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complicated urinary infection

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https://www.readbyqxmd.com/read/29913473/meropenem-vaborbactam-vabomere-for-complicated-urinary-tract-infection
#1
(no author information available yet)
No abstract text is available yet for this article.
June 18, 2018: Medical Letter on Drugs and Therapeutics
https://www.readbyqxmd.com/read/29912399/clinical-activity-of-ceftazidime-avibactam-against-mdr-enterobacteriaceae-and-pseudomonas-aeruginosa-pooled-data-from-the-ceftazidime-avibactam-phase-iii-clinical-trial-programme
#2
Gregory G Stone, Paul Newell, Leanne B Gasink, Helen Broadhurst, Angela Wardman, Katrina Yates, Zhangjing Chen, Jie Song, Joseph W Chow
Objectives: This analysis evaluated the clinical activity of ceftazidime/avibactam against MDR Enterobacteriaceae and Pseudomonas aeruginosa isolates pooled from the adult Phase III clinical trials in patients with complicated intra-abdominal infection (cIAI), complicated urinary tract infection (cUTI) or nosocomial pneumonia (NP) including ventilator-associated pneumonia (VAP). Methods: Baseline isolates from five Phase III randomized controlled trials of ceftazidime/avibactam versus predominantly carbapenem comparators in patients with cIAI (RECLAIM 1 and 2; NCT01499290 and RECLAIM 3; NCT01726023), cUTI (RECAPTURE 1 and 2; NCT01595438 and NCT01599806), NP including VAP (REPROVE; NCT01808092) and cIAI or cUTI caused by ceftazidime-non-susceptible Gram-negative pathogens (REPRISE; NCT01644643) were tested for MDR status and susceptibility to ceftazidime/avibactam and carbapenem-based comparators using CLSI broth microdilution methodology...
June 14, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29911455/delafloxacin-a-novel-fluoroquinolone-with-activity-against-methicillin-resistant-staphylococcus-aureus-mrsa-and-pseudomonas-aeruginosa
#3
Eric R Ocheretyaner, Tae Eun Park
The resistance to current antimicrobial agents, including fluoroquinolones, has continued to grow among various pathogens indicating a need for new antimicrobials to combat multi-drug resistant (MDR) organisms. In June 2017, delafloxacin received approval by the United States Food and Drug Administration for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) in adults caused by designated susceptible bacteria. Areas covered: This review describes the pharmacology, pharmacodynamics, pharmacokinetics, product information, efficacy, and safety of delafloxacin...
June 18, 2018: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29908216/complications-of-delivery-among-mothers-with-spina-bifida
#4
Courtney L Shepard, Phyllis L Yan, Stephanie J Kielb, Daniela A Wittmann, Elisabeth H Quint, Kate H Kraft, John M Hollingsworth
OBJECTIVE: To determine rates and types of peripartum morbidity among delivering women with spina bifida (SB) compared to those without SB. The rates of pregnancy and delivery among women with SB have been significantly increasing. Current knowledge of peripartum outcomes for these women is limited. METHODS: Using 2004-2013 National Inpatient Sample data, we identified all hospitalizations for delivery, distinguishing between women with and without SB. Using a code-based algorithm, we determined whether a complication occurred during the hospitalization...
June 13, 2018: Urology
https://www.readbyqxmd.com/read/29907162/schistosomiasis-in-immigrants-refugees-and-travellers-in-an-italian-referral-centre-for-tropical-diseases
#5
Valentina Marchese, Anna Beltrame, Andrea Angheben, Geraldo Badona Monteiro, Giovanni Giorli, Francesca Perandin, Dora Buonfrate, Zeno Bisoffi
BACKGROUND: Schistosomiasis is one of the most important neglected tropical diseases. If unrecognised and untreated, the chronic infection can lead to irreversible complications. METHODS: Retrospective observational study aimed at describing clinical history, laboratory findings and imaging presentation of imported schistosomiasis diagnosed at the Centre for Tropical Diseases, Sacro Cuore Don Calabria Hospital of Negrar, Verona, Italy from 2010 to 2014. The aim of our study was to assess differences in demographic characteristics, clinical presentation, laboratory data and ultrasound findings between immigrants/visiting friends and relatives (VFR) from endemic countries (endemic group) and expatriates/travellers (non-endemic group)...
