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https://www.readbyqxmd.com/read/29789896/an-offline-technique-to-evaluate-residual-motion-of-the-diaphragm-during-deep-inspiratory-breath-hold-from-cone-beam-ct-datasets
#1
Manuel Blessing, Julian Hofmann, Lena Vogel, Judit Boda-Heggemann, Frank Lohr, Frederik Wenz, Florian Stieler, Anna Simeonova-Chergou
PURPOSE: In radiation therapy, the computer-assisted deep inspiration breath-hold (DIBH) technique is one approach to deal with respiratory motion of tumors in the lung, liver, or upper abdomen. However, inter- and intra-breath-hold deviations from an optimal static tumor position might occur. A novel method is presented to noninvasively measure the diaphragm position and thus estimate its residual deviation (as surrogate for the tumor position) based on cone-beam computed tomography (CBCT) projection data using active breathing control during acquisition...
May 22, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29773446/effects-of-preparatory-coaching-and-home-practice-for-deep-inspiration-breath-hold-on-cardiac-dose-for-left-breast-radiation-therapy
#2
A Kim, A M Kalet, N Cao, D S Hippe, L C Fang, L Young, J Meyer, E V Lang, N A Mayr
AIMS: Deep inspiration breath hold (DIBH) reduces cardiac radiation exposure by creating cardiac-chest wall separation in breast cancer radiotherapy. DIBH requires sustaining chest wall expansion for up to 40 s and involves complex co-ordination of thoraco-abdominal muscles, which may not be intuitive to patients. We investigated the effect of in-advance preparatory DIBH coaching and home practice on cardiac doses. MATERIALS AND METHODS: Successive patients from 1 February 2015 to 31 December 2016 with left-sided breast cancer who underwent tangential field radiotherapy utilising the DIBH technique were included...
May 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29761316/impact-of-visual-feedback-on-dose-volume-histograms-for-organs-at-risk-in-postoperative-radiotherapy-with-deep-inspiration-breath-holding-for-patients-treated-with-breast-conserving-therapy-a-planning-study
#3
Keiko Nemoto Murofushi, Masaru Nakajima, Tetsuya Tomita, Minako Sumi, Yasuo Yoshioka, Masahiko Oguchi, Hideyuki Sakurai
BACKGROUND: We evaluated the effectiveness of visual feedback (VF) on radiotherapy with deep inspiration breath-holding (DIBH), and reviewed the dose for organs at risk (OARs). METHODS: Respiratory motions during DIBH for 15 s were monitored during planning computed tomography (CT)-scanning and simulation for 40 patients after breast-conserving surgery from June 2007 to February 2008. For 22 of 40 patients, a goggle-type liquid crystal display monitor was used for VF...
May 14, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29755846/repeatability-of-fdg-pet-ct-metrics-assessed-in-free-breathing-and-deep-inspiration-breath-hold-in-lung-cancer-patients
#4
Lotte Nygård, Marianne C Aznar, Barbara M Fischer, Gitte F Persson, Charlotte B Christensen, Flemming L Andersen, Mirjana Josipovic, Seppo W Langer, Andreas Kjær, Ivan R Vogelius, Søren M Bentzen
We measured the repeatability of FDG PET/CT uptake metrics when acquiring scans in free breathing (FB) conditions compared with deep inspiration breath hold (DIBH) for locally advanced lung cancer. Twenty patients were enrolled in this prospective study. Two FDG PET/CT scans per patient were conducted few days apart and in two breathing conditions (FB and DIBH). This resulted in four scans per patient. Up to four FDG PET avid lesions per patient were contoured. The following FDG metrics were measured in all lesions and in all four scans: Standardized uptake value (SUV)peak , SUVmax , SUVmean , metabolic tumor volume (MTV) and total lesion glycolysis (TLG), based on an isocontur of 50% of SUVmax ...
2018: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29740971/target-position-reproducibility-in-left-breast-irradiation-with-deep-inspiration-breath-hold-using-multiple-optical-surface-control-points
#5
Aurora Fassi, Giovanni B Ivaldi, Paola Tabarelli de Fatis, Marco Liotta, Ilaria Meaglia, Patrizia Porcu, Lea Regolo, Marco Riboldi, Guido Baroni
The aim of this study was to investigate the use of 3D optical localization of multiple surface control points for deep inspiration breath-hold (DIBH) guidance in left-breast radiotherapy treatments. Ten left-breast cancer patients underwent whole-breast DIBH radiotherapy controlled by the Real-time Position Management (RPM) system. The reproducibility of the tumor bed (i.e., target) was assessed by the position of implanted clips, acquired through in-room kV imaging. Six to eight passive fiducials were positioned on the patients' thoraco-abdominal surface and localized intrafractionally by means of an infrared 3D optical tracking system...
