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https://www.readbyqxmd.com/read/27913001/cancer-related-fatigue-persistent-pervasive-and-problematic
#1
REVIEW
Lynn H Gerber
Cancer-related fatigue (CRF) is commonly reported by patients with cancer before, during, and after treatment. It is a persistent sense of tiredness that interferes with function, is distressing, and requires monitoring and, possibly, treatment. Fatigue assessment requires objective measures and self-reports, such as Functional Assessment of Cancer Therapy-Fatigue. Significant contributors to CRF include anemia, pain, insomnia, depressive symptoms, and elevated BMI. Elevated inflammatory cytokines, diabetes mellitus, cortisol, and cellular dysregulation have been associated with CRF...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27911316/risk-factors-for-mild-cognitive-impairment-in-german-primary-care-practices
#2
Louis Jacob, Jens Bohlken, Karel Kostev
BACKGROUND: Mild cognitive impairment (MCI) is a common mental disorder affecting around 16% of elderly people without dementia. MCI is considered an intermediate state between normal cognition and dementia. OBJECTIVE: To analyze risk factors for the development of MCI in German primary care practices. METHODS: In total, 3,604 MCI patients and 3,604 controls without MCI were included between January 2010 and December 2015. Several disorders potentially associated with MCI were determined...
December 1, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27911049/family-partners-in-lifestyle-support-pals-family-based-weight-loss-for-african-american-adults-with-type-2-diabetes
#3
Carmen D Samuel-Hodge, Judith C Holder-Cooper, Ziya Gizlice, Gwendolyn Davis, Sonia P Steele, Thomas C Keyserling, Shiriki K Kumanyika, Phillip J Brantley, Laura P Svetkey
OBJECTIVE: To develop and test a family-centered behavioral weight loss intervention for African American adults with type 2 diabetes. METHODS: In this randomized trial, dyads consisting of an African American adult with overweight or obesity and type 2 diabetes (index participant) paired with a family partner with overweight or obesity but not diagnosed with diabetes were assigned in a 2:1 ratio to a 20-week special intervention (SI) or delayed intervention (DI) control group...
December 2, 2016: Obesity
https://www.readbyqxmd.com/read/27910808/magnesium-and-depression
#4
Anna Serefko, Aleksandra Szopa, Ewa Poleszak
Magnesium is one of the most important elements in the human body and is involved in a number of biochemical processes crucial for the proper functioning of the cardiovascular, alimentary, endocrine, and osteoarticular systems. It also plays a vital modulatory role in brain biochemistry, influencing several neurotransmission pathways associated with the development of depression. Personality changes, including apathy, depression, agitation, confusion, anxiety, and delirium are observed when there is a deficiency of this element...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27904642/disturbed-eating-behavior-in-iranian-adolescent-and-young-females-with-type-1-diabetes-compared-to-non-diabetic-peers-a-cross-sectional-study
#5
Hamid Reza Roohafza, Zahra Abdeyazdan, Parvaneh Amini, Saied Pahlavanzadeh, Pedram Shokouh
BACKGROUND: An association of eating disorder with diabetes mellitus may lead to a serious lack of metabolic control, higher mortality and morbidity. There is no recent study conducted in the Iranian population about eating disorder and its variants. The aim of the present study is investigation of frequency of disturbed eating behaviors in adolescent girls with type 1 diabetes mellitus (T1DM) compared to non-diabetics. MATERIALS AND METHODS: In this cross-sectional study, disturbed eating behavior were evaluated and compared in two groups of 12-22 year old adolescent and young females (126 with diabetes and 325 without diabetes)...
September 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/27901243/stages-of-hyperglycemia-and-common-mental-disorders-in-adults-the-brazilian-study-of-adult-health-elsa-brasil
#6
Marina Bessel, Álvaro Vigo, Andréa Poyastro, Maria Angélica Nunes, Bruce Bartholow Duncan, Maria Inês Schmidt
CONTEXT AND OBJECTIVE: Diabetes mellitus and depressive disorders frequently coexist. However, this relationship has been little evaluated across stages of hyperglycemia and for a broad range of common mental disorders (CMDs). The objective here was to investigate the association between CMDs and stages of glycemia. DESIGN AND SETTING: Cross-sectional study conducted among civil servants aged 35-74 years participating in the ELSA-Brasil cohort. METHODS: CMDs were classified using the Clinical Interview Schedule - Revised (CIS-R)...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27900466/overview-of-the-impact-of-depression-and-anxiety-in-chronic-obstructive-pulmonary-disease
#7
Josep Montserrat-Capdevila, Pere Godoy, Josep Ramon Marsal, Ferran Barbé, Josep Pifarré, Miquel Alsedà, Marta Ortega
BACKGROUND: Anxiety and depression are common entities in patients diagnosed with COPD. However, the impact that they have on the exacerbation of illness is scarcely studied. OBJECTIVE: To determine if the presence of anxiety and depression is associated with a greater risk of frequent exacerbation (≥2 per year) in patients diagnosed with COPD. PATIENTS AND METHODS: A cohort study that analysed frequent exacerbation and associated factors in 512 patients monitored during 2 years...
