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https://www.readbyqxmd.com/read/28536922/head-shaking-tilt-suppression-a-clinical-test-to-discern-central-from-peripheral-causes-of-vertigo
#1
F C Zuma E Maia, Renato Cal, Ricardo D'Albora, Sergio Carmona, Michael C Schubert
Tilt suppression refers to both tilting the head away from an Earth vertical axis and a reduction of an induced horizontal nystagmus. This phenomenon of reducing an induced horizontal nystagmus involves a circuitry of neurons within the vestibular nuclei and the cerebellum (collectively referred to as velocity storage) and signals from the otolith end organs. Lesions involving this circuitry can disrupt tilt suppression of induced horizontal nystagmus. We investigated the clinical value of combining the horizontal head-shaking nystagmus test with tilt suppression in 28 patients with unilateral peripheral vestibular hypofunction and 11 patients with lesions affecting the central nervous system...
May 23, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28530263/utricular-hypofunction-in-patients-with-type-2-diabetes-mellitus
#2
K Jáuregui-Renaud, C Aranda-Moreno, A Herrera-Rangel
The aim of this study was to assess the function of the utricle and horizontal semicircular canals in patients with type 2 diabetes mellitus receiving primary health care, with/without a history of falls. 101 patients with type 2 diabetes mellitus, 34 to 84 years old (26 with and 75 without a history of falls) and 51 healthy volunteers (40-83 years old) accepted to participate. They denied having a history of dizziness, vertigo, unsteadiness, hearing loss or neurological disorders. None of them were seeking care due to sensory or balance decline...
May 22, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28498271/epidemiology-of-dizzy-patient-population-in-a-neurotology-clinic-and-predictors-of-peripheral-etiology
#3
Thomas Muelleman, Matthew Shew, Rahul Subbarayan, Axel Shum, Kevin Sykes, Hinrich Staecker, James Lin
OBJECTIVE: To compare the proportion of peripheral versus nonperipheral dizziness etiologies among all patients, inclusive of those presenting primarily or as referrals, to rank diagnoses in order of frequency, to determine whether or not age and sex predict diagnosis, and to determine which subgroups tended to undergo formal vestibular testing. STUDY DESIGN: Retrospective cohort. SETTING: Academic neurotology clinic. PATIENTS: Age greater than 18 neurotology clinic patients with the chief complaint of dizziness...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28485653/vestibular-rehabilitation-in-benign-paroxysmal-positional-vertigo-reality-or-fiction
#4
Federica Bressi, Paola Vella, Manuele Casale, Antonio Moffa, Lorenzo Sabatino, Michele Antonio Lopez, Francesco Carinci, Rocco Papalia, Fabrizio Salvinelli, Silvia Sterzi
The objective of this article is to systematically review the evidence on the effectiveness of vestibular rehabilitation (VR) in patients with benign paroxysmal positional vertigo (BPPV). Relevant published studies about VR in BPPV were searched in PubMed, Google Scholar and Ovid using various keywords. We included trials that were available in the English language and did not apply publication year or publication status restrictions. Studies based on the VR in other peripheral and/or central balance disorders are excluded...
May 1, 2017: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/28485291/por%C3%A3-wnanie-cz%C3%A4-sto%C3%A5-ci-wyst%C3%A4-powania-objaw%C3%A3-w-wsp%C3%A3-%C3%A5-istniej%C3%A4-cych-w-grupie-pacjent%C3%A3-w-z-zawrotami-g%C3%A5-owy
#5
Jakub Šichnárek, Jana Vyskotová, Kateřina Macháčková, Eva Mrázková
BACKGROUND: Dizziness is the second most frequent symptom that make patients seek specialized examination. The effective solution of dizzy conditions requires treatment in cooperation with different branches of medicine. OBJECTIVE: To analyze data from the database of patients with vertigo examined in the Hearing and Balance Disorder Centre in Ostrava, to find out whether, and in what factors, the sets of patients with diagnosed central and peripheral vestibular syndrom differ from each other...
February 28, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28485288/the-influence-of-the-body-mass-index-bmi-on-selected-parameters-of-the-coagulation-system-in-patients-with-disorders-of-the-balance-system-taking-oral-contraceptives
#6
Marzena Bielińska, Joanna Urbaniak, Krzysztof Kuśmierczyk, Jurek Olszewski, Piotr Pietkiewicz
INTRODUCTION: The objective of the paper is to evaluate the influence of the body mass index (BMI) on selected parameters of the coagulation system in patients with disorders of the balance system taking oral contraceptives. MATERIAL AND METHODS: 105 young women participated in the study who were divided into 2 groups. Group I: 52 women disorders of the balance system taking hormonal contraceptives for at least 2 months, between the age of 20-49; Group II: 53 women with no disorders of the balance system taking hormonal contraceptives for at least 2 months, between the age of 18-40...
