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Dementia-related behaviors

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https://www.readbyqxmd.com/read/29350060/-so-they-are-not-alive-dementia-reality-disjunctions-and-conversational-strategies
#1
Lars-Christer Hydén, Christina Samuelsson
In some conversations involving persons with Alzheimer's disease, the participants may have to deal with the difficulty that they do not share a common ground in terms of not only who is alive or dead, but even more, who could possibly be alive. It is as if the participants face a reality disjunction. There are very few empirical studies of this difficulty in conversations involving persons with Alzheimer's disease or other kinds of dementia diagnoses. Often studies of confabulation have a focus on the behavior and experience of the healthy participants, but rarely on the interaction and the collaborative contributions made by the person with dementia...
January 1, 2018: Dementia
https://www.readbyqxmd.com/read/29336830/interdisciplinary-development-and-implementation-of-a-dementia-skills-training-program-in-a-va-community-living-center-a-pilot-study
#2
Lindsay A Gerolimatos, Kyle S Page, Phyllis Balestracci, Kate L M Hinrichs
This pilot study investigates the usefulness of a dementia care training program developed by an interdisciplinary team to address problem behaviors associated with dementia. Staff members of a VA Community Living Center completed an 8-hour workshop covering fundamental knowledge about dementia and instruction in skills to use with patients through video, lecture, and role-plays. Measures on dementia knowledge and perceived self-efficacy were completed by staff members before and after the workshop. Results revealed increases in self-efficacy and knowledge, with particular gains in general knowledge of dementia and communicating with patients...
January 11, 2018: Geriatric Nursing
https://www.readbyqxmd.com/read/29319813/testing-the-implementation-of-the-veder-contact-method-a-theatre-based-communication-method-in-dementia-care
#3
Petra Boersma, Julia C M van Weert, Birgit I Lissenberg-Witte, Berno van Meijel, Rose-Marie Dröes
Background and Objectives: There is a lack of research on implementation of person-centered care in nursing home care. The purpose of this study was to assess the implementation of the Veder contact method (VCM), a new person-centered method using theatrical, poetic and musical communication for application in 24-hr care. Research Design and Methods: Caregivers (n = 136) and residents (n = 141) participated in a 1-year quasi-experimental study. Foundation Theater Veder implemented VCM on six experimental wards and rated implementation quality...
January 8, 2018: Gerontologist
https://www.readbyqxmd.com/read/29315202/the-effects-of-white-noise-on-agitated-behaviors-mental-status-and-activities-of-daily-living-in-older-adults-with-dementia
#4
Li-Wei Lin, Shu-Chuan Weng, Hua-Shan Wu, Lu-Jen Tsai, Ya-Ling Lin, Shu-Hui Yeh
BACKGROUND: The aging of society is a global trend, and care of older adults with dementia is an urgent challenge. As dementia progresses, patients exhibit negative emotions, memory disorders, sleep disorders, and agitated behavior. Agitated behavior is one of the most difficult problems for family caregivers and healthcare providers to handle when caring for older adults with dementia. PURPOSE: The aim of this study was to investigate the effectiveness of white noise in improving agitated behavior, mental status, and activities of daily living in older adults with dementia...
February 2018: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29314273/psychological-well-being-and-risk-of-dementia
#5
Angelina R Sutin, Yannick Stephan, Antonio Terracciano
OBJECTIVE: Well-being is a psychological resource that buffers against age-related disease. We test whether this protective effect extends to dementia and whether it is independent of distress. METHODS: Participants (N = 10,099) were from the Health and Retirement Study. Five aspects of positive psychological functioning (life satisfaction, optimism, mastery, purpose in life, and positive affect) were tested as predictors of incident dementia over 6 to 8 years...
January 3, 2018: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29304748/revisiting-the-link-between-cognitive-decline-and-masticatory-dysfunction
#6
Chia-Shu Lin
Age-related decline in cognitive functions and dementia are major challenges in geriatric healthcare. Accumulating evidence from clinical, epidemiological and animal research suggests that tooth loss may be a risk factor for the decline of cognitive functions. This issue highlights the role of the brain-stomatognathic axis in geriatric medicine. Whether input from the stomatognathic apparatus can affect the brain remains an open debate. By revisiting the evidence published in the past five years, we argue that the hypothesis regarding the association between cognitive decline and masticatory dysfunction should be carefully interpreted...
