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Lucas Device

Angel Fernandez-Bravo, Kaiyuan Yao, Edward S Barnard, Nicholas J Borys, Elizabeth S Levy, Bining Tian, Cheryl A Tajon, Luca Moretti, M Virginia Altoe, Shaul Aloni, Kenes Beketayev, Francesco Scotognella, Bruce E Cohen, Emory M Chan, P James Schuck
Reducing the size of lasers to microscale dimensions enables new technologies 1 that are specifically tailored for operation in confined spaces ranging from ultra-high-speed microprocessors 2 to live brain tissue 3 . However, reduced cavity sizes increase optical losses and require greater input powers to reach lasing thresholds. Multiphoton-pumped lasers4-7 that have been miniaturized using nanomaterials such as lanthanide-doped upconverting nanoparticles (UCNPs) 8 as lasing media require high pump intensities to achieve ultraviolet and visible emission and therefore operate under pulsed excitation schemes...
June 18, 2018: Nature Nanotechnology
Bradley A Moores, Lucas R Sletten, Jeremie J Viennot, K W Lehnert
We demonstrate an acoustical analog of a circuit quantum electrodynamics system that leverages acoustic properties to enable strong multimode coupling in the dispersive regime while suppressing spontaneous emission to unconfined modes. Specifically, we fabricate and characterize a device that comprises a flux tunable transmon coupled to a 300  μm long surface acoustic wave resonator. For some modes, the qubit-cavity coupling reaches 6.5 MHz, exceeding the cavity loss rate (200 kHz), qubit linewidth (1...
June 1, 2018: Physical Review Letters
Lucas Tramèr, Christoph Becker, Seraina Hochstrasser, Stephan Marsch, Sabina Hunziker
BACKGROUND: Performance of cardiopulmonary resuscitation (CPR) causes significant mental stress for rescuers, especially if performed by inexperienced individuals. Our aim was to study electrocardiogram (ECG) alterations in rescuers and its association with gender and CPR performance. METHODS: We included 126 medical students in this prospective, observational simulator study. Each student was equipped with a 3-lead continuous ECG device tracking the individual electrocardiographic output before, during and after CPR...
2018: PloS One
Benjamin Torner, Lucas Konnigk, Sebastian Hallier, Jitendra Kumar, Matthias Witte, Frank-Hendrik Wurm
PURPOSE: Numerical flow analysis (computational fluid dynamics) in combination with the prediction of blood damage is an important procedure to investigate the hemocompatibility of a blood pump, since blood trauma due to shear stresses remains a problem in these devices. Today, the numerical damage prediction is conducted using unsteady Reynolds-averaged Navier-Stokes simulations. Investigations with large eddy simulations are rarely being performed for blood pumps. Hence, the aim of the study is to examine the viscous shear stresses of a large eddy simulation in a blood pump and compare the results with an unsteady Reynolds-averaged Navier-Stokes simulation...
June 1, 2018: International Journal of Artificial Organs
Maria Grazia Bongiorni, Veronica Della Tommasina, Valentina Barletta, Andrea Di Cori, Sara Rogani, Stefano Viani, Luca Segreti, Luca Paperini, Ezio Soldati, Raffaele De Lucia, Giulio Zucchelli
Aims: To demonstrate the feasibility and long-term performances of a non-apical Micra pacemaker implantation. Methods and results: Fifty-two consecutive patients underwent Micra implantation, targeting a non-apical site of delivery when feasible. Each patient received a regular follow-up (mean 13 ± 9 months). The first 17 patients were also enrolled in the Micra transcatheter pacing system trial (Group 1); the remaining ones presented broader indications and included post-extraction subjects (Group 2)...
June 8, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Angela Riccio, Francesca Schettini, Luca Simione, Alessia Pizzimenti, Maurizio Inghilleri, Marta Olivetti-Belardinelli, Donatella Mattia, Febo Cincotti
Our objective was to investigate the capacity to control a P3-based brain-computer interface (BCI) device for communication and its related (temporal) attention processing in a sample of amyotrophic lateral sclerosis (ALS) patients with respect to healthy subjects. The ultimate goal was to corroborate the role of cognitive mechanisms in event-related potential (ERP)-based BCI control in ALS patients. Furthermore, the possible differences in such attentional mechanisms between the two groups were investigated in order to unveil possible alterations associated with the ALS condition...
2018: Frontiers in Human Neuroscience
Longtu Chen, Ruth F Lucas, Bin Feng
Breastfeeding is optimal for infant health, but more than 66% of mothers cease exclusive breastfeeding within three months after giving birth. Evaluating infants' sucking effort provides valuable diagnosis to mothers encountering barriers with breastfeeding. Sucking microstructure is defined as an array of metrics that comprehensively capture infants' ability to create a sealed latch onto mother's nipple and regulate feeding, including number of sucks, sucks per burst, number of bursts, intra suck interval, and maximal sucking pressure...
