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https://www.readbyqxmd.com/read/28197692/feasibility-of-establishing-an-australian-acl-registry-a-pilot-study-by-the-australian-orthopaedic-association-national-joint-replacement-registry-aoanjrr
#1
Christina Lekkas, Richard Clarnette, Stephen E Graves, Sophia Rainbird, David Parker, Michelle Lorimer, Roger Paterson, Justin Roe, Hayden Morris, Julian A Feller, Peter Annear, Ben Forster, David Hayes
PURPOSE: Rupture of the anterior cruciate ligament (ACL) is a common and debilitating injury that impacts significantly on knee function and risks the development of degenerative arthritis. The outcome of ACL surgery is not monitored in Australia. The optimal treatment is unknown. Consequently, the identification of best practice in treating ACL is crucial to the development of improved outcomes. The Australian Knee Society (AKS) asked the Australian Orthopaedic Association (AOA) to consider establishing a national ACL registry...
February 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28196043/measures-of-the-appropriateness-of-elective-orthopaedic-joint-and-spine-procedures
#2
Jeffrey N Katz, Amelia R Winter, Gillian Hawker
Total knee arthroplasty and total hip arthroplasty are 2 of the most commonly performed elective orthopaedic procedures. They are remarkably successful in relieving pain and improving function in individuals with advanced, symptomatic arthritis. Since, in addition to providing benefits, these procedures pose risks, it is important to provide clinicians with guidance in determining which patients should undergo total joint replacement surgery. The development of the RAND approach in 1986 and its application to total hip and knee replacement have enabled clinicians, payers, and others to assess the appropriateness of past and current procedures for particular patients...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28194384/correlation-between-ahlb%C3%A3-ck-radiographic-classification-and-anterior-cruciate-ligament-status-in-primary-knee-arthrosis
#3
Glaucus Cajaty Martins, Gilberto Luis Camanho, Leonardo Marcolino Ayres, Eduardo Soares de Oliveiras
OBJECTIVE: To correlate the Ahlbäck radiographic classification with the anterior cruciate ligament (ACL) status in knee arthritis patients. METHODS: The study evaluated 89 knees of patients who underwent total knee arthroplasty due to primary osteoarthritis: 16 male and 69 females, with mean age 69.79 years (53-87 years). Osteoarthritis was classified radiographically by the Ahlbäck radiographic classification into five grades. The ACL was classified in the surgery as present or absent...
January 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28192100/disease-modifying-anti-rheumatic-activity-of-the-alkaloid-montanine-on-experimental-arthritis-and-fibroblast-like-synoviocytes
#4
Mirian Farinon, Vanessa S Clarimundo, Graziele P R Pedrazza, Pércio S Gulko, José A S Zuanazzi, Ricardo M Xavier, Patricia G de Oliveira
Montanine is an alkaloid isolated from Rhodophiala bifida bulb with potential anti-arthritic activity. In this context, we evaluated wether montanine has a disease modifying anti-rheumatic activity in two arthritis models and its effect in vitro on lymphocyte proliferation and on invasiveness of fibroblast-like synoviocytes (FLS). Antigen-induced arthritis (AIA) was performed in Balb/C mice with methylated bovine serum albumin, and nociception and leukocytes migration into the knee joint were evaluated. Collagen-induced arthritis (CIA) was performed in DBA/1J mice, and arthritis development and severity were assessed by clinical and histological scoring and articular nociception...
February 10, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28185415/relationship-between-clinical-evaluation-and-ultrasound-assessment-of-rheumatoid-arthritis-patients-using-a-12-joint-score
#5
Marcos Cerqueira, Filipa Teixeira, Joana Sousa Neves, Daniela Peixoto, Maria Carmo Afonso, José A Costa
AIM: To identify if the use of a systematic ultrasound (US) evaluation has relevance in the determination of disease activity in rheumatoid arthritis patients on biological disease-modifying anti-rheumatic drug treatment. METHODS: A 12 joint US assessment was performed on the same day of the routine clinical examination. Both Grey-scale (GS) and Power Doppler (PD) were graded semi-quantitatively (0-3 scale). RESULTS: Forty-one patients were included...
February 9, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28184957/partial-meniscectomy-provides-no-benefit-for-symptomatic-degenerative-medial-meniscus-posterior-root-tears
#6
Aaron J Krych, Nick R Johnson, Rohith Mohan, Diane L Dahm, Bruce A Levy, Michael J Stuart
PURPOSE: Medial meniscus posterior root tears (MMPRTs) are recognized as a source of pain and dysfunction, but treatment options remain a challenge. The purpose of the study was to determine (1) the efficacy of partial meniscectomy to treat MMPRTs compared to a matched group of non-operatively treated MMPRTs, and (2) risk factors for worse clinical and radiographic outcome. METHODS: This retrospective comparative study was performed to include patients with complete, isolated MMPRTs with documented clinical symptoms and were treated with arthroscopic partial meniscectomy (PMM) and a minimum 2-year follow-up...
February 9, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28170179/comparative-clinical-observation-of-arthroscopic-microfracture-in-the-presence-and-absence-of-a-stromal-vascular-fraction-injection-for-osteoarthritis
#7
Phu Dinh Nguyen, Tung Dang-Xuan Tran, Huynh Ton-Ngoc Nguyen, Hieu Trung Vu, Phuong Thi-Bich Le, Nhan Lu-Chinh Phan, Ngoc Bich Vu, Ngoc Kim Phan, Phuc Van Pham
Osteoarthritis (OA) is a degenerative cartilage disease that is characterized by a local inflammatory reaction. Consequently, many studies have been performed to identify suitable prevention and treatment interventions. In recent years, both arthroscopic microfracture (AM) and stem cell therapy have been used clinically to treat OA. This study aimed to evaluate the clinical effects of AM in the presence and absence of a stromal vascular fraction (SVF) injection in the management of patients with OA. Thirty patients with grade 2 or 3 (Lawrence scale) OA of the knee participated in this study...
January 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28168545/prevalence-of-musculoskeletal-disorders-in-azar-cohort-population-in-northwest-of-iran
#8
Sousan Kolahi, Alireza Khabbazi, Aida Malek Mahdavi, Amid Ghasembaglou, Arezoo Ghasembaglou, Nayyereh Aminisani, Mohammad Hossein Somi, Fariba Heidari
Musculoskeletal disorders (MSDs) are considered as major public health problems. The purpose of this study was to determine the prevalence of MSDs in Azar cohort population in northwest of Iran. Azar cohort study is a state level of a national cohort project (PERSIAN) which began in 2014. All adults over 35 years old in Khamene city in East Azarbaijan province were recruited for the pilot phase of the Azar cohort. For the purpose of the current study, a total of 952 subjects age range of 35-70 who completed the Community Oriented Program for the Control of Rheumatic Disease (COPCORD) questionnaire as supplementary were included...
February 6, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28167879/early-revision-surgery-for-tibial-plateau-non-union-and-mal-union
#9
Dominic L Van Nielen, Christopher S Smith, David L Helfet, Peter Kloen
BACKGROUND: Although relatively rare, non-unions and mal-unions of tibial plateau fractures present significant challenges for the orthopedic surgeon. With careful pre-operative planning, tibial plateau mal-union or non-union revision surgery with intra-articular and varus opening osteotomies can provides good functional results when performed early (within 1 year) after primary surgical procedure. QUESTIONS/PURPOSES: We present our treatment algorithm for approaching and treating non-union or mal-union of tibial plateau fractures...
February 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28167299/1-25-oh-2d3-and-calcipotriol-its-hypocalcemic-analog-exert-a-long-lasting-anti-inflammatory-and-anti-proliferative-effect-in-synoviocytes-cultured-from-patients-with-rheumatoid-arthritis-and-osteoarthritis
#10
Johanna A Huhtakangas, Johanna Veijola, Sanna Turunen, Anna Karjalainen, Maarit Valkealahti, Tomi Nousiainen, Susanna Yli-Luukko, Olli Vuolteenaho, Petri Lehenkari
OBJECTIVES: We investigated the effects of 1,25-dihydroxy vitamin D3 (1,25(OH)2D3), i.e. biologically active vitamin D and calcipotriol, a vitamin D analogue, on growth and secretion of inflammatory mediators in synovial stromal cells (SSC) of patients with rheumatoid arthritis (RA) or osteoarthritis (OA). METHODS: Synovial stromal cells (SSC) isolated during knee prosthesis surgery from four patients with RA and four with OA were exposed to 1,25(OH)2D3 or calcipotriol with or without stimulation of cells with IL-1β or TNF-α...
