Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Devangi Shah, Jeffrey M Chambliss, Rory E Nicolaides, Timothy G Chow
No abstract text is available yet for this article.
April 16, 2024: Journal of Allergy and Clinical Immunology in Practice
#2
JOURNAL ARTICLE
Joris A J Osinga, Yindi Liu, Tuija Männistö, Marina Vafeiadi, Fang-Biao Tao, Bijay Vaidya, Tanja G M Vrijkotte, Lorena Mosso, Judit Bassols, Abel López-Bermejo, Laura Boucai, Ashraf Aminorroaya, Ulla Feldt-Rasmussen, Aya Hisada, Jun Yoshinaga, Maarten A C Broeren, Sachiko Itoh, Reiko Kishi, Ghalia Ashoor, Liangmiao Chen, Flora Veltri, Xuemian Lu, Peter N Taylor, Suzanne J Brown, Leda Chatzi, Polina V Popova, Elena N Grineva, Farkhanda Ghafoor, Amna Pirzada, Maryam Kianpour, Emily Oken, Eila Suvanto, Andrew Hattersley, Marisa Rebagliato, Isolina Riaño-Galán, Amaia Irizar, Martine Vrijheid, Juana Maria Delgado-Saborit, Ana Fernández-Somoano, Loreto Santa-Marina, Kristien Boelaert, Gabriela Brenta, Rima Dhillon-Smith, Chrysoula Dosiou, Jennifer L Eaton, Haixia Guan, Sun Y Lee, Spyridoula Maraka, Lilah F Morris-Wiseman, Caroline T Nguyen, Zhongyan Shan, Mònica Guxens, Victor J M Pop, John P Walsh, Kypros H Nicolaides, Mary E D'Alton, W Edward Visser, David M Carty, Christian Delles, Scott M Nelson, Erik K Alexander, Layal Chaker, Glenn E Palomaki, Robin P Peeters, Sofie Bliddal, Kun Huang, Kris G Poppe, Elizabeth N Pearce, Arash Derakhshan, Tim I M Korevaar
Background: International guidelines recommend targeted screening to identify gestational thyroid dysfunction. However, currently used risk factors have questionable discriminative ability. We quantified the risk for thyroid function test abnormalities for a subset of risk factors currently used in international guidelines. Methods: We included prospective cohort studies with data on gestational maternal thyroid function and potential risk factors (maternal age, body mass index [BMI], parity, smoking status, pregnancy through in vitro fertilization, twin pregnancy, gestational age, maternal education, and thyroid peroxidase antibody [TPOAb] or thyroglobulin antibody [TgAb] positivity)...
March 28, 2024: Thyroid: Official Journal of the American Thyroid Association
#3
JOURNAL ARTICLE
Juan Enrique Berner, Marios Nicolaides, Stephen Ali, Georgios Pafitanis, Jane Preece, Sally Hopewell, Jagdeep Nanchahal
OBJECTIVES: To evaluate the efficacy of pharmacological interventions for treating early-stage, pain predominant, adhesive capsulitis, also known as frozen shoulder. METHODS: We performed a systematic review in accordance with PRSIMA guidelines. Searches were conducted on PUBMED, EMBASE and Cochrane Central Register of Controlled Trials on the 24th of February 2022. Outcomes were shoulder pain, shoulder function and range of movement. Synthesis involved both qualitative analysis for all studies and pairwise meta-analyses followed by a network meta-analysis for randomised controlled trials (RCTs)...
