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https://www.readbyqxmd.com/read/28330081/emerging-cam-ziziphus-nummularia-with-in-vivo-sedative-hypnotic-antipyretic-and-analgesic-attributes
#1
Abdur Rauf, Jawad Ali, Haroon Khan, Mohammad S Mubarak, Seema Patel
Ziziphus nummularia from Rhamnaceae family is traditionally used for sedative-hypnotic, antipyretic and analgesic purposes; however, scientific validations are lacking. This in vivo study was undertaken to verify the above ameliorative properties of Z. nummularia root methanolic extract. Various fractions of the extract were assayed on Balb/c mice by open field, Brewer's yeast-induced hyperthermia and acetic acid-induced writhing experiments. The significance of the outcomes was analyzed with statistical tests...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28284565/isolation-and-structure-elucidation-of-cyclopeptide-alkaloids-from-ziziphus-nummularia-and-ziziphus-spina-christi-by-hplc-dad-ms-and-hplc-pda-hrms-spe-nmr
#2
Emmy Tuenter, Kenn Foubert, Dan Staerk, Sandra Apers, Luc Pieters
Seven cyclopeptide alkaloids were isolated from the stem bark of Ziziphus nummularia and Ziziphus spina-christi. Three previously undescribed compounds were identified: nummularine-U, spinanine-B and spinanine-C, together with the known compounds mauritine-F, nummularine-D, nummularine-E and amphibine-D. For their purification either semi-preparative HPLC with DAD and ESIMS detection or HPLC-PDA-(HRMS)-SPE-NMR was applied, together with conventional separation methods. Their structures were elucidated by spectroscopic means...
March 8, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28282293/preliminary-phytochemical-analysis-and-evaluation-of-antioxidant-cytotoxic-and-inhibition-of-lipopolysaccaride-induced-nos-inos-expression-in-balb-c-mice-liver-by-ziziphus-oenoplia-mill-fruit
#3
Ramaraj Thirugnanasampandan, Gunasekar Ramya, Gunasekaran Bhuvaneswari, Srinivasan Aravindh, Suresh Vaishnavi, Madhusudhanan Gogulramnath
BACKGROUND: Ziziphus oenoplia Mill. is an ethnomedicinal plant and its fruit has been traditionally used by Puliar tribes of Anamalai Hills, Tamil Nadu, India to treat various ailments. Phytochemical analysis, antioxidant, cytotoxic and inducible nitric oxide synthase (iNOS) gene downregulation activities of Z. oenoplia fruit (ZOF) were studied. METHODS: To explore bioactive compounds present in the ripened fruits, high-performance thin-layer chromatography (HPTLC) and gas chromatography/mass spectrometry (GC-MS) analysis were done...
March 10, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28274571/dammarane-type-saponins-from-leaves-of-ziziphus-spina-christi
#4
Alen Bozicevic, Maria De Mieri, Angela Di Benedetto, Matthias Hamburger
Phytochemical profiling of Ziziphus spina-christi leaves led to the characterization of 10 dammarane-type saponins and 12 phenolic compounds. Isolation was achieved by gel chromatography on Sephadex LH20, open column chromatography on silica gel, and semi-preparative HPLC with PDA and ELSD detectors. Structural characterization was performed by extensive 1D and 2D NMR, mass spectrometry, and by GC-MS of sugar derivatives. A biosynthetic pathway leading to three previously undescribed sapogenins is proposed...
March 5, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28274443/isolation-structures-and-bioactivities-of-the-polysaccharides-from-jujube-fruit-ziziphus-jujuba-mill-a-review
#5
REVIEW
Xiaolong Ji, Qiang Peng, Yuepeng Yuan, Jing Shen, Xueying Xie, Min Wang
Jujube (Ziziphus Jujuba Mill.) has been eaten as a fruit and nutraceutical food in China for thousands of years. Recent phytochemical and pharmacological studies have shown that the polysaccharides are one of major biologically active components of the jujube fruit and have various biological effects, including immunomodulatory, antioxidant, antitumor, hepatoprotective, and hypoglycemic activities, and gastrointestinal-protective effects. Although the extraction and purification of jujube polysaccharides are tedious processes, including different steps of liquid- and solid-phase separation, the polysaccharides have been structurally characterized...