November 29, 2016: Lung
https://www.readbyqxmd.com/read/27899129/a-community-based-study-on-prevalence-and-correlates-of-erectile-dysfunction-among-kinondoni-district-residents-dar-es-salaam-tanzania
#8
Pedro Pallangyo, Paulina Nicholaus, Peter Kisenge, Henry Mayala, Noel Swai, Mohamed Janabi
BACKGROUND: Globally, erectile dysfunction burden (ED) is rising appreciably and it is projected to affect about 332 million men by the year 2025. This rise is attributable to the rising incidence of conditions associated with ED including obesity, diabetes, hypertension, coronary artery disease and depression. We conducted this community-based screening to elucidate on the prevalence of ED and its associated factors among men residing in an urban community in Tanzania. METHODS: We conducted a cross-sectional community-based study and interviewed 441 men aged at least 18 years...
November 29, 2016: Reproductive Health
https://www.readbyqxmd.com/read/27897469/a-randomized-controlled-trial-investigating-a-paraprofessional-led-self-management-coaching-program-for-community-dwelling-patients-with-type-2-diabetes-prescribed-insulin
#9
Tim Pauley, Judith Gargaro, Glen Chenard, Helen Cavanagh, Sandra M McKay
This study evaluated paraprofessional-led diabetes self-management coaching (DSMC). Subjects were randomized to standard care or standard care plus coaching. Measures included the Diabetes Self-Efficacy Scale (DSES), Insulin Management Self-Efficacy Scale (IMDSES), and Hospital Anxiety and Depression Scale (HADS). Both groups improvement in DSES (6.6 + 1.5 vs. 7.2 + 1.5, p < .001) and IMDSES (113.5 + 20.6 vs. 125.7 + 22.3, p < .001); there were no between-groups differences. There were no between-groups differences in anxiety (p > ...
November 29, 2016: Home Health Care Services Quarterly
https://www.readbyqxmd.com/read/27895824/relationship-between-depression-and-diabetes-in-pregnancy-a-systematic-review
#10
Glynis P Ross, Henrik Falhammar, Roger Chen, Helen Barraclough, Ole Kleivenes, Ian Gallen
AIM: To systematically review the literature on women with both diabetes in pregnancy (DIP) and depression during or after pregnancy. METHODS: In this systematic literature review, PubMed/MEDLINE and EMBASE were searched (13 November 2015) using terms for diabetes (type 1, type 2, or gestational), depression, and pregnancy (no language or date restrictions). Publications that reported on women who had both DIP (any type) and depression or depressive symptoms before, during, or within one year after pregnancy were considered for inclusion...
November 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27894461/does-mindfulness-based-cognitive-therapy-benefit-all-people-with-diabetes-and-comorbid-emotional-complaints-equally-moderators-in-the-diamind-trial
#11
Ivan Nyklíček, Jenny van Son, Victor J Pop, Johan Denollet, François Pouwer
OBJECTIVES: Research has shown the effectiveness of mindfulness-based interventions for a variety of emotional problems in different samples, but it is unknown which factors influence this effectiveness. Therefore, the aim of the current study was: which factors (demographic, personality, and baseline levels of mindfulness skills) moderate the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT)? METHODS: Outpatients with diabetes (type 1 or type 2; N=139) and an elevated level of emotional distress participated in the Diabetes and Mindfulness (DiaMind) trial...
December 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27893672/risk-factors-of-severe-hypoglycemia-requiring-medical-assistance-and-neurological-sequelae-in-patients-with-diabetes-a-case-control-study
#12
Ja Young Jeon, Se Ran Kim, Hae Jin Kim, Dae Jung Kim, Kwan-Woo Lee, Jung-Dong Lee, Seung Jin Han
Hypoglycemia commonly occurs in patients who are being treated for diabetes. In some cases, these patients suffer from severe hypoglycemia that requires medical assistance and which can unfortunately result in long-term disabilities. Therefore, we investigated risk factors associated with severe hypoglycemia requiring medical assistance (HMA) and the resulting neurological sequelae in patients with diabetes. This investigation was a case-control study that assessed 129 patients with diabetes and documented hypoglycemia from a single tertiary hospital between February 2013 and May 2015...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27892613/depressive-symptoms-prediabetes-and-incident-diabetes-in-older-english-adults
#13
Eva Graham, Bonnie Au, Norbert Schmitz
OBJECTIVE: The objective of this study was to assess the risk of diabetes in older adults with elevated depressive symptoms, prediabetes, or both. METHOD: This study included 4129 participants from the English Longitudinal Study of Ageing. Participants were followed from Wave 2 (2004-2005) to Wave 6 (2012-2013). The 8-item Centre for Epidemiologic Studies Depression (CESD) scale was used to measure depressive symptoms in the past week, which were categorized as no/low, mild, or high...
