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https://www.readbyqxmd.com/read/28334217/testosterone-effects-on-the-brain-in-transgender-men
#1
Sarah M Burke, Amir H Manzouri, Cecilia Dhejne, Karin Bergström, Stefan Arver, Jamie D Feusner, Ivanka Savic-Berglund
Transgender individuals experience incongruence between their gender identity and birth-assigned sex. The resulting gender dysphoria (GD), which some gender-incongruent individuals experience, is theorized to be a consequence of atypical cerebral sexual differentiation, but support for this assertion is inconsistent. We recently found that GD is associated with disconnected networks involved in self-referential thinking and own body perception. Here, we investigate how these networks in trans men (assigned female at birth with male gender identity) are affected by testosterone...
March 10, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28332936/ethical-concerns-about-emerging-treatment-paradigms-for-gender-dysphoria
#2
Stephen B Levin
The increasing incidence of request for medical services to support gender transition for children, adolescents and adults has consequences for society, governmental institutions, schools, families, health care professionals, and, of course, patients. The sociological momentum to recognize and accommodate to trans phenomena has posed ethical dilemmas for endocrinologists, mental health professionals and sexual specialists as they experience within themselves the clash between Respect for Patient Autonomy, Beneficence, Nonmalficience, and Informed Consent...
March 23, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28319558/effects-of-medical-interventions-on-gender-dysphoria-and-body-image-a-follow-up-study
#3
Tim C van de Grift, Els Elaut, Susanne C Cerwenka, Peggy T Cohen-Kettenis, Griet De Cuypere, Hertha Richter-Appelt, Baudewijntje P C Kreukels
OBJECTIVES: The aim of the European Network for the Investigation of Gender Incongruence is to investigate the status of all individuals who had applied for gender confirming interventions from 2007 until 2009, irrespective of whether they received treatment. The current article describes the study protocol, the effect of medical treatment on gender dysphoria and body image, and the predictive value of (pre)treatment factors on post-treatment outcomes. METHODS: Data were collected on medical interventions, transition status, gender dysphoria (Utrecht Gender Dysphoria Scale), and body image (Body Image Scale for Transsexuals)...
March 18, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28288257/military-family-physicians-readiness-for-treating-patients-with-gender-dysphoria
#4
Natasha A Schvey, Ian Blubaugh, Alexandria Morettini, David A Klein
No abstract text is available yet for this article.
March 13, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28288248/a-transgender-military-internist-s-perspective-on-readiness-for-treating-patients-with-gender-dysphoria
#5
Jamie L Henry
No abstract text is available yet for this article.
March 13, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28281883/exploring-the-association-between-eating-disorders-and-gender-dysphoria-in-youth
#6
Stephen Feder, Leanna Isserlin, Emily Seale, Nicole Hammond, Mark L Norris
This study reviews the overlap between eating disorders (EDs) and gender dysphoria (GD) in an adolescent population. A retrospective chart review was conducted on a clinical population presenting for concerns of GD. It was noted that five of the 97 patients had been found to be suffering from an ED at presentation. An additional 10 patients were noted to have ED-related symptoms. Although ED risk was elevated in trans males and females, absolute risk was higher in trans males when compared to population based prevalence rates...
March 10, 2017: Eating Disorders
https://www.readbyqxmd.com/read/28245038/kraftig-%C3%A3-kning-av-k%C3%A3-nsdysfori-bland-barn-och-unga-tidigt-insatt-behandling-ger-betydligt-b%C3%A3-ttre-prognos
#7
Louise Frisén, Olle Söder, Per-Anders Rydelius
Dramatic increase of gender dysphoria in youth In the past decade there has been a dramatic increase in the number of young people with gender dysphoria seeking help for gender-confirming medical interventions. From a situation of no more than a few patients annually, there were almost 200 referrals of gender dysphoria to the Astrid Lindgren Children's Hospital in 2016. This child and adolescent psychiatric unit has the whole country as a catchment area for patients <16 years. Gender-confirming medical interventions are regulated by a special law that sets a minimum age for legal and surgical gender reassignment to 18 years...
February 22, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28238165/challenges-in-assessing-personality-of-individuals-with-gender-dysphoria-with-the-swap-200
#8
REVIEW
V Lingiardi, G Giovanardi
BACKGROUND: Personality assessment can be useful to better understand the complexity of transgender and transsexual people. In particular, the Shedler Westen Assessment Procedure-200 (SWAP-200) is a measure that provides an accurate dimensional evaluation of personality. When assessing gender non-conforming people, however, clinicians can encounter some difficulties in giving appropriate ratings to all the items. PURPOSE OF THE REVIEW: A brief guide to the use of SWAP-200 with transgender patients is provided, taking into account three areas of psychological functioning: identity, relationships and sexuality...
February 25, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28217933/cytology-of-the-neovagina-in-transgender-women-and-individuals-with-congenital-or-acquired-absence-of-a-natural-vagina
#9
A Grosse, C Grosse, D Lenggenhager, B Bode, U Camenisch, P Bode
OBJECTIVE: The primary objective of this study was to describe the cytological findings of bowel and (penile) skin-lined neovaginas in patients with gender dysphoria (GD) and individuals with a congenital or acquired absence of a natural vagina. The secondary objective was to correlate the cytological findings with clinical characteristics such as oestrogen replacement therapy (ERT). METHODS: A retrospective review of an institutional pathology archive over a 15-year-period was performed to identify cytological samples of neovaginal vaults...
February 20, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28217493/outcome-and-preferences-in-male-to-female-subjects-with-gender-dysphoria-experience-from-eastern-india
#10
Anirban Majumder, Debmalya Sanyal
CONTEXT: Gender dysphoria (GD) is an increasingly recognized medical condition in India, and little scientific data on treatment outcomes are available. AIMS: Our objective is to study the therapeutic options including psychotherapy, hormone, and surgical treatments used for alleviating GD in male-to-female (MTF) transgender subjects in Eastern India. SUBJECTS AND METHODS: This is a retrospective study of treatