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https://www.readbyqxmd.com/read/29334079/first-heating-measurements-of-endovascular-stents-in-magnetic-particle-imaging
#1
Franz Wegner, Thomas Friedrich, Nikolaos Panagiotopoulos, Sarah Vaalma, Jan Peter Goltz, Florian M Vogt, Martin A Koch, Thorsten M Buzug, Joerg Barkhausen, Julian Haegele
Magnetic Particle Imaging (MPI) is a three-dimensional imaging method which visualizes the spatial distribution of Superparamagnetic Iron Oxide Nanoparticles (SPIOs) with oscillating and static magnetic fields. It is a quantitative method as the intensity of its signal is proportional to the concentration of the SPIOs. Due to its quantitativeness, high temporal resolution and kidney-safe tracers it is proposed to be a very promising noninvasive method for cardiovascular imaging. In this regard MPI in the presence of endovascular stents and assessment of stent patency with MPI has to be evaluated...
January 15, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29334078/high-prf-ultrafast-sliding-compound-doppler-imaging-fully-qualitative-and-quantitative-analysis-of-blood-flow
#2
Jinbum Kang, Won Seuk Jang, Yangmo Yoo
Ultrafast compound Doppler imaging based on plane-wave excitation (UCDI) can be used to evaluate cardiovascular diseases using high frame rates. In particular, it provides a fully quantifiable flow analysis over a large region of interest with high spatio-temporal resolution. However, the pulse-repetition frequency (PRF) in the UCDI method is limited for high-velocity flow imaging since it leverages between the number of plane-wave angles (<i>N</i>) and acquisition time. In this paper, we present high PRF ultrafast sliding compound Doppler imaging method (HUSDI) to improve quantitative flow analysis...
January 15, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29333914/hybrid-pet-mri-imaging-in-healthy-unsedated-newborn-infants-with-quantitative-rcbf-measurements-using-15o-water-pet
#3
Julie B Andersen, Ulrich Lindberg, Oline V Olesen, Didier Benoit, Claes N Ladefoged, Henrik Bw Larsson, Liselotte Højgaard, Gorm Greisen, Ian Law
In this study, a new hybrid PET/MRI method for quantitative regional cerebral blood flow (rCBF) measurements in healthy newborn infants was assessed and the low values of rCBF in white matter previously obtained by arterial spin labeling (ASL) were tested. Four healthy full-term newborn subjects were scanned in a PET/MRI scanner during natural sleep after median intravenous injection of 14 MBq 15O-water. Regional CBF was quantified using a one-tissue-compartment model employing an image-derived input function (IDIF) from the left ventricle...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29333467/a-simple-non-invasive-i-123-imp-autoradiography-method-developed-by-modifying-the-simple-non-invasive-i-123-imp-microsphere-method
#4
Asato Ofuji, Rieko Nagaoka, Kosuke Yamashita, Akihiro Takaki, Shigeki Ito
Objectives: We developed a simple non-invasive I-123-N-isopropyl-p-iodoamphetamine (123I-IMP) quantification method by analyzing chest RI-angiography and single photon emission computed tomography (SPECT) images based on the microsphere model (SIMS method). Theoretically, the SIMS method could be changed to the simple non-invasive ARG (SIARG) method by modifying the integrated washout ratio (WR) to one-point WR. If the regional cerebral blood flow (rCBF) values derived from the SIARG and ARG methods correlate well, the facilities employing the ARG method can easily switch to the SIARG method...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29332606/tricuspid-flow-and-regurgitation-in-congenital-heart-disease-and-pulmonary-hypertension-comparison-of-4d-flow-cardiovascular-magnetic-resonance-and-echocardiography
#5
Mieke M P Driessen, Marjolijn A Schings, Gertjan Tj Sieswerda, Pieter A Doevendans, Erik H Hulzebos, Marco C Post, Repke J Snijder, Jos J M Westenberg, Arie P J van Dijk, Folkert J Meijboom, Tim Leiner
BACKGROUND: Tricuspid valve (TV) regurgitation (TR) is a common complication of pulmonary hypertension and right-sided congenital heart disease, associated with increased morbidity and mortality. Estimation of TR severity by echocardiography and conventional cardiovasvular magnetic resonance (CMR) is not well validated and has high variability. 4D velocity-encoded (4D-flow) CMR was used to measure tricuspid flow in patients with complex right ventricular (RV) geometry and varying degrees of TR...
January 15, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29332249/correlation-of-flow-density-as-measured-using-optical-coherence-tomography-angiography-with-structural-and-functional-parameters-in-glaucoma-patients
#6
Maged Alnawaiseh, Larissa Lahme, Viktoria Müller, André Rosentreter, Nicole Eter
PURPOSE: To evaluate the correlation between flow density, as measured by optical coherence tomography angiography (OCTA), and structural and functional parameters in patients with open-angle glaucoma. METHODS: Thirty-four eyes of 34 patients with open-angle glaucoma and 35 eyes of 35 healthy subjects were prospectively included in this study. OCTA was performed using RTVue XR Avanti with AngioVue. The macula was imaged with a 3 × 3 mm scan and the optic nerve head (ONH) with a 4...
January 13, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29331846/functional-neuroimaging-in-rasmussen-syndrome
#7
Ichiro Kuki, Kazumi Matsuda, Yuko Kubota, Tetsuhiro Fukuyama, Yukitoshi Takahashi, Yushi Inoue, Haruo Shintaku
PURPOSE: For a diagnosis of Rasmussen syndrome (RS), clinical course together with electroencephalography (EEG) and magnetic resonance imaging (MRI) findings are considered important, but there are few reports on functional neuroimaging. This study investigated cerebral blood flow (CBF)-single photon emission computed tomography (SPECT), central benzodiazepine receptor (BZR)-SPECT, and fluorine-18 fluorodeoxy glucose-positron emission tomography (FDG-PET) in RS patients, and correlated neuroimaging results with MRI and pathological findings...
January 5, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29331358/assessing-risk-category-of-breast-cancer-by-ultrasound-imaging-characteristics
#8
Qiang Guo, Lei Zhang, Zhixin Di, Chunping Ning, Zhiwu Dong, Ziyao Li, Dongmo Wang, Chong Liu, Ming Zhao, Jiawei Tian
The purpose of our study was to assess the potential clinical value of ultrasound imaging in predicting risk category in patients with breast cancer. Three hundred thirty-six patients were enrolled and divided into a high-risk group (99, 29.5%) and mid- to low-risk group (237, 70.5%) according to the St. Gallen risk criteria. All data were retrospectively collected to analyze correlations between ultrasound features and risk category. The results revealed that the ultrasound features of irregular shape (p= 0...
January 10, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29331053/renal-flow-and-microstructure-anisotropy-refmap-mri-in-normal-and-peritumoral-renal-tissue
#9
Andrea L Liu, Artem Mikheev, Henry Rusinek, William C Huang, James S Wysock, James S Babb, Thorsten Feiweier, David Stoffel, Hersh Chandarana, Eric E Sigmund
BACKGROUND: Diffusion-weighted imaging (DWI) provides insight into the pathophysiology underlying renal dysfunction. Variants of DWI include intravoxel incoherent motion (IVIM), which differentiates between microstructural diffusion and vascular or tubular flow, and diffusion tensor imaging (DTI), which quantifies diffusion directionality. PURPOSE: To investigate the reproducibility of joint IVIM-DTI and compare controls to presurgical renal mass patients. STUDY TYPE: Prospective cross-sectional...
January 13, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29330407/multiscale-and-luminescent-hollow-microspheres-for-gas-phase-thermometry
#10
Lothar Bischoff, Michael Stephan, Christina S Birkel, Christian F Litterscheid, Andreas Dreizler, Barbara Albert
Recently developed laser-based measurement techniques are used to image the temperatures and velocities in gas flows. They require new phosphor materials with an unprecedented combination of properties. A novel synthesis procedure is described here; it results in hierarchically structured, hollow microspheres of Eu3+-doped Y2O3, with unusual particle sizes and very good characteristics compared to full particles. Solution-based precipitation on polymer microballoons produces very stable and luminescent, ceramic materials of extremely low density...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329818/hybrid-imaging-in-ischemic-heart-disease
#11
Andreas A Giannopoulos, Oliver Gaemperli
Hybrid imaging for ischemic heart disease refers to the fusion of information from a single or usually from multiple cardiovascular imaging modalities enabling synergistic assessment of the presence, the extent, and the severity of coronary atherosclerotic disease along with the hemodynamic significance of lesions and/or with evaluation of the myocardial function. A combination of coronary computed tomography angiography with myocardial perfusion imaging, such as single-photon emission computed tomography and positron emission tomography, has been adopted in several centers and implemented in international coronary artery disease management guidelines...
