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Cardiometabolic Syndrome

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https://www.readbyqxmd.com/read/27903520/visceral-adiposity-and-metabolic-syndrome-after-very-high-fat-and-low-fat-isocaloric-diets-a-randomized-controlled-trial
#1
Vivian L Veum, Johnny Laupsa-Borge, Øyvin Eng, Espen Rostrup, Terje H Larsen, Jan Erik Nordrehaug, Ottar K Nygård, Jørn V Sagen, Oddrun A Gudbrandsen, Simon N Dankel, Gunnar Mellgren
BACKGROUND: Different aspects of dietary pattern, including macronutrient and food profiles, may affect visceral fat mass and metabolic syndrome. OBJECTIVE: We hypothesized that consuming energy primarily from carbohydrate or fat in diets with similar food profiles would differentially affect the ability to reverse visceral adiposity and metabolic syndrome. DESIGN: Forty-six men (aged 30-50 y) with body mass index (in kg/m(2)) >29 and waist circumference >98 cm were randomly assigned to a very high-fat, low-carbohydrate (VHFLC; 73% of energy fat and 10% of energy carbohydrate) or low-fat, high-carbohydrate (LFHC; 30% of energy fat and 53% of energy carbohydrate) diet for 12 wk...
November 30, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27895666/cardiometabolic-risk-in-hyperlipidemic-men-and-women
#2
Michael Leutner, Christian Göbl, Alice Wielandner, Eleonora Howorka, Marlies Prünner, Latife Bozkurt, Jürgen Harreiter, Helmut Prosch, Oliver Schlager, Silvia Charwat-Resl, Alexandra Kautzky-Willer
Objective. The aim of this study was to evaluate sex specific differences of metabolic and clinical characteristics of treated hyperlipidemic men and women (HL-men and HL-women). Methods. In this study vascular and metabolic characteristics of 35 HL-women and 64 HL-men were assessed. In addition a sex specific analysis of metabolic and nutritional habits of HL-patients with prediabetes (HL-IGR) was done. Results. HL-women were older and had favourable concentrations of high density lipoprotein cholesterol (HDL-cholesterol), triglycerides (TG), and triglyceride/HDL-cholesterol ratio (TG/HDL-ratio) but were also shown to have higher concentrations of lipoprotein-a compared to HL-men...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/27863522/cardiometabolic-health-prescribed-antipsychotics-and-health-related-quality-of-life-in-people-with-schizophrenia-spectrum-disorders-a-cross-sectional-study
#3
Daniel Bressington, Jolene Mui, Mei Ling Tse, Richard Gray, Eric F C Cheung, Wai Tong Chien
BACKGROUND: People with schizophrenia-spectrum disorders (SSD) often have high levels of obesity and poor cardiometabolic health. Certain types of antipsychotics have been shown to contribute towards weight gain and there is some equivocal evidence that obesity is related to poor health-related quality of life (HRQoL) in people with SSD. It is also still uncertain if antipsychotic polypharmacy/higher doses of antipsychotics are linked with HRQoL and/or increased risk of obesity/Cardiovascular Disease (CVD)...
November 18, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27856930/effects-of-thyroid-hormone-withdrawal-on-metabolic-and-cardiovascular-parameters-during-radioactive-iodine-therapy-in-differentiated-thyroid-cancer
#4
Jee Hyun An, Kee-Ho Song, Dong-Lim Kim, Suk Kyeong Kim
OBJECTIVE: To investigate the cardiometabolic effects of a severe hypothyroid state induced by withdrawal of thyroid hormone replacement before radioactive iodine therapy. METHODS: Patients with thyroid cancer who were scheduled to receive radioactive iodine ablation were enrolled. Cardiometabolic parameters were measured using blood samples taken immediately before levothyroxine withdrawal, 4 weeks following withdrawal (on radiotherapy day), and 4 weeks following reinstitution of levothyroxine...
