keyword
https://read.qxmd.com/read/38567043/diagnostic-and-therapeutic-strategies-in-early-onset-scoliosis-a-current-concept-review
#1
REVIEW
Daniel Studer, Carol Claudius Hasler
Substantial advances in the treatment of early onset scoliosis (EOS) over the past two to three decades have resulted in significant improvements in health-related quality of life of affected children. In addition to classifications that address the marked heterogeneity of this patient population, increasing understanding of the natural history of the disease, and new implants and treatment techniques have resulted in innovations unlike any other area of pediatric orthopedics. The growing understanding of the interaction between spinal and thoracic growth, as well as dependent lung maturation, has had a lasting impact on the treatment strategy of this potentially life-threatening disease...
April 2024: Journal of Children's Orthopaedics
https://read.qxmd.com/read/38555113/aud-in-perspective
#2
JOURNAL ARTICLE
Andrea de Bejczy, Giovanni Addolorato, Henri-Jean Aubin, Julien Guiraud, Esa R Korpi, David John Nutt, Katie Witkiewitz, Bo Söderpalm
Alcohol is a major cause of pre-mature death and individual suffering worldwide, and the importance of diagnosing and treating AUD cannot be overstated. Given the global burden and the high attributable factor of alcohol in a vast number of diseases, the need for additional interventions and the development of new medicines is considered a priority by the World Health Organization (WHO). As of today, AUD is severely under-treated with a treatment gap nearing 90%, strikingly higher than that for other psychiatric disorders...
2024: International Review of Neurobiology
https://read.qxmd.com/read/38469079/sleep-quality-and-sleep-deprivation-relationship-with-academic-performance-in-university-students-during-examination-period
#3
JOURNAL ARTICLE
Maria Suardiaz-Muro, Manuel Ortega-Moreno, Miguel Morante-Ruiz, Manuel Monroy, Miguel A Ruiz, Pilar Martín-Plasencia, Antonio Vela-Bueno
The beginning of the university brings together maturational, psychosocial and academic changes that make university students more prone to suffer from insufficient or poor quality sleep, which can negatively influence their academic performance. The period of taking exams is a key part of the academic year. However, there are few studies that analyze sleep during this period of time. Our aim is to study the association of sleep quality and sleep deprivation with academic performance during the examination period...
July 2023: Sleep and Biological Rhythms
https://read.qxmd.com/read/38385867/genetic-background-modulates-the-effect-of-glucocorticoids-on-proliferation-differentiation-and-myelin-formation-of-oligodendrocyte-lineage-cells
#4
JOURNAL ARTICLE
Adrien Gigliotta, Jessica Mingardi, Sarah Cummings, Vida Alikhani, Kalevi Trontti, Alessandro Barbon, Rashmi Kothary, Iiris Hovatta
Anxiety disorders are prevalent mental disorders. Their predisposition involves a combination of genetic and environmental risk factors, such as psychosocial stress. Myelin plasticity was recently associated with chronic stress in several mouse models. Furthermore, we found that changes in both myelin thickness and node of Ranvier morphology after chronic social defeat stress are influenced by the genetic background of the mouse strain. To understand cellular and molecular effects of stress-associated myelin plasticity, we established an oligodendrocyte (OL) model consisting of OL primary cell cultures isolated from the C57BL/6NCrl (B6; innately non-anxious and mostly stress-resilient strain) and DBA/2NCrl (D2; innately anxious and mostly stress-susceptible strain) mice...
February 22, 2024: European Journal of Neuroscience
https://read.qxmd.com/read/38272596/optimizing-glycemic-outcomes-for-children-with-type-1-diabetes
#5
REVIEW
Vickie Wu, Lauryn Choleva, Meredith Wilkes
Changes in physical growth, neurocognitive development, and pubertal maturation are some of the challenges to achieving blood glucose targets in children with type 1 diabetes mellitus. To optimize glycemic outcomes, a comprehensive approach is crucial to address psychosocial needs, expand the use of diabetes technology, and diminish health inequities.
March 2024: Endocrinology and Metabolism Clinics of North America
https://read.qxmd.com/read/38236945/adolescent-contact-lasting-impact-lessons-learned-from-two-longitudinal-studies-spanning-20-years-of-developmental-science-research-with-justice-system-involved-youths
#6
JOURNAL ARTICLE
Elizabeth Cauffman, Marie L Gillespie, Jordan Beardslee, Frank Davis, Maria Hernandez, Tamika Williams
In this article, we summarize key findings from 20 years of research conducted at the intersection of developmental psychology and juvenile justice in the United States. We predominantly examine data from two large-scale, multisite longitudinal studies involving justice-system-involved adolescents-the Pathways to Desistance study and the Crossroads study. Topics of discussion include predictors of offending and desistance from crime; youth outcomes and psychosocial needs; and emerging research, programs, and policy initiatives...
