keyword
https://read.qxmd.com/read/38536466/-practical-instructions-for-recording-vestibular-evoked-myogenic-potentials
#1
JOURNAL ARTICLE
Laura Fröhlich, Lea Babette Löffler
Recording of vestibular evoked myogenic potentials (VEMPs) is a well-established method for functional diagnostics of the otolith organs. VEMPs are vestibular reflexes of the sacculus und utriculus to acoustic stimulation by air-conducted sound or bone-conducted vibration and are recorded by surface electrodes from the cervical (cVEMP) and ocular (oVEMP) muscles. The results of VEMP recordings are part of the neuro-otologic test battery and enable diagnosis of various vestibular disorders or differentiation between non-vestibular and peripheral vestibular vertigo...
March 27, 2024: HNO
https://read.qxmd.com/read/38531544/application-of-bedside-hints-abcd-2-score-and-truncal-ataxia-to-differentiate-cerebellar-brainstem-stroke-from-vestibular-neuritis-in-the-emergency-room
#2
JOURNAL ARTICLE
Xinmin Liu, Zhaoxia Li, Yi Ju, Xingquan Zhao
BACKGROUND AND PURPOSE: Acute vestibular syndrome (AVS) typically manifests as isolated dizziness or vertigo with no apparent neurological impairments. However, distinguishing life-threatening stroke from innocuous peripheral vestibular lesions in the emergency room (ER) remains challenging. This study aimed to explore the ability of the head impulse-nystagmus-test of skew (HINTS) combined with truncal ataxia or ABCD2 score to differentiate stroke from peripheral vestibular disease in patients with AVS in the ER...
March 25, 2024: Stroke and Vascular Neurology
https://read.qxmd.com/read/38517997/adult-onset-congenital-cholesteatoma-in-the-hypotympanum-initially-presenting-as-bell-s-palsy-a-case-report
#3
JOURNAL ARTICLE
Pei-Shao Liao, Wei-Che Lan, Ching-Yuan Wang, Chia-Der Lin, Yu Aoh
INTRODUCTION: Cholesteatoma is a rare disease characterized by the accumulation of keratinized squamous epithelial cells in the middle ear or mastoid cavity. Vertigo and facial palsy, which are rare complications, may indicate erosion into the semicircular canals or the fallopian canal. PATIENT CONCERNS: A 40-year-old woman presented to our clinic with progressive right-sided hearing loss over 5 years (primary concern). Approximately 10 years ago, the patient had developed acute right-sided facial weakness with no additional symptoms...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38516542/delayed-diagnoses-in-patients-with-dizziness-in-the-us-commonwealth-of-virginia-and-the-tidewater-region
#4
JOURNAL ARTICLE
Kendra N Walker, Kevin M Guy, Peter G Volsky
OBJECTIVE: In a region of approximately 1.7 million people (Tidewater, coastal Virginia), identify secondary diagnoses in persons with dizziness. METHODS: This cross-sectional study utilizing TriNetX included individuals in the region of interest diagnosed with dizziness between 2010 and 2020. Subsequent diagnoses of vestibular disease or medical conditions possibly associated with dizziness in the same subjects were catalogued. RESULTS: During the study period, 31,670 subjects were identified with diagnoses of dizziness as a symptom; 18,390 subjects were subsequently given a dizziness-related nonvestibular diagnosis, and 930 were given a subsequent vestibular disease diagnosis...
December 2023: Otol Neurotol Open
https://read.qxmd.com/read/38504566/histaminergic-system-and-vestibular-function-in-normal-and-pathological-conditions
#5
JOURNAL ARTICLE
Brahim Tighilet, Jessica Trico, Emna Marouane, Andreas Zwergal, Christian Chabbert
Most neurotransmitter systems are represented in the central and peripheral vestibular system and are thereby involved both in normal vestibular signal processing and the pathophysiology of vestibular disorders. However, there is a special relationship between the vestibular system and the histaminergic system. The purpose of this review is to document how the histaminergic system interferes with normal and pathological vestibular function. In particular, we will discuss neurobiological mechanisms such as neuroinflammation that involve histamine to modulate and allow restoration of balance function in the situation of a vestibular insult...
