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Six minute walk test

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https://www.readbyqxmd.com/read/29201436/therapeutic-benefits-of-phosphodiesterase-5-inhibition-in-chronic-heart-failure-a-meta-analysis
#1
Renato De Vecchis, Arturo Cesaro, Carmelina Ariano
Background: Phosphodiesterase-5 inhibitors (PDE5i) have been shown to be beneficial for patients with pulmonary arterial hypertension. However, several studies would have documented a useful effect of PDE5i even for pulmonary hypertension secondary to left-sided chronic heart failure (CHF). Methods: We performed a meta-analysis including randomized controlled trials (RCTs) which had compared PDE5i (mostly sildenafil) and placebo in CHF patients. Results: Fourteen studies enrolling a total of 928 patients were incorporated in the meta-analysis...
September 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/29191775/agreement-of-different-reference-equations-to-classify-patients-with-copd-as-having-reduced-or-preserved-6mwd
#2
F V C Machado, G W Bisca, A A Morita, A Rodrigues, V S Probst, K C Furlanetto, F Pitta, N A Hernandes
BACKGROUND: Interpretation of the six-minute walk distance (6MWD) is enhanced by using recommended reference equations. Whenever possible, the choice of equation should be region-specific. A potential problem is that different equations for the 6MWD may have been developed for the same population, and it may be complicated to choose the most suitable. OBJECTIVE: To verify the agreement of different reference equations in classifying patients with Chronic Obstructive Pulmonary Disease (COPD) as having reduced or preserved 6MWD...
November 27, 2017: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/29182940/clinical-study-of-optical-coherence-tomography-in-the-diagnosis-of-peripheral-pulmonary-artery-thrombus
#3
Cheng Hong, Fu-Quan Luo, Chun-Li Liu, Nan-Shan Zhong, Jie-Ying Li, Wei Wang
BACKGROUND: Peripheral pulmonary artery thrombus (PPT) is common in the clinic. However, due to the lack of an ideal diagnostic tool, PPT cannot be quickly diagnosed and effectively treated at present. Optical coherence tomography (OCT) is a new intravascular imaging technique that is characterized by high image resolution. This technique is suitable for small vessel imaging and has the ability to distinguish red and white thrombi. OBJECTIVE: This study aimed to evaluate the value of OCT in the diagnosis of PPT and in identifying the nature of thrombi by comparing the difference in sensitivity between OCT and selective pulmonary angiography (SPA)...
October 28, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29173609/effects-of-patent-foramen-ovale-closure-on-obstructive-sleep-apnea-syndrome-pcosa-study
#4
Stephen P Hoole, Jules Hernández-Sánchez, William R Davies, Duncan C McNab, Patrick A Calvert, Bushra S Rana, Leonard M Shapiro, Michael G Davies
BACKGROUND: Previous studies have shown a higher prevalence of patent foramen ovale (PFO) in patients with obstructive sleep apnea syndrome (OSAS). Right to left shunting through a PFO may be encouraged by the respiratory physiology of OSAS, contributing to the disease pathophysiology. We assessed whether PFO closure would improve respiratory polygraphy parameters compared with baseline measurements in patients with OSAS. METHODS: Twenty-six patients with newly diagnosed OSAS and a moderate-large PFO (prevalence, 18% of 143 patients screened) were referred for PFO closure...
December 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29170035/titrating-oxygen-requirements-during-exercise-evaluation-of-a-standardized-single-walk-test-protocol
#5
Coral X Giovacchini, Anne M Mathews, Brian R Lawlor, Neil R MacIntyre
BACKGROUND: Oxygen supplementation for exercise induced hypoxemia is a common clinical practice that improves exercise tolerance. However, we know of no standardized exercise oxygen titration protocol utilizing a single walk test. We report herein our experience with a protocol developed in our laboratory. METHODS: Our protocol is based on the six-minute walk test (6MWT). Pulse oximetry readings (SpO2) are monitored and supplemental oxygen is added in 2L/min increments to keep SpO2>88%...
