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Cardiometabolic Syndrome

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https://www.readbyqxmd.com/read/28420204/fructose-intake-serum-uric-acid-and-cardiometabolic-disorders-a-critical-review
#1
REVIEW
Cristiana Caliceti, Donato Calabria, Aldo Roda, Arrigo F G Cicero
There is a direct relationship between fructose intake and serum levels of uric acid (UA), which is the final product of purine metabolism. Recent preclinical and clinical evidence suggests that chronic hyperuricemia is an independent risk factor for hypertension, metabolic syndrome, and cardiovascular disease. It is probably also an independent risk factor for chronic kidney disease, Type 2 diabetes, and cognitive decline. These relationships have been observed for high serum UA levels (>5.5 mg/dL in women and >6 mg/dL in men), but also for normal to high serum UA levels (5-6 mg/dL)...
April 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28419354/work-organization-sleep-and-metabolic-syndrome-among-long-haul-truck-drivers
#2
M K Lemke, Y Apostolopoulos, A Hege, L Wideman, S Sönmez
Background: The work organization of long-haul truck drivers in the USA contains factors that have been shown to degrade sleep. In combination, these factors generate elevated cardiometabolic risk by inducing components of the metabolic syndrome (MetS). However, the prevalence and severity of MetS and the degree to which such factors differentially influence MetS among these drivers are unknown. Aims: To determine the prevalence and severity of MetS among US long-haul truck drivers and to determine the predictive value of demographic, work organization and sleep variables in MetS diagnosis and severity...
April 17, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/28417301/overview-of-coronary-heart-disease-risk-initiatives-in-south-asia
#3
REVIEW
Ankur Kalra, Deepak L Bhatt, Sanjay Rajagopalan, Kunal Suri, Sundeep Mishra, Romaina Iqbal, Salim S Virani
PURPOSE OF REVIEW: Cardiovascular disease (CVD) is now the leading cause of morbidity and mortality worldwide. Industrialization and economic growth have led to an unprecedented increment in the burden of CVD and their risk factors in less industrialized regions of the world. While there are abundant data on CVD and their risk factors from longitudinal cohort studies done in the West, good-quality data from South Asia are lacking. RECENT FINDINGS: Several multi-institutional, observational, prospective registries, and epidemiologic cohorts in South Asia have been established to systematically evaluate the burden of CVD and their risk factors...
June 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28409494/association-between-metabolically-healthy-central-obesity-in-women-and-levels-of-soluble-receptor-for-advanced-glycation-end-products-soluble-vascular-adhesion-protein-1-and-the-activity-of-semicarbazide-sensitive-amine-oxidase
#4
Ivana Koborová, Radana Gurecká, Melinda Csongová, Katarína Volkovová, Éva Szökő, Tamás Tábi, Katarína Šebeková
AIM: To determine the levels of circulating soluble receptor for advanced glycation end products (sRAGE), as a biomarker of risk of metabolic syndrome and cardiovascular disease development in centrally obese (CO) women considered metabolically healthy (COH) in comparison with those metabolically unhealthy (COU). METHODS: 47 lean healthy, 17 COH (presenting waist-to-height ratio ≥0.5 but not elevated blood pressure, atherogenic lipid profile, and insulin resistance), and 50 COU (CO presenting ≥2 risk factors) women aged 40-45 years were included...
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28399838/association-of-nutrition-club-membership-with-markers-of-health-a-cross-sectional-study
#5
Sai Krupa Das, Taylor A Vail, Namibia Lebrón-Torres, Kara A Livingston, Susan B Roberts, Gail T Rogers, Cheryl H Gilhooly, Lorien E Urban, Edward Saltzman, Nicola M McKeown, Sara C Folta
BACKGROUND: Nutrition clubs (NC) operate in community settings and provide members with nutrition education and meal replacements for weight management. NC are owned and operated by distributors of Herbalife products. There are over 6200 NC in the US, but there has been no independent assessment of the association of these NC with biomarkers of health. METHODS: We conducted a cross-sectional pilot study to compare the health status of 100 NC members to 100 community-matched controls (CC) in the greater Boston area...
