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JOURNAL ARTICLE
Daphne van Wees, Liza Coyer, Mark van den Elshout, Eline Op de Coul, Fleur van Aar
Pre-exposure prophylaxis (PrEP) use prevents HIV transmission, and may lead to changes in sexual behavior. We aimed to explore sexual behavior over time, and identify predictors of behavior change in men who have sex with men (MSM) using PrEP at sexual health centers (SHC) in the Netherlands. We used longitudinal data from the national STI surveillance database (January 2018-June 2021) of HIV-negative MSM who first initiated PrEP in the national PrEP pilot. We modelled behavior change after PrEP initiation, and identified predictors of behavior change using multi-state Markov models...
May 6, 2024: Archives of Sexual Behavior
#22
JOURNAL ARTICLE
Lisbeth Mølgaard Laustsen, Linda Ejlskov, Danni Chen, Mathias Lasgaard, Jaimie L Gradus, Søren Dinesen Østergaard, Marie Stjerne Grønkjær, Oleguer Plana-Ripoll
BACKGROUND: Despite the recognised importance of mental disorders and social disconnectedness for mortality, few studies have examined their co-occurrence. AIMS: To examine the interaction between mental disorders and three distinct aspects of social disconnectedness on mortality, while taking into account sex, age and characteristics of the mental disorder. METHOD: This cohort study included participants from the Danish National Health Survey in 2013 and 2017 who were followed until 2021...
May 6, 2024: British Journal of Psychiatry
#23
JOURNAL ARTICLE
Masataka Ota, Takayuki Okumo, Atsushi Sato, Reo Nagasaka, Marika Mukunoki, Kanako Izukashi, Jun Oike, Saki Yagura, Takayuki Koya, Koji Kanzaki
BACKGROUND: Knee osteoarthritis (KOA) is a chronic joint disease affecting activities of daily living (ADL) and quality of life due to pain and limited range of motion, afflicting a large number of patients worldwide. However, it is difficult to prevent the progression of the disease. Therapeutic strategies for KOA aim to maintain ADL and QOL by alleviating pain or managing locomotive function. Recently, intra-articular injection of platelet-rich plasma (PRP) has been gaining attention...
April 2024: Curēus
#24
JOURNAL ARTICLE
Chung-Ying Lin, Meng-Che Tsai, Mónika Koós, Léna Nagy, Shane W Kraus, Zsolt Demetrovics, Marc N Potenza, Rafael Ballester-Arnal, Dominik Batthyány, Sophie Bergeron, Joël Billieux, Peer Briken, Georgina Cárdenas-López, Joana Carvalho, Jesús Castro-Calvo, Lijun Chen, Giacomo Ciocca, Ornella Corazza, Rita I Csako, David P Fernandez, Elaine F Fernandez, Hironobu Fujiwara, Johannes Fuss, Roman Gabrhelík, Ateret Gewirtz-Meydan, Biljana Gjoneska, Mateusz Gola, Joshua B Grubbs, Hashim T Hashim, Md Saiful Islam, Mustafa Ismail, Martha Jiménez-Martínez, Tanja Jurin, Ondrej Kalina, Verena Klein, András Költő, Sang-Kyu Lee, Karol Lewczuk, Christine Lochner, Silvia López-Alvarado, Kateřina Lukavská, Percy Mayta-Tristán, Ion Milea, Dan J Miller, Oľga Orosová, Gábor Orosz, Fernando P Ponce, Gonzalo R Quintana, Gabriel C Quintero Garzola, Jano Ramos-Diaz, Kévin Rigaud, Ann Rousseau, Marco De Tubino Scanavino, Marion K Schulmeyer, Pratap Sharan, Mami Shibata, Sheikh Shoib, Vera Sigre-Leirós, Luke Sniewski, Ognen Spasovski, Vesta Steibliene, Dan J Stein, Julian Strizek, Aleksandar Štulhofer, Berk C Ünsal, Marie-Pier Vaillancourt-Morel, Marie Claire Van Hout, Beáta Bőthe
BACKGROUND: The three-item Sexual Distress Scale (SDS-3) has been frequently used to assess distress related to sexuality in public health surveys and research on sexual wellbeing. However, its psychometric properties and measurement invariance across cultural, gender and sexual subgroups have not yet been examined. This multinational study aimed to validate the SDS-3 and test its psychometric properties, including measurement invariance across language, country, gender identity, and sexual orientation groups...