November 28, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27891676/sex-dependent-independent-prediction-of-incident-diabetes-by-depressive-symptoms
#14
Tuğba Akbaş-Şimşek, Altan Onat, Adnan Kaya, Eyyup Tusun, Hüsniye Yüksel, Günay Can
OBJECTIVE: To study the predictive value of depressive symptoms (DeprSs) in a general population of Turkey for type 2 diabetes. METHODS: Responses to three questions served to assess the sense of depression. Cox regression analyses were used regarding risk estimates for incident diabetes, after exclusion of prevalent cases of diabetes. Mean follow-up consisted of 5.15 (±1.4) years. RESULTS: Depressive symptoms were present at baseline in 16...
November 28, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27889401/clinical-and-psychosocial-outcomes-of-a-structured-transition-program-among-young-adults-with-type-1-diabetes
#15
Elizabeth A Pyatak, Paola A Sequeira, Cheryl L P Vigen, Marc J Weigensberg, Jamie R Wood, Lucy Montoya, Valerie Ruelas, Anne L Peters
PURPOSE: We identified and treated young adults with type 1 diabetes who had been lost to follow-up during their transfer from pediatric to adult care, comparing their clinical, psychosocial, and health care utilization outcomes to participants receiving continuous care (CC) throughout the transition to adult care. METHODS: Individuals in their last year of pediatric care (CC group, n = 51) and individuals lost to follow-up in the transfer to adult care ("lapsed care" [LC] group, n = 24) were followed prospectively for 12 months...
November 23, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27889117/inadequate-pain-relief-among-patients-with-primary-knee-osteoarthritis
#16
Pedro A Laires, Jorge Laíns, Luís C Miranda, Rui Cernadas, Srini Rajagopalan, Stephanie D Taylor, José C Silva
BACKGROUND: Despite the widespread treatments for Osteoarthritis (OA), data on treatment patterns, adequacy of pain relief, and quality of life are limited. The prospective multinational Survey of Osteoarthritis Real World Therapies (SORT) was designed to investigate these aspects. OBJECTIVES: To analyze the characteristics and the patient reported outcomes of the Portuguese dataset of SORT at the start of observation. METHODS: Patients ≥ 50 years with primary knee OA who were receiving oral or topical analgesics were eligible...
October 28, 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27888118/increased-risk-of-new-onset-fibromyalgia-among-chronic-osteomyelitis-patients-evidence-from-a-taiwan-cohort-study
#17
Jiunn-Horng Chen, Chih-Hsin Muo, Chia-Hung Kao, Chon-Haw Tsai, Chun-Hung Tseng
: Chronic inflammation, which changes the neurotransmitter metabolism and kindles neuroendocrine system dysfunction in central nervous system, might cause fibromyalgia (FM) formation. In FM patients without traditional FM risk factors, such as hypertension, hyperlipidemia, diabetes, sleep disorder, depression, and anxiety, chronic inflammatory process is a possible risk factor for FM. Thus, we investigated whether chronic osteomyelitis (COM), a disease characterized by chronic inflammation, increases FM risk...
November 22, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27886849/prevalence-and-burden-of-comorbidities-in-chronic-obstructive-pulmonary-disease
#18
REVIEW
Alexandru Corlateanu, Serghei Covantev, Alexander G Mathioudakis, Victor Botnaru, Nikolaos Siafakas
The classical definition of Chronic Obstructive Pulmonary Disease (COPD) as a lung condition characterized by irreversible airway obstruction is outdated. The systemic involvement in patients with COPD, as well as the interactions between COPD and its comorbidities, justify the description of chronic systemic inflammatory syndrome. The pathogenesis of COPD is closely linked with aging, as well as with cardiovascular, endocrine, musculoskeletal, renal, and gastrointestinal pathologies, decreasing the quality of life of patients with COPD and, furthermore, complicating the management of the disease...
November 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27886206/the-antidepressant-like-activity-of-ac-5216-a-ligand-for-18kda-translocator-protein-tspo-in-an-animal-model-of-diabetes-mellitus
#19
Zhi-Kun Qiu, Jia-Li He, Xu Liu, Guan-Hua Zhang, Jia Zeng, Hong Nie, Yong-Gang Shen, Ji-Sheng Chen
Diabetes mellitus is a chronic disease that is associated with depression. Also, depression is common in adults with type 2 diabetes mellitus (T2DM). Translocator protein (18kDa) (TSPO) and allopregnanolone play an important role in the depression treatment. However, few studies have evaluated TSPO and allopregnanolone in the treatment of depression in T2DM. AC-5216, a ligand for TSPO, produces anxiolytic- and antidepressant-like effects in animal models. The present study aimed to explore antidepressant-like effects of AC-5216 on diabetic rats...
November 25, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27884375/the-inflammasome-friend-or-foe-in-chlamydia-infection
#20
EDITORIAL
Emma Louise Walton
In this issue of the Biomedical Journal, we take a look at the still somewhat perplexing role of the inflammasome in Chlamydia infection. We also highlight findings suggesting a link between structural changes to arteries in the brain and the onset of depression. Finally, we learn about some of the implications of co-morbidity between diabetes and infectious diseases.
October 2016: Biomedical Journal
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