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https://www.readbyqxmd.com/read/28092514/a-multivariate-approach-for-patient-specific-eeg-seizure-detection-using-empirical-wavelet-transform
#1
Abhijit Bhattacharyya, Ram Bilas Pachori
OBJECTIVE: This paper investigates the multivariate oscillatory nature of electroencephalogram (EEG) signals in adaptive frequency scales for epileptic seizure detection. METHODS: The empirical wavelet transform (EWT) has been explored for the multivariate signals in order to determine the joint instantaneous amplitudes and frequencies in signal adaptive frequency scales. The proposed multivariate extension of EWT has been studied on multivariate multi-component synthetic signal, as well as on multivariate EEG signals of CHB-MIT scalp EEG database...
January 9, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28091337/assessing-the-social-and-environmental-determinants-of-pertussis-epidemics-in-queensland-australia-a-bayesian-spatio-temporal-analysis
#2
X Huang, S Lambert, C Lau, R J Soares Magalhaes, J Marquess, M Rajmokan, G Milinovich, W Hu
Pertussis epidemics have displayed substantial spatial heterogeneity in countries with high socioeconomic conditions and high vaccine coverage. This study aims to investigate the relationship between pertussis risk and socio-environmental factors on the spatio-temporal variation underlying pertussis infection. We obtained daily case numbers of pertussis notifications from Queensland Health, Australia by postal area, for the period January 2006 to December 2012. A Bayesian spatio-temporal model was used to quantify the relationship between monthly pertussis incidence and socio-environmental factors...
January 16, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28080071/nanoscale-engineering-in-vo2-nanowires-via-direct-electron-writing-process
#3
Zhenhua Zhang, Hua Guo, Wenqiang Ding, Bin Zhang, Yue Lu, Xiaoxing Ke, Weiwei Liu, Fu-Rong Chen, Manling Sui
Controlling phase transition in functional materials at nano-scale is not only of broad scientific interest, but also important for practical applications in the fields of renewable energy, information storage, transducer, sensor, etc. As a model functional material, vanadium dioxide (VO2) has its metal-insulator transition (MIT) usually at a sharp temperature around 68 °C. Here we report a focused electron beam can directly lower down the transition temperature of a nano-area to room temperature without pre-patterning the VO2...
January 12, 2017: Nano Letters
https://www.readbyqxmd.com/read/28068499/metacognitive-interpersonal-therapy-for-personality-disorders-swinging-from-emotional-over-regulation-to-dysregulation-a-case-study
#4
Giampalo Salvatore, Raffaele Popolo, Luisa Buonocore, Anna Maria Ferrigno, Mariagrazia Proto, Anna Sateriale, Marianna Serio, Giancarlo Dimaggio
Many patients with personality disorders (PD) display emotional inhibition or over-regulation (EOR); others display emotional dysregulation (ED)- heightened sensitivity to emotional stimuli with difficulty toning down arousal. To date, most treatments focus on patients with ED, particularly those with borderline disorders, though some focus on EOR. Patients with complex PD often swing from periods of EOR to ED. In this paper, we describe an adaptation of metacognitive interpersonal therapy (MIT), which has been manualized for treating PD with prominent EOR and is aimed at dealing with patients fluctuating from EOR to ED...
December 31, 2016: American Journal of Psychotherapy
https://www.readbyqxmd.com/read/28061368/modeling-of-the-photoplethysmogram-during-atrial-fibrillation
#5
Andrius Sološenko, Andrius Petrėnas, Vaidotas Marozas, Leif Sörnmo
A phenomenological model for simulating the photoplethysmogram (PPG) during atrial fibrillation (AF) is proposed. The simulated PPG is solely based on RR interval information, and, therefore, any annotated ECG database can be used to model sinus rhythm, AF, or rhythms with premature beats. A PPG pulse is modeled by a linear combination of a log-normal and two Gaussian waveforms. The model PPG is obtained by placing individual pulses according to the RR intervals so that a connected signal is created. The model is evaluated on synchronously recorded ECG and PPG signals from the MIMIC and the University of Queensland Vital Signs Dataset databases...