November 20, 2017: Chest
https://www.readbyqxmd.com/read/29138051/sarcopenia-in-peripheral-arterial-disease-prevalence-and-impact-on-functional-status
#6
Odessa Addison, Steven J Prior, Rishi Kundi, Monica C Serra, Leslie I Katzel, Andrew W Gardner, Alice S Ryan
OBJECTIVES: To determine the prevalence of sarcopenia in older men with peripheral arterial disease (PAD) and to compare to a subset of the group to age, race, sex, and body mass index (BMI)-matched non-PAD control counterparts. We also sought to compare the functional status of those with PAD with and without sarcopenia. DESIGN: Cohort study. SETTING: A Veterans Affairs medical center. PARTICIPANTS: Sedentary, community dwelling men age 50+ years with a confirmed diagnosis of PAD (N=108; 44% black; BMI 27...
November 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29135399/-investigation-of-parameters-related-to-prognosis-in-diffuse-parenchymal-lung-diseases-prognosis-in-interstitial-lung-diseases
#7
Coşkun Canıvar, Züleyha Bingöl, Zeki Kılıçaslan, Tülin Çağatay, N Gülfer Okumuş
Introduction: Parameters related to prognosis in diffuse parenchymal lung disease (DPLD) have a decisive influence on treatment and follow-up processes. We aimed to define baseline characteristics and factors that effect the mortality of the group of patients with DPLD and to determine distinctions between subgroups. Materials and Methods: Demographic characteristics, complaints, comorbidity, treatment, pulmonary function tests, echocardiographic findings, six minute walking test (6MWT), arterial blood gases analysis, radiological findings and survival time were collected from outpatient clinics database...
September 2017: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/29131814/effects-of-an-exercise-protocol-for-improving-handgrip-strength-and-walking-speed-on-cognitive-function-in-patients-with-chronic-stroke
#8
Jaeeun Kim, Jongeun Yim
BACKGROUND Handgrip strength and walking speed predict and influence cognitive function. We aimed to investigate an exercise protocol for improving handgrip strength and walking speed, applied to patients with chronic stroke who had cognitive function disorder. MATERIAL AND METHODS Twenty-nine patients with cognitive function disorder participated in this study, and were randomly divided into one of two groups: exercise group (n=14) and control group (n=15). Both groups underwent conventional physical therapy for 60 minutes per day...
November 13, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29131689/do-pedometers-with-or-without-education-on-exercise-increase-functional-walking-capacity-and-physical-activity-level-in-adolescents-with-juvenile-idiopathic-arthritis
#9
Jill Blitz, Sara M Stern, Katherine Marzan
To evaluate the impact of pedometer use on the physical activity (PA) and functional walking capacity (FWC) of adolescents with juvenile idiopathic arthritis (JIA) and lower extremity (LE) involvement. Twenty-seven adolescents, aged 11-19 years with JIA and LE involvement, participated in the three-phase pedometer study that introduced the use of a pedometer and an education seminar at 6 weeks. Measurements were taken at the baseline first visit and at weeks 6, 12, and 20. The primary outcome measure was the 6-minute walk test (6MWT)...
November 13, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29127543/self-efficacy-pain-and-quadriceps-capacity-at-baseline-predict-changes-in-mobility-performance-over-2%C3%A2-years-in-women-with-knee-osteoarthritis
#10
Nicholas M Brisson, Anthony A Gatti, Paul W Stratford, Monica R Maly
This study examined the extent to which baseline measures of quadriceps strength, quadriceps power, knee pain and self-efficacy for functional tasks, and their interactions, predicted 2-year changes in mobility performance (walking, stair ascent, stair descent) in women with knee osteoarthritis. We hypothesized that lesser strength, power and self-efficacy, and higher pain at baseline would each be independently associated with reduced mobility over 2 years, and each of pain and self-efficacy would interact with strength and power in predicting 2-year change in stair-climbing performance...
November 10, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29113572/effects-of-an-individual-12-week-community-located-start-to-run-program-on-physical-capacity-walking-fatigue-cognitive-function-brain-volumes-and-structures-in-persons-with-multiple-sclerosis
#11
Peter Feys, Lousin Moumdjian, Florian Van Halewyck, Inez Wens, Bert O Eijnde, Bart Van Wijmeersch, Veronica Popescu, Paul Van Asch
BACKGROUND: Exercise therapy studies in persons with multiple sclerosis (pwMS) primarily focused on motor outcomes in mid disease stage, while cognitive function and neural correlates were only limitedly addressed. OBJECTIVES: This pragmatic randomized controlled study investigated the effects of a remotely supervised community-located "start-to-run" program on physical and cognitive function, fatigue, quality of life, brain volume, and connectivity. METHOD: In all, 42 pwMS were randomized to either experimental (EXP) or waiting list control (WLC) group...
November 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29111007/performed-and-perceived-walking-ability-in-relation-to-the-expanded-disability-status-scale-in-persons-with-multiple-sclerosis
#12
D Langeskov-Christensen, P Feys, I Baert, M Riemenschneider, E Stenager, U Dalgas
BACKGROUND: The severity of walking impairment in persons with multiple sclerosis (pwMS) at different levels on the expanded disability status scale (EDSS) is unclear. Furthermore, it is unclear if the EDSS is differently related to performed- and perceived walking capacity tests. AIMS: To quantify walking impairment and perceived impact of MS on walking according to EDSS scores and to examine the relations between these parameters in pwMS. METHODS: EDSS was collected by neurologists and walking was assessed by the timed 25ft walk test (T25FWT), two minute walk test (2MWT), six minute walk test (6MWT) and the 12-item MS walking scale (MSWS-12) in 474 PwMS with mild (EDSS 1-4: n=200) to moderate (EDSS 4...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29104725/effect-of-multicomponent-training-on-blood-pressure-nitric-oxide-redox-status-and-physical-fitness-in-older-adult-women-influence-of-endothelial-nitric-oxide-synthase-nos3-haplotypes
#13
Atila Alexandre Trapé, Elisangela Aparecida da Silva Lizzi, Thiago Correa Porto Gonçalves, Jhennyfer Aline Lima Rodrigues, Simone Sakagute Tavares, Riccardo Lacchini, Lucas Cezar Pinheiro, Graziele Cristina Ferreira, José Eduardo Tanus-Santos, Paula Payão Ovídio, Alceu Afonso Jordão, André Mourão Jacomini, Anderson Saranz Zago, Carlos Roberto Bueno Júnior
The purpose of this study was to verify the influence of the genotype or haplotype (interaction) of the NOS3 polymorphisms [-786T>C, 894G>T (Glu298Asp), and intron 4b/a] on the response to multicomponent training (various capacities and motor skills) on blood pressure (BP), nitrite concentration, redox status, and physical fitness in older adult women. The sample consisted of 52 participants, who underwent body mass index and BP assessments. Physical fitness was evaluated by six-minute walk, elbow flexion, and sit and stand up tests...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29104679/physiotherapy-in-patients-with-chronic-obstructive-pulmonary-disease
#14
Antoaneta Dimitrova, Nikolay Izov, Ivan Maznev, Dance Vasileva, Milena Nikolova
BACKGROUND: Physiotherapy is an essential for the treatment of patients with chronic respiratory non-inflammatory diseases especially for chronic obstructive pulmonary disease (COPD). AIM: To assess the effect of six months physiotherapy (PT) program on functional status in patients with COPD. MATERIAL AND METHODS: The patients were divided into two groups according to the severity of the disease. Group A included 33 patients (mean age 68...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29103048/treadmill-training-with-cues-and-feedback-improves-gait-in-people-with-more-advanced-parkinson-s-disease
#15
Valeria Studer, Roberto Maestri, Ilaria Clerici, Letizia Spina, Ilaria Zivi, Davide Ferrazzoli, Giuseppe Frazzitta
BACKGROUND: Gait disturbances in Parkinson's disease (PD) are highly disabling and poorly responsive to drugs, especially in advanced stages. While the efficacy of a treadmill training based on external feedback and cues (treadmill-plus) on gait disturbances in early PD stages is demonstrated, no definitive evidence exists about advanced stages. OBJECTIVE: We aimed to evaluate the feasibility and the effects of a treadmill-plus training on gait disturbances in advanced PD...
2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/29100885/a-phase-ii-clinical-trial-of-low-dose-inhaled-carbon-monoxide-in-idiopathic-pulmonary-fibrosis
#16
Ivan O Rosas, Hilary J Goldberg, Harold R Collard, Souheil El-Chemaly, Kevin Flaherty, Gary M Hunninghake, Joseph A Lasky, David J Lederer, Roberto Machado, Fernando J Martinez, Rie Maurer, Danielle Teller, Imre Noth, Elizabeth Peters, Ganesh Raghu, Joe G N Garcia, Augustine M K Choi
BACKGROUND: Preclinical studies have demonstrated that low-dose carbon monoxide (CO) can abrogate experimental lung fibrosis. To test the therapeutic role of inhaled CO, we designed a clinical study in patients with idiopathic pulmonary fibrosis (IPF). METHODS: We conducted a multicenter, phase IIa, double-blinded, sham-controlled, clinical trial. Patients with IPF were randomized to treatment with inhaled CO at 100 to 200 parts per million or to inhaled 21% oxygen for 2 h daily, twice weekly, for 12 weeks...