2018: IEEE Journal of Translational Engineering in Health and Medicine
Giuseppe Tarantini, Giulia Masiero, Luca Nai Fovino, Marco Mojoli, Attilio Varricchio, Bruno Loi, Roberto Gistri, Leonardo Misuraca, Gabriele Gabrielli, Bernardo Cortese, Francesco Pisano, Luciano Moretti, Gabriele Tumminello, Zoran Olivari, Pietro Mazzarotto, Alessandro Colombo, Paolo Calabrò, Annamaria Nicolino, Paola Tellaroli, Donatella Corrado, Alessandro Durante, Giuseppe Steffenino
OBJECTIVES: The objective of this study was to investigate mid-term clinical outcomes of patients treated with 'full-plastic jacket' (FPJ) everolimus-eluting Absorb bioresorbable vascular scaffold (BRS) implantation. BACKGROUND: FPJ with BRS may represent an interesting option for patient with diffuse coronary artery disease (CAD), but data on the clinical impact of FPJ using the Absorb BRS are scant. METHODS: FPJ was defined as the implantation of >56 mm of overlapping BRS in at least one vessel...
September 1, 2018: International Journal of Cardiology
Lucas Lavo António Jimo Miguel
Little is known about the dynamics of particulate inorganic and organic matter in brackish water controlled by tidal prism and seasonal river discharges in Macuse estuary, on central Mozambique coast, southern Africa. This manuscript illustrates seasonal variation of biogeochemical flow dynamics in a tropical estuarine system in Zambézia province. The data were collected at 42 stations, including tidal current measurements with an Acoustic Doppler Current Profiler, tidal elevation with a tidal-gauge and nitrate, silicate (SiO2 ), dissolved oxygen and chlorophyll-a with a photometer device system and tidal currents with multisensory instrument device (Current, Temperature and Depth device)...
June 2018: Marine Pollution Bulletin
Gian Nicola Angotzi, Mario Malerba, Fabio Boi, Ermanno Miele, Alessandro Maccione, Hayder Amin, Marco Crepaldi, Luca Berdondini
Electrophysiological signals in the brain are distributed over broad spatial and temporal scales. Monitoring these signals at multiple scales is fundamental in order to decipher how brain circuits operate and might dysfunction in disease. A possible strategy to enlarge the experimentally accessible spatial and temporal scales consists in combining the use of multiple probes with different resolutions and sensing areas. Here, we propose a neural recording system capable of simultaneous and synchronous acquisitions from a new generation of high-resolution CMOS probes (512 microelectrodes, 25 kHz/electrode whole-array sampling frequency) as well as from a custom-designed CMOS-based headstage...
June 2018: IEEE Transactions on Biomedical Circuits and Systems
David James Davies, Michael Clancy, Hamid Dehghani, Samuel John Edwin Lucas, Mario Forcione, Kamal Makram Yakoub, Antonio Belli
The cost and highly invasive nature of brain monitoring modality in traumatic brain injury patients currently restrict its utility to specialist neurological intensive care settings. We aim to test the abilities of a frequency domain near-infrared spectroscopy (FD-NIRS) device in predicting changes in invasively measured brain tissue oxygen tension. Individuals admitted to a United Kingdom specialist major trauma centre were contemporaneously monitored with an FD-NIRS device and invasively measured brain tissue oxygen tension probe...
June 7, 2018: Journal of Neurotrauma
Emma-Louise Cole, James J Waggitt, Anders Hedenstrom, Marco Piano, Mark D Holton, Luca Börger, Emily L C Shepard
Animal-attached technologies can be powerful means to quantify space-use and behaviour, however, there are also ethical implications associated with capturing and instrumenting animals. Furthermore, tagging approaches are not necessarily well-suited for examining the movements of multiple individuals within specific, local areas of interest. Here, we assess a method of quantifying animal space use based on a modified theodolite with an inbuilt laser rangefinder. Using a database of > 4,200 tracks of migrating birds, we show that detection distance increases with bird body mass (range 5 g - >10 kg)...
May 31, 2018: Integrative Zoology
Valeria Mondini, Anna Lisa Mangia, Luca Talevi, Angelo Cappello
Canonical Correlation Analysis (CCA) is an increasingly used approach in the field of Steady-State Visually Evoked Potential (SSVEP) recognition. The efficacy of the method has been widely proven, and several variations have been proposed. However, most CCA variations tend to complicate the method, usually requiring additional user training or increasing computational load. Taking simple procedures and low computational costs may be, however, a relevant aspect, especially in view of low-cost and high-portability devices...
2018: Computational Intelligence and Neuroscience
Michele Torella, Iolanda Aquila, Paolo Chiodini, Cristiano Amarelli, Gianpaolo Romano, Ester Elena Della Ratta, Marisa De Feo, Alessandro Della Corte, Ciro Indolfi, Daniele Torella, Luca Salvatore De Santo
Thromboembolic complications after cardiac valve replacement are due to a complex interplay between patients' characteristics, device features and anticoagulation intensity. Subtle design and material differences in available prostheses may thrombosis. We conducted a post-hoc sub-analysis of the LOWERING-IT database to test the safety and feasibility of a low-level oral anticoagulant regime in low-risk patients with aortic LivaNova prosthetic valve replacement. The study population included 148 patients randomized to a low INR target (1...
