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https://www.readbyqxmd.com/read/28695764/laryngeal-cysts-in-adults-simplifying-classification-and-management
#1
Richard Heyes, David G Lott
Objective Laryngeal cysts may occur at any mucosa-lined location within the larynx and account for 5% to 10% of nonmalignant laryngeal lesions. A number of proposed classifications for laryngeal cysts exist; however, no previously published classification aims to guide management. This review analyzes contemporary laryngeal cyst management and proposes a framework for the terminology and management of cystic lesions in the larynx. Data Sources PubMed/Medline. Review Methods A primary literature search of the entire Medline database was performed for all titles of publications pertaining to laryngeal cysts and reviewed for relevance...
July 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28676331/the-relationship-between-partial-upper-airway-obstruction-and-inter-breath-transition-period-during-sleep
#2
Dwayne L Mann, Bradley A Edwards, Simon A Joosten, Garun S Hamilton, Shane Landry, Scott A Sands, Stephen J Wilson, Philip I Terrill
Short pauses or "transition-periods" at the end of expiration and prior to subsequent inspiration are commonly observed during sleep in humans. However, the role of transition periods in regulating ventilation during physiological challenges such as partial airway obstruction (PAO) has not been investigated. Twenty-nine obstructive sleep apnea patients and eight controls underwent overnight polysomnography with an epiglottic catheter. Sustained-PAO segments (increased epiglottic pressure over ≥5 breaths without increased peak inspiratory flow) and unobstructed reference segments were manually scored during apnea-free non-REM sleep...
July 1, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28653789/congenital-epiglottic-cyst-neck-position-dependent-respiratory-distress-in-newborns
#3
Kaori Ouchi, Yutaro Onizawa, Takahiro Kido, Atsushi Iwabuchi, Ryo Sumazaki
No abstract text is available yet for this article.
June 27, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28653483/morphology-of-laryngeal-cartilage-of-the-nine-banded-armadillo-dasypus-novemcinctus-linnaeus-1758
#4
Clarisse Maria Barbosa Fonseca, Andrezza Braga Soares da Silva, Maria Michele Araújo de Sousa Cavalcante, Ingrid Macedo de Oliveira, Selma Maria Santos Moura, Bruno Melo Cunha, Carla Maria de Carvalho Leite, Maria Acelina Martins de Carvalho, Waldilleny Ribeiro de Araújo Moura, Márcia Dos Santos Rizzo, Airton Mendes Conde Júnior
Armadillos, Xenarthras representatives, known for adaptability to different ecosystems, own specific morphophysiological characteristics that are not known and deserve to be studied. The aim of this study was to describe the morphology of cartilage of the larynx of the nine-banded armadillo (Dasypus novemcinctus). Five dead armadillos were donated by the Chico Mendes Institute of Biodiversity (ICMBio-PI) to the Federal University of Piauí. The animals were fixed and dissected for removal of the larynx. The cartilages were identified and described, photodocumented, and schematized...
June 27, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28651794/airflow-shape-is-associated-with-the-pharyngeal-structure-causing-obstructive-sleep-apnea
#5
Pedro R Genta, Scott A Sands, James P Butler, Stephen H Loring, Eliot S Katz, B Gail Demko, Eric J Kezirian, David P White, Andrew Wellman
BACKGROUND: Obstructive sleep apnea (OSA) results from the collapse of different pharyngeal structures (soft palate, tongue, lateral walls, epiglottis). The structure involved in collapse has been shown to impact non-CPAP OSA treatment. Different inspiratory airflow shapes are also observed among OSA patients. We hypothesized that inspiratory flow shape reflects the underlying pharyngeal structure involved in airway collapse. METHODS: Subjects with OSA were studied with a pediatric endoscope and simultaneous nasal flow and pharyngeal pressure recordings during natural sleep...