April 11, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28399005/effects-of-a-6-month-caloric-restriction-induced-weight-loss-program-in-obese-postmenopausal-women-with-and-without-the-metabolic-syndrome-a-monet-study
#6
Ahmed Ghachem, Denis Prud'homme, Rémi Rabasa-Lhoret, Martin Brochu
OBJECTIVE: To compare the effects of a caloric restriction (CR) on body composition, lipid profile, and glucose homeostasis in obese postmenopausal women with and without metabolic syndrome (MetS). METHODS: Secondary analyses were performed on 73 inactive obese postmenopausal women (age 57.7 ± 4.8 years; body mass index 32.4 ± 4.6 kg/m) who participated in the 6-month CR arm of a study of the Montreal-Ottawa New Emerging Team. The harmonized MetS definition was used to categorize participants with MetS (n = 20, 27...
April 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28382218/a-lifestyle-intervention-program-for-successfully-addressing-major-cardiometabolic-risks-in-persons-with-sci-a-three-subject-case-series
#7
Gregory E Bigford, Armando J Mendez, Luisa Betancourt, Patricia Burns-Drecq, Deborah Backus, Mark S Nash
INTRODUCTION: This study is a prospective case series analyzing the effects of a comprehensive lifestyle intervention program in three patients with chronic paraplegia having major risks for the cardiometabolic syndrome (CMS). CASE PRESENTATION: Individuals underwent an intense 6-month program of circuit resistance exercise, nutrition using a Mediterranean diet and behavioral support, followed by a 6-month extension (maintenance) phase involving minimal support...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28378850/intra-abdominal-and-subcutaneous-abdominal-fat-as-predictors-of-cardiometabolic-risk-in-a-sample-of-mexican-children
#8
C González-Álvarez, N Ramos-Ibáñez, J Azprioz-Leehan, L Ortiz-Hernández
BACKGROUND/OBJECTIVE: Few studies in Latin American paediatric populations have differentiated fat deposits in specific areas, such as intra-abdominal fat (IAF) and subcutaneous abdominal fat (SAF). Research in diverse populations is needed, as patterns of fat accumulation vary by ethnicity. The aim of this study was to determine whether IAF and/or SAF are related to cardiometabolic risk factors, independent of total body fat (TBF), in a group of Mexican schoolchildren. SUBJECTS/METHODS: A cross-sectional study was conducted in Mexico City with 94 children aged between 5 and 11 years...
April 5, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28367325/association-between-sleep-habits-and-metabolically-healthy-obesity-in-adults-a-cross-sectional-study
#9
Thirumagal Kanagasabai, Ramandeep Dhanoa, Jennifer L Kuk, Chris I Ardern
Higher body mass index (BMI) increases the risk of cardiometabolic diseases, but nearly a third of the people living with obesity (BMI: ≥30 kg/m(2)) are metabolically healthy (MHO). Extreme sleep durations and poor sleep quality are associated with higher bodyweight and cardiometabolic dysfunction, but the full extent to which sleep habits may help differentiate those with MHO versus metabolically abnormal obesity (MAO) is not yet known. Data from the U.S. National Health and Nutritional Examination Survey 2005-08 was used (BMI: ≥30 kg/m(2); ≥20 y; N = 1,777)...