November 17, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27842995/antim%C3%A3-llerian-hormone-levels-and-cardiometabolic-risk-in-young-women-with-polycystic-ovary-syndrome
#5
Rebecca A Feldman, Kathleen O'Neill, Samantha F Butts, Anuja Dokras
OBJECTIVE: To determine the association between antimüllerian hormone (AMH) levels and metabolic syndrome (MetSyn) in young women with polycystic ovary syndrome (PCOS). DESIGN: Cross-sectional study. SETTING: Academic PCOS center. PATIENT(S): A total of 252 women aged 18-46 years with PCOS. INTERVENTION: None. MAIN OUTCOME MEASURE(S): Association of AMH with markers of cardiometabolic risk and MetSyn...
November 11, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27834291/sex-differences-in-the-metabolic-dysfunction-and-insulin-resistance-of-skeletal-muscle-glucose-transport-following-high-fructose-ingestion
#6
Yupaporn Rattanavichit, Natsasi Chukijrungroat, Vitoon Saengsirisuwan
The role of high fructose ingestion (HFI) in the development of conditions mimicking human metabolic syndrome has mostly been demonstrated in male animals; however, the extent of HFI-induced metabolic alterations in females remains unclear. The present study investigated whether HFI-induced metabolic perturbations differ between sexes and whether HFI aggravates the metabolic disturbances under ovarian hormone deprivation. Male, female and ovariectomized (OVX) Sprague-Dawley rats were given either water or liquid fructose (10% w/v) for 6 weeks...
November 9, 2016: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/27824688/gross-motor-skills-and-cardiometabolic-risk-in-children-a-mediation-analysis
#7
Ryan D Burns, Timothy A Brusseau, You Fu, James C Hannon
PURPOSE: The purpose of this study was to examine the linear relationship between gross motor skills and cardiometabolic risk, with aerobic fitness as a mediator variable, in low-income children from the U.S. METHODS: Participants were a convenience sample of 224 children (Mean age = 9.1 ± 1.1 years; 129 girls, 95 boys) recruited from five low-income elementary schools from the Mountain West Region of the U.S. Gross motor skills were assessed using the Test for Gross Motor Development 3rd Edition...
November 7, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27817838/noncontraceptive-use-of-oral-combined-hormonal-contraceptives-in-polycystic-ovary-syndrome-risks-versus-benefits
#8
REVIEW
Anuja Dokras
The use of steroid sex hormones for noncontraceptive benefits has been endorsed by several medical societies. In women with polycystic ovary syndrome (PCOS), hormonal contraceptives are first-line therapy for concurrent treatment of menstrual irregularity, acne, and hirsutism. The association of PCOS with obesity, diabetes, and dyslipidemia frequently brings up the debate regarding risks versus benefits of hormonal contraceptives in this population. In women with PCOS, the lack of large-scale studies evaluating the risks with varying doses of ethinyl estradiol, types of progestins, and presence of confounding factors such as obesity, smoking, and other cardiometabolic comorbidities is a significant limitation in these deliberations...
November 3, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27802097/effects-of-oxandrolone-on-cardiometabolic-health-in-boys-with-klinefelter-syndrome-a-randomized-controlled-trial
#9
Shanlee M Davis, Matthew Cox-Martin, Martha Bardsley, Karen Kowal, Philip S Zeitler, Judith L Ross
CONTEXT: Klinefelter syndrome (KS) is a common condition in males resulting in androgen deficiency and cardiometabolic diseases. These conditions are likely related and may be present in pre-pubertal boys with KS. OBJECTIVE: To determine if supplemental low-dose androgen has a beneficial effect on body composition and other cardiometabolic risk factors in pre-pubertal boys with KS. DESIGN, SETTING AND PARTICIPANTS: Secondary analysis of a randomized, double-blind, placebo-controlled clinical trial of oxandrolone between 2007 and 2011 at an academic referral center...
