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https://www.readbyqxmd.com/read/28107368/multi-channel-optical-coherence-elastography-using-relative-and-absolute-shear-wave-time-of-flight
#1
Eli Elyas, Alex Grimwood, Janine T Erler, Simon P Robinson, Thomas R Cox, Daniel Woods, Peter Clowes, Ramona De Luca, Franco Marinozzi, Jérémie Fromageau, Jeffrey C Bamber
Elastography, the imaging of elastic properties of soft tissues, is well developed for macroscopic clinical imaging of soft tissues and can provide useful information about various pathological processes which is complementary to that provided by the original modality. Scaling down of this technique should ply the field of cellular biology with valuable information with regard to elastic properties of cells and their environment. This paper evaluates the potential to develop such a tool by modifying a commercial optical coherence tomography (OCT) device to measure the speed of shear waves propagating in a three-dimensional (3D) medium...
2017: PloS One
https://www.readbyqxmd.com/read/28104306/midterm-and-one-year-outcome-of-amphilimus-polymer-free-drug-eluting-stent-in-patients-needing-short-dual-antiplatelet-therapy-insight-from-the-astute-registry-amphilimus-italian-multicenter-registry
#2
Cosmo Godino, Mauro Chiarito, Michael Donahue, Luca Testa, Riccardo Colantonio, Alberto Cappelletti, Alberto Monello, Valeria Magni, Diego Milazzo, Rosario Parisi, Annamaria Nicolino, Shahram Moshiri, Rossella Fattori, Gianfranco Aprigliano, Altin Palloshi, Giuseppe Caramanno, Matteo Montorfano, Francesco Bedogni, Carlo Briguori, Alberto Margonato, Antonio Colombo
BACKGROUND: To assess clinical outcomes of patients needing short dual antiplatelet therapy (S-DAPT) after PCI with Cre8 polymer-free amphilimus eluting-stent (AES). The Cre8-AES with pure i-Carbofilm coating was supposed to induce faster stent endothelialization and reduce device thrombogenicity. METHODS: We performed a sub-analysis of unrestricted consecutive patients treated with Cre8-AES between August 2011 and January 2015. Two groups were formed: 1) patients discharged with S-DAPT (≤3-month), because of high bleeding risk or attending urgent non-cardiac surgery; and 2) patients discharged with Recommended DAPT duration (R-DAPT; ≥6-month)...
January 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28102087/relationship-quality-of-persons-with-obstructive-sleep-apnoea-syndrome
#3
Francesco Tramonti, Michelangelo Maestri, Luca Carnicelli, Giulia Fava, Valentina Lombardi, Martina Rossi, Monica Fabbrini, Elisa Di Coscio, Elena Iacopini, Enrica Bonanni
In the field of sleep disorders, the quality of couple relationship is arousing increasing attention, given its implications for quality of life and treatment adherence. The aim of the present study was to evaluate relationship quality in a sample of treated or untreated patients with Obstructive Sleep Apnoea Syndrome. Eighty-seven patients were recruited in a hospital-based Centre for Sleep Medicine. Subjects were administered the Dyadic Adjustment Scale (DAS) to evaluate relationship quality, and the Epworth Sleepiness Scale (ESS)...
January 19, 2017: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/28094281/electrically-tunable-organic-inorganic-hybrid-polaritons-with-monolayer-ws2
#4
Lucas C Flatten, David M Coles, Zhengyu He, David G Lidzey, Robert A Taylor, Jamie H Warner, Jason M Smith
Exciton-polaritons are quasiparticles consisting of a linear superposition of photonic and excitonic states, offering potential for nonlinear optical devices. The excitonic component of the polariton provides a finite Coulomb scattering cross section, such that the different types of exciton found in organic materials (Frenkel) and inorganic materials (Wannier-Mott) produce polaritons with different interparticle interaction strength. A hybrid polariton state with distinct excitons provides a potential technological route towards in situ control of nonlinear behaviour...
January 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28092783/pulmonary-emboli-cardiac-arrest-with-cpr-complication-liver-laceration-and-massive-abdominal-bleed-a-case-report
#5
John Lundqvist, Jan G Jakobsson
INTRODUCTION: Massive pulmonary emboli may cause right ventricular failure and backward stasis with parenchymal organ swelling thus increasing the risk for laceration, e.g. if CPR is needed. PRESENTATION OF CASE: A 28-year-old Colombian female with no medical history but taking contraceptive pills and having had a recent longer flight was admitted to Danderyds hospital Emergency Department because of respiratory failure. She developed cardiac arrest in the emergence department following the emergent diagnosis of pulmonary emboli...
