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https://www.readbyqxmd.com/read/28918351/susceptibility-profiles-of-bacteria-causing-urinary-tract-infection-in-southern-tunisia
#1
Sonda Guermazi-Toumi, Sirine Boujlel, Mouna Assoudi, Riadh Issaoui, Sonia Tlili, Mohamed Ennaceur Hlaiem
OBJECTIVES: The aim of this study was to determine the epidemiological profile and the antibiotic resistance of bacteria responsible for urinary infections diagnosed in the department of microbiology of the regional hospital Houcine Bouzaiene (Gafsa) in the south west of Tunisia. METHODS: All the cytobacteriological urine samples analyzed from 1 January 2015 to 30 June 2016 were included in the study. The adopted criteria to define urinary infection were: leukocyturia >10(4)/ml and bacteriuria >10(5)CFU/ml...
September 13, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28910943/-study-on-antibiotic-resistance-of-escherichia-coli-and-enterococcus-colonized-in-intestine-of-neonates-from-neonatal-intensive-care-unit
#2
X F Li, Z J Liu, X Chen, J Li, Z G Cui, B Kan, J R Ma, J H Cui
Objective: To understand the antibiotic resistance of bacteria colonized in intestine of the neonates from neonatal intensive care unit (NICU) and provide evidence to guide clinical antibiotic treatment. Methods: From May, 2014 to May, 2015, a total of 572 stool samples were collected from the neonates of NICU in our hospital. Escherichia coli and Enterococcus were detected with VITEK-2 system. Results: A total of 328 strains of E. coli and 243 strains of Enterococcus were isolated respectively in this study...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28906365/the-antibiotic-susceptibility-patterns-of-uropathogens-among-children-with-urinary-tract-infection-in-shiraz
#3
Gholamreza Pouladfar, Mitra Basiratnia, Mojtaba Anvarinejad, Pejman Abbasi, Fatemeh Amirmoezi, Samaneh Zare
Urinary tract infection (UTI) is one of the most common bacterial infections in pediatrics. Delay in diagnosis and treatment can cause significant morbidity. The physicians knowledge regarding the symptoms, microorganisms that caused UTI, and effective antibiotics in a geographical area can help them to select the appropriate antibiotics. This study was performed to determine the prevalence of bacteria that cause UTI and their susceptibility to common antibiotics as well as the common symptoms and associated factors in children of Shiraz, Southern Iran...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28904483/fecal-carriage-of-extended-spectrum-beta-lactamase-producing-enterobacteriaceae-in-intensive-care-unit-patients
#4
Shalini Shenoy Mulki, Kavya Ramamurthy, Sevitha Bhat
BACKGROUND AND AIMS: Increasing and indiscriminate use of antibiotics has led the bacteria to develop resistance to most of the antibiotics. Beta-lactamase production is the mechanism of resistance to beta-lactams. Extended-spectrum beta-lactamases (ESBLs) have been found in the members of Enterobacteriaceae such as Escherichia coli and Klebsiella spp. which are the common health-care-associated pathogens. The aim was to study the rate of fecal carriage of ESBL-producing Enterobacteriaceae in patients admitted to the Intensive Care Unit (ICU) of tertiary care hospital and follow them subsequently for the development of infections...
August 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28893195/antimicrobial-resistance-in-bacterial-pathogens-among-hospitalized-children-with-community-acquired-lower-respiratory-tract-infections-in-dongguan-china-2011-2016
#5
Xiaoguang He, Mingyu Xie, Siping Li, Junqin Ye, Qi Peng, Qiang Ma, Xiaomei Lu, Baimao Zhong
BACKGROUND: Bacterial pathogens are a major cause of childhood community acquired lower respiratory tract infections (CA-LRTIs), and few data described the impact of antimicrobial resistance on children with CA-LRTIs. This study aims to investigate the antimicrobial resistance in common bacterial agents among hospitalized children with CA-LRTIs between 2011 and 2016 in Dongguan, China. METHODS: Sputum samples were collected from hospitalized children (0-5 years old) with CA-LRTIs in Dongguan Children's Hospital...
September 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28893132/prediction-of-infection-caused-by-extended-spectrum-beta-lactamase-producing-enterobacteriaceae-development-of-a-clinical-decision-making-nomogram
#6
Ana García-Tello, Helena Gimbernat, Cristina Redondo, Elisa Meilán, David M Arana, Juana Cacho, Juan F Dorado, Javier C Angulo
OBJECTIVE: This study aimed to assess the population at risk of infection by extended-spectrum beta-lactamase (ESBL)-producing organisms, using clinical criteria. MATERIALS AND METHODS: All urine cultures positive for Enterobacteriaceae in a Spanish hospital department from January 2010 to 2014 were reviewed. All isolates with ESBL-positive strains were collected, and isolates received during the first week of each month with ESBL-negative strains from symptomatic patients hospitalized or admitted to the emergency room...
September 11, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28888637/high-abundance-and-diversity-of-extended-spectrum-beta-lactamase-esbl-producing-escherichia-coli-in-faeces-and-tonsils-of-pigs-at-slaughter
#7
I Van Damme, C Garcia-Graells, W Biasino, T Gowda, N Botteldoorn, L De Zutter
This cross-sectional study investigates the abundance of cefotaxime-resistant Escherichia coli (CREC) in the faeces and tonsils of 96 pigs during slaughter. Moreover, different isolates from a selected number of pigs were tested to study the diversity of blaESBL genes within E. coli isolates from one pig. Cefotaxime-resistant bacteria (based on enumeration results on MacConkey agar supplemented with 1mg/L cefotaxime) were found in the faeces of 77 pigs (80%; 95% CI: 70-87%) and the tonsils of 91 pigs (95%; 95% CI: 88%-98%)...
September 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28887772/fortuitous-detection-of-cmy-2-and-dha-1-from-esbl-producing-escherichia-coli-in-senegal
#8
S Lo, F Robin, A Ba-Diallo, O F Diallo, M L Dia, R Beyrouthy, A Gaye-Diallo, A I Sow, R Bonnet
Cephalosporinases, which are naturally present in some enterobacterial species, can be mobilized by transposons, migrate to plasmids, and spread into other species such as Escherichia coli. The aim of this study was to characterize genes responsible for the production of extended-spectrum β-lactamases (ESBL) in E. coli isolates from urinary origin isolated in two hospitals in Senegal. Thus, a fortuitous discovery of plasmidic cephalosporinase in two isolates was noted. One of the isolates produced dha-1 associated with ESBL CTX-M-14, the other produced cmy-2, ESBL CTXM-15, tem-1 penicillinase, and oxa-1...
September 8, 2017: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28887202/hospital-sewage-water-a-reservoir-for-variants-of-new-delhi-metallo-%C3%AE-lactamase-blandm-and-esbl-producing-enterobacteriaceae
#9
Shadab Parvez, Asad U Khan
New Delhi metallo-β-lactamase (NDM)-producing Enterobacteriaceae has become a threat to public health. Hospital sewage is generally unexplored, having a potential for harbouring bacteria causing healthcare-associated infections. Hence, we initiated this study to monitor NDM-producing Enterobacteriaceae in hospital sewage water. We detected 32 isolates with blaNDM variants, 17 Escherichia coli, 8 Citrobacter freundii, 4 Shigella boydii, 2 Citrobacter braakii, and 1 Citrobacter farmeri in hospital sewage water, showing resistance to all antibiotics except colistin...
September 5, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28886559/sewage-treatment-effluents-in-delhi-a-key-contributor-of-%C3%AE-lactam-resistant-bacteria-and-genes-to-the-environment
#10
Manisha Lamba, Shaikh Ziauddin Ahammad
Rapid emergence of antibiotic resistance (AR) in developing countries is posing a greater health risk and increasing the global disease burden. Lack of access to safe drinking water, poor sanitation and inadequate sewage treatment facilities in these countries are fueling the problem associated with emergence of AR. Rapid proliferation of AR mediated by treated and untreated discharges from sewage treatment plants (STPs) is a prime public health concern. This study aims to understand the occurrence, fate, and routes of proliferation of carbapenem (KPC) and extended spectrum β-lactam (ESBL) resistant bacteria, and selected resistant genes in the samples collected from different unit operations in 12 STPs in New Delhi over two seasons...
