keyword
https://read.qxmd.com/read/38644636/associations-between-carotid-plaque-shape-biomechanical-parameters-and-ischemic-stroke-in-mild-carotid-stenosis-with-a-single-plaque
#21
JOURNAL ARTICLE
Man Zhao, Luni Zhang, Jing Chen, Shiyao Gu, Rong Wu, Caixia Jia
PURPOSE: This cross-sectional cohort-comparison observational study investigated the value of high-frame-rate vector flow (V Flow) imaging for evaluating differences in carotid plaque shape and biomechanical parameters in patients with mild stenosis according to a recent history of ipsilateral ischemic stroke. METHODS: The present study included 352 patients from February 2023 to October 2023, who were categorized as symptomatic or asymptomatic based on a history of recent ischemic stroke and ipsilateral ischemic lesions detected on head computed tomography or magnetic resonance imaging...
April 2, 2024: Ultrasonography
https://read.qxmd.com/read/38644498/two-cases-of-diquat-poisoning-in-adolescent-children
#22
JOURNAL ARTICLE
Mengtao Duan, Baowang Yang, Xiaohang Cheng, Fuhui Shen, Xia Lu, Fan Wang
Diquat (DQ) is among the most widely used herbicides, and its intake can cause severe systemic toxicity that manifests rapidly. The resultant symptoms can cause the dysfunction of a range of tissues and organs,. As there is no specific antidote for diquat poisoning and the efficacy of extant treatments is suboptimal, physicians must acquire a more comprehensive understanding of the most effective approaches to managing affected patients. Relative few studies have been published to date focused on diquat poisoning in pediatric patients...
April 22, 2024: Italian Journal of Pediatrics
https://read.qxmd.com/read/38643642/evidence-of-deviations-between-experimental-and-empirical-mixing-lengths-multi-discharge-field-tests-in-an-arid-river-system
#23
JOURNAL ARTICLE
Aashish Khandelwal, Tzion Castillo, Ricardo González-Pinzón
Despite advances in wastewater treatment plant (WWTP) efficiencies, multiple contaminants of concern, such as microplastics, pharmaceuticals, and per- and poly-fluoroalkyl substances (PFAS) remain largely untreated near discharge points and can be highly concentrated before they are fully mixed within the receiving river. Environmental agencies enforce mixing zone permits for the temporary exceedance of water quality parameters beyond targeted control levels under the assumption that contaminants are well-mixed and diluted downstream of mixing lengths, which are typically quantified using empirical equations derived from one-dimensional transport models...
April 17, 2024: Water Research
https://read.qxmd.com/read/38643613/electrode-positioning-errors-reduce-current-dose-for-focal-tdcs-set-ups-evidence-from-individualized-electric-field-mapping
#24
JOURNAL ARTICLE
Filip Niemann, Steffen Riemann, Ann-Kathrin Hubert, Daria Antonenko, Axel Thielscher, Andrew K Martin, Nina Unger, Agnes Flöel, Marcus Meinzer
OBJECTIVE: Electrode positioning errors contribute to variability of transcranial direct current stimulation (tDCS) effects. We investigated the impact of electrode positioning errors on current flow for tDCS set-ups with different focality. METHODS: Deviations from planned electrode positions were determined using data acquired in an experimental study (N = 240 datasets) that administered conventional and focal tDCS during magnetic resonance imaging (MRI)...
April 10, 2024: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/38643350/the-role-of-optical-coherence-tomography-angiography-in-glaucoma
#25
REVIEW
Maximilian Braun, Chhavi Saini, Jessica A Sun, Lucy Q Shen
Glaucoma is the leading cause of irreversible vision loss and comprises a group of chronic optic neuropathies characterized by progressive retinal ganglion cell (RGC) loss. Various etiologies, including impaired blood supply to the optic nerve, have been implicated for glaucoma pathogenesis. Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality for visualizing the ophthalmic microvasculature. Using blood flow as an intrinsic contrast agent, it distinguishes blood vessels from the surrounding tissue...
