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Weight loss in the elderly

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https://www.readbyqxmd.com/read/29658677/acute-complications-following-endoscopic-intragastric-balloon-insertion-for-treatment-of-morbid-obesity-in-elderly-patients-a-single-center-experience
#1
Nunzio Velotti, Paolo Bianco, Alessio Bocchetti, Marco Milone, Domenico Manzolillo, Paola Maietta, Maurizio Amato, Oreste Buonomo, Giuseppe Petrella, Mario Musella
BACKGROUND: Obesity is a serious disease, with an increasing incidence also among subjects over 60 years old; surgical management has proven to be the most effective in the production of significant and durable weight loss. Intragastric balloon (IGB) treatment, promotes a reduction of five to nine body mass index (BMI) units in 6 months with an impressive improvement of obesity-associated comorbidities. METHODS: Two hundred and twenty five patients, 106 men (47...
April 13, 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/29628040/-patterns-of-brain-ageing
#2
Carlos Fernández Viadero, Rosario Verduga Vélez, Dámaso Crespo Santiago
Neuroplasticity lends the brain a strong ability to adapt to changes in the environment that occur during ageing. Animal models have shown alterations in neurotransmission and imbalances in the expression of neural growth factor. Changes at the morphometric level are not constant. Volume loss is related to alterations in neuroplasticity and involvement of the cerebral neuropil. Although there are no conclusive data, physical exercise improves the molecular, biological, functional and behavioural-cognitive changes associated with brain ageing...
June 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29598904/lipopolysaccharide-induces-subacute-cerebral-microhemorrhages-with-involvement-of-nitric-oxide-synthase-in-rats
#3
Jing Zeng, Hóngyi Zhào, Zhixin Liu, Weiwei Zhang, Yonghua Huang
BACKGROUND: Cerebral microhemorrhage (CMH) is a neuropathological term that could be easily found in cerebral amyloid angiopathy, intracerebral hemorrhages, etc. CMHs could be detected clearly in vivo by magnetic resonance imaging (MRI)-susceptibility-weighted imaging or MRI T2* scan. This terminology is now accepted in the area of neuroimaging. CMHs are quite common in elderly patients and are associated with several other neuropsychiatric disorders. The causes of CMHs are complicated, and neuroinflammation is considered as one of the well-accepted mechanical factors...
March 26, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29590725/nutritional-issues-and-nutrition-support-in-older-home-care-patients-in-the-city-of-zagreb
#4
Darija Vranešić Bender, Marta Kovačević, Miro Hanževački, Božena Vrabec, Vanesa Benković, Viktor Domislović, Željko Krznarić
Population aging is a global demographic trend showing continuous growth and among its consequences is a rise in malnutrition that is characteristic for the elderly. The objective of this study was to evaluate nutritional status of elderly home care patients immediately after hospital discharge and to determine factors that affect nutritional status using questionnaires based on validated tools (NRS-2002, DETERMINE checklist) and basic medical history data. The study involved 76 elderly individuals (51.3% of them older than 70) living in the City of Zagreb...
December 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29588023/managing-soft-tissues-in-severe-lower-limb-trauma-in-an-ageing-population
#5
Timothy M Noblet, Philippa C Jackson, Patrick Foster, David Martin Taylor, Paul J Harwood, Jay D Wiper
PURPOSE: With an ageing population, the incidence of trauma in those aged over 65 years is increasing. Strategies for dealing with these patients must be developed. At present the standard management of open tibial fractures in the UK is described by the BOAST4 guidelines (from the British Orthopaedic Association and British Association of Plastic & Aesthetic Surgeons). It is not clear to what extent these are appropriate for older patients. We describe our experience of managing elderly patients presenting with open tibial fractures...
March 13, 2018: Injury
https://www.readbyqxmd.com/read/29582895/-feeling-more-self-confident-cheerful-and-safe-experiences-from-a-health-promoting-intervention-in-community-dwelling-older-adults-a-qualitative-study
#6
Å von Berens, A Koochek, M Nydahl, R A Fielding, T Gustafsson, D R Kirn, T Cederholm, M Södergren
OBJECTIVES: Studies show that regular exercise in combination with nutritional support can be effective in managing sarcopenia, which is age-related involuntary loss of skeletal muscle mass and strength. Qualitative investigations of participants' experiences from interventions in this domain are scarce. In this study, we explored older persons' experiences from an intervention designed to prevent sarcopenia, with the aim of capturing the participants' thoughts and opinions. DESIGN: A qualitative study embedded in the multicenter randomized clinical trial The Vitality and Vigor in the Elderly study, VIVE2...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29573418/short-and-long-term-outcomes-of-oropharyngeal-cancer-care-in-the-elderly
#7
Kevin Motz, Robert J Herbert, Carole Fakhry, Harry Quon, Hyunseok Kang, Ana P Kiess, David W Eisele, Wayne M Koch, Kevin D Frick, Christine G Gourin
OBJECTIVE: To examine associations between pretreatment variables, short-term and long-term swallowing and airway impairment, and survival in elderly patients (age > 65 years) treated for oropharyngeal squamous cell cancer (SCCA). STUDY DESIGN: Retrospective analysis of Surveillance, Epidemiology, and End Results (SEER)-Medicare data. METHODS: Longitudinal data from 666 patients diagnosed with oropharyngeal SCCA from 2004 to 2007 were evaluated using cross-tabulations, multivariate logistic regression, and survival analysis...
