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Weight loss in the elderly

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https://www.readbyqxmd.com/read/28077154/incremental-decreases-in-quality-adjusted-life-years-qaly-associated-with-higher-levels-of-depressive-symptoms-for-u-s-adults-aged-65-years-and-older
#1
Haomiao Jia, Erica I Lubetkin
BACKGROUND: Quality-adjusted life years (QALY) is a single value index that quantifies the overall burden of disease. It reflects all aspects of heath, including nonfatal illness and mortality outcomes by weighting life-years lived with health-related quality of life (HRQOL) scores. This study examine the burden of disease due to increasing levels of depressive symptoms by examining the association between the 9-item Patient Health Questionnaire (PHQ-9) scores and QALY for U.S. adults aged 65 years and older...
January 11, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28070457/the-concurrent-validity-and-reliability-of-the-leg-motion-system-for-measuring-ankle-dorsiflexion-range-of-motion-in-older-adults
#2
Carlos Romero Morales, César Calvo Lobo, David Rodríguez Sanz, Irene Sanz Corbalán, Beatriz Ruiz Ruiz, Daniel López López
BACKGROUND: New reliable devices for range of motion (ROM) measures in older adults are necessary to improve knowledge about the functional capability in this population. Dorsiflexion ROM limitation is associated with ankle injuries, foot pain, lower limb disorders, loss of balance, gait control disorders and fall risk in older adults. The aim of the present study was to assess the validity and reliability of the Leg Motion device for measuring ankle dorsiflexion ROM in older adults. METHODS: Adescriptive repeated-measures study was designed to test the reliability of Leg Motion in thirty-three healthy elderly patients older than 65 years...
2017: PeerJ
https://www.readbyqxmd.com/read/28065474/a-single-low-dose-of-a-cgmp-recombinant-bcg-vaccine-elicits-protective-t-cell-immunity-against-the-human-respiratory-syncytial-virus-infection-and-prevents-lung-pathology-in-mice
#3
Pablo F Céspedes, Emma Rey-Jurado, Janyra A Espinoza, Claudia A Rivera, Gisela Canedo-Marroquín, Susan M Bueno, Alexis M Kalergis
Human respiratory syncytial virus (hRSV) is a major health burden worldwide, causing the majority of hospitalizations in children under two years old due to bronchiolitis and pneumonia. HRSV causes year-to-year outbreaks of disease, which also affects the elderly and immunocompromised adults. Furthermore, both hRSV morbidity and epidemics are explained by a consistently high rate of re-infections that take place throughout the patient life. Although significant efforts have been invested worldwide, currently there are no licensed vaccines to prevent hRSV infection...
January 5, 2017: Vaccine
https://www.readbyqxmd.com/read/28031949/the-effect-of-frailty-should-be-considered-in-the-management-plan-of-older-people-with-type-2-diabetes
#4
REVIEW
Ahmed H Abdelhafiz, Luan Koay, Alan J Sinclair
The prevalence of diabetes is increasing especially in older age due to increased life expectancy. In old age, diabetes is associated with high comorbidity burden and increased prevalence of geriatric syndromes including frailty in addition to micro- and macro-vascular complications. The emergence of frailty may change the natural history of Type 2 diabetes from a progressive to a regressive course with increased risk of hypoglycemia. This may result in normalization of blood glucose levels and lead to a state of burnt-out diabetes in frail older people with significant weight loss...
March 2016: Future Science OA
https://www.readbyqxmd.com/read/28025528/elevated-plasma-vitamin-b12-concentrations-are-independent-predictors-of-in-hospital-mortality-in-adult-patients-at-nutritional-risk
#5
Silvia Cappello, Emanuele Cereda, Mariangela Rondanelli, Catherine Klersy, Barbara Cameletti, Riccardo Albertini, Daniela Magno, Marilisa Caraccia, Annalisa Turri, Riccardo Caccialanza
Background: Elevated plasma vitamin B12 concentrations were identified as predictors of mortality in patients with oncologic, hepatic and renal diseases, and in elderly and critically ill medical patients. The association between vitamin B12 concentrations and in-hospital mortality in adult patients at nutritional risk has not been assessed. Methods: In this five-year prospective study, we investigated whether high vitamin B12 concentrations (>1000 pg/mL) are associated with in-hospital mortality in 1373 not-bed-ridden adult patients at nutritional risk (Nutrition Risk Index <97...