August 28, 2017: Chemosphere
https://www.readbyqxmd.com/read/28883810/from-farms-to-markets-gram-negative-bacteria-resistant-to-third-generation-cephalosporins-in-fruits-and-vegetables-in-a-region-of-north-africa
#11
Ferielle Mesbah Zekar, Sophie A Granier, Muriel Marault, Lydia Yaici, Benoit Gassilloud, Charles Manceau, Abdelaziz Touati, Yves Millemann
The role of food in human exposure to antimicrobial-resistant bacteria is a growing food safety issue. The contribution of fruits and vegetables eaten raw to this exposure is still unclear. The evaluation of contamination levels of fruits, vegetables and the agricultural environment by third-generation cephalosporin (3GC)-resistant Gram-negative bacteria was performed by analyzing 491 samples of fruits and vegetables collected from 5 markets and 7 farms in Bejaia area, north-eastern Mediterranean coast of Algeria...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28882177/ampc-and-extended-spectrum-beta-lactamases-production-among-urinary-isolates-from-a-tertiary-care-hospital-in-lalitpur-nepal
#12
Suman Rai, Narayan Dutt Pant, Raju Bhandari, Anil Giri, Roshan Parajuli, Manoj Aryal, Jyoti Amatya, Vijay Kumar Sharma
BACKGROUND: Production of AmpC and extended spectrum beta-lactamases among urinary isolates has created a serious problem to the successful management of the urinary tract infection. The main purpose of this study was to determine the rates of the extended spectrum beta-lactamase (ESBL) production and AmpC beta-lactamase (ABL) production among urinary isolates. RESULTS: Among total 564 urinary isolates, 514 (91.1%) were gram negative bacilli and 50 (8.9%) were gram positive cocci...
September 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28877761/phenotypic-prevalence-of-extended-spectrum-beta-lactamases-among-enterobacteriaceae-isolated-at-mulago-national-referral-hospital-uganda
#13
Lucas Ampaire, Emmanuel Nduhura, Izale Wewedru
OBJECTIVE: Enterobacteriaceae, common causes of health care associated and community acquired infections are mainly treated with beta-lactam agents. Our study objective was to determine the prevalence and common enterobacteriaceae pathogen producing extended spectrum beta lactamases (ESBLs). The isolates were recovered from various clinical specimens. This was cross sectional study conducted between July 2016 and September 2016 at Mulago National Referral Hospital, Uganda. We used ChromID™ ESBL agar (Biomerieux SA, Lyon, France) and Vitek2 compact system GN83 card (BioMerieux Inc, Hazelwood, Missouri, USA) to detect and confirm presence of phenotypic extended spectrum beta lactamases producing pathogens respectively...
September 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28869169/-temocillin-and-urinary-tract-infections
#14
M Vallée, F Bruyère, F Roblot, L Brureau
INTRODUCTION: Temocillin is an alternative to treat urinary tract infections with bacteria producing extended spectrum beta-lactamase (ESBL). The objective is to evaluate the use of temocillin in urinary tract infections. MATERIALS AND METHODS: A systematic review of literature was carried out according to PRISMA criteria. All national and international recommendations have been reviewed regarding the indication of the use of temocillin in urology. Data collection on the use of temocillin in urinary tract infection has been performed from the Cochrane, LILACS and the Medline database...
August 28, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28867789/multiple-antibiotic-resistant-extended-spectrum-%C3%AE-lactamase-esbl-producing-enterobacteria-in-fresh-seafood
#15
Asem Sanjit Singh, Manjusha Lekshmi, Sreepriya Prakasan, Binaya Bhusan Nayak, Sanath Kumar
Members of the family Enterobacteriaceae include several human pathogens that can be acquired through contaminated food and water. In this study, the incidence of extended spectrum β-lactamase (ESBL)-producing enterobacteria was investigated in fresh seafood sold in retail markets. The ESBL-positive phenotype was detected in 169 (78.60%) isolates, with Escherichia coli being the predominant species (53), followed by Klebsiella oxytoca (27), and K. pneumoniae (23). More than 90% of the isolates were resistant to third generation cephalosporins, cefotaxime, ceftazidime, and cefpodoxime...