November 1, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27798054/associations-between-cardiorespiratory-fitness-and-the-metabolic-syndrome-in-british-men
#10
Lee Ingle, Michelle Mellis, David Brodie, Gavin R Sandercock
BACKGROUND: Age and body mass index (BMI) are positively associated with the development of the metabolic syndrome (MetS). Cardiorespiratory fitness (CRF) can attenuate BMI-related increases in prevalence of MetS, but the nature of this association across different age strata has not been fully investigated. AIM: To identify the association between CRF and MetS prevalence across age strata (20-69 years) and determine whether associations are independent of BMI...
October 25, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27797929/childhood-socioeconomic-status-in-predicting-metabolic-syndrome-and-glucose-abnormalities-in-adulthood-the-cardiovascular-risk-in-young-finns-study
#11
Elina Puolakka, Katja Pahkala, Tomi T Laitinen, Costan G Magnussen, Nina Hutri-Kähönen, Päivi Tossavainen, Eero Jokinen, Matthew A Sabin, Tomi Laitinen, Marko Elovainio, Laura Pulkki-Råback, Jorma S A Viikari, Olli T Raitakari, Markus Juonala
OBJECTIVE: We prospectively examined whether family socioeconomic status (SES) in childhood is associated with metabolic syndrome (MetS), impaired fasting glucose (IFG), or type 2 diabetes in adulthood. RESEARCH DESIGN AND METHODS: The sample comprised 2,250 participants from the longitudinal Cardiovascular Risk in Young Finns Study cohort. Participants were 3-18 years old at baseline (mean age 10.6 years), and they were followed for 31 years. SES was characterized as reported annual income of the family and classified on an 8-point scale...
October 18, 2016: Diabetes Care
https://www.readbyqxmd.com/read/27777695/association-of-ghrelin-with-cardiometabolic-risk-factors-in-iranian-adolescents-the-caspian-iii-study
#12
Ramin Heshmat, Gita Shafiee, Mostafa Qorbani, Fatemeh Azizi-Soleiman, Shirin Djalalinia, Mohammad Esmaeil Motlagh, Gelayol Ardalan, Zeinab Ahadi, Omid Safari, Saeid Safiri, Roya Kelishadi
Introduction: Current evidence suggests that ghrelin could contribute to the development of metabolic syndrome (MetS) in adults, but limited experience exists in adolescents. This study aims to explore the association of ghrelin levels with the MetS components among Iranian adolescents. Methods: In this case-control study, 32 adolescents with MetS and 148 healthy controls were selected randomly from the childhood and Adolescence Surveillance and Prevention of Adult Non communicable disease (CASPIAN-III) study...
2016: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/27766800/cardiometabolic-risk-factors-in-acute-coronary-syndrome-with-special-reference-to-non-hdl-cholesterol
#13
Debjani S Goswami, Tanuja P Manohar
INTRODUCTION: Cardiovascular diseases are becoming the major cause of morbidity and mortality in most of the developing countries including India. Cardiometabolic risk factors play a vital role in causation of coronary artery disease. Present study was carried out to investigate the role of various risk factors in the occurrence of coronary artery disease (CAD) in population from Central India. SETTING AND DESIGN: This was a hospital-based age and sex matched case-control study, carried out at Lata Mangeshkar Hospital, Nagpur...
October 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27759996/association-between-sarcopenic-obesity-and-cardiovascular-risk-where-are-we
#14
Maria Helena Gusmao-Sena, Karine Curvello-Silva, Jairza Maria Barreto-Medeiros, Carla Hilário Da-Cunha-Daltro
INTRODUCTION: The main changes in the body composition refer to the increase of adipose tissue and/or the decrease of muscular mass, and these changes have effect in many clinical outcomes. Sarcopenic obesity (SO) consists of the presence of excessive adipose tissue and deficit of muscular mass simultaneously. People with SO may have synergistic effect due to obesity and sarcopenia, with increases cardiovascular risk more than obesity itself. OBJECTIVE: To describe the findings in the literature about the association between SO and risk factors and/or cardiometabolic disease (CMD) or cardiovascular disease (CVD)...
