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J Zhang, Y K Fan, P Wang, Q Q Chen, G Wang, A E Xu, L Q Chen, R Hu, W Chen, Z Q Song, F Hao
BACKGROUND: China has one of the largest populations with tuberculosis worldwide. Cutaneous tuberculosis (CTB) is a rare manifestation of mycobacterial infection. Although CTB is well described, it is important to periodically revisit the prevailing clinical and epidemiological features in most populated countries such as China, India, and Indonesia, where tuberculosis is still a major health problem. OBJECTIVE: This retrospective study aimed to re-evaluate the CTB cases in China in the past 50 years to obtain a comprehensive insight into this multiplex entity...
April 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Adama Dicko, Ousmane Faye, Youssouf Fofana, Moussa Soumoutera, Siritio Berthé, Saidou Touré, Bekaye Traoré, Binta Guindo, Koureissi Tall, Alimata Keita, Lassine Kéita, Karim Coulibaly, Somita Keita
INTRODUCTION: Tuberculosis is the most common mycobacteriosis in sub-Saharan Africa. Cutaneous tuberculosis is rare and underdiagnosed due to its clinical polymorphism and to the smallness of technical equipment. This study aims to describe the epidemiological, clinical, histopathological aspects of cutaneous tuberculosis in Bamako (Mali). METHODS: We conducted a cross-sectional descriptive study from January 1991 to December 2008. The study was performed in the Department of Dermatology at the National Center for Disease Control and in the Department of Pneumophtisiology at the Hospital of Point G...
2017: Pan African Medical Journal
Mona A Agnihotri, Kanchan S Kothari, Leena P Naik, Sharada Patil
Anaplastic large cell lymphoma (ALCL) is a T-cell lymphoma, accounting for <5% of non-Hodgkin's lymphoma. Cutaneous involvement can be primary or secondary arising in systemic ALCL. The diagnostic feature in both is the presence of pleomorphic, CD30 positive hallmark cells. We present a case of ALCL in a 19-year-old male presenting as an ulcerated scalp swelling. Clinical impression was actinomycosis or scrofuloderma. Cytology smears showed large dispersed pleomorphic cells with hyperlobated nuclei and multinucleated giant cells...
July 2017: Journal of Cytology
Debabrata Bandyopadhyay
No abstract text is available yet for this article.
March 1, 2017: Indian Journal of Dermatology, Venereology and Leprology
Ilhan Afsar, Fatma Sule Afsar
BACKGROUND AND AIM: Cutaneous tuberculosis (CTB) is still difficult to diagnose due to its varied clinical presentation and limitations of diagnostic methods. The aim of this study was to evaluate the results of diagnostic laboratory tests available for CTB. MATERIALS AND METHODS: Twenty-six skin biopsy specimens belonging to clinically suspected cases of CTB were studied retrospectively. The specimens were divided into two portions, one part processed for histopathological evaluation and the other was used for microscopy and inoculation for the isolation of mycobacteria...
July 2016: Indian Journal of Pathology & Microbiology
Karla Spelta, Lucia M Diniz
BACKGROUND: Tuberculosis is a serious health problem in Brazil so that the knowledge on the aspects of cutaneous tuberculosis is medically important. OBJECTIVE: To assess the characteristics of patients with cutaneous tuberculosis treated at the Cassiano Antonio Moraes University Hospital, located in the city of Vitória, State of Espírito Santo, Brazil. METHODS: This is a retrospective, descriptive, observational and cross-sectional study using the medical records of 29 patients with cutaneous tuberculosis treated at the Dermatology and Pulmonology services of the hospital from 1986 to 2011...
July 11, 2016: Revista do Instituto de Medicina Tropical de São Paulo
Sumit Grover, Shubhangi Vinayak Agale, Grace F D'Costa, Arvind G Valand, Vikram Kumar Gupta
INTRODUCTION: Infectious Granulomatous Dermatoses (IGDS) have various aetiological factors with a considerable overlap in the histopathological and clinical features, thus posing a diagnostic dilemma for dermatologists and pathologists. AIM: We aimed at determining the histopathological profile of IGDS correlating it with clinical features with an attempt to find the aetiology. MATERIALS AND METHODS: In a cross-sectional study conducted in a tertiary referral center of Mumbai over two years, out of 1872 skin biopsies received, 239 histopathologically diagnosed cases of IGDS were studied for histopathological features of granuloma...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
J Romaní, X Sierra, A Casson
No abstract text is available yet for this article.
October 2016: Actas Dermo-sifiliográficas
Malay Mehta, Gopikrishnan Anjaneyan, Kirti Rathod, Rita V Vora
Most common form of cutaneous tuberculosis (TB) is lupus vulgaris, which usually occurs in previously sensitized individuals who have a high degree of tuberculin sensitivity. Various forms including plaque, ulcerative, hypertrophic, vegetative, papular, and nodular forms have been described. We are reporting a case of a young female, who presented with 6 well defined erythematous scaly plaques involving both arms and a puckered scar on right forearm and right breast. Clinically, it was looking like lupus vulgaris with cold abscess, few lesions mimicking scrofuloderma, but skin biopsy from both the types of lesions revealed lupus vulgaris...
December 2015: Journal of Clinical and Diagnostic Research: JCDR
Ayumi Korekawa, Hajime Nakano, Daisuke Sawamura, Hideo Kitamura, Ken Harada
No abstract text is available yet for this article.
September 2015: European Journal of Dermatology: EJD
V Ramesh, Manas K Sen, G Sethuraman, Paschal D'Souza
This report describes 6 HIV-negative patients including 5 children with scrofuloderma and an adult with lupus vulgaris, out of a total of 303 cases of cutaneous tuberculosis seen during a 4½-year period, who showed a positive tuberculin test and granulomatous histopathology, but failed to respond to first-line antitubercular therapy. They were suspected to have multidrug-resistant infection as no other cause could be ascertained. Tissue aspirate or biopsy was sent for histopathology and culture. Mycobacterium tuberculosis was isolated from the aspirate in three patients and sputum in one with associated pulmonary tuberculosis...
July 2015: Indian Journal of Dermatology, Venereology and Leprology
Vinita Gupta
Cutaneous tuberculosis can be classified as true cutaneous tuberculosis and tuberculids which is regarded as a hypersensitivity reaction to M. tuberculosis in patients with a high degree of tuberculin sensitivity. Papulonecrotic tuberculid (PNT) is a form of tuberculid. It is an uncommon manifestation even in areas with high prevalence of tuberculosis. We report a case of 35-year-old man who presented with necrotizing papules in symmetrical fashion over the trunk and extremities for last one year along with a discharging sinus in right axilla for last two months...
February 2015: Journal of Clinical and Diagnostic Research: JCDR
Sonal Sharma, Virendra N Sehgal, Sambit N Bhattacharya, Garima Mahajan, Richa Gupta
BACKGROUND: Although cutaneous tuberculosis (CTB) is well described, it is wise to periodically revisit the prevailing clinical and epidemiological features, of this somewhat uncommon entity in developed nations that is also usually neglected in national tuberculosis control programs in countries where tuberculosis is a major health problem, to maintain heightened awareness as the HIV pandemic runs its course. METHODS: Medical records of 165 cases of CTB, diagnosed from 2007 to 2010, were studied...
June 2015: American Journal of Dermatopathology
P Bilan, C Sin, A-R Wann, M Grossin, L Courdavault, M-L Sigal, E Mahé
BACKGROUND: Tuberculosis is the most common mycobacterial disease in the world. The cutaneous form is rare in low endemic countries. The occurrence of several cutaneous tuberculosis cases in our dermatology department during 2011-2012 led us to investigate whether there was a resurgence of cutaneous tuberculosis in France. The aim was to analyse changes in cutaneous tuberculosis and the related clinical, microbiological and therapeutic data. PATIENTS AND METHODS: We conducted a retrospective study in our hospital between 2005 and 2012 by querying the PMSI database (code: A 18...