March 27, 2024: Rheumatology
#4
JOURNAL ARTICLE
Tünde Montgomery-Csobán, Kimberley Kavanagh, Paul Murray, Chris Robertson, Sarah J E Barry, U Vivian Ukah, Beth A Payne, Kypros H Nicolaides, Argyro Syngelaki, Olivia Ionescu, Ranjit Akolekar, Jennifer A Hutcheon, Laura A Magee, Peter von Dadelszen
BACKGROUND: Affecting 2-4% of pregnancies, pre-eclampsia is a leading cause of maternal death and morbidity worldwide. Using routinely available data, we aimed to develop and validate a novel machine learning-based and clinical setting-responsive time-of-disease model to rule out and rule in adverse maternal outcomes in women presenting with pre-eclampsia. METHODS: We used health system, demographic, and clinical data from the day of first assessment with pre-eclampsia to predict a Delphi-derived composite outcome of maternal mortality or severe morbidity within 2 days...
April 2024: The Lancet. Digital health
#5
REVIEW
Marija Dimitrievska, Dravie Bansal, Marta Vitale, John Strouboulis, Annarita Miccio, Kypros H Nicolaides, Sara El Hoss, Panicos Shangaris, Joanna Jacków-Malinowska
Recent advancements in gene editing illuminate new potential therapeutic approaches for Sickle Cell Disease (SCD), a debilitating monogenic disorder caused by a point mutation in the β-globin gene. Despite the availability of several FDA-approved medications for symptomatic relief, allogeneic hematopoietic stem cell transplantation (HSCT) remains the sole curative option, underscoring a persistent need for novel treatments. This review delves into the growing field of gene editing, particularly the extensive research focused on curing haemoglobinopathies like SCD...
March 7, 2024: Blood Reviews
#6
JOURNAL ARTICLE
M Charakida, E Gibbone, I Huluta, A Syngelaki, A Wright, K H Nicolaides
BACKGROUND: First, a logistic regression model, based on maternal demographic characteristics and medical history and blood pressure at 11-13 weeks' gestation, can identify about 70% of women who develop future chronic hypertension (CH) in the three years following pregnancy, at screen positive rate of 10%. Second, at mid-gestation women who subsequently develop hypertensive disorders of pregnancy (HDP) have increased peripheral vascular resistance and mild cardiac functional and morphological alterations and these cardiovascular abnormalities persist for at least 2 years after delivery...
March 13, 2024: Ultrasound in Obstetrics & Gynecology
#7
JOURNAL ARTICLE
Gino Cioffi, Kristin A Waite, Mantas Dmukauskas, Michael Glantz, Sonikpreet Aulakh, Theodore Nicolaides, Soma Sengupta, Joanne Xiu, Jill S Barnholtz-Sloan
No abstract text is available yet for this article.
2024: Neuro-oncology advances
#8
JOURNAL ARTICLE
Divya Ramakrishnan, Sarah C Brüningk, Marc von Reppert, Fatima Memon, Nazanin Maleki, Sanjay Aneja, Anahita Fathi Kazerooni, Ali Nabavizadeh, MingDe Lin, Khaled Bousabarah, Annette Molinaro, Theodore Nicolaides, Michael Prados, Sabine Mueller, Mariam S Aboian
BACKGROUND AND PURPOSE: Response on imaging is widely used to evaluate treatment efficacy in clinical trials of pediatric gliomas. While conventional criteria rely on 2D measurements, volumetric analysis may provide a more comprehensive response assessment. There is sparse research on the role of volumetrics in pediatric gliomas. Our purpose was to compare 2D and volumetric analysis with the assessment of neuroradiologists using the Brain Tumor Reporting and Data System (BT-RADS) in BRAF V600E-mutant pediatric gliomas...
March 7, 2024: AJNR. American Journal of Neuroradiology
#9
JOURNAL ARTICLE
S Dimopoulou, D Neculcea, I Papastefanou, A Galan, K H Nicolaides, M Charakida
BACKGROUND: Women with hypertensive disorders of pregnancy (HDP) are at increased risk of developing hypertension and cardiovascular disease later in life. However, from studies so far, it is difficult to define whether this association reflects preexisting maternal cardiovascular risk or merely reflect a potentially causal relationship between HDP and later cardiovascular risk. OBJECTIVES: We performed detailed cardiovascular assessment in women at mid-gestation, prior to development of a HDP and at 2 years post-partum aiming to identify cardiovascular changes prior to development of HDP and to assess persistent cardiovascular alterations long after the HDP event...
