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Six minute walk test

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https://www.readbyqxmd.com/read/28805026/correlation-of-6-minute-walk-test-with-left-ventricular-function-and-quality-of-life-in-heart-failure-due-to-chagas-disease
#1
Mayara da Costa Chambela, Mauro Felippe Felix Mediano, Roberto Rodrigues Ferreira, André Miguel Japiassú, Mariana Caldas Waghabi, Gilberto Marcelo Sperandio da Silva, Roberto Magalhães Saraiva
OBJECTIVES: To evaluate the correlation of the total distance walked during the six-minute walk test (6-MWT) with left ventricular function and quality of life in patients with Chagas Disease (ChD) complicated by heart failure. METHODS: This cross-sectional study of adult patients with ChD and heart failure diagnosed based on Framingham criteria. 6MWT was performed following international guidelines. New York Heart Association functional class, brain natriuretic peptide (BNP) serum levels, echocardiographic parameters, and quality of life (SF-36 and MLHFQ questionnaires) were determined and their correlation with the distance covered at the 6MWT was tested...
August 14, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28799458/effects-of-an-unsupervised-pedometer-based-physical-activity-program-on-daily-steps-of-adults-with-moderate-to-severe-asthma-a-randomized-controlled-trial
#2
Cristina Martins Coelho, Maycon Moura Reboredo, Felipe Martins Valle, Carla Malaguti, Larissa Almeida Campos, Lucas Mendes Nascimento, Erich Vidal Carvalho, Júlio César Abreu Oliveira, Bruno Valle Pinheiro
Supervised exercise has shown benefits for subjects with asthma, but little is known about the effectiveness of unsupervised physical activity on this population. We investigated the effects of a 12-week unsupervised pedometer-based physical activity program on daily steps and on clinical and psychological parameters of adults with asthma. Clinically stable adults with moderate to severe asthma were encouraged to take daily 30-minute walks and were randomized to pedometer and control groups. The pedometer group received pedometers and individualized daily step targets...
August 11, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28764220/to-evaluate-the-change-in-brain-natriuretic-peptide-levels-in-outpatients-with-ischemic-cardiomyopathy-and-its-association-with-functional-capacity-a-pilot-study
#3
Amarapalli Jayachandra, Vivek Aggarwal
INTRODUCTION: Literature is sparse on the clinical correlation of six minute walk test (6MWT) and Brain Natriuretic Peptide (BNP) levels in ischemic Cardiomyopathy (Ischemic CMP) patients. New York Heart Association (NYHA) classification is most commonly used for functional assessment of Heart Failure (HF), which is very subjective. This limitation is overcome by 6MWT which has prognostic significance in addition to assessment of level of functional impairment. Serum BNP correlate with clinical severity of HF as assessed by NYHA class...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28760151/pureair-protocol-randomized-controlled-trial-of-intensive-pulmonary-rehabilitation-versus-standard-care-in-patients-undergoing-surgical-resection-for-lung-cancer
#4
Stefania Fugazzaro, Stefania Costi, Carlotta Mainini, Besa Kopliku, Cristian Rapicetta, Roberto Piro, Roberta Bardelli, Patricia Filipa Sobral Rebelo, Carla Galeone, Giorgio Sgarbi, Filippo Lococo, Massimiliano Paci, Tommaso Ricchetti, Silvio Cavuto, Domenico Franco Merlo, Sara Tenconi
BACKGROUND: Non-small cell lung cancer is the most common type of lung cancer. Surgery is proven to be the most effective treatment in early stages, despite its potential impact on quality of life. Pulmonary rehabilitation, either before or after surgery, is associated with reduced morbidity related symptoms and improved exercise capacity, lung function and quality of life. METHODS: We describe the study protocol for the open-label randomized controlled trial we are conducting on patients affected by primary lung cancer (stages I-II) eligible for surgical treatment...
July 31, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28750180/association-between-inspiratory-muscle-weakness-and-slowed-oxygen-uptake-kinetics-in-patients-with-chronic-obstructive-pulmonary-disease
#5
Andiara Wolpat, Francisco V Lima, Fabiola M Silva, Micheli Tochetto, Andressa Freitas, Tatiane Grandi, Leonardo Rodrigues, Verônica Paiva, Gerson Cipriano, Adriana M Chiappa, Julio Zago, Gaspar R Chiappa
INTRODUCTION: Patients with chronic obstructive pulmonary disease (COPD) may have poor inspiratory muscle function, which reduces minute and alveolar ventilation, leading to increased hypoxemia and slow pulmonary oxygen uptake ( O2) kinetics. However, little is known about the effect of inspiratory muscle weakness (IMW) on oxygen uptake kinetics in patients with COPD. Thus, we tested the hypothesis that COPD patients with IMW have slowed O2 kinetics. METHODS: An observational study was conducted including COPD patients with moderate to severe airflow limitation and a history of intolerance to exercise...