2024: International Journal of Clinical and Health Psychology: IJCHP
#25
Pati Aji Achdiat, Rita Septharina, Rasmia Rowawi, Hartati Purbo Dharmadji, Diah Puspitosari, Hermin Aminah Usman, Retno Hesty Maharani
Extragenital warts caused by HPV types 6 and 11 are rarely reported. However, major risk factors for anogenital warts (AGW) include men who have sex with men (MSM) and Human Immunodeficiency Virus (HIV) infection. The incidence of extragenital warts among these populations has not been reported. This study presented a case report of a 33-year-old male with high-risk sexual behavior who showed symptoms of flesh-colored and hyperpigmentation papules. Furthermore, verrucous surfaces were observed at genital and extragenital...
2024: HIV/AIDS: Research and Palliative Care
#26
JOURNAL ARTICLE
Aline Marileen Wiegersma, Amber Boots, Emma F van Bussel, Birgit I Lissenberg, Mark M J Nielen, Tessa J Roseboom, Susanne R de Rooij
BACKGROUND: A poor prenatal environment adversely affects brain development. Studies investigating long-term consequences of prenatal exposure to the 1944-45 Dutch famine have shown that those exposed to famine in early gestation had poorer selective attention, smaller brain volumes, poorer brain perfusion, older appearing brains, and increased reporting of cognitive problems, all indicative of increased dementia risk. OBJECTIVE: In the current population-based study, we investigated whether dementia incidence up to age 75 was higher among individuals who had been prenatally exposed to famine...
May 3, 2024: Current Alzheimer Research
#27
JOURNAL ARTICLE
Sheeba Santhini Manoharan-Basil, Zina Gestels, Saïd Abdelatti, Irith De Baetselier, Thibaut Vanbaelen, Armin Hinterwirth, Thuy Doan, Thomas Lietman, Chris Kenyon
BACKGROUND AND OBJECTIVES: Antimicrobial resistance poses a considerable threat in high-antimicrobial-consumption populations, such as men who have sex with men (MSM) taking HIV pre-exposure prophylaxis. While the ResistAZM trial found no increase in macrolide resistance genes in MSM with gonorrhea after azithromycin treatment, the MORDOR trial observed an increase in these genes after mass azithromycin distribution. We hypothesized that this could be due to saturation of the resistome...
May 2, 2024: International Journal of Infectious Diseases: IJID
#28
JOURNAL ARTICLE
Jihye Kim, Lynne R Wilkens, Christopher A Haiman, Loïc Le Marchand, Song-Yi Park
BACKGROUND & AIMS: Plant-based dietary patterns have been associated with lower risk of cardiovascular disease (CVD), some cancers, and related mortality in U.S. POPULATIONS: However, the quality of plant foods has rarely been considered in the association between plant-based diets and mortality, especially in a population with various racial and ethnic backgrounds. We investigated whether the adherence to plant-based dietary patterns and the healthiness of plant foods are associated with mortality from all causes, CVD, and cancer and evaluated how the association varies by race and ethnicity...
April 29, 2024: Clinical Nutrition
#29
JOURNAL ARTICLE
Yuhang Qian, Roger Detels, Warren Scott Comulada, Marco A Hidalgo, Sung-Jae Lee, Katie B Biello, Elizabeth A Yonko, M Reuel Friedman, Frank J Palella, Michael W Plankey, Matthew J Mimiaga
Men who have sex with men (MSM) are at increased risk for certain types of chronic diseases and mental health problems. Despite having extended survival in the highly active antiretroviral therapy (HAART) era, MSM living with HIV contend with aging-related diseases and complications with treatment. Consequent hospitalizations incur high costs, fear, low quality of life, and frailty. Unlike heterosexual men, MSM experience more structural violence and "syndemics" of psychosocial factors that not only accelerate HIV acquisition and transmission risk but also may increase morbidity, leading to greater rates of hospitalization...