December 23, 2016: Nutrients
https://www.readbyqxmd.com/read/27999852/effect-of-a-high-protein-energy-restricted-diet-combined-with-resistance-training-on-metabolic-profile-in-older-individuals-with-metabolic-impairments
#6
T Amamou, E Normandin, J Pouliot, I J Dionne, M Brochu, E Riesco
Adequate protein intake and resistance training are effective strategies to maintain muscle mass, but the effect of their combination on metabolic profile during weight loss remains to be determined in older adults. The main objective of this study was to determine the effect of a 16-week high-protein caloric restriction combined with resistance training on chronic disease risk factors in obese older individuals with metabolic impairments. A total of 26 overweight adults aged between 60 and 75 years (BMI 32...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27994350/an-elderly-male-with-tingly-legs-and-a-heavy-heart-persisting-with-the-diagnosis
#7
Mudassar Kharadi, Sreenath Vedula Harsha, Gayathri Gopalakrishnan, G A Karthick, Vimal Raj, Subramanian Kannan
Pursuing a diagnosis despite a negative nerve biopsy report requires a strong clinical conviction. Paying attention to clinical details and a diligent review of medical records is needed to solve cases in which the diagnosis is not obvious despite numerous tests. We present once such case of an elderly man with chronic diarrhea, weight loss, and peripheral neuropathy and elaborate on a step by step basis on how the clinical thought process evolved after sifting through the reports of scan and tests done during his work up...
October 2016: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/27896893/an-acute-disseminated-encephalomyelitis-like-illness-in-the-elderly-neuroimaging-and-neuropathology-findings
#8
Ulrike W Kaunzner, Elliott Salamon, Elena Pentsova, Marc Rosenblum, Sasan Karimi, Nancy Nealon, Ehud Lavi, Dara G Jamieson
INTRODUCTION: Acute disseminated encephalomyelitis (ADEM) is a rare demyelinating disease of the central nervous system (CNS) that classically occurs in children and adolescents. It characteristically presents with acute inflammation, resulting in demyelination, often following an infectious disease. ADEM has been described in adult patients, but the incidence in the adult and especially elderly population is low. CASES: We describe five older adults (age 57 to 85) who presented with acute neurological symptoms...
November 29, 2016: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/27895390/maslinic-acid-in-olive-fruit-alleviates-mild-knee-joint-pain-and-improves-quality-of-life-by-promoting-weight-loss-in-the-elderly
#9
Satoshi Fukumitsu, Myra O Villareal, Kazuhiko Aida, Akihiro Hino, Noriya Hori, Hiroko Isoda, Yuji Naito
Consumption of olives (Olea europaea L.) is associated with a low incidence of inflammation-related diseases. Olive fruit is rich in bioactive pentacyclic triterpenoids, mainly maslinic acid. This study, a randomized, double-blind, and placebo-controlled trial, examined the effects of an orally administered maslinic acid supplement, olive fruit extract, on 20 middle-aged and elderly volunteers with mild knee joint pain. Each subject (58 ± 7 years) received either olive fruit extract, containing 50 mg maslinic acid (n = 12), or placebo (n = 8) daily for 12 weeks and evaluated for pain and physical functions as primary outcome measures...
November 2016: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/27890894/clinical-complete-response-from-chemotherapy-in-an-elderly-patient-with-metastatic-gastric-cancer-a-case-report
#10
Tetsuro Kawagoe, Yuta Maruki, Hiroyuki Nagoya, Yuki Kosugi, Teppei Akimoto, Hiroshi Yamawaki, Yasuhiro Kodaka, Mayumi Shimpuku, Nobue Ueki, Seiji Futagami, Kazumasa Miyake, Katsuhiko Iwakiri
An 81-year-old man was admitted with upper abdominal pain and weight loss. Esophagogastroduodenoscopy revealed a large tumor located from the gastric angle to the body. Histological analysis of a biopsy revealed a moderately differentiated adenocarcinoma. Computed tomography revealed metastases in the liver and lung and the patient was subsequently diagnosed with metastatic advanced gastric cancer. He was treated with chemotherapy using S-1 (80 mg/m(2)) and cisplatin (CDDP) (60 mg/m(2)). Twenty-two months after chemotherapy, the gastric tumor, and the nodules in the liver and lung, had disappeared...
