keyword
MENU ▼
Read by QxMD icon Read
search

Cambridge

keyword
https://www.readbyqxmd.com/read/28429768/reassembling-embryos-in-vitro-from-component-stem-cells
#1
Caroline Kubaczka, George Q Daley
Researchers at the University of Cambridge, UK have succeeded in reconstructing mouse embryos by combining pluripotent embryonic and multipotent trophoblast stem cells in a 3D scaffold; the study from the laboratory of Professor Zernicka-Goetz, recently published in Science, provides a break-through tool to probe early mammalian development outside the uterus. Achieving a similar feat with human cells might necessitate reconsideration of the 14-day rule as a limitation of such research.
April 21, 2017: Cell Research
https://www.readbyqxmd.com/read/28429582/obesity-and-addiction-can-a-complication-of-surgery-help-us-understand-the-connection
#2
REVIEW
V Ivezaj, L E Stoeckel, N M Avena, S C Benoit, A Conason, J F Davis, A N Gearhardt, R Goldman, J E Mitchell, C N Ochner, K K Saules, K J Steffen, E Stice, S Sogg
Obesity is a multifactorial, chronic disease that has proven difficult to treat. An increased understanding of aetiological mechanisms is critical to the development of more effective obesity prevention and treatment strategies. A growing body of empirical evidence has demonstrated parallels between obesity, overeating and substance abuse, including shared behavioural, psychological and neurophysiological factors implicated in the excessive intake of both food and substances of abuse. Several different lines of research have recently emerged that hold the potential to shed light on the connection between obesity, food reward and addiction, with studies examining changes in alcohol use/misuse after weight loss surgery providing a particularly interesting perspective on these interrelationships...
April 21, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28427310/kernell-d-colours-and-colour-vision-an-introductory-survey-kernell-d-colours-and-colour-vision-an-introductory-survey-united-kingdom-cambridge-university-press-2016-271-pp-isbn-9781107083035-%C3%A2-64-99-hardcover
#3
https://www.readbyqxmd.com/read/28427309/pennatz-c-m-a-the-brain-s-representational-power-on-consciousness-and-the-integration-of-modalities-pennatz-c-m-a-the-brain-s-representational-power-on-consciousness-and-the-integration-of-modalities-cambridge-ma-mit-press-2016-400-pp-isbn-9780262029315-%C3%A2-35
#4
https://www.readbyqxmd.com/read/28425298/understanding-self-reported-difficulties-in-decision-making-by-people-with-autism-spectrum-disorders
#5
Lydia Vella, Howard A Ring, Mike Rf Aitken, Peter C Watson, Alexander Presland, Isabel Ch Clare
Autobiographical accounts and a limited research literature suggest that adults with autism spectrum disorders can experience difficulties with decision-making. We examined whether some of the difficulties they describe correspond to quantifiable differences in decision-making when compared to adults in the general population. The participants (38 intellectually able adults with autism spectrum disorders and 40 neurotypical adults) were assessed on three tasks of decision-making (Iowa Gambling Task, Cambridge Gamble Task and Information Sampling Task), which quantified, respectively, decision-making performance and relative attention to negative and positive outcomes, speed and flexibility, and information sampling...
April 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28425185/the-influence-of-hippocampal-atrophy-on-the-cognitive-phenotype-of-dementia-with-lewy-bodies
#6
Greg J Elder, Karen Mactier, Sean J Colloby, Rosie Watson, Andrew M Blamire, John T O'Brien, John-Paul Taylor
OBJECTIVE: The level of hippocampal atrophy in dementia with Lewy bodies (DLB) is typically less than that observed in Alzheimer's disease (AD). However, it is not known how the cognitive phenotype of DLB is influenced by hippocampal atrophy or the atrophy of adjacent medial temporal lobe structures. METHODS: Dementia with Lewy bodies (n = 65), AD (n = 76) and control (n = 63) participants underwent 3T magnetic resonance imaging and cognitive Cambridge Cognitive Examination and Mini-Mental State Examination (CAMCOG and MMSE) assessments...
April 20, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28422813/a-new-approach-in-assessing-core-muscle-endurance-using-ratings-of-perceived-exertion
#7
James D George, Jeffrey R Tolley, Pat R Vehrs, Joel D Reece, M Fatih Akay, Edward D J Cambridge
This study sought to develop regression models to estimate maximal endurance time by using data from four core muscle endurance tests. Eighty healthy university students (age: 22.7 ± 1.9 yr) performed the plank, right side-bridge, left side-bridge, and back extension tests in a random order. Participants were instructed to hold each static position for a maximal endurance time, while maintaining proper form, and then rest for 5 min between tests. A test administrator recorded participants' ratings of perceived exertion (RPE; modified 10-point scale) every 5 s...