March 19, 2024: Current Neuropharmacology
https://read.qxmd.com/read/38489201/sense-of-direction-in-vestibular-disorders
#6
JOURNAL ARTICLE
Alexander I G Moore, John F Golding, Anastasia Alenova, Patricia Castro, Adolfo M Bronstein
BACKGROUND: Our sense of direction (SOD) ability relies on the sensory integration of both visual information and self-motion cues from the proprioceptive and vestibular systems. Here, we assess how dysfunction of the vestibular system impacts perceived SOD in varying vestibular disorders, and secondly, we explore the effects of dizziness, migraine and psychological symptoms on SOD ability in patient and control groups. METHODS: 87 patients with vestibular disorder and 69 control subjects were assessed with validated symptom and SOD questionnaires (Santa Barbara Sense of Direction scale and the Object Perspective test)...
March 10, 2024: Journal of Vestibular Research: Equilibrium & Orientation
https://read.qxmd.com/read/38487330/vestibular-function-in-cases-of-posterior-semicircular-canal-canalolithiasis-and-cupulolithiasis
#7
JOURNAL ARTICLE
Xu Wenyan, Yue Lifeng, Wu Jing, Jiang Hui
OBJECTIVE: To analyze and compare the vestibular function of posterior canal cupulolithiasis and canalolithiasis. METHODS: The results of posterior cupulolithiasis in 45 cases, posterior canalolithiasis in 122 cases and 19 healthy controls were analyzed retrospectively. RESULTS: The abnormal rates of vHIT in the canalolithiasis group and the cupulolithiasis group were 42.6 and 37.8%, respectively, both higher than those in the control group (both p  < 0...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38487329/efficacy-of-vestibular-rehabilitation-and-its-facilitating-and-hindering-factors-from-real-world-clinical-data
#8
JOURNAL ARTICLE
Min-Ku Kim, So-Yeon Yun, Seonkyung Lee, Ja-Ok Lee, Soo-Yun Sung, Ju-Young Lee, Hyo-Jung Kim, Hye Youn Park, Jeong-Yoon Choi, Jae-Jin Song, Byung Yoon Choi, Ja-Won Koo, Ji-Soo Kim
BACKGROUND AND PURPOSE: Customized vestibular rehabilitation improved dizziness and imbalance in several randomized controlled trials. In the present study, we determined the efficacy of customized vestibular rehabilitation using real-world observational data. METHODS: In this retrospective observational study, we recruited 64 patients (median age = 60, interquartile range = 48-66.3) who completed the customized vestibular rehabilitation from January to December 2022...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38487324/can-head-sway-patterns-differentiate-between-patients-with-meniere-s-disease-vs-peripheral-vestibular-hypofunction
#9
JOURNAL ARTICLE
Jennifer L Kelly, Maura Cosetti, Anat V Lubetzky
BACKGROUND: Meniere's disease (MD) is defined by episodic vertigo, unilateral sensorineural hearing loss and fluctuating aural symptoms. Due to the variable clinical presentation, objective tests of MD may have significant diagnostic utility. Head kinematics derived from a head-mounted display (HMD) have demonstrated to be sensitive to vestibular dysfunction. The purpose of this pilot study was to investigate whether head sway can differentiate between patients with MD, vestibular hypofunction (VH) and healthy controls...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38438080/variants-of-posterior-semicircular-canal-involvement-in-benign-paroxysmal-positional-vertigo
#10
REVIEW
Octavio Garaycochea, Nicolás Pérez-Fernández
Benign paroxysmal positional vertigo is the most common cause of peripheral vertigo. It is characterized by short and recurrent episodes of vertigo, trigged by specific head movements that displace otoconia within the semicircular canals. The movement of dislodge otoconia from the utricle cause abnormal positional endolymphatic currents. Primary treatment involves reposition maneuvers aimed at moving the displaced otoconia out the affected canal, therefore correct identification of the affected canal is essential for the diagnosis...
March 2, 2024: Acta otorrinolaringologica española
https://read.qxmd.com/read/38431642/increased-prevalence-of-peripheral-vestibular-disorder-among-patients-with-fabry-disease
#11
JOURNAL ARTICLE
Tzong-Hann Yang, Sudha Xirasagar, Yen-Fu Cheng, Chin-Shyan Chen, Herng-Ching Lin
BACKGROUND: Although peripheral vestibular disorder is a non-fatal complication of Fabry disease, fatalities have been reported in some case reports and case series. To date, no studies have examined the relative risk of peripheral vestibular disorder in patients with Fabry disease compared to the general population without the condition. Due to the high prevalence of Fabry disease in East Asia and the potential shared pathogenic pathways between Fabry disease and vasculopathy, we conducted a study using a nationwide population-based dataset to compare the prevalence of peripheral vestibular disorder between patients with Fabry disease and matched comparison patients...