July 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28271568/effect-of-ziziphus-jujube-fruit-infusion-on-lipid-profiles-glycaemic-index-and-antioxidant-status-in-type-2-diabetic-patients-a-randomized-controlled-clinical-trial
#6
Zeinab Yazdanpanah, Akram Ghadiri-Anari, Alireza Vahidi Mehrjardi, Ali Dehghani, Hadi Zare Zardini, Azadeh Nadjarzadeh
This study was designed to assess the effects of Ziziphus jujube fruit (ZJF) infusion on lipid profiles, glycaemic control and antioxidant status in patients with type 2 diabetes mellitus (T2DM). In this randomized controlled clinical trial, 116 participants with T2DM (older than 30 years) were assigned to consume a balanced diet or diet plus ZJF infusion (10 g/100 mL boiling water) three times/day before main meals for 12 weeks. Diet was designed to be energy restricted (500 kcal/day deficit from estimated energy requirements), and macronutrient content was similar in both groups (55% carbohydrate, 15% protein and 30% fat)...
March 7, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28251407/jujube-ziziphus-jujuba-mill-fruit-feeding-extends-lifespan-and-increases-tolerance-to-environmental-stresses-by-regulating-aging-associated-gene-expression-in-drosophila
#7
Saurav Ghimire, Man Su Kim
Jujube (Ziziphus Jujuba Mill.) fruit has been utilized as an adjunct to alleviate medical symptoms including, but not limited to, anorexia, fatigue, anxiety and mild diarrhea for centuries. Despite a growing body of literature revealing jujube fruit's health promoting properties such as anti-cancer, anti-inflammation and anti-oxidant effects (shown with cell-based in vitro platforms), there is a paucity of studies systemically examining its impact on whole organisms or throughout the entire course of life utilizing in vivo model systems...
March 1, 2017: Biogerontology
https://www.readbyqxmd.com/read/28140658/characterization-antifungal-and-cytotoxic-evaluation-of-green-synthesized-zinc-oxide-nanoparticles-using-ziziphus-nummularia-leaf-extract
#8
Hemali Padalia, Sumitra Chanda
Zinc oxide nanoparticles (ZnO NPs) were synthesized using Ziziphus nummularia leaf extract. The characterization was done by various spectral analysis and antifungal (anti-candidal) activity against multidrug resistant clinical isolates and their cytotoxic potential was evaluated. The ZnO NPs were 17.33 nm in size and were spherical/irregular in shape. The antifungal activity of ZnO NPs was better than four standard azole antibiotics and they also showed potent cytotoxic effect against HeLa cancer cell line...
January 31, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28124048/hepatoprotective-standardized-etoh-water-extract-of-the-leaves-of-ziziphus-jujuba
#9
Lu Bai, Xueqin Cui, Ni Cheng, Wei Cao, Yong Wu, Sen Guo, Li Zhang, Chi-Tang Ho, Naisheng Bai
The hepatoprotective activity of the EtOH-water extract of Ziziphus jujuba leaves was evaluated against CCl4-induced hepatic damage in mice. The EtOH-water extract significantly alleviated liver damage as indicated by the decreased levels of serum ALT and AST and the decreased MDA content, the increased levels of SOD, GSH and GSH-Px, and the reduced pathological tissue injury induced by CCl4. A quantitative analysis of fifteen major constituents (1-15) of the EtOH-water extract of the leaves of Z. jujuba was conducted by HPLC-DAD...
January 26, 2017: Food & Function
https://www.readbyqxmd.com/read/28101436/development-and-characterization-of-microsatellite-primers-in-the-endangered-mediterranean-shrub-ziziphus-lotus-rhamnaceae
#10
Ana González-Robles, Antonio J Manzaneda, Jesús M Bastida, Nick Harvey, Rafael Jaime, Teresa Salido, Luisa M Martínez, Ana Fernández-Ocaña, Julio M Alcántara, Pedro J Rey
PREMISE OF THE STUDY: Microsatellite primers were developed to characterize and evaluate patterns of genetic diversity and structure in the endangered Mediterranean shrub Ziziphus lotus (Rhamnaceae). METHODS AND RESULTS: Twenty microsatellite primers were developed for Z. lotus, of which 14 were polymorphic. We evaluated microsatellite polymorphism in 97 specimens from 18 Spanish and seven Moroccan populations. Between two and eight alleles were found per locus, and the average number of alleles was 5...