June 23, 2017: Chest
https://www.readbyqxmd.com/read/28647431/temporal-segmentation-for-laryngeal-high-speed-videoendoscopy-in-connected-speech
#6
Maryam Naghibolhosseini, Dimitar D Deliyski, Stephanie R C Zacharias, Alessandro de Alarcon, Robert F Orlikoff
OBJECTIVE: This study proposes a gradient-based method for temporal segmentation of laryngeal high-speed videoendoscopy (HSV) data obtained during connected speech. METHODS: A custom-developed HSV system coupled with a flexible fiberoptic nasolaryngoscope was used to record one vocally normal female participant during reading of the "Rainbow Passage." A gradient-based algorithm was developed to generate a motion window. When applied to the HSV data, the motion window acted as a filter tracking the location of the vibrating vocal folds...
June 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28634151/speech-and-swallowing-abnormalities-in-adults-with-polg-associated-ataxia-polg-a
#7
Adam P Vogel, Natalie Rommel, Andreas Oettinger, Marius Horger, Patrick Krumm, Eva-Maria Kraus, Ludger Schöls, Matthis Synofzik
BACKGROUND: Mutations in the nuclear-encoded mitochondrial DNA polymerase gamma (POLG) can result in a wide spectrum of neurological deficits. A common presentation is progressive ataxia (POLG-A) which includes impaired speech and swallowing. The nature, severity and impact of these deficits in POLG-A is not known. A comprehensive quantitative and qualitative characterization of dysarthria and dysphagia in this recurrent ataxia disorder will assist in diagnostics, provide insights into the underlying pathology, and establish the foundation for future therapy trials...
June 19, 2017: Mitochondrion
https://www.readbyqxmd.com/read/28631160/role-of-imaging-in-the-follow-up-of-t2-t3-glottic-cancer-treated-by-transoral-laser-microsurgery
#8
Filippo Marchi, Cesare Piazza, Marco Ravanelli, Giovanna Gaggero, Giampiero Parrinello, Alberto Paderno, Pietro Perotti, Marta Filauro, Roberto Maroldi, Giorgio Peretti
An unblinded retrospective analysis of prospectively collected data was carried out on 138 patients affected by glottic pT2 and selected pT3 squamous cell carcinomas (SCC) treated by transoral laser microsurgery (TLM). The entire cohort was divided into two groups: Group A included 78 "high-risk" patients (pT2 with impaired vocal cord mobility, pT3 for anterior paraglottic and/or pre-epiglottic space invasion, presence of angioembolization, perineural spread, and positive lymph nodes in the neck) who underwent postoperative surveillance by endoscopy and imaging (CT or MR), while Group B included 60 "low-risk" patients (pT2 with absence of the above-mentioned features) who underwent endoscopic follow-up alone...
June 19, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28630241/multipathogenic-necrotising-supraglottitis-in-an-immunocompetent-patient
#9
Jacob Joseph Ahmed, James Douglas Constable, Tawakir Kamani, Mriganka De
Supraglottitis is a potentially life-threatening condition. It is now uncommon due to the Haemophilus influenzae type B vaccination and is more recently caused by Streptococcus pneumoniae, S. pyogenes, H. influenzae non-type B, H. parainfluenzae, Staphylococcus aureus and Pasteurella multocida Very rarely, it can cause necrotising supraglottitis/epiglottitis, and this has been reported in immunocompromised individuals. We present a unique case of multipathogenic supraglottitis causing laryngeal fibrinoid necrosis in an immunocompetent patient...
June 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28609480/an-automated-and-reliable-method-for-breath-detection-during-variable-mask-pressures-in-awake-and-sleeping-humans
#10
Chinh D Nguyen, Jason Amatoury, Jayne C Carberry, Danny J Eckert
Accurate breath detection is crucial in sleep and respiratory physiology research and in several clinical settings. However, this process is technically challenging due to measurement and physiological artifacts and other factors such as variable leaks in the breathing circuit. Recently developed techniques to quantify the multiple causes of obstructive sleep apnea, require intermittent changes in airway pressure applied to a breathing mask. This presents an additional unique challenge for breath detection...