January 3, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28064352/pipeline-embolization-device-for-the-treatment-of-a-traumatic-intracranial-aneurysm-in-a-child
#6
Felipe Padovani Trivelato, Marco Túlio Salles Rezende, Luiz Venâncio Fonseca, Lucas Eduardo Bonadio, Alexandre Cordeiro Ulhôa, Daniel Giansante Abud
INTRODUCTION: Traumatic intracranial aneurysms in children are rare and may occur as the result of closed or penetrating head trauma. Their natural history seems to be more aggressive. Most traumatic aneurysms have complex shape, tending to have a large neck or even a fusiform morphology. CASE REPORT: We present a case of a traumatic carotid artery aneurysm in a 9-year-old girl that was successfully treated with pipeline embolization device. DISCUSSION: Due to its dissecting nature, wall friability and lack of a substantial neck can make surgical clipping and selective coiling difficult and risky...
January 7, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28057286/transcatheter-valve-in-ring-implantation%C3%A2-for-the-treatment-of-residual%C3%A2-or-recurrent-tricuspid-valve-dysfunction-after-prior-surgical-repair
#7
Jamil Aboulhosn, Allison K Cabalka, Daniel S Levi, Dominique Himbert, Luca Testa, Azeem Latib, Raj R Makkar, Younes Boudjemline, Dennis W Kim, Joelle Kefer, Sabine Bleiziffer, Gunter Kerst, Danny Dvir, Doff B McElhinney
OBJECTIVES: This study sought to describe the results of transcatheter tricuspid valve-in-ring (TVIR) implantation for treatment of tricuspid regurgitation (TR). BACKGROUND: Off-label use of transcatheter valves within surgically placed tricuspid annuloplasty prostheses has only been described in small reports. An international multicenter registry was developed to collect data on TVIR implantation. METHODS: Data were collected from 13 sites on 22 patients (5 to 69 years of age) with TR who underwent catheterization with the intent to perform TVIR implantation...
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28056743/antimicrobial-peptides-for-the-control-of-biofilm-formation
#8
Mercedes González Moreno, Lisa Lombardi, Mariagrazia Di Luca
Antimicrobial peptides (AMPs) are an abundant and varied group of molecules recognized as the most ancient components of the innate immune system. They are found in a wide group of organisms including bacteria, plants and animals as a defense mechanism against different kinds of infectious pathogens. Over the past two decades, a fast-growing number of AMPs have been identified/designed and their wide-spectrum antimicrobial activity has been deeply investigated. In recent years, there has been an increasing interest in the use of AMPs as alternative anti-biofilm molecules for the control of biofilm-related infections...
January 5, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/28047673/su-d-207a-06-pediatric-abdominal-organ-motion-quantified-via-a-novel-4d-mri-method
#9
J Uh, M J Krasin, J T Lucas, C Tinkle, T E Merchant, C Hua
PURPOSE: To develop a 4D MRI method for assessing respiration-induced abdominal organ motion in children receiving radiation therapy. METHODS: A 4D MRI using internal image-based respiratory surrogate has been developed and implemented on a clinical scanner (1.5T Siemens Avanto). Ten patients (younger group: N=6, 2-5 years, anesthetized; older group: N=4, 11-15 years) with neuroblastoma, Wilm's tumor rhabdomyosarcoma, or desmoplastic small round cell tumor received free breathing 4D MRI scans for treatment planning...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28041702/can-we-predict-new-af-occurrence-in-single-chamber-icd-patients-insights-from-an-observational-investigation
#10
Mauro Biffi, Matteo Ziacchi, Renato Pietro Ricci, Domenico Facchin, Giovanni Morani, Maurizio Landolina, Maurizio Lunati, Saverio Iacopino, Alessandro Capucci, Stefano Bianchi, Tommaso Infusino, Giovanni Luca Botto, Luigi Padeletti, Giuseppe Boriani
BACKGROUND: Atrial tachyarrhythmias (AT/AF) have been associated with an increased risk of mortality, morbidity and ischemic stroke. Up to now, single chamber ICD diagnostics was not able to detect AT/AF, therefore the incidence of new onset AT/AF in patients with single chamber ICD is not known. OBJECTIVE: To evaluate incidence and predictors of AT/AF occurrence in patients with dual-chamber ICD with no pacing indications and no history of AT/AF that strictly mimic single chamber ICD recipient...