December 2016: Applications in Plant Sciences
https://www.readbyqxmd.com/read/28053589/nectar-secretion-dynamics-and-honey-production-potentials-of-some-major-honey-plants-in-saudi-arabia
#11
Nuru Adgaba, Ahmed Al-Ghamdi, Yilma Tadesse, Awraris Getachew, Awad M Awad, Mohammad J Ansari, Ayman A Owayss, Seif Eldin A Mohammed, Abdulaziz S Alqarni
The contribution of a bee plant species to honey production depends on the plant's nectar secretion quality and quantity, which is mainly governed by biotic and abiotic factors. The aim of the current study, was to investigate the nectar secretion dynamics and honey production potential of 14 major bee plant species of the target area. We examined the quantity and dynamics of nectar sugar per flower five times a day using a nectar sugar washing technique and direct measuring of nectar with calibrated capillary tubes...
January 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28005948/the-jujube-genome-provides-insights-into-genome-evolution-and-the-domestication-of-sweetness-acidity-taste-in-fruit-trees
#12
Jian Huang, Chunmei Zhang, Xing Zhao, Zhangjun Fei, KangKang Wan, Zhong Zhang, Xiaoming Pang, Xiao Yin, Yang Bai, Xiaoqing Sun, Lizhi Gao, Ruiqiang Li, Jinbo Zhang, Xingang Li
Jujube (Ziziphus jujuba Mill.) belongs to the Rhamnaceae family and is a popular fruit tree species with immense economic and nutritional value. Here, we report a draft genome of the dry jujube cultivar 'Junzao' and the genome resequencing of 31 geographically diverse accessions of cultivated and wild jujubes (Ziziphus jujuba var. spinosa). Comparative analysis revealed that the genome of 'Dongzao', a fresh jujube, was ~86.5 Mb larger than that of the 'Junzao', partially due to the recent insertions of transposable elements in the 'Dongzao' genome...
December 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27976350/antiplasmodial-activity-of-cyclopeptide-alkaloids-from-hymenocardia-acida-and-ziziphus-oxyphylla
#13
E Tuenter, V Exarchou, R Ahmad, A Baldé, P Cos, L Maes, S Apers, L Pieters
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27975414/development-and-application-of-uhplc-pda-qtof-ms-based-dereplication-strategy-for-the-discovery-of-cytotoxic-ceanothane-and-lupane-type-triterpenoids-from-the-roots-of-ziziphus-jujuba
#14
https://www.readbyqxmd.com/read/27957735/residue-analysis-and-risk-assessment-of-tebuconazole-in-jujube-ziziphus-jujuba-mill
#15
Xiangwei You, Yiqiang Li, Xiuguo Wang, Jinli Xu, Xiao Zheng, Chengchen Sui
In this study, a sensitive and reliable analytical method, based on a modified Quick, Easy, Cheap, Effective, Rugged and Safe procedure, was established for determination of tebuconazole in jujube. After extraction with acetonitrile, the samples were cleaned up by dispersive solid-phase extraction with primary secondary amine, and determined by high-performance liquid chromatography tandem mass spectrometry. At fortification levels of 0.01, 0.1 and 2.0 mg kg(-1) , the average recoveries of tebuconazole in jujube were in the range 97...