January 5, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29299378/moral-processing-deficit-in-behavioral-variant-frontotemporal-dementia-is-associated-with-facial-emotion-recognition-and-brain-changes-in-default-mode-and-salience-network-areas
#7
Jan Van den Stock, Daphne Stam, François-Laurent De Winter, Dante Mantini, Benedikt Szmrecsanyi, Koen Van Laere, Rik Vandenberghe, Mathieu Vandenbulcke
Introduction: Behavioral variant frontotemporal dementia (bvFTD) is associated with abnormal emotion recognition and moral processing. Methods: We assessed emotion detection, discrimination, matching, selection, and categorization as well as judgments of nonmoral, moral impersonal, moral personal low- and high-conflict scenarios. Results: bvFTD patients gave more utilitarian responses on low-conflict personal moral dilemmas. There was a significant correlation between a facial emotion processing measure derived through principal component analysis and utilitarian responses on low-conflict personal scenarios in the bvFTD group (controlling for MMSE-score and syntactic abilities)...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29298278/the-impact-of-air-pollution-to-central-nervous-system-in-children-and-adults
#8
Radim J Sram, Milos Veleminsky, Milos Veleminsky, Jana Stejskalová
The aim of this paper was to review studies analyzing the associations between air pollution and neurodevelopment in children as well as the effect on adult population. Effect of prenatal exposure to polycyclic aromatic hydrocarbons (PAHs, benzo[a]pyrene, B[a]P) were already studied on cohorts from New York, Poland, China, and Spain. All results indicate changes of child behavior and neurodevelopment at the age of 3-9 years, decrease of IQ, increase of Attention Deficit Hyperactivity Disorder (ADHD), decrease of brain-derived neurotrophic factor (BDNF), reduction of left hemisphere white matter...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29278938/moving-through-predeath-grief-psychological-support-for-family-caregivers-of-people-with-dementia
#9
Franziska Meichsner, Stefanie Köhler, Gabriele Wilz
When caring for a family member with dementia, continuous losses and predeath grief can adversely affect the caregivers' physical and mental health. Interventions for caregivers should therefore also aim at coping with loss and managing predeath grief. It was the objective of the present study to describe sources of grief caregivers report during therapy and to investigate how therapists can support caregivers. Two caregivers who participated in a randomized controlled trial were selected for this case study...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29262273/dietary-supplementation-with-allium-hirtifolium-and-or-astragalus-hamosus-improved-%C3%A2-memory-and-reduced-neuro-inflammation-in-the-rat-model-of-alzheimer-s-disease
#10
Zahra Bahaeddin, Asal Yans, Fariba Khodagholi, Shamim Sahranavard
Allium hirtifolium Boiss and Astragalus hamosus L. are mentioned in Iranian traditional medicine ‎documentation as therapy for a kind of dementia with the features and symptoms similar to those ‎of Alzheimer's disease (AD). In the present study, the effects of these herbs on neuro-‎inflammation and memory have been evaluated as new therapies in amyloid beta (Aβ) induced ‎memory impairment model. Separate groups of rats were fed with A. hirtifolium or A. hamosus ‎extract (both 100 mg/kg/day) started one week before stereotaxic surgery to 24 hours before ‎behavioral ‎testing (totally, for 16 successive days)...
December 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29260038/can-suitable-candidates-for-levodopa-carbidopa-intestinal-gel-therapy-be-identified-using-current-evidence
#11
REVIEW
Maria José Catalán, Angelo Antonini, Matilde Calopa, Ovidiu Băjenaru, Oriol de Fábregues, Adolfo Mínguez-Castellanos, Per Odin, José Manuel García-Moreno, Stephen W Pedersen, Zvezdan Pirtošek, Jaime Kulisevsky
Advanced Parkinson's disease (APD) is characterized by increased functional disability, caused by motor complications, the presence of axial symptoms, and emergent disease- and drug-related non-motor symptoms. One of the advanced therapies available is intrajejunal infusion of levodopa/carbidopa intestinal gel (LCIG); however, patient selection for this treatment is sometimes difficult, particularly because of overlapping indications with other alternatives. In recent years, strong evidence has supported the use of LCIG in treating motor fluctuations associated with APD, and several clinical studies provide emerging evidence for additional benefits of LCIG treatment in certain patients...
