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https://www.readbyqxmd.com/read/29664814/spinal-sagittal-alignment-in-patients-with-dropped-head-syndrome
#1
Kazuma Murata, Endo Kenji, Hidekazu Suzuki, Taichiro Takamatsu, Hirosuke Nishimura, Yuji Matsuoka, Yasunobu Sawaji, Hidetoshi Tanaka, Kengo Yamamoto
STUDY DESIGN: This is a retrospective radiographic study of a consecutive case series of dropped head syndrome (DHS) at a single tertiary referral center. OBJECTIVE: The aim was to clarify the spinal sagittal alignment of DHS. SUMMARY OF BACKGROUND DATA: DHS is characterized by chin-on-chest deformity and devastatingly impedes activities of daily living in affected individuals. Among various forms of DHS, isolated neck extensor myopathy (INEM) is considered to cause the chin-on-chest symptom in the absence of specific abnormality...
April 16, 2018: Spine
https://www.readbyqxmd.com/read/29655451/muscle-specific-tyrosine-kinase-and-myasthenia-gravis-owing-to-other-antibodies
#2
REVIEW
Michael H Rivner, Mamatha Pasnoor, Mazen M Dimachkie, Richard J Barohn, Lin Mei
Around 20% of patients with myasthenia gravis are acetylcholine receptor antibody negative; muscle-specific tyrosine kinase antibodies (MuSK) were identified as the cause of myasthenia gravis in 30% to 40% of these cases. Anti MuSK myasthenia gravis is associated with specific clinical phenotypes. One is a bulbar form with fewer ocular symptoms. Others show an isolated head drop or symptoms indistinguishable from acetylcholine receptor-positive myasthenia gravis. These patients usually respond well to immunosuppressive therapy, but not as well to cholinesterase inhibitors...
May 2018: Neurologic Clinics
https://www.readbyqxmd.com/read/29617484/-trends-and-factors-associated-with-food-insecurity-in-brazil-the-national-household-sample-survey-2004-2009-and-2013
#3
Taíse Gama Dos Santos, Jonas Augusto Cardoso da Silveira, Giovana Longo-Silva, Elyssia Karine Nunes Mendonça Ramires, Risia Cristina Egito de Menezes
The aim of this study was to analyze trends and factors associated with food insecurity in Brazil in 2004, 2009, and 2013, using microdata from the National Household Sample Survey (PNAD). Food insecurity was assessed using the Brazilian Food Insecurity Scale. Independent variables were selected from a conceptual model of determination of food insecurity, which was also used in the elaboration of multiple generalized linear models. The results show a downward trend in food insecurity prevalence from 2004 to 2013, especially for moderate and severe food insecurity, from 17% in 2004 (95%CI: 15...
March 29, 2018: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29617078/complete-supine-percutaneous-nephrolithotomy-with-gopro%C3%A2-ten-steps-for-success
#4
Fabio Carvalho Vicentini, Hugo Daniel Barone Dos Santos, Carlos Alfredo Batagello, Julia Rothe Amundson, Evaristo Peixoto Oliveira, Giovanni Scala Marchini, Miguel Srougi, Willian Carlos Nahas, Eduardo Mazzucchi
OBJECTIVE: To show a video of a complete supine Percutaneous Nephrolithotomy (csPCNL) performed for the treatment of a staghorn calculus, from the surgeon's point of view. The procedure was recorded with a GoPro® camera, demonstrating the ten essential steps for a successful procedure. MATERIALS AND METHODS: The patient was a 38 years-old woman with 2.4cm of left kidney lower pole stone burden who presented with 3 months of lumbar pain and recurrent urinary tract infections...
March 15, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29615290/gait-training-using-a-hybrid-assistive-limb-hal-attenuates-head-drop-a-case-report
#5
Kousei Miura, Masao Koda, Hideki Kadone, Shigeki Kubota, Yukiyo Shimizu, Hiroshi Kumagai, Katsuya Nagashima, Kentaro Mataki, Kengo Fujii, Hiroshi Noguchi, Toru Funayama, Tetsuya Abe, Yoshiyuki Sankai, Masashi Yamazaki
Dropped head syndrome (DHS) is characterized by a chin-on-chest deformity, which can severely interfere with forward vision and impair activities of daily living. A standardized treatment strategy for DHS has not been established. To our knowledge, this is the first case report describing the efficacy of gait training using a hybrid assistive limb (HAL) for DHS. A 75-year-old man showed apparent head drop in a standing position, resulting in passively reducible chin-on-chest deformity. A radiograph image showed apparent cervical kyphosis...