May 8, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29699893/resource-requirements-and-reduction-in-cardiac-mortality-from-deep-inspiration-breath-hold-dibh-radiation-therapy-for-left-sided-breast-cancer-patients-a-prospective-service-development-analysis
#6
Sanjoy Chatterjee, Santam Chakraborty, Arunsingh Moses, Chandran Nallathambi, Anurupa Mahata, Samar Mandal, Rimpa Basu Achari, Indranil Mallick, Raj Kumar Shrimali, Tapesh Bhattacharyya, Sanjit Agrawal, Joydeep Ghosh, Rosina Ahmed
INTRODUCTION: Use of deep inspiration breath hold (DIBH) radiation therapy may reduce long-term cardiac mortality. The resource and time commitments associated with DIBH are impediments to its widespread adoption. We report the dosimetric benefits, workforce requirements, and potential reduction in cardiac mortality when DIBH is used for left-sided breast cancers. METHODS AND MATERIALS: Data regarding the time consumed for planning and treating 50 patients with left-sided breast cancer with DIBH and 20 patients treated with free breathing (FB) radiation therapy were compiled prospectively for all personnel (regarding person-hours [PH])...
March 21, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29670854/deep-inspiration-breath-hold-techniques-and-advantages-for-cardiac-sparing-during-breast-cancer-irradiation
#7
REVIEW
Carmen Bergom, Adam Currey, Nina Desai, An Tai, Jonathan B Strauss
Historically, heart dose from left-sided breast radiotherapy has been associated with a risk of cardiac injury. Data suggests that there is not a threshold for the deleterious effects from radiation on the heart. Over the past several years, advances in radiation delivery techniques have reduced cardiac morbidity due to treatment. Deep inspiration breath hold (DIBH) is a technique that takes advantage of a more favorable position of the heart during inspiration to minimize heart doses over a course of radiation therapy...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29605120/assessment-of-deep-inspiration-breath-hold-dibh-amplitude-and-reduction-in-cardiac-dose-in-left-breast-cancer-patients
#8
D Ledsom, A J Reilly, H Probst
INTRODUCTION: The primary aim of this study was to examine the impact of deep inspiration breath-hold (DIBH) amplitude on subsequent mean heart dose and V30 during radiotherapy. The secondary aim was to investigate if patient age influenced DIBH amplitude. METHOD: A retrospective study of 30 patients with left-sided breast cancer was completed. Patients were randomly selected from the total number of patients dual scanned in free breathing (FB) and DIBH over a 2-year period...
May 2018: Radiography
https://www.readbyqxmd.com/read/29587881/teddi-radiotherapy-delivery-in-deep-inspiration-for-pediatric-patients-a-nopho-feasibility-study
#9
Anni Young Lundgaard, Lisa Lyngsie Hjalgrim, Laura Ann Rechner, Mirjana Josipovic, Morten Joergensen, Marianne Camille Aznar, Anne Kill Berthelsen, Lise Borgwardt, Christoffer Johansen, Annika Loft, Akmal Safwat, Leila Vaalavirta, Lena Specht, Maja Vestmoe Maraldo
BACKGROUND: Radiotherapy (RT) delivered in deep inspiration breath-hold (DIBH) is a simple technique, in which changes in patient anatomy can significantly reduce the irradiation of the organs at risk (OARs) surrounding the treatment target. DIBH is routinely used in the treatment of some adult patients to diminish the risk of late effects; however, no formalized studies have addressed the potential benefit of DIBH in children. METHODS/DESIGN: TEDDI is a multicenter, non-randomized, feasibility study...
March 27, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29520213/voluntary-deep-inspiration-breath-hold-reduces-the-heart-dose-without-compromising-the-target-volume-coverage-during-radiotherapy-for-left-sided-breast-cancer
#10
Noora Al-Hammadi, Palmira Caparrotti, Carole Naim, Jillian Hayes, Katherine Rebecca Benson, Ana Vasic, Hissa Al-Abdulla, Rabih Hammoud, Saju Divakar, Primoz Petric
Background: During radiotherapy of left-sided breast cancer, parts of the heart are irradiated, which may lead to late toxicity. We report on the experience of single institution with cardiac-sparing radiotherapy using voluntary deep inspiration breath hold (V-DIBH) and compare its dosimetric outcome with free breathing (FB) technique. Patients and methods: Left-sided breast cancer patients, treated at our department with postoperative radiotherapy of breast/chest wall +/- regional lymph nodes between May 2015 and January 2017, were considered for inclusion...