December 28, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28055987/heart-beat-classification-from-single-lead-ecg-using-the-synchrosqueezing-transform
#6
Christophe L Herry, Martin Frasch, Andrew Je Seely, Hau-Tieng Wu
The processing of ECG signal provides a wealth of information on cardiac function and overall cardiovascular health. While multi-lead ECG recordings are often necessary for a proper assessment of cardiac rhythms, they are not always available or practical, for example in fetal ECG applications. Moreover, a wide range of small non-obtrusive single-lead ECG ambulatory monitoring devices are now available, from which heart rate variability (HRV) and other health-related metrics are derived. Proper beat detection and classification of abnormal rhythms is important for reliable HRV assessment and can be challenging in single-lead ECG monitoring devices...
January 5, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28048283/we-h-204-03-part-2-history-and-archives-resources-at-aip-for-aapm-and-its-members
#7
M Mueller
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047523/we-h-204-00-history-committee-symposium
#8
Michael Gossman
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046866/we-h-204-01-william-d-coolidge-inventor-of-the-modern-x-ray-tube
#9
D Allard
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046206/we-h-204-02-part-1-history-and-archives-resources-at-aip-for-aapm-and-its-members
#10
G Good
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28038313/critical-behavior-in-doping-driven-metal-insulator-transition-on-single-crystalline-organic-mott-fet
#11
Yoshiaki Sato, Yoshitaka Kawasugi, Masayuki Suda, Hiroshi M Yamamoto, Reizo Kato
We present the carrier transport properties in the vicinity of a doping-driven Mott transition observed at a field-effect transistor (FET) channel using a single crystal of the typical two-dimensional organic Mott insulator κ-(BEDT-TTF)2CuN(CN)2Cl (κ-Cl). The FET shows a continuous metal-insulator transition (MIT) as electrostatic doping proceeds. The phase transition appears to involve two-step crossovers, one in Hall measurement and the other in conductivity measurement. The crossover in conductivity occurs around the conductance quantum e(2)/h, and hence is not associated with 'bad metal' behavior, in stark contrast to the MIT in half-filled organic Mott insulators or that in doped inorganic Mott insulators...
December 30, 2016: Nano Letters
https://www.readbyqxmd.com/read/28031184/svscore-an-impact-prediction-tool-for-structural-variation
#12
Liron Ganel, Haley J Abel, Ira M Hall
: Here we present SVScore, a tool for in silico structural variation (SV) impact prediction. SVScore aggregates per-base single nucleotide polymorphism (SNP) pathogenicity scores across relevant genomic intervals for each SV in a manner that considers variant type, gene features and positional uncertainty. We show that the allele frequency spectrum of high-scoring SVs is strongly skewed toward lower frequencies, suggesting that they are under purifying selection, and that SVScore identifies deleterious variants more effectively than alternative methods...
December 28, 2016: Bioinformatics
https://www.readbyqxmd.com/read/28029262/photocurrent-switching-of-monolayer-mos2-using-a-metal-insulator-transition
#13
Jin Hee Lee, Hamza Zad Gul, Hyun Kim, Byoung Hee Moon, Subash Adhikari, Jung Ho Kim, Homin Choi, Young Hee Lee, Seong Chu Lim
We achieve switching on/off the photocurrent of monolayer molybdenum disulfide (MoS2) by controlling the metal-insulator transition (MIT). N-type semiconducting MoS2 under a large negative gate bias generates a photocurrent attributed to the increase of excess carriers in the conduction band by optical excitation. However, under a large positive gate bias, a phase shift from semiconducting to metallic MoS2 is caused, and the photocurrent by excess carriers in the conduction band induced by the laser disappears due to enhanced electron-electron scattering...
January 3, 2017: Nano Letters
https://www.readbyqxmd.com/read/28028497/providing-an-efficient-algorithm-for-finding-r-peaks-in-ecg-signals-and-detecting-ventricular-abnormalities-with-morphological-features
#14
Mohammad Pooyan, Fateme Akhoondi
Ventricular arrhythmias are one of the most important causes of annual deaths in the world, which may lead to sudden cardiac deaths. Accurate and early diagnosis of ventricular arrhythmias in heart diseases is essential for preventing mortality in cardiac patients. Ventricular activity on the electrocardiogram (ECG) signal is in the interval from the beginning of QRS complex to T wave end. Variations in the ECG signal and its features may indicate heart condition of patients. The first step to extract features of ECG in time domain is finding R peaks...
October 2016: Journal of Medical Signals and Sensors
https://www.readbyqxmd.com/read/28026762/learning-multi-instance-deep-discriminative-patterns-for-image-classification
#15
Peng Tang, Xinggang Wang, Bin Feng, Wenyu Liu
Finding an effective and efficient representation is very important for image classification. The most common approach is to extract a set of local descriptors, and then aggregate them into a high-dimensional, more semantic feature vector, like unsupervised Bag-of-Features (BoF) and weakly supervised partbased models. The later one is usually more discriminative than the former due to the use of information from image labels. In this work, we propose a weakly supervised strategy that using Multi-Instance Learning (MIL) to learn discriminative patterns for image representation...
