Nicole M Ali, Ramin S Herati, Sapna A Mehta, Jeanette Leonard, Jake Miles, Bonnie E Lonze, Charles DiMaggio, Vasishta S Tatapudi, Zoe A Stewart, Nasser Alnazari, Henry J Neumann, Jeffrey Thomas, Katarzyna Cartiera, Elaina Weldon, Jennifer Michael, Christopher Hickson, Harris Whiteson, Karen Khalil, Jeffrey M Stern, Joseph R Allen, Michael Tuen, Sophie L Gray-Gaillard, Sabrina M Solis, Marie I Samanovic, Mark J Mulligan, Robert A Montgomery
BACKGROUND: Understanding immunogenicity and alloimmune risk following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in kidney transplant recipients is imperative to understanding the correlates of protection and to inform clinical guidelines. METHODS: We studied 50 kidney transplant recipients following SARS-CoV-2 vaccination and quantified their anti-spike protein antibody, donor-derived cell-free DNA (dd-cfDNA), gene expression profiling (GEP), and alloantibody formation...
September 14, 2023: Transplant Infectious Disease: An Official Journal of the Transplantation Society