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https://www.readbyqxmd.com/read/27931078/advanced-refractory-heart-failure-conservative-or-interventional-approach
#1
Fabio Rigamonti, Fabrizio Montecucco, Luca Liberale
The 2017 ESCI Award for the Best Clinical Research Article goes to the study by Christopher Adlbrecht and co-workers, entitled "Outcome of conservative management vs. assist device implantation in patients with advanced refractory heart failure" [1]. This article was selected among seven finalist articles of outstanding quality and scientific impact [2-7]. This article is protected by copyright. All rights reserved.
December 8, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27930810/alamandine-abrogates-neutrophil-degranulation-in-atherosclerotic-mice
#2
Analina R Da Silva, Sébastien Lenglet, Federico Carbone, Fabienne Burger, Aline Roth, Luca Liberale, Aldo Bonaventura, Franco Dallegri, Nikolaos Stergiopulos, Robson A S Santos, François Mach, Rodrigo A Fraga-Silva, Fabrizio Montecucco
Neutrophil-mediated inflammation was recently identified as an active contributor to athero-progression. Therapeutic strategies inhibiting neutrophil degranulation or recruitment were hypothesized to positively impact on plaque vulnerability. In this study, we investigated whether treatment with the recently discovered agonist of the Mas-related G-coupled receptor type D (MrgD) alamandine would impact on neutrophil degranulation in vivo and in vitro MATERIALS AND METHODS: Fifteen-week old ApoE-/- mice were fed with a Western-type diet for an additional 11 weeks...
December 8, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27929443/enabling-sdn-in-vanets-what-is-the-impact-on-security
#3
Antonio Di Maio, Maria Rita Palattella, Ridha Soua, Luca Lamorte, Xavier Vilajosana, Jesus Alonso-Zarate, Thomas Engel
The demand for safe and secure journeys over roads and highways has been growing at a tremendous pace over recent decades. At the same time, the smart city paradigm has emerged to improve citizens' quality of life by developing the smart mobility concept. Vehicular Ad hoc NETworks (VANETs) are widely recognized to be instrumental in realizing such concept, by enabling appealing safety and infotainment services. Such networks come with their own set of challenges, which range from managing high node mobility to securing data and user privacy...
December 6, 2016: Sensors
https://www.readbyqxmd.com/read/27923944/membrane-oxygenator-use-with-biventricular-assist-device-facilitation-of-support-and-lung-recovery
#4
Kristen Nelson-McMillan, William J Ravekes, William R Thompson, Kristen M Brown, Larry Wolff, Rajeev S Wadia, LeAnn M McNamara, Donald H Shaffner, Ivor D Berkowitz, Marshall L Jacobs, Luca A Vricella
We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support...
December 6, 2016: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/27917111/scale-invariant-disordered-nanotopography-promotes-hippocampal-neuron-development-and-maturation-with-involvement-of-mechanotransductive-pathways
#5
Carsten Schulte, Maddalena Ripamonti, Elisa Maffioli, Martino A Cappelluti, Simona Nonnis, Luca Puricelli, Jacopo Lamanna, Claudio Piazzoni, Alessandro Podestà, Cristina Lenardi, Gabriella Tedeschi, Antonio Malgaroli, Paolo Milani
The identification of biomaterials which promote neuronal maturation up to the generation of integrated neural circuits is fundamental for modern neuroscience. The development of neural circuits arises from complex maturative processes regulated by poorly understood signaling events, often guided by the extracellular matrix (ECM). Here we report that nanostructured zirconia surfaces, produced by supersonic cluster beam deposition of zirconia nanoparticles and characterized by ECM-like nanotopographical features, can direct the maturation of neural networks...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27913339/a-parametric-study-for-the-design-of-an-optimized-ultrasonic-percussive-planetary-drill-tool
#6
Xuan Li, Patrick Harkness, Kevin Worrall, Ryan Timoney, Margaret Lucas
Traditional rotary drilling for planetary rock sampling, in-situ analysis and sample return, is challenging because the axial force and holding torque requirements are not necessarily compatible with lightweight spacecraft architectures in low-gravity environments. This article seeks to optimize an ultrasonic-percussive drill tool to achieve rock penetration with lower reacted force requirements, with a strategic view towards building an Ultrasonic Planetary Core Drill (UPCD) device. The UPCD is a descendant of the Ultrasonic/Sonic Driller/Corer (USDC) technique...