April 20, 2024: Seminars in Ophthalmology
https://read.qxmd.com/read/38642854/biofilm-growth-on-orthopaedic-cerclage-materials-non-metallic-polymers-are-less-resistant-to-methicillin-resistant-staphylococcus-aureus-bacterial-adhesion
#26
JOURNAL ARTICLE
Kyle H Cichos, Matthew C Christie, Brent A Ponce, Elie S Ghanem
INTRODUCTION: Data on bacterial adhesion to cerclage cables is sparse. We aimed to compare five cerclage products for methicillin-resistant Staphylococcus aureus (MRSA) adhesion to determine: Are non-metallic polymer cables more resistant to bacterial adhesion than common metallic wires and cables? MATERIALS AND METHODS: The following five cerclage products were compared: 1) monofilament stainless steel (SS) wires; 2) multifilament SS cables; 3) multifilament cobalt chrome (CoCr) cables; 4) multifilament Vitalium alloy (cobalt-chrome-molybdenum [Co-Cr-Mo]) cables; and 5) multifilament non-metallic polymer cables...
April 18, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38641263/impact-of-endothelial-shear-stress-on-coronary-atherosclerotic-plaque-progression-and-composition-a-meta-analysis-and-systematic-review
#27
JOURNAL ARTICLE
Alessandro Candreva, Antonia Luisa Buongiorno, Michael Adrian Matter, Maurizio Lodi Rizzini, Federico Giacobbe, Emanuele Ravetti, Giuseppe Giannino, Ludovica Carmagnola, Thomas Gilhofer, Diego Gallo, Claudio Chiastra, Barbara E Stähli, Mario Iannaccone, Umberto Morbiducci, Italo Porto, Gaetano Maria De Ferrari, Fabrizio D'Ascenzo
BACKGROUND AND AIMS: Intracoronary pressure gradients and translesional flow patterns have been correlated with coronary plaque progression and lesion destabilization. In this study, we aimed to determine the relationship between endothelial shear stress and plaque progression and to evaluate the effect of shear forces on coronary plaque features. METHODS: A systematic review was conducted in medical on-line databases. Selected were studies including human participants who underwent coronary anatomy assessment with computational fluid dynamics (CFD)-based wall shear stress (WSS) calculation at baseline with anatomical evaluation at follow-up...
April 17, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38641184/comparative-analysis-of-traction-forces-in-normal-and-glaucomatous-trabecular-meshwork-cells-within-a-3d-active-fluid-structure-interaction-culture-environment
#28
JOURNAL ARTICLE
Alireza Karimi, Mini Aga, Taaha Khan, Siddharth Daniel D'costa, Omkar Thaware, Elizabeth White, Mary J Kelley, Haiyan Gong, Ted S Acott
This study presents a 3D in vitro cell culture model, meticulously 3D printed to replicate the conventional aqueous outflow pathway anatomical structure, facilitating the study of trabecular meshwork (TM) cellular responses under glaucomatous conditions. Glaucoma affects TM cell functionality, leading to extracellular matrix (ECM) stiffening, enhanced cell-ECM adhesion, and obstructed aqueous humor outflow. Our model, reconstructed from polyacrylamide gel with elastic moduli of 1.5 and 21.7 kPa, is based on serial block-face scanning electron microscopy images of the outflow pathway...
April 17, 2024: Acta Biomaterialia
https://read.qxmd.com/read/38640922/the-gamma-variate-in-contrast-enhanced-imaging-a-unified-view-and-method-from-computed-to-electrical-impedance-tomography
#29
JOURNAL ARTICLE
Diogo Filipe Silva, Steffen Leonhardt
Modern medical imaging plays a vital role in clinical practice, enabling non-invasive visualization of anatomical structures. Dynamic contrast enhancement (DCE) imaging is a technique that uses contrast agents to visualize blood flow dynamics in a time-resolved manner. It can be applied to different modalities, such as computed tomography (CT) and electrical impedance tomography (EIT). This study aims to develop a common theoretical and practical hemodynamic extraction basis for DCE modelling across modalities, based on the gamma-variate function...
April 19, 2024: Physics in Medicine and Biology
https://read.qxmd.com/read/38640912/biomarker-based-human-and-animal-sperm-phenotyping-the-good-the-bad-and-the-ugly
#30
JOURNAL ARTICLE
Peter Sutovsky, Lauren E Hamilton, Michal Zigo, Mayra E Ortiz D'Avila Assumpção, Alexis Jones, Filip Tirpak, Yuksel Agca, Karl Kerns, Miriam Sutovsky
Conventional, brightfield-microscopic semen analysis provides important baseline information about sperm quality of an individual; however, it falls short of identifying subtle subcellular and molecular defects in cohorts of "bad", defective human and animal spermatozoa with seemingly normal phenotypes. To bridge this gap, it is desirable to increase the precision of andrological evaluation in humans and livestock animals by pursuing advanced biomarker-based imaging methods. This review, spiced up with occasional classic movie references but seriously scholastic at the same time, focuses mainly on the biomarkers of altered male germ cell proteostasis resulting in post-testicular carryovers of proteins associated with ubiquitin-proteasome system...
