keyword
MENU ▼
Read by QxMD icon Read
search

McConnell

keyword
https://www.readbyqxmd.com/read/28434822/current-and-potential-imaging-applications-of-ferumoxytol-for-magnetic-resonance-imaging
#1
REVIEW
Gerda B Toth, Csanad G Varallyay, Andrea Horvath, Mustafa R Bashir, Peter L Choyke, Heike E Daldrup-Link, Edit Dosa, John Paul Finn, Seymur Gahramanov, Mukesh Harisinghani, Iain Macdougall, Alexander Neuwelt, Shreyas S Vasanawala, Prakash Ambady, Ramon Barajas, Justin S Cetas, Jeremy Ciporen, Thomas J DeLoughery, Nancy D Doolittle, Rongwei Fu, John Grinstead, Alexander R Guimaraes, Bronwyn E Hamilton, Xin Li, Heather L McConnell, Leslie L Muldoon, Gary Nesbit, Joao P Netto, David Petterson, William D Rooney, Daniel Schwartz, Laszlo Szidonya, Edward A Neuwelt
Contrast-enhanced magnetic resonance imaging is a commonly used diagnostic tool. Compared with standard gadolinium-based contrast agents, ferumoxytol (Feraheme, AMAG Pharmaceuticals, Waltham, MA), used as an alternative contrast medium, is feasible in patients with impaired renal function. Other attractive imaging features of i.v. ferumoxytol include a prolonged blood pool phase and delayed intracellular uptake. With its unique pharmacologic, metabolic, and imaging properties, ferumoxytol may play a crucial role in future magnetic resonance imaging of the central nervous system, various organs outside the central nervous system, and the cardiovascular system...
April 14, 2017: Kidney International
https://www.readbyqxmd.com/read/28429404/air-pollution-weight-loss-and-metabolic-benefits-of-bariatric-surgery-a-potential-model-for-study-of-metabolic-effects-of-environmental-exposures
#2
R Ghosh, W J Gauderman, H Minor, H A Youn, F Lurmann, K R Cromar, L Chatzi, B Belcher, C R Fielding, R McConnell
BACKGROUND: Emerging experimental evidence suggests that air pollution may contribute to development of obesity and diabetes, but studies of children are limited. OBJECTIVES: We hypothesized that pollution effects would be magnified after bariatric surgery for treatment of obesity, reducing benefits of surgery. METHODS: In 75 obese adolescents, excess weight loss (EWL), high-density lipoprotein (HDL) cholesterol, triglycerides, alkaline phosphatase (ALP) and hemoglobin A1c (HbA1c ) were measured prospectively at baseline and following laparoscopic adjustable gastric banding (LAGB)...
April 21, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28428008/force-development-and-intracellular-ca-2-in-intact-cardiac-muscles-from-gravin-mutant-mice
#3
Zhitao Li, Sonal Singh, Santosh V Suryavanshi, Wengang Ding, Xiaoxu Shen, Cori S Wijaya, Wei Dong Gao, Bradley K McConnell
Gravin (AKAP12) is an A-kinase-anchoring-protein that scaffolds protein kinase A (PKA), β2-adrenergic receptor (β2-AR), protein phosphatase 2B and protein kinase C. Gravin facilitates β2-AR-dependent signal transduction through PKA to modulate cardiac excitation-contraction coupling and its removal positively affects cardiac contraction. Trabeculae from the right ventricles of gravin mutant (gravin-t/t) mice were employed for force determination. Simultaneously, corresponding intracellular Ca(2+) transient ([Ca(2+)]i) were measured...
April 17, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28426930/subcomponent-exchange-transforms-an-fe-ii-4l4-cage-from-high-to-low-spin-switching-guest-release-in-a-two-cage-system
#4
Anna J McConnell, Catherine M Aitchison, Angela B Grommet, Jonathan R Nitschke
Subcomponent exchange transformed new high-spin Fe(II)4L4 cage 1 into previously-reported low-spin Fe(II)4L4 cage 2: 2-formyl-6-methylpyridine was ejected in favor of the less sterically hindered 2-formylpyridine, with concomitant high- to low-spin transition of the cage's Fe(II) centers. High-spin 1 also reacted more readily with electron-rich anilines than 2, enabling the design of a system consisting of two cages that could release their guests in response to combinations of different stimuli. The addition of p-anisidine to a mixture of high-spin 1 and previously-reported low-spin Fe(II)4L6 cage 3 resulted in the destruction of 1 and the release of its guest...
