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https://www.readbyqxmd.com/read/28192825/dynamic-alignment-analysis-in-the-osteoarthritic-knee-using-computer-navigation
#1
Ricardo Larrainzar-Garijo, David Murillo-Vizuete, Raul Garcia-Bogalo, David Escobar-Anton, Lissette Horna-Castiñeiras, Juan Vicente Peralta-Molero
The lower limb alignment is influenced by the geometry of the joint surfaces and surrounding soft tissue tension. The mechanical behavior changes in a normal, osteoarthritic, and postoperative knee. The purpose of this study is to determine the dynamic coronal femoral tibial mechanical angle (FTMA) in osteoarthritic knees using computer navigation. The authors hypothesize that there are different varus-valgus patterns between flexion and extension in the osteoarthritic knee. We conducted a transversal observational study and included patients with osteoarthritis who underwent primary navigation TKA (Orthopilot version 4...
February 13, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28160028/one-stage-bilateral-implantation-of-a%C3%A2-calcar-guided-short-stem-in%C3%A2-total-hip-arthroplasty-minimally-invasive-modified-anterolateral-approach-in-supine-position
#2
K P Kutzner, S Donner, M Schneider, J Pfeil, P Rehbein
OBJECTIVE: One-stage bilateral, muscle-preserving, calcar-guided implantation technique through the modified minimally invasive anterolateral approach in supine position. INDICATIONS: Bilateral primary/secondary osteoarthritis of the hip; bilateral femoral head necrosis; ASA I-III. CONTRAINDICATIONS: ASA IV; severe osteoporosis, other factors jeopardizing stable anchorage of cementless, calcar-guided short-stem; infection. SURGICAL TECHNIQUE: Supine position...
February 3, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28144820/a-preclinical-numerical-assessment-of-a-polyetheretherketone-femoral-component-in-total-knee-arthroplasty-during-gait
#3
Lennert de Ruiter, Dennis Janssen, Adam Briscoe, Nico Verdonschot
BACKGROUND: Conventional total knee replacement designs show high success rates but in the long term, the stiff metal components may affect bone quality of the distal femur. In this study we introduce an all-polymer total knee replacement device containing a PEEK femoral component on an UHMWPE tibial implant and study its mechanical integrity, fixation, and stress shielding of the periprosthetic femur. METHODS: The implant was analysed in finite element simulations of level gait, adopted from the ISO 14243-1 standard...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28128285/differentially-expressed-genes-and-canonical-pathway-expression-in-human-atherosclerotic-plaques-tampere-vascular-study
#4
Miska Sulkava, Emma Raitoharju, Mari Levula, Ilkka Seppälä, Leo-Pekka Lyytikäinen, Ari Mennander, Otso Järvinen, Rainer Zeitlin, Juha-Pekka Salenius, Thomas Illig, Norman Klopp, Nina Mononen, Reijo Laaksonen, Mika Kähönen, Niku Oksala, Terho Lehtimäki
Cardiovascular diseases due to atherosclerosis are the leading cause of death globally. We aimed to investigate the potentially altered gene and pathway expression in advanced peripheral atherosclerotic plaques in comparison to healthy control arteries. Gene expression analysis was performed (Illumina HumanHT-12 version 3 Expression BeadChip) for 68 advanced atherosclerotic plaques (15 aortic, 29 carotid and 24 femoral plaques) and 28 controls (left internal thoracic artery (LITA)) from Tampere Vascular Study...
January 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28127618/the-effect-of-valgus-and-varus-femoral-osteotomies-on-measures-of-anteversion-in-the-dog
#5
Rachel W Adams, Brad Gilleland, Farrah Monibi, Samuel P Franklin
OBJECTIVE: To determine whether femoral osteotomies that change frontal plane alignment without affecting torsion influence anteversion and inclination. METHODS: Femurs without deformity were scanned to create three-dimensional reconstructions. The femoral head-neck axis was identified by placement of a virtual intramedullary pin. A proximal osteotomy was simulated to create three conditions while keeping torsion constant: Normal, Coxa Valga (neck-shaft angle increased by 12°), and Coxa Vara (neck-shaft angle decreased by 12°)...
January 27, 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/28070260/relationship-between-bone-density-and-biochemical-markers-of-bone-among-two-groups-taking-carbamazepine-and-sodium-valproate-for-epilepsy-in-comparison-with-healthy-individuals-in-yazd
#6
Abolghasem Rahimdel, Ali Dehghan, Mahboubeh Abolhassani Moghadam, Ali Mellat Ardekani
INTRODUCTION: Chronic antiepileptic therapy has been associated with metabolic bone diseases including osteomalacia and osteoporosis. The aim of this study was to determine frequency of changes in biochemical and bone mineral density (BMD) in adults receiving valproaic acid (VPA) & carbamazepine (CBZ). METHODS: In a cross sectional study evaluating adults (age 20-50 y) epileptic patients receiving valproic acid or carbamazepine for at least 2 years. This study was conducted from May 2014 to May 2015 in Shahid Sadoughi Hospital of Yazd University of Medical Science, Yazd, Iran...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28056981/arterial-stiffness-endothelial-and-cognitive-function-in-subjects-with-type-2-diabetes-in-accordance-with-absence-or-presence-of-diabetic-foot-syndrome
#7
Antonino Tuttolomondo, Alessandra Casuccio, Giovanni Guercio, Carlo Maida, Alessandro Del Cuore, Domenico Di Raimondo, Irene Simonetta, Danilo Di Bona, Rosaria Pecoraro, Vittoriano Della Corte, Eliana Gulotta, Gaspare Gulotta, Antonio Pinto
BACKGROUND: Endothelial dysfunction is an early marker of cardiovascular disease so endothelial and arterial stiffness indexes are good indicators of vascular health. We aimed to assess whether the presence of diabetic foot is associated with arterial stiffness and endothelial function impairment. METHODS: We studied 50 subjects with type 2 diabetes mellitus and diabetic foot syndrome (DFS) compared to 50 diabetic subjects without diabetic foot, and 53 patients without diabetes mellitus, by means of the mini mental state examination (MMSE) administered to evaluate cognitive performance...
January 6, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28048517/tu-h-brc-03-evaluation-of-very-high-energy-electron-vhee-beams-in-comparison-to-vmat-and-pbs-treatment-plans
#8
E Schueler, K Eriksson, E Hynning, B Loo, P Maxim
PURPOSE: The aim of this study was to evaluate the performance of very high-energy electron (VHEE) beams in comparison to clinically delivered treatment plans generated with volumetric modulated arc therapy (VMAT) and proton pencil beam scanning (PBS) technology. METHODS: Three clinical cases were selected (prostate, lung, and pediatric CNS). The VHEE plans were calculated in the Monte Carlo EGSnrc code and pencil beam doses were calculated using the DOSxyznrc MC code for 100 and 200 MeV beams...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27993496/no-difference-in-periprosthetic-bone-loss-and-fixation-between-a-standard-length-stem-and-a-shorter-version-in-cementless-total-hip-arthroplasty-a-randomized-controlled-trial
#9
Jörg Schilcher, Ingemar Ivarsson, Rico Perlbach, Lars Palm
BACKGROUND: Cementless femoral stems in total hip arthroplasty provide dependable clinical and radiographic results in the treatment of osteoarthritis. Stem length might affect the preservation of proximal bone stock and stability. We hypothesized that a shorter stem decreases proximal bone loss without affecting implant stability. METHODS: We randomly assigned 60 patients aged between 50 and 70 years to either a standard cementless femoral stem or a 35-mm shorter version...
November 17, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27992642/revision-total-hip-arthroplasty-using-the-cement-in-cement-technique
#10
Derek F Amanatullah, Graham D Pallante, Lorena V Floccari, George I Vasileiadis, Robert T Trousdale
The cement-in-cement technique is useful in the setting of revision total hip arthroplasty (THA), especially to gain acetabular exposure, change a damaged or loose femoral component, or change the version, offset, or length of a fixed femoral component. The goal of this retrospective study was to assess the clinical and radiographic characteristics of revision THA using the cement-in- cement technique. Between 1971 and 2013, a total of 63 revision THAs used an Omnifit (Osteonics, Mahwah, New Jersey) or Exeter (Howmedica, Mahwah, New Jersey) stem and the cement-in-cement technique at the senior author's institution...