July 27, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28746527/sleep-disordered-breathing-in-patients-with-copd-and-mild-hypoxemia-prevalence-and-predictive-variables
#6
José Laerte Rodrigues Silva, Marcus Barreto Conde, Krislainy de Sousa Corrêa, Helena Rabahi, Arthur Alves Rocha, Marcelo Fouad Rabahi
Objective: To infer the prevalence and variables predictive of isolated nocturnal hypoxemia and obstructive sleep apnea (OSA) in patients with COPD and mild hypoxemia. Methods: This was a cross-sectional study involving clinically stable COPD outpatients with mild hypoxemia (oxygen saturation = 90-94%) at a clinical center specializing in respiratory diseases, located in the city of Goiânia, Brazil. The patients underwent clinical evaluation, spirometry, polysomnography, echocardiography, arterial blood gas analysis, six-minute walk test assessment, and chest X-ray...
May 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28745141/comparison-of-the-long-term-reproducibility-of-the-walk-test-and-of-exercise-peak-oxygen-consumption-in-patients-with-preserved-exercise-capacity
#7
Zainab Raissuni, Gerald Roul
Short-term and long-term reproducibility of the cardiopulmonary (CPX) exercise test have been established. Though short and mid-term reproducibility of the walk test has been ascertained, this was not extensively done for the long-term reproducibility. The aim of the study was to examine the long-term reproducibility of distance walked in an allotted time and to check the stability of the relationship between walked distance and exercise peak VO2 (pVO2). METHODS: Forty six subjects (33 men; 57 ± 14 years), referred for functional capacity assessment, were studied twice by CPX and walking test...
July 26, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28740630/safety-and-effect-of-high-dose-allopurinol-in-patients-with-severe-left-ventricular-systolic-dysfunction
#8
Mohammad Mostafa Ansari-Ramandi, Majid Maleki, Azin Alizadehasl, Ahmad Amin, Sepideh Taghavi, Mohammad Javad Alemzadeh-Ansari, Ali Kazem Moussavi, Nasim Naderi
Introduction: Allopurinol used in the treatment of gout has been shown to improve the vascular endothelial dysfunction and reduce the dysfunction of the failing heart. This study was done to evaluate the effect and safety of allopurinol in non-hyperuricemic patients with chronic severe left ventricular (LV) dysfunction. Methods: In this study, 35 consecutive cases of non-hyperuricemic patients with chronic heart failure who had severe LV systolic dysfunction (ejection fraction of less than 35%) and were on optimal guideline directed medical therapies for at least 3 months were included...
2017: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/28735720/a-randomized-controlled-trial-to-examine-the-impact-of-aquatic-exercise-training-on-functional-capacity-balance-and-perceptions-of-fatigue-in-female-patients-with-multiple-sclerosis
#9
Mehdi Kargarfard, Ardalan Shariat, Lee Ingle, Joshua A Cleland, Mina Kargarfard
OBJECTIVE: To assess the effects of 8-weeks aquatic exercise training program on functional capacity, balance, and perceptions of fatigue in women with multiple sclerosis (MS). DESIGN: A randomized controlled design. SETTING: Referral center of a multiple sclerosis society. PARTICIPANTS: Women (age: 36.4 ±8.2) diagnosed with relapsing-remitting (RR-type) MS. After undergoing baseline testing by a neurologist, participants were allocated to either an intervention (aquatic training program) or a control group...
July 20, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28734576/predictive-validity-analysis-of-six-reference-equations-for-the-6-minute-walk-test-in-healthy-brazilian-men-a-cross-sectional-study
#10
Alexandher Negreiros, Rosimeire Simprini Padula, Rosane Andrea Bretas Bernardes, Mônica Vasconcelos de Moraes, Raquel Simoni Pires, Luciana Dias Chiavegato
BACKGROUND: The six-minute walk test (6MWT) is an important tool for evaluating functional capacity and exercise tolerance. The reference equations for the 6MWT in healthy subjects were established on the basis of American and European populations, but reference equations have been proposed with different variables for the Brazilian population. OBJECTIVE: To analyze the predictive validity of six reference equations for the six-minute walking distance (6MWD) in healthy adult men...