October 31, 2017: Chest
https://www.readbyqxmd.com/read/29100670/donor-site-morbidity-after-vascularized-fibula-free-flap-gait-analysis-during-prolonged-walk-conditions
#17
N Hadouiri, D Feuvrier, J Pauchot, P Decavel, Y Sagawa
The aim of this study was to determine the effect of vascularized fibula free flap (VFFF) harvest on gait variables during the six-minute walk test (6MWT). Eleven patients who had undergone VFFF harvest and 11 healthy peers participated in this case-control study. The main evaluation consisted of the collection of gait variables using the GAITRite system during three periods of the 6MWT: beginning (0-1min), middle (2:30-3:30min), and end (5-6min). The 6MWT was significantly shorter in the VFFF group than in the reference group (-31%, P<0...
October 31, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29081849/physical-function-and-health-related-quality-of-life-in-young-adults-with-unilateral-congenital-lower-limb-deficiencies
#18
T S Kaastad, A T Tveter, H Steen, I Holm
PURPOSE: The primary aim was to examine if there were differences in physical function and health-related quality of life (HRQoL) between young adults (18 to 35 years) with unilateral congenital lower-limb deficiency (CLLD) who had been surgically lengthened (Surg) and those using lengthening prostheses (Pros). Second, we wanted to compare their health status with an age- and gender-matched reference group (Ref) without CLLD. METHODS: Cross-sectional study including a study-specific questionnaire, clinical examination, two field tests evaluating physical function (the six-minute walk test and the Stair test) and HRQoL questionnaires (Short Form (SF)-36 and EuroQol (EQ)-5D-3L)...
October 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29080964/effects-of-an-individualized-home-based-unsupervised-aerobic-training-on-body-composition-and-physiological-parameters-in-obese-adults-are-independent-of-gender
#19
G P Emerenziani, M C Gallotta, S Migliaccio, D Ferrari, E A Greco, F J Saavedra, S Iazzoni, A Aversa, L M Donini, A Lenzi, C Baldari, L Guidetti
PURPOSE: Evaluation of the effects of an individualized home-based unsupervised aerobic training on body composition, physical and physiological parameters in female and male obese adults. METHODS: Two hundred and twenty obese adults (age 47.9 ± 12.4 years; BMI 38.0 ± 7.2 kg/m(2)) entered the 4-month training program. Body composition, physiological and functional capacities were assessed pre- and post-intervention. All subjects were requested to perform unsupervised aerobic training with the intensity based on heart rate, walking speed and OMNI-RPE score corresponding to the individual ventilatory threshold for at least 5 days/week...
October 28, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29076824/preliminary-results-from-a-nationwide-adult-cardiology-perspective-for-pulmonary-hypertension-registry-on-clinical-outcome-and-survival-in-pulmonary-hypertension-groups-simurg
#20
Cihangir Kaymaz, Bülent Mutlu, M Serdar Küçükoğlu, Barış Kaya, Bahri Akdeniz, Burçak Kılıçkıran Avcı, Enbiya Aksakal, Mehmet Akbulut, Zehra Atılgan Arıtürk, Sümeyye Güllülü, Gülten Aydoğdu Taçoy, Meral Kayıkçıoğlu, Sanem Nalbantgil, Cihan Örem, Hatice Betül Erer, Murat Yüce, Necip Ermiş, Omaç Tüfekçioğlu, Mesut Demir, Mehmet Birhan Yılmaz, Mehmet Güngör Kaya, Hakan Kültürsay, Zeki Öngen, Lale Tokgözoğlu
OBJECTIVE: The present study was designed to evaluate the characteristics of pulmonary hypertension (PH) and adult cardiology practice patterns for PH in our country. METHODS: We evaluated preliminary survey data of 1501 patients with PH (females, 69%; age, 44.8±5.45) from 20 adult cardiology centers (AdCCs). RESULTS: The average experience of AdCCs in diagnosing and treating patients with PH was 8.5±3.7 years. Pulmonary arterial hypertension (PAH) was the most frequent group (69%) followed by group 4 PH (19%), group 3 PH (8%), and combined pre- and post-capillary PH (4%)...
October 2017: Anatolian Journal of Cardiology
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