November 29, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27910889/direct-imaging-of-defect-formation-in-strained-organic-flexible-electronics-by-scanning-kelvin-probe-microscopy
#7
Tobias Cramer, Lorenzo Travaglini, Stefano Lai, Luca Patruno, Stefano de Miranda, Annalisa Bonfiglio, Piero Cosseddu, Beatrice Fraboni
The development of new materials and devices for flexible electronics depends crucially on the understanding of how strain affects electronic material properties at the nano-scale. Scanning Kelvin-Probe Microscopy (SKPM) is a unique technique for nanoelectronic investigations as it combines non-invasive measurement of surface topography and surface electrical potential. Here we show that SKPM in non-contact mode is feasible on deformed flexible samples and allows to identify strain induced electronic defects...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27906382/laser-patterned-functionalized-cvd-graphene-as-highly-transparent-conductive-electrodes-for-polymer-solar-cells
#8
Luca La Notte, Enrica Villari, Alessandro Lorenzo Palma, Alberto Sacchetti, Maria Michela Giangregorio, Giovanni Bruno, Aldo Di Carlo, Giuseppe Valerio Bianco, Andrea Reale
A five-layer (5L) graphene on a glass substrate has been demonstrated as a transparent conductive electrode to replace indium tin oxide (ITO) in organic photovoltaic devices. The required low sheet resistance, while maintaining high transparency, and the need of a wettable surface are the main issues. To overcome these, two strategies have been applied: (i) the p-doping of the multilayer graphene, thus reaching 25 Ω □(-1) or (ii) the O2-plasma oxidation of the last layer of the 5L graphene that results in a contact angle of 58° and a sheet resistance of 134 Ω □(-1)...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27898500/patterns-and-trends-of-transcatheter-aortic-valve-implantation-in-italy-insights-from-rispeva
#9
Arturo Giordano, Nicola Corcione, Giuseppe Biondi-Zoccai, Sergio Berti, Anna Sonia Petronio, Carlo Pierli, Patrizia Presbitero, Pietro Giudice, Gennaro Sardella, Antonio L Bartorelli, Roberto Bonmassari, Ciro Indolfi, Alfredo Marchese, Elvis Brscic, Alberto Cremonesi, Luca Testa, Nedy Brambilla, Francesco Bedogni
AIMS: Clinical trials have shown that transcatheter aortic valve implantation for aortic stenosis compares favorably to surgical replacement in high-risk patients and is superior to medical therapy in those at prohibitive risk. There is uncertainty however on patterns and trends in transcatheter aortic valve implantation, especially focusing on Italy. METHODS: The RISPEVA study is a prospective Italian registry including 21 institutions. Patients have been enrolled since late 2012, and data collection includes several baseline, procedural, in-hospital, and follow-up details...
November 24, 2016: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/27890798/performance-of-the-subcutaneous-implantable-defibrillator-in-primary-prevention-patients-with-and-without-reduced-ejection-fraction-versus-secondary-prevention-patients
#10
Lucas Boersma, Craig S Barr, Martin C Burke, Angel R Leon, Dominic A Theuns, John M Herre, Raul Weiss, Mark S Kremers, Petr Neuzil, Michael P Husby, Nathan Carter, Timothy M Stivland, Michael R Gold
BACKGROUND: The subcutaneous implantable defibrillator (S-ICD) provides an alternative to the transvenous ICD (TV-ICD) for prevention of sudden cardiac death (SCD), but has not been well studied in the most commonly treated TV-ICD patient population, namely primary prevention (PP) patients with left ventricular (LV) dysfunction. OBJECTIVE: These analyses were designed to compare clinical outcomes for PP patients with and without a reduced ejection fraction (EF) and secondary prevention (SP) patients implanted with the S-ICD...