September 2017: ENeurologicalSci
https://www.readbyqxmd.com/read/29249960/behavioral-and-neuroimaging-evidence-for-facial-emotion-recognition-in-elderly-korean-adults-with-mild-cognitive-impairment-alzheimer-s-disease-and-frontotemporal-dementia
#12
Soowon Park, Taehoon Kim, Seong A Shin, Yu Kyeong Kim, Bo Kyung Sohn, Hyeon-Ju Park, Jung-Hae Youn, Jun-Young Lee
Background: Facial emotion recognition (FER) is impaired in individuals with frontotemporal dementia (FTD) and Alzheimer's disease (AD) when compared to healthy older adults. Since deficits in emotion recognition are closely related to caregiver burden or social interactions, researchers have fundamental interest in FER performance in patients with dementia. Purpose: The purpose of this study was to identify the performance profiles of six facial emotions (i.e., fear, anger, disgust, sadness, surprise, and happiness) and neutral faces measured among Korean healthy control (HCs), and those with mild cognitive impairment (MCI), AD, and FTD...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29246926/combined-active-humoral-and-cellular-immunization-approaches-for-the-treatment-of-synucleinopathies
#13
Edward Rockenstein, Gary Ostroff, Fusun Dikengil, Florentina Rus, Michael Mante, Jazmin Florio, Anthony Adame, Ivy Trinh, Changyoun Kim, Cassia Overk, Eliezer Masliah, Robert A Rissman
Dementia with Lewy bodies (DLB), Parkinson's disease (PD) and Multiple System Atrophy (MSA) are age-related neurodegenerative disorders characterized by progressive accumulation of α-synuclein (α-syn) and jointly termed synucleinopathies. Currently, no disease-modifying treatments are available for these disorders. Previous preclinical studies showed that active and passive immunizations targeting α-syn partially ameliorates behavioral deficits and α-syn accumulation; however, it is unknown if combining humoral and cellular immunization might act synergistically to reduce inflammation and improve microglial-mediated α-syn clearance...
December 15, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29234725/computerized-cognitive-training-for-older-diabetic-adults-at-risk-of-dementia-study-protocol-for-a-randomized-controlled-trial
#14
Rachel Bloom, Michal Schnaider-Beeri, Ramit Ravona-Springer, Anthony Heymann, Hai Dabush, Lior Bar, Shirel Slater, Yuri Rassovsky, Alex Bahar-Fuchs
Introduction: Older adults with type 2 diabetes are at high risk of cognitive decline and dementia and form an important target group for dementia risk reduction studies. Despite evidence that computerized cognitive training (CCT) may benefit cognitive performance in cognitively healthy older adults and those with mild cognitive impairment, whether CCT may benefit cognitive performance or improve disease self-management in older diabetic adults has not been studied to date. In addition, whether adaptive difficulty levels and tailoring of interventions to individuals' cognitive profile are superior to generic training remains to be established...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29233723/the-different-faces-of-the-p-a53t-alpha-synuclein-mutation-a-screening-of-greek-patients-with-parkinsonism-and-or-dementia
#15
Marianthi Breza, Georgios Koutsis, Georgia Karadima, Constantin Potagas, Chrisoula Kartanou, Sokratis G Papageorgiou, George P Paraskevas, Elisabeth Kapaki, Leonidas Stefanis, Marios Panas
BACKGROUND: The p. A53T mutation in the alpha-synuclein (SNCA) gene is a rare cause of autosomal dominant Parkinson's disease (PD). Although generally rare, it is particularly common in the Greek population due to a founder effect. A53T-positive PD patients often develop dementia during disease course and may very rarely present with dementia. METHODS: We screened for the p. A53T SNCA mutation a total of 347 cases of Greek origin with parkinsonism and/or dementia, collected over 15 years at the Neurogenetics Unit, Eginition Hospital, University of Athens...