July 4, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28732757/multimodal-exercise-training-in-multiple-sclerosis-a-randomized-controlled-trial-in-persons-with-substantial-mobility-disability
#11
Brian M Sandroff, Rachel E Bollaert, Lara A Pilutti, Melissa L Peterson, Tracy Baynard, Bo Fernhall, Edward McAuley, Robert W Motl
BACKGROUND: Mobility disability is a common, debilitating feature of multiple sclerosis (MS). Exercise training has been identified as an approach to improve MS-related mobility disability. However, exercise randomized controlled trials (RCTs) on mobility in MS have generally not selectively targeted those with the onset of irreversible mobility disability. OBJECTIVES: The current multi-site RCT compared the efficacy of 6-months of supervised, multimodal exercise training with an active control condition for improving mobility, gait, physical fitness, and cognitive outcomes in persons with substantial MS-related mobility disability...
July 19, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28716522/exercise-individualized-by-trimpi-method-reduces-arterial-stiffness-in-early-onset-type-2-diabetic-patients-a-randomized-controlled-trial-with-aerobic-interval-training
#12
Alfonso Bellia, Ferdinando Iellamo, Elisa De Carli, Aikaterini Andreadi, Elvira Padua, Mauro Lombardo, Giuseppe Annino, Francesca Campoli, Sara Tartaglione, Stefano D'Ottavio, David Della-Morte, Davide Lauro
BACKGROUND: Arterial stiffness (AS) and baroreflex sensitivity (BRS) are subclinical markers of vascular diseases in type 2 diabetes (T2D). We evaluated the effects of aerobic interval training (AIT), with loads prescribed according to individual heart rate and lactate profiling obtained during a baseline treadmill test (TRIMPi method), on AS and BRS in patients with early-onset T2D without cardiovascular complications. POPULATION STUDY AND METHODS: Twenty-two sedentary overweight T2D patients (aged 57±7years) were randomized to 12-weeks open-label of supervised AIT by TRIMPi (n=8) or unsupervised physical activity as per usual care (SOC) (n=11)...
June 17, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28679400/the-effectiveness-of-the-use-of-a-digital-activity-coaching-system-in-addition-to-a-two-week-home-based-exercise-program-in-patients-after-total-knee-arthroplasty-study-protocol-for-a-randomized-controlled-trial
#13
Karen E M Harmelink, A V C M Zeegers, Thijs M Tönis, Wim Hullegie, Maria W G Nijhuis-van der Sanden, J Bart Staal
BACKGROUND: There is consistent evidence that supervised programs are not superior to home-based programs after total knee arthroplasty (TKA), especially in patients without complications. Home-based exercise programs are effective, but we hypothesize that their effectiveness can be improved by increasing the adherence to physical therapy advice to reach an adequate exercise level during the program and thereafter. Our hypothesis is that an activity coaching system (accelerometer-based activity sensor), alongside a home-based exercise program, will increase adherence to exercises and the activity level, thereby improving physical functioning and recovery...
July 5, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28675070/validity-of-heart-rate-measurements-by-the-garmin-forerunner-225-at-different-walking-intensities
#14
Jomme Claes, Roselien Buys, Andrea Avila, Dewar Finlay, Alan Kennedy, Daniel Guldenring, Werner Budts, Véronique Cornelissen
The accuracy of wrist worn heart rate monitors based on photoplethysmography (PPG) is not fully clinically accepted. Therefore, we aimed to validate heart rate measurements of a commercially available PPG heart rate monitor, i.e. the Garmin Forerunner(®) 225. Twelve healthy volunteers (six women; mean age: 28 years) performed a treadmill protocol consisting of: five minutes sitting, five minutes standing, 10 minutes walking at 4 km/h, 10 minutes walking at a gradient of 5% and intensity of 4-6 metabolic equivalents (METs), 10 minutes walking at a gradient of 8% and intensity of seven METs or more...
