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https://www.readbyqxmd.com/read/28915290/lifting-the-lower-face-with-an-absorbable-polydioxanone-pdo-thread
#1
Kian Karimi, Alexandra Reivitis
Traditional rejuvenation techniques include chemical peels, rhytidectomy of the skin, laser resurfacing, injection of dermal fillers and neurotoxins, and invasive surgical procedures. Patients with brow ptosis, jowl formation, and deepening nasolabial folds currently seek antiaging procedures with no incisions and minimal downtime such as thread-lifting with barbed sutures. The present report describes a case in which polydioxanone threads were used to lift the lower third of a patient's face. Fillers were used to supplement the results achieved by the thread lift because often, when tissue has been lifted, volume deficits are revealed, which can be corrected with dermal fillers...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28904276/a-case-of-acromegaly-in-which-a-pituitary-gland-tumor-was-reduced-significantly-by-administering-octreotide-long-acting-release-lar-and-could-be-removed-surgically
#2
Tadashi Arao, Yosuke Okada, Fumi Uemura, Shigeru Nishizawa, Yoshiya Tanaka
A 54-year-old woman was admitted to our hospital for detailed examination of acromegaly because she noticed bilateral hand and finger swelling at the age of 43 and plantar thickening, facial changes and unclear articulation at the age of 49. She had prominent brow ridges, mandibular protrusion, and enlargement of the hands, feet, nasal wings, lips and tongue. Her growth hormone (GH) level was 39.8 ng/ml, insulin-like growth factor-1 (IGF-1) level was 717 ng/ml, GH level was not suppressed (22.9 ng/ml) during a 75-g oral glucose tolerance test (OGTT)...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/28887445/usb1-controls-u6-snrnp-assembly-through-evolutionarily-divergent-cyclic-phosphodiesterase-activities
#3
Allison L Didychuk, Eric J Montemayor, Tucker J Carrocci, Andrew T DeLaitsch, Stefani E Lucarelli, William M Westler, David A Brow, Aaron A Hoskins, Samuel E Butcher
U6 small nuclear ribonucleoprotein (snRNP) biogenesis is essential for spliceosome assembly, but not well understood. Here, we report structures of the U6 RNA processing enzyme Usb1 from yeast and a substrate analog bound complex from humans. Unlike the human ortholog, we show that yeast Usb1 has cyclic phosphodiesterase activity that leaves a terminal 3' phosphate which prevents overprocessing. Usb1 processing of U6 RNA dramatically alters its affinity for cognate RNA-binding proteins. We reconstitute the post-transcriptional assembly of yeast U6 snRNP in vitro, which occurs through a complex series of handoffs involving 10 proteins (Lhp1, Prp24, Usb1 and Lsm2-8) and anti-cooperative interactions between Prp24 and Lhp1...
September 8, 2017: Nature Communications
https://www.readbyqxmd.com/read/28884971/testing-the-face-shape-hypothesis-in-twins-discordant-for-nonsyndromic-orofacial-clefting
#4
Jasmien Roosenboom, Karlijne Indencleef, Greet Hens, Hilde Peeters, Kaare Christensen, Mary L Marazita, Peter Claes, Elizabeth J Leslie, Seth M Weinberg
Nonsyndromic orofacial clefts (OFCs) are complex traits characterized by multifactorial inheritance and wide phenotypic variability. Numerous studies have shown subtle differences in the faces of unaffected relatives from cleft families compared to controls, the implication being that such outward differences are an incomplete expression reflecting an underlying genetic predisposition. Twins discordant for OFCs provide a unique opportunity to further test this idea, as the unaffected co-twin shares on average 50% (for dizygotic twins) and 100% (for monozygotic twins) of the genetic risk factors as the affected twin...
