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https://www.readbyqxmd.com/read/29151182/electrical-cardioversion-of-patients-with-implanted-pacemaker-or-cardioverter-defibrillator-results-of-a-survey-of-german-centers-and-systematic-review-of-the-literature
#1
J Lüker, A Sultan, T Plenge, J van den Bruck, C-H Heeger, S Meyer, K Mischke, R R Tilz, D Vollmann, G Nölker, B Schäffer, S Willems, D Steven
AIMS: A relevant number of patients presenting for electrical cardioversion carry a pacemaker (PM) or ICD. Case reports suggest a potential hazard of external cardioversion/defibrillation. The incidence of shock related device complications is unknown. No guidelines or recommendations by international medical societies for a cardioversion protocol of cardiovascular implantable electronic device (CIED) patients exist. We conducted a nationwide survey to gather real-world clinical data on the current clinical approach towards these patients during electrical cardioversion and to estimate the incidence of shock-related complications...
November 18, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29141184/unrecognized-venous-injuries-after-cardiac-implantable-electronic-device-transvenous-lead-extraction
#2
Khaldoun G Tarakji, Walid Saliba, Danny Markabawi, E Rene Rodriguez, Yoaav Krauthammer, Michael P Brunner, Ayman A Hussein, Bryan Baranowski, Daniel J Cantillon, Mohamed Kanj, Mark Niebauer, Jack Rickard, Thomas Callahan, Mingyuan Shao, David O Martin, Oussama M Wazni, Bruce L Wilkoff, Carmela D Tan
BACKGROUND: Major complication rate of transvenous lead extraction (TLE) is estimated around 1-2.0%. Laceration of the central veins can be fatal. OBJECTIVES: to define the incidence and extent of venous injuries on a microscopic level after TLE and compare it with the incidence of clinically documented events of venous laceration. METHODS: We studied all patients who underwent TLE at our tertiary center within 30 months via a variety of techniques...
November 7, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29138937/effects-of-propofol-sedation-on-pacing-thresholds-results-from-an-observational-cohort-study
#3
Jakob Lüker, Arian Sultan, Tobias Plenge, Samuel Lee, Jan-Hendrik van den Bruck, Daniel Steven
BACKGROUND: Propofol is one of the most commonly used intravenous anaesthetic drugs for surgical procedures. The use of propofol for sedation is also common practice during endoscopic procedures, electrophysiology studies, and ablation procedures, as well as pacemaker and defibrillator implantation. It was found that propofol alters the electrophysiologic properties of the heart and its conduction system. The effects of propofol on pacing thresholds are unknown and could have implications for pacemaker (PM) and defibrillator (ICD) implantation procedures, as well as sedation and anaesthesia in PM and ICD patients in general...
November 14, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29138413/oscillators-that-sync-and-swarm
#4
Kevin P O'Keeffe, Hyunsuk Hong, Steven H Strogatz
Synchronization occurs in many natural and technological systems, from cardiac pacemaker cells to coupled lasers. In the synchronized state, the individual cells or lasers coordinate the timing of their oscillations, but they do not move through space. A complementary form of self-organization occurs among swarming insects, flocking birds, or schooling fish; now the individuals move through space, but without conspicuously altering their internal states. Here we explore systems in which both synchronization and swarming occur together...
November 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/29133067/-subacute-myocardial-perforation-related-to-a-pacemaker-lead-case-report-and-literature-review
#5
Jorge González, Luisa Aguilera, Carlos Gutiérrez, Guillermo Delgado, Efrain Gaxiola
Myocardial perforation related to cardiac electronic devices leads is a rare, but unfortunate complication, since its clinical implications are potentially lethal. The fluoroscopic outcome of case of subacute right ventricular perforation is presented, together with an analysis based on a literature review.
November 10, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/29128861/atrial-cardiomyopathy-in-an-adult-labrador-retriever-dog
#6
E Bomassi, J Rousselot, S Libermann, I Raymond Letron, S Etchepareborde, C Misbach
A 7-year-old castrated male Labrador retriever was examined for a 10-day history of weakness and syncope. Physical examination revealed bradycardia and a grade III/VI left apical systolic heart murmur. Electrocardiography demonstrated bradycardia, absence of P waves and an atrio-ventricular nodal escape rhythm. Echocardiography revealed marked biatrial enlargement. Thoracic radiographs showed no evidence of pulmonary edema. Routine plasma biochemistry and electrolytes, basal serum cortisol, total thyroxin concentration, and complete blood count were within normal limits...
November 2017: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29124430/oversensing-of-the-wearable-cardioverter-defibrillator-during-bipolar-ventricular-stimulation
#7
Martin Manninger, Tanja Odeneg, Friedrich Fruhwald, Helmut Brussee, Daniel Scherr
The wearable cardioverter defibrillator (WCD) is a temporary treatment option for patients with potentially reversible risk of sudden cardiac death. This case demonstrates a pitfall during WCD usage in a pacemaker-dependent patient as well as a possible solution allowing continuation of WCD therapy. Bipolar stimulation may lead to double counting of the WCD detection algorithm resulting in false alarm or inappropriate therapy.
November 9, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29120136/postoperative-atrial-fibrillation-prophylaxis-and-lung-resection-%C3%A2-our-experience-with-608-consecutive-patients
#8
Vjekoslav Karadža, Dinko Stančić-Rokotov, Jasna Špiček Macan, Nevenka Hodoba, Nevenka Kolarić, Sanja Sakan
Postoperative atrial fibrillation is a common complication after lung resection. It is burdened by increased mortality and morbidity, prolonged hospitalization, and higher resource utilization in thoracic surgery patients. Therefore, some kind of pharmacological prophylaxis is recommended. In our patients, diltiazem, a calcium antagonist, is administered. We collected data on all 608 patients having undergone lung resection (no less than lobectomy) between November 2012 and May 2015. This period included patients having received diltiazem during their postoperative stay in our Intensive Care Unit and surgical ward, and those that did not receive it...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29114383/placement-of-cardiac-pacemaker-trial-pocket-rationale-and-design-a-randomized-controlled-trial
#9
Peter Magnusson, Leo Wennström, Robert Kastberg, Per Liv
Background: A pacemaker system consists of one or two leads connected to a device that is implanted into a pocket formed just below the collarbone. This pocket is typically subcutaneous, that is, located just above the pectoral fascia. Even though the size of pacemakers has decreased markedly, complications due to superficial implants do occur. An alternative technique would be intramuscular placement of the pacemaker device, but there are no randomized controlled trials (RCTs) to support this approach, which is the rationale for the Placement Of Cardiac PacemaKEr Trial (POCKET)...
January 2017: Heart International
https://www.readbyqxmd.com/read/29110935/successful-percutaneous-retrieval-of-a-leadless-pacemaker-due-to-an-acute-rise-in-pacing-threshold
#10
Ngai-Yin Chan, Ho-Chuen Yuen, Ngai-Shing Mok
Leadless cardiac pacemakers (LCP) have become available recently. Both its acute and long-term performance in a large population of patients remain to be tested. Subacute rise in pacing threshold has been reported as an uncommon complication. On the other hand, the retrieval technique for LCP with passive fixation mechanism has not been previously described in details. Herein we report a newly recognized complication of an acute rise in pacing threshold very soon after implantation of an LCP without radiographic dislodgement...
October 28, 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29109881/hypothermia-with-extreme-bradycardia-following-spinal-cord-infarction-of-septic-origin
#11
Philippe Hantson, Thierry Duprez
Among other autonomic dysfunctions complicating acute spinal cord injury, deep hypothermia is rare but may induce serious cardiovascular complications. There are few pharmacological options to influence hypothermia. A 66-year-old woman was transferred to the intensive care unit (ICU) for serious cardiac arrhythmias (atrial fibrillation and asystole) in the context of a deep hypothermia (axillary temperature below 32°C). She had been admitted to the hospital two months before for an acute L4-L5 infectious spondylodiscitis without any initial neurological deficit...
2017: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/29107716/pacsin-2-is-required-for-the-maintenance-of-a-normal-cardiac-function-in-the-developing-mouse-heart
#12
Judith Semmler, Jan Kormann, Sureshkumar Perumal Srinivasan, Annette Köster, Daniel Sälzer, Michael Reppel, Jürgen Hescheler, Markus Plomann, Filomain Nguemo
The Pacsin proteins (Pacsin 1, 2 and 3) play an important role in intracellular trafficking and thereby signal transduction in many cells types. This study was designed to examine the role of Pacsin 2 in cardiac development and function. We investigated the development and electrophysiological properties of Pacsin 2 knockout (P2KO) hearts and single cardiomyocytes isolated from 11.5 and 15.5days old fetal mice. Immunofluorescence experiments confirmed the lack of Pacsin 2 protein expression in P2KO cardiac myocytes in comparison to wildtype (WT)...
October 28, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29104560/in-a-heartbeat-light-and-cardiovascular-physiology
#13
REVIEW
Sarah L Chellappa, Ruta Lasauskaite, Christian Cajochen
Light impinging on the retina fulfils a dual function: it serves for vision and it is required for proper entrainment of the endogenous circadian timing system to the 24-h day, thus influencing behaviors that promote health and optimal quality of life but are independent of image formation. The circadian pacemaker located in the suprachiasmatic nuclei modulates the cardiovascular system with an intrinsic ability to anticipate morning solar time and with a circadian nature of adverse cardiovascular events. Here, we infer that light exposure might affect cardiovascular function and provide evidence from existing research...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29104201/-cardiac-perforation-after-pacemaker-implantation-report-of-a-case
#14
Yuko Ohashi, Kazuhiro Ohkura, Ayano Yamada
A 71-year-old woman was diagnosed with sick sinus syndrome (SSS) upon her cardiogenic cerebral embolism and underwent pacemaker implantation. Active fixation leads were positioned at the right atrial appendage and ventricular septum. Twenty-one days later at her routine checkup, she was asymptomatic and there were no signs of cardiac tamponade or pacing failure. But echocardiography and computed tomography revealed a large amount of pericardial effusion due to the lead perforation. We performed open drainage because her anticoagulant could not be stopped for her history of cerebral infarction...
November 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29103011/seizure-triggered-by-sick-sinus-syndrome
#15
Nilesh Patel, Faisal Majeed, Anupam Ashutosh Sule
Sick sinus syndrome (SSS) is a dysfunction of sinoatrial node resulting in symptomatic bradycardia or sinus pauses causing decreased cardiac output with cerebral hypoperfusion and usually presents as syncope, presyncope or fatigue. The occurrence of a seizure is very rare. A 69-year-old man suffered two episodes of generalised tonic-clonic seizures. MRI and electroencephalogram failed to reveal the cause of seizures. In the emergency room, he experienced presyncope simultaneous to bradycardia and sinus pauses...
November 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29102688/beating-heart-mitral-valve-repair-using-a-novel-eptfe-cordal-implantation-device-prospective-trial
#16
James S Gammie, Krzysztof Bartus, Andrzej Gackowski, Michael N D'Ambra, Piotr Szymanski, Agata Bilewska, Mariusz Kusmierczyk, Boguslaw Kapelak, Jolanta Rzucidlo-Resil, Neil Moat, Alison Duncan, Rashmi Yadev, Steve Livesey, Paul Diprose, Gino Gerosa, Augusto D'Onofrio, Demetrio Pitterello, Paolo Denti, Giovanni La Canna, Michele De Bonis, Ottavio Alfieri, Judy Hung, Piotr Kolsut
BACKGROUND: We evaluated safety and performance of the Harpoon Mitral Valve Repair System (H-MVRS), a transesophageal echocardiographic-guided device designed to implant artificial expanded polytetrafluoroethylene (ePTFE) cords on mitral leaflets in the beating heart. METHODS: In a prospective multicenter study, 30 consecutive patients with severe degenerative mitral regurgitation (MR) were treated with H-MVRS via small left thoracotomy. The primary (30 day) endpoint was successful implantation of cords with MR reduction to moderate or less...
October 26, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29097735/mammalian-%C3%AE-2-ampk-regulates-intrinsic-heart-rate
#17
Arash Yavari, Mohamed Bellahcene, Annalisa Bucchi, Syevda Sirenko, Katalin Pinter, Neil Herring, Julia J Jung, Kirill V Tarasov, Emily J Sharpe, Markus Wolfien, Gabor Czibik, Violetta Steeples, Sahar Ghaffari, Chinh Nguyen, Alexander Stockenhuber, Joshua R St Clair, Christian Rimmbach, Yosuke Okamoto, Dongmei Yang, Mingyi Wang, Bruce D Ziman, Jack M Moen, Daniel R Riordon, Christopher Ramirez, Manuel Paina, Joonho Lee, Jing Zhang, Ismayil Ahmet, Michael G Matt, Yelena S Tarasova, Dilair Baban, Natasha Sahgal, Helen Lockstone, Rathi Puliyadi, Joseph de Bono, Owen M Siggs, John Gomes, Hannah Muskett, Mahon L Maguire, Youlia Beglov, Matthew Kelly, Pedro P N Dos Santos, Nicola J Bright, Angela Woods, Katja Gehmlich, Henrik Isackson, Gillian Douglas, David J P Ferguson, Jürgen E Schneider, Andrew Tinker, Olaf Wolkenhauer, Keith M Channon, Richard J Cornall, Eduardo B Sternick, David J Paterson, Charles S Redwood, David Carling, Catherine Proenza, Robert David, Mirko Baruscotti, Dario DiFrancesco, Edward G Lakatta, Hugh Watkins, Houman Ashrafian
AMPK is a conserved serine/threonine kinase whose activity maintains cellular energy homeostasis. Eukaryotic AMPK exists as αβγ complexes, whose regulatory γ subunit confers energy sensor function by binding adenine nucleotides. Humans bearing activating mutations in the γ2 subunit exhibit a phenotype including unexplained slowing of heart rate (bradycardia). Here, we show that γ2 AMPK activation downregulates fundamental sinoatrial cell pacemaker mechanisms to lower heart rate, including sarcolemmal hyperpolarization-activated current (I f) and ryanodine receptor-derived diastolic local subsarcolemmal Ca(2+) release...
November 2, 2017: Nature Communications
https://www.readbyqxmd.com/read/29090491/clinical-safety-and-performance-of-a-mri-conditional-pacing-system-in-patients-undergoing-cardiac-mri
#18
Chi Keong Ching, Rabindra Nath Chakraborty, Tarlochan Singh Kler, Satchana Pumprueg, Tachapong Ngarmukos, Joseph Yat Sun Chan, Sumit Anand, Rakesh Yadav, Surapun Sitthisook, Ka Wing Yim, Rakesh K Jaswal, Kartikeya Bhargava
BACKGROUND: Utilization of cardiac Magnetic Resonance Imaging (cMRI) as an imaging modality in clinical practice is rapidly increasing. More evidence from randomized studies establishing clinical safety and performance of pacing systems in patients undergoing a cMRI scan is needed. OBJECTIVES: The purpose of this prospective, multi-center, randomized study was to demonstrate safety and efficacy of the Accent MRIۛ conditional pacing systems in patients undergoing cMRI scan...
November 1, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29090490/the-effect-of-an-ultra-low-framerate-and-antiscatter-grid-less-radiation-protocol-for-cardiac-device-implantations
#19
Philipp Attanasio, Tobias Schreiber, Abdul Parwani, Philipp Lacour, Burkert Pieske, Wilhelm Haverkamp, Florian Blaschke, Martin Huemer
BACKGROUND AND AIMS: Antiscatter grids improve image contrast by absorbing scattered X-ray beams. By removing the antiscatter grid patient dose can be reduced as more X-ray beams reach the image receptor. Additionally there is a trend towards ultra low framerates for radiation dose reduction during various EP procedures. As for most cardiac device implantations (CIED) image quality demands are usually modest, the purpose of this study was to assess the safety and efficacy of an ultra-low frame rate and scatter grid-less radiation protocol...
November 1, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29081396/beneficial-effects-of-upgrading-to-his-bundle-pacing-in-chronically-paced-patients-with-left-ventricular-ejection-fraction-50
#20
Peiren Shan, Lan Su, Xiaodong Zhou, Shengjie Wu, Lei Xu, Fangyi Xiao, Xiaohong Zhou, Kenneth A Ellenbogen, Weijian Huang
BACKGROUND: Heart failure is common in patients with permanent pacemakers. Right ventricular (RV) pacing may worsen cardiac function while non-responder rate of cardiac resynchronization therapy (CRT) for heart failure treatment remains 25-30%. OBJECTIVE: This study was to assess clinical outcomes of upgrading to permanent His bundle pacing (pHBP) in heart failure patients who underwent device upgrade from RV pacing or CRT non-response. METHODS: Eighteen pacing-dependent heart failure patients with left ventricular ejection fraction (LVEF) <50% underwent pHBP attempts at device replacement...
October 25, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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