December 22, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28040091/reconstruction-of-patellar-tendon-following-implantation-of-proximal-tibia-megaprosthesis-for-the-treatment-of-post-traumatic-septic-bone-defects
#11
Giorgio M Calori, Emilio Luigi Mazza, Luca Vaienti, Simone Mazzola, Alessandra Colombo, Luca Gala, Massimiliano Colombo
INTRODUCTION: Latest advances made in joint replacement implants allows reconstruction of entire limbs. These special prostheses or megaprostheses were originally designed for the treatment of severe oncological bone loss. Nowadays, however, the indications and applications of these devices are expanding to other orthopaedic and trauma clinical conditions. Since 2008 we have implanted 152 megaprostheses in non-oncological conditions: 87 were implanted for post-traumatic failures aseptic/septic (represented by complex non-unions and critical size bone defects); 26 total femur, 52 distal femur and 9 proximal tibia...
December 2016: Injury
https://www.readbyqxmd.com/read/28039539/a-wearable-proprioceptive-stabilizer-for-rehabilitation-of-limb-and-gait-ataxia-in-hereditary-cerebellar-ataxias-a-pilot-open-labeled-study
#12
Luca Leonardi, Maria Gabriella Aceto, Christian Marcotulli, Giuseppe Arcuria, Mariano Serrao, Francesco Pierelli, Paolo Paone, Alessandro Filla, Alessandro Roca, Carlo Casali
The aim of this pilot study is to test the feasibility and effectiveness of a wearable proprioceptive stabilizer that emits focal mechanical vibrations in patients affected by hereditary cerebellar ataxias. Eleven adult patients with a confirmed genetic diagnosis of autosomal dominant spinocerebellar ataxia or Friedreich's ataxia were asked to wear an active device for 3 weeks. Assessments were performed at baseline, after the device use (T1), and 3 weeks after (T2). SARA, 9-HPT, PATA, 6MWT, and spatial and temporal gait parameters, measured with a BTS-G-Walk inertial sensor, were used as study endpoints...
December 31, 2016: Neurological Sciences
https://www.readbyqxmd.com/read/28035838/efficacy-of-auxiliary-devices-for-removal-of-fluorescent-residue-after-bracket-debonding
#13
Rafael Santos Rocha, Fabio Martins Salomão, Lucas Silveira Machado, Renato Herman Sundfeld, Ticiane Cestari Fagundes
OBJECTIVE: To evaluate four protocols for removal of fluorescent materials after bracket debonding. MATERIALS AND METHODS: Resin removal from 40 bovine enamel surfaces was performed according to groups (n = 10): conventional (C), white LED (W), LED that evidenced fluorescence (F), and fluorescent lens (FL). The following analyses were performed: sample thickness, superficial area of resin residue, and areas of resin residue or worn enamel in depth. ANOVA and Tukey tests were used to analyze sample thickness (P ≤ ...
December 30, 2016: Angle Orthodontist
https://www.readbyqxmd.com/read/28026914/synthetic-vs-natural-diatoms-bioderived-porous-materials-for-the-next-generation-of-healthcare-nanodevices
#14
Ilaria Rea, Monica Terracciano, Luca De Stefano
Nanostructured porous materials promise a next generation of innovative devices for healthcare and biomedical applications. The fabrication of such materials generally requires complex synthesis procedures, not always available in laboratories or sustainable in industries, and has adverse environmental impact. Nanosized porous materials can also be obtained from natural resources, which are an attractive alternative approach to man-made fabrication. Biogenic nanoporous silica from diatoms, and diatomaceous earths, constitutes largely available, low-cost reservoir of mesoporous nanodevices that can be engineered for theranostic applications, ranging from subcellular imaging to drug delivery...
December 27, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28025187/percutaneous-repair-of-ascending-aorta-pseudoaneurysm-and-aortopulmonary-fistula-with-two-amplatzer-septal-occluder-devices
#15
Giuseppe Tarantini, Umberto Cucchini, Luca Nai Fovino
No abstract text is available yet for this article.
