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Cardiometabolic Syndrome

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https://www.readbyqxmd.com/read/28527165/twelve-commandments-to-prevent-tsunami-of-cardiometabolic-syndrome-in-india-by-2025
#1
Ramchandra Lele
No abstract text is available yet for this article.
April 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28526006/cardiometabolic-profile-of-obese-children-in-a-sub-saharan-african-setting-a-cross-sectional-study
#2
Eunice Chedjou-Nono, Suzanne Sap, Simeon-Pierre Choukem, Issa Ngosso Tetanye, Daniel Nebongo, Olivier Koki Ndombo
BACKGROUND: Cardiovascular and metabolic consequences of obesity in children, unlike adults, are still not well understood nor have they been subject to extensive research in Africa. We aimed to identify the cardio-metabolic complications associated with childhood obesity at the early phase of the management of obese children in a reference center in Cameroon. METHODS: In this cross-sectional study conducted from November 2013 to September 2014 and based on World Health Organization (WHO) classification of Obesity (BMI > 3SD under 5 years and BMI > 2SD from 5 and above), we included children aged 3 to 17 years who were being followed up for obesity at the pediatric endocrinology unit of the Mother and Child Center of the Chantal BIYA Foundation in Yaounde, Cameroon...
May 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28521334/lifestyle-recommendations-for-the-prevention-and-management-of-metabolic-syndrome-an-international-panel-recommendation
#3
Pablo Pérez-Martínez, Dimitri P Mikhailidis, Vasilios G Athyros, Mónica Bullo, Patrick Couture, María I Covas, Lawrence de Koning, Javier Delgado-Lista, Andrés Díaz-López, Christian A Drevon, Ramón Estruch, Katherine Esposito, Montserrat Fitó, Marta Garaulet, Dario Giugliano, Antonio García-Ríos, Niki Katsiki, Genovefa Kolovou, Benoît Lamarche, Maria Ida Maiorino, Guillermo Mena-Sánchez, Araceli Muñoz-Garach, Dragana Nikolic, José M Ordovás, Francisco Pérez-Jiménez, Manfredi Rizzo, Jordi Salas-Salvadó, Helmut Schröder, Francisco J Tinahones, Rafael de la Torre, Ben van Ommen, Suzan Wopereis, Emilio Ros, José López-Miranda
The importance of metabolic syndrome (MetS) lies in its associated risk of cardiovascular disease and type 2 diabetes, as well as other harmful conditions such as nonalcoholic fatty liver disease. In this report, the available scientific evidence on the associations between lifestyle changes and MetS and its components is reviewed to derive recommendations for MetS prevention and management. Weight loss through an energy-restricted diet together with increased energy expenditure through physical activity contribute to the prevention and treatment of MetS...
May 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28521179/biological-predictors-of-insulin-resistance-associated-with-posttraumatic-stress-disorder-in-young-military-veterans
#4
Esther M Blessing, Victor Reus, Synthia H Mellon, Owen M Wolkowitz, Janine D Flory, Linda Bierer, Daniel Lindqvist, Firdaus Dhabhar, Meng Li, Meng Qian, Duna Abu-Amara, Isaac Galatzer-Levy, Rachel Yehuda, Charles R Marmar
Posttraumatic stress disorder (PTSD) is associated with increased risk for Type 2 diabetes and cardiovascular disease (cardiometabolic disease), warranting research into targeted prevention strategies. In the present case-control study of 160 young (mean age 32.7 years) male military veterans, we aimed to assess whether PTSD status predicted increased markers of cardiometabolic risk in otherwise healthy individuals, and further, to explore biological pathways between PTSD and these increased markers of cardiometabolic risk...
May 1, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28515160/replacement-of-refined-starches-and-added-sugars-with-egg-protein-and-unsaturated-fats-increases-insulin-sensitivity-and-lowers-triglycerides-in-overweight-or-obese-adults-with-elevated-triglycerides
#5
Kevin C Maki, Orsolya M Palacios, Emily Lindner, Kristin M Nieman, Marjorie Bell, Jennifer Sorce
Background: Hypertriglyceridemia is a common condition in the United States and is often associated with other metabolic disturbances, including insulin resistance, metabolic syndrome, and a predominance of small dense LDL particles.Objective: The objective of this trial was to evaluate the effects of a combination of egg protein (Epro) and unsaturated fatty acids (UFAs) substituted for refined starches and added sugars on insulin sensitivity (primary outcome) and other cardiometabolic health markers in overweight or obese adults with elevated triglyceride (TG) concentrations...
