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https://www.readbyqxmd.com/read/29048520/pain-acceptance-as-a-predictor-of-medical-utilization-and-school-absenteeism-in-adolescents-with-chronic-pain
#1
Michelle A Clementi, Grace S Kao, Evelyn Monico
Objective: Identifying factors contributing to high medical utilization and productivity loss is important, given the high cost of pediatric chronic pain. The current study examined chronic pain acceptance as a predictor of medical utilization and school absenteeism in adolescents with chronic pain. Methods: In all, 122 adolescents (aged 12-21 years) with chronic pain and their parents/guardians completed questionnaires assessing medical visits (past 6 months), medication usage, and number of school absences (past month)...
October 12, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28994642/reasons-for-not-treating-women-with-postmenopausal-osteoporosis-with-prescription-medications-physicians-and-patients-perspectives
#2
Jessica Papadopoulos Weaver, Kelly Olsson, Ravi Sadasivan, Ankita Modi, Shuvayu Sen
BACKGROUND: In the United States, between one-third and two thirds of postmenopausal women do not begin treatment with a prescription osteoporosis medication after a diagnosis of osteoporosis. The objective of this study was to understand the reasons for this lack of treatment. MATERIALS AND METHODS: Online physician and patient surveys were administered in 2013. The physician survey included a chart review of untreated postmenopausal women recently diagnosed with osteoporosis and gathered data on physicians' practices regarding the management of osteoporosis in postmenopausal women...
October 10, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28994329/the-value-of-self-medication-summary-of-existing-evidence
#3
Joshua Noone, Christopher M Blanchette
AIM: The aim of this review was to identify the international evidence that is currently available on the economic value of self-care through responsible self-medication, in terms of the measures related to access to treatment, time, and productivity. METHODS: A targeted literature search was conducted for 1990-2016, including data gathered from members of the World Self-Medication Industry and searches on PubMed, EBSCOHost, and Google Scholar. Specific searches of individual drug classes known to be switched to non-prescription status in this period were also conducted...
November 3, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28987598/the-brazilian-market-of-herbal-medicinal-products-and-the-impacts-of-the-new-legislation-on-traditional-medicines
#4
Ana Cecília Bezerra Carvalho, Túlio Nader Lana, João Paulo Silvério Perfeito, Dâmaris Silveira
ETHNOPHARMACOLOGICAL RELEVANCE: the herbal medicinal products (HMP) market is expanding in the world, an expansion that has not occurred in Brazil when considering the number of licensed products. Despite being a megadiverse country, the number of HMP licensed in Brazil is small, and the number of HMP obtained from native species is even smaller. A new legislation for herbal products licensing, which divides the products into two categories, Herbal Medicine (HM) and Traditional Herbal Product (THP) was launched in Brazil focusing on traditional use, as well as a law regulating the use of biodiversity and traditional knowledge...
October 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28967696/single-dose-pharmacokinetic-study-of-diphenhydramine-hcl-in-children-and-adolescents
#5
Cathy K Gelotte, Brenda A Zimmerman, Gary A Thompson
Diphenhydramine pharmacokinetics were characterized following a single oral dose in children aged 2 to 17 years using a weight- and age-based dosing schedule with more tiers than the current age-based dosing schedule recommended by the nonprescription drug monograph. This study was conducted in 42 subjects, aged 2 to 17 years. Doses were based on a weight-age dosing schedule, ranging from 6.25 to 50 mg. An oral dose was administered with water about 2 hours after a light breakfast. Plasma samples were obtained up to 48 hours after dosing and analyzed for diphenhydramine...
October 2, 2017: Clinical Pharmacology in Drug Development
https://www.readbyqxmd.com/read/28951854/ospemifene-a-novel-option-for-the-treatment-of-vulvovaginal-atrophy
#6
REVIEW
Jae Jun Shin, Seul Ki Kim, Jung Ryeol Lee, Chang Suk Suh
Ospemifene-a third-generation selective estrogen receptor modulator approved by the Food and Drug Administration in 2013-is an oral medication for the treatment of dyspareunia. In postmenopausal women with vulvovaginal atrophy, ospemifene significantly improves the structure and pH levels of the vagina, reducing dyspareunia. It is available as a 60-mg tablet; hence, women who may have had prior difficulty with vaginal administration or on-demand use of nonprescription lubricants and moisturizers would likely prefer this form of treatment...
August 2017: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/28951675/the-extent-of-use-of-online-pharmacies-in-saudi-arabia
#7
Norah Abanmy
PURPOSE: Online pharmacies sell medicine over the Internet and deliver them by mail. The main objective of this study is to explore the extent of use of online pharmacies in Saudi Arabia which will be useful for the scientific community and regulators. METHODS: An Arabic survey questionnaire was developed for this study. The questionnaire was distributed via email and social media. Four sections were created to cover the objectives: experience with online shopping in general, demographics, awareness of the existence and customer experiences of buying medicine online, and reasons for buying/not buying medicine online...
September 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28947415/prescribing-of-electronic-activity-monitors-in-cardiometabolic-diseases-qualitative-interview-based-study
#8
Alice Bellicha, Sandrine Macé, Jean-Michel Oppert
BACKGROUND: The prevalence of noncommunicable diseases, including those such as type 2 diabetes, obesity, dyslipidemia, and hypertension, so-called cardiometabolic diseases, is high and is increasing worldwide. Strong evidence supports the role of physical activity in management of these diseases. There is general consensus that mHealth technology, including electronic activity monitors, can potentially increase physical activity in patients, but their use in clinical settings remains limited...
September 23, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28891368/medication-management-in-schools-2015-survey-results
#9
Erin D Maughan, Ann Marie McCarthy, Maria Hein, Yelena Perkhounkova, Michael W Kelly
The increasing prevalence of chronic conditions in children, for both common and rare conditions, over the past 30 years, and the increase in the number and range of medications used to manage these conditions, has contributed to the need to address medication management in schools. The purpose of this article is to present the key findings from a national survey on medication administration in schools. A nonexperimental cross-sectional design was used in this descriptive study. An online survey was sent to school nurses across the country...
January 1, 2017: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/28807658/self-reported-participation-in-voluntary-nonprescription-syringe-sales-in-california-s-central-valley
#10
Robin A Pollini
OBJECTIVES: California Senate Bill 41 (SB41), effective January 2012, is a human immunodeficiency virus/hepatitis C virus prevention measure designed to expand syringe access among injection drug users (IDUs) by allowing pharmacies to sell syringes without a prescription. This study assesses self-reported implementation of SB41 and characterizes barriers amenable to intervention. DESIGN: Interviewer-administered survey. SETTING AND PARTICIPANTS: Fresno and Kern Counties, CA...
November 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28780741/channeling-in-the-use-of-nonprescription-paracetamol-and-ibuprofen-in-an-electronic-medical-records-database-evidence-and-implications
#11
Rachel B Weinstein, Patrick Ryan, Jesse A Berlin, Amy Matcho, Martijn Schuemie, Joel Swerdel, Kayur Patel, Daniel Fife
INTRODUCTION: Over-the-counter analgesics such as paracetamol and ibuprofen are among the most widely used, and having a good understanding of their safety profile is important to public health. Prior observational studies estimating the risks associated with paracetamol use acknowledge the inherent limitations of these studies. One threat to the validity of observational studies is channeling bias, i.e. the notion that patients are systematically exposed to one drug or the other, based on current and past comorbidities, in a manner that affects estimated relative risk...
August 5, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28712737/pharmacists-can-help-prevent-lipoid-pneumonia
#12
Ann E Cabri, Afoma King, Lee Morrow, Mark A Malesker
OBJECTIVES: To report 2 cases of lipoid pneumonia. SUMMARY: Lipoid pneumonia is an inflammatory process in the lower airways due to the presence of lipid molecules in the alveoli. Exogenous lipoid pneumonia is due to the inhalation or aspiration of fat-containing substances. Historically, mineral oil is the most common medication cause but there have also been several reports of lipoid pneumonia associated with petroleum jelly, medicated vapor rub, and lip glosses...
July 14, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28616436/initiatives-to-reduce-nonprescription-sales-and-dispensing-of-antibiotics-findings-and-implications
#13
Vanda Marković-Peković, Nataša Grubiša, Johanita Burger, Ljubica Bojanić, Brian Godman
OBJECTIVE: Irrational use of antimicrobials is a major driver of antimicrobial resistance, exacerbated by dispensing antibiotics without a prescription. Our previous study suggested this was a problem in the Republic of Srpska despite legislation. Since then, a number of activities have been initiated. Consequently, the study aimed to ascertain whether these multiple initiatives had reduced this. METHODS: Patients visiting all community pharmacies in the Republic from October 2014 to July 2015 presenting with symptoms typical of an acute, viral, and mostly uncomplicated upper respiratory tract infection, with results compared to the previous study...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28571654/is-nutrient-content-and-other-label-information-for-prescription-prenatal-supplements-different-from-nonprescription-products
#14
COMPARATIVE STUDY
Leila G Saldanha, Johanna T Dwyer, Karen W Andrews, LaVerne L Brown, Rebecca B Costello, Abby G Ershow, Pavel A Gusev, Constance J Hardy, Pamela R Pehrsson
BACKGROUND: Prenatal supplements are often recommended to pregnant women to help meet their nutrient needs. Many products are available, making it difficult to choose a suitable supplement because little is known about their labeling and contents to evaluate their appropriateness. OBJECTIVE: To determine differences between prescription and nonprescription prenatal supplements available in the United States regarding declared nutrient and nonnutrient ingredients and the presence of dosing and safety-related information...
September 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28527884/adjuvant-medications-that-improve-survival-after-locoregional-therapy
#15
F Edward Boas, Etay Ziv, Hooman Yarmohammadi, Karen T Brown, Joseph P Erinjeri, Constantinos T Sofocleous, James J Harding, Stephen B Solomon
PURPOSE: To determine if outpatient medications taken at the time of liver tumor embolization or ablation affect survival. MATERIALS AND METHODS: A retrospective review was done of 2,032 liver tumor embolization, radioembolization, and ablation procedures performed in 1,092 patients from June 2009 to April 2016. Pathology, hepatocellular carcinoma (HCC) stage (American Joint Committee on Cancer), neuroendocrine tumor (NET) grade, initial locoregional therapy, overall survival after initial locoregional therapy, Child-Pugh score, Eastern Cooperative Oncology Group performance status, Charlson Comorbidity Index, and outpatient medications taken at the time of locoregional therapy were analyzed for each patient...
July 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28506439/clinical-review-loperamide-toxicity
#16
REVIEW
Peter E Wu, David N Juurlink
Loperamide is a nonprescription opioid widely used for the treatment of diarrhea. Although it is relatively safe at therapeutic doses, increasing reports describe its misuse and abuse at very high doses either for euphoric effects or to attenuate symptoms of opioid withdrawal. Life-threatening loperamide toxicity can result from the relatively new clinical syndrome of loperamide-induced cardiac toxicity. These patients are often young and may present in cardiac arrest or with unheralded, recurrent syncope in conjunction with ECG abnormalities, including marked QT-interval prolongation, QRS-interval widening, and ventricular dysrhythmias...
August 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28506365/drug-induced-liver-injury-the-hepatic-pathologist-s-approach
#17
REVIEW
David E Kleiner
The evaluation of liver biopsies in suspected drug-induced liver injury (DILI) can be complex. The biopsy may be approached systematically, by identification of histologic lesions and then identification of the overall pattern of injury. Potential DILI must be separated from concomitant non-DILI liver disease. The findings can be analyzed with respect to the various prescription and nonprescription medications and dietary supplements under suspicion to provide a complete interpretation of the findings. The pathologic findings, the histologic differential diagnosis, and expert interpretation are part of a complete biopsy assessment and provide information that is of greatest value in patient management...
June 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/28483828/sources-of-sodium-in-us-adults-from-3-geographic-regions
#18
Lisa J Harnack, Mary E Cogswell, James M Shikany, Christopher D Gardner, Cathleen Gillespie, Catherine M Loria, Xia Zhou, Keming Yuan, Lyn M Steffen
BACKGROUND: Most US adults consume excess sodium. Knowledge about the dietary sources of sodium intake is critical to the development of effective reduction strategies. METHODS: A total of 450 adults were recruited from 3 geographic locations: Birmingham, AL (n=150); Palo Alto, CA (n=150); and the Minneapolis-St. Paul, MN (n=150), metropolitan areas. Equal numbers of women and men from each of 4 race/ethnic groups (blacks, Asians, Hispanics, and non-Hispanic whites) were targeted for recruitment...
May 9, 2017: Circulation
https://www.readbyqxmd.com/read/28483007/dangers-of-nonprescription-medicines-educating-and-counseling-older-adults
#19
REVIEW
Joshua Davis Kinsey, Diane Nykamp
OBJECTIVE: To provide a review for health care providers regarding appropriate education and counseling for older adults involving commonly used nonprescription medicines with potential for adverse effects, drug-drug interactions, or toxicity when incorrectly selected or overused. DATA SOURCES: A literature search was performed using MEDLINE and PUBMED to locate relevant articles. DAILYMED was used for manufacturer dosage recommendations. Additionally, peer-reviewed textbooks were consulted for evidence-based standards of care...
May 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28481965/polypharmacy-as-a-risk-factor-for-clinically-relevant-sarcopenia-results-from-the-berlin-aging-study-ii
#20
Maximilian König, Dominik Spira, Ilja Demuth, Elisabeth Steinhagen-Thiessen, Kristina Norman
Background: Sarcopenia affects more than 10% of older adults. Next to age-associated physiologic changes, diseases like diabetes or inflammatory, neurological, malignant and endocrine disorders may contribute to the development of sarcopenia. Likewise, polypharmacy, i.e., multiple drug use, is common among older adults. Although the two conditions frequently co-occur, the association of polypharmacy with sarcopenia has not yet been examined. We investigated the association of polypharmacy and sarcopenia in a large cohort of community-dwelling older adults (60-84 years)...
May 6, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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