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https://www.readbyqxmd.com/read/28529181/leadless-cardiac-pacemakers-current-status-of-a-modern-approach-in-pacing
#1
REVIEW
Skevos Sideris, Stefanos Archontakis, Polychronis Dilaveris, Konstantinos A Gatzoulis, Konstantinos Trachanas, Ilias Sotiropoulos, Petros Arsenos, Dimitrios Tousoulis, Ioannis Kallikazaros
Since the first transvenous pacemaker implantation, that took place 50 years ago, important progress has been achieved in pacing technology. Consequently, today, more than 700,000 pacemakers are implanted annually worldwide. However, conventional pacemakers' implantation carries a non-negligible risk of periprocedural and long-term complications associated with the transvenous leads and pacemaker pocket. Recently, Leadless Pacing Systems have emerged as a therapeutic alternative to conventional pacing systems providing therapy for patients with bradyarrhythmias, while eliminating potential transvenous leads and pacemaker pocket related complications...
May 18, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28515825/late-presentation-of-aortic-aneurysm-and-dissection-following-cardiac-catheterization
#2
Abimbola Shofu, G Mustafa Awan, Bassam Omar, Ghazanfar Qureshi
We report a 63-year-old female with hypertension, hyperlipidemia, and prior pacemaker insertion for atrial fibrillation with symptomatic bradycardia, who was admitted with substernal chest pressure and diaphoresis. Her electrocardiogram revealed atrial fibrillation with demand ventricular pacing and her cardiac biomarkers were negative for acute coronary syndrome. Echocardiogram revealed normal left ventricular systolic function and normal aortic root diameter. Coronary angiography revealed 60-70% obtuse marginal lesion, otherwise mild disease...
April 2017: Cardiology Research
https://www.readbyqxmd.com/read/28512722/status-of-cardiovascular-pet-radiation-exposure-and-strategies-for-reduction-an-information-statement-from-the-cardiovascular-pet-task-force
#3
James A Case, Robert A deKemp, Piotr J Slomka, Mark F Smith, Gary V Heller, Manuel D Cerqueira
Cardiovascular positron emission tomography (PET) imaging provides high-quality visual and quantitative myocardial perfusion and function images. In addition, cardiovascular PET can assess myocardial viability, myocardial inflammatory disorders such as cardiac sarcoid, and infections of implanted devices including pacemakers, ventricular assist devices, and prosthetic heart valves. As with all nuclear cardiology procedures, the benefits need to be considered in relation to the risks of exposure to radiation...
May 16, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28512364/-radiographic-implications-of-procedures-involving-cardiac-implantable-electronic-devices-cieds-selected-aspects
#4
Roman Steckiewicz, Dariusz Artur Kosior, Elżbieta Barbara Świętoń, Marek Rosiak, Bartosz Lange, Przemysław Stolarz
BACKGROUND: Some cardiac implantable electronic device (CIED) implantation procedures require the use of X-rays, which is reflected by such parameters as total fluoroscopy time (TFT) and dose-area product (DAP - defined as the absorbed dose multiplied by the area irradiated). MATERIAL AND METHODS: This retrospective study evaluated 522 CIED implantation (424 de novo and 98 device upgrade and new lead placement) procedures in 176 women and 346 men (mean age 75±11 years) over the period 2012-2015...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28511925/total-correction-of-tetralogy-of-fallot-at-early-age-a-study-of-183-cases
#5
Mohamed Alassal, Bedir M Ibrahim, Hany M Elrakhawy, Magdy Hassenien, Sameh Sayed, Magdy Elshazly, Nabil Elsadeck
BACKGROUND: Opinions regarding the optimal time for the repair of tetralogy of Fallot vary. A debate also exists about the timing of repair for the asymptomatic infant. METHODS: This study included 183 patients with tetralogy of Fallot. All patients were subjected to clinical examination with measurement of oxygen saturation, 12-lead ECG, plain chest x-ray, and complete laboratory investigation. Echocardiography and cardiac catheterisation were indicated if there was an inability to reach diagnosis by echocardiography, suspicion of coronary anomaly, evaluation of distal pulmonary arteries or suspicion of major aorto-pulmonary collaterals...