January 9, 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29329733/association-between-leukoaraiosis-and-cerebral-blood-flow-territory-alteration-in-asymptomatic-internal-carotid-artery-stenosis
#12
Y-F Chen, Y-S Kuo, W-C Wu, S-C Tang, S-F Jiang
AIM: To test the hypothesis that leukoaraiosis (also known as white matter lesion) is associated with cerebral blood flow territory change as revealed by territorial arterial spin-labeling (TASL) magnetic resonance imaging (MRI) in patients with asymptomatic internal carotid artery stenosis (aICAS). MATERIALS AND METHODS: The institutional review board approved this study. Thirty-three patients with aICAS were included prospectively and divided into high-grade (ultrasonographic stenosis ≥70%, n=17) and low-grade (n=16) groups; 16 healthy subjects were also included...
January 9, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29329053/long-term-safety-area-tracking-lt-sat-with-online-failure-detection-and-recovery-for-robotic-minimally-invasive-surgery
#13
Veronica Penza, Xiaofei Du, Danail Stoyanov, Antonello Forgione, Leonardo S Mattos, Elena De Momi
Despite the benefits introduced by robotic systems in abdominal Minimally Invasive Surgery (MIS), major complications can still affect the outcome of the procedure, such as intra-operative bleeding. One of the causes is attributed to accidental damages to arteries or veins by the surgical tools, and some of the possible risk factors are related to the lack of sub-surface visibilty. Assistive tools guiding the surgical gestures to prevent these kind of injuries would represent a relevant step towards safer clinical procedures...
December 22, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/29328505/substance-p-as-a-putative-efferent-transmitter-mediates-gabaergic-inhibition-in-mouse-taste-buds
#14
Anthony Y Huang, Sandy Y Wu
BACKGROUND AND PURPOSE: Capsaicin-mediated modulation on taste nerve responses is thought to be produced indirectly by actions of neuropeptides, e.g., calcitonin gene-related peptide (CGRP) and substance P (SP), onto taste cells implying playing a role in taste sensitivity. During processing gustatory information in taste buds, CGRP shapes peripheral taste signals via serotonergic signaling. The underlying assumption has been that SP exerts its effects on taste transmitter secretion in taste buds of mice...
January 12, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29328268/backscatter-particle-image-velocimetry-via-optical-time-of-flight-sectioning
#15
Megan E Paciaroni, Yi Chen, Kyle P Lynch, Daniel R Guildenbecher
Conventional particle image velocimetry (PIV) configurations require a minimum of two optical access ports, inherently restricting the technique to a limited class of flows. Here, the development and application of a novel method of backscattered time-gated PIV requiring a single-optical-access port is described along with preliminary results. The light backscattered from a seeded flow is imaged over a narrow optical depth selected by an optical Kerr effect (OKE) time gate. The picosecond duration of the OKE time gate essentially replicates the width of the laser sheet of conventional PIV by limiting detected photons to a narrow time-of-flight within the flow...
January 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29326979/nanometer-precision-linear-sorting-with-synchronized-optofluidic-dual-barriers
#16
Yuzhi Shi, Sha Xiong, Lip Ket Chin, Jingbo Zhang, Wee Ser, Jiuhui Wu, Tianning Chen, Zhenchuan Yang, Yilong Hao, Bo Liedberg, Peng Huat Yap, Din Ping Tsai, Cheng-Wei Qiu, Ai Qun Liu
The past two decades have witnessed the revolutionary development of optical trapping of nanoparticles, most of which deal with trapping stiffness larger than 10-8 N/m. In this conventional regime, however, it remains a formidable challenge to sort out sub-50-nm nanoparticles with single-nanometer precision, isolating us from a rich flatland with advanced applications of micromanipulation. With an insightfully established roadmap of damping, the synchronization between optical force and flow drag force can be coordinated to attempt the loosely overdamped realm (stiffness, 10-10 to 10-8 N/m), which has been challenging...
January 2018: Science Advances
https://www.readbyqxmd.com/read/29326419/evaluation-of-multislice-spiral-computed-tomography-perfusion-imaging-for-the-efficacy-of-preoperative-concurrent-chemoradiotherapy-in-middle-aged-and-elderly-patients-with-locally-advanced-gastric-cancer
#17
Jian-Xiao Liang, Xiu-Juan Bi, Xiao-Mei Li, Zhen-Li Gao, Feng Suo, En-Gang Cui, Hong-Fu Li, Hai-Lian Lv
BACKGROUND This study aimed to investigate the predictive value of multislice spiral computed tomography (MSCT) perfusion imaging for the efficacy of preoperative concurrent chemoradiotherapy (CCRT) in middle-aged and elderly patients with locally advanced gastric cancer (LAGC). MATERIAL AND METHODS One-hundred twenty-six middle-aged and elderly patients with LAGC were selected. MSCT was performed before and after CCRT to obtain perfusion parameters: blood flow volume (BF), blood volume (BV), mean transit time (MTT), and permeability surface (PS)...
January 12, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29326360/immunopet-in-inflammatory-bowel-disease-imaging-cd4-t-cells-in-a-murine-model-of-colitis
#18
Amanda Christine Freise, Kirstin A Zettlitz, Felix Bergara Salazar, Richard Tavaré, Wen-Ting K Tsai, Arion Hadjioannou, Nora Rozengurt, Jonathan Braun, Anna M Wu
Inflammatory bowel diseases (IBD) in humans are characterized in part by aberrant CD4+ T cell responses. Currently, identification of foci of inflammation within the gut requires invasive procedures such as colonoscopy and biopsy. Molecular imaging with antibody fragment probes could be used to noninvasively monitor cell subsets causing intestinal inflammation. Here, GK1.5 cys-diabody (cDb), an anti-mouse CD4 antibody fragment derived from the GK1.5 hybridoma, was used as a positron emission tomography (PET) probe for CD4+ T cells in the dextran sulfate sodium (DSS) mouse model of IBD...
January 11, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29326138/cerebellar-hypoperfusion-in-migraine-attack-incidence-and-significance
#19
F Kellner-Weldon, M El-Koussy, S Jung, M Jossen, P P Klinger-Gratz, R Wiest
BACKGROUND AND PURPOSE: Patients diagnosed with migraine with aura have an increased lifetime risk of ischemic stroke. It is not yet clear whether prolonged cortical hypoperfusion during an aura increases the immediate risk of cerebellar infarction because it may induce crossed cerebellar diaschisis and subsequent tissue damage. To address this question, we retrospectively analyzed potential relationships between cortical oligemia and cerebellar hypoperfusion in patients with migraine with aura and their potential relation to small infarct-like cerebellar lesions...
January 11, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29325958/novel-assessment-of-cerebrospinal-fluid-dynamics-by-time-spatial-labeling-inversion-pulse-magnetic-resonance-imaging-in-patients-with-chiari-malformation-type-i
#20
Tatsuya Ohtonari, Nobuharu Nishihara, Shinzo Ota, Akio Tanaka
OBJECTIVE: We investigated CSF dynamics at CCJ using Time-SLIP MRI to demonstrate the significance of ventral and dorsal combined CSF dynamics in assessing CSF flow disturbance in patients with CM-I. METHODS: Fifteen examinations were performed in nine cases of CM-I (three females patients; mean age, 24.7 years; age range, 11-46 years) before or after craniocervical decompression. The longitudinal maximum movement of the caudal edge of tagged mid-sagittal CSF at CCJ was measured as a LOM, and total on the ventral and dorsal sides was defined as total LOM...
January 8, 2018: World Neurosurgery
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