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Pharmacist antimicrobial stewardship

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https://www.readbyqxmd.com/read/27919870/hospital-pharmacists-take-time-out-for-antimicrobial-stewardship
#1
Kate Traynor
No abstract text is available yet for this article.
December 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27872355/acceptance-of-pharmacist-driven-antimicrobial-stewardship-recommendations-with-differing-levels-of-physician-involvement-in-a-children-s-hospital
#2
Leah Molloy, Eric McGrath, Ronald Thomas, Keith S Kaye, Michael J Rybak
This prospective interventional study assessed whether a pharmacist-physician team in a setting where physician support is not provided for daily antimicrobial stewardship (AS) activities would improve later acceptance of pharmacist recommendations once multidisciplinary efforts stopped and the pharmacist again worked alone. This was measured by AS recommendation acceptance rate during 3 study phases wherein AS recommendations were provided by a pharmacist alone (Phase 1), a pharmacist and a physician together (Phase 2), and then a pharmacist alone again (Phase 3)...
November 20, 2016: Clinical Pediatrics
https://www.readbyqxmd.com/read/27866945/a-global-call-from-five-countries-to-collaborate-in-antibiotic-stewardship-united-we-succeed-divided-we-might-fail
#3
REVIEW
Debra A Goff, Ravina Kullar, Ellie J C Goldstein, Mark Gilchrist, Dilip Nathwani, Allen C Cheng, Kelly A Cairns, Kevin Escandón-Vargas, Maria Virginia Villegas, Adrian Brink, Dena van den Bergh, Marc Mendelson
In February, 2016, WHO released a report for the development of national action plans to address the threat of antibiotic resistance, the catastrophic consequences of inaction, and the need for antibiotic stewardship. Antibiotic stewardship combined with infection prevention comprises a collaborative, multidisciplinary approach to optimise use of antibiotics. Efforts to mitigate overuse will be unsustainable without learning and coordinating activities globally. In this Personal View, we provide examples of international collaborations to address optimal prescribing, focusing on five countries that have developed different approaches to antibiotic stewardship-the USA, South Africa, Colombia, Australia, and the UK...
November 17, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27803503/evaluation-of-pharmacist-impact-on-culture-review-process-for-patients-discharged-from-the-emergency-department
#4
Ruben D Santiago, Jose A Bazan, Nicole V Brown, Eric J Adkins, Mary Beth Shirk
Background: Accurate and timely review of microbiological test results is a core component of antimicrobial stewardship. There is documented success of these programs in the inpatient setting; however, emergency department (ED) patients are typically not included in these initiatives. Objectives: To assess the impact of an emergency medicine pharmacist (EMP)-facilitated review process of positive microbiological test results from patients discharged from the ED as measured by time to positive result review and number of indicated interventions completed...
October 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27795335/cost-analysis-of-implementing-maldi-tof-plus-real-time-antimicrobial-stewardship-intervention-for-bloodstream-infections
#5
Twisha S Patel, Rola Kaakeh, Jerod L Nagel, Duane W Newton, James G Stevenson
BACKGROUND: Studies evaluating rapid diagnostic testing plus stewardship intervention have consistently demonstrated improved clinical outcomes for patients with bloodstream infections. However, the cost of implementing new rapid diagnostic testing can be significant, and usually does not generate additional revenue. There is minimal data evaluating the financial impact of adding MALDI-TOF for rapid organism identification and dedicating pharmacy stewardship personnel time, on the total hospital costs...