December 21, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28025760/targeting-specificity-protein-1-transcription-factor-and-survivin-using-tolfenamic-acid-for-inhibiting-ewing-sarcoma-cell-growth
#16
Sagar Shelake, Umesh T Sankpal, W Paul Bowman, Matthew Wise, Anish Ray, Riyaz Basha
Transcription factor Specificity protein 1 (Sp1) and its downstream target survivin (inhibitor of apoptosis protein), play major roles in the pathogenesis of various cancers. Ewing Sarcoma (ES) is a common soft tissue/bone tumor in adolescent and young adults. Overexpression of survivin is also linked to the aggressiveness and poor prognosis of ES. Small molecule Tolfenamic acid (TA) inhibits Sp1 and survivin in cancer cells. In this investigation, we demonstrate a strategy to target Sp1 and survivin using TA and positive control Mithramycin A (Mit) to inhibit ES cell growth...
December 26, 2016: Investigational New Drugs
https://www.readbyqxmd.com/read/28024443/pennatz-c-m-a-the-brain-s-representational-power-on-consciousness-and-the-integration-of-modalities-pennatz-c-m-a-the-brain-s-representational-power-on-consciousness-and-the-integration-of-modalities-cambridge-ma-mit-press-2016-400-pp-isbn-9780262029315-%C3%A2-35
#17
https://www.readbyqxmd.com/read/28009155/three-dimensional-printing-of-shape-memory-composites-with-epoxy-acrylate-hybrid-photopolymer
#18
Ran Yu, Xin Yang, Ying Zhang, Xiaojuan Zhao, Xiao Wu, Tingting Zhao, Yulei Zhao, Wei Huang
Four-dimensional printing, a new process to fabricate active materials through three-dimensional (3D) printing developed by MIT's Self-Assembly Lab in 2014, has attracted more and more research and development interests recently. In this paper, a type of epoxy-acrylate hybrid photopolymer was synthesized and applied to fabricate shape memory polymers through a stereolithography 3D printing technique. The glass-to-rubbery modulus ratio of the printed sample determined by dynamic mechanical analysis is as high as 600, indicating that it may possess good shape memory properties...
January 6, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28003430/conformational-changes-in-inhibitory-pas-domain-protein-associated-with-binding-of-hif-1%C3%AE-and-bcl-xl-in-living-cells
#19
Shuya Kasai, Shinji Kajimoto, Yuma Ito, Tomo Saito, Ken-Ichi Yasumoto, Makio Tokunaga, Kumiko Sakata-Sogawa, Hiroshi Fukumura, Kazuhiro Sogawa
Inhibitory PAS domain protein (IPAS) is a dual function protein acting as a transcriptional repressor and as a pro-apoptotic protein. Simultaneous dual-color single-molecule imaging of EGFP-IPAS coexpressed with Mit-TagRFP-T in living HeLa cells revealed that fraction of EGFP-IPAS was arrested in the nucleus and on mitochondria. Transiently expressed Cerulean-IPAS in HEK293T cells was present in nuclear speckles when coexpressed with Citrine-HIF-1α or Citrine-HLF. Fluorescence lifetime imaging microscopy (FLIM) analysis of Citrine-IPAS-Cerulean in living CHO-K1 cells clarified the presence of intramolecular FRET...
December 21, 2016: Journal of Biochemistry
https://www.readbyqxmd.com/read/27997573/genetic-characterization-of-circulating-2015-a-h1n1-pdm09-influenza-viruses-from-eastern-india
#20
Anupam Mukherjee, Mukti Kant Nayak, Shanta Dutta, Samiran Panda, Biswa Ranjan Satpathi, Mamta Chawla-Sarkar
In 2015, the swine derived A(H1N1)pdm09 pandemic strain outbreak became widespread throughout the different states of India. The reported cases and deaths in 2015 surpassed the previous years with more than 39000 laboratory confirmed cases and a death toll of more than 2500 people. There are relatively limited complete genetic sequences available for this virus from Asian countries. In this study, we describe the full genome analysis of influenza 2015 A(H1N1)pdm09 viruses isolated from West Bengal between January through December 2015...
2016: PloS One
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