December 13, 2016: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/27937039/effects-of-butanol-fraction-of-ziziphus-mucronata-root-ethanol-extract-on-glucose-homeostasis-serum-insulin-and-other-diabetes-related-parameters-in-a-murine-model-for-type-2-diabetes
#16
Mohammed Auwal Ibrahim, Md Shahidul Islam
CONTEXT: Ziziphus mucronata Willd (Rhamnaceae) is currently used in Nigerian traditional treatment of diabetes mellitus. However, detailed information on the antidiabetic potential of the plant parts is presently unknown. OBJECTIVES: The present study investigated the antidiabetic effects of the butanol fraction of Z. mucronata root (ZMBF) in a type 2 diabetes (T2D) model of rats. MATERIALS AND METHODS: T2D was induced in rats by feeding a 10% fructose solution ad libitum for two weeks followed by an intraperitoneal injection of streptozotocin (40 mg/kg bw) and the animals were orally treated with ZMBF 150 or 300 mg/kg bw for five days a week for four weeks...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27936885/assessment-of-ziziphus-mauritiana-grown-on-fly-ash-dumps-prospects-for-phytoremediation-but-concerns-with-the-use-of-edible-fruit
#17
Vimal Chandra Pandey, Tripti Mishra
A field study was carried out on fly ash dumps of Panki Thermal Power Station to assess the phytoaccumulation of elements in various plant parts of edible fruit tree Ziziphus mauritiana. Out of the twelve analysed elements, the highest concentration was found for Fe followed by Mn > Se > Zn > Mo > Cu > Cr > Pb > Cd >Ni > As > Co in rhizospheric substrate of Z. mauritiana grown on fly ash dumps. Metal accumulation, bioconcentration factor and translocation factor for each metal was calculated in various parts of the edible fruit tree...
December 12, 2016: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/27933893/isolation-and-structure-elucidation-by-lc-dad-ms-and-lc-dad-spe-nmr-of-cyclopeptide-alkaloids-from-the-roots-of-ziziphus-oxyphylla-and-evaluation-of-their-antiplasmodial-activity
#18
Emmy Tuenter, Rizwan Ahmad, Kenn Foubert, Adnan Amin, Maria Orfanoudaki, Paul Cos, Louis Maes, Sandra Apers, Luc Pieters, Vassiliki Exarchou
Nine cyclopeptide alkaloids (1-9), of which five (compounds 2, 3, 5, 8, and 9) are described herein for the first time, were isolated from roots of Ziziphus oxyphylla by means of conventional separation methods as well as semipreparative HPLC with DAD and ESIMS detection and LC-DAD-SPE-NMR. Structure elucidation was done by spectroscopic means. Nummularine-R (1), a previously known constituent from this species, was isolated along with its new derivatives O-desmethylnummularine-R (2) and O-desmethylnummularine-R N-oxide (3)...
November 23, 2016: Journal of Natural Products
https://www.readbyqxmd.com/read/27824938/genome-wide-identification-and-analysis-of-micrornas-involved-in-witches-broom-phytoplasma-response-in-ziziphus-jujuba
#19
Fenjuan Shao, Qian Zhang, Hongwei Liu, Shanfa Lu, Deyou Qiu
MicroRNAs (miRNAs) play an important role in responding to biotic and abiotic stresses in plants. Jujube witches'-broom a phytoplasma disease of Ziziphus jujuba is prevalent in China and is a serious problem to the industry. However, the molecular mechanism of the disease is poorly understood. In this study, genome-wide identification and analysis of microRNAs in response to witches'-broom was performed. A total of 85 conserved miRNA unique sequences belonging to 32 miRNA families and 24 novel miRNA unique sequences, including their complementary miRNA* strands were identified from small RNA libraries derived from a uninfected and witches'-broom infected Z...
2016: PloS One
https://www.readbyqxmd.com/read/27649580/two-new-c-glucosyl-flavonoids-from-ziziphus-jujube-and-their-anti-inflammatory-activity
#20
Qiang Fu, Yu Ma, Jiang Chen, Hai-Mei Yuan, Yu-Zhong Zheng
Two new C-glucosyl flavonoids 6''-O-feruloylspinosin and 6''-O-feruloyl-6'''-p-hydroxybenzoylspinosin, together with five known compounds, were isolated from the seeds of Ziziphus jujube (Rhamnaceae family). Their structures were elucidated on the basis of chemical and spectroscopic evidences. Compounds 1-7 showed moderate inhibitory effects against COX-1 and COX-2 enzymes.
September 21, 2016: Journal of Asian Natural Products Research
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