March 24, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29564306/sarcopenic-obesity-in-elderly-korean-women-a-nationwide-cross-sectional-study
#8
Young Nam Kwon, Sung Sang Yoon, Kyung-Hag Lee
Background: Sarcopenia causes loss of muscle mass in the elderly and is associated with development of metabolic syndrome in those with obesity. This study evaluated the prevalence of sarcopenic obesity (SO) in healthy Korean elderly women. Methods: This study was based on data from the Korea National Health and Nutrition Examination Survey IV and V, 2008-2011. Whole body dual energy X-ray absorptiometry and body mass index measurement were performed for all patients...
February 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29542279/megestrol-acetate-for-cachexia-anorexia-syndrome-a-systematic-review
#9
REVIEW
Vicente Ruiz-García, Eduardo López-Briz, Rafael Carbonell-Sanchis, Sylvia Bort-Martí, José Luis Gonzálvez-Perales
In 1993, megestrol acetate (MA) was approved by the US Food and Drug Administration for the treatment of anorexia, cachexia, or unexplained weight loss in patients with acquired immunodeficiency syndrome. The mechanism by which MA increases appetite is unknown, and its effectiveness for anorexia and cachexia in neoplastic, elderly, and acquired immunodeficiency syndrome patients is under investigation. This is an updated version of a Cochrane systematic review first published in 2005 and later updated in 2013 entitled 'Megestrol acetate for the treatment of anorexia-cachexia syndrome'...
March 14, 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29530547/selenium-intake-and-metabolic-syndrome-a-systematic-review
#10
REVIEW
Anabelle Retondario, Ricardo Fernandes, Gabriele Rockenbach, Mariane de Almeida Alves, Liliana Paula Bricarello, Erasmo Benicio Santos de Moraes Trindade, Francisco de Assis Guedes de Vasconcelos
BACKGROUND & AIMS: Metabolic syndrome is a multi-causal disease. Its treatment includes lifestyle changes with a focus on weight loss. This systematic review assessed the association between Selenium intake and metabolic syndrome. METHODS: Data were collected mainly from four databases: PubMed, CENTRAL (Cochrane), Scopus and Web of Knowledge. Keywords related to metabolic syndrome, selenium, as well as metabolic syndrome features were searched. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement...
March 2, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29528748/fragility-fractures-in-the-upper-limb-proximal-and-distal-humerus
#11
Shyam Kumar, Ulhas Sonar, Iqbal Singh
The incidence of fragility fractures of the humerus is increasing worldwide. Although clinicians are aware of fractures of hips and wrists, fractures of the shoulder and elbow do not receive much attention. A considerable proportion of the elderly population (estimated at 10-24%) is dependent on walking aids. A well-functioning and pain-free shoulder and elbow is essential for use of these aids. The impact of loss of mobility in the elderly is well known, hence the overall impact of these fractures on the individual can be considerable...
March 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29525937/bariatric-surgery-in-the-elderly-is-associated-with-similar-surgical-risks-and-significant-long-term-health-benefits
#12
Uri Kaplan, Scott Penner, Forough Farrokhyar, Nicole Andruszkiewicz, Ruth Breau, Scott Gmora, Dennis Hong, Mehran Anvari
PURPOSE: Older age (> 60) has been considered a relative contraindication for bariatric surgery due to increased complication risk. This study examined the risks and benefits of bariatric surgery for patients older than 60 years in Canadian population. METHODS: This was a retrospective cohort study of the Ontario Bariatric Registry: a database recording peri-operative and post-operative outcomes of publicly funded bariatric surgeries across the province. Patients who completed 1 year follow-up, who underwent laparoscopic gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG) between January 2010 and May 2013, were divided into older (> 60) and younger (> 60) cohorts, and outcomes were compared...
March 10, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29519962/-prevention-of-dementia-with-special-reference-to-lifestyle-and-vascular-risk-factors
#13
Haruo Hanyu
There is a wide range of potentially modifiable risk factors for Alzheimer's disease and dementia, including cardiovascular risk factors (e.g. hypertension, diabetes, dyslipidemia, obesity, sleep-apnea syndrome), psychosocial factors (e.g., depression), health behaviors (e.g., low level of physical or mental activity, smoking status), and head trauma. In the elderly, weight loss associated with frailty and sarcopenia is another risk factor for dementia. Recent epidemiological studies have shown that the prevalence of dementia has declined in the US and European countries during the last 20 years...
