells-therapeutic-implications-for-ssadh-deficiency-a-gaba-metabolic-disorder
#4
K R Vogel, G R Ainslie, A McConnell, J-B Roullet, K M Gibson
We report the in vitro assessment of pharmacotoxicity for the high-affinity GHB receptor ligand, NCS-382, using neuronal stem cells derived from mice with a targeted deletion of the aldehyde dehydrogenase 5a1 gene (succinic semialdehyde dehydrogenase(SSADH)-deficient mice). These animals represent a phenocopy of the human disorder of GABA metabolism, SSADH deficiency, that metabolically features accumulation of both GABA and the GABA-analog γ-hydroxybutyric acid in conjunction with a nonspecific neurological phenotype...
October 12, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29027239/erratum-a-novel-perfused-bloch-mcconnell-simulator-for-analyzing-the-accuracy-of-dynamic-hyperpolarized-mrs-med-phys-v43-854-864-2016
#5
Christopher M Walker, Yunyun Chen, Stephen Y Lai, James A Bankson
No abstract text is available yet for this article.
October 2017: Medical Physics
https://www.readbyqxmd.com/read/29017757/effects-of-retinoic-acid-signaling-on-extraocular-muscle-myogenic-precursor-cells-in-vitro
#6
Sadie L Hebert, Krysta R Fitzpatrick, Samantha A McConnell, Anja Cucak, Ching Yuan, Linda K McLoon
One major difference between limb and extraocular muscles (EOM) is the presence of an enriched population of Pitx2-positive myogenic precursor cells in EOM compared to limb muscle. We hypothesize that retinoic acid regulates Pitx2 expression in EOM myogenic precursor cells and that its effects would differ in leg muscle. The two muscle groups expressed differential retinoic acid receptor (RAR) and retinoid X receptor (RXR) levels. RXR co-localized with the Pitx2-positive cells but not with those expressing Pax7...
October 7, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/29016245/effect-of-a-high-dosage-opioid-prior-authorization-policy-on-prescription-opioid-use-misuse-and-overdose-outcomes
#7
Daniel M Hartung, Hyunjee Kim, Sharia M Ahmed, Luke Middleton, Shellie Keast, Richard A Deyo, Kun Zhang, K John McConnell
High dosage opioid use is a risk factor for opioid-related overdose commonly cited in guidelines, recommendations, and policies. In 2012, the Oregon Medicaid program developed a prior authorization policy for opioid prescriptions above 120 mg per day morphine equivalent dose (MED). This study aimed to evaluate the effects of that policy on utilization, prescribing patterns, and health outcomes. Methods: Using administrative claims data from Oregon and a control state (Colorado) between 2011 and 2013, we used difference-in-differences analyses to examine changes in utilization, measures of high risk opioid use, and overdose after introduction of the policy...
October 10, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28988689/residency-pathways-to-ambulatory-care-practice-essential-insights-for-students-residents-and-educators
#8
Sarah M Westberg, Stuart J Beatty, Andrea R Corona, Sarah Deines, Karen M Gunning, Holly E Gurgle, Haley S Holtan, Macary Weck Marciniak, Karen J McConnell, Melissa A Somma McGivney, Rachana J Patel
OBJECTIVE: To provide a guiding document describing residency training opportunities in ambulatory care for students, postgraduate year 1 (PGY1) residents, practicing pharmacists, and pharmacy educators. SUMMARY: Student pharmacists, residents, practitioners, and educators can benefit from a guiding document describing the various pathways to develop as an ambulatory care practitioner through residency training. The benefits and differences of PGY1 and postgraduate year 2 (PGY2) ambulatory care residency programs are included...
October 5, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28974206/weekday-snacking-prevalence-frequency-and-energy-contribution-have-increased-while-foods-consumed-during-snacking-have-shifted-among-australian-children-and-adolescents-1995-2007-and-2011-12-national-nutrition-surveys
#9
Flávia Fayet-Moore, Véronique Peters, Andrew McConnell, Peter Petocz, Alison L Eldridge
BACKGROUND: There are limited data on the evolution of eating habits, including snacking, in Australia. This study aimed to understand snacking trends among Australian children over three previous National Nutrition Surveys. METHODS: Data were analysed from a single weekday 24-h recall in the National Nutrition Surveys 1995, 2007, 2011-12 among children 2-16y (n = 8258). A snacking occasion was defined as an eating occasion that occurred between meals based on time of day...
October 3, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28973516/effect-of-promoting-high-quality-staff-interactions-on-fall-prevention-in-nursing-homes-a-cluster-randomized-trial
#10
Cathleen S Colón-Emeric, Kirsten Corazzini, Eleanor S McConnell, Wei Pan, Mark Toles, Rasheeda Hall, Michael P Cary, Melissa Batchelor-Murphy, Tracey Yap, Amber L Anderson, Andrew Burd, Sathya Amarasekara, Ruth A Anderson
Importance: New approaches are needed to enhance implementation of complex interventions for geriatric syndromes such as falls. Objective: To test whether a complexity science-based staff training intervention (CONNECT) promoting high-quality staff interactions improves the impact of an evidence-based falls quality improvement program (FALLS). Design, Setting, and Participants: Cluster-randomized trial in 24 nursing homes receiving either CONNECT followed by FALLS (intervention), or FALLS alone (control)...
October 2, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28965900/methods-employed-for-chest-radiograph-interpretation-education-for-radiographers-a-systematic-review-of-the-literature
#11
REVIEW
L McLaughlin, J McConnell, S McFadden, R Bond, C Hughes
OBJECTIVES: This systematic review aimed to determine the strength of evidence available in the literature on the effect of training to develop the skills required by radiographers to interpret plain radiography chest images. KEY FINDINGS: Thirteen articles feature within the review. Sample size varied from one reporting radiographer to 148 radiography students/experienced radiographers. The quality of the articles achieved a mean score of 7.5/10, indicating the evidence is strong and the quality of studies in this field is high...
November 2017: Radiography
https://www.readbyqxmd.com/read/28965896/could-musculo-skeletal-radiograph-interpretation-by-radiographers-be%C3%A2-a-source-of-support-to-australian-medical-interns-a-quantitative-evaluation
#12
J R McConnell, M A Baird
INTRODUCTION: Public expectations regarding access to the emergency department (ED) challenges providers and policy makers with finite resources being stretched beyond capacity. To enable education of a greater numbers of doctors the format of the medical internship in Australia has changed and assumes that sufficient supervision is provided to interns to enable image interpretation skills development. Furthermore this assumes that appropriate foundational skills are established during undergraduate education...
November 2017: Radiography
https://www.readbyqxmd.com/read/28961820/diminishing-returns-on-intragenic-repeat-number-expansion-in-the-production-of-signalling-peptides
#13
David W Rogers, Ellen McConnell, Eric L Miller, Duncan Greig
Signalling peptides enable communication between cells, both within and between individuals, and are therefore key to the control of complex physiological and behavioural responses. Since their small sizes prevent direct transmission to secretory pathways, these peptides are often produced as part of a larger polyprotein comprising precursors for multiple related or identical peptides; the physiological and behavioural consequences of this unusual gene structure are not understood. Here, we show that the number of mature-pheromone-encoding repeats in the yeast α-mating-factor gene MFα1 varies considerably between closely related isolates of both S...
September 14, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28961773/high-incidence-of-pandrug-resistant-acinetobacter-baumannii-isolates-collected-from-patients-with-ventilator-associated-pneumonia-in-greece-italy-and-spain-as-part-of-the-magicbullet-clinical-trial
#14
J Nowak, E Zander, D Stefanik, P G Higgins, I Roca, J Vila, M J McConnell, J M Cisneros, H Seifert
Objectives: To investigate the molecular epidemiology, antimicrobial susceptibility and carbapenem resistance determinants of Acinetobacter baumannii isolates from respiratory tract samples of patients diagnosed with ventilator-associated pneumonia (VAP) who were enrolled in the MagicBullet clinical trial. Methods: A. baumannii isolates were prospectively cultured from respiratory tract samples from 65 patients from 15 hospitals in Greece, Italy and Spain. Susceptibility testing was performed by broth microdilution...