October 19, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27789965/pharmacist-managed-dose-adjustment-feedback-using-therapeutic-drug-monitoring-of-vancomycin-was-useful-for-patients-with-methicillin-resistant-staphylococcus-aureus-infections-a-single-institution-experience
#6
Ryuichi Hirano, Yuichi Sakamoto, Junichi Kitazawa, Shoji Yamamoto, Naoki Tachibana
BACKGROUND: Vancomycin (VCM) requires dose adjustment based on therapeutic drug monitoring. At Aomori Prefectural Central Hospital, physicians carried out VCM therapeutic drug monitoring based on their experience, because pharmacists did not participate in the dose adjustment. We evaluated the impact of an Antimicrobial Stewardship Program (ASP) on attaining target VCM trough concentrations and pharmacokinetics (PK)/pharmacodynamics (PD) parameters in patients with methicillin-resistant Staphylococcus aureus (MRSA) infections...
2016: Infection and Drug Resistance
https://www.readbyqxmd.com/read/27767002/experience-with-rapid-microarray-based-diagnostic-technology-and-antimicrobial-stewardship-for-patients-with-gram-positive-bacteremia
#7
Elizabeth A Neuner, Andrea M Pallotta, Simon W Lam, David Stowe, Steven M Gordon, Gary W Procop, Sandra S Richter
OBJECTIVE To describe the impact of rapid diagnostic microarray technology and antimicrobial stewardship for patients with Gram-positive blood cultures. DESIGN Retrospective pre-intervention/post-intervention study. SETTING A 1,200-bed academic medical center. PATIENTS Inpatients with blood cultures positive for Staphylococcus aureus, Enterococcus faecalis, E. faecium, Streptococcus pneumoniae, S. pyogenes, S. agalactiae, S. anginosus, Streptococcus spp., and Listeria monocytogenes during the 6 months before and after implementation of Verigene Gram-positive blood culture microarray (BC-GP) with an antimicrobial stewardship intervention...
November 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27725066/implementing-an-antimicrobial-stewardship-program
#8
Caren McHenry Martin
The Centers for Medicare & Medicaid Services is expected to expand requirements for antimicrobial stewardship in nursing facilities during 2016. Many facilities are looking to pharmacists to help them take the initial steps toward developing these coordinated programs to promote the appropriate use of antimicrobials.
2016: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/27725011/-esprit-de-corps-towards-collaborative-integration-of-pharmacists-and-nurses-into-antimicrobial-stewardship-programmes-in-south-africa
#9
N Schellack, R Pretorius, A P Messina
With the global threat of antimicrobial resistance now more emergent than ever, there should be wider collaboration between members of the multidisciplinary healthcare team. This article proposes possible ways of engagement between the pharmacist, nurse and doctor. The pharmacist and nurse are placed in an ideal position through united efforts (camaraderie) to redirect healthcare towards improved patient outcomes while also reducing antimicrobial resistance.
September 23, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27686471/targeted-de-escalation-rounds-may-effectively-and-safely-reduce-meropenem-use
#10
U Ni Riain, M Tierney, C Doyle, A Vellinga, C Fleming, M Cormican
OBJECTIVE: Use of meropenem in our hospital has doubled in recent years. An audit in 2013 showed that although initiation of therapy with meropenem was generally appropriate, therapy was rarely subsequently reviewed and de-escalated where appropriate. Therefore, a structured stewardship initiative focussed on meropenem de-escalation was developed. METHODS: A local guideline for review and de-escalation of meropenem was developed and approved by the Antimicrobial Stewardship Team...
September 29, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27667501/pharmacist-engagement-within-a-hepatitis-c-ambulatory-care-clinic-in-the-era-of-a-treatment-revolution
#11
Timothy P Gauthier, Eva Moreira, Chantal Chan, Alexandria Cabrera, Maribel Toro, Mara Z Carrasquillo, Mark Corentin, Elizabeth M Sherman
OBJECTIVES: To describe an innovative hepatitis C virus (HCV) care program and treatment outcomes resulting from pharmacist services. SETTING: Adult ambulatory care HCV clinic within the Miami Veteran Affairs Healthcare System. PRACTICE DESCRIPTION: Pharmacists with limited prescriptive authority are integrated into a medical hepatology care team. PRACTICE INNOVATION: Pharmacists screen patients with HCV infection for treatment eligibility, counsel patients upon treatment initiation, assess ongoing treatment success and toxicity through patient appointments, telephone calls, and the ordering of pertinent laboratory data, and provide oversight of all patients on HCV therapies...