March 2, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38414598/effect-of-health-education-based-on-information-motivation-behavioral-skills-model-on-patients-with-unilateral-vestibular-dysfunction
#12
JOURNAL ARTICLE
Qiong Shi, Ruo-Jun Wu, Jiang Liu
BACKGROUND: Vestibular dysfunction (VH) is a common concomitant symptom of late peripheral vestibular lesions, which can be trauma, poisoning, infection, heredity, and neurodegeneration, but about 50% of the causes are unknown. The study uses the information-motivation-behavioral skills (IMB) model for health education, effectively improve the quality of life, increase their self-confidence, reduce anxiety and depression, and effectively improve the psychological state of patients. AIM: To explore the effect of health education based on the IMB model on the degree of vertigo, disability, anxiety and depression in patients with unilateral vestibular hypofunction...
February 16, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38403938/blood-biomarkers-for-the-differentiation-between-central-and-peripheral-vertigo-in-the-emergency-department-a-systematic-review-and-meta-analysis
#13
REVIEW
Vincent W Klokman, Fiona N Koningstein, Job W W Dors, Marieke S Sanders, Sam W Koning, Dominique P V de Kleijn, Kim E Jie
BACKGROUND/INTRODUCTION: In patients with acute vestibular syndrome (AVS), differentiating between stroke and nonstroke causes is challenging in the emergency department (ED). Correct diagnosis of vertigo etiology is essential for early optimum treatment and disposition. OBJECTIVES: The aim of this systematic review and meta-analysis was to summarize the published evidence on the potential of blood biomarkers in the diagnosis and differentiation of peripheral from central causes of AVS...
February 25, 2024: Academic Emergency Medicine
https://read.qxmd.com/read/38396174/cytokine-profiling-and-transcriptomics-in-mononuclear-cells-define-immune-variants-in-meniere-disease
#14
JOURNAL ARTICLE
Marisa Flook, Elena Rojano, Alvaro Gallego-Martinez, Alba Escalera-Balsera, Patricia Perez-Carpena, M Del Carmen Moleon, Rocio Gonzalez-Aguado, Victoria Rivero de Jesus, Emilio Domínguez-Durán, Lidia Frejo, Juan A G Ranea, Jose Antonio Lopez-Escamez
Meniere Disease (MD) is a chronic inner ear disorder characterized by vertigo attacks, sensorineural hearing loss, tinnitus, and aural fullness. Extensive evidence supporting the inflammatory etiology of MD has been found, therefore, by using transcriptome analysis, we aim to describe the inflammatory variants of MD. We performed Bulk RNAseq on 45 patients with definite MD and 15 healthy controls. MD patients were classified according to their basal levels of IL-1β into 2 groups: high and low. Differentially expression analysis was performed using the ExpHunter Suite, and cell type proportion was evaluated using the estimation algorithms xCell, ABIS, and CIBERSORTx...
February 23, 2024: Genes and Immunity
https://read.qxmd.com/read/38392978/clinical-efficacy-and-metabolomics-modifications-induced-by-polyphenol-compound-supplementation-in-the-treatment-of-residual-dizziness-following-semont-maneuver-in-benign-paroxysmal-positional-vertigo-bppv-of-the-posterior-semicircular-canal-psc-preliminary
#15
JOURNAL ARTICLE
Augusto Pietro Casani, Roberto Albera, Cristina Piras, Andrea Albera, Antonio Noto, Nicola Ducci, Luigi Atzori, Sergio Lucisano, Michele Mussap, Vassilios Fanos
Benign paroxysmal positional vertigo (BPPV) represents the most frequent cause of peripheral vertigo. In most cases, it is successfully treated using the canalith repositioning procedure, but it is often followed by continuous lightheadedness in the absence of vertigo or nystagmus (residual dizziness, RD). Our aim is to describe the clinical effectiveness and the urine metabolomics profile of treating these patients with polyphenol compound supplementation. We enrolled 30 patients reporting RD after BPPV of the posterior semicircular canal (PSC) successfully treated using the Semont maneuver...