March 31, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29600424/comparison-of-ice-hockey-goaltender-helmets-for-concussion-type-impacts
#6
J Michio Clark, Karen Taylor, Andrew Post, T Blaine Hoshizaki, Michael D Gilchrist
Concussions are among the most common injuries sustained by ice hockey goaltenders and can result from collisions, falls and puck impacts. However, ice hockey goaltender helmet certification standards solely involve drop tests to a rigid surface. This study examined how the design characteristics of different ice hockey goaltender helmets affect head kinematics and brain strain for the three most common impact events associated with concussion for goaltenders. A NOCSAE headform was impacted under conditions representing falls, puck impacts and shoulder collisions while wearing three different types of ice hockey goaltender helmet models...
March 29, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29584492/differences-in-the-protective-capabilities-of-bicycle-helmets-in-real-world-and-standard-specified-impact-scenarios
#7
Megan L Bland, David S Zuby, Becky C Mueller, Steven Rowson
OBJECTIVE: The purpose of this study was to investigate relative differences in impact attenuation capabilities of bicycle helmets under real-world impact conditions and safety standard-specified conditions using a standard rig. METHODS: A Consumer Product Safety Commission (CPSC) test rig was used to impact 10 helmet models of varied design. Impact configurations included 2 locations and 2 velocities. A frontal rim location (inferior to the standard-defined test area) and a temporal location were selected to reflect common cyclist impacts...
February 28, 2018: Traffic Injury Prevention
https://www.readbyqxmd.com/read/29575406/knee-high-compression-socks-minimize-head-up-tilt-induced-cerebral-and-cardiovascular-responses-following-dynamic-exercise
#8
Tristan W Dorey, Myles W O'Brien, Susan A Robinson, Derek S Kimmerly
INTRODUCTION: In healthy individuals during a non-exercised state, knee-high compression socks (CS) may reduce the magnitude of lower limb venous pooling during orthostasis but are not effective at minimizing the incidence of presyncopal symptoms. However, exaggerated reductions in cerebral blood flow velocity (CBV), and cardiac stroke volume (SV) occur during passive head-up tilt (HUT) testing following dynamic exercise. It is unknown if CS can minimize post-exercise HUT-induced decrements in CBV and SV in this population...
March 25, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29562484/foot-drop-caused-by-a-movable-cystic-mass-during-knee-motion
#9
Nack Hwan Kim, Sang-Heon Lee
BACKGROUND: Nerve injury due to a movable cystic mass during knee motion is a rare neuropathy, which can be diagnosed precisely using a dynamic ultrasonogram. OBJECTIVE: To present a case with foot drop and common peroneal neuropathy that involved a movable cystic mass during knee flexion adjacent to the proximal tibiofibular joint. METHODS: Case report. RESULTS: A 47-year-old female was referred to our institute for a right foot drop...
March 9, 2018: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29559647/burst-mode-pumping-a-new-mechanism-of-drinking-in-mosquitoes
#10
Kenji Kikuchi, Mark A Stremler, Souvick Chatterjee, Wah-Keat Lee, Osamu Mochizuki, John J Socha
Mosquitoes transport liquid foods into the body using two muscular pumps in the head. In normal drinking, these pumps reciprocate in a stereotyped pattern of oscillation, with a high frequency but small stroke volume. Do mosquitoes modulate their neuromotor programs for pumping to produce different drinking modes? More broadly, what are the mechanical consequences of a two-pump system in insects? To address these questions, we used synchrotron x-ray imaging and fluid mechanical modeling to investigate drinking performance in mosquitoes...