2016: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/27885226/association-between-the-nutritional-status-and-the-severity-of-sarcopenia-among-community-dwelling-elderly-japanese-people
#11
Satsuki Komai, Yutaka Watanabe, Yoshinori Fujiwara, Hunkyung Kim, Ayako Edahiro, Hisashi Kawai, Hideyo Yoshida, Shuichi Obuchi, Yayoi Tanaka, Hirohiko Hirano
AIM: To investigate the association between nutritional evaluation indices (body mass index, albumin, and weight loss) and sarcopenia severity among community-dwelling elderly people in Japan. METHODS: The subjects consisted of 758 community-dwelling elderly people ≥65 years of age, categorized into two groups by based on Operation of long life medical care system (medical care system for elderly in the latter stage of life), the cut-off value for age used was 75...
2016: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/27872739/30-years-retrospective-review-of-tuberculosis-cases-in-a-tuberculosis-dispensary-in-bursa-nilufer-turkey-1985-2014-changes-of-epidemics
#12
Kayıhan Pala, Harika Gerçek, Tuncay Aydin Taş, Rukiye Çakir, Sedef Özgüç, Timur Yildiz
OBJECTIVE: The aim of this study is to describe the epidemiological and clinical aspects of patients who applied to the Bursa Nilufer Tuberculosis Dispensary by investigating the trends in epidemics over three decades. METHOD: In this retrospective observational study, the records of all tuberculosis cases (1630 patients) treated in the last 30 years (1985-2014) at the Bursa Nilufer Tuberculosis Dispensary were examined and statistically analyzed. RESULTS: Males comprised 65...
2016: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/27847264/dietary-patterns-and-12-year-risk-of-frailty-results-from-the-three-city-bordeaux-study
#13
Sophie Pilleron, Soufiane Ajana, Marthe-Aline Jutand, Catherine Helmer, Jean-François Dartigues, Cécilia Samieri, Catherine Féart
OBJECTIVE: To analyze the association between dietary patterns and the 12-year risk of frailty and its components in community-dwelling elderly French adults. DESIGN: A prospective cohort study. SETTING: The Bordeaux sample of the Three-City Study. PARTICIPANTS: A total of 972 initially nonfrail nondemented participants (336 men and 636 women) aged 73 years on average, re-examined at least once over 12 years. MEASUREMENTS: Five sex-specific dietary clusters were previously derived at baseline...
November 12, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27843074/testosterone-threshold-for-increased-cardiovascular-risk-in-middle-aged-and-elderly-men-a-locally-weighted-regression-analysis
#14
Pin-Wen Liao, Chia-Chang Wu, Kuan-Chou Chen, Fu-Shan Jaw, Hong-Jeng Yu, Shih-Ping Liu, Chen-Hsun Ho
INTRODUCTION: Although testosterone deficiency has a well-known association with increased risk of cardiovascular disease (CVD), the threshold remains to be determined. AIM: To investigate whether there is a discriminatory testosterone level below which the CVD risk increases. METHODS: The study included 876 men 45 to 74 years old who underwent a general health checkup. The Framingham Risk Score was used to estimate the 10-year CVD risk; a high-sensitivity C-reactive protein (hsCRP) level of at least 1 mg/L was considered an indicator of increased CVD risk...
December 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27828581/-phenotype-of-frailty-the-influence-of-each-item-in-determining-frailty-in-community-dwelling-elderly-the-fibra-study
#15
Silvia Lanziotti Azevedo da Silva, Anita Liberalesso Neri, Eduardo Ferrioli, Roberto Alves Lourenço, Rosângela Corrêa Dias
The phenotype of frailty is used to assess frailty among the elderly by examining the following items: weight loss; exhaustion; low level of physical activity; weakness; and slow gait speed. The aim of the study was to evaluate the contribution of each item to determine the frailty syndrome among elderly Brazilians. The analysis was done using Multinomial Logistic Regression. The total sample of 5532 randomly selected elderly people in many cities in Brazil between December 2008 and September 2009 was assessed using the phenotype of frailty...