April 19, 2024: Biology of Reproduction
https://read.qxmd.com/read/38639621/evaluation-of-the-optimal-duration-of-thumb-cupping-therapy-for-frozen-shoulder-by-thermal-metabolic-imaging
#31
JOURNAL ARTICLE
Yan Liu, Yanli Xia, Hongwei Chen, Yuanyuan Zhu, Chaoju Zhang
OBJECTIVE: To evaluate the optimal duration of thumb cupping therapy for frozen shoulder (FS) by thermal metabolic imaging (TMI) and to provide clinical evidence. METHODS: From April 2022 to August 2023, 120 patients with FS who received thumb cupping therapy at our hospital were randomized into groups A, B, and C for 5, 10, and 15 minutes of cupping, respectively. The clinical efficacy, Visual Analogue Scale (VAS) score, and shoulder range of motion (ROM) of the three groups were compared, and the skin blood flow and the incidence of adverse reactions during treatment were analyzed...
April 18, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38638936/value-of-carotid-corrected-flow-time-or-changes-value-of-ftc-could-be-more-useful-in-predicting-fluid-responsiveness-in-patients-undergoing-robot-assisted-gynecologic-surgery-a-prospective-observational-study
#32
JOURNAL ARTICLE
Xixi Tang, Jingqiu Liang, Dongling Tan, Qi Chen, Chengfu Zhou, Tingjun Yang, Hongliang Liu
BACKGROUND: The aim of this study was to evaluate the ability of point-of-care Doppler ultrasound measurements of carotid corrected flow time and its changes induced by volume expansion to predict fluid responsiveness in patients undergoing robot-assisted gynecological surgery. METHODS: In this prospective study, carotid corrected flow time was measured using Doppler images of the common carotid artery before and after volume expansion. The stroke volume index at each time point was recorded using noninvasive cardiac output monitoring with MostCare...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38637920/changes-in-pancreas-volume-in-living-donor-liver-transplant-recipients
#33
JOURNAL ARTICLE
Cristal Brown, Callaghan Ray, Garrett Kuketz, John Virostko
BACKGROUND: Metabolic factors have a significant role in the morbidity and mortality associated with chronic liver disease. The pancreas has a central role in metabolism and metabolic risk factors but has been largely ignored in liver transplantation. Small pancreas volume has been demonstrated in pathologic conditions such as type 1 and 2 diabetes. METHODS: This study assessed abdominal imaging before and after liver transplantation to determine if liver transplantation induces changes in pancreas volume in living donor liver transplant recipients...
April 19, 2024: Transplantation
https://read.qxmd.com/read/38637680/measurement-of-mass-force-field-driving-water-refilling-of-cuttage
#34
JOURNAL ARTICLE
Mingwei Xu, Ke Li, Yanling Xue, Feixiang Wang, Zhixuan Liu, Tiqiao Xiao
Cuttage is a common plant cultivation method, and the key to its survival is the restoration of water refilling, which remains unclear up to now. We report 3D dynamic imaging of water refilling of cuttage without resorting to any contrast agent. Hydrodynamics of the refilled water flow over time reveals the existence of a unit mass force field with a gradient along the refilling direction, which means that cutting plants also have a gradient force field to drive the recovery of water refilling, as predicted by Cohesion-Tension theory in normal plants...
April 18, 2024: Scientific Reports
https://read.qxmd.com/read/38637675/imaging-the-top-of-the-earth-s-inner-core-a-present-day-flow-model
#35
JOURNAL ARTICLE
Hrvoje Tkalčić, Anatoly B Belonoshko, Jack B Muir, Maurizio Mattesini, Louis Moresi, Lauren Waszek
Despite considerable progress in seismology, mineral physics, geodynamics, paleomagnetism, and mathematical geophysics, Earth's inner core structure and evolution remain enigmatic. One of the most significant issues is its thermal history and the current thermal state. Several hypotheses involving a thermally-convecting inner core have been proposed: a simple, high-viscosity, translational mode, or a classical, lower-viscosity, plume-style convection. Here, we use state-of-the-art seismic imaging to probe the outermost shell of the inner core for its isotropic compressional speed and compare it with recently developed attenuation maps...