December 2023: Psychological Science in the Public Interest: a Journal of the American Psychological Society
https://read.qxmd.com/read/38222691/tailoring-parenting-styles-and-family-based-interventions-cross-culturally-as-an-effective-prevention-strategy-for-youth-substance-use-a-scoping-review
#7
REVIEW
Ozge C Williams, Sakshi Prasad, Ahmed Ali Khan, Oghenetega Esther Ayisire, Hafsa Naseer, Muhammad Abdullah, Mahrukh Nadeem, Nauman Ashraf, Muhammad Zeeshan
BACKGROUND: The challenge of substance use among youth continues to be a highly concerning public health issue across the globe. The notion that parenting lifestyles and family-based intervention can help in the prevention of adolescent substance use have received robust attention from policy makers, researchers' clinicians and general public, nonetheless, there is scarcity of high quality evidence to support these concepts. OBJECTIVE: To review available literature which assessed the effects of parenting styles and family-based interventions on the prevention of adolescent substance use...
January 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38157733/resting-eeg-correlates-of-neurodevelopment-in-a-socioeconomically-and-linguistically-diverse-sample-of-toddlers-wave-1-of-the-kia-t%C3%A4-mata-pai-best-start-new-zealand-study
#8
JOURNAL ARTICLE
Anne B Arnett, Hayley Guiney, Tugce Bakir-Demir, Anita Trudgen, William Schierding, Vincent Reid, Justin O'Sullivan, Peter Gluckman, Elaine Reese, Richie Poulton
Development of communication and self-regulation skills is fundamental to psychosocial maturation in childhood. The Kia Tīmata Pai Best Start (KTP) longitudinal study aims to promote these skills through interventions delivered at early childcare centers across New Zealand. In addition to evaluating effects of the interventions on behavioral and cognitive outcomes, the study utilizes electroencephalography (EEG) to characterize cortical development in a subsample of participating children. Here, we present results of the baseline resting EEG assessment with 193 children aged 15 to 33 months...
December 26, 2023: Developmental Cognitive Neuroscience
https://read.qxmd.com/read/38105951/the-green-heart-project-objectives-design-and-methods
#9
Aruni Bhatnagar, Rachel Keith, Ray Yeager, Daniel Riggs, Clara Sears, Brent Bucknum, Ted Smith, Daniel Fleischer, Chris Chandler, Kandi L Walker, Joy L Hart, Sanjay Srivastava, Jay Turner, Shesh Rai
The Green Heart Project is a community-based trial to evaluate the effects of increasing greenery on urban environment and community health. The study was initiated in 2018 in a low-to-middle-income mixed-race residential area of nearly 28,000 residents in Louisville, KY. The 4 square mile area was surveyed for land use, population characteristics, and greenness, and assigned to 8 paired clusters of demographically- and environmentally matched "target" (T) and adjacent "control" (C), clusters. Ambient levels of ultrafine particles, ozone, oxides of nitrogen, and environmental noise were measured in each cluster...
December 5, 2023: medRxiv
https://read.qxmd.com/read/38078701/the-brain-gut-and-bladder-health-nexus-a-conceptual-model-linking-stress-and-mental-health-disorders-to-overactive-bladder-in-women
#10
JOURNAL ARTICLE
Ariana L Smith, Amanda Berry, Linda Brubaker, Shayna D Cunningham, Sheila Gahagan, Lisa Kane Low, Margaret Mueller, Siobhan Sutcliffe, Beverly R Williams, Sonya S Brady
OBJECTIVE: A small, but growing literature links stressors and mental health disorders (MHDs) across the life course to overactive bladder (OAB) and urinary incontinence symptoms. Mechanisms by which stressors and MHDs may impact bladder health are not fully understood, limiting novel prevention and treatment efforts. Moreover, potential biopsychosocial mechanisms involving the brain and gut have not been considered in an integrated, comprehensive fashion. METHODS: Members of the prevention of lower urinary tract symptoms Research Consortium developed conceptual models to inform research on biopsychosocial mechanisms through which stress and MDHs may impact bladder health among girls and women, focusing on brain and gut physiology...