March 4, 2024: Ultrasound in Obstetrics & Gynecology
#10
JOURNAL ARTICLE
S Dimopoulou, D Neculcea, I Papastefanou, A Galan, M Androulaki, K H Nicolaides, M Charakida
OBJECTIVE: Epidemiological studies suggest that children following in utero exposure to hypertensive disorders of pregnancy (HDP) may be at increased long term cardiovascular risk. However, data in early childhood are lacking. We aimed to investigate the independent influence of HDP on childhood heart after accounting for differences in childhood risk factor profile. METHODS: We performed detailed cardiovascular assessment in fetuses at mid-gestation and at a median of 2...
March 4, 2024: Ultrasound in Obstetrics & Gynecology
#11
JOURNAL ARTICLE
Andrew N Nicolaides, Jawed Fareed, Alex C Spyropoulos, Rt Horn Lord Kakkar, Pier L Antignani, Efthymios Avgerinos, Niels Baekgaard, Emma Barber, Ruth L Bush, Joseph A Caprini, Daniel L Clarke-Pearson, Patrick VAN Dreden, Ismail Elalami, Grigoris Gerotziafas, Harry Gibbs, Samuel Goldhaber, Stavros Kakkos, Elmira Lefkou, Nicos Labropoulos, Renato D Lopes, Armando Mansilha, Chryssa Papageorgiou, Paolo Prandoni, Eduardo Ramacciotti, Carla Rognoni, Tomasz Urbanek, Jeanine M Walenga
No abstract text is available yet for this article.
February 2024: International Angiology: a Journal of the International Union of Angiology
#12
JOURNAL ARTICLE
C Y L Poon, T Y Leung, C C Wang, S Daljit, K Nicolaides, F Scaglia, K Y Y Cheng, A Milosavljevic
No abstract text is available yet for this article.
February 2024: Hong Kong Medical Journal
#13
JOURNAL ARTICLE
D Cuenca-Gómez, C De Paco Matallana, V Rolle, M Mendoza, N Valiño, R Revello, B Adiego, M C Casanova, F S Molina, J L Delgado, A Wright, F Figueras, K H Nicolaides, B Santacruz, M M Gil
OBJECTIVE: To compare the predictive performance for pre-eclampsia (PE) of three different first-trimester mathematical models of screening, which combine maternal risk factors with mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI) and serum placental growth factor (PlGF), and two risk scoring systems, based on NICE and ACOG recommendations. METHODS: This was a prospective cohort study performed in eight fetal-medicine units in five different regions of Spain between September 2017 and December 2019...
February 27, 2024: Ultrasound in Obstetrics & Gynecology
#14
JOURNAL ARTICLE
Demetris Demetriou, Pavlos Mavromatidis, Michael F Petrou, Demetris Nicolaides
This study presents the Construction and Demolition Waste Object Detection Dataset (CODD), a benchmark dataset specifically curated for the training of object detection models and the full-scale implementation of automated sorting of Construction and Demolition Waste (CDW). The CODD encompasses a comprehensive range of CDW scenarios, capturing a diverse array of debris and waste materials frequently encountered in real-world construction and demolition sites. A noteworthy feature of the presented study is the ongoing collaborative nature of the dataset, which invites contributions from the scientific community, ensuring its perpetual improvement and adaptability to emerging research and practical requirements...
February 19, 2024: Waste Management
#15
JOURNAL ARTICLE
I Papastefanou, A Szczepkowska, M Tezhaeva, M De Pauli, M Charakida, K H Nicolaides
OBJECTIVE: To investigate whether placental function, reflected in the levels of angiogenic factors, is associated with maternal cardiac function and hemodynamic responses at 19 to 24 weeks' gestation after adjustment for maternal risk factors and pregnancy complications. METHODS: Prospective study on women with singleton pregnancies attending Kings' College Hospital, London, UK for a routine hospital visit at 19-24 weeks' gestation. We recorded maternal characteristics and measured mean arterial pressure, maternal heart rate, serum placental growth factor and soluble fms-like tyrosine kinase 1 (sFLT-1)...
February 14, 2024: Ultrasound in Obstetrics & Gynecology
#16
JOURNAL ARTICLE
Michail Sideris, Kathrine S Rallis, Marios Nicolaides, Ashvin Kuri, Nadine Schottler, Nathalie Paulus, Orthmar Haas, Romuald Krajewski, Joao Grenho, Vassilios Papalois
BACKGROUND: The authors systematically appraise a large database of continuous professional development (CPD) and continuous medical education (CME) events against the European Accreditation Council for Continuous Medical Education (EACCME) framework. METHODS: The authors performed a retrospective observational study of all CPD or CME events within the European Union of Medical Specialists (UEMS) database between 2017 and 2019, including 91 countries and 6034 events...
February 2024: Annals of Medicine and Surgery
#17
JOURNAL ARTICLE
Stephanie G Nicolaides, Theodorus H C Mostert, Trevor McIntyre
Latrine sites are used as areas for the deposition of scent-containing excretions and play important roles in intraspecific olfactory communication, territoriality, sexual attraction, and defense behaviors of many mammals. African clawless otters ( Aonyx capensis ) likely use latrine sites as primary areas for scent marking and scent communication but no studies to date have investigated their potential role or site selection. We assessed latrine site selection at 2 spatial scales (micro- and macroscale) and recorded behaviors via camera trap recordings...
February 2024: Journal of Mammalogy
#18
JOURNAL ARTICLE
David Wright, Alan Wright, Laura A Magee, Peter Von Dadelszen, Kypros H Nicolaides
OBJECTIVE: To investigate the validity of the conclusion from Cochrane reviews and meta-analyses that treatment with calcium supplementation during pregnancy reduces the risk for pre-eclampsia by 55%, which has been influential in international guidelines and future research. DESIGN: Sensitivity analysis of data from Cochrane reviews of trials evaluating high-dose calcium supplementation (of at least 1 g/day) for reduction of pre-eclampsia risk. SETTING: Systematic review and meta-analysis...
February 1, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
#19
JOURNAL ARTICLE
First trimester risk of preeclampsia and rate of spontaneous birth in patients without preeclampsia.
Paolo I Cavoretto, Antonio Farina, Noemi Salmeri, Argyro Syngelaki, Min Yi Tan, Kypros H Nicolaides
BACKGROUND: First-trimester screening for preeclampsia (PE), by a combination of maternal risk factors and mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI) and placental growth factor (PlGF), as proposed by the Fetal Medicine Foundation (FMF) provides effective prediction of preterm PE. Placental dysfunction is a potential precursor of spontaneous birth. OBJECTIVE: The objective of this study is to examine whether the estimated risk of PE is associated with the gestational age at onset of spontaneous delivery in the absence of PE...
January 18, 2024: American Journal of Obstetrics and Gynecology
#20
JOURNAL ARTICLE
Marietta Charakida, Alan Wright, Laura A Magee, Argyro Syngelaki, Peter von Dadelszen, Ranjit Akolekar, David Wright, Kypros H Nicolaides
BACKGROUND: Cardiovascular disease is the leading cause of mortality in women. Pregnancy is an ideal period to implement cardiovascular prevention strategies as women seek medical help. We aimed to develop a predictive model to identify women at increased risk for chronic hypertension (CH) based on information collected in the index pregnancy. METHODS: Cohort of 26 511 women seen in 2 consecutive pregnancies. Included were women without CH, with information on maternal characteristics and blood pressure at 11 to 13 weeks' gestation, and the development of preeclampsia or gestational hypertension (GH) in the index pregnancy...
February 2024: Hypertension
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