March 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29550348/use-of-a-case-mix-approach-to-study-the-trends-in-the-incidence-of-second-primary-cancers
#11
Boris Gass, Emilie Marrer, Simona Bara, Karine Ligier, Florence Molinié, Marc Colonna, Laetitia Daubisse-Marliac, Brigitte Trétarre, Bénédicte Lapôtre-Ledoux, Anne-Sophie Woronoff, Anne-Valérie Guizard, Véronique Bouvier, Xavier Troussard, Christian Gaiddon, Delphine Klein, Michel Velten, Jérémie Jégu
PURPOSE: To analyze trends in second primary cancer (SPC) incidence by using a case-mix approach to standardize on first cancer site distribution. METHODS: Cases registered by 13 French cancer registries between 1989 and 2010 and followed-up until June 2013 were included. The person-year approach was used to compute standardized incidence ratios (SIRs) of metachronous SPC. Usual SIRs and cancer site-specific weighted SIRs called "case-mix SIRs" (cmSIRs) were estimated by sex and calendar period of first cancer diagnosis...
February 15, 2018: Annals of Epidemiology
https://www.readbyqxmd.com/read/29531796/two-stage-corrective-surgery-for-severe-rigid-cervical-kyphotic-deformity-with-unilateral-vertebral-artery-occlusion-after-old-blunt-trauma-a-case-report
#12
Tsunehiko Konomi, Kota Suda, Satoko Matsumoto, Miki Komatsu, Masahiko Takahata, Norimasa Iwasaki, Akio Minami
Introduction: There are considerable risks for vertebral artery (VA) injury in case of corrective surgery for a severe and rigid cervical kyphotic deformity. This case report describes a rare case of surgical management for pre-existing traumatic rigid cervical kyphosis associated with unilateral VA occlusion. Case presentation: A 73-year-old male fell down and injured his neck. He was referred to our hospital 10 months after injury because his degree of head drop progressed gradually to a chin-on-chest position such that he could not look straight forward...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29530029/effect-of-clinical-decision-rules-patient-cost-and-malpractice-information-on-clinician-brain-ct-image-ordering-a-randomized-controlled-trial
#13
Ronald W Gimbel, Ronald G Pirrallo, Steven C Lowe, David W Wright, Lu Zhang, Min-Jae Woo, Paul Fontelo, Fang Liu, Zachary Connor
BACKGROUND: The frequency of head computed tomography (CT) imaging for mild head trauma patients has raised safety and cost concerns. Validated clinical decision rules exist in the published literature and on-line sources to guide medical image ordering but are often not used by emergency department (ED) clinicians. Using simulation, we explored whether the presentation of a clinical decision rule (i.e. Canadian CT Head Rule - CCHR), findings from malpractice cases related to clinicians not ordering CT imaging in mild head trauma cases, and estimated patient out-of-pocket cost might influence clinician brain CT ordering...
March 12, 2018: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29529928/in-vitro-susceptibility-of-ciprofloxacin-resistant-methicillin-resistant-staphylococcus-aureus-to-ototopical-therapy
#14
David D Walker, Michael Z David, Dominic Catalano, Robert Daum, Michael B Gluth
Objective Despite the rising incidence of methicillin-resistant Staphylococcus aureus (MRSA) otologic infections, choice of treatment remains controversial. Only fluoroquinolone-containing ototopical preparations are approved by the US Food and Drug Administration for middle ear application. Furthermore, American Academy of Otolaryngology-Head and Neck Surgery Foundation guidelines advocate ototopical monotherapy for both tympanostomy tube otorrhea and acute otitis externa. Unfortunately, MRSA may be ciprofloxacin resistant...
March 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29515922/a-case-of-cushing-s-syndrome-due-to-ectopic-adrenocorticotropic-hormone-secretion-from-esthesioneuroblastoma-with-long-term-follow-up-after-resection
#15
Leslee N Matheny, Sudipa Sarkar, Hanyuan Shi, Jiun-Ruey Hu, Hannah Harmsen, Ty W Abel, Shubhada M Jagasia, Shichun Bao
We present a case of a 52-year-old male who developed Cushing's Syndrome due to ectopic adrenocorticotrophic hormone (ACTH) secretion from a large esthesioneuroblastoma (ENB) of the nasal sinuses. The patient initially presented with polyuria, polydipsia, weakness, and confusion. Computed tomography scan of the head and magnetic resonance imaging showed a 7 cm skull base mass centered in the right cribriform plate without sella involvement. Work-up revealed ACTH-dependent hypercortisolemia, which did not suppress appropriately after high-dose dexamethasone...