July 10, 2016: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28484820/-vertigo-and-dizziness-in-the-emergency-room
#7
REVIEW
A Zwergal, K Möhwald, M Dieterich
Vertigo and dizziness are among the most common chief complaints in the emergency department. Etiologies can be categorized into three subgroups: neurootological (vestibular), medical (especially cardiovascular, metabolic), and psychiatric disorders. The diagnostic approach in the emergency department is based on a systematic analysis of case history (type, time course of symptoms, modulating factors, associated symptoms), clinical examination of the vestibular, ocular motor, and cerebellar systems (head impulse test, nystagmus, skew deviation, positioning maneuver, test of gait and stance), as well as a basal monitoring (vital signs, 12-lead ECG, blood tests)...
May 8, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28476643/in-vivo-assessment-of-neurological-channelopathies-application-of-peripheral-nerve-excitability-studies
#8
REVIEW
Susan E Tomlinson, James Howells, David Burke
With the rapid evolution of understanding of neurological channelopathies comes a need for sensitive tools to evaluate patients in clinical practice. Neurological channelopathies with a single-gene basis can manifest as seizures, headache, ataxia, vertigo, confusion, weakness and neuropathic pain and it is likely that other genetic factors contribute to the phenotype of many of these disorders. Ion channel dysfunction can result in abnormal cell membrane excitability but utilisation of advanced neurophysiology techniques has lagged behind developments in clinical, genetic and imaging evaluation of channelopathies...
May 2, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28473800/central-positional-nystagmus-a-systematic-literature-review
#9
REVIEW
Nora K Macdonald, Diego Kaski, Yougan Saman, Amal Al-Shaikh Sulaiman, Amal Anwer, Doris-Eva Bamiou
OBJECTIVE: To provide a systematic review of the clinical and radiological features of lesion-induced central positional nystagmus (CPN) and identify salient characteristics that differentiate central from peripheral positional nystagmus (PN). METHODS: Systematic literature search according to the preferred reporting items for systematic reviews and meta-analysis. RESULTS: A total of 82 patients from 28 studies met the participants intervention, comparison, outcomes, and study designs criteria for inclusion...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28467976/increase-in-the-admission-of-stroke-mimics-after-change-in-emergency-shifts
#10
Mariana Vargas, Mariana Costa, Teresa Pinho E Melo, José M Ferro, Ana Catarina Fonseca
BACKGROUND: In 2010, changes were made to the shift pattern of neurology residents for cover in the Emergency Department at a university hospital. This resulted in a decrease in the number of emergency hours worked by neurology specialists and allowed for a natural quasi-experiment. AIM: We aimed to evaluate if changes to the number of emergency hours worked by neurology residents and specialist neurologists, (intervention) altered the number or pattern of admitted stroke mimics (SMs)...
May 4, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28429801/the-dizzy-patient-don-t-forget-disorders-of-the-central-vestibular-system
#11
REVIEW
Thomas Brandt, Marianne Dieterich
Vertigo and dizziness are among the most common complaints in neurology clinics, and they account for about 13% of the patients entering emergency units. In this Review, we focus on central vestibular disorders, which are mostly attributable to acute unilateral lesions of the bilateral vestibular circuitry in the brain. In a tertiary interdisciplinary outpatient dizziness unit, central vestibular disorders, including vestibular migraine, comprise about 25% of the established diagnoses. The signs and symptoms of these disorders can mimic those of peripheral vestibular disorders with sustained rotational vertigo...
April 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28429295/idiopathic-benign-paroxysmal-positional-vertigo-in-the-elderly-a-long-term-follow-up-study
#12
Seong-Chul Yeo, Seong-Ki Ahn, Ho Joong Lee, Hyun-Jin Cho, Sang-Wook Kim, Seung Hoon Woo, Sea-Yuong Jeon, Yeon-Hee Joo, Dong Gu Hur, Jung Je Park
BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral-type vertigo in the elderly. While some studies have investigated BPPV among the elderly, no study has focused on the isolated idiopathic BPPV (iBPPV) in the elderly. AIMS: To investigate the clinical features and recurrence rate in elderly patients diagnosed with iBPPV. METHODS: The authors prospectively reviewed the medical records of 627 patients diagnosed with BPPV, and a total of 370 patients fulfilled the inclusion criteria...
April 20, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28416082/final-diagnosis-of-patients-with-clinically-suspected-vestibular-neuritis-showing-normal-caloric-response
#13
Sung Hwan Ahn, Jung Eun Shin, Chang-Hee Kim
Vestibular neuritis is one of the most common peripheral causes of acute vestibular syndrome, of which the diagnosis is generally based on a comprehensive interpretation of clinical and laboratory findings following reasonable exclusion of other disorders. This study aimed to investigate the final diagnosis of patients admitted to hospital under the clinical impression of vestibular neuritis who showed no unilateral caloric paresis. Forty-five patients who visited the emergency department with isolated acute spontaneous vertigo were included...
