Arjen van der Veen, Mark Ramaekers, Marije Marsman, Hylke J F Brenkman, Maarten F J Seesing, Misha D P Luyer, Grard A P Nieuwenhuijzen, Jan H M B Stoot, Juul J W Tegels, Bas P L Wijnhoven, Wobbe O de Steur, Ewout A Kouwenhoven, Eelco B Wassenaar, Werner A Draaisma, Suzanne S Gisbertz, Donald L van der Peet, Anne M May, Jelle P Ruurda, Richard van Hillegersberg
BACKGROUND: Laparoscopic gastrectomy could reduce pain and opioid consumption, compared to open gastrectomy. However, it is difficult to judge the clinical relevance of this reduction, since these outcomes are reported in few randomized trials and in limited detail. METHODS: This secondary analysis of a multicenter randomized trial compared laparoscopic versus open gastrectomy for resectable gastric adenocarcinoma (cT1-4aN0-3bM0). Postoperative pain was analyzed by opioid consumption in oral morphine equivalents (OME, mg/day) at postoperative day (POD) 1-5, WHO analgesic steps, and Numeric Rating Scales (NRS, 0-10) at POD 1-10 and discharge...
October 2023: Journal of Gastrointestinal Surgery