2017: Journal of Obesity
https://www.readbyqxmd.com/read/28361809/association-of-non-alcoholic-fatty-liver-disease-and-cardiometabolic-risk-factors-with-early-atherosclerosis-in-an-adult-population-in-southern-italy
#10
Carmelo Antonio Caserta, Alfonso Mele, Pasquale Surace, Luigina Ferrigno, Angela Amante, Arianna Messineo, Carmelo Vacalebre, Fulvia Amato, Damiano Baldassarre, Mauro Amato, Fabrizio Marcucci, Massimo Zuin
AIM: The prevalence of risk factors for cardiovascular and metabolic diseases was investigated in an adult population of the city of Cittanova, Southern Italy. METHODS: The study was conducted among 992 randomly selected adults aged 18-75 years, between April 2009 and January 2011. RESULTS: Prevalence rates of non-alcoholic fatty liver disease (NAFLD), overweight, obesity, and metabolic syndrome (MS) were 24.8%, 41.5%, 27.1%, and 34.4%, respectively...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28347564/the-gut-microbiota-metabolism-of-pomegranate-or-walnut-ellagitannins-yields-two-urolithin-metabotypes-that-correlate-with-cardiometabolic-risk-biomarkers-comparison-between-normoweight-overweight-obesity-and-metabolic-syndrome
#11
María V Selma, Antonio González-Sarrías, Jordi Salas-Salvadó, Cristina Andrés-Lacueva, Cesarettin Alasalvar, Asım Örem, Francisco A Tomás-Barberán, Juan C Espín
BACKGROUND & AIMS: Urolithins are microbial metabolites produced after consumption of ellagitannin-containing foods such as pomegranates and walnuts. Parallel to isoflavone-metabolizing phenotypes, ellagitannin-metabolizing phenotypes (urolithin metabotypes A, B and 0; UM-A, UM-B and UM-0, respectively) can vary among individuals depending on their body mass index (BMI), but correlations between urolithin metabotypes (UMs) and cardiometabolic risk (CMR) factors are unexplored. We investigated the association between UMs and CMR factors in individuals with different BMI and health status...
March 16, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28346857/the-influence-of-epicardial-fat-and-nonalcoholic-fatty-liver-disease-on-heart-rate-recovery-in-metabolic-syndrome
#12
Kyoung Im Cho, Eun Ah Jo, Sang Hoon Cho, Bo Hyun Kim
BACKGROUND: Epicardial adipose tissues reflecting visceral fat accumulations of the heart are associated with metabolic syndrome (MetS) and can be a predictor of other cardiometabolic diseases. It can adversely influence autonomic nervous system (ANS) of heart. Heart rate recovery (HRR) is an easy method for measuring ANS dysfunction. The purpose of this study was to determine whether epicardial fat thickness (EFT) and nonalcoholic fatty liver disease (NAFLD) are related to HRR in patients with MetS...
March 27, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28344764/atypical-antipsychotics-recent-research-findings-and-applications-to-clinical-practice-proceedings-of-a-symposium-presented-at-the-29th-annual-european-college-of-neuropsychopharmacology-congress-19-september-2016-vienna-austria
#13
REVIEW
Robin Murray, Christoph U Correll, Gavin P Reynolds, David Taylor
Available evidence suggests that second-generation atypical antipsychotics are broadly similar to first-generation agents in terms of their efficacy, but may have a more favourable tolerability profile, primarily by being less likely to cause extrapyramidal symptoms. However, atypical antipsychotics are variably associated with disturbances in the cardiometabolic arena, including increased body weight and the development of metabolic syndrome, which may reflect differences in their receptor binding profiles...
March 2017: Therapeutic Advances in Psychopharmacology
https://www.readbyqxmd.com/read/28338545/risperidone-and-cardiometabolic-risk-in-children-and-adolescents-clinical-and-instrumental-issues
#14
Emilia Matera, Lucia Margari, Vincenzo Ostilio Palmieri, Giuseppina Zagaria, Roberto Palumbi, Francesco Margari
PURPOSE/BACKGROUND: Although second-generation antipsychotics are used to treat and manage symptoms for several psychiatric disorders, data about their adverse effects in developmental age are limited. The aim of this prospective observational study was to verify the cardiovascular and metabolic risk in a sample of antipsychotic-naive children/adolescent patients starting risperidone therapy. METHODS: Twenty-two patients, younger than 18 years, were recruited. The assessment included anthropometric data, cardiovascular parameters, blood tests, and ultrasonographic abdominal study...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28333713/micrornas-and-lipid-metabolism
#15
Binod Aryal, Abhishek K Singh, Noemi Rotllan, Nathan Price, Carlos Fernández-Hernando
PURPOSE OF REVIEW: Work over the past decade has identified the important role of microRNAs (miRNAS) in regulating lipoprotein metabolism and associated disorders including metabolic syndrome, obesity, and atherosclerosis. This review summarizes the most recent findings in the field, highlighting the contribution of miRNAs in controlling LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) metabolism. RECENT FINDINGS: A number of miRNAs have emerged as important regulators of lipid metabolism, including miR-122 and miR-33...