May 17, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28497664/insulin-sensitizers-in-adolescents-with-polycystic-ovary-syndrome
#6
Trang N LE, Edmond P Wickham Iii, John E Nestler
Polycystic ovary syndrome (PCOS) is the most common disorder of androgen excess in women of reproductive age. The diagnosis of PCOS can be more challenging in adolescents than in adult women given significant overlap between normal puberty and the signs of PCOS, including acne, menstrual irregularity, and polycystic ovarian morphology. Optimal treatments for adult women with PCOS vary depending on patient risk factors and reproductive goals, but mainly include hormonal contraception and insulin sensitizers...
May 11, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28493240/does-vitamin-d-status-correlate-with-cardiometabolic-risk-factors-in-adults-with-growth-hormone-deficiency
#7
Ivayla Uzunova, Georgi Kirilov, Sabina Zacharieva, Naydenka Zlatareva, Krasimir Kalinov
Apart from being individually associated with cardiometabolic health, 25(OH)D and IGF-1 interplay with a positive correlation between them, which raises questions about the role of vitamin D for the adverse cardiovascular (CV) risk profile in hyposomatotropism. Thus, we aimed to investigate vitamin D status in GH deficiency (GHD) and the association between 25(OH)D and metabolic syndrome (MetS), its components, and other surrogate markers of CV risk. A total of 129 GHD adults (childhood-onset GHD, 41.9%) underwent blood testing (glucose, insulin, lipid profile, uric acid); blood pressure, anthropometric and bioelectrical-impedance measurements...
May 10, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28483503/gaps-in-knowledge-among-physicians-regarding-diagnostic-criteria-and-management-of-polycystic-ovary-syndrome
#8
Anuja Dokras, Shailly Saini, Melanie Gibson-Helm, Jay Schulkin, Laura Cooney, Helena Teede
OBJECTIVE: To identify gaps in polycystic ovary syndrome (PCOS) knowledge and practice patterns among physicians in North America in response to significant dissatisfaction identified among women with PCOS regarding their diagnosis and treatment experience. DESIGN: Online survey conducted via American College of Obstetrics and Gynecology of gynecologists (ObGyn) and American Society of Reproductive Medicine of reproductive endocrinologists (REI-ObGyn) in 2015-16...
May 5, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28474510/circulating-selenoprotein-p-levels-in-relation-to-mri-derived-body-fat-volumes-liver-fat-content-and-metabolic-disorders
#9
Romina di Giuseppe, Manja Koch, Sabrina Schlesinger, Jan Borggrefe, Marcus Both, Hans-Peter Müller, Jan Kassubek, Gunnar Jacobs, Ute Nöthlings, Wolfgang Lieb
OBJECTIVE: Association studies of selenoprotein P (SELENOP) with cardiometabolic traits in humans are relatively scarce and, in part, conflicting. A general population sample from Northern Germany was evaluated for cross-sectional associations of circulating SELENOP concentrations with metabolic syndrome (MetS), total volumes of MRI-determined visceral (VAT) and subcutaneous (SAT) abdominal adipose tissue, liver signal intensity, and fatty liver disease (FLD). METHODS: Nine hundred and five participants received comprehensive clinical and molecular phenotyping along with measurement of serum SELENOP; 584 individuals received MRI...
May 5, 2017: Obesity
https://www.readbyqxmd.com/read/28474375/angiopoietin-2-and-soluble-tie-2-receptor-plasma-levels-in-children-with-obstructive-sleep-apnea-and-obesity
#10
David Gozal, Abdelnaby Khalyfa, Zhuanghong Qiao, Dale L Smith, Mona F Philby, Dorit Koren, Leila Kheirandish-Gozal
OBJECTIVE: Obstructive sleep apnea (OSA) is a prevalent condition, especially in children with obesity, and is associated with increased risk for metabolic syndrome (MetS). Angiopoietins have been identified as potential biomarkers of endothelial dysfunction and MetS. In adults, angiopoietin-2 (Ang-2) and its soluble receptor (sTie-2) are associated with diabetes, hypertension, and obesity and could be increased in children with OSA and obesity, particularly those with evidence of cardiometabolic alterations...