April 26, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28411324/determinants-of-social-competence-in-pediatric-brain-tumor-survivors-who-participated-in-an-intervention-study
#5
Maru Barrera, Eshetu G Atenafu, Fiona Schulte, Ute Bartels, Lillian Sung, Laura Janzen, Joanna Chung, Danielle Cataudella, Kelly Hancock, Amani Saleh, Douglas Strother, Dina McConnell, Andrea Downie, Juliette Hukin, Shayna Zelcer
PURPOSE: This prospective study describes disease/treatment, personal characteristics, and social/family contextual variables as risk and resilience factors that predict social competence in pediatric brain tumor survivors (PBTS). METHODS: Ninety-one PBTS (51% male, mean age 11.21 years, off-treatment, attending a regular classroom >50% of the time) participated. PBTS and their primary caregivers (proxy) completed the Social Skills Rating System (SSRS) to assess social competence at baseline, 2, and 8 months follow-up...
April 14, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28405582/telehealth-to-expand-community-health-nurse-education-in-rural-guatemala-a-pilot-feasibility-and-acceptability-evaluation
#6
REVIEW
Kelly A McConnell, Lyndsay K Krisher, Maureen Lenssen, Maya Bunik, Saskia Bunge Montes, Gretchen J Domek
Telehealth education has the potential to serve as an important, low-cost method of expanding healthcare worker education and support, especially in rural settings of low- and middle-income countries. We describe an innovative educational strategy to strengthen a long-term health professional capacity building partnership between Guatemalan and US-based partners. In this pilot evaluation, community health nurses in rural Guatemala received customized, interactive education via telehealth from faculty at the supporting US-based institution...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28397394/parents-and-parenting-with-intellectual-disabilities-an-expanding-field-of-research
#7
EDITORIAL
David McConnell, Maurice Feldman, Marjorie Aunos
No abstract text is available yet for this article.
May 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28387616/long-term-clinical-and-radiographic-outcomes-of-the-prestige-lp-artificial-cervical-disc-replacement-at-2-levels-results-from-a-prospective-randomized-controlled-clinical-trial
#8
Todd H Lanman, J Kenneth Burkus, Randall G Dryer, Matthew F Gornet, Jeffrey McConnell, Scott D Hodges
OBJECTIVE The aim of this study was to assess long-term clinical safety and effectiveness in patients undergoing anterior cervical surgery using the Prestige LP artificial disc replacement (ADR) prosthesis to treat degenerative cervical spine disease at 2 adjacent levels compared with anterior cervical discectomy and fusion (ACDF). METHODS A prospective, randomized, controlled, multicenter FDA-approved clinical trial was conducted at 30 US centers, comparing the low-profile titanium ceramic composite-based Prestige LP ADR (n = 209) at 2 levels with ACDF (n = 188)...
April 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28387213/single-electron-transistors-with-hydrogen-treatment-of-ald-sio-sub-2-sub-in-nanoscale-metal-insulator-metal-tunnel-junctions
#9
Golnaz Karbasian, Michael Steven McConnell, Alexei Orlov, Alexei Nazarov, Gregory Snider
Over the past five years, fabrication of metal-insulator-metal (MIM) single electron transistors (SET) featuring atomic layer deposition (ALD) of ultrathin tunnel barrier dielectrics (SiO<sub>2</sub>, Al<sub>2</sub>O<sub>3</sub>) has been reported. However, the performance of fabricated devices was significantly compromised by the presence of native metal oxide and problems associated with the nucleation of ALD dielectrics on metal substrates. To overcome the difficulty of dielectric ALD nucleation on metal substrates, we recently developed a fabrication technique in which the native metal oxide naturally forming in the presence of the ALD oxidant precursor is first used to promote the nucleation of ALD dielectrics, and then is chemically reduced by forming gas anneal (FGA) at temperatures near 400°C...
April 7, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28376847/performance-of-variable-selection-methods-using-stability-based-selection
#10
Danny Lu, Aalim Weljie, Alexander R de Leon, Yarrow McConnell, Oliver F Bathe, Karen Kopciuk
BACKGROUND: Variable selection is frequently carried out during the analysis of many types of high-dimensional data, including those in metabolomics. This study compared the predictive performance of four variable selection methods using stability-based selection, a new secondary selection method that is implemented in the R package BioMark. Two of these methods were evaluated using the more well-known false discovery rate (FDR) as well. RESULTS: Simulation studies varied factors relevant to biological data studies, with results based on the median values of 200 partial area under the receiver operating characteristic curve...