April 27, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28511449/management-of-accidental-and-iatrogenic-foreign-body-injuries-to-heart-case-series
#6
REVIEW
Rupesh Kumar, Sandeep Singh Rana, Sanjay Kumar, Deepanwita Das, Monalisa Datta
Accidental and iatrogenic foreign body injuries to heart require immediate attention and its timely management is cornerstone to the life of an individual. We describe in detail five cases of Accidental and iatrogenic foreign body injuries to heart encountered between January 2013 and July 2016. Our series included the following: needle stick injury to the right atrium (1 case) retained catheter fragments in the distal main pulmonary artery (1 case), right ventricle injury during catheterisation study (1 case), right ventricle injury during permanent pacemaker lead placement (1 case), device migration in atrial septal defect closure (1 case)...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28506648/antegrade-versus-continuous-retrograde-del-nido-cardioplegia-in-the-david-i-operation
#7
Xuan Jiang, Tianxiang Gu, Enyi Shi, Chun Wang, Zongyi Xiu, Guangwei Zhang
BACKGROUND: The efficacy of continuous retrograde del Nido cardioplegia for myocardial protection is still controversial. We hypothesised that antegrade and retrograde cardioplegia offer equivalent safety for myocardial protection in the David I procedure. METHODS: We retrospectively reviewed 33 patients undergoing the David I operation with antegrade or retrograde del Nido solution from June 2014 to January 2016. The outcomes were compared. The follow-up was 1 month to 15 months...
April 26, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28503840/a-critical-note-on-treatment-of-a-severe-diltiazem-intoxication-high-dose-calcium-and-glucagon-infusions
#8
N M Van Veggel, G J Van der Veen, T C Jansen, E M Westerman
The morbidity and mortality of a severe calcium channel blocker intoxication is high due to serious toxic cardiac effects. Its treatment is supported by low-quality evidence from heterogeneous literature. We describe a case of a severe diltiazem intoxication and critically appraise the efficacy and role of high-dose calcium and glucagon infusions. A 53-year-old woman was admitted to the emergency department with a cardiogenic shock with complete AV block, not responding to atropine, isoprenaline and an external pacemaker...
May 15, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28502871/a-leadless-pacemaker-in-the-real-world-setting-the-micra-transcatheter-pacing-system-post-approval-registry
#9
Paul R Roberts, Nicolas Clementy, Faisal Al Samadi, Christophe Garweg, Jose Luis Martinez-Sande, Saverio Iacopino, Jens Brock Johansen, Xavier Vinolas Prat, Robert Kowal, Didier Klug, Lluis Mont, Jan Steffel, Shelby Li, Dirk Van Osch, Mikhael F El-Chami
BACKGROUND: First-in-man studies of leadless pacemakers have demonstrated high implant success rates, and safety and efficacy objectives were achieved. Outside of the investigational setting, there are particular concerns over cardiac effusion/perforation, device dislodgement, infection, telemetry, and battery issues. OBJECTIVE: The acute performance of the Micra transcatheter pacemaker from a worldwide post-approval registry is reported. METHODS: The registry is an ongoing prospective single-arm observational study designed to assess the safety and effectiveness of Micra in the post-approval setting...
