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Respiratory adults and paediatric

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https://www.readbyqxmd.com/read/27889360/validation-of-the-exhaled-breath-temperature-measure-reference-values-in-healthy-subjects
#1
Giovanna E Carpagnano, Maria P Foschino-Barbaro, Corrado Crocetta, Donato Lacedonia, Valerio Saliani, Luigi Davide Zoppo, Peter J Barnes
BACKGROUND: Exhaled breath temperature (EBT) is a new non-invasive method for the study of inflammatory respiratory diseases with a potential to reach clinical practice. However, few studies, and mainly derived from small, paediatric populations, are available on the validation of the method and the range of normal values is not well established. The aim of this study was to measure EBT values in an Italian population of 298 (45.2±15.5 yrs, 143 male, FEV1 97.2±5.8%, FVC 98.4±3.9%) selected from 867 adult volunteers, in order to define reference values in healthy subjects and to analyse the influence of individual and external variables on this parameter...
November 23, 2016: Chest
https://www.readbyqxmd.com/read/27774707/bocavirus-infection-following-paediatric-liver-transplantation
#2
M Y Tan, L N Tan, M M Aw, S H Quak, S V Karthik
HBoV is an emergent virus, which is frequently detected as a co-infective agent. However, it can cause disease on its own. It is associated with respiratory and diarrhoeal illness in children and adults, whether immunocompetent or immunocompromised. We report HBoV infection in a child post-liver transplantation, who presented with persistent fever and mild tachypnea, 3 weeks after a successful transplant. She recovered spontaneously with no graft dysfunction.
October 23, 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/27767331/medical-conditions-associated-with-the-use-of-ct-in-children-and-young-adults-great-britain-1995-2008
#3
Neige M Journy, Kieran McHugh, Richard W Harbron, Mark S Pearce, Amy Berrington de Gonzalez
OBJECTIVE: To describe medical conditions associated with the use of CT in children or young adults with no previous cancer diagnosis. METHODS: Radiologists' reports for scans performed in 1995-2008 in patients <22 years of age were collected from the Radiology Information System in 44 hospitals of Great Britain. By semantic search, an automated procedure identified 192 medical conditions within the radiologists' reports. Manual validation of a subsample by a paediatric radiologist showed a satisfactory performance of the automatic coding procedure...
October 21, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27743767/cystic-fibrosis-comparison-between-patients-in-paediatric-and-adult-age
#4
V Santos, A V Cardoso, C Lopes, P Azevedo, F Gamboa, A Amorim
: Cystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians. Although most cases are diagnosed in childhood, diagnosis in adults is apparently increasing. OBJECTIVE: Evaluate the adult population with CF, comparing patients who were diagnosed before and after 18 years of age. METHODS: Retrospective analysis of patients followed in three main medical centres in Portugal in 2012. Comparison of two groups: G1 - patients diagnosed at <18 years and G2 - patients diagnosed at ≥18 years...
October 13, 2016: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/27666650/asthma-transition-from-childhood-into-adulthood
#5
Oliver Fuchs, Thomas Bahmer, Klaus F Rabe, Erika von Mutius
Asthma is the most prevalent chronic respiratory disease both in children and adults and resembles a complex syndrome rather than a single disease. Different methods have been developed to better characterise distinct asthma phenotypes in childhood and adulthood. In studies of adults, most phenotyping relies on biomaterials from the lower airways; however, this information is missing in paediatric studies because of restricted accessibility. Few patients show symptoms throughout childhood, adolescence, and adulthood...
September 22, 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27649636/an-international-survey-the-role-of-specialist-nurses-in-adult-respiratory-extracorporeal-membrane-oxygenation
#6
Kathleen Jr Daly, Luigi Camporota, Nicholas A Barrett
BACKGROUND: The last decade has seen an increase in the number of centres able to provide venovenous extracorporeal membrane oxygenation (VV-ECMO) internationally across different health care systems. To support this growth, a variety of staffing arrangements have been adopted depending on local need and availability of resources, both in terms of manpower and finances to safely meet the complex needs of the patient and circuit management. AIM: The aim of the survey was to describe current staffing arrangements of care provision for adult patients on VV-ECMO, with a focus on understanding the professional roles and responsibilities of staff managing the circuit in order to inform further discussion around different approaches to staffing...
