keyword
MENU ▼
Read by QxMD icon Read
search

Anti-aging Medicine

keyword
https://www.readbyqxmd.com/read/28425415/drug-induced-liver-injury-at-a-tertiary-hospital-in-india-etiology-clinical-features-and-predictors-of-mortality
#1
Chetan Rathi, Nirav Pipaliya, Ruchir Patel, Meghraj Ingle, Aniruddha Phadke, Prabha Sawant
INTRODUCTION AND AIMS: Drug-induced liver injury (DILI) is rare; however, it is one of the important causes of acute liver failure which results in significant morbidity or mortality. MATERIAL AND METHODS: Patients with suspected DILI were enrolled based on predefined criteria and followed up for at least 6 months or until normalization of liver tests. Causality assessment was done by applying the Roussel Uclaf Causality Assessment Method model. RESULTS: We collected data from 82 individuals diagnosed with DILI at our hospital from 2014 through 2015 (41 men; median age, 38 years)...
May 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28420905/effects-of-supervised-aerobic-training-on-the-levels-of-anti-mullerian-hormone-and-adiposity-measures-in-women-with-normo-ovulatory-and-polycystic-ovary-syndrome
#2
Einas Al-Eisa, Sami Ali Gabr, Ahmad Hieder Alghadir
OBJECTIVE: To evaluate the change in the levels of anti-Mullerian hormone, adiponectin, weight loss and fertility parameters in obese women with or without polycystic ovary syndrome, following 12 weeks of supervised aerobic exercise. METHODS: This study was conducted from August 2013 to October 2014 among obese women with or without polycystic ovary syndrome referred to Obstetrics and Gynecology clinic, Mansoura University Hospital, Faculty of Medicine, Mansoura, Egypt...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28413327/effects-of-ginseng-on-two-main-sex-steroid-hormone-receptors-estrogen-and-androgen-receptors
#3
REVIEW
Joonwoo Park, Heewon Song, Si-Kwan Kim, Myeong Soo Lee, Dong-Kwon Rhee, YoungJoo Lee
Ginseng has been used in China for at least two millennia and is now popular in over 35 countries. It is one of the world's popular herbs for complementary and alternative medicine and has been shown to have helpful effects on cognition and blood circulation, as well as anti-aging, anti-cancer, and anti-diabetic effects, among many others. The pharmacological activities of ginseng are dependent mainly on ginsenosides. Ginsenosides have a cholesterol-like four trans-ring steroid skeleton with a variety of sugar moieties...
April 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28411325/a-literature-update-elucidating-production-of-panax-ginsenosides-with-a-special-focus-on-strategies-enriching-the-anti-neoplastic-minor-ginsenosides-in-ginseng-preparations
#4
REVIEW
Tanya Biswas, A K Mathur, Archana Mathur
Ginseng, an oriental gift to the world of healthcare and preventive medicine, is among the top ten medicinal herbs globally. The constitutive triterpene saponins, ginsenosides, or panaxosides are attributed to ginseng's miraculous efficacy towards anti-aging, rejuvenating, and immune-potentiating benefits. The major ginsenosides such as Rb1, Rb2, Rc, Rd., Re, and Rg1, formed after extensive glycosylations of the aglycone "dammaranediol," dominate the chemical profile of this genus in vivo and in vitro. Elicitations have successfully led to appreciable enhancements in the production of these major ginsenosides...
April 14, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28395936/efficacy-of-mepolizumab-add-on-therapy-on-health-related-quality-of-life-and-markers-of-asthma-control-in-severe-eosinophilic-asthma-musca-a-randomised-double-blind-placebo-controlled-parallel-group-multicentre-phase-3b-trial
#5
Geoffrey L Chupp, Eric S Bradford, Frank C Albers, Daniel J Bratton, Jie Wang-Jairaj, Linda M Nelsen, Jennifer L Trevor, Antoine Magnan, Anneke Ten Brinke
BACKGROUND: Mepolizumab, an anti-interleukin-5 monoclonal antibody approved as add-on therapy to standard of care for patients with severe eosinophilic asthma, has been shown in previous studies to reduce exacerbations and dependency on oral corticosteroids compared with placebo. We aimed to further assess mepolizumab in patients with severe eosinophilic asthma by examining its effect on health-related quality of life (HRQOL). METHODS: We did a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial (MUSCA) in 146 hospitals or research centres in 19 countries worldwide...