December 11, 2023: Neurourology and Urodynamics
https://read.qxmd.com/read/38071516/an-x-ray-of-the-national-mental-health-act-2021-of-nigeria-opportunities-limitations-and-the-way-forward
#11
REVIEW
Yesiru A Kareem, Umar B Musami, Mohammed Y Mahmood, Abdulhakeem Shuaib, Placidus N Ogualili
The Nigerian Mental Health Law originated as a Lunacy ordinance in 1916 and matured into Lunacy Act CAP 524 of the law of Nigeria, 1964. This review of the National Mental Health Act (NMHA) 2021 of Nigeria examines the prospects, challenges, and possible ways forward. This act has a schedule, five parts, fifty-eight sections, and many subsections. It was compared with the WHO Checklist while the limitations were examined with a view to recommending solutions and identifying the tasks ahead. The NMHA 2021 provides for enhancing and regulating Mental Health Services through a Mental health Services Department...
December 4, 2023: West African Journal of Medicine
https://read.qxmd.com/read/38034154/neonatal-abstinence-syndrome-an-insight-over-impact-of-maternal-substance-use
#12
REVIEW
Omkar Dumbhare, Amar Taksande
Neonatal abstinence syndrome (NAS) highlights the intricate interplay between maternal substance use during pregnancy and the challenges neonates face from the distressing global opioid crisis. This comprehensive review captures the multilayered landscape of NAS, encircling its underlying mechanisms, epidemiology, diagnostic intricacies, clinical manifestations, continuing developmental impacts, treatment paradigms, and the crucial role of multidisciplinary care. The core pathophysiology of NAS involves the transplacental passage of addictive substances, activating chemical dependence in the maturing fetus, which is characterized by neurotransmitter dysregulation, neuroadaptations, and receptor sensitization...
October 2023: Curēus
https://read.qxmd.com/read/38030545/utilizing-orthodontic-appliances-to-retain-and-disguise-a-pediatric-maxillary-obturator-throughout-growth
#13
JOURNAL ARTICLE
Michelle K Ruse, Pamela A Lloren, Arthur J Bigsby, Matthew T Harper, Sarah K Y Lee, Olivia M Muller
Unique challenges are encountered when providing an obturator for an adolescent patient. Challenges include the need to modify the obturator throughout growth, engaging the mixed dentition or partially erupted teeth with minimal undercuts, the psychosocial challenges of an actively maturing patient, and the possible need for coincidental orthodontic therapy. This clinical report describes the ongoing rehabilitation of a patient who presented at the age of 10 with a biopsy-confirmed palatal mucoepidermoid carcinoma...
November 28, 2023: Journal of Prosthetic Dentistry
https://read.qxmd.com/read/38027773/food-safety-culture-maturity-and-its-relation-to-company-and-employee-characteristics
#14
JOURNAL ARTICLE
Pauline Spagnoli, Peter Vlerick, Liesbeth Jacxsens
Three facets of food safety culture (FSC) (i.e., food safety management system (FSMS), human-organizational and human-individual building block), were diagnosed through a validated mixed-method assessment in twenty food processing companies. Many underdeveloped dimensions were detected in the FSMS and the human-organizational building block, while the human-individual building block was more mature. It was explored whether company (e.g., company size) and employee characteristics (e.g. leaders vs. non-leaders) are associated with FSC maturity (based on 1410 employee responses) through a cluster analysis and statistical (Mann-Whitney U and Kruskal-Wallis) tests...
November 2023: Heliyon
https://read.qxmd.com/read/37909080/adolescence-is-characterized-by-more-sedentary-behaviour-and-less-physical-activity-even-among-highly-active-forager-farmers
#15
JOURNAL ARTICLE
Ann E Caldwell, Daniel K Cummings, Paul L Hooper, Benjamin C Trumble, Michael Gurven, Jonathan Stieglitz, Helen E Davis, Hillard Kaplan
Over 80% of adolescents worldwide are insufficiently active, posing massive public health and economic challenges. Declining physical activity (PA) and sex differences in PA consistently accompany transitions from childhood to adulthood in post-industrialized populations and are attributed to psychosocial and environmental factors. An overarching evolutionary theoretical framework and data from pre-industrialized populations are lacking. This cross-sectional study tests hypotheses from life history theory, that adolescent PA is inversely related to age, but this association is mediated by Tanner stage, reflecting higher and sex-specific energetic demands for growth and reproductive maturation...