September 22, 2016: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/27592160/effect-of-an-antimicrobial-stewardship-intervention-on-outcomes-for-patients-with-clostridium-difficile-infection
#12
Hanna K Welch, Jerod L Nagel, Twisha S Patel, Tejal N Gandhi, Benrong Chen, John De Leon, Carol E Chenoweth, Laraine L Washer, Krishna Rao, Gregory A Eschenauer
BACKGROUND: Although antimicrobial stewardship programs (ASPs) are uniquely positioned to improve treatment of Clostridium difficile infection (CDI) through targeted interventions, studies to date have not rigorously evaluated the influence of ASP involvement on clinical outcomes attributed to CDI. METHODS: We performed a quasiexperimental study of adult patients with CDI before (n = 307) and after (n = 285) a real-time ASP review was initiated. In the intervention group, an ASP pharmacist was notified of positive CDI results and consulted with the care team to initiate optimal therapy, minimize concomitant antibiotic and acid-suppressive therapy, and recommend surgical/infectious diseases consultation in complicated cases...
December 1, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27571295/education-and-communication-in-an-interprofessional-antimicrobial-stewardship-program
#13
Pamela A Foral, Jennifer M Anthone, Christopher J Destache, Renuga Vivekanandan, Laurel C Preheim, Gary L Gorby, John M Horne, Leo A Dobronski, Javeria J Syed, Cezarina Mindru, Mir A Ali, Karim F Ali, Kari A Neemann, Marvin J Bittner
CONTEXT: Interprofessional education/interprofessional practice (IPE/IPP) is an essential component in medical education and training. A collaborative interprofessional team environment ensures optimal patient-centered care. OBJECTIVE: To describe the implementation of 2 interprofessional antimicrobial stewardship program (ASP) teams using IPE/IPP and to assess the acceptance rate by the primary medical and surgical teams of ASP recommendations for antimicrobial interventions...
September 1, 2016: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/27540225/how-well-do-outpatient-prescriptions-adhere-to-good-antimicrobial-stewardship
#14
Hirminder Ubhi, Mitul Patel, Lisa Ludwig
AIM: Aims of the study included evaluation of outpatient antibiotic prescribing practices relating to good Antimicrobial Stewardship1 focusing on documentation of indication and duration. METHOD: Prescriptions dispensed at the Outpatient Pharmacy over a 6 week were evaluated. Data collected include patient's hospital identification in full, the antibiotic prescribed, duration of treatment, indication (in a specifically allocated area on the prescription) and route of administration, prescriber speciality and grade...
September 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27527526/return-to-sender-the-need-to-re-address-patient-antibiotic-allergy-labels-in-australia-and-new-zealand
#15
J A Trubiano, L J Worth, K Urbancic, T M Brown, D L Paterson, M Lucas, E Phillips
BACKGROUND: Antibiotic allergies are frequently reported and have significant impacts upon appropriate prescribing and clinical outcomes. We surveyed infectious diseases physicians, allergists, clinical immunologists and hospital pharmacists to evaluate antibiotic allergy knowledge and service delivery in Australia and New Zealand. METHODS: An online multi-choice questionnaire was developed and endorsed by representatives of the Australasian Society of Clinical Immunology and Allergy (ASCIA), Australasian Society of Infectious Diseases (ASID) and Society of Hospital Pharmacists Australia (SHPA)...