May 30, 2018: Scientific Reports
Anna Urciuolo, Luca Urbani, Silvia Perin, Panagiotis Maghsoudlou, Federico Scottoni, Asllan Gjinovci, Henry Collins-Hooper, Stavros Loukogeorgakis, Athanasios Tyraskis, Silvia Torelli, Elena Germinario, Mario Enrique Alvarez Fallas, Carla Julia-Vilella, Simon Eaton, Bert Blaauw, Ketan Patel, Paolo De Coppi
Pathological conditions affecting skeletal muscle function may lead to irreversible volumetric muscle loss (VML). Therapeutic approaches involving acellular matrices represent an emerging and promising strategy to promote regeneration of skeletal muscle following injury. Here we investigated the ability of three different decellularised skeletal muscle scaffolds to support muscle regeneration in a xenogeneic immune-competent model of VML, in which the EDL muscle was surgically resected. All implanted acellular matrices, used to replace the resected muscles, were able to generate functional artificial muscles by promoting host myogenic cell migration and differentiation, as well as nervous fibres, vascular networks, and satellite cell (SC) homing...
May 30, 2018: Scientific Reports
Ada Della Pia, Simone Lisi, Oreste De Luca, Daniel Warr, James Lawrence, Mikhail Otrokov, Ziya Aliev, Evgueni Chulkov, Raffaele Agostino, Andrés Arnau, Marco Papagno, Giovanni Costantini
Topological insulators are promising candidates for spintronic applications due to their topologically protected, spin-momentum locked and gapless surface states. The breaking of the time-reversal symmetry after the introduction of magnetic impurities, such as 3d transition metal atoms embedded in two-dimensional molecular networks, could lead to several phenomena interesting for device fabrication. The first step towards the fabrication of metal-organic coordination networks on the surface of a topological insulator is to investigate the adsorption of the pure molecular layer, which is the aim of this study...
May 30, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
Akili K Kalinga, Charles Mwanziva, Sarah Chiduo, Christopher Mswanya, Deus I Ishengoma, Filbert Francis, Lucky Temu, Lucas Mahikwano, Saidi Mgata, George Amoo, Lalaine Anova, Eyako Wurrapa, Nora Zwingerman, Santiago Ferro, Geeta Bhat, Ian Fine, Brian Vesely, Norman Waters, Mara Kreishman-Deitrick, Mark Hickman, Robert Paris, Edwin Kamau, Colin Ohrt, Reginald A Kavishe
BACKGROUND: Although microscopy is a standard diagnostic tool for malaria and the gold standard, it is infrequently used because of unavailability of laboratory facilities and the absence of skilled readers in poor resource settings. Malaria rapid diagnostic tests (RDT) are currently used instead of or as an adjunct to microscopy. However, at very low parasitaemia (usually < 100 asexual parasites/µl), the test line on malaria rapid diagnostic tests can be faint and consequently hard to visualize and this may potentially affect the interpretation of the test results...
May 29, 2018: Malaria Journal
Luca Barresi, Stefano F Crinò, Carlo Fabbri, Fabia Attili, Jan W Poley, Silvia Carrara, Ilaria Tarantino, Laura Bernardoni, Silvia Giovanelli, Milena Di Leo, Erminia Manfrin, Matteo Tacelli, Marco J Bruno, Mario Traina, Alberto Larghi
BACKGROUND AND AIMS: Tissue acquisition in pancreatic cystic lesions (PCLs) is the ideal method for diagnosis and risk stratification for malignancy of these lesions. Direct sampling from the walls of PCLs with different devices has shown better results than cytology from cystic fluid. We carried out a retrospective, multicenter study to evaluate the feasibility, safety, and diagnostic yield of a micro forceps, specifically designed to be used through a 19-gauge needle after EUS-guided puncture of PCL...
May 29, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Thomas M Kessler, Luca R Traini, Blayne Welk, Marc P Schneider, Jeffrey Thavaseelan, Armin Curt
PURPOSE: Considering the major clinical challenges of managing patients with spinal cord injury (SCI), we summarized the relevant aspects of the early (within 1 year after SCI) neurological care emphasizing common standards. METHODS: This review was performed according to the methodology recommended by the Joint SIU-ICUD International Consultation. Embase and Medline databases were used to identify literature relevant to the early neurological care of SCI patients...
May 28, 2018: World Journal of Urology
Julien Regamey, Matthias Kirsch, Piergiorgio Tozzi, Nicolas Barras, Carlo Marcucci, Lucas Liaudet, Roger Hullin, Patrick Yerly
Despite the benefit of the drugs acting on neuro-humoral activation and cardiac resynchronization therapy, some patients will end in a severe refractory form of heart failure: advanced heart failure. The only therapeutic options with a positive impact on mortality and quality of life are heart transplantation and permanent left ventricular assist device (LVAD). The significant technological improvements of the past 20 years lead to a reduction of the complications associated with these devices, which now allow their use not only during the waiting period preceding heart transplantation (bridge to transplant), but also as a durable therapeutic option (destination therapy)...
May 23, 2018: Revue Médicale Suisse
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