April 18, 2024: Scientific Reports
https://read.qxmd.com/read/38637025/brain-arteriovenous-malformation-in-vitro-model-for-transvenous-embolization-using-3d-printing-and-real-patient-data
#36
JOURNAL ARTICLE
Rodrigo Rivera, Alvaro Cespedes, Juan Pablo Cruz, Aymeric Rouchaud, Charbel Mounayer
BACKGROUND AND PURPOSE: Transvenous embolization has emerged as a novel technique for treating selected brain AVMs with high reported occlusion rates. However, it requires anatomic and technical skills to be successful and to ensure patient safety. Therefore, training and testing are essential for preparing clinicians to perform these procedures. Our aim was to develop and test a novel, patient-specific brain AVM in vitro model for transvenous embolization by using 3D printing technology...
April 18, 2024: AJNR. American Journal of Neuroradiology
https://read.qxmd.com/read/38636997/-study-on-liver-tissue-derived-extracellular-vesicles-regulating-the-osteogenic-differentiation-ability-of-mesenchymal-stem-cells-and-promoting-the-healing-of-jaw-bone-defects
#37
JOURNAL ARTICLE
C H Li, X Lei, C X Zheng, Y Jin, B D Sui, S Q Ying
Objective: To explore the biological process of liver tissue-derived extracellular vesicle (LT-EV) in promoting osteogenic differentiation of mesenchymal stem cells and healing of jaw defects to provide a feasible treatment method for the clinical treatment of jaw bone defects. Methods: Enzymatic hydrolysis and differential centrifugation were used to extract LT-EV, scanning electron microscopy, Western blotting, and nanoparticle tracking analyzers were used to identify and characterize LT-EV, and further to explore the biological functions of LT-EV through proteomics and Kyoto Encyclopedia of Genes and Genomes...
April 18, 2024: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://read.qxmd.com/read/38636674/application-of-3d-pcasl-combined-with-t-asl-and-mra-in-the-diagnosis-of-patients-with-isolated-vertigo-induced-by-posterior-circulation-ischemia
#38
JOURNAL ARTICLE
Xiaotong Xie, Lingjiang Mo, Peifan Liu, Chunxing Liu, Mouyuan Liu, Yongyan Deng, Peina Zhang, Jinglei Yuan, Ting Song, Liheng Ma
OBJECTIVES: Isolated vertigo induced by posterior circulation ischemia (PCIV) can further progress into posterior circulation infarction. This study aimed to explore the diagnostic values of three-dimensional pseudo-continuous arterial spin labeling (3D-PCASL) combined with territorial arterial spin labeling (t-ASL) and magnetic resonance angiography (MRA) in visualizing and evaluating PCIV, seeking improved diagnostic tools for clinical guidance. METHODS: 28 PCIVs (11 males, 17 females, aged from 55 to 83 years, mean age: 69...
April 16, 2024: Magnetic Resonance Imaging
https://read.qxmd.com/read/38636308/cavitation-suppression-and-transformation-of-turbulence-structure-in-the-cross-flow-around-a-circular-cylinder-surface-morphology-and-wettability-effects
#39
JOURNAL ARTICLE
Mikhail Yu Nichik, Boris B Ilyushin, Ebrahim Kadivar, Ould El Moctar, Konstantin S Pervunin
Passive methods of flow and cavitation control appear to offer some of the best prospects in the field of hydraulic engineering and marine applications. In this article, we aimed at an experimental examination of the effect of wall roughness/wettability on the occurrence of cavitation and turbulence structure in the cross flow around and in the wake of a circular cylinder in two characteristic regimes. For this, we used three test bodies with different surface morphologies: smooth (reference), micro-scale irregularities (rough) and regular large-scale (of the order of a millimeter) texture (finned)...
April 11, 2024: Ultrasonics Sonochemistry
https://read.qxmd.com/read/38636265/optimization-of-rf-coil-geometry-for-nmr-mri-applications-using-a-genetic-algorithm
#40
JOURNAL ARTICLE
Techit Tritrakarn, Masato Takahashi, Tetsuji Okamura
A simulation method that employs a genetic algorithm (GA) for optimizing radio frequency (RF) coil geometry is developed to maximize signal intensity in nuclear magnetic resonance (NMR)/magnetic resonance imaging (MRI) applications. NMR/MRI has a wide range of applications, including medical imaging, and chemical and biological analysis to investigate the structure, dynamics, and interactions of molecules. However, NMR suffers from inherently low signal intensity, which depends on factors related to RF coil geometry...
April 17, 2024: Journal of Magnetic Resonance
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