May 4, 2024: AIDS and Behavior
#30
JOURNAL ARTICLE
Jianan Zheng, Zhihui Hou, Weihua Yin, Yang Gao, Yanan Ma, Bin Lu
BACKGROUND: The 2019 European Society of Cardiology (ESC) guidelines proposed a pre-test probability (PTP) model to determine the likelihood of coronary artery disease (CAD). However, the prediction accuracy of this model has not yet been evaluated in Chinese populations. This study aimed to validate the 2019 ESC-PTP model in predicting CAD using coronary computed tomography angiography (CCTA) outcomes in a Chinese population. METHODS: A total of 26,346 consecutive patients with suspected CAD who underwent CCTA were included...
May 2, 2024: Journal of Cardiovascular Computed Tomography
#31
JOURNAL ARTICLE
Peter A Newman, Venkatesan Chakrapani, Notisha Massaquoi, Charmaine C Williams, Wangari Tharao, Suchon Tepjan, Surachet Roungprakhon, Joelleann Forbes, Sarah Sebastian, Pakorn Akkakanjanasupar, Muna Aden
PURPOSE: Sexual and gender minority and racialized populations experienced heightened vulnerability during the Covid-19 pandemic. Marginalization due to structural homophobia, transphobia and racism, and resulting adverse social determinants of health that contribute to health disparities among these populations, were exacerbated by the Covid-19 pandemic and public health measures to control it. We developed and tested a tailored online intervention (#SafeHandsSafeHearts) to support racialized lesbian, gay, bisexual, transgender, queer, and other persons outside of heteronormative and cisgender identities (LGBTQ+) in Toronto, Canada during the pandemic...
2024: PloS One
#32
JOURNAL ARTICLE
Wenhua Lu, Thinh Toan Vu, Leo Wilton, Mark Paige, Vijay Nandi, Emily Greene, Victoria Frye
Alcohol misuse is a significant health concern among gay, bisexual, same-gender-loving, and other men who have sex with men (MSM). Yet, little is known about the severity and predictors of alcohol misuse among self-reported young Black MSM. This study aimed to identify patterns of and factors associated with alcohol misuse in a sample of young Black MSM living in New York City. Baseline data from a randomized controlled trial aimed at improving the uptake of HIV testing among 250 MSM aged 18 to 29 were analyzed...
2024: American Journal of Men's Health
#33
JOURNAL ARTICLE
Silvi Shah, Annette L Christianson, Karthikeyan Meganathan, Anthony C Leonard, Deidra C Crews, Jack Rubinstein, Mark M Mitsnefes, Daniel P Schauer, Charuhas V Thakar
BACKGROUND: Cardiovascular disease is the leading cause of mortality in patients with kidney failure, and their risk of cardiovascular events is 10 to 20 times higher as compared with the general population. METHODS AND RESULTS: We evaluated 508 822 patients who initiated dialysis between January 1, 2005 and December 31, 2014 using the United States Renal Data System with linked Medicare claims. We determined hospitalization rates for cardiovascular events, defined by acute coronary syndrome, heart failure, and stroke...
May 3, 2024: Journal of the American Heart Association
#34
Charles Langelier, Victoria Chu, Abigail Glascock, Deborah Donnell, Cole Grabow, Clare Brown, Ryan Ward, Christina Love, Katrina Kalantar, Stephanie Cohen, Chase Cannon, Michael Woodworth, Colleen Kelley, Connie Celum, Anne Luetkemeyer
Doxycycline post-exposure prophylaxis (doxy-PEP) reduces bacterial sexually transmitted infections (STIs) among men who have sex with men and transgender women. While poised for widespread clinical implementation, the impact of doxy-PEP on antimicrobial resistance remains a primary concern as its effects on the gut microbiome and resistome, or the antimicrobial resistance genes (ARGs) present in the gut microbiome, are unknown. To investigate these effects, we studied participants from a randomized clinical trial who either received doxy-PEP as a one-time doxycycline 200 mg taken after condomless sex (DP arm, n = 100) or standard of care treatment (SOC arm, n = 50)...
April 17, 2024: Research Square
#35
JOURNAL ARTICLE
Octavious Smiley, Till Hoffmann, Jukka-Pekka Onnela
Network models are increasingly used to study infectious disease spread. Exponential Random Graph models have a history in this area, with scalable inference methods now available. An alternative approach uses mechanistic network models. Mechanistic network models directly capture individual behaviors, making them suitable for studying sexually transmitted diseases. Combining mechanistic models with Approximate Bayesian Computation allows flexible modeling using domain-specific interaction rules among agents, avoiding network model oversimplifications...