April 13, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28397037/assessment-of-balance-and-vestibular-functions-in-patients-with-idiopathic-sudden-sensorineural-hearing-loss
#14
Jia Liu, Ren-Hong Zhou, Bo Liu, Yang-Ming Leng, Jing-Jing Liu, Dong-Dong Liu, Su-Lin Zhang, Wei-Jia Kong
This study investigated the relationship among the severity of hearing impairment, vestibular function and balance function in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). A total of 35 ISSNHL patients (including 21 patients with vertigo) were enrolled. All of the patients underwent audiometry, sensory organization test (SOT), caloric test, cervical vestibular-evoked myogenic potential (cVEMP) test and ocular vestibular-evoked myogenic potential (oVEMP) test. Significant relationship was found between vertigo and hearing loss grade (P=0...
April 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28395491/-the-significance-of-directional-preponderance-in-the-evaluation-of-vestibular-function-in-patients-with-vertigo
#15
J Wang, Y J Zhou, J Yu, J Gu
Objective: To analyze the relationship between directional preponderance (DP), spontaneous nystagmus(SN) and vestibular disorders, and to investigate the significance of DP in directing peripheral vestibular function in patients with vertigo. Methods: This was a retrospective analysis of 394 cases diagnosed with peripheral vestibular disease accompanied by vertigo from March 2012 to June 2014 in the Outpatient Department of the Eye & ENT Hospital of Fudan University. Results of static and dynamic posture equilibrium tests, SN, unilateral weakness(UW), and DP in videonystagmography(VNG) were analyzed and compared...
March 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28392043/the-impact-of-diabetes-on-mobility-balance-and-recovery-after-repositioning-maneuvers-in-individuals-with-benign-paroxysmal-positional-vertigo
#16
Linda J D'Silva, Susan L Whitney, Marcio Santos, Hongying Dai, Patricia M Kluding
AIM: The prevalence of benign paroxysmal positional vertigo (BPPV) is higher in people with type 2 diabetes (DM). The impact of DM on mobility, balance, and management of BPPV is unknown. This prospective study compared symptom severity, mobility and balance before and after the canalith repositioning maneuver (CRM) in people with posterior canal BPPV canalithiasis, with and without DM. METHODS: Fifty participants, BPPV (n=34) and BPPV+DM (n=16) were examined for symptom severity (dizziness handicap inventory, DHI), mobility (functional gait assessment, FGA), and postural sway (using an accelerometer in five conditions) before and after the CRM...
June 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28385058/postural-sway-in-individuals-with-type-2-diabetes-and-concurrent-benign-paroxysmal-positional-vertigo
#17
Linda D'Silva, Patricia M Kluding, Susan L Whitney, Hongying Dai, Marcio Santos
BACKGROUND AND PURPOSE: Diabetes has been shown to affect the peripheral vestibular end organs and is associated with an increase in the frequency of benign paroxysmal positional vertigo (BPPV). People with diabetes have higher postural sway; however, the impact of symptomatic BPPV on postural sway in individuals with diabetes is unclear. The purpose of this cross-sectional study was to examine postural sway in people with type 2 diabetes who have symptomatic, untreated BPPV (BPPVDM)...
April 6, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28375910/dizziness-in-the-outpatient-care-setting
#18
Terry D Fife
PURPOSE OF REVIEW: This article summarizes an approach to evaluating dizziness for the general neurologist and reviews common and important causes of dizziness and vertigo. RECENT FINDINGS: Improved methods of diagnosing patients with vertigo and dizziness have been evolving, including additional diagnostic criteria and characterization of some common conditions that cause dizziness (eg, vestibular migraine, benign paroxysmal positional vertigo, chronic subjective dizziness)...
April 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28346294/diagnosis-and-treatment-of-vestibular-neuritis-neuronitis-or-peripheral-vestibulopathy-pvp-open-questions-and-possible-answers
#19
Stefan C A Hegemann, Angela Wenzel
: The acute vestibular syndrome is a clinically defined entity consisting of vertigo or dizziness that develops acutely over minutes to hours and is accompanied by nausea/vomiting, gait instability, head motion intolerance, and nystagmus, while persisting over a day or more. When it is caused by a peripheral vestibular lesion and is not associated with clinically manifest auditory deficits, it is mostly labeled vestibular neuritis/neuronitis/neuropathy or sometimes peripheral vestibulopathy. Here, we propose hypotheses and discuss current research advances on viral or vascular factors in the pathogenesis, the recurrence, the site of lesion, old and new treatment options, contraindicated measures, the differential diagnosis, and the prognosis of vestibular neuritis/neuronitis/neuropathy or vestibulopathy...
June 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28280368/evidence-from-a-meta-analysis-is-nivolumabneurotoxic-in-cancer-patients
#20
Xiangyi Kong, Yanguo Kong
The aim of this study was to summarize the findings of previous studies focusing on whether the risks of certain neurotoxicities are correlated to the programmed death 1 (PD-1) inhibitor nivolumab versus other chemotherapy or immunotherapy drugs. Six eligible studies, including 3,023 patients, were considered in the meta-analysis. The risk ratios (RRs) of fatigue, headache, dysgeusia, vertigo, paresthesia, anxiety or malaise and peripheral neuropathy were 0.908 (95% confidence interval [95% CI]: 0.724, 1.138; P=0...
2017: OncoTargets and Therapy
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