September 8, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28852290/the-science-and-art-of-eyebrow-transplantation-by-follicular-unit-extraction
#5
Jyoti Gupta, Amrendra Kumar, Kavish Chouhan, C Ariganesh, Vinay Nandal
Eyebrows constitute a very important and prominent feature of the face. With growing information, eyebrow transplant has become a popular procedure. However, though it is a small area it requires a lot of precision and knowledge regarding anatomy, designing of brows, extraction and implantation technique. This article gives a comprehensive view regarding eyebrow transplant with special emphasis on follicular unit extraction technique, which has become the most popular technique.
April 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28851922/a-physics-inspired-mechanistic-model-of-migratory-movement-patterns-in-birds
#6
Christopher Revell, Marius Somveille
In this paper, we introduce a mechanistic model of migratory movement patterns in birds, inspired by ideas and methods from physics. Previous studies have shed light on the factors influencing bird migration but have mainly relied on statistical correlative analysis of tracking data. Our novel method offers a bottom up explanation of population-level migratory movement patterns. It differs from previous mechanistic models of animal migration and enables predictions of pathways and destinations from a given starting location...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28842754/chen-s-double-eyelid-fold-illusion-an-eye-size-assimilation-illusion-induced-by-a-supratarsal-fold-in-the-brow-eye-unit-a-preliminary-report
#7
Sheng-Ni Chen, Sheng-Hung Chen, Chen-Chia Chen, Chien-Lin Huang, Hao-Chih Tai, Yong-Ping Wang
BACKGROUND: Double eyelidplasty can enhance the eye size and facial attractiveness of Asian individuals with single eyelids. The authors hypothesize that a supratarsal fold can induce an eye size assimilation illusion to enhance eye dimensions and aesthetics, and seek to define the optimum vertical proportion between a supratarsal fold and the eye fissure associated with maximal induction of the size assimilation illusion. METHODS: A photometric study of the replicated photographs of ten female Taiwanese patients after double eyelidplasty was designed...
August 25, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28820280/review-of-periorbital-nerve-enlargement-and-biopsy-techniques
#8
Valerie H Chen, Brent R Hayek, Hans E Grossniklaus, Ted H Wojno, H Joon Kim
Periorbital nerve enlargement commonly indicates perineural invasion of malignancy or inflammatory conditions. This study reviews the role of supraorbital and infraorbital nerve biopsies in patients presenting with radiographic enlargement and to elucidate the surgical technique involved. A retrospective chart review (1997-2014) was performed at a single tertiary center. Patients with radiographic confirmation of enlarged supraorbital/infraorbital nerves that underwent biopsy were included. Charts were reviewed for: patient demographics and history, clinical symptoms and findings, radiographic findings, surgical method, and treatment...
August 18, 2017: Orbit
https://www.readbyqxmd.com/read/28790941/facial-contrast-is-a-cross-cultural-cue-for-perceiving-age
#9
Aurélie Porcheron, Emmanuelle Mauger, Frédérique Soppelsa, Yuli Liu, Liezhong Ge, Olivier Pascalis, Richard Russell, Frédérique Morizot
Age is a fundamental social dimension and a youthful appearance is of importance for many individuals, perhaps because it is a relevant predictor of aspects of health, facial attractiveness and general well-being. We recently showed that facial contrast-the color and luminance difference between facial features and the surrounding skin-is age-related and a cue to age perception of Caucasian women. Specifically, aspects of facial contrast decrease with age in Caucasian women, and Caucasian female faces with higher contrast look younger (Porcheron et al...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28778500/-temporal-rejuvenation
#10
A Fogli
The temporal region has imprecise limits in the young patient. During the aging process, it becomes individualized with the appearance of a temporal fossa, the temporal, orbital and zygomatic bone margins, the ptosis of the lateral part of the brow and the appearance of the wrinkles of the crow's foot. As this area frame the look, it should be taken into consideration during the clinical examination as well as the facial and cervical stages. The rejuvenation techniques are numerous, nuanced and gradual. As long as the eyebrow ptosis is not evident and the distance of the eyebrows unaltered, the volumizing techniques and the botulinum toxin can respond effectively and harmoniously to the patients' demand...