April 5, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28392456/anti-inflammatory-activity-of-crateva-adansonii-dc-on-keratinocytes-infected-by-staphylococcus-aureus-from-traditional-practice-to-scientific-approach-using-hptlc-densitometry
#6
Kplolali Ahama-Esseh, Charles Bodet, Akossiwa Quashie-Mensah-Attoh, Magali Garcia, Isabelle Théry-Koné, Joelle Dorat, Comlan De Souza, Cécile Enguehard-Gueiffier, Leslie Boudesocque-Delaye
ETHNOPHARMACOLIGICAL RELEVANCE: Leaves of Crateva adansonii DC (Capparidaceae), a small bush found in Togo, are widely used in traditional medicine to cure infectious abscesses. Traditional healers of Lomé harvest only budding leaves early in the morning, in specific area in order to prepare their drugs. AIM OF THE STUDY: The main goal was to validate the ancestral picking practices, and to assess the activity of C. adansonii medicine towards infectious abscesses...
April 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28384465/multicenter-retrospective-study-of-the-risk-factors-of-hemorrhage-after-tooth-extraction-in-patients-receiving-antiplatelet-therapy
#7
Souichi Yanamoto, Takumi Hasegawa, Satoshi Rokutanda, Sayaka Komori, Akira Tachibana, Yuka Kojima, Yoshito Koyama, Yasuyuki Shibuya, Hiroshi Kurita, Takahide Komori, Masahiro Umeda
PURPOSE: To identify the risk factors affecting hemorrhage after tooth extraction in patients receiving antiplatelet therapy, this study investigated the relation between various factors and hemorrhage events after tooth extraction. PATIENTS AND METHODS: The records of 264 patients receiving antiplatelet therapy who underwent tooth extraction were retrospectively reviewed from 6 institutions belonging to the Japanese Study Group of Cooperative Dentistry with Medicine...
March 14, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28363525/protective-effect-of-a-phenolic-extract-containing-indoline-amides-from-portulaca-oleracea-against-cognitive-impairment-in-senescent-mice-induced-by-large-dose-of-d-galactose-nano2
#8
Peipei Wang, Hongxiang Sun, Dianyu Liu, Zezhao Jiao, Su Yue, Xiuquan He, Wen Xia, Jianbo Ji, Lan Xiang
ETHNOPHARMACOLOGICAL RELEVANCE: Portulaca oleracea L. is a potherb and also a widely used traditional Chinese medicine. In accordance with its nickname "longevity vegetable", pharmacological study demonstrated that this plant possessed antioxidant, anti-aging, and cognition-improvement function. Active principles pertaining to these functions of P. oleracea need to be elucidated. AIM OF THE STUDY: The present study evaluated the effect of a phenolic extract (PAAs) from P...
May 5, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28360931/mechanisms-for-the-anti-obesity-actions-of-bofutsushosan-in-high-fat-diet-fed-obese-mice
#9
Shinjiro Kobayashi, Yuki Kawasaki, Tatsuo Takahashi, Hironori Maeno, Masaaki Nomura
BACKGROUND: The Kampo medicine bofutsushosan (BTS; Pulvis ledebouriellae compositae; Fang Feng Tong Sheng San) has been used as an anti-obesity treatment in overweight patients. In this study, we assessed the underlying physiological changes induced by BTS in obese mice maintained on a high-fat diet. METHODS: Male ICR mice were fed a 60% kcal fat diet for 5 weeks starting at 4 weeks of age and then fed the same diet with administration of water (control) or aqueous BTS extract (1...
2017: Chinese Medicine
https://www.readbyqxmd.com/read/28359197/mechanisms-of-traditional-chinese-medicine-in-the-treatment-of-mammary-gland-hyperplasia
#10
Xiaoliang Li, Ping Xin, Changfu Wang, Zhibin Wang, Qiuhong Wang, Haixue Kuang
Mammary gland hyperplasia (MGH) occurs with high frequency among middle-aged women and is closely related to breast cancer. The treatment of this disease has become a research hotspot. Many patients with MGH are worried about the potential side effects of the synthetic drugs they are on. Thus, they seek alternative therapy, such as traditional Chinese medicine (TCM). In recent years, along with the Chinese herbs and its active ingredients, TCM compounds have been widely accepted and implemented in the treatment of MGH, whose mechanism hitherto is not completely clear...
