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Respiratory adults and paediatric

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https://www.readbyqxmd.com/read/28523136/phenotypic-presentation-of-chronic-cough-in-children
#1
EDITORIAL
Ahmad Kantar
Chronic cough in children is increasingly defined as a cough that lasts more than four weeks. It is recognized as a different entity than cough in adults. As a result, the diagnostic approach and management of chronic cough in children are no longer extrapolated from adult guidelines. These differences are attributed to the various characteristics of the respiratory tract, immunological system and nervous system in children. Specific paediatric guidelines and algorithms for chronic cough are now widely applied...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28522352/immune-plasma-for-the-treatment-of-severe-influenza-an-open-label-multicentre-phase-2-randomised-study
#2
John H Beigel, Pablo Tebas, Marie-Carmelle Elie-Turenne, Ednan Bajwa, Todd E Bell, Charles B Cairns, Shmuel Shoham, Jaime G Deville, Eric Feucht, Judith Feinberg, Thomas Luke, Kanakatte Raviprakash, Janine Danko, Dorothy O'Neil, Julia A Metcalf, Karen King, Timothy H Burgess, Evgenia Aga, H Clifford Lane, Michael D Hughes, Richard T Davey
BACKGROUND: Influenza causes substantial morbidity and mortality despite available treatments. Anecdotal reports suggest that plasma with high antibody titres to influenza might be of benefit in the treatment of severe influenza. METHODS: In this randomised, open-label, multicentre, phase 2 trial, 29 academic medical centres in the USA assessed the safety and efficacy of anti-influenza plasma with haemagglutination inhibition antibody titres of 1:80 or more to the infecting strain...
May 15, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28512388/insufficient-humidification-of-respiratory-gases-in-patients-who-are-undergoing-therapeutic-hypothermia-at-a-paediatric-and-adult-intensive-care-unit
#3
Yukari Tanaka, Sachiko Iwata, Masahiro Kinoshita, Kennosuke Tsuda, Shoichiro Tanaka, Naoko Hara, Ryota Shindou, Eimei Harada, Ryouji Kijima, Osamu Yamaga, Hitoe Ohkuma, Kazuo Ushijima, Teruo Sakamoto, Yushiro Yamashita, Osuke Iwata
For cooled newborn infants, humidifier settings for normothermic condition provide excessive gas humidity because absolute humidity at saturation is temperature-dependent. To assess humidification of respiratory gases in patients who underwent moderate therapeutic hypothermia at a paediatric/adult intensive care unit, 6 patients were studied over 9 times. Three humidifier settings, 37-default (chamber-outlet, 37°C; Y-piece, 40°C), 33.5-theoretical (chamber-outlet, 33.5°C; Y-piece, 36.5°C), and 33.5-adjusted (optimised setting to achieve saturated vapour at 33...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/28484313/management-of-cardiac-involvement-in-muscular-dystrophies-paediatric-versus-adult-forms
#4
REVIEW
Alberto Palladino, Paola D'Ambrosio, Andrea Antonio Papa, Roberta Petillo, Chiara Orsini, Marianna Scutifero, Gerardo Nigro, Luisa Politano
Muscular dystrophies are a group of genetic disorders characterized by muscle degeneration and consequent substitution by fat and fibrous tissue. Cardiac involvement is an almost constant feature in a great part of these diseases, as both primary myocardial involvement and secondary involvement due to respiratory insufficiency, pulmonary hypertension or reduced mobility. Primary myocardial involvement usually begins more precociously compared to the secondary involvement. In fact the first signs of cardiomyopathy can be observed in the first decade of life in muscular dystrophies with childhood onset and later in adult form of muscular dystrophies as myotonic dystrophy type 1...
December 2016: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
https://www.readbyqxmd.com/read/28462830/a-systematic-review-of-the-impact-of-nurse-initiated-medications-in-the-emergency-department
#5
REVIEW
C J Cabilan, Mary Boyde
BACKGROUND: Nurse-initiated medications are one of the most important strategies used to facilitate timely care for people who present to Emergency Departments (EDs). The purpose of this paper was to systematically review the evidence of nurse-initiated medications to guide future practice and research. METHODS: A systematic review of the literature was conducted to locate published studies and Grey literature. All studies were assessed independently by two independent reviewers for relevance using titles and abstracts, eligibility dictated by the inclusion criteria, and methodological quality...
April 24, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/28249938/remifentanil-for-procedural-sedation-a-systematic-review-of-the-literature
#6
Magdalena Kisilewicz, Hans Rosenberg, Christian Vaillancourt
OBJECTIVE: We sought to determine the performance characteristics of remifentanil as an agent of procedural sedation and analgesia (PSA) for adult and paediatric patients undergoing procedures similar to those executed in the ED. METHODS: We systematically reviewed electronically published literature, grey literature, conference proceedings and trial registries from 1946 to 2015. Outcome measures included PSA effectiveness, recovery time, patient safety and resource management...