September 21, 2016: Nursing in Critical Care
https://www.readbyqxmd.com/read/27637414/the-european-survey-on-adverse-systemic-reactions-in-allergen-immunotherapy-eassi-a-paediatric-assessment
#7
Pablo Rodríguez Del Río, Carmen Vidal, Jocelyne Just, Ana I Tabar, Inmaculada Sanchez-Machin, Peter Eberle, Jesus Borja, Petra Bubel, Oliver Pfaar, Pascal Demoly, Moises A Calderón
BACKGROUND: Safety data on "real-life" allergen immunotherapy (AIT) in children and adolescents is usually extrapolated from studies in adults. METHODS: Patients aged 18 or under initiating aeroallergen AIT were evaluated in a prospective European survey. Patient profiles and systemic reactions (SRs) were recorded. Descriptive, univariate and multivariate analyses were used to identify risk factors for SRs. RESULTS: A total of 1,563 patients (mean±SD age: 11...
September 17, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27629557/singing-as-an-adjunct-therapy-for-children-and-adults-with-cystic-fibrosis
#8
J Yoon Irons, Peter Petocz, Dianna Theadora Kenny, Anne B Chang
BACKGROUND: Cystic fibrosis is a genetically inherited, life-threatening condition that affects major organs. The management of cystic fibrosis involves a multi-faceted daily treatment regimen that includes airway clearance techniques, pancreatic enzymes and other medications. Previous studies have found that compliance with this intensive treatment is poor, especially among adolescents. Because of both the nature and consequences of the illness and the relentless demands of the treatment, many individuals with cystic fibrosis have a poor quality of life...
September 15, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27585545/intratidal-recruitment-derecruitment-persists-at-low-and-moderate-positive-end-expiratory-pressure-in-paediatric-patients
#9
Steffen Wirth, Lisa Artner, Tobias Broß, Sara Lozano-Zahonero, Johannes Spaeth, Stefan Schumann
In paediatric patients positive end-expiratory pressure (PEEP) is traditionally set lower than in adults. We investigated whether moderately higher PEEP improves respiratory mechanics and regional ventilation. Therefore, 40 children were mechanically ventilated with PEEP 2 and 5 cmH2O. Volume-dependent compliance profiles were analysed as a measure of intratidal recruitment/derecruitment. Regional ventilation was assessed using electrical impedance tomography. Mean compliance was 17.9±9.9 mL·cmH2O(-1) (PEEP 2 cmH2O), and 19...
August 29, 2016: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27540215/inhaler-counselling-the-real-deal-or-just-fresh-air
#10
Richard Goodwin, Tiranvir Chander, Neha Shah, Steve Tomlin
AIM: To evaluate whether healthcare professionals within the local community are able to counsel paediatric patients on the essential steps required for drug delivery with multi-dose inhalers (MDI), MDIs with a spacer and turbohalers. METHOD: An expert panel produced and piloted checklists for essential and good practice counselling steps. Eligible participants included healthcare professionals regularly counselling children on inhaler devices, including doctors, nurses and pharmacy team members...
September 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27459853/rapidly-progressive-kaposi-s-sarcoma-in-an-iraqi-boy-received-valproic-acid-a-case-report-and-review-of-literature
#11
Lika'a Fasih Y Al-Kzayer, Peter Keizer, Farah T Abdulraheem, Kenji Sano, Minoru Kamata, Kazuo Sakashita, Laith A Y Habbaba, Kenichi Koike
BACKGROUND: Kaposi's sarcoma (KS), an endothelial neoplasm, is associated with human herpes virus (HHV) -8 infection. KS has four clinical sub-types: Mediterranean/classic, African/endemic, human immunodeficiency virus (HIV) -associated/epidemic, and transplantation-related/iatrogenic. Immunosuppression is an important cofactor in KS process. Classic KS (CKS) is exceedingly rare in children and when occurs, it is much more disseminated than adults. The epidemic, HIV-associated and the iatrogenic forms of childhood KS are a result of a profound and acquired T-cell deficiency...
2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27424228/cystic-fibrosis-in-children-and-adults-supplement-to-paediatric-respiratory-reviews
#12
EDITORIAL
T J David
No abstract text is available yet for this article.
August 2016: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27417307/impact-of-environmental-tobacco-smoke-exposure-on-anaesthetic-and-surgical-outcomes-in-children-a-systematic-review-and-meta-analysis
#13
Christopher Chiswell, Yasmin Akram
BACKGROUND: Tobacco smoke exposure in adults is linked to adverse anaesthetic and surgical outcomes. Environmental tobacco smoke (ETS) exposure, including passive smoking, causes a number of known harms in children, but there is no established evidence review on its impact on intraoperative and postoperative outcomes. OBJECTIVES: To undertake a systematic review of the impact of ETS on the paediatric surgical pathway and to establish if there is evidence of anaesthetic, intraoperative and postoperative harm...
July 14, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27405336/high-flow-nasal-cannula-in-children-a-literature-review
#14
REVIEW
Ingvild Bruun Mikalsen, Peter Davis, Knut Øymar
High flow nasal cannula (HFNC) is a relatively new non-invasive ventilation therapy that seems to be well tolerated in children. Recently a marked increase in the use of HFNC has been seen both in paediatric and adult care settings. The aim of this study was to review the current knowledge of HFNC regarding mechanisms of action, safety, clinical effects and tolerance in children beyond the newborn period.We performed a systematic search of the databases PubMed, Medline, EMBASE and Cochrane up to 12th of May 2016...