2024: Applied Network Science
#36
JOURNAL ARTICLE
Deniz Borcak, Yusuf Emre Özdemir, Yeşilyurt Zuhal, Esra Ensaroğlu, Samiha Akkaya, Kadriye Kart Yaşar
INTRODUCTION: Mpox virus is an orthopoxvirus that causes the zoonotic infectious disease known as mpox. The disease can also spread from humans to humans. It can be transmitted through contact with bodily fluids, lesions on the skin, or internal mucosal surfaces. METHOD: The number of mpox cases increased during the COVID-19 pandemic. Early diagnosis and prompt management of mpox are critical in people living with HIV (PLHIV). In this study, a cross-sectional survey was conducted among PLHIV followed at the outpatient clinic between 20 April-20 August 2023...
May 2, 2024: Current HIV Research
#37
JOURNAL ARTICLE
Yutaro Yamamoto, Ren Matsuba, Tomoyuki Nagasaka, Sachi Shimizu, Kensuke Sakai, Masakatsu Sone, Takuyuki Katabami
OBJECTIVE: To identify patients with type 2 diabetes mellitus (T2DM) with no history of fracture or osteoporosis treatment who are at risk of bone complications through the assessment of bone quality and quantity. METHODS: Of the outpatients attending our clinic during 2021 to 2022, we retrospectively enrolled 137 (men/women: 85/52, median age: 65 years) consecutive patients aged ≥40 years who had T2DM but no history of fracture or osteoporosis treatment...
May 2024: Journal of International Medical Research
#38
JOURNAL ARTICLE
Jiali Cai, Marleen Vonder, Yihui Du, Gert Jan Pelgrim, Mieneke Rook, Gerdien Kramer, Harry J M Groen, Rozemarijn Vliegenthart, Geertruida H de Bock
BACKGROUND: This population-based study aimed to identify the risk factors for lung nodules in a Western European general population. METHODS: We quantified the presence or absence of lung nodules among 12 055 participants of the Dutch population-based ImaLife (Imaging in Lifelines) study (≥45 years) who underwent low-dose chest computed tomography. Outcomes included the presence of 1) at least one solid lung nodule (volume≥30 mm3 ) and 2) a clinically relevant lung nodule (volume≥100 mm3 )...
May 2, 2024: European Respiratory Journal
#39
JOURNAL ARTICLE
Supanat Thitipatarakorn, Nipat Teeratakulpisarn, Siriporn Nonenoy, Aphakan Klinsukontakul, Sujittra Suriwong, Jirat Makphol, Piranun Hongchookiat, Thanyapat Chaya-Ananchot, Napasawan Chinlaertworasiri, Pravit Mingkwanrungruang, Carlo Sacdalan, Kultida Poltavee, Tippawan Pankam, Stephen J Kerr, Reshmie Ramautarsing, Donn Colby, Nittaya Phanuphak
INTRODUCTION: Men who have sex with men (MSM), especially those living with HIV, are at an increased risk of anal cancer. The prevalence and incidence of its precursor, anal high-grade squamous intraepithelial lesions (HSILs), among MSM who started antiretroviral therapy during acute HIV acquisition are yet to be explored. METHODS: Participants in an acute HIV acquisition cohort in Bangkok, Thailand, who agreed to take part in this study, were enrolled. All participants were diagnosed and started antiretroviral therapy during acute HIV acquisition...
May 2024: Journal of the International AIDS Society
#40
JOURNAL ARTICLE
Huei-Jiuan Wu, Sophy TingFang Shih, Tanya L Applegate, Jisoo A Kwon, Evan B Cunningham, Jason Grebely, Richard T Gray
INTRODUCTION: Simplified hepatitis C virus (HCV) diagnostic strategies have the potential to improve HCV diagnoses and treatment. We aimed to investigate the impact of simplified HCV diagnostic strategies on HCV incidence and its effect on HCV diagnosis and treatment among men who have sex with men (MSM) regardless of HIV status and use of HIV pre-exposure prophylaxis (PrEP) in Taiwan. METHODS: A compartmental deterministic model was developed to describe the natural history of HCV disease progression, the HCV care cascade and the HIV status and PrEP using among MSM...
May 2024: Journal of the International AIDS Society
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