August 30, 2017: Microorganisms
https://www.readbyqxmd.com/read/28854680/the-ctx-m-14-plasmid-phk01-encodes-novel-small-rnas-and-influences-host-growth-and-motility
#16
Xinlei Jiang, Xuan Liu, Carmen O K Law, Ya Wang, Wai U Lo, Xing Weng, Ting Fung Chan, P L Ho, Terrence C K Lau
The dissemination of extended-spectrum β-lactamases (ESBLs) genes among bacteria is commonly achieved by plasmid conjugation. In the last decade, the CTX-M type enzyme was the most widespread and prevalent ESBLs in the world. In Hong Kong and mainland China, among the commonly found CTX-M-carrying plasmids were pHK01 and pHK01-like plasmids, which belong to incompatibility group FII (IncFII). In this work, we studied the physiological effect caused by the pHK01 plasmid in bacterial host Escherichia coli J53...
July 1, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/28836547/trends-in-antimicrobial-resistance-against-enterobacteriaceae-strains-isolated-from-blood-a-10-year-epidemiological-study-in-mainland-china-2004-2014
#17
Xiang-Jun Liu, Yuan Lyu, Yun Li, Feng Xue, Jian Liu
BACKGROUND: Antimicrobial resistance is a serious problem that compromises the empirical treatment of infections, resulting in a lack of effective antibiotics and high medical expenses. Here, we aimed to monitor the trends in antimicrobial resistance among Enterobacteriaceae isolated from blood samples in mainland China. METHODS: A total of 2240 Enterobacteriaceae isolates from blood were collected from hospitalized patients at 19 tertiary hospitals between October 2004 and June 2014...
September 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28834594/specific-detection-of-extended-spectrum-%C3%A3-lactamases-activities-with-a-ratiometric-fluorescent-probe
#18
Wuyu Mao, Xiana Qian, Jian Zhang, Lingying Xia, Hexin Xie
The dissemination of antimicrobial resistance around the world has be one of the biggest threats to global public health. The acquisition and expression of extended-spectrum -lactamases (ESBLs) in pathogenic bacterial are mainly responsible for the bacterial resistance to the third-generation of cephalosporins. Reported herein is a ratiometric fluorescent probe (CTX-HN) for the detection ESBLs activities. This imaging reagent adopts the core structure of cefotaxime as enzymatic recognition moiety, exhibiting excellent selectivity to ESBLs over other ß-lactamases...
August 23, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28834351/preliminary-insights-into-the-occurrence-of-similar-clones-of-extended-spectrum-beta-lactamase-producing-bacteria-in-humans-animals-and-the-environment-in-tanzania-a-systematic-review-and-meta-analysis-between-2005-and-2016
#19
REVIEW
J Seni, N Moremi, M Matee, F van der Meer, R DeVinney, S E Mshana, J D D Pitout
The emergence and spread of extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-PE) are complex and of the public health concern across the globe. This review aimed at assessing the ESBL-PE clones circulating in humans, animals and the environment to provide evidence-based insights for combating ESBL-PE using One Health approach. Systematic search from Medline/PubMed, Google Scholar and African Journals Online was carried out and retrieved nine eligible articles (of 131) based on phenotypic and genotypic detection of ESBL-PE between 2005 and 2016 in Tanzania...
August 22, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28815897/multidrug-resistant-enterobacteriaceae-pseudomonas-aeruginosa-and-vancomycin-resistant-enterococci-three-major-threats-to-hematopoietic-stem-cell-transplant-recipients
#20
REVIEW
Michael J Satlin, Thomas J Walsh
Hematopoietic stem cell transplant (HSCT) recipients are uniquely threatened by the emergence of multidrug-resistant (MDR) bacteria because these patients rely on immediate active antimicrobial therapy to combat bacterial infections. This review describes the epidemiology and treatment considerations for three challenging MDR bacterial pathogens in HSCT recipients: MDR Enterobacteriaceae, including extended-spectrum β-lactamase (ESBL)-producing and carbapenem-resistant Enterobacteriaceae (CRE), Pseudomonas aeruginosa, and vancomycin-resistant Enterococcus (VRE)...
August 16, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
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