April 4, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28375598/reassessment-of-the-upper-fremont-glacier-ice-core-chronologies-by-synchronizing-of-ice-core-water-isotopes-to-a-nearby-tree-ring-chronology
#11
Nathan Chellman, Joseph R McConnell, Monica Arienzo, Gregory T Pederson, Sarah M Aarons, Adam Csank
The Upper Fremont Glacier (UFG), Wyoming, is one of the few continental glaciers in the contiguous United States known to preserve environmental and climate records spanning recent centuries. A pair of ice cores taken from UFG have been studied extensively to document changes in climate and industrial pollution (most notably, mid-19th century increases in mercury pollution). Fundamental to these studies is the chronology used to map ice-core depth to age. Here, we present a revised chronology for the UFG ice cores based on new measurements and using a novel dating approach of synchronizing continuous water isotope measurements to a nearby tree-ring chronology...
April 4, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28373890/restructuring-reward-mechanisms-in-nicotine-addiction-a-pilot-fmri-study-of-mindfulness-oriented-recovery-enhancement-for-cigarette-smokers
#12
B Froeliger, A R Mathew, P A McConnell, C Eichberg, M E Saladin, M J Carpenter, E L Garland
The primary goal of this pilot feasibility study was to examine the effects of Mindfulness-Oriented Recovery Enhancement (MORE), a behavioral treatment grounded in dual-process models derived from cognitive science, on frontostriatal reward processes among cigarette smokers. Healthy adult (N = 13; mean (SD) age 49 ± 12.2) smokers provided informed consent to participate in a 10-week study testing MORE versus a comparison group (CG). All participants underwent two fMRI scans: pre-tx and after 8-weeks of MORE...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28371890/type-of-e-cigarette-device-used-among-adolescents-and-young-adults-findings-from-a-pooled-analysis-of-8-studies-of-2-166-vapers
#13
Jessica L Barrington-Trimis, Laura A Gibson, Bonnie Halpern-Felsher, Melissa B Harrell, Grace Kong, Suchitra Krishnan-Sarin, Adam M Leventhal, Alexandra Loukas, Rob McConnell, Scott R Weaver
Background: A recent study of adult smokers who vape found that disposable/cigalike electronic (e-) cigarette devices were more commonly used than later generation devices. However, whether these trends reflect patterns among adolescents and young adults, many of whom have limited or no history of combustible cigarette use, has not been studied. Methods: Participants were drawn from 8 locally, regionally, and U.S. nationally representative studies. Surveys took place between Fall 2014 and Spring 2016; participants were residents of California (3 studies), Texas (2 studies), Connecticut (1 study), or randomly selected from the United States population (2 studies)...
March 22, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28368525/menstrual-cycle-hormone-changes-in-women-traversing-the-menopause-study-of-women-s-health-across-the-nation
#14
Nanette Santoro, Sybil L Crawford, Samar R El Khoudary, Amanda A Allshouse, Sherri-Ann Burnett-Bowie, Joel Finkelstein, Carol Derby, Karen Matthews, Howard M Kravitz, Sioban D Harlow, Gail A Greendale, Ellen B Gold, Rasa Kazlauskaite, Dan McConnell, Genevieve Neal-Perry, Jelena Pavlovic, John Randolph, Gerson Weiss, Hsiang-Yu Chen, Bill Lasley
Context: Menstrual cycle hormone patterns in women approaching menopause are inadequately studied. Objective: To describe day-to-day menstrual cycle hormones in women as they approach menopause from the Study of Women's Health Across the Nation (SWAN) Daily Hormone Study (DHS). Design: DHS enrollees collected daily urine for one entire menstrual cycle or up to 50 days, whichever came first, annually, up to the final menstrual period (FMP) or for up to 10 years...
March 22, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28368520/risk-of-thyroid-nodules-in-residents-of-belarus-exposed-to-chernobyl-fallout-as-children-and-adolescents
#15
Elizabeth K Cahoon, Eldar A Nadirov, Olga N Polanskaya, Vasilina V Yauseyenka, Ilya V Velalkin, Tamara I Yeudachkova, Tamara I Maskvicheva, Victor F Minenko, Wayne Liu, Vladimir Drozdovitch, Kiyohoko Mabuchi, Mark P Little, Lydia B Zablotska, Robert J McConnell, Maureen Hatch, Kamau O Peters, Alexander V Rozhko, Alina V Brenner
Context: Although radiation exposure is an important predictor of thyroid cancer upon diagnosis of a thyroid nodule, the relationship between childhood radiation exposure and thyroid nodules has not been comprehensively evaluated. Objective: To examine the association between internal I-131 thyroid radiation dose and thyroid nodules in young adults exposed during childhood. Design, setting, and participants: In this cross-sectional study, we screened 11,970 residents of Belarus aged ≤18 years at the time of the Chernobyl nuclear accident (April 1986) for thyroid disease (median age 21 years) with thyroid palpation, ultrasonography, blood and urine analysis, and medical follow-up when appropriate...