2017: PloS One
https://www.readbyqxmd.com/read/28585510/reemergence-of-the-natural-history-of-otolaryngologic-infections-lessons-learned-from-2-american-presidents
#11
James Naples, Marissa Schwartz, Marc Eisen
Presidents George Washington and Theodore Roosevelt suffered complications of epiglottitis and otomastoiditis, respectively. The introduction of antibiotics and vaccinations against Haemophilus influenzae and Streptococcus pneumoniae has significantly reduced the incidence of these otolaryngologic infections, such that the natural history of the disease is rarely encountered. However, antibiotic resistance and pathogenic evolution has raised concern about increased virulence of these common organisms. A retrospective evaluation of the complications suffered by Washington and Roosevelt provides valuable insight to the natural history of common otolaryngologic infections that may reemerge as a result of organism evolution in response to antibiotics and vaccines...
May 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28567968/sudden-death-by-spontaneous-epiglottic-hematoma-secondary-to-high-blood-levels-of-warfarin
#12
Séverine Gilard-Pioc, Pascal Guerard, François Paraf, Irène François-Purssell
A 67-year-old man was found dead, at his home. On external examination, we found a voluminous purplish black ecchymosis of the anterior neck area. On internal examination, we found a voluminous epiglottis hematoma completely obstructing the upper airway. It was associated with other sites of intra-abdominal hemorrhage. Toxicological studies revealed the presence of warfarin at a concentration of 8.4 mg/L in peripheral blood, which supposes an INR well above 4.5. To conclude, we supposed death was due to asphyxia secondary to a spontaneous epiglottic hematoma caused by a high blood concentration of warfarin...
June 1, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28479314/epiglottitis-as-the-presenting-sign-of-mucous-membranous-pemphigoid-a-case-report
#13
Narin Nard Carmel-Neiderman, Ilana Kaplan, Yael Oestreicher-Kedem
Mucous membranous pemphigoid (MMP) is an autoimmune disease of the mucous membranes characterized by formation of subepithelial blisters. MMP commonly involves the ocular and oral mucosa. Laryngeal MMP is very rare, estimated as occurring in 1 of 10 million persons in the general population. It mostly affects the supraglottis, but may also involve other laryngeal sites as well as extralaryngeal areas. This report describes the clinical picture, workup to diagnosis, and differential diagnosis of an isolated epiglottic process in an elderly female who presented with isolated, long-standing, nonresolving epiglottitis, later diagnosed as MMP with epiglottal and oral involvement...
May 4, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28460811/do-we-need-a-change-in-ed-diagnostic-strategy-for-adult-acute-epiglottitis
#14
Sun Hwa Lee, Seong Jong Yun, Dong Hyeon Kim, Hyeon Hwan Jo, Seokyong Ryu
OBJECTIVES: To retrospectively evaluate the diagnostic performance of qualitative and quantitative radiographic parameters for diagnosing adult acute epiglottitis, and identify the prevalence and risk factors of false-negative neck radiography-based diagnosis of acute epiglottitis. METHODS: An emergency physician and a radiologist independently reviewed neck radiographs of 91 patients with laryngoscopy-confirmed acute epiglottitis and 91 control subjects between March 2010 and June 2016 for qualitative and quantitative radiographic parameters of acute epiglottitis, and concluded a diagnosis...
April 20, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28436129/use-of-an-electronic-brachytherapy-surface-applicator-to-treat-an-epiglottal-fibrosarcoma-in-a-dog
#15
Charles A Maitz, Katherine L Robinson
Presented is the case of an epiglottal fibrosarcoma in a dog. The location of the mass resulted in challenges in the delivery of adequate dose to the tumor, and herein we describe the treatment using an electronic brachytherapy source. The treatment consisted of four Gy fractions, twice daily for a total of 10 fractions (40 Gy total). Visual reevaluation two weeks after treatment supported adequate spatial dose delivery, and the patient was reportedly improved six weeks after treatment. We demonstrate that plesiotherapy using an electronic brachytherapy device is feasible and may be useful in the treatment of carefully selected veterinary tumors...