May 5, 2017: Obesity
https://www.readbyqxmd.com/read/28472106/cardiometabolic-risk-factors-and-health-behaviors-in-family-caregivers
#11
Alyson Ross, Robert Shamburek, Leslie Wehrlen, Stephen D Klagholz, Li Yang, Elyssa Stoops, Sharon L Flynn, Alan T Remaley, Karel Pacak, Nonniekaye Shelburne, Margaret F Bevans
The purpose of this study was to compare components of cardiometabolic risk and health behaviors of 20 family caregivers of allogeneic hematopoietic stem cell transplant patients to those of age, gender, and race/ethnicity-matched controls. A prospective, repeated measures design was used to compare cardiometabolic risk and health behaviors in caregivers and controls at three time-points: pre-transplantation, discharge, and six weeks post-discharge. Measures included components of metabolic syndrome, Reynolds Risk Score, NMR serum lipoprotein particle analyses, and the Health-Promoting Lifestyle Profile II (HPLP-II)...
2017: PloS One
https://www.readbyqxmd.com/read/28464176/breast-feeding-leptin-adiponectin-ratio-and-metabolic-dysfunction-in-adolescents-with-obesity
#12
Nicole L Mihalopoulos, Brittney M Urban, Julie M Metos, Alfred H Balch, Paul C Young, Kristine C Jordan
OBJECTIVES: Increased adiposity increases leptin and decreases adiponectin concentrations, resulting in an increased leptin:adiponectin ratio (LAR). In adults, components of the metabolic syndrome and other cardiometabolic risk factors, what we classify here as "metabolic dysfunction," are associated with both a high LAR and a history of being breast-fed. The relation among breast-feeding, LAR, and degree of metabolic dysfunction in obese youth is unknown. The purpose of our pilot study was to explore this relation and estimate the effect size of the relations to determine the sample size needed to power future prospective studies...
May 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28463859/adiponectin-lipids-and-atherosclerosis
#13
Niki Katsiki, Christos Mantzoros, Dimitri P Mikhailidis
PURPOSE OF REVIEW: Adiponectin is an adipokine with anti-inflammatory, antioxidant, antiatherogenic, pro-angiogenic, vasoprotective and insulin-sensitizing properties. Several factors may influence adiponectin levels, such as genetic polymorphisms, obesity / body fat distribution, diet and exercise as well as cardiovascular risk factors such as sleep deprivation and smoking as well as medications. Adiponectin has been proposed as a potential prognostic biomarker and a therapeutic target in patients with cardiometabolic diseases...
April 29, 2017: Current Opinion in Lipidology
https://www.readbyqxmd.com/read/28457146/are-women-with-polycystic-ovary-syndrome-at-increased-cardiovascular-disease-risk-later-in-life
#14
M N Gunning, B C J M Fauser
To date, the world's leading cause of death amongst women is cardiovascular disease. Polycystic ovary syndrome (PCOS) is associated with an unfavorable cardiometabolic profile in early life. Apart from dyslipidemia, obesity and onset of type 2 diabetes mellitus, androgens are thought to influence cardiovascular health. The question rises whether women with PCOS are truly at risk for cardiovascular disease in later life. In this review paper, we aim to reflect on this assumed relation based on studies in different stages of life in women with PCOS...
April 29, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28451083/prevalence-of-cardio-metabolic-risk-factors-in-a-nationally-representative-sample-of-iranian-adolescents-the-caspian-iii-study
#15
Roya Kelishadi, Ramin Heshmat, Farshad Farzadfar, Mohammad Esmaeil Motlag, Maryam Bahreynian, Saeid Safiri, Gelayol Ardalan, Ehsan Rezaei Darzi, Hamid Asayesh, Fatemeh Rezaei, Mostafa Qorbani
Introduction: The aim of the present study is to explore the prevalence and mean of cardiometabolic risk factors and liver enzymes of Iranian adolescents living in regions with different socioeconomic status (SES). To the best of our knowledge this is the first study reporting these data at sub-national level in Iran. Methods: This multi-centric study was performed in 2009-2010 on a stratified multi-stage probability sample of 5940 students aged 10-18 years, living in urban and rural areas of 27 provinces of Iran...