December 9, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29233097/individualized-support-for-informal-caregivers-of-people-with-dementia-effectiveness-of-the-german-adaptation-of-reach-ii
#16
Martin Berwig, Stephanie Heinrich, Jenny Spahlholz, Nina Hallensleben, Elmar Brähler, Hermann-Josef Gertz
BACKGROUND: Individualized, outreach and structured multicomponent interventions are a promising intervention approach to relieve the burden of informal caregivers of people with dementia. In this study, we adapted and evaluated a multicomponent intervention (Resources for Enhancing Alzheimer's Caregiver Health II, REACH II), which was developed in the USA, to the German health-care system. Therefore the project is called the German adaptation of REACH II (in German: Deutsche Adaptation der REACH II, DE-REACH)...
December 12, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29228107/the-impact-of-antipsychotic-drugs-on-long-term-care-nursing-home-admission-and-death-among-dementia-patients
#17
Michael Nerius, Kristina Johnell, Sara Garcia-Ptacek, Maria Eriksdotter, Britta Haenisch, Gabriele Doblhammer
Background: Behavioral and psychological symptoms of dementia are commonly treated with antipsychotic drugs (APDs), which have been associated with adverse health effects. We examine the effect of APDs on long-term care (LTC), nursing home admission (NH), and death of dementia patients. Methods: We used health claims data of the largest German health insurer from 2004 to 2010 and followed newly-diagnosed dementia patients aged 60 years and older into LTC, NH, and until death...
December 8, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29226876/serum-c-peptide-visfatin-resistin-and-ghrelin-are-altered-in-sporadic-and-grn-associated-frontotemporal-lobar-degeneration
#18
Roberta Zanardini, Luisa Benussi, Silvia Fostinelli, Claudia Saraceno, Miriam Ciani, Barbara Borroni, Alessandro Padovani, Giuliano Binetti, Roberta Ghidoni
Frontotemporal lobar degeneration (FTLD) is a group of complex neurodegenerative disease characterized by progressive deterioration of the frontal and anterior temporal lobes of the brain resulting in different heterogeneous conditions, mainly characterized by personality changes, behavioral disturbances, such as binge eating, and deficits in language and executive functions. Null mutations in progranulin gene (GRN) are one of the most frequent genetic determinants in familial frontotemporal dementia. Recently, progranulin was recognized as an adipokine involved in diet-induced obesity and insulin resistance revealing its metabolic function...
December 1, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29216633/greater-experience-of-negative-non-target-emotions-by-patients-with-neurodegenerative-diseases-is-related-to-lower-emotional-well-being-in-caregivers
#19
Kuan-Hua Chen, Jenna L Wells, Marcela C Otero, Sandy J Lwi, Claudia M Haase, Robert W Levenson
BACKGROUND: Behavioral symptoms in patients with neurodegenerative diseases can be particularly challenging for caregivers. Previously, we reported that patients with frontotemporal dementia (FTD) and Alzheimer's disease (AD) experienced emotions that were atypical or incongruent with a given situation (i.e., non-target emotions). AIM: We tested the hypothesis that greater experience of non-target emotions by patients is associated with lower caregiver emotional well-being...
December 8, 2017: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/29209201/do-lifestyle-activities-protect-against-cognitive-decline-in-aging-a-review
#20
Gregory J Christie, Tara Hamilton, Bradley D Manor, Norman A S Farb, Faranak Farzan, Andrew Sixsmith, Jean-Jacques Temprado, Sylvain Moreno
The number of patients suffering from dementia is expected to more than triple by the year 2040, and this represents a major challenge to publicly-funded healthcare systems throughout the world. One of the most effective prevention mechanisms against dementia lies in increasing brain- and cognitive-reserve capacity, which has been found to reduce the behavioral severity of dementia symptoms as neurological degeneration progresses. To date though, most of the factors known to enhance this reserve stem from largely immutable history factors, such as level of education and occupational attainment...
2017: Frontiers in Aging Neuroscience
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