May 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28220227/prediction-of-pediatric-sepsis-mortality-within-1%C3%A2-h-of-intensive-care-admission
#7
Luregn J Schlapbach, Graeme MacLaren, Marino Festa, Janet Alexander, Simon Erickson, John Beca, Anthony Slater, Andreas Schibler, David Pilcher, Johnny Millar, Lahn Straney
PURPOSE: The definitions of sepsis and septic shock have recently been revised in adults, but contemporary data are needed to inform similar approaches in children. METHODS: Multicenter cohort study including children <16 years admitted with sepsis or septic shock to ICUs in Australia and New Zealand in the period 2012-2015. We assessed septic shock criteria at ICU admission to define sepsis severity, using 30-day mortality as outcome. Through multivariable logistic regression, a pediatric sepsis score was derived using variables available within 60 min of ICU admission...
February 20, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28210317/summer-schools-of-adult-and-paediatric%C3%A2-respiratory-medicine-course%C3%A2-report
#8
EDITORIAL
Ildiko Horvath, Gabor Kovacs, Oxana Munteanu, Vladyslava Kmyta, Fabio Midulla, Shashank Kadam, Nisreen Rumman
ERS hosted summer schools on adult and paediatric respiratory medicine in Lisbon, Portugalhttp://ow.ly/qcas304C5tO.
December 2016: Breathe
https://www.readbyqxmd.com/read/28209107/gastro-intestinal-manifestations-in-cystic-fibrosis-patients
#9
REVIEW
S Van Biervliet, C de Clercq, D Declercq, E Van Braeckel, S Van Daele, F De Baets, D De Looze
Cystic fibrosis (CF) is a life-limiting disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). This defective chloride channel, present in different organ systems such as respiratory system, gastrointestinal tract, reproductive system and sweat glands, disturbs the ion and water transport over the membranes leading to the well known CF symptoms. CF has outgrown paediatric care, as half of CF patients are currently adults. The CF gastrointestinal tract has its own particularities...
September 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/28153465/prevention-and-treatment-of-skin-lesions-associated-with-non-invasive-mechanical-ventilation-recommendations-of-experts
#10
M Raurell-Torredà, A Romero-Collado, M Rodríguez-Palma, M Farrés-Tarafa, J D Martí, B Hurtado-Pardos, L Peñarrubia-San Florencio, P Saez-Paredes, A M Esquinas
INTRODUCTION: In the last two decades, non-invasive mechanical ventilation (NIV) has been consolidated as an initial strategy for the management of respiratory failure in critical adult and paediatric patients. OBJECTIVES: To identify risk factors and preventive strategies to reduce the incidence of skin lesions associated with clinical devices (LESADIC) related to NIV, as well as the most effective treatment for injuries that cannot be avoided. METHODOLOGY: Review in the MEDLINE, CINAHL and Cochrane databases of studies published in the last 10years to reach consensus through an expert panel...
January 2017: Enfermería Intensiva
https://www.readbyqxmd.com/read/28062684/sale-of-antibiotics-without-a-prescription-at-community-pharmacies-in-urban-china-a-multicentre-cross-sectional-survey
#11
Jie Chang, Dan Ye, Bing Lv, Minghuan Jiang, Shan Zhu, Kangkang Yan, Yun Tian, Yu Fang
Objectives: To quantify sales of antibiotics without a medical prescription and to assess the quality of pharmacy services in relation to the antibiotics sold in community pharmacies in urban China. Methods: A multicentre cross-sectional survey of community pharmacies was undertaken in 2015 using the simulated client method. Two clinical case scenarios (paediatric diarrhoea and adult acute upper respiratory infection) were presented at systematically sampled community pharmacies in Eastern (Nanjing), Central (Changsha) and Western China (Xi'an)...
April 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28032947/controversies-in-the-management-of-caustic-ingestion-injury-an-evidence-based-review
#12
J H Bird, S Kumar, C Paul, J D Ramsden
BACKGROUND: Caustic ingestion of acid or alkaline substances can cause damage to the upper respiratory and upper digestive tract. Initial presentation following caustic ingestion can include oropharyngeal pain, dysphagia and stridor. It is due to this clinical presentation that the resident otolaryngologist is consulted to review and examine these patients to assess for airway compromise and commence initial management and care until airway concern has passed. OBJECTIVE OF REVIEW: This review aims to provide evidence-based guidance in the management of those presenting with acute ingestion injury so that informed initial medical therapy can be commenced and appropriate investigations are arranged to optimize patient outcome...
June 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27889360/validation-of-the-exhaled-breath-temperature-measure-reference-values-in-healthy-subjects
#13
Giovanna E Carpagnano, Maria P Foschino-Barbaro, Corrado Crocetta, Donato Lacedonia, Valerio Saliani, Luigi Davide Zoppo, Peter J Barnes
BACKGROUND: Exhaled breath temperature (EBT) is a new noninvasive method for the study of inflammatory respiratory diseases with a potential to reach clinical practice. However, few studies are available regarding the validation of this method, and they were mainly derived from small, pediatric populations; thus, the range of normal values is not well established. The aim of this study was to measure EBT values in an Italian population of 298 subjects (mean age, 45.2 ± 15.5 years; 143 male subjects; FEV1, 97...