May 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28500812/the-prevalence-of-chagas-disease-among-latin-american-immigrants-with-pacemakers-in-los-angeles-california
#10
Sandy Park, Daniel R Sanchez, Mahmoud I Traina, Jason S Bradfield, Salvador Hernandez, Alvaro Joaquin Altamirano Ufion, Jalal Dufani, Patrick Bergin, Robin Y Wachsner, Sheba K Meymandi
AbstractChagas disease (CD), with associated conduction abnormalities, is a common indication for pacemaker implantation in Latin America. The prevalence of CD in Latin American immigrants with pacemakers residing in the United States has never been studied. This single-center cross-sectional study included pacemaker patients who were aged 18 years or more with a previous residence in Latin America for at least 6 months. Patients with an implantable cardioverter-defibrillator, cardiac resynchronization therapy, or iatrogenic and/or congenital heart block were excluded...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28500172/induced-pluripotent-stem-cell-derived-cardiomyocytes-provide-in-vivo-biological-pacemaker-function
#11
Samuel Chauveau, Evgeny P Anyukhovsky, Meital Ben-Ari, Shulamit Naor, Ya-Ping Jiang, Peter Danilo, Tania Rahim, Stephanie Burke, Xiaoliang Qiu, Irina A Potapova, Sergey V Doronin, Peter R Brink, Ofer Binah, Ira S Cohen, Michael R Rosen
BACKGROUND: Although multiple approaches have been used to create biological pacemakers in animal models, induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have not been investigated for this purpose. We now report pacemaker function of iPSC-CMs in a canine model. METHODS AND RESULTS: Embryoid bodies were derived from human keratinocytes, their action potential characteristics determined, and their gene expression profiles and markers of differentiation identified...
May 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28496930/percutaneous-vacuum-assisted-thrombectomy-device-used-for-removal-of-large-vegetations-on-infected-pacemaker-and-defibrillator-leads-as-an-adjunct-to-lead-extraction
#12
Raymond H M Schaerf, Sasan Najibi, John Conrad
This case series reports our early experience with a minimally invasive percutaneous method of safely removing large vegetations during lead extraction in septic cardiac implantable electronic devices (CIED). Debate exists concerning the management of vegetations involving these devices. Lead extraction is mandated for infections, but vegetations may embolize, causing complications. Surgical debridement is recommended; alternatives include cardiopulmonary bypass, minimally invasive thoracotomy, or transatrial approaches...
October 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/28496929/management-of-patients-with-atrial-fibrillation-focus-on-treatment-options
#13
REVIEW
Pawel Matusik, Jacek Lelakowski, Barbara Malecka, Jacek Bednarek, Remigiusz Noworolski
Atrial fibrillation (AF) is leading cardiac arrhythmia with important clinical implications. Its diagnosis is usually made on the basis on 12-lead ECG or 24-hour Holter monitoring. More and more clinical evidence supports diagnostic use of cardiac event recorders and cardiovascular implantable electronic devices (CIED). Treatment options in patients with atrial fibrillation are extensive and are based on chosen rhythm and/or rate control strategy. The use and selected contraindications to AF related pharmacotherapy, including anticoagulants are shown...
October 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/28495655/increased-sodium-calcium-exchanger-activity-enhances-beta-adrenergic-mediated-increase-in-heart-rate-whole-heart-study-in-a-homozygous-sodium-calcium-exchanger-overexpressor-mouse-model
#14
Sven Kaese, Nils Bögeholz, Paul Pauls, Dirk Dechering, Jan Olligs, Katharina Kölker, Sascha Badawi, Gerrit Frommeyer, Christian Pott, Lars Eckardt
BACKGROUND: The cardiac Na(+)/Ca(2+)-exchanger (NCX) contributes to diastolic depolarization in cardiac pacemaker cells. Increased NCX activity has been found in heart failure and atrial fibrillation. So far, the influence of increased NCX activity on resting heart rate, beta-adrenergic mediated increase in heart rate and cardiac conduction properties is unknown. OBJECTIVE: This study therefore investigates the influence of NCX overexpression in a homozygous transgenic whole-heart mouse model (NCX-OE) on sinus and AV nodal function...
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28491705/implantation-of-a-leadless-cardiac-pacemaker-for-recurrent-pocket-infections
#15
Philip M Chang, Rahul N Doshi
No abstract text is available yet for this article.