March 22, 2017: Current Opinion in Lipidology
https://www.readbyqxmd.com/read/28333235/ovarian-hormones-and-obesity
#16
Brigitte Leeners, Nori Geary, Philippe N Tobler, Lori Asarian
BACKGROUND: Obesity is caused by an imbalance between energy intake, i.e. eating and energy expenditure (EE). Severe obesity is more prevalent in women than men worldwide, and obesity pathophysiology and the resultant obesity-related disease risks differ in women and men. The underlying mechanisms are largely unknown. Pre-clinical and clinical research indicate that ovarian hormones may play a major role. OBJECTIVE AND RATIONALE: We systematically reviewed the clinical and pre-clinical literature on the effects of ovarian hormones on the physiology of adipose tissue (AT) and the regulation of AT mass by energy intake and EE...
March 2, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28329079/sleep-duration-and-cardiometabolic-risk-among-chinese-school-aged-children-do-adipokines-play-a-mediating-role
#17
Lujiao Li, Junling Fu, Xin Ting Yu, Ge Li, Lu Xu, Jinghua Yin, Hong Cheng, Dongqing Hou, Xiaoyuan Zhao, Shan Gao, Wenhui Li, Changhong Li, Struan F A Grant, Mingyao Li, Yi Xiao, Jie Mi, Ming Li
Objective: To assess the associations between sleep duration and cardiometabolic risk factors in Chinese school-aged children and to explore the possible mediating role of adipokines. Methods: Sleep duration was collected in 3,166 children from the Beijing Child and Adolescent Metabolic Syndrome study. Glucose homeostasis and other cardiometabolic risk factors were assessed. Serum adipokines including leptin, total and high-molecular-weight (HMW) adiponectin, resistin, fibroblast growth factor 21 (FGF21) and retinol binding protein 4 (RBP4) were determined...
March 9, 2017: Sleep
https://www.readbyqxmd.com/read/28316139/changes-in-body-composition-and-metabolic-profile-during-interleukin-6-inhibition-in-rheumatoid-arthritis
#18
Anne Tournadre, Bruno Pereira, Fréderic Dutheil, Charlotte Giraud, Daniel Courteix, Vincent Sapin, Thomas Frayssac, Sylvain Mathieu, Sandrine Malochet-Guinamand, Martin Soubrier
BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by increased mortality associated with cardiometabolic disorders including dyslipidaemia, insulin resistance, and cachectic obesity. Tumour necrosis factor inhibitors and interleukin 6 receptor blocker licensed for the treatment of RA decrease inflammation and could thus improve cardiovascular risk, but their effects on body composition and metabolic profile need to be clarified. We investigated the effects of tocilizumab (TCZ), a humanized anti-interleukin 6 receptor antibody, on body composition and metabolic profile in patients treated for RA...
March 18, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28304393/the-effects-of-oestrogens-and-their-receptors-on-cardiometabolic-health
#19
REVIEW
Eugenia Morselli, Roberta S Santos, Alfredo Criollo, Michael D Nelson, Biff F Palmer, Deborah J Clegg
Cardiovascular disease (CVD) is one of the leading causes of mortality in developed countries. The incidence of CVD is sexually dimorphic, and research has focused on the contribution of sex steroids to the development and progression of the cardiometabolic syndrome, which is defined as a clustering of interrelated risk factors that promote the development of atherosclerosis (which can lead to CVD) and type 2 diabetes mellitus. Data are inconclusive as to how sex steroids and their respective receptors increase or suppress the risk of developing the cardiometabolic syndrome and thus CVD...
March 17, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28301314/metabolic-syndrome-prevalence-by-race-ethnicity-and-sex-in-the-united-states-national-health-and-nutrition-examination-survey-1988-2012
#20
Justin Xavier Moore, Ninad Chaudhary, Tomi Akinyemiju
INTRODUCTION: Metabolic syndrome is a cluster of cardiometabolic risk factors associated with increased risk of multiple chronic diseases, including cancer and cardiovascular disease. The objectives of this study were to estimate the prevalence of metabolic syndrome overall, by race and sex, and to assess trends in prevalence from 1988 through 2012. METHODS: We analyzed data from the National Health and Nutrition Examination Survey (NHANES) for 1988 through 2012...
March 16, 2017: Preventing Chronic Disease
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