August 16, 2016: Internal Medicine Journal
https://www.readbyqxmd.com/read/27502752/ten-key-points-for-the-appropriate-use-of-antibiotics-in-hospitalised-patients-a-consensus-from-the-antimicrobial-stewardship-and-resistance-working-groups-of-the-international-society-of-chemotherapy
#16
REVIEW
Gabriel Levy Hara, Souha S Kanj, Leonardo Pagani, Lilian Abbo, Andrea Endimiani, Heiman F L Wertheim, Carlos Amábile-Cuevas, Pierre Tattevin, Shaheen Mehtar, Fernando Lopes Cardoso, Serhat Unal, Ian Gould
The Antibiotic Stewardship and Resistance Working Groups of the International Society for Chemotherapy propose ten key points for the appropriate use of antibiotics in hospital settings. (i) Get appropriate microbiological samples before antibiotic administration and carefully interpret the results: in the absence of clinical signs of infection, colonisation rarely requires antimicrobial treatment. (ii) Avoid the use of antibiotics to 'treat' fever: use them to treat infections, and investigate the root cause of fever prior to starting treatment...
September 2016: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/27457099/current-state-of-antimicrobial-stewardship-at-solid-organ-and-hematopoietic-cell-transplant-centers-in-the-united-states
#17
Susan K Seo, Kaming Lo, Lilian M Abbo
OBJECTIVE To assess the extent of antimicrobial stewardship programs (ASPs) at solid organ transplant (SOT) and hematopoietic cell transplant (HCT) centers in the United States. DESIGN An 18-item voluntary survey was developed to gauge current antimicrobial stewardship practices in transplant patients, examine the availability and perceived usefulness of novel diagnostics and azole levels to guide therapy, and identify challenges for implementation of ASPs at these centers. PARTICIPANTS The survey was distributed electronically to infectious disease physicians and pharmacists at adult and pediatric SOT and HCT centers during May 1-22, 2015...
October 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27450706/impact-of-a-focused-antimicrobial-stewardship-program-in-adherence-to-antibiotic-prophylaxis-and-antimicrobial-consumption-in-appendectomies
#18
Humberto Guanche Garcell, Ariadna Villanueva Arias, Cristobal Pancorbo Sandoval, Moraima E Valle Gamboa, Adan Bode Sado, Ramon N Alfonso Serrano
Antibiotic use in appendectomy constitutes a fundamental practice to achieve the clinical outcomes and the prevention of surgical site infection. A prospective interventional study was performed in a community hospital from January 2013 to December 2015 with the aim of determining the effect of a focused antimicrobial stewardship program in the compliance with antibiotic prophylaxis and the antimicrobial consumption in appendectomies. The compliance with the antibiotic prophylaxis was monitored for the timing of administration, the selection and dose and the discontinuation...
July 19, 2016: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/27349712/impact-of-antimicrobial-stewardship-on-outcomes-in-hospitalized-veterans-with-pneumonia
#19
Kari E Kurtzhalts, John A Sellick, Christine A Ruh, James F Carbo, Michael C Ott, Kari A Mergenhagen
PURPOSE: The purpose of this study was to evaluate the impact of an antimicrobial stewardship program (ASP) on outcomes for inpatients with pneumonia, including length of stay, treatment duration, and 30-day readmission rates. METHODS: A retrospective chart review comparing outcomes of veterans admitted with pneumonia before (2005-2006) and after (2013-2014) implementation of an ASP was conducted; pneumonia was defined according to International Classification of Diseases, Ninth Revision (ICD-9) codes...
July 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27312577/antimicrobial-stewardship-across-47-south-african-hospitals-an-implementation-study
#20
Adrian J Brink, Angeliki P Messina, Charles Feldman, Guy A Richards, Piet J Becker, Debra A Goff, Karri A Bauer, Dilip Nathwani, Dena van den Bergh
BACKGROUND: The available data on antimicrobial stewardship programmes in Africa are scarce. The aims of this study were to assess the implementation of an antimicrobial stewardship programme in a setting with limited infectious disease resources. METHODS: We implemented a pharmacist-driven, prospective audit and feedback strategy for antimicrobial stewardship on the basis of a range of improvement science and behavioural principles across a diverse group of urban and rural private hospitals in South Africa...
September 2016: Lancet Infectious Diseases
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