December 23, 2016: European Heart Journal
https://www.readbyqxmd.com/read/28024591/modulation-of-electrostatic-interactions-to-improve-controlled-drug-delivery-from-nanogels
#16
Emanuele Mauri, Giulia M F Chincarini, Riccardo Rigamonti, Luca Magagnin, Alessandro Sacchetti, Filippo Rossi
The synthesis of nanogels as devices capable to maintain the drug level within a desired range for a long and sustained period of time is a leading strategy in controlled drug delivery. However, with respect to the good results obtained with antibodies and peptides there are a lot of problems related to the quick and uncontrolled diffusion of small hydrophilic molecules through polymeric network pores. For these reasons research community is pointing toward the use of click strategies to reduce release rates of the linked drugs to the polymer chains...
March 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28011803/the-italian-subcutaneous-implantable-cardioverter-defibrillator-survey-s-icd-why-not
#17
Giovanni Luca Botto, Giovanni B Forleo, Alessandro Capucci, Francesco Solimene, Antonello Vado, Giovanni Bertero, Pietro Palmisano, Ennio Pisanò, Antonio Rapacciuolo, Tommaso Infusino, Alessandro Vicentini, Miguel Viscusi, Paola Ferrari, Antonello Talarico, Giovanni Russo, Giuseppe Boriani, Luigi Padeletti, Mariolina Lovecchio, Sergio Valsecchi, Antonio D'Onofrio
AIMS: A recommendation for a subcutaneous-implantable cardioverter-defibrillator (S-ICD) has been added to recent European Society of Cardiology Guidelines. However, the S-ICD is not ideally suitable for patients who need pacing. The aim of this survey was to analyse the current practice of ICD implantation and to evaluate the actual suitability of S-ICD. METHODS AND RESULTS: The survey 'S-ICD Why Not?' was an independent initiative taken by the Italian Heart Rhythm Society (AIAC)...
December 23, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28009498/resonant-gain-singularities-in-1d-and-3d-metal-dielectric-multilayered-nanostructures
#18
Vincenzo Caligiuri, Luigia Pezzi, Alessandro Veltri, Antonio De Luca
We present a detailed study on the resonant gain (RG) phenomena occurring in two nanostructures, in which the presence of dielectric singularities is used to reach a huge amplification of the emitted photons resonantly interacting with the system. The presence of gain molecules in the considered nanoresonator systems makes it possible to obtain optical features that are able to unlock several applications. Two noticeable cases have been investigated: a 1D nanoresonator based on hyperbolic metamaterials and a 3D metal/dielectric spherical multishell...
December 30, 2016: ACS Nano
https://www.readbyqxmd.com/read/28005333/spin-orbit-coupling-induced-gap-in-graphene-on-pt-111-with-intercalated-pb-monolayer
#19
Ilya I Klimovskikh, Mikhail M Otrokov, Vladimir Yu Voroshnin, Daria Sostina, Luca Petaccia, Giovanni Di Santo, Sangeeta Thakur, Evgueni V Chulkov, Alexander M Shikin
Graphene is one of the most promising materials for nanoelectronics owing to its unique Dirac cone-like dispersion of the electronic state and high mobility of the charge carriers. However, to facilitate the implementation of the graphene-based devices, an essential change of its electronic structure, a creation of the band gap should controllably be done. Brought about by two fundamentally different mechanisms, a sublattice symmetry breaking or an induced strong spin-orbit interaction, the band gap appearance can drive graphene into a narrow-gap semiconductor or a 2D topological insulator phase, respectively, both cases being technologically relevant...
December 22, 2016: ACS Nano
https://www.readbyqxmd.com/read/28000520/small-bowel-villous-atrophy-celiac-disease-and-beyond
#20
Luca Elli, Federica Branchi, Reena Sidhu, Stefano Guandalini, Asaad Assiri, Firas Rinawi, Raanan Shamir, Prasenjit Das, Govind K Makharia
Small bowel villous atrophy can represent a diagnostic challenge for gastroenterologists and pathologists. In Western countries small bowel atrophy and mild non-atrophic alterations are frequently caused by celiac disease. However, other pathology can mimic celiac disease microscopically, widening the differential diagnosis. The several novelties on this topic and the introduction of the device-assisted enteroscopy in the diagnostic flowchart make an update of the literature necessary. Areas covered: In this review, a description of the different clinical scenarios when facing with small bowel mucosal damage, particularly small bowel atrophy, is described...
December 29, 2016: Expert Review of Gastroenterology & Hepatology
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