November 8, 2023: Proceedings. Biological Sciences
https://read.qxmd.com/read/37907834/riding-the-tides-directions-in-mental-health-rehabilitation-in-nsw
#16
JOURNAL ARTICLE
Andrew McDonald, Megan Still, Joanne Sommer, Francesca Coniglio
OBJECTIVE: This paper outlines the evolution of mental health rehabilitation in NSW, where allocation of health resources has repeatedly contradicted the policy intention to reorient services from inpatient to community-based services, leaving community rehabilitation the poor and disconnected cousin of inpatient services. The expanding role of community-managed organisations (CMOs) in psychosocial rehabilitation, the introduction of the National Disability Insurance Scheme (NDIS), and emerging service models have helped foster a maturing housing and social care environment, but present reality and the integration of health and social care services remains at a distance from best evidence practice...
October 31, 2023: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://read.qxmd.com/read/37866522/interrogating-consequential-validity-evidence-in-naplex-studies-involving-the-use-of-demographic-variables
#17
REVIEW
Jacqueline E McLaughlin
OBJECTIVE: to review the purpose, methods and discussion of student demographics related to NAPLEX performance; demographic characteristics, significant findings, and related text were extracted from each reviewed article as evidence of consequential validity. FINDINGS: Nine articles met the inclusion criteria. Prior degree attainment (n=8, 88.9%), age (n=6, 66.7%), race/ethnicity (n=6, 66.7%), and sex (n=5, 55.6%) were the most common demographic variables included...
October 20, 2023: American Journal of Pharmaceutical Education
https://read.qxmd.com/read/37843186/biocultural-correlates-of-gross-motor-coordination-in-prepubescent-children-a-cross-sectional-study
#18
JOURNAL ARTICLE
Braulio Patrick da Silva Lima, Bruno Barbosa Giudicelli, Ingrid Kelly Alves Dos Santos Pinheiro, Douglas Henrique Bezerra Santos, Kleberton Carlos Silva Magalhães, Rafael Dos Santos Henrique, Danilo Rodrigues Pereira da Silva, Manuel João Coelho E Silva, Leonardo Gomes de Oliveira Luz
AIM: This study aimed to explore the association of gross motor coordination (GMC) with a matrix of biocultural factors in prepubescent children, taking into account weight status, somatic maturation, sociodemographic variables, and type of school. METHODS: One hundred twenty-nine prepubescent children, of both sexes, aged between 8.00 and 8.99, were assessed for GMC (Körperkoordinationstest Für Kinder - KTK), weight status, biological maturation (predicted mature stature), sex, mother's education level and type of school...
October 16, 2023: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://read.qxmd.com/read/37815245/longitudinal-change-in-mismatch-negativity-mmn-but-not-in-gamma-band-auditory-steady-state-response-assr-is-associated-with-psychological-difficulties-in-adolescence
#19
JOURNAL ARTICLE
Kaori Usui, Kenji Kirihara, Tsuyoshi Araki, Mariko Tada, Daisuke Koshiyama, Mao Fujioka, Ryoichi Nishimura, Shuntaro Ando, Shinsuke Koike, Hiroshi Sugiyama, Toru Shirakawa, Rie Toriyama, Mio Masaoka, Shinya Fujikawa, Kaori Endo, Syudo Yamasaki, Atsushi Nishida, Kiyoto Kasai
Adolescence is a critical period for psychological difficulties. Auditory mismatch negativity (MMN) and gamma-band auditory steady-state response (ASSR) are representative electrophysiological indices that mature during adolescence. However, the longitudinal association between MMN/ASSR and psychological difficulties among adolescents remains unclear. We measured MMN amplitude for duration and frequency changes and ASSR twice in a subsample (n = 67, mean age 13.4 and 16.1 years, respectively) from a large-scale population-based cohort...
October 10, 2023: Cerebral Cortex
https://read.qxmd.com/read/37792948/combining-bioengineered-human-skin-with-bioprinted-cartilage-for-ear-reconstruction
#20
JOURNAL ARTICLE
Dominika Zielinska, Philipp Fisch, Ueli Moehrlen, Sergio Finkielsztein, Thomas Linder, Marcy Zenobi-Wong, Thomas Biedermann, Agnes S Klar
Microtia is a congenital disorder that manifests as a malformation of the external ear leading to psychosocial problems in affected children. Here, we present a tissue-engineered treatment approach based on a bioprinted autologous auricular cartilage construct (EarCartilage) combined with a bioengineered human pigmented and prevascularized dermo-epidermal skin substitute (EarSkin) tested in immunocompromised rats. We confirmed that human-engineered blood capillaries of EarSkin connected to the recipient's vasculature within 1 week, enabling rapid blood perfusion and epidermal maturation...
October 6, 2023: Science Advances
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