April 4, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28421667/serum-levels-of-wisteria-floribunda-agglutinin-positive-mac-2-binding-protein-reflect-the-severity-of-chronic-pancreatitis
#8
Takashi Fujiyama, Tetsuhide Ito, Keijiro Ueda, Yuichi Tachibana, Kohei Yasunaga, Masami Miki, Takehiro Takaoka, Lingaku Lee, Ken Kawabe, Yoshihiro Ogawa
AIM: To evaluate the utility of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA(+) -M2BP) level as a marker for chronic pancreatitis (CP). METHODS: We measured serum WFA(+) -M2BP level of 74 patients with CP who had undergone endoscopic retrograde cholangiopancreatography (ERCP) and 30 normal controls (NC) using the glycan sugar chain-based immunoassay and examined the relationship between serum WFA(+) -M2BP level and Cambridge classification...
April 19, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28418684/slow-yogic-breathing-and-long-term-cardiac-autonomic-adaptations-a-pilot-study
#9
Suzanne M Bertisch, Jason Hamner, J Andrew Taylor
OBJECTIVES: To examine whether long-term practice of yogic breathing alters cardiac autonomic control. DESIGN: Age-sex matched, cross-sectional, physiologic pilot study. SETTINGS/LOCATION: Spaulding Rehabilitation Hospital, Cardiovascular Laboratory, Cambridge, MA. PARTICIPANTS: Twenty-six (26) long-term yoga practitioners and 26 age- and sex-matched controls, free of cardiovascular disease. OUTCOME: Cardiac vagal outflow as assessed by respiratory sinus arrhythmia (RSA)...
April 18, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28412983/piezoelectric-technology-in-otolaryngology-and-head-and-neck-surgery-a-review
#10
C Meller, T E Havas
BACKGROUND: Piezoelectric technology has existed for many years as a surgical tool for precise removal of soft tissue and bone. The existing literature regarding its use specifically for otolaryngology, and head and neck surgery was reviewed. METHODS: The databases Medline, the Cochrane Central Register of Controlled Trials, PubMed, Embase and Cambridge Scientific Abstracts were searched. Studies were selected and reviewed based on relevance. RESULTS: Sixty studies were identified and examined for evidence of benefits and disadvantages of piezoelectric surgery and its application in otolaryngology...
April 17, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28411418/quantum-mechanics-models-of-the-methanol-dimer-oh%C3%A2-o-hydrogen-bonds-of-%C3%AE-d-glucose-moieties-from-crystallographic-data
#11
Michael Santiago Cintrón, Glenn P Johnson, Alfred D French
The interaction of two methanol molecules, simplified models of carbohydrates and cellulose, was examined using a variety of quantum mechanics (QM) levels of theory. Energy plots for hydrogen bonding distance (H⋯O) and angle (OH⋯O) were constructed. All but two experimental structures were located in stabilized areas on the vacuum phase energy plots. Each of the 399 models was analyzed with Bader's atoms-in-molecules (AIM) theory, which showed a widespread ability by the dimer models to form OH⋯O hydrogen bonds that have bond paths and Bond Critical Points...
March 19, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28411334/normative-values-for-a-tablet-computer-based-application-to-assess-chromatic-contrast-sensitivity
#12
Lakshmi Bodduluri, Mei Ying Boon, Malcolm Ryan, Stephen J Dain
Tablet computer displays are amenable for the development of vision tests in a portable form. Assessing color vision using an easily accessible and portable test may help in the self-monitoring of vision-related changes in ocular/systemic conditions and assist in the early detection of disease processes. Tablet computer-based games were developed with different levels of gamification as a more portable option to assess chromatic contrast sensitivity. Game 1 was designed as a clinical version with no gaming elements...
April 14, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28410877/chronic-fatigue-syndrome-and-the-immune-system-where-are-we-now
#13
REVIEW
Fane Kojo Fosu Mensah, Amolak Singh Bansal, Brian Ford, Geraldine Cambridge
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterised by multiple symptoms including fatigue, headaches and cognitive impairment, which have a significantly adverse effect on the normal functioning and well-being of the individual. These symptoms are often triggered or worsened following physical or mental exertion. ME/CFS has long been thought of as having a significant immunological component, but reports describing changes in immune function are often inconsistent between study groups...