August 1, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28769552/determinative-factors-in-surgical-planning-of-eyebrow-cosmetic-and-reconstructive-surgery
#11
Mohammad Taher Rajabi, Ali Makateb, Narges Hassanpoor, Seyedeh Simindokht Hosseini, Fatameh Bazvand, Syed Ziaeddin Tabatabaie, Mohammad Bagher Rajabi
PURPOSE: The purpose of this study was to identify the different factors that an oculoplastic surgeon should consider while practicing cosmetic or reconstructive eyebrow surgery in order to have the final patient's satisfaction. SUBJECTS AND METHODS: In an observational case series study, five photographs were taken from each of 60 females to show ideal eyebrow positioning with fingers. Eyebrow landmarks, including tarsal plate show (TPS) and eyebrow height, were measured in the ideal position...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28756152/ophthalmologic-features-of-progeria
#12
Iason S Mantagos, Monica E Kleinman, Mark W Kieran, Leslie B Gordon
PURPOSE: To establish the natural history of ophthalmic characteristics in Progeria patients and to determine incidence of ocular manifestations. DESIGN: Retrospective case series of patients with Progeria who were seen between 2007 and 2016. METHODS: Setting: Tertiary-care academic center. PATIENT POPULATION: Fourteen patients (28 eyes) with Hutchinson-Gilford Progeria syndrome were included for statistical analysis from a total of 84 patients who have been enrolled in clinical trials for Progeria at Boston Children's Hospital...
July 27, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28734075/high-occurrence-of-jellyfish-predation-by-black-browed-and-campbell-albatross-identified-by-dna-metabarcoding
#13
Julie C McInnes, Rachael Alderman, Mary-Anne Lea, Ben Raymond, Bruce E Deagle, Richard A Phillips, Andrew Stanworth, David R Thompson, Paulo Catry, Henri Weimerskirch, Cristián G Suazo, Michaël Gras, Simon N Jarman
Gelatinous zooplankton are a large component of the animal biomass in all marine environments, but are considered to be uncommon in the diet of most marine top predators. However, the diets of key predator groups like seabirds have conventionally been assessed from stomach content analyses, which cannot detect most gelatinous prey. As marine top predators are used to identify changes in the overall species composition of marine ecosystems, such biases in dietary assessment may impact our detection of important ecosystem regime shifts...
July 22, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28724820/a-rare-case-of-cleft-number-nine-associated-with-atypical-cleft-number-two
#14
Shivanand Chanabasu Bubanale, Santosh B Kurbet, Linda Maria Genoveva De Piedade Sequeira
The incidence of the craniofacial cleft is rare ranging between 1.43 and 4.85/100,000 births. Tessier number nine cleft being the rarest, there are a few reports of detailed ophthalmologic examinations performed in them. In this study, 1-day-old female neonate delivered by normal vaginal delivery at term, weighing 1480 g presented with right eye dystopia, cleft extending through the lateral third of the upper eyelid, brow ending at the temporal region, conjunctival congestion, clear cornea 10 mm in diameter, normal anterior chamber, pupil 2 mm reactive to light, clear lens, and normal fundus...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28723733/hering-s-law-in-congenital-ptosis-evaluation-of-the-contralateral-response-to-unilateral-congenital-ptosis-repair
#15
Thomas J E Clark, Wesley J Klejch, Kai Wang, Richard C Allen, Jeffrey A Nerad, Keith D Carter, Erin M Shriver
PURPOSE: To determine the applicability and clinical relevance of Hering's law for the eyelids in cases of congenital ptosis. METHODS: A retrospective chart review and digital photograph analysis of patients who underwent unilateral congenital ptosis repair at a tertiary, university-based, Oculoplastics clinic was conducted. Pre- and postoperative eyelid height (marginal reflex distance), upper eyelid symmetry, and brow position were determined using ImageJ analysis software...
July 18, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28683654/efficacy-and-safety-of-multitarget-therapy-with-cyclophosphamide-and-tacrolimus-for-lupus-nephritis-a-prospective-single-arm-single-centre-open-label-pilot-study-in-japan
#16
R Sakai, T Kurasawa, E Nishi, T Kondo, Y Okada, A Shibata, K Nishimura, K Chino, A Okuyama, H Takei, H Nagasawa, K Amano
Background Pulsed cyclophosphamide or mycophenolate mofetil for lupus nephritis has limited efficacy. We previously reported a case of mixed-class IV + V lupus nephritis successfully treated with cyclophosphamide and tacrolimus. This study assessed the efficacy and safety of multitarget therapy with cyclophosphamide and tacrolimus for the treatment of lupus nephritis. Methods In a prospective, single-arm, open label pilot study, we recruited 15 patients aged 18-64 years with active lupus nephritis who met the American College of Rheumatology criteria for a diagnosis of systemic lupus erythematosus (1997)...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28666285/-endoscopic-browlift-via-endotine-forehead-device-in-patients-with-facial-palsy
#17
Laura Holtmann, Kerstin Büchsenschütz, Anja Eckstein, Anke Schlüter, Stephan Lang, Stefan Mattheis
Objective Forehead and brows form a critical aesthetic and functional subunit of the face. Chronical pPeripheral paralysis of the facial nerve or its frontal branch may cause brow ptosis and eyelid deformities with a limited field of vision and loss of facial symmetry. Techniques, especially endoscopic methods have evolved significantly. Endotine Forehead Device, an adsorbable device, is a promising tool for brow suspension. Material and Methods 9 patients underwent brow and forehead lift surgery via Endotine Forehead Device...
June 30, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28665995/transcriptomes-of-six-mutants-in-the-sen1-pathway-reveal-combinatorial-control-of-transcription-termination-across-the-saccharomyces-cerevisiae-genome
#18
Xin Chen, Kunal Poorey, Melissa N Carver, Ulrika Müller, Stefan Bekiranov, David T Auble, David A Brow
Transcriptome studies on eukaryotic cells have revealed an unexpected abundance and diversity of noncoding RNAs synthesized by RNA polymerase II (Pol II), some of which influence the expression of protein-coding genes. Yet, much less is known about biogenesis of Pol II non-coding RNA than mRNAs. In the budding yeast Saccharomyces cerevisiae, initiation of non-coding transcripts by Pol II appears to be similar to that of mRNAs, but a distinct pathway is utilized for termination of most non-coding RNAs: the Sen1-dependent or "NNS" pathway...
June 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28659977/facial-mobility-after-maxilla-mandibular-advancement-in-patients-with-severe-obstructive-sleep-apnea-syndrome-a-three-dimensional-study
#19
Laura Verzé, Francesca Antonella Bianchi, Niccolò Barla, Serena Maria Curti, Giovanni Gerbino, Guglielmo Amedeo Ramieri
Introduction. The functional results of surgery in terms of facial mobility are key elements in the treatment of patients. Little is actually known about changes in facial mobility following surgical treatment with maxillomandibular advancement (MMA). Objectives. The three-dimensional (3D) methods study of basic facial movements in typical OSAS patients treated with MMA was the topic of the present research. Materials and Methods. Ten patients affected by severe obstructive sleep apnea syndrome (OSAS) were engaged for the study...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28644071/age-invariance-in-rapid-facial-affective-reactions-to-emotionally-valenced-stimuli
#20
Matthew R Nangle, Phoebe E Bailey, Julie D Henry, Georgina S Khlentzos, Kandice J Varcin, Alexis E Whitton
It has been suggested that an age-related positivity effect may only occur in the context of explicit information processing, but it is unclear whether this bias extends to the processing of rapid facial reactions. In addition, most studies that have looked for evidence of age-related implicit positivity have used attentional (as opposed to sensory) unawareness paradigms, or used broad-based indicators of attentional awareness that do not speak to the nature of the affective response. In the present study, younger and older adults were therefore asked to view non-facial images presented supraliminally (i...
June 23, 2017: Quarterly Journal of Experimental Psychology: QJEP
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