January 25, 2024: Metabolites
https://read.qxmd.com/read/38361644/analysis-of-etiology-and-clinical-features-of-spontaneous-downbeat-nystagmus-a-retrospective-study
#16
JOURNAL ARTICLE
Sai Zhang, Yilin Lang, Wenting Wang, Yuexia Wu, Shuangmei Yan, Ting Zhang, Dong Li, Shaona Liu, Yongci Hao, Xu Yang, Ping Gu
OBJECTIVE: To investigate the topical diagnosis, possible etiology and mechanism of spontaneous downbeat nystagmus (sDBN) patients with dizziness/vertigo. METHODS: The clinical features of dizziness/vertigo patients accompanied with DBN were retrospectively reviewed in the Vertigo Center of our hospital from January 2018 to March 2021. The clinical features of dizziness/vertigo patients accompanied with DBN were reviewed. Comprehensive VNG, bithermal caloric testing, video-head-impulse test (vHIT), vestibular-evoked myogenic potentials (VEMP), head magnetic resonance imaging (MRI), three-dimensional fluid-attenuated incersion recovery magnetic resonance imaging (3D-FLAIR MRI) in the inner ear, serum immunology and other examinations were to determine the lesion site, and analyze its possible etiology and mechanism...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38336700/peripheral-vertigo-and-subsequent-risk-of-depression-and-anxiety-disorders-a-prospective-cohort-study-using-the-uk-biobank
#17
JOURNAL ARTICLE
Xiaowan Chen, Dang Wei, Fang Fang, Huan Song, Li Yin, Magnus Kaijser, Tiril Pedersen Gurholt, Ole Andreas Andreassen, Unnur Valdimarsdóttir, Kejia Hu, Maoli Duan
BACKGROUND: Peripheral vertigo is often comorbid with psychiatric disorders. However, no longitudinal study has quantified the association between peripheral vertigo and risk of psychiatric disorders. Furthermore, it remains unknown how the white matter integrity of frontal-limbic network relates to the putative peripheral vertigo-psychiatric disorder link. METHODS: We conducted a cohort study including 452,053 participants of the UK Biobank with a follow-up from 2006 through 2021...
February 9, 2024: BMC Medicine
https://read.qxmd.com/read/38297869/-dynamic-visual-acuity-screening-test-results-analysis-of-25-patients-with-peripheral-vertigo
#18
JOURNAL ARTICLE
Dong Zhao, Zigang Jiang, Chunjiao Li
Objective: To observe the results of dynamic visual acuity screening tests in patients with peripheral vertigo and explore its clinical significance. Methods: The number of 48 healthy volunteers were enrolled as control group and 25 peripheral vertigo patients as experimental group. In the experimental group, there are 12 patients with vestibular neuritis, 1 patient with Hunt syndrome, 5 patients with sudden deafness with vertigo and 7 patients with bilateral vestibular dysfunction. Horizontal and vertical dynamic visual acuity screening tests were performed on them...
February 2024: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://read.qxmd.com/read/38268758/sudden-unilateral-audiovestibular-loss-due-to-acute-labyrinthine-haemorrhage-can-be-missed-on-early-mri-brain-sequences-case-report
#19
JOURNAL ARTICLE
Patrick Harrison, John Blazak, Joshua Richmond, Kristy Fraser-Kirk, Aliese Hoffmann, Grant Collins, Benjamin K-T Tsang
BACKGROUND: Labyrinthine haemorrhage is a rare vascular disorder often presenting with the triad of acute vertigo, sudden sensorineural hearing loss and tinnitus. There are minimal reports on imaging progression over the acute period. INDEX CASE: A woman in her mid-40s presented with acute vertigo, sudden left-sided hearing loss and tinnitus, consistent with acute unilateral audiovestibular loss. Left peripheral vestibular hypofunction was confirmed acutely on video head impulse testing, and pure tone audiometry showed a profound left sensorineural hearing loss...
2024: BMJ neurology open
https://read.qxmd.com/read/38247216/a-diagnostic-framework-to-identify-vestibular-involvement-in-multi-sensory-neurological-disease
#20
JOURNAL ARTICLE
Amanda J Male, Sarah L Holmes, Nehzat Koohi, Magdalena Dudziec, Michael G Hanna, Gita M Ramdharry, Chiara Pizzamiglio, Robert D S Pitceathly, Diego Kaski
BACKGROUND AND PURPOSE: Identifying vestibular causes of dizziness and unsteadiness in multi-sensory neurological disease can be challenging, with problems typically attributed to central or peripheral nerve involvement. Acknowledging vestibular dysfunction as part of the presentation provides an opportunity to access targeted vestibular rehabilitation, for which extensive evidence exists. A diagnostic framework was developed and validated to detect vestibular dysfunction, benign paroxysmal positional vertigo or vestibular migraine...
January 21, 2024: European Journal of Neurology
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