April 2015: Annales de Dermatologie et de Vénéréologie
Kumar Parimalam, G Senthil, M Vinnarasan, V Arumugakani, B M Amutha, S Lalitha, S Swarna
Atypical mycobacteria are distinct from the Mycobacterium tuberculosis. Mycobacterium chelonae, a non-pigment producing rapid grower, can be found in many cutaneous sites; infection occurs most commonly after skin trauma from surgery, injections, or minor injuries. In immune competent patients, the infection is more frequently localized as a cellulitis or a nodule, whereas, in the immunocompromised patient, dissemination (more than five lesions) can occur. Because the organism is resistant to antituberculous therapy, abscess can develop and follow a chronic, indolent course...
January 2015: Indian Dermatology Online Journal
Rajesh Kumar Reddy, Shankar Ram H S, Ashwin Pai, Muthukumar
A 47-year-old male presented with multiple perianal and gluteal pus discharging sinuses. On examination, undermined sinus edges, thick and hyperpigmented surrounding skin, sacral tenderness and a lax anal sphincter were noted. Based on clinical, radiological and histopathological evaluations, patient was diagnosed to have sacral tuberculosis with perianal and gluteal scrofuloderma and he was started on anti-tuberculosis treatment.
April 2014: Journal of Clinical and Diagnostic Research: JCDR
Ozan Haase, Alexander J von Thomsen, Detlef Zillikens, Werner Solbach, Birgit Kahle
No abstract text is available yet for this article.
August 2014: JAMA Dermatology
Chandan Kumar Das, Ashoka Mahapatra, Manasi Manaswini Das, Debasish Sahoo, Nirupama Chayani
Cutaneous tuberculosis, pulmonary tuberculosis and hanseniasis are all caused by different spp. of Mycobacterium, an intracellular pathogen whose development depends on impaired cell mediated immunity. Scrofuloderma is the most common variant of cutaneous tuberculosis, which is characterized by a direct extension of the skin which overlies the infected lymph gland, bone or joint, that breaks down to form an undermined ulcer. We are reporting a rare association of Scrofuloderma (cutaneous tuberculosis) with Hanseniasis (leprosy) in an adult male whose immune status was controversial...
February 2014: Journal of Clinical and Diagnostic Research: JCDR
Derya Uçmak, Sema Aytekin, Bilal Sula, Zeynep Meltem Akkurt, Gül Türkçü, Elif Ağaçayak
Lymphangioma circumscriptum (LC) is a benign dilation of lymph channels localized to the skin and subcutaneous tissues. It is generally localized in mouth mucosa, tongue, proximal regions of arms and legs, groin, axilla, and trunk. Primary vulvar involvement is very rare. Vulvar involvement occurs in various clinical settings. Here, two uncommon cases with giant lymphangioma circumscriptum mimicking genital warts will be presented: a 55-year-old female patient with extensive lymphangiectasic lesions and genital wart-like papular lesions in the vulva secondary to diffuse scrofuloderma scars and a 60-year-old female patient with verruca-like lesions secondary to chronic inflammation...
2013: Case Reports in Dermatological Medicine
Susmita Sahu, Satyadarshi Pattnaik, Indrani Mohanty, Moningi Venkata Narasimham, Pritilata Panda
Scrofuloderma is a common type of cutaneous tuberculosis usually manifests over an infected lymphnode, bone or joint that breaks down to form an undermined ulcer leading to discharging sinuses. We present a case of a 22 year old woman with diffuse swelling of right arm with overlying nodulo ulcerative skin lesions associated with seropurulent discharge. Routine investigations were normal and X-Ray of the right humerus showed the features of chronic osteomyelitis. Smears of the discharge for bacteria, fungi and acid fast bacilli were negative, but culture of skin biopsy showed Mycobacterium tuberculosis which was confirmed by PCR...
September 2013: Indian Journal of Dermatology
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