2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/27272563/increased-versus-stable-doses-of-inhaled-corticosteroids-for-exacerbations-of-chronic-asthma-in-adults-and-children
#15
REVIEW
Kayleigh M Kew, Michael Quinn, Bradley S Quon, Francine M Ducharme
BACKGROUND: People with asthma may experience exacerbations or "attacks" during which their symptoms worsen and additional treatment is required. Written action plans may advocate doubling the dose of inhaled steroids in the early stages of an asthma exacerbation to reduce the severity of the attack and to prevent the need for oral steroids or hospital admission. OBJECTIVES: To compare the clinical effectiveness and safety of increased versus stable doses of inhaled corticosteroids (ICS) as part of a patient-initiated action plan for home management of exacerbations in children and adults with persistent asthma...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27262609/obstructive-sleep-apnoea-children-are-not-little-adults
#16
Haya S Alsubie, Ahmed S BaHammam
During a child's development, several important developmental physiological sleep processes occur, and, occasionally, pathological disorders occur, which results in differences between obstructive sleep apnoea (OSA) in adults and children. There are major differences in sleep and respiratory physiology as well as OSA symptoms and treatment options between children and adults. Many practitioners do not realize these differences, which results in delays in the diagnosis and treatment of OSA in children. The treatment options for OSA in children are markedly different compared with adults, effective in most children...
April 21, 2016: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27255332/cardiac-injury-biomarkers-in-paediatric-age-are-we-there-yet
#17
Ana L Neves, Tiago Henriques-Coelho, Adelino Leite-Moreira, José C Areias
The aim of this article is to evaluate the clinical utility of cardiac injury biomarkers in paediatric age. In December 2015, a literature search was performed (PubMed access to MEDLINE citations; http://www.ncbi.nlm.nih.gov/PubMed/ ). The search strategy included the following medical subject headings and text terms for the key words: "cardiac injury biomarkers", "creatine kinase-MB", "myoglobin", "troponin", "children", "neonate/s", "newborn/s", "infant/s" and echocardiography. In the paediatric population, troponins show a good correlation with the extent of myocardial damage following cardiac surgery and cardiotoxic medication and can be used as predictors of subsequent cardiac recovery and mortality...
November 2016: Heart Failure Reviews
https://www.readbyqxmd.com/read/27118355/non-invasive-ventilation-in-paediatric-critical-care
#18
Sarah L Morley
Non-invasive ventilation (NIV) is a well recognised and increasingly prevalent intervention in the paediatric critical care setting. In the acute setting NIV is used to provide respiratory support in a flexible manner that avoids a requirement for endotracheal intubation or tracheostomy, with the aim of avoiding the complications of invasive ventilation. This article will explore the physiological benefits, complications and epidemiology of the different modes of NIV including continuous positive airway pressure (CPAP), non-invasive positive pressure ventilation (NIPPV) and high-flow nasal cannula oxygen (HFNC)...
March 14, 2016: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27090393/assessing-the-feasibility-of-a-web-based-registry-for-multiple-orphan-lung-diseases-the-australasian-registry-network-for-orphan-lung-disease-arnold-experience
#19
K Casamento, A Laverty, M Wilsher, J Twiss, E Gabbay, I Glaspole, A Jaffe
BACKGROUND: We investigated the feasibility of using an online registry to provide prevalence data for multiple orphan lung diseases in Australia and New Zealand. METHODS: A web-based registry, The Australasian Registry Network of Orphan Lung Diseases (ARNOLD) was developed based on the existing British Paediatric Orphan Lung Disease Registry. All adult and paediatric respiratory physicians who were members of the Thoracic Society of Australia and New Zealand in Australia and New Zealand were sent regular emails between July 2009 and June 2014 requesting information on patients they had seen with any of 30 rare lung diseases...
2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27022699/-resuscitation-cardiopulmonary-resuscitation-in-infants-and-children-paediatric-life-support
#20
Christoph Eich, Bernd Landsleitner
In children, severe emergencies and cardiorespiratory arrests in particular are relatively rare but time-critical events. As compared to adults, hypoxic arrests caused by respiratory disorders that may subsequently result in pulseless electrical activity or asystole are more prevalent. The current Paediatric Life Support (PLS) Guidelines 2015 of the European Resuscitation Council (ERC) acknowledge both limited scientific evidence and aspects of practicability. They also take into account the rather limitedpaediatric routine that most providers have as well as national and local infrastructural differences...
March 2016: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
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