April 23, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28405749/the-anterior-commissure-of-the-human-larynx-revisited
#16
Jean Michel Prades, M Peoc'h, C Petcu, A Karkas, J M Dumollard, M Gavid
BACKGROUND: The anterior commissure (AC) of the human larynx is usually understood as an area of the glottis anteriorly situated between the two vocal folds inserting to the thyroid cartilage (TC). The pattern of spread of AC carcinoma could hypothesize that AC could include other structures of the ventral larynx as developmental anatomy could demonstrate. METHODS: Ten adult larynx specimens from donation program cadavers and 15 selected fetal specimens (from 11 to 34 weeks of amenorrhoea) were studied using microdissection and histological serial sections stained with hematoxylin-eosin and reticuline...
April 12, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28329099/effect-of-sleeping-position-on-upper-airway-patency-in-obstructive-sleep-apnea-is-determined-by-the-pharyngeal-structure-causing-collapse
#17
Melania Marques, Pedro R Genta, Scott A Sands, Ali Azarbazin, Camila de Melo, Luigi Taranto-Montemurro, David P White, Andrew Wellman
Objectives: In some patients, obstructive sleep apnea (OSA) can be resolved with improvement in pharyngeal patency by sleeping lateral rather than supine, possibly as gravitational effects on the tongue are relieved. Here we tested the hypothesis that the improvement in pharyngeal patency depends on the anatomical structure causing collapse, with patients with tongue-related obstruction and epiglottic collapse exhibiting preferential improvements. Methods: Twenty-four OSA patients underwent upper airway endoscopy during natural sleep to determine the pharyngeal structure associated with obstruction, with simultaneous recordings of airflow and pharyngeal pressure...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28291399/resection-and-primary-closure-of-edematous-glossoepiglottic-mucosa-in-a-dog-causing-laryngeal-obstruction
#18
Kevin J Schabbing, Jeffrey A Seaman
An approximately 22 mo old male neutered English bulldog was evaluated for acute onset of dyspnea with suspected brachycephalic obstructive airway syndrome (BOAS). Laryngoscopic exam revealed diffuse, severe edema and static displacement of redundant glossoepiglottic (GE) mucosa causing complete obstruction of the larynx and epiglottic entrapment. Static displacement of the GE mucosa was observed and determined to be the overriding component of dyspnea in this patient with BOAS. Resection and primary closure with two separate, simple continuous sutures of the GE mucosa were performed...
May 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28274235/multicenter-study-on-the-effectiveness-of-the-pre-epiglottic-baton-plate-for-airway-obstruction-and-feeding-problems-in-robin-sequence
#19
Christian F Poets, Christoph Maas, Wolfgang Buchenau, Joerg Arand, Anne Vierzig, Bert Braumann, Silvia Müller-Hagedorn
BACKGROUND: Treatment of Robin sequence is often either invasive or of unproven effectiveness. The pre-epiglottic baton plate (PEBP) is a well-studied alternative, yet is not widely applied internationally. We report on a prospective 3-center cohort study investigating this treatment. Based on an agreed protocol, parents of infants with Robin sequence referred to participating centers were offered enrollment, which involved taking a maxillary cast followed by endoscopy to fit the plate and sleep studies to monitor its effectiveness...
March 9, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28270658/a-very-rare-case-of-an-epiglottic-vallecular-cyst-presenting-with-active-bleeding-treated-via-endoscopic-band-ligation
#20
Hyun Chul Koh, Sun Gyo Lim, Kee Myung Lee
No abstract text is available yet for this article.
March 2017: American Journal of Gastroenterology
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