2017: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/28440767/zinc-alpha-2-glycoprotein-is-overproduced-in-cushing-s-syndrome
#16
Xavier Escoté, Gloria B Aranda, Mireia Mora, Gregori Casals, Joaquim Enseñat, Oscar Vidal, Yaiza Esteban, Irene Halperin, Felicia A Hanzu
INTRODUCTION: Cushing syndrome (CS), an endogenous hypercortisolemic condition with increased cardiometabolic morbidity, leads to development of abdominal obesity, insulin resistance, diabetes and proatherogenic dyslipidemia. Zinc alpha-2 glycoprotein (ZAG) is a recently characterized lipolytic adipokine implicated in regulation of adipose tissue metabolism and fat distribution. In vitro and animal studies suggest that glucocorticoids interact with ZAG secretion and action. To assess the relationship between ZAG and glucocorticoids in a human model of hypercortisolism, circulating ZAG levels were tested in patients with CS and its counterpart controls...
January 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28435445/cardiometabolic-risk-factors-metabolic-syndrome-and-pre-diabetes-in-adolescents-in-the-sierra-region-of-ecuador
#17
Sharon L Casapulla, Cheryl A Howe, Gabriela Rosero Mora, Darlene Berryman, Mario J Grijalva, Edgar W Rojas, Masato Nakazawa, Jay H Shubrook
BACKGROUND: Excess weight (overweight and obesity) is the major modifiable risk factor for type 2 diabetes mellitus (T2DM) and other non-communicable diseases. However, excess weight may not be as predictive of diabetes risk as once thought. While excess weight and other obesity-related non-communicable diseases are of growing concern in low-middle income countries in Latin America, there is limited research on risk factors associated with T2DM in adolescents. This study investigated prevalence of overweight, obesity, prediabetes, diabetes and metabolic syndrome in adolescents in Ecuador...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28420204/fructose-intake-serum-uric-acid-and-cardiometabolic-disorders-a-critical-review
#18
REVIEW
Cristiana Caliceti, Donato Calabria, Aldo Roda, Arrigo F G Cicero
There is a direct relationship between fructose intake and serum levels of uric acid (UA), which is the final product of purine metabolism. Recent preclinical and clinical evidence suggests that chronic hyperuricemia is an independent risk factor for hypertension, metabolic syndrome, and cardiovascular disease. It is probably also an independent risk factor for chronic kidney disease, Type 2 diabetes, and cognitive decline. These relationships have been observed for high serum UA levels (>5.5 mg/dL in women and >6 mg/dL in men), but also for normal to high serum UA levels (5-6 mg/dL)...
April 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28419354/work-organization-sleep-and-metabolic-syndrome-among-long-haul-truck-drivers
#19
M K Lemke, Y Apostolopoulos, A Hege, L Wideman, S Sönmez
Background: The work organization of long-haul truck drivers in the USA contains factors that have been shown to degrade sleep. In combination, these factors generate elevated cardiometabolic risk by inducing components of the metabolic syndrome (MetS). However, the prevalence and severity of MetS and the degree to which such factors differentially influence MetS among these drivers are unknown. Aims: To determine the prevalence and severity of MetS among US long-haul truck drivers and to determine the predictive value of demographic, work organization and sleep variables in MetS diagnosis and severity...
April 17, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/28417301/overview-of-coronary-heart-disease-risk-initiatives-in-south-asia
#20
REVIEW
Ankur Kalra, Deepak L Bhatt, Sanjay Rajagopalan, Kunal Suri, Sundeep Mishra, Romaina Iqbal, Salim S Virani
PURPOSE OF REVIEW: Cardiovascular disease (CVD) is now the leading cause of morbidity and mortality worldwide. Industrialization and economic growth have led to an unprecedented increment in the burden of CVD and their risk factors in less industrialized regions of the world. While there are abundant data on CVD and their risk factors from longitudinal cohort studies done in the West, good-quality data from South Asia are lacking. RECENT FINDINGS: Several multi-institutional, observational, prospective registries, and epidemiologic cohorts in South Asia have been established to systematically evaluate the burden of CVD and their risk factors...
June 2017: Current Atherosclerosis Reports
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