March 22, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28362549/cd8-t-cell-mediated-anti-malaria-protection-induced-by-malaria-vaccines-assessment-of-hepatic-cd8-t-cells-by-scbc-assay
#16
Jing Zhou, Alaina Kaiser, Colin Ng, Rachel Karcher, Tim McConnell, Patrick Paczkowski, Cristina Fernandez, Min Zhang, Sean Mackay, Moriya Tsuji
Malaria is a severe infectious disease with relatively high mortality, thus having been a scourge of humanity. There are a few candidate malaria vaccines that have shown a protective efficacy in humans against malaria. One of the candidate human malaria vaccines, which is based on human malaria sporozoites and called PfSPZ Vaccine, has been shown to protect a significant proportion of vaccine recipients from getting malaria. PfSPZ Vaccine elicits a potent response of hepatic CD8+ T cells that are specific for malaria antigens in non-human primates...
March 31, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28356179/upper-airway-reflexes-are-preserved-during-dexmedetomidine-sedation-in-children-with-down-syndrome-and-obstructive-sleep-apnea
#17
Mohamed Mahmoud, Stacey L Ishman, Keith McConnell, Robert Fleck, Sally Shott, Goutham Mylavarapu, Ephraim Gutmark, Yuanshu Zou, Rhonda Szczesniak, Raouf S Amin
STUDY OBJECTIVES: The assessment of pharyngeal collapsibility is difficult to perform in children under normal sleep. An alternative is to perform the assessment under an anesthetic, such as dexmedetomidine (DEX), that induces non-rapid eye movement (NREM) sleep. The objectives of this study were to compare critical closing airway pressure (Pcrit) obtained during natural sleep to that obtained under DEX in patients with Down syndrome (DS) and persistent obstructive sleep apnea (OSA) and determine whether Pcrit measured under sedation predicts the severity of OSA...
February 20, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28321198/the-vivid-present-visualization-abilities-are-associated-with-steep-discounting-of-future-rewards
#18
Trishala Parthasarathi, Mairead H McConnell, Jeffrey Luery, Joseph W Kable
Humans and other animals discount the value of future rewards, a phenomenon known as delay discounting. Individuals vary widely in the extent to which they discount future rewards, and these tendencies have been associated with important life outcomes. Recent studies have demonstrated that imagining the future reduces subsequent discounting behavior, but no research to date has examined whether a similar principle applies at the trait level, and whether training visualization changes discounting. The current study examined if individual differences in visualization abilities are linked to individual differences in discounting and whether practicing visualization can change discounting behaviors in a lasting way...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28304237/cervical-disc-arthroplasty-with-the-prestige-lp-disc-versus-anterior-cervical-discectomy-and-fusion-at-2-levels-results-of-a-prospective-multicenter-randomized-controlled-clinical-trial-at-24-months
#19
Matthew F Gornet, Todd H Lanman, J Kenneth Burkus, Scott D Hodges, Jeffrey R McConnell, Randall F Dryer, Anne G Copay, Hui Nian, Frank E Harrell
OBJECTIVE The authors compared the efficacy and safety of arthroplasty using the Prestige LP cervical disc with those of anterior cervical discectomy and fusion (ACDF) for the treatment of degenerative disc disease (DDD) at 2 adjacent levels. METHODS Patients from 30 investigational sites were randomized to 1 of 2 groups: investigational patients (209) underwent arthroplasty using a Prestige LP artificial disc, and control patients (188) underwent ACDF with a cortical ring allograft and anterior cervical plate...
March 17, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28303884/corrigendum-nuclear-rna-seq-of-single-neurons-reveals-molecular-signatures-of-activation
#20
Benjamin Lacar, Sara B Linker, Baptiste N Jaeger, Suguna Rani Krishnaswami, Jerika J Barron, Martijn J E Kelder, Sarah L Parylak, Apuã C M Paquola, Pratap Venepally, Mark Novotny, Carolyn O'Connor, Conor Fitzpatrick, Jennifer A Erwin, Jonathan Y Hsu, David Husband, Michael J McConnell, Roger Lasken, Fred H Gage
No abstract text is available yet for this article.
March 17, 2017: Nature Communications
keyword
keyword
91944
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"