Alessandro Candreva, Antonia Luisa Buongiorno, Michael Adrian Matter, Maurizio Lodi Rizzini, Federico Giacobbe, Emanuele Ravetti, Giuseppe Giannino, Ludovica Carmagnola, Thomas Gilhofer, Diego Gallo, Claudio Chiastra, Barbara E Stähli, Mario Iannaccone, Umberto Morbiducci, Italo Porto, Gaetano Maria De Ferrari, Fabrizio D'Ascenzo
BACKGROUND AND AIMS: Intracoronary pressure gradients and translesional flow patterns have been correlated with coronary plaque progression and lesion destabilization. In this study, we aimed to determine the relationship between endothelial shear stress and plaque progression and to evaluate the effect of shear forces on coronary plaque features. METHODS: A systematic review was conducted in medical on-line databases. Selected were studies including human participants who underwent coronary anatomy assessment with computational fluid dynamics (CFD)-based wall shear stress (WSS) calculation at baseline with anatomical evaluation at follow-up...
April 17, 2024: International Journal of Cardiology