June 16, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29906435/the-association-of-previous-prostate-biopsy-related-complications-and-the-type-of-complication-with-patient-compliance-with-re-biopsy-scheme
#6
Logan S Schwarzman, Michael R Abern, Daniel F Garvey, Gerald L Andriole, Stephen J Freedland, Daniel M Moreira
INTRODUCTION: Prostate biopsy complications have important consequences that may affect patient compliance with re-biopsy schemes; however, this has not been studied in earnest. Thus, we evaluated whether previous prostate biopsy-related complications and the type of complication were associated with repeat prostate biopsy compliance in a clinical trial with study-mandated systematic biopsies. MATERIALS AND METHODS: Retrospective analysis of 4,939 men ages 50-75 who underwent a 2-year prostate biopsy and were recommended to undergo the 4-year prostate re-biopsy in the Reduction by Dutasteride of prostate cancer Events (REDUCE) study...
June 12, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29905016/examining-the-july-effect-on-patients-undergoing-pituitary-surgery
#7
Bassel Bashjawish, Shreya Patel, Suat Kılıç, Wayne D Hsueh, James K Liu, Soly Baredes, Jean Anderson Eloy
BACKGROUND: Our aim in this study was to assess the impact of the turnover of residents in July on patients undergoing pituitary surgery. METHODS: This work was a retrospective cohort study of cases from the National Inpatient Sample (NIS). Patients who underwent pituitary surgery from 2005 to 2012 were selected in the NIS. Patients undergoing surgery in July and in non-July months were compared to determine differences in demographics, comorbidities, and complications...
June 15, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29904419/value-of-procalcitonin-for-diagnosing-perioperative-pneumonia-urinary-infections-and-superficial-surgical-site-infections-in-patients-undergoing-primary-hip-and-knee-arthroplasty
#8
Lixuan Zhang, Daozhang Cai, Hanming Guo
Serum procalcitonin (PCT) levels may be helpful for the diagnosis of infections during the perioperative period of arthroplasty. However, there is much debate in the literature regarding the appropriate cut-off value for different types of surgery and local bacterial infection. The present study aimed to evaluate serum PCT levels in patients undergoing arthroplasty and to determine the cut-off value that may represent perioperative pneumonia, urinary infections and superficial surgical site infections. The present retrospective study included a total of 500 patients treated between July 2014 and August 2015...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29901799/the-use-of-a-silver-nylon-dressing-during-evacuation-of-military-burn-casualties
#9
Amit Aurora, Alexander Beasy, Julie A Rizzo, Kevin K Chung
The military has used silver-nylon dressings as a topical antimicrobial on combat-related burns for the past 15 years. However, their clinical efficacy and associated risks have not been evaluated. Herein, the authors document our experience with the use of a specific silver-nylon dressing (Silverlon®) during global evacuation of casualties from combat zones to the United States sArmy Institute of Surgical Research Burn Center. A 10-year retrospective analysis was performed. Variables included patient demographics, total body surface area, length of stay, Injury Severity Score, incidence of urinary tract and burn infections, pneumonia, patient status at the time of discharge, and a composite endpoint...
June 13, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29898664/an-unusual-diverticulum-adjacent-to-two-large-colonic-polyps-a-case-report
#10
John Schembri, Jonathan Bury, Lesley Hunt, Stuart Riley
BACKGROUND: Adenocarcinomas can arise in a variety of circumstances in which intestinal segments have been used for urinary diversions. Whereas ureterosigmoidostomy is the oldest and simplest form of continent urinary diversion it also seems to be the most dangerous in this regard. Herein we present a case of colonic neoplasia complicating a non-functioning ureterosigmoidostomy after 55 years; the longest latent period documented to date. CASE PRESENTATION: A 56-year-old lady born with congenital bladder exystrophy and who had a functional ileal conduit presented to us with a 6 month history of change in bowel habit and rectal bleeding...