December 19, 2016: Orthopedics
https://www.readbyqxmd.com/read/27957636/bony-morphology-of-the-hip-in-professional-ballet-dancers-compared-to-athletes
#11
Susan Mayes, April-Rose Ferris, Peter Smith, Andrew Garnham, Jill Cook
OBJECTIVES: To compare hip bony morphology between ballet dancers and a sporting control group and to determine the relationship with hip pain. METHODS: Thirty-three professional ballet dancers and 33 age- and sex-matched athletes completed questionnaires, including the Copenhagen Hip and Groin Outcome Score (HAGOS), and underwent clinical testing and 3.0-T magnetic resonance imaging to measure acetabular coverage with lateral centre edge angles, femoral head-neck junction concavity with alpha angles at anterior and superior positions, femoral neck-shaft angles, and acetabular version angles...
December 12, 2016: European Radiology
https://www.readbyqxmd.com/read/27927616/safety-of-hip-anchor-insertion-from-the-midanterior-and-distal-anterolateral-portals-with-a-straight-drill-guide-a-cadaveric-study
#12
Ryan M Degen, Lazaros Poultsides, Stephanie W Mayer, Angela E Li, Struan H Coleman, Anil S Ranawat, Danyal H Nawabi, Bryan T Kelly
BACKGROUND: During arthroscopic labral refixation, suture anchors are typically inserted from either the midanterior (MA) portal or the distal anterolateral (DALA) portal; however, no studies have previously compared these techniques. PURPOSE/HYPOTHESIS: The purpose of this study was to compare acetabular rim accessibility and associated complication rates of anchor insertion from these portals. We hypothesized that rim access would be better from the DALA portal...
December 7, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27900304/clinical-outcome-of-design-modifications-to-the-cls-spotorno-stem-in-total-hip-replacement
#13
Angelo Graceffa, Pier Francesco Indelli, Leonardo Latella, Paolo Poli, Alexander Fulco, Massimiliano Marcucci
PURPOSE: historically, the original CLS Spotorno Stem has demonstrated excellent survival. The design of this stem was recently modified, resulting in the introduction of a shorter, modular version (CLS Brevius). The purpose of the current study was to evaluate the functional, radiological and survivorship outcomes of the cementless CLS Brevius Stem in a multi-surgeon, single center, consecutive series study at two years post-surgery. METHODS: the Authors performed 170 total hip arthroplasties in 155 patients using the shorter, triple-taper stem design (CLS Brevius)...
July 2016: Joints
https://www.readbyqxmd.com/read/27891409/distal-femur-locking-plate-the-answer-to-all-distal-femoral-fractures
#14
Jagandeep Singh Virk, Sudhir Kumar Garg, Parmanand Gupta, Vivek Jangira, Jagdeep Singh, Sudhir Rana
INTRODUCTION: Good results have been published by researchers with distal femur nail, dynamic condylar screw and even addition of a medial plate to a distal femur locking plate for treating distal femur fractures. By this study, we explore the capability of a distal femur locking plate to counter distal femur fractures of extra- articular, partial or intra- articular nature. Positive results have been published by various groups from all over the world. AIM: To study the functional and radiological outcome of distal femoral fractures in skeletally mature patients treated by open reduction and internal fixation with distal femur locking plate...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27847852/assessment-of-diagnostic-value-of-single-view-dynamic-technique-in-diagnosis-of-developmental-dysplasia-of-hip-a-comparison-with-static-and-dynamic-ultrasond-techniques
#15
Seyed Ali Alamdaran, Sahar Kazemi, Ali Parsa, Mohammad Hallaj Moghadam, Ali Feyzi, Reza Mardani
BACKGROUND: Developmental dysplasia of hip (DDH) is a common childhood disorder, and ultrasonography examination is routinely used for screening purposes. In this study, we aimed to evaluate a modified combined static and dynamic ultrasound technique for the detection of DDH and to compare with the results of static and dynamic ultrasound techniques. METHODS: In this cross-sectional study, during 2013- 2015, 300 high-risk infants were evaluated by ultrasound for DDH...
October 2016: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/27830486/three-patterns-of-acetabular-deficiency-are-common-in-young-adult-patients-with-acetabular-dysplasia
#16
Jeffrey J Nepple, Joel Wells, James R Ross, Asheesh Bedi, Perry L Schoenecker, John C Clohisy
BACKGROUND: Detailed recognition of the three-dimensional (3-D) deformity in acetabular dysplasia is important to help guide correction at the time of reorientation during periacetabular osteotomy (PAO). Common plain radiographic parameters of acetabular dysplasia are limited in their ability to characterize acetabular deficiency precisely. The 3-D characterization of such deficiencies with low-dose CT may allow for more precise characterization. QUESTIONS/PURPOSES: The purposes of this study were (1) to determine the variability in 3-D acetabular deficiency in acetabular dysplasia; (2) to define subtypes of acetabular dysplasia based on 3-D morphology; (3) to determine the correlation of plain radiographic parameters with 3-D morphology; and (4) to determine the association of acetabular dysplasia subtype with patient clinical characteristics including sex, range of motion, and femoral version...