February 3, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28166793/cytotoxic-t-cells-modulate-inflammation-and-endogenous-opioid-analgesia-in-chronic-arthritis
#11
Uta Baddack-Werncke, Melanie Busch-Dienstfertig, Sara González-Rodríguez, Santhosh Chandar Maddila, Jenny Grobe, Martin Lipp, Christoph Stein, Gerd Müller
BACKGROUND: This study examined the development of chronic pain, a cardinal symptom of rheumatoid arthritis (RA), in mice with antigen- and collagen-induced arthritis (ACIA). Since the role of CD8(+) T cells in arthritis is controversial, we investigated the consequences of CD8-depletion on arthritis development and opioid modulation of pain in this novel model of chronic autoimmune arthritis. METHODS: Disease severity in control and CD8-depleted animals was determined by histological assessment of knee-joint sections and measurement of autoantibody formation...
February 6, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28164052/treatment-of-stiff-elbow-in-young-patients-with-interpositional-arthroplasty-for-mobility-case-series
#12
R Sivakumar, V SomaSheker, Prahalad Kumar Shingi, T Vinoth, M Chidambaram
INTRODUCTION: The elbow is a complex joint involving many articulations and complex biomechanics come into play. Elbow motion is crucial to upper limb movement that loss of 50% of elbow function equals to loss of 80% of upper extremity global function. Restoring movement and stability is challenging to the surgeon while treating a stiff elbow. Unlike other arthroplasties of hip and knee, total elbow arthroplasty (TEA) may not be a primary treatment. Interpositional arthroplasty (IPA) can be considered a viable option in posttraumatic arthritis of elbow in young patients...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28162839/a-systematic-review-of-measurement-properties-of-patient-reported-outcome-measures-used-in-patients-undergoing-total-knee-arthroplasty
#13
Joel J Gagnier, Megan Mullins, Hsiaomin Huang, Danica Marinac-Dabic, Anna Ghambaryan, Benjamin Eloff, Faisal Mirza, Manuel Bayona
BACKGROUND: While clinical research on total knee arthroplasty (TKA) outcomes is prevalent in the literature, studies often have poor methodological and reporting quality. A high-quality patient-reported outcome instrument is reliable, valid, and responsive. Many studies evaluate these properties, but none have done so with a systematic and accepted method. The objectives of this study were to identify patient-reported outcome measures (PROMs) for TKA, and to critically appraise, compare, and summarize their psychometric properties using accepted methods...
January 10, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28162781/intra-articular-corticosteroids-versus-intra-articular-corticosteroids-plus-methotrexate-in-oligoarticular-juvenile-idiopathic-arthritis-a-multicentre-prospective-randomised-open-label-trial
#14
Angelo Ravelli, Sergio Davì, Giulia Bracciolini, Angela Pistorio, Alessandro Consolaro, Evert Hendrik Pieter van Dijkhuizen, Bianca Lattanzi, Giovanni Filocamo, Sara Verazza, Valeria Gerloni, Maurizio Gattinara, Irene Pontikaki, Antonella Insalaco, Fabrizio De Benedetti, Adele Civino, Giuseppe Presta, Luciana Breda, Valentina Marzetti, Serena Pastore, Silvia Magni-Manzoni, Maria Cristina Maggio, Franco Garofalo, Donato Rigante, Marco Gattorno, Clara Malattia, Paolo Picco, Stefania Viola, Stefano Lanni, Nicolino Ruperto, Alberto Martini
BACKGROUND: Little evidence-based information is available to guide the treatment of oligoarticular juvenile idiopathic arthritis. We aimed to investigate whether oral methotrexate increases the efficacy of intra-articular corticosteroid therapy. METHODS: We did this prospective, open-label, randomised trial at ten hospitals in Italy. Using a concealed computer-generated list, children younger than 18 years with oligoarticular-onset disease were randomly assigned (1:1) to intra-articular corticosteroids alone or in combination with oral methotrexate (15 mg/m(2); maximum 20 mg)...
February 2, 2017: Lancet
https://www.readbyqxmd.com/read/28155828/elbow-arthroplasty-in-patients-with-bleeding-disorders-preliminary-report-of-a-single-centre-experience
#15
Andrzej Leń, Jerzy Mirosław Jaworski, Joanna Zdziarska, Bartłomiej Skotnicki, Bogusław Frańczuk
Spontaneous or traumatic hemorrhages into joints that occur in the course of congenital bleeding disorders due to deficiencies of plasma clotting factors lead to early and extensive damage to joints. Arthropathy in those patients most commonly affects the knee, elbow and ankle. Replacement surgery of the damaged joint is the only effective way to treat such advanced changes. Although arthritis of the elbow is quite common, surgery is rarely undertaken; hence relevant reports in the literature are limited to individual or small groups of cases...
