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Vmat "bilateral breast"

Alba Fiorentino, Umberto Tebano, Ruggero Ruggieri, Francesco Ricchetti, Filippo Alongi
AIM: For simultaneous bilateral breast cancer (SBBC) treatment, conventional radiotherapy (RT) has a number of critical shortcomings. Thus, the usefulness of volumetric arc therapy (VMAT) for SBBC is undeniable. CASE REPORT: A 34-year-old woman with SBBC received neoadjuvant chemotherapy followed by breast-conserving surgery and bilateral lymph node dissection. Given the conservative surgery and the nodal involvement after neoadjuvant chemotherapy, bilateral adjuvant RT to the breasts and regional nodes with doses of 50 Gy in 25 fractions and a simultaneous integrated boost (SIB) of 60 Gy to the surgical bed was proposed...
September 27, 2016: Tumori
Antonella Fogliata, Giorgia Nicolini, Celine Bourgier, Alessandro Clivio, Fiorenza De Rose, Pascal Fenoglietto, Francesca Lobefalo, Pietro Mancosu, Stefano Tomatis, Eugenio Vanetti, Marta Scorsetti, Luca Cozzi
PURPOSE: To evaluate the performance of a model-based optimisation process for volumetric modulated arc therapy, VMAT, applied to whole breast irradiation. METHODS AND MATERIALS: A set of 150 VMAT dose plans with simultaneous integrated boost were selected to train a model for the prediction of dose-volume constraints. The dosimetric validation was done on different groups of patients from three institutes for single (50 cases) and bilateral breast (20 cases). RESULTS: Quantitative improvements were observed between the model-based and the reference plans, particularly for heart dose...
2015: PloS One
Jan Seppälä, Janne Heikkilä, Kimmo Myllyoja, Kristiina Koskela
PURPOSE: The treatment planning of bilateral breast irradiation (BBI) is a challenging task. The overlapping of tangential fields is usually unavoidable without compromising the target coverage. The purpose of this study was to investigate the technical feasibility and benefits of a single isocentre volumetric modulated arc therapy (VMAT) in BBI. METHODS AND MATERIALS: Two women with bilateral breast cancer were included in this case study. The first patient (Pat#1) underwent a bilateral breast-conserving surgery and sentinel lymph node biopsy...
September 2015: Reports of Practical Oncology and Radiotherapy
Marta Scorsetti, Filippo Alongi, Antonella Fogliata, Sara Pentimalli, Pierina Navarria, Francesca Lobefalo, Carlos Garcia-Etienne, Alessandro Clivio, Luca Cozzi, Pietro Mancosu, Giorgia Nicolini, Eugenio Vanetti, Marco Eboli, Carlo Rossetti, Arianna Rubino, Andrea Sagona, Stefano Arcangeli, Wolfgang Gatzemeier, Giovanna Masci, Rosalba Torrisi, Alberto Testori, Marco Alloisio, Armando Santoro, Corrado Tinterri
BACKGROUND: To report results in terms of feasibility and early toxicity of hypofractionated simultaneous integrated boost (SIB) approach with Volumetric Modulated Arc Therapy (VMAT) as adjuvant treatment after breast-conserving surgery. METHODS: Between September 2010 and May 2011, 50 consecutive patients presenting early-stage breast cancer were submitted to adjuvant radiotherapy with SIB-VMAT approach using RapidArc in our Institution (Istituto Clinico Humanitas ICH)...
2012: Radiation Oncology
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