November 9, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27826791/rational-derivation-extension-and-cyclization-of-self-inhibitory-peptides-to-target-tgf-%C3%AE-bmp-signaling-in-onfh
#17
Zhenhong Zhu, Chi Zhang, Wenqi Song
The human transforming growth factor β (TGF-β)/bone morphogenic protein (BMP) signaling has been recognized as an attractive target to suppress fibroblast activation in osteonecrosis of the femoral head (ONFH). Here, we reported successful derivation of a self-inhibitory peptide from the crystal complex interface of TGF-β with its cognate receptor TβRI using rational molecular design and in vitro binding assay. Computational modeling suggested that the peptide possesses a large flexibility and would incur considerable entropy penalty...
February 2017: Amino Acids
https://www.readbyqxmd.com/read/27807716/the-contribution-of-intellectuals-to-the-history-of-traumatology-during-the-renaissance-treatment-of-femoral-fracture-through-fran%C3%A3-ois-rabelais-glossocomion
#18
REVIEW
Francesco Manzini, Claudio Manzini, Giancarlo Cesana, Michele Augusto Riva
During the Middle Ages and the Renaissance, intellectuals often included clinical cases and medical descriptions in their literary works. These authors appeared to be more interested in internal and infectious diseases rather than in musculoskeletal disorders and orthopaedics. François Rabelais (1490-1553) was one of the most renowned humanists and philologists of the sixteenth century. He was also a physician with an interest in translating ancient texts of medical authors. Rabelais rediscovered a device for treating femoral fracture originally described by the Roman physician Galen and named as glossocomion...
November 2, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27801641/a-systematic-review-and-economic-evaluation-of-bisphosphonates-for-the-prevention-of-fragility-fractures
#19
Sarah Davis, Marrissa Martyn-St James, Jean Sanderson, John Stevens, Edward Goka, Andrew Rawdin, Susi Sadler, Ruth Wong, Fiona Campbell, Matt Stevenson, Mark Strong, Peter Selby, Neil Gittoes
BACKGROUND: Fragility fractures are fractures that result from mechanical forces that would not ordinarily result in fracture. OBJECTIVES: To evaluate the clinical effectiveness and safety of bisphosphonates [alendronic acid (Fosamax(®) and Fosamax(®) Once Weekly, Merck Sharp & Dohme Ltd), risedronic acid (Actonel(®) and Actonel Once a Week(®), Warner Chilcott UK Ltd), ibandronic acid (Bonviva(®), Roche Products Ltd) and zoledronic acid (Aclasta(®), Novartis Pharmaceuticals UK Ltd)] for the prevention of fragility fracture and to assess their cost-effectiveness at varying levels of fracture risk...
October 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27793175/the-effectiveness-of-the-paclitaxel-coated-luminor%C3%A2-balloon-catheter-versus-an-uncoated-balloon-catheter-in-superficial-femoral-and-popliteal-arteries-in-preventing-vessel-restenosis-or-reocclusion-study-protocol-for-a-randomized-controlled-trial
#20
U Teichgräber, R Aschenbach, D Scheinert, T Zeller, K Brechtel, M Thieme, E Blessing, M Treitl, M Lichtenberg, P von Flowtow, B Vogel, M Werk, V Riambau, A Wienke, T Lehmann, S Sixt
BACKGROUND: The aim of this investigator-initiated trial is to evaluate the safety and efficacy of the novel Luminor® paclitaxel-coated drug-eluting balloon (DEB) catheter (iVascular, S.L.U., Barcelona, Spain) in inhibiting restenosis and in ensuring long-term vascular patency. METHODS/DESIGN: This is a multicenter randomized controlled trial to evaluate the Luminor® paclitaxel-coated DEB catheter for stenotic or occlusive lesions (length ≤15 cm) in the superficial femoral artery (SFA) and the popliteal artery (PA) up to the P1 segment compared to the noncoated, plain old balloon angioplasty (POBA) catheter...
October 28, 2016: Trials
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