November 24, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27877116/are-supramodality-and-cross-modal-plasticity-the-yin-and-yang-of-brain-development-from-blindness-to-rehabilitation
#11
Luca Cecchetti, Ron Kupers, Maurice Ptito, Pietro Pietrini, Emiliano Ricciardi
Research in blind individuals has primarily focused for a long time on the brain plastic reorganization that occurs in early visual areas. Only more recently, scientists have developed innovative strategies to understand to what extent vision is truly a mandatory prerequisite for the brain's fine morphological architecture to develop and function. As a whole, the studies conducted to date in sighted and congenitally blind individuals have provided ample evidence that several "visual" cortical areas develop independently from visual experience and do process information content regardless of the sensory modality through which a particular stimulus is conveyed: a property named supramodality...
2016: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/27874841/using-the-theory-of-planned-behavior-to-explore-hospital-based-nurses-intention-to-use-peripherally-inserted-central-catheter-picc-a-survey-study
#12
Laura Bertani, Maria Carone, Luca Caricati, Serena Demaria, Silvia Fantuzzi, Alessandro Guarasci, Luca Pirazzoli
BACKGROUND AND AIM OF THE WORK: The peripherally inserted central catheters (PICC) have become an alternative to the traditional CVC. PICCs are usually inserted by trained nurses who decided to attend and complete a special training on PICC insertion and management. The present work aimed to investigate the intention of using PICC in a sample of hospital-based nurses using the theory of planned behavior as theoretical framework. METHODS: A cross-sectional design was used in which a questionnaire was delivered to 199 nurses...
November 22, 2016: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/27873145/use-of-refrigerant-spray-of-a-propane-butane-isobutane-gas-mixture-in-the-management-of-keratocystic-odontogenic-tumors-a-preliminary-study
#13
Eduardo Luis de Souza Cruz, Ana Karla da Silva Tabosa, Aline Semblano Carreira Falcão, Talita Tartari, Lucas Machado de Menezes, Edmar Tavares da Costa, José Thiers Carneiro Júnior
PURPOSE: Keratocystic odontogenic tumor (KCOT) is an aggressive benign tumor and the management by complete enucleation followed by cryotherapy maintains the inorganic bone matrix, resulting in better repair and reduces the rates of recurrence. A refrigerant spray with a propane/butane/isobutane gas mixture has been pointed to as an alternative to liquid nitrogen, because the device is easy to handle and contain within the cavity, providing better control and lower risk of injury to the adjacent soft tissue...
November 21, 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27871588/novel-resuscitation-devices-facilitate-complete-neurologic-recovery-after-prolonged-cardiac-arrest-in-postanesthesia-care-unit
#14
Elif C Cingi, Luke A McMahon, Richard C Prielipp
Cardiac arrest in the perioperative period is associated with significant morbidity and mortality. Novel resuscitation devices may afford patients improved survival and limit neurologic injury. We report a case of cardiac arrest in the postanesthesia care unit that required an extensive period of cardiopulmonary resuscitation assisted by the ResQPOD impedance threshold device to optimize coronary perfusion and a LUCAS chest compression system to maintain optimal cardiopulmonary resuscitation while transporting the patient to the cardiac catheterization laboratory...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27869822/current-induced-switching-in-a-magnetic-insulator
#15
Can Onur Avci, Andy Quindeau, Chi-Feng Pai, Maxwell Mann, Lucas Caretta, Astera S Tang, Mehmet C Onbasli, Caroline A Ross, Geoffrey S D Beach
The spin Hall effect in heavy metals converts charge current into pure spin current, which can be injected into an adjacent ferromagnet to exert a torque. This spin-orbit torque (SOT) has been widely used to manipulate the magnetization in metallic ferromagnets. In the case of magnetic insulators (MIs), although charge currents cannot flow, spin currents can propagate, but current-induced control of the magnetization in a MI has so far remained elusive. Here we demonstrate spin-current-induced switching of a perpendicularly magnetized thulium iron garnet film driven by charge current in a Pt overlayer...