September 8, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28958150/synthesis-and-characterization-of-tethered-lipid-assemblies-for-membrane-protein-reconstitution-review
#15
Rémi Veneziano, Claire Rossi, Alexandre Chenal, Catherine Brenner, Daniel Ladant, Joël Chopineau
Biological membranes and their related molecular mechanisms are essential for all living organisms. Membranes host numerous proteins and are responsible for the exchange of molecules and ions, cell signaling, and cell compartmentation. Indeed, the plasma membrane delimits the intracellular compartment from the extracellular environment and intracellular membranes. Biological membranes also play a major role in metabolism regulation and cellular physiology (e.g., mitochondrial membranes). The elaboration of membrane based biomimetic systems allows us to reconstitute and investigate, in controlled conditions, biological events occurring at the membrane interface...
September 28, 2017: Biointerphases
https://www.readbyqxmd.com/read/28951152/arcuate-uterus-and-rudimentary-second-uterine-cavity
#16
Katherine L Palmerola, Rachel A McConnell, Beth W Rackow
No abstract text is available yet for this article.
September 22, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28947829/new-zealand-supereruption-provides-time-marker-for-the-last-glacial-maximum-in-antarctica
#17
Nelia W Dunbar, Nels A Iverson, Alexa R Van Eaton, Michael Sigl, Brent V Alloway, Andrei V Kurbatov, Larry G Mastin, Joseph R McConnell, Colin J N Wilson
Multiple, independent time markers are essential to correlate sediment and ice cores from the terrestrial, marine and glacial realms. These records constrain global paleoclimate reconstructions and inform future climate change scenarios. In the Northern Hemisphere, sub-visible layers of volcanic ash (cryptotephra) are valuable time markers due to their widespread dispersal and unique geochemical fingerprints. However, cryptotephra are not as widely identified in the Southern Hemisphere, leaving a gap in the climate record, particularly during the Last Glacial Maximum (LGM)...
September 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28942609/custom-extracellular-matrix-cylinder-mitral-valve-in-a-pediatric-patient
#18
Clifford L Cua, Pace Johnston, Jill Harmon, Kathryn Shelton, Patrick I McConnell
Mitral valve construction using extracellular matrix (ECM) is a relatively new procedure. In this case, a 15-month-old boy with a history of severe mitral valve regurgitation secondary to endocarditis underwent mitral valve surgery. Mitral valve repair was not possible, and thus, a 17 mm extracellular matrix cylinder valve (ECM-CV) was constructed for valve replacement. The ECM-CV is clearly imaged using echocardiography, especially three-dimensional imaging, that helped define valve function. As the use of ECM for valve construction increases, echocardiography will play an essential role in evaluating the function and mechanics of these novel valves...
September 24, 2017: Echocardiography
https://www.readbyqxmd.com/read/28934111/breakfast-and-breakfast-cereal-choice-and-its-impact-on-nutrient-and-sugar-intakes-and-anthropometric-measures-among-a-nationally-representative-sample-of-australian-children-and-adolescents
#19
Flavia Fayet-Moore, Andrew McConnell, Kate Tuck, Peter Petocz
There is limited evidence in Australia that compares the nutritional impact of a breakfast cereal breakfast to a non-cereal breakfast, and includes the type of cereal. This study investigated the impact of breakfast choice and the total sugar content of breakfast cereal on nutrient intakes and anthropometric measures among Australian children and adolescents. Data from 2 to 18-year-old in the 2011-2012 National Nutrition and Physical Activity Survey were used (n = 2821). Participants were classified as breakfast cereal consumers (minimally pre-sweetened (MPS) or pre-sweetened (PS)), non-cereal breakfast consumers, or breakfast skippers...
September 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28930763/a-new-community-health-center-academic-medicine-partnership-for-medicaid-cost-control-powered-by-the-mega-teaching-health-center
#20
Richard E Rieselbach, Ted Epperly, Aaron Friedman, David Keahey, Eleanor McConnell, Karen Nichols, Greg Nycz, Jeanette Roberts, Kenneth Schmader, Peter Shin, Derri Shtasel
Community health centers (CHCs), a principal source of primary care for over 24 million patients, provide high-quality affordable care for medically underserved and lower-income populations in urban and rural communities. The authors propose that CHCs can assume an important role in the quest for health care reform by serving substantially more Medicaid patients. Major expansion of CHCs, powered by mega teaching health centers (THCs) in partnership with regional academic medical centers (AMCs) or teaching hospitals, could increase Medicaid beneficiaries' access to cost-effective care...
September 14, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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