April 2017: Chest
https://www.readbyqxmd.com/read/27774707/bocavirus-infection-following-paediatric-liver-transplantation
#14
M Y Tan, L N Tan, M M Aw, S H Quak, S V Karthik
HBoV is an emergent virus, which is frequently detected as a co-infective agent. However, it can cause disease on its own. It is associated with respiratory and diarrhoeal illness in children and adults, whether immunocompetent or immunocompromised. We report HBoV infection in a child post-liver transplantation, who presented with persistent fever and mild tachypnea, 3 weeks after a successful transplant. She recovered spontaneously with no graft dysfunction.
February 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/27767331/medical-conditions-associated-with-the-use-of-ct-in-children-and-young-adults-great-britain-1995-2008
#15
Neige M Journy, Kieran McHugh, Richard W Harbron, Mark S Pearce, Amy Berrington De Gonzalez
OBJECTIVE: To describe the medical conditions associated with the use of CT in children or young adults with no previous cancer diagnosis. METHODS: Radiologist reports for scans performed in 1995-2008 in non-cancer patients less than 22 years of age were collected from the radiology information system in 44 hospitals of Great Britain. By semantic search, an automated procedure identified 185 medical conditions within the radiologist reports. Manual validation of a subsample by a paediatric radiologist showed a satisfactory performance of the automatic coding procedure...
December 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27743767/cystic-fibrosis-comparison-between-patients-in-paediatric-and-adult-age
#16
V Santos, A V Cardoso, C Lopes, P Azevedo, F Gamboa, A Amorim
Cystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians. Although most cases are diagnosed in childhood, diagnosis in adults is apparently increasing. OBJECTIVE: Evaluate the adult population with CF, comparing patients who were diagnosed before and after 18 years of age. METHODS: Retrospective analysis of patients followed in three main medical centres in Portugal in 2012. Comparison of two groups: G1 - patients diagnosed at <18 years and G2 - patients diagnosed at ≥18 years...
October 13, 2016: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/27666650/asthma-transition-from-childhood-into-adulthood
#17
REVIEW
Oliver Fuchs, Thomas Bahmer, Klaus F Rabe, Erika von Mutius
Asthma is the most prevalent chronic respiratory disease both in children and adults and resembles a complex syndrome rather than a single disease. Different methods have been developed to better characterise distinct asthma phenotypes in childhood and adulthood. In studies of adults, most phenotyping relies on biomaterials from the lower airways; however, this information is missing in paediatric studies because of restricted accessibility. Few patients show symptoms throughout childhood, adolescence, and adulthood...
September 22, 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27649636/an-international-survey-the-role-of-specialist-nurses-in-adult-respiratory-extracorporeal-membrane-oxygenation
#18
Kathleen Jr Daly, Luigi Camporota, Nicholas A Barrett
BACKGROUND: The last decade has seen an increase in the number of centres able to provide venovenous extracorporeal membrane oxygenation (VV-ECMO) internationally across different health care systems. To support this growth, a variety of staffing arrangements have been adopted depending on local need and availability of resources, both in terms of manpower and finances to safely meet the complex needs of the patient and circuit management. AIM: The aim of the survey was to describe current staffing arrangements of care provision for adult patients on VV-ECMO, with a focus on understanding the professional roles and responsibilities of staff managing the circuit in order to inform further discussion around different approaches to staffing...
September 21, 2016: Nursing in Critical Care
https://www.readbyqxmd.com/read/27637414/the-european-survey-on-adverse-systemic-reactions-in-allergen-immunotherapy-eassi-a-paediatric-assessment
#19
Pablo Rodríguez Del Río, Carmen Vidal, Jocelyne Just, Ana I Tabar, Inmaculada Sanchez-Machin, Peter Eberle, Jesus Borja, Petra Bubel, Oliver Pfaar, Pascal Demoly, Moises A Calderón
BACKGROUND: Safety data on 'real-life' allergen immunotherapy (AIT) in children and adolescents is usually extrapolated from studies in adults. METHODS: Patients aged 18 or under initiating aeroallergen AIT were evaluated in a prospective European survey. Patient profiles and systemic reactions (SRs) were recorded. Descriptive, univariate and multivariate analyses were used to identify risk factors for SRs. RESULTS: A total of 1563 patients (mean ± SD age: 11...
February 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27629557/singing-as-an-adjunct-therapy-for-children-and-adults-with-cystic-fibrosis
#20
J Yoon Irons, Peter Petocz, Dianna Theadora Kenny, Anne B Chang
BACKGROUND: Cystic fibrosis is a genetically inherited, life-threatening condition that affects major organs. The management of cystic fibrosis involves a multi-faceted daily treatment regimen that includes airway clearance techniques, pancreatic enzymes and other medications. Previous studies have found that compliance with this intensive treatment is poor, especially among adolescents. Because of both the nature and consequences of the illness and the relentless demands of the treatment, many individuals with cystic fibrosis have a poor quality of life...
September 15, 2016: Cochrane Database of Systematic Reviews
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