November 21, 2016: Nature Materials
https://www.readbyqxmd.com/read/27858238/instrumentation-failure-following-pedicle-subtraction-osteotomy-the-role-of-rod-material-diameter-and-multi-rod-constructs
#16
Andrea Luca, Claudia Ottardi, Maurizio Sasso, Liliana Prosdocimo, Luigi La Barbera, Marco Brayda-Bruno, Fabio Galbusera, Tomaso Villa
PURPOSE: Pedicle subtraction osteotomy (PSO) has a complication rate noticeably higher than other corrective surgical techniques used for the treatment of spinal sagittal imbalance. In particular, rod breakage and pseudoarthrosis remain burning issues of this technique. Goal of this study was to investigate the biomechanical performance of several hardware constructs. METHODS: The study was performed using two validated finite element models of the lumbosacral spine (L1-S1) incorporating a PSO on L3 and L4, respectively...
November 17, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27857680/spiking-neural-networks-based-on-oxram-synapses-for-real-time-unsupervised-spike-sorting
#17
Thilo Werner, Elisa Vianello, Olivier Bichler, Daniele Garbin, Daniel Cattaert, Blaise Yvert, Barbara De Salvo, Luca Perniola
In this paper, we present an alternative approach to perform spike sorting of complex brain signals based on spiking neural networks (SNN). The proposed architecture is suitable for hardware implementation by using resistive random access memory (RRAM) technology for the implementation of synapses whose low latency (<1μs) enables real-time spike sorting. This offers promising advantages to conventional spike sorting techniques for brain-computer interfaces (BCI) and neural prosthesis applications. Moreover, the ultra-low power consumption of the RRAM synapses of the spiking neural network (nW range) may enable the design of autonomous implantable devices for rehabilitation purposes...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27851300/1665-a-shocking-case-of-a-lucas-mechanical-chest-compression-device-during-cardiac-arrest
#18
Lekshmi Santhosh, James Frank
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27812664/the-influence-of-assistive-technology-on-occupational-performance-and-satisfaction-of-leprosy-patients-with-grade-2-disabilities
#19
Lucas da Silva Muniz, Irmara Géssica Santos Amaral, Thiago da Silva Dias, Jorge Lopes Rodrigues
INTRODUCTION: We aimed to investigate the feasibility of assistive technology (AT) devices to improve leprosy patients' occupational performances and satisfaction. METHODS: This is a pretest-posttest design study. The Canadian Occupational Performance Measure was used to assess the occupational performance and satisfaction of five leprosy participants with grade 2 disabilities before and after ten 45-minute interventions using assistive technology devices. RESULTS: The data showed a statistically significant 7-point average improvement (p<0...
September 2016: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/27806066/prevalence-and-predictors-of-malnutrition-among-guatemalan-children-at-2-years-of-age
#20
Jason M Nagata, James Gippetti, Stefan Wager, Alejandro Chavez, Paul H Wise
OBJECTIVE: To identify the prevalence and predictors of malnutrition among 2-year old children in the Western Highlands of Guatemala. METHODS: Prospective cohort of 852 Guatemalan children in San Lucas Toliman, Guatemala followed from birth to age 2 from May 2008 to December 2013. Socio-demographic, anthropometric, and health data of children was collected at 2 month intervals. RESULTS: Among the 402 males and 450 females in the cohort, mean weight-for-age Z-score (WAZ) declined from -0...
2016: PloS One
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