June 14, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29894326/stress-urinary-incontinence-surgery-in-washington-state-before-and-after-introduction-of-the-mesh-midurethral-sling
#11
Lauren E Stewart, Michelle A Eston, Rebecca G Symons, Michael F Fialkow, Anna C Kirby
OBJECTIVES: Mesh midurethral slings (MUSs) are safe, effective treatments for female stress urinary incontinence (SUI), but many companies have ceased production because of controversies surrounding transvaginal mesh. To determine if introduction of MUS has increased the complication rate associated with SUI surgery, we compared women undergoing SUI surgery in the MUS era to those who had surgery prior its introduction. METHODS: This was a retrospective cohort study of a statewide hospital discharge database...
June 12, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29893802/efficacy-of-ceftazidime-avibactam-salvage-therapy-in-patients-with-infections-caused-by-kpc-producing-klebsiella-pneumoniae
#12
Mario Tumbarello, Enrico Maria Trecarichi, Alberto Corona, Francesco Giuseppe De Rosa, Matteo Bassetti, Cristina Mussini, Francesco Menichetti, Claudio Viscoli, Caterina Campoli, Mario Venditti, Andrea De Gasperi, Alessandra Mularoni, Carlo Tascini, Giustino Parruti, Carlo Pallotto, Simona Sica, Ercole Concia, Rosario Cultrera, Gennaro De Pascale, Alessandro Capone, Spinello Antinori, Silvia Corcione, Elda Righi, Angela Raffaella Losito, Margherita Digaetano, Francesco Amadori, Daniele Roberto Giacobbe, Giancarlo Ceccarelli, Ernestina Mazza, Francesca Raffaelli, Teresa Spanu, Roberto Cauda, Pierluigi Viale
Background: Ceftazidime-avibactam (CAZ-AVI) has been approved in Europe for the treatment of complicated intra-abdominal and urinary-tract infections, as well as hospital-acquired pneumonia, and for Gram-negative infections with limited treatment options. CAZ-AVI displays in vitro activity against KPC-enzyme producers, but clinical-trial data on its efficacy in this setting are lacking. Methods: We retrospectively reviewed 138 cases of infections caused by Klebsiella pneumoniae carbapenemase-producing (KPC-Kp) in adults who received CAZ-AVI in compassionate-use programs in Italy...
June 9, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29893777/particulate-wear-debris-osteolysis-acute-urinary-retention-and-delirium-as-late-complications-of-hip-arthroplasty
#13
Carmen Benitez, Javier Pérez-Jara, Luis Garcia-Paino, Teresa Montenegro, Encarnacion Martin, Arturo Vilches-Moraga
Intrapelvic mass formation as a result of particulate wear debris induced osteolysis is a recognised late complication of cementless total hip arthroplasty. Clinical presentation typically involves hip and/or leg pain resulting in functional impairment, and obstructive urinary symptoms developing 3-20 years after surgery. An acute confusional state has never been described in this scenario. We report the case of an 86-year-old gentleman with a diagnosis of dementia brought to our emergency department with an acute confusional state...
June 8, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29886920/complications-results-and-risk-factors-of-spinal-fusion-in-patients-with-myelomeningocele
#14
Bridget Ollesch, Christopher Brazell, Patrick M Carry, Gaia Georgopoulos
STUDY DESIGN: Retrospective prognostic study. OBJECTIVE: The purpose of this study assess was to assess the results of spinal fusion and identify factors associated with the development of post-spinal fusion infections in patients with myelomeningocele. BACKGROUND: Surgical correction of neuromuscular scoliosis secondary to myelomeningocele is known to be associated with a high complication rate. METHODS: A retrospective cohort study design was used to collect data on patients with myelomeningocele who underwent spinal fusion between the years of 1997-2013...