March 30, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28358008/modified-sjh-alleviates-ffas-induced-hepatic-steatosis-through-leptin-signaling-pathways
#11
Dong-Woo Lim, Shambhunath Bose, Jing-Hua Wang, Han Seok Choi, Young-Mi Kim, Young-Won Chin, Song-Hee Jeon, Jai-Eun Kim, Hojun Kim
Samjunghwan (SJH) is an herbal formula used in traditional Korean medicine. This prescription has long been used in treatment of aging and lifestyle diseases. The current study showed the effect and mechanisms of anti-hepatic steatosis action of modified SJH (mSJH) in vitro and in vivo. Treatment with mSJH resulted in significantly decreased intracellular lipid accumulation in steatosis-induced cells. Furthermore, mSJH triggered the phosphorylation of AMP-activated protein kinase and acetyl-CoA carboxylase as well as increased the expression of leptin at both protein and gene levels...
March 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28352332/inhibitory-effect-of-salvia-plebeia-leaf-extract-on-ultraviolet-induced-photoaging-associated-ion-channels-and-enzymes
#12
You-Jin Chang, Dong-Ung Lee, Da Yeong Nam, Sung Min Cho, Seungug Hong, Joo Hyun Nam, Woo Kyung Kim
In traditional Korean/Asian medicine, Salvia plebeia R.Br. (S. plebeia) leaves are used to treat inflammatory diseases, including dermatitis, cough, asthma and toothache. Recently, S. plebeia leaves have been applied in skin care, as they promote skin lightening and elasticity. Therefore, the present study investigated the anti-aging effects of S. plebeia leaf methanolic extract and its fractions (dichloromethane, ethylacetate and n-butanol). The results of a whole-cell patch clamp analysis indicated that the methanolic extract mediated ultraviolet (UV)-induced photoaging-associated ion channels, transient receptor potential vanilloid 1 (TRPV1) and calcium release-activated calcium channel protein 1 (ORAI1) channel activity in HEK293T cells overexpressing TRPV1 or ORAI1 and STIM1...
February 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28352315/daphnetin-inhibits-inflammation-in-the-nzb-w-f1-systemic-lupus-erythematosus-murine-model-via-inhibition-of-nf-%C3%AE%C2%BAb-activity
#13
Min Li, Xiaowei Shi, Fangru Chen, Fei Hao
Daphnetin is a compound extracted from Chinese medicinal herbs, which exerts analgesic and anti-inflammatory effects. The present study aimed to investigate the potential therapeutic effect of daphnetin on inflammation in the NZB/W F1 systemic lupus erythematosus (SLE) murine model. Female NZB/WF1 mice (age, 16-18 weeks) were intraperitoneally injected with daphnetin once a day for 12 weeks. It was revealed that daphnetin treatment significantly increased animal survival rates, reduced renal damage and blood urea nitrogen levels, and suppressed serum autoantibody production in the SLE-prone NZB/W F1 mice...
February 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28349587/lycium-barbarum-polysaccharides-extracts-preserve-retinal-function-and-attenuate-inner-retinal-neuronal-damage-in-a-mouse-model-of-transient-retinal-ischemia
#14
Di Yang, Kwok-Fai So, Amy C Y Lo
PURPOSE: Retinal ischemia is a common feature shared by numerous eye diseases. Ischemic insult leads to retinal dysfunction and neuronal death. Lycium barbarum polysaccharides (LBP), extracts from an anti-aging and anti-oxidation Oriental medicine, are well known for eyesight preservation. We have previously reported the effect of LBP on cell death, blood ocular barrier and oxidative stress within 24 hours in a mouse model of retinal ischemia. This study focuses on retinal function and looks for ultrastructural and cellular correlates after a relatively long period of reperfusion for 7 days...
March 27, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28347832/the-genus-achyranthes-a-review-on-traditional-uses-phytochemistry-and-pharmacological-activities
#15
REVIEW
Xirui He, Xiaoxiao Wang, Jiacheng Fang, Yu Chang, Ning Ning, Hao Guo, Linhong Huang, Xiaoqiang Huang
ETHNOPHARMACOLOGICAL RELEVANCE: Achyranthes L. (Amaranthaceae), also known as Chaff Flower and Niuxi/, mainly includes two famous medicinal species namely A. bidentata and A. aspera. A. bidentata has been widely used as blood-activating and stasis-resolving medicine for the treatment of various diseases including amenorrhea, dysmenorrhea, lumbago, gonalgia, paraplegia, edema, stranguria, headache, dizziness, odontalgia, oral ulcer, hematemesis, and epistaxis. A. aspera has been widely used to treat various diseases, including gynecological disorder, asthma, ophthalmia, odontalgia, haemorrhoids, and abdominal tumor, and has been applied to difficult labour, wound healing, insect and snake bites...