2018: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/29511685/a-simple-scatter-reduction-method-in-cone-beam-computed-tomography-for-dental-and-maxillofacial-applications-based-on-monte-carlo-simulation
#16
Chalinee Thanasupsombat, Saowapak S Thongvigitmanee, Sorapong Aootaphao, Pairash Thajchayapong
The quality of images obtained from cone-beam computed tomography (CBCT) is important in diagnosis and treatment planning for dental and maxillofacial applications. However, X-ray scattering inside a human head is one of the main factors that cause a drop in image quality, especially in the CBCT system with a wide-angle cone-beam X-ray source and a large area detector. In this study, the X-ray scattering distribution within a standard head phantom was estimated using the Monte Carlo method based on Geant4. Due to small variation of low-frequency scattering signals, the scattering signals from the head phantom can be represented as the simple predetermined scattering signals from a patient's head and subtracted the projection data for scatter reduction...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29497893/the-importance-of-the-scalp-in-head-impact-kinematics
#17
Antonia Trotta, Dimitris Zouzias, Guido De Bruyne, Aisling Ní Annaidh
The best way to reduce the risk of head injury (up to 69% reduction) is to wear a helmet. In recent years, the improvement of helmet standard tests focused on reproducing realistic impact conditions and including the effect of rotational acceleration. However, less importance has been given to the development of a realistic headform. The goal of this work was to evaluate the role of scalp tissue in head impact kinematics; both with respect to its mechanical properties and with respect to its sliding properties...
March 1, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29491336/-dropped-head-syndrome-as-first-manifestation-of-primary-hyperparathyroid-myopathy
#18
Kiyobumi Ota, Sayo Koseki, Kenji Ikegami, Iichiroh Onishi, Hiyoryuki Tomimitsu, Shuzo Shintani
75 years old woman presented with 6-month history of progressive dropped head syndrome. Neurological examination revealed moderate weakness of flexor and extensor of neck and mild weakness of proximal appendicular muscles with normal deep tendon reflexes. The needle electromyography showed short duration and low amplitude motor unit potential. No fibrillation potentials or positive sharp waves were seen. Biopsy of deltoid muscle was normal. Laboratory studies showed elevated levels of serum calcium (11.8 mg/dl, upper limit of normal 10...
February 28, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29491332/-a-case-of-alexander-disease-with-dropped-head-syndrome
#19
Kentaro Maeda, Katsushige Iwai, Yosuke Kobayashi, Hirotake Tsuji, Tomokatsu Yoshida, Yasushi Kobayashi
A 51-year-old woman presented with progressive weakness of the neck extensor muscles and gait disturbances since the past 6 years. In addition, she presented with symptoms such as dysarthria, dysphagia, bladder, and rectal disturbances. Bilateral plantar reflex was positive. Her gait was short-stepped-spastic. Brain and cervical MRI showed atrophy of the medulla and spinal cord. As these imaging features were suggestive of Alexander disease (AxD), we sequenced the GFAP gene. We identified a heterozygous c.368T>C missense mutation of the GFAP gene in the patient...
February 28, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29491124/effect-of-cariporide-on-ram-sperm-ph-regulation-and-motility-possible-role-of-nhe1
#20
Stefania Muzzachi, Lorenzo Guerra, Nicola Antonio Martino, Maria Favia, Giuseppe Punzi, Fabio Silvestre, Antonio Ciro Guaricci, Maria Teresa Roscino, Ciro Leonardo Pierri, Maria Elena Dell'Aquila, Valeria Casavola, Giovanni Michele Lacalandra, Elena Ciani
Sperm motility, a feature essential for in vivo fertilization, is influenced by intracellular pH (pHi ) homeostasis. Several mechanisms are involved in pHi regulation, among which sodium-hydrogen exchangers (NHEs), a family of integral transmembrane proteins that catalyse the exchange of Na+ for H+ across lipid bilayers. A preliminary characterization of NHE activity and kinetic parameters, followed by analysis of the expression and localization of the protein in ram spermatozoa was performed. NHE activity showed an apparent Km for external Na+ of 17...
February 28, 2018: Reproduction: the Official Journal of the Society for the Study of Fertility
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