March 2018: Radiology and Oncology
https://www.readbyqxmd.com/read/29506325/the-impact-of-continuous-positive-airway-pressure-on-radiation-dose-to-heart-and-lung-during-left-sided-postmastectomy-radiotherapy-when-deep-inspiration-breath-hold-technique-is-not-applicable-a-case-report
#11
Whoon Jong Kil, Tabitha Pham, Sabbir Hossain, Juan Casaigne, Kellie Jones, Mohammad Khalil
Deep inspiration breathing hold (DIBH) compared to free-breathing (FB) during radiotherapy (RT) has significantly decreased radiation dose to heart and has been one of the techniques adopted for patients with breast cancer. However, patients who are unable to make suitable deep inspiration breath may not be eligible for DIBH, yet still need to spare the heart and lung during breast cancer RT (left-sided RT in particular). Continuous positive airway pressure (CPAP) is a positive airway pressure ventilator, which keeps the airways continuously open and subsequently inflates the thorax resembling thoracic changes from DIBH...
March 2018: Radiation Oncology Journal
https://www.readbyqxmd.com/read/29472076/robustness-of-vmat-and-3dcrt-plans-toward-setup-errors-in-radiation-therapy-of-locally-advanced-left-sided-breast-cancer-with-dibh
#12
Christer Andre Jensen, Ana María Acosta Roa, Marie Johansen, Jo-Åsmund Lund, Jomar Frengen
PURPOSE: The aim of our study was to evaluate and compare the robustness of treatment plans produced using the volumetric modulated arc-therapy (VMAT) and the standard three-dimensional conformal radiotherapy (3DCRT) techniques by estimating perturbed doses induced by localization offsets for deep inspiration breath-hold (DIBH) in locally advanced breast cancer radiation therapy. METHODS: Twenty patients with left breast carcinoma requiring radiation therapy were analysed in this planning study...
January 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29452867/deep-inspiration-breath-hold-level-variability-and-deformation-in-locoregional-breast-irradiation
#13
Leigh Conroy, Sarah Quirk, Elizabeth Watt, Gillian Ecclestone, Jessica L Conway, Ivo A Olivotto, Tien Phan, Wendy L Smith
PURPOSE: The purpose of this study was to evaluate the dosimetric effect of breath hold level variability and deformation on breast, chest wall, internal mammary chain (IMC) nodes, and heart. METHODS AND MATERIALS: Left-sided post-lumpectomy (n = 12) and postmastectomy (n = 3) patients underwent deep inspiration breath hold (DIBH) and exhale breath hold (EBH) computed tomography (CT) scans. Forward-planned locoregional breast plans were created on the DIBH scan...
May 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29436168/feasibility-study-of-individualized-optimal-positioning-selection-for-left-sided-whole-breast-radiotherapy-dibh-or-prone
#14
Hui Lin, Tianyu Liu, Chengyu Shi, Saskia Petillion, Isabelle Kindts, Caroline Weltens, Tom Depuydt, Yulin Song, Ziad Saleh, Xie George Xu, Xiaoli Tang
The deep inspiration breath hold (DIBH) and prone (P) position are two common heart-sparing techniques for external-beam radiation treatment of left-sided breast cancer patients. Clinicians select the position that is deemed to be better for tissue sparing based on their experience. This approach, however, is not always optimum and consistent. In response to this, we develop a quantitative tool that predicts the optimal positioning for the sake of organs at risk (OAR) sparing. Sixteen left-sided breast cancer patients were considered in the study, each received CT scans in the supine free breathing, supine DIBH, and prone positions...
March 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29139223/dosimetric-effects-of-intrafractional-isocenter-variation-during-deep-inspiration-breath-hold-for-breast-cancer-patients-using-surface-guided-radiotherapy
#15
Malin Kügele, Anneli Edvardsson, Lovisa Berg, Sara Alkner, Carina Andersson Ljus, Sofie Ceberg
The aim of this study was to investigate potential dose reductions to the heart, left anterior descending coronary artery (LAD), and ipsilateral lung for left-sided breast cancer using visually guided deep inspiration breath-hold (DIBH) with the optical surface scanning system Catalyst™, and how these potential dosimetric benefits are affected by intrafractional motion in between breath holds. For both DIBH and free breathing (FB), treatment plans were created for 20 tangential and 20 locoregional left-sided breast cancer patients...