March 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29519234/relationship-of-aging-skeletal-muscle-mass-and-tooth-loss-with-masseter-muscle-thickness
#14
Kohei Yamaguchi, Haruka Tohara, Koji Hara, Ayako Nakane, Eriko Kajisa, Kanako Yoshimi, Shunsuke Minakuchi
BACKGROUND: Previous studies have reported a relationship between masseter muscle thickness and tooth loss or limb muscle thickness. However, it is not yet known whether masseter muscle thickness is related to appendicular skeletal muscle mass, and grip strength. The purpose of this study was to determine which of the two variables-tooth loss or appendicular skeletal muscle mass index-is more strongly related to masseter muscle thickness, and to identify a suitable indicator of decreasing masseter muscle thickness in healthy elderly individuals...
March 8, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29504447/the-impacts-of-weight-change-and-weight-change-intention-on-health-related-quality-of-life-in-the-korean-elderly
#15
Eun Sun So
OBJECTIVE: This study aimed to identify the impacts of weight change and weight change intention on health-related quality of life (HRQL) among community-dwelling Korean elderly individuals. METHOD: Data on those aged 75 years and above from the Korean National Health and Nutrition Examination Survey were analyzed using multiple regression analysis. RESULTS: Compared with no weight change, unintentional weight loss was associated with significantly lower adjusted overall HRQL and lower scores in the subdimensions of mobility, pain/discomfort, usual activities, and self-care (in order), whereas intentional weight loss was associated with significantly poorer scores for anxiety/depression...
March 1, 2018: Journal of Aging and Health
https://www.readbyqxmd.com/read/29474746/a-systematic-review-of-the-evidence-and-analysis-of-the-consequences
#16
REVIEW
J-Matthias Löhr, Nikola Panic, Miroslav Vujasinovic, Caroline S Verbeke
Senior people constitute the fastest growing segment of the population. The elderly are at risk for malnutrition, thought to be caused by reduced food intake or involution of the physiological capacity of the GI tract. Age-related changes are well known in other secretory organs such as liver, kidney, and intestine. The pancreas, representing a metabolically active organ with uptake and breakdown of essential nutritional components, changes its morphology and function with age. During childhood, the volume of the pancreas increases, reaching a plateau between 20-60 years, and declines thereafter...
February 23, 2018: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29465537/laparoscopic-gastrectomy-for-elderly-patients-with-gastric-cancer-a-systematic-review-with-meta-analysis
#17
Yu Pan, Ke Chen, Wei-Hua Yu, Hendi Maher, Sui-Han Wang, Hang-Fen Zhao, Xue-Yong Zheng
BACKGROUND: Laparoscopic gastrectomy (LG) has been widely applied in patients with gastric cancer (GC). However, the safety and application value of LG in elderly patients with GC was still unclear. In this study, we aimed to evaluate the feasibility and safety of LG for elderly patients with GC using the meta-analysis. METHODS: Studies comparing elderly patients and nonelderly patients who underwent LG for GC were reviewed and collected from the PubMed, EBSCO, Cochrane Library, and EMBASE...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29453728/single-site-port-robotic-assisted-hysterectomy-an-update
#18
REVIEW
Christos Iavazzo, Evelyn Eleni Minis, Ioannis D Gkegkes
Single-incision approach in robotic gynecology is a relatively new concept. The role of single-port systems in robotic hysterectomy, their advantages and disadvantages, as well as the technical challenges, are still under investigation. A systematic review was performed by searching in PubMed and Scopus databases. In 810 out of 1225 patients, hysterectomy was performed for non-neoplastic disease. Single-Site ® was the most common port system. Duration of the procedure and relative blood loss ranged from 60 to 311 min and 7 to 750 ml, respectively...
February 16, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29449943/aging-like-physiological-changes-in-the-skin-of-japanese-obese-diabetic-patients
#19
Ai Ibuki, Shoko Kuriyama, Yukiko Toyosaki, Misaki Aiba, Moeko Hidaka, Yoshiko Horie, Chihiro Fujimoto, Fumiyuki Isami, Eriko Shibata, Yasuo Terauchi, Tomoko Akase
Objective: Obesity-associated diabetes causes aging-like changes to skin physiology in animal models, but there have been no clinical studies focusing on human obese diabetic patients. The purpose of this study was to examine the hypothesis that obesity-associated diabetes accelerates aging-like skin changes in Japanese people. Methods: This cross-sectional study enrolled obese-diabetes patients (body mass index ≥ 25 kg m-2) and healthy volunteers (body mass index < 25 kg m -2 ) as controls...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29438496/the-adiponectin-paradox-in-the-elderly-associations-with-body-composition-physical-functioning-and-mortality
#20
Joshua F Baker, Anne B Newman, Alka Kanaya, Mary B Leonard, Babette Zemel, Iva Miljkovic, Jin Long, David Weber, Tamara B Harris
Background: To determine if adiponectin levels are associated with weight loss, low muscle mass, and physical functioning among the elderly and to determine independent associations with incident disability and death. Methods: Included were 3,044 participants from the Health, Aging and Body Composition Study who had whole-body dual energy absorptiometry performed to evaluate appendicular lean mass index (ALMI, kg/m2) and fat mass index (FMI, kg/m2), CT measures of thigh muscle density, weight histories, estimates of physical functioning, and adiponectin levels at enrollment...
February 9, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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