July 2018: Spine Deformity
https://www.readbyqxmd.com/read/29886114/toxic-epidermal-necrolysis-data-from-the-celeste-multinational-registry-part-i-epidemiology-and-general-microbiological-characteristics
#15
B Lipový, J Holoubek, M Hanslianová, M Cvanová, L Klein, I Grossová, R Zajíček, P Bukovčan, J Koller, M Baran, P Lengyel, L Eimer, M Jandová, M Košťál, P Brychta
INTRODUCTION: Toxic epidermal necrolysis (TEN) is a rare, life-threatening autoimmune disease predominantly manifested in the skin and mucous membranes. Today, infectious complications have the dominant share in mortality of TEN patients. Due to the nature of the therapy and administration of immunosuppressive medications, a wide range of potentially pathogenic microorganisms, which cause infectious complications in different compartments in these patients, is not surprising. MATERIAL AND METHODOLOGY: This is a multicentric study, which included all patients with TEN hospitalized between 2000-2015 in specialized centres in the Czech Republic and Slovakia...
June 6, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29881186/timing-of-complications-following-posterior-cervical-fusion
#16
J Mason DePasse, Wesley Durand, Adam E M Eltorai, Mark A Palumbo, Alan H Daniels
Study design: Retrospective cohort study. Objective: To characterize the timing of complications after posterior cervical fusion. Summary of background data: Understanding the expected timing of postoperative complications facilitates early diagnosis of potential adverse events and is important for optimizing postoperative care. Though studies have examined the incidence of complications after posterior cervical fusion, no study has characterized the timing of these complications...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29878700/nice-guidance-complicated-urinary-tract-infections-ceftolozane-tazobactam-%C3%A2-nice-2016-complicated-urinary-tract-infections-ceftolozane-tazobactam
#17
(no author information available yet)
No abstract text is available yet for this article.
June 2018: BJU International
https://www.readbyqxmd.com/read/29877001/clinical-significance-of-isoagglutinin-titer-with-the-current-desensitization-protocol-in-abo-incompatible-kidney-transplantation
#18
Chung Hee Baek, Hyosang Kim, Won Seok Yang, Duck Jong Han, Su-Kil Park
AIM: ABO-incompatible (ABOi) kidney transplantation (KT) has become a routine procedure with graft survival rates comparable to those of ABO-compatible KT. However, the clinical significance of the isoagglutinin titer in ABOi KT remains uncertain. Therefore, in this study, we analyzed the clinical outcomes of ABOi KT according to the baseline and postoperative isoagglutinin titer. METHODS: All patients who received ABOi KT between 2009 and 2013 were reviewed and followed up until December 2016...
June 7, 2018: Nephrology
https://www.readbyqxmd.com/read/29872326/mecillinam-for-the-treatment-of-acute-pyelonephritis-and-bacteremia-caused-by-enterobacteriaceae-a-literature-review
#19
REVIEW
Filip Jansåker, Niels Frimodt-Møller, Thomas L Benfield, Jenny Dahl Knudsen
Purpose: The pharmacokinetic properties of mecillinam (MEC) for urinary tract infections are excellent, and the resistance rate in Enterobacteriaceae is low compared to other recommended antibiotics. The oral prodrug pivmecillinam (P-MEC) has been used successfully as first choice for cystitis in the Nordic countries for many years. Norwegian and Danish guidelines also recommend P-MEC for acute uncomplicated pyelonephritis (AUP) and intravenous (IV) MEC for suspected urosepsis (only in Denmark)...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29871832/the-impact-of-chronic-obstructive-pulmonary-disease-on-postoperative-outcomes-in-patients-undergoing-revision-total-knee-arthroplasty
#20
Alex Gu, Chapman Wei, Camilla M Maybee, Shane A Sobrio, Matthew P Abdel, Peter K Sculco
BACKGROUND: Total knee arthroplasty (TKA) utilization is increasing in older Americans. The incidence of chronic obstructive pulmonary disease (COPD) has been steadily rising over the past few decades. In particular, COPD is being increasingly more common in patients undergoing revision TKA. The aim of this study is to identify the impact of COPD on postoperative complications for patients undergoing revision TKA. METHODS: A retrospective cohort study was conducted using data collected through the American College of Surgeons National Quality Improvement Program Database...
May 14, 2018: Journal of Arthroplasty
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