January 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29125857/phantom-based-evaluation-of-dose-exposure-of-ultrafast-combined-kv-mv-cbct-towards-clinical-implementation-for-igrt-of-lung-cancer
#16
Anna Arns, Manuel Blessing, Jens Fleckenstein, Dzmitry Stsepankou, Judit Boda-Heggemann, Juergen Hesser, Frank Lohr, Frederik Wenz, Hansjoerg Wertz
PURPOSE: Combined ultrafast 90°+90° kV-MV-CBCT within single breath-hold of 15s has high clinical potential for accelerating imaging for lung cancer patients treated with deep inspiration breath-hold (DIBH). For clinical feasibility of kV-MV-CBCT, dose exposure has to be small compared to prescribed dose. In this study, kV-MV dose output is evaluated and compared to clinically-established kV-CBCT. METHODS: Accurate dose calibration was performed for kV and MV energy; beam quality was determined...
2017: PloS One
https://www.readbyqxmd.com/read/29066123/deep-inspiration-breath-hold-radiation-therapy-in-breast-cancer-a-word-of-caution-on-the-dose-to-the-axillary-lymph-node-levels
#17
Kai Joachim Borm, Markus Oechsner, Stephanie E Combs, Marciana-Nona Duma
PURPOSE: To assess the differences in unintended regional nodal irradiation between free breathing (FB) and deep-inspiration breath-hold (DIBH) during tangential field irradiation. METHODS AND MATERIALS: We randomly chose 32 patients from our database who underwent both DIBH and FB treatment planning. Contouring of the axillary lymph node levels (LI, LII, and LIII) was performed retrospectively according to the Radiation Therapy Oncology Group contouring atlas...
January 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29040022/added-value-of-a-single-fast-20-second-deep-inspiration-breath-hold-acquisition-in-fdg-pet-ct-in-the-assessment-of-lung-nodules
#18
Nicolas Balamoutoff, Benjamin Serrano, Florent Hugonnet, Nicolas Garnier, Benoît Paulmier, Marc Faraggi
Purpose To compare the accuracy of a single 20-second deep-inspiration breath hold (DIBH) in fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) to that with conventional free-breathing (FB) whole-body PET/CT for the assessment, characterization, and quantification of lung lesions in terms of the blurring effect of respiratory motion. Materials and Methods Institutional review board approval was obtained, and the requirement to obtain informed consent was waived. A preclinical study was performed in a test population of 19 patients to evaluate the feasibility and consistency of DIBH techniques compared with phase-based respiratory gating (PBRG)...
January 2018: Radiology
https://www.readbyqxmd.com/read/28974856/cardiac-dose-reduction-with-deep-inspiratory-breath-hold-technique-of-radiotherapy-for-left-sided-breast-cancer
#19
Lalitha Kameshwari Sripathi, Parveen Ahlawat, David K Simson, Chira Ranjan Khadanga, Lakshmipathi Kamarsu, Shital Kumar Surana, Kavi Arasu, Harpreet Singh
INTRODUCTION: Different techniques of radiation therapy have been studied to reduce the cardiac dose in left breast cancer. AIM: In this prospective dosimetric study, the doses to heart as well as other organs at risk (OAR) were compared between free-breathing (FB) and deep inspiratory breath hold (DIBH) techniques in intensity modulated radiotherapy (IMRT) and opposed-tangent three-dimensional radiotherapy (3DCRT) plans. MATERIALS AND METHODS: Fifteen patients with left-sided breast cancer underwent computed tomography simulation and images were obtained in both FB and DIBH...
July 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/28916844/left-sided-breast-cancer-and-risks-of-secondary-lung-cancer-and-ischemic-heart-disease-effects-of-modern-radiotherapy-techniques
#20
Stefanie Corradini, Hendrik Ballhausen, Helmut Weingandt, Philipp Freislederer, Stephan Schönecker, Maximilian Niyazi, Cristoforo Simonetto, Markus Eidemüller, Ute Ganswindt, Claus Belka
PURPOSE: Modern breast cancer radiotherapy techniques, such as respiratory-gated radiotherapy in deep-inspiration breath-hold (DIBH) or volumetric-modulated arc radiotherapy (VMAT) have been shown to reduce the high dose exposure of the heart in left-sided breast cancer. The aim of the present study was to comparatively estimate the excess relative and absolute risks of radiation-induced secondary lung cancer and ischemic heart disease for different modern radiotherapy techniques. METHODS: Four different treatment plans were generated for ten computed tomography data sets of patients with left-sided breast cancer, using either three-dimensional conformal radiotherapy (3D-CRT) or VMAT, in free-breathing (FB) or DIBH...
March 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
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