April 11, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28407142/obinutuzumab-induces-superior-b-cell-cytotoxicity-to-rituximab-in-rheumatoid-arthritis-and-systemic-lupus-erythematosus-patient-samples
#14
Venkat Reddy, Christian Klein, David A Isenberg, Martin J Glennie, Geraldine Cambridge, Mark S Cragg, Maria J Leandro
Objective.: A proportion of RA and SLE patients treated with standard doses of rituximab (RTX) display inefficient B cell deletion and poor clinical responses that can be augmented by delivering higher doses, indicating that standard-dose RTX is a sub-optimal therapy in these patients. This study aimed to investigate whether better responses could be achieved with mechanistically different anti-CD20 mAbs. Methods.: We compared RTX with obinutuzumab (OBZ), a new-generation, glycoengineered type II anti-CD20 mAb, in a series of in vitro assays measuring B cell cytotoxicity in RA and SLE patient samples...
April 11, 2017: Rheumatology
https://www.readbyqxmd.com/read/28406690/the-inversion-part-whole-and-composite-effects-reflect-distinct-perceptual-mechanisms-with-varied-relationships-to-face-recognition
#15
Constantin Rezlescu, Tirta Susilo, Jeremy B Wilmer, Alfonso Caramazza
Face recognition is thought to rely on specific mechanisms underlying a perceptual bias toward processing faces as undecomposable wholes. This face-specific "holistic processing" is commonly quantified using 3 measures: the inversion, part-whole, and composite effects. Consequently, many researchers assume that these 3 effects measure the same cognitive mechanism(s) and these mechanisms contribute to the wide range of individual differences seen in face recognition ability. We test these assumptions in a large sample (N = 282), with individual face recognition abilities measured by the well-validated Cambridge Face Perception Test...
April 13, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28405380/robust-associations-between-the-20-item-prosopagnosia-index-and-the-cambridge-face-memory-test-in-the-general-population
#16
Katie L H Gray, Geoffrey Bird, Richard Cook
Developmental prosopagnosia (DP) is a neurodevelopmental condition, characterized by lifelong face recognition deficits. Leading research groups diagnose the condition using complementary computer-based tasks and self-report measures. In an attempt to standardize the reporting of self-report evidence, we recently developed the 20-item prosopagnosia index (PI20), a short questionnaire measure of prosopagnosic traits suitable for screening adult samples for DP. Strong correlations between scores on the PI20 and performance on the Cambridge Face Memory Test (CFMT) appeared to confirm that individuals possess sufficient insight into their face recognition ability to complete a self-report measure of prosopagnosic traits...
March 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28403642/book-review-extraordinary-science-and-psychiatry-responses-to-the-crisis-in-mental-health-research-extraordinary-science-and-psychiatry-responses-to-the-crisis-in-mental-health-research-poland-j-tekin-s-editors-cambridge-ma-mit-press-2017-327-p-us-50-cloth
#17
https://www.readbyqxmd.com/read/28400696/seprafilm%C3%A2-application-method-in-laparoscopic-surgery
#18
Mun-Kun Hong, Dah-Ching Ding
BACKGROUND AND OBJECTIVES: Postoperative adhesions occur less often in laparoscopies than in laparotomies, but the incidence can be reduced further. Seprafilm, a sodium hyaluronate/carboxymethylcellulose absorbable barrier, was developed to prevent adhesions after abdominal surgery, and is approved for postoperative adhesion prevention. However, Seprafilm is seldom used in laparoscopic surgery because of its tendency to break apart when it is inserted into the abdominal cavity through a trocar, resulting in a high placement failure rate...
January 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28394419/managing-obstetric-emergencies-and-trauma-the-moet-course-manual-revised-3rd-edition-edited-by-sara-paterson-brown-and-charlotte-howell-cambridge-cambridge-university-press-2016-499-pp-index-110-paperback
#19
REVIEW
Aaron Lawrence, Emily McLaren
No abstract text is available yet for this article.
February 15, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28392167/associations-between-a-fetal-imprinted-gene-allele-score-and-late-pregnancy-maternal-glucose-concentrations
#20
C J Petry, K Mooslehner, P Prentice, M G Hayes, M Nodzenski, D M Scholtens, I A Hughes, C L Acerini, K K Ong, W L Lowe, D B Dunger
AIM: We hypothesised that some of the genetic risk for gestational diabetes (GDM) is due to the fetal genome affecting maternal glucose concentrations. Previously, we found associations between fetal IGF2 gene variants and maternal glucose concentrations in late pregnancy. METHODS: In the present study, we tested associations between SNP alleles from 15 fetal imprinted genes and maternal glucose concentrations in late pregnancy in the Cambridge Baby Growth and Wellbeing cohorts (1160 DNA trios)...
April 6, 2017: Diabetes & Metabolism
keyword
keyword
9170
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"