September 20, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27754019/js-ksh-jsh-chl-01-2-hypertension-additional-makers-and-mortality-in-subjects-with-metabolic-syndrome-big-data-analysis
#15
Ki Chul Sung
Metabolic syndrome (MetS) is a clustering of cardiometabolic risk factors linked to insulin resistance and visceral obesity. Since 1988, when Gerald Reaven first described MetS as "Syndrome X," an abundance of research has been undertaken on its pathophysiology, prognosis, implications, therapeutic strategies, and clinical relationships with other metabolic diseases. Experts have focused on MetS during the last few decades not only because of the increasing importance of obesity in the development of metabolic diseases but also because of the effect of MetS on mortality and the development of cardiovascular diseases...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753992/ed-05-4-natriuretic-peptides-metabolic-syndrome-and-hypertension-an-integrated-view
#16
Riccardo Sarzani
Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are the cardiac natriuretic peptides (NP), true "cardiometabolic" hormones well known for their renal, endocrine and cardiovascular activities leading to reduced sodium reabsorption and arterial blood pressure. These effects are mainly mediated by the second messenger cGMP that also stimulates lipolysis, mitochondriogenesis and a thermogenic program with potency similar to catecholamines. Two distinct NP receptors modulate the final response to cardiac NP: the cGMP-signaling receptor NPRA and the clearance receptor NPRC...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753812/ssa-04-3-leptin-adiponectin-in-cardiometabolic-disease
#17
Patricio Lopez-Jaramillo
Cardiovascular diseases (CVD) are major causes of death and illness worldwide. In recent decades an increased prevalence of CVD mortality has been reported in low-medium income countries, which has been associated with changes in life styles, deficiencies in health systems and the persistence of social inequities.The metabolic syndrome comprises a cluster of cardiometabolic risk factors, with insulin resistance and increased adiposity as its central features. Identifying individuals with metabolic syndrome is important due to its association with an increased risk of coronary heart disease and type 2 diabetes mellitus (DM2)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27749927/correction-metabolic-and-body-composition-risk-factors-associated-with-metabolic-syndrome-in-a-cohort-of-women-with-a-high-prevalence-of-cardiometabolic-disease
#18
(no author information available yet)
[This corrects the article DOI: 10.1371/journal.pone.0162247.].
2016: PloS One
https://www.readbyqxmd.com/read/27740885/waist-to-height-ratio-compared-to-standard-obesity-measures-as-predictor-of-cardiometabolic-risk-factors-in-asian-indians-in-north-india
#19
Naval K Vikram, Ahmad Nawid Latifi, Anoop Misra, Kalpana Luthra, Surya Prakash Bhatt, Randeep Guleria, Ravindra M Pandey
OBJECTIVE: The aim of this study was to compare the discriminatory ability of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) in identifying the presence of cardiometabolic risk factors in Asian Indians. METHODS: This cross-sectional study involved 509 subjects (278 males and 231 females) aged 20-60 years from New Delhi, India. Measurements included complete clinical examination, blood pressure, weight, height, WC, BMI, WHR and WHtR, fasting blood glucose, lipid profile, and fasting insulin levels...
October 14, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27734684/-are-the-thyroid-hormones-and-thyrotropin-associated-with-cardiometabolic-risks-and-insulin-resistance-even-in-euthyroid-subjects
#20
Vojtěch Hainer, Hana Zamrazilová, Irena Aldhoon Hainerová
Associations of both hypothyroidism and subclinical hypothyroidism with metabolic syndrome are well established. Nowadays, more attention has been paid to the role of thyroid hormones and thyrotropin (TSH) within the euthyroid range on the development of cardiometabolic health risks. The paper summarizes current knowledge related to the associations of lower free thyroxine (fT4) level and higher levels of both free triiodothyronine (fT3) and TSH with body adiposity, metabolic syndrome and insulin resistance in euthyroid subjects...
2016: Vnitr̆ní Lékar̆ství
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