July 4, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/28667653/occurrence-of-bronchial-anthracofibrosis-in-respiratory-symptomatics-with-exposure-to-biomass-fuel-smoke
#15
Vikas Pilaniya, Shekhar Kunal, Ashok Shah
INTRODUCTION: Bronchial anthracofibrosis (BAF), confirmed bronchoscopically, is characterised by bluish-black mucosal pigmentation and distortion/narrowing of the bronchus. We investigated the occurrence of BAF in respiratory symptomatics with biomass fuel smoke exposure and evaluated its clinico-radiological attributes and impact on functional status. MATERIAL AND METHODS: Of the eighty subjects evaluated, 60 consented for fiberoptic bronchoscopy (FOB). All 60 subjects also underwent chest radiography, high resolution computed tomography (HRCT) of the thorax, complete pulmonary function testing including diffusion capacity and six-minute-walk test...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28659856/do-patients-with-multiple-sclerosis-derive-more-benefit-from-robot-assisted-gait-training-compared-with-conventional-walking-therapy-on-motor-function-a-meta-analysis
#16
Xiao Xie, Hao Sun, Qing Zeng, Pengcheng Lu, Yijin Zhao, Tao Fan, Guozhi Huang
OBJECTIVE: To determine whether robot-assisted gait training (RAGT) is more effective in improving mobility, endurance, gait performance, and balance in patients with multiple sclerosis (MS) compared with conventional walking rehabilitation treatment (CWT). DATA SOURCES: Sources included the Cochrane Library, PubMed, Embase, and Science Direct databases. REVIEW METHOD: All possible articles were retrieved by two independent investigators and relevant articles were gathered...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28647467/reliability-and-measurement-error-of-the-osteoarthritis-research-society-international-oarsi-recommended-performance-based-tests-of-physical-function-in-people-with-hip-and-knee-osteoarthritis
#17
F Dobson, R S Hinman, M Hall, C J Marshall, T Sayer, C Anderson, N Newcomb, P W Stratford, K L Bennell
OBJECTIVE: To estimate the reliability and measurement error of performance-based tests of physical function recommended by the Osteoarthritis Research Society International (OARSI) in people with hip and/or knee osteoarthritis (OA). DESIGN: Prospective repeated measures between independent raters within a session and within-rater over a week interval. Relative reliability was estimated for 51 people with hip and/or knee OA (mean age 64.5 years, standard deviation (SD) 6...
June 22, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28646245/six-minute-walk-test-as-a-predictor-of-diagnosis-disease-severity-and-clinical-outcomes-in-scleroderma-associated-pulmonary-hypertension-the-dibosa-study
#18
Abhishek Gadre, Christian Ghattas, Xiaozhen Han, Xiaofeng Wang, Omar Minai, Kristin B Highland
BACKGROUND: Pulmonary hypertension (PH) is a common complication of scleroderma (SSc) and is a leading cause of morbidity and mortality. OBJECTIVES: To explore the utility of the 6MWT in the prediction of SSc-PH and to assess its prognostic implications. METHODS: A retrospective review of SSc patients from 2003 to 2013, with 6MWT and echocardiogram (n = 286), was conducted. Presence of PH was defined by right heart catheterization. Patients were randomized into development and validation cohorts...
June 23, 2017: Lung
https://www.readbyqxmd.com/read/28643370/developing-a-natural-history-progression-model-for-duchenne-muscular-dystrophy-using-the-six-minute-walk-test
#19
Lora Hamuro, Phyllis Chan, Giridhar Tirucherai, Malaz AbuTarif
The six minute walk test (6MWT) is used as a clinical endpoint to evaluate drug efficacy in Duchenne Muscular Dystrophy (DMD) trials. A model was developed using digitized 6MWT data that estimated two slopes and two intercepts to characterize 6MWT improvement during development and 6MWT decline. Mean baseline 6MWT was 362 (± 87) meters. The model predicted an improvement at a rate of 20 meter/year (9.4-30, 95% confidence interval (CI)) up until 10 years old (6.78-13.1, 95% CI), and then decline at a rate of 85 meter/year (72-98, 95% CI)...
June 23, 2017: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/28639841/effects-of-a-mindfulness-based-intervention-on-symptoms-and-signs-in-chronic-heart-failure-a-feasibility-study
#20
Jonna Norman, Michael Fu, Inger Ekman, Lena Björck, Kristin Falk
AIMS: Despite treatment recommended by guidelines, many patients with chronic heart failure remain symptomatic. Evidence is accumulating that mindfulness-based interventions (MBIs) have beneficial psychological and physiological effects. The aim of this study was to explore the feasibility of MBI on symptoms and signs in patients with chronic heart failure in outpatient clinical settings. METHODS: A prospective feasibility study. Fifty stable but symptomatic patients with chronic heart failure, despite optimized guideline-recommended treatment, were enrolled at baseline...
June 1, 2017: European Journal of Cardiovascular Nursing
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