March 23, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28152087/radiological-features-of-experimental-staphylococcal-septic-arthritis-by-micro-computed-tomography-scan
#16
Farah Fatima, Ying Fei, Abukar Ali, Majd Mohammad, Malin C Erlandsson, Maria I Bokarewa, Muhammad Nawaz, Hadi Valadi, Manli Na, Tao Jin
BACKGROUND: Permanent joint dysfunction due to bone destruction occurs in up to 50% of patients with septic arthritis. Recently, imaging technologies such as micro computed tomography (μCT) scan have been widely used for preclinical models of autoimmune joint disorders. However, the radiological features of septic arthritis in mice are still largely unknown. METHODS: NMRI mice were intravenously or intra-articularly inoculated with S. aureus Newman or LS-1 strain...
2017: PloS One
https://www.readbyqxmd.com/read/28143550/spectrum-of-paediatric-rheumatic-diseases-in-nigeria
#17
Babatunde Hakeem Olaosebikan, Olufemi Oladipo Adelowo, Barakat Adeola Animashaun, Richard Oluyinka Akintayo
BACKGROUND: Paediatric rheumatology service in Sub-Sahara African is virtually not available as there is a shortage of paediatric rheumatologists and other rheumatology health professionals. We aim to describe the clinical spectrum and the frequencies of paediatric rheumatic diseases (PRDs) in Lagos State University Teaching Hospital (LASUTH), Lagos, Nigeria. METHODS: This is a retrospective review of patients with PRDs seen over a five year period (March 2010 to February 2016) at the rheumatology clinic and children ward of LASUTH...
January 31, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28132085/tibial-condylar-valgus-osteotomy-tcvo-for-osteoarthritis-of-the-knee-5-year-clinical-and-radiological-results
#18
Ko Chiba, Akihiko Yonekura, Takashi Miyamoto, Makoto Osaki, Goji Chiba
PURPOSE: Tibial condylar valgus osteotomy (TCVO) is a type of opening-wedge high tibial osteotomy for advanced medial knee osteoarthritis (OA) with subluxated lateral joint. We report the concept, the current surgical technique with a locking plate, and the short-term clinical and radiological results of this procedure. METHODS: 11 knees with medial OA and a widened lateral joint were treated by TCVO (KL stage III: 6, IV: 5). In this procedure, by the L-shaped osteotomy from the medial side of the proximal tibia to the intercondylar eminence and the valgus correction, lateralization of the mechanical axis and reduction of the subluxated lateral joint are obtained with early postoperative weight-bearing...
January 28, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28129488/chondrocalcinosis-in-knee-joints-is-associated-with-pain-but-not-with-synovitis-data-from-the-osteoarthritis-initiative
#19
Bobby Kwanghoon Han, Woojin Kim, Jingbo Niu, Shristi Basnyat, Veniamin Barshay, John P Gaughan, Charlene Williams, Sharon L Kolasinski, David T Felson
OBJECTIVE: To evaluate the relationship between chondrocalcinosis and pain or synovitis in knee joints by examining data from the Osteoarthritis Initiative (OAI). METHODS: Data were obtained from the OAI public use data sets. The relationship between chondrocalcinosis on baseline knee radiograph and pain at baseline and at 4 years was examined. Analyses were adjusted for age, gender, body mass index, and Kellgren-Lawrence (KL) grade and the correlation between two knees in a subject was controlled using generalized estimating equations...
January 27, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28129484/perioperative-timing-of-infliximab-and-the-risk-of-serious-infection-after-elective-hip-and-knee-arthroplasty
#20
Michael D George, Joshua F Baker, Jesse Yenchih Hsu, Qufei Wu, Fenglong Xie, Lang Chen, Huifeng Yun, Jeffrey R Curtis
OBJECTIVE: The optimal timing of TNF antagonists before elective surgery is unknown. This study evaluated the association between infliximab timing and serious infection after elective hip or knee arthroplasty. METHODS: A retrospective cohort study evaluated U.S. Medicare patients with rheumatoid arthritis, inflammatory bowel disease, psoriasis, psoriatic arthritis, or ankylosing spondylitis who received infliximab within 6 months of elective knee or hip arthroplasty from 2007-2013...
January 27, 2017: Arthritis Care & Research
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