May 5, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28336272/apigenin-7-diglucuronide-protects-retinas-against-bright-light-induced-photoreceptor-degeneration-through-the-inhibition-of-retinal-oxidative-stress-and-inflammation
#16
Minjuan Bian, Yong Zhang, Xiaoye Du, Jing Xu, Jingang Cui, Jiangping Gu, Weiliang Zhu, Teng Zhang, Yu Chen
Vision impairment in retinal degenerative diseases such as age-related macular degeneration is primarily associated with photoreceptor degeneration, in which oxidative stress and inflammatory responses are mechanistically involved as central players. Therapies with photoreceptor protective properties remain to be developed. Apigenin-7-diglucuronide (A7DG), a flavonoid glycoside, is present in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. However, the pharmacological significance of A7DG remains unknown in vivo...
March 20, 2017: Brain Research
https://www.readbyqxmd.com/read/28334832/the-n-glycosylation-of-immunoglobulin-g-as-a-novel-biomarker-of-parkinson-s-disease
#17
Alyce C Russell, Mirna Šimurina, Monique T Garcia, Mislav Novokmet, Youxin Wang, Igor Rudan, Harry Campbell, Gordan Lauc, Meghan G Thomas, Wei Wang
The use of the emerging "omics" technologies for large scale population screening is promising in terms of predictive, preventive and personalized medicine. For Parkinson's disease, it is essential that an accurate diagnosis is obtained and disease progression can be monitored. Immunoglobulin G (IgG) has the ability to exert both anti-inflammatory and pro-inflammatory effects, and the N-glycosylation of the fragment crystallizable portion of IgG is involved in this process. This study aimed to determine whether the IgG glycome could be a candidate biomarker for Parkinson's disease...
May 1, 2017: Glycobiology
https://www.readbyqxmd.com/read/28320100/drosophila-melanogaster-a-potential-model-organism-for-identification-of-pharmacological-properties-of-plants-plant-derived-components
#18
REVIEW
Komal Panchal, Anand K Tiwari
Plants/plant-derived components have been used from ancient times to treat/cure several human diseases. Plants and their parts possess several chemical components that play the vital role in the improvement of human health and their life expectancy. Allopathic medicines have been playing a key role in the treatment of several diseases. Though allopathic medicines provide fast relief, long time consumption cause serious health concerns such as hyperallergic reactions, liver damage, etc. So, the study of medicinal plants which rarely cause any side effect is very important to mankind...
March 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28301050/addition-of-anti-leukotriene-agents-to-inhaled-corticosteroids-for-adults-and-adolescents-with-persistent-asthma
#19
REVIEW
Bhupendrasinh F Chauhan, Maya M Jeyaraman, Amrinder Singh Mann, Justin Lys, Ahmed M Abou-Setta, Ryan Zarychanski, Francine M Ducharme
BACKGROUND: Asthma management guidelines recommend low-dose inhaled corticosteroids (ICS) as first-line therapy for adults and adolescents with persistent asthma. The addition of anti-leukotriene agents to ICS offers a therapeutic option in cases of suboptimal control with daily ICS. OBJECTIVES: To assess the efficacy and safety of anti-leukotriene agents added to ICS compared with the same dose, an increased dose or a tapering dose of ICS (in both arms) for adults and adolescents 12 years of age and older with persistent asthma...
March 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28300445/botanicals-with-dermatologic-properties-derived-from-first-nations-healing
#20
Sophia Colantonio, Jason K Rivers
INTRODUCTION: First Nations people have a long history of working with medicinal plants used to treat skin diseases. The purpose was to assess the dermatologic therapeutic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce. METHODS: Based on expert recommendations, 5 trees were selected that were used in First Nations medicine for cutaneous healing and have potential and/or current application to dermatology today. We searched several databases up to June 12, 2014...
February 1, 2017: Journal of Cutaneous Medicine and Surgery
keyword
keyword
91713
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"