November 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27828570/self-perceived-health-in-institutionalized-elderly
#16
Javier Jerez-Roig, Dyego Leandro Bezerra Souza, Fabienne Louise Juvêncio Paes de Andrade, Bartolomeu Fagundes de Lima, Rafaela Jordânia de Medeiros, Nayara Priscila Dantas de Oliveira, Sadote Macêdo Cabral, Kenio Costa Lima
This study aimed to verify health self-perception, its prevalence and associated factors in institutionalized elderly. A cross-sectional study is presented herein, conducted in 10 Long-Term care Institutions for the Elderly (LTIE) in the city of Natal (Northeast Brazil), between October and December 2013. Sociodemographic variables were analyzed, along with institution-related and health state variables. Descriptive and bivariate analyses were carried out (Chi-squared test, Fisher's exact test or linear trend Chi-squared test), as well as multivariate analysis (logistic regression)...
November 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27825838/the-relationship-between-oral-health-and-oral-health-related-quality-of-life-among-elderly-people-in-united-kingdom
#17
Mohd Masood, Tim Newton, Noor Nazahiah Bakri, Taimur Khalid, Yaghma Masood
OBJECTIVES: To identify the determinants of OHRQoL among older people in the United Kingdom. METHODS: A subset of elderly (≥65year) participants from the UK Adult Dental Health Survey 2009 data was used. OHRQoL was assessed by means of the OHIP-14 additive score. The number of missing teeth; presence of active caries, dental pain, root caries, tooth wear, periodontal pockets>4mm, loss of attachment>9mm; having PUFA>0 (presence of severely decayed teeth with visible pulpal involvement, ulceration caused by dislocated tooth fragments, fistula and abscess); and wearing a denture were used as predictor variables...
January 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/27810620/mapping-the-factors-affecting-the-frequency-and-types-of-micronuclei-in-an-elderly-population-from-southern-bohemia
#18
Andrea Rossnerova, Katerina Honkova, Jitka Pavlikova, Zuzana Freitinger Skalicka, Renata Havrankova, Ivo Solansky, Pavel Rossner, Radim J Sram, Friedo Zölzer
The micronucleus assay is one of the most common methods used to assess chromosomal damage (losses or breaks) in human peripheral blood lymphocytes (PBL) in genetic toxicology. Most studies have focused on analyzing total micronuclei (MN), but identifying the content of MN can provide more detailed information. The main aim of this study was to map the factors affecting the frequency and types of micronuclei in binucleated cells (BNC) in elderly population. Fluorescence in situ hybridization using Human Pan Centromeric Chromosome Paint was used to identify centromere positive (CEN+) or centromere negative (CEN-) MN...
November 2016: Mutation Research
https://www.readbyqxmd.com/read/27804273/baseline-gray-and-white-matter-volume-predict-successful-weight-loss-in-the-elderly
#19
Fatemeh Mokhtari, Brielle M Paolini, Jonathan H Burdette, Anthony P Marsh, W Jack Rejeski, Paul J Laurienti
OBJECTIVE: The purpose of this study was to investigate whether structural brain phenotypes could be used to predict weight loss success following behavioral interventions in older adults with overweight or obesity and cardiometabolic dysfunction. METHODS: A support vector machine with a repeated random subsampling validation approach was used to classify participants into the upper and lower halves of the weight loss distribution following 18 months of a weight loss intervention...
December 2016: Obesity
https://www.readbyqxmd.com/read/27804083/chronic-rhinosinusitis-with-nasal-polyps-is-associated-with-chronic-otitis-media-in-the-elderly
#20
Seung-No Hong, Woo Hyun Lee, Seung Hoon Lee, Chae-Seo Rhee, Chul Hee Lee, Jeong-Whun Kim
Chronic rhinosinusitis (CRS) and chronic otitis media (COM) are common diseases in the otorhinolaryngology field. Although clinicians frequently encounter patients presenting both diseases simultaneously, a few studies have shown relationships between them. We examined whether CRS was associated with COM in adults who participated in the Korea National Health and Nutrition Examination Survey from 2009 to 2012. A total of 27,492 participants were examined in this cross-sectional epidemiological study. Regression analyses was performed and adjusted for socio-demographics, general health behavior, and other comorbidities...
November 1, 2016: European Archives of Oto-rhino-laryngology
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