July 2016: HeartRhythm Case Reports
https://www.readbyqxmd.com/read/28490521/survival-in-women-versus-men-following-implantation-of-pacemakers-defibrillators-and-cardiac-resynchronization-therapy-devices-in-a-large-nationwide-cohort
#16
Niraj Varma, Suneet Mittal, Julie B Prillinger, Jeff Snell, Nirav Dalal, Jonathan P Piccini
BACKGROUND: Whether outcomes differ between sexes following treatment with pacemakers (PM), implantable cardioverter defibrillators, and cardiac resynchronization therapy (CRT) devices is unclear. METHODS AND RESULTS: Consecutive US patients with newly implanted PM, implantable cardioverter defibrillators, and CRT devices from a large remote monitoring database between 2008 and 2011 were included in this observational cohort study. Sex-specific all-cause survival postimplant was compared within each device type using a multivariable Cox proportional hazards model, stratified on age and adjusted for remote monitoring utilization and ZIP-based socioeconomic variables...
May 10, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28489502/advances-in-cardiac-pacing-and-defibrillation
#17
Kristin Ellison, Parikshit S Sharma, Richard Trohman
There have been many milestones in the evolution of cardiac implantable electronic devices (CIEDs) over the past few decades. Along with advancements in the field, new challenges have arisen. The ability to pace the right ventricular was the original breakthrough in the late 1950s, however adverse structural and clinical effects of long-term pacing induced dyssynchrony have recently become evident. Biventricular pacing has provided a viable option to help mitigate dyssynchrony, but has only proved to be beneficial for selective patients (primarily left bundle branch block and QRS duration ≥ 150 ms with depressed left ventricular (LV) function)...
May 10, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28484359/evaluation-of-congenital-heart-defects-treatment-options-establishment-of-pediatric-cardiology-cardiosurgery-in-bosnia-and-herzegovina
#18
REVIEW
Zijo Begic, Sanko Pandur, Edo Omerbasic, Almira Kadic, Mirza Halimic
INTRODUCTION: Modern pediatric cardiology mainly deals with congenital heart defects (CHD), as the most common congenital anomalies. In most cases CHD requires surgical or interventional treatment. GOAL: The goal of the research was to evaluate CHD treatment at Pediatric Clinic, University Clinical Center (UCC) Sarajevo, Bosnia and Herzegovina (B&H). UCC Sarajevo is the only institution in B&H where cardiac treatment of CHD in pediatric population is performed. Pediatric cardiosurgery has started to develop in Bosnia and Herzegovina in April 1997...
March 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/28483438/construction-of-vascularized-pacemaker-tissues-by-seeding-cardiac-progenitor-cells-and-endothelial-progenitor-cells-into-matrigel
#19
Luping Zhang, Xiaotong Li, Xiaolong Yu, Yuquan Li, Aijun Sun, Chao Huang, Feng Xu, Jinping Guo, Yao Sun, Xi Zhang, Xiangqun Yang, Chuansen Zhang
AIMS: Transplantation of a tissue engineered cardiac pacemaker (TECP) may represent a novel therapy for cardiac sinus node dysfunction. We previously reported that cardiac progenitor cells (CPCs) derived from embryonic heart tubes could differentiate into cardiac pacemaking cells after endothelin-1 treatment. We aimed to examine the feasibility of TECP fabricated from CPCs-derived pacemaking cells and vascularization of TECP fabricated from CPCs-derived pacemaking cells and endothelial progenitor cells (EPCs) in vitro and in vivo implantation...
May 5, 2017: Life Sciences
https://www.readbyqxmd.com/read/28481822/two-hearts-synchronized-each-other-with-a-ddd-pacemaker
#20
Michele Brunacci, Alberto Valbusa, Claudio Brunelli, Giovanni Bertero
: We describe the case of a patient with dyspnea and heterotopic cardiac transplant, ventricular fibrillation from the native heart and sinus rhythm from the transplanted one. The two hearts were synchronized with a pacemaker. Electric external cardioversion and a different type of pacemaker stimulation were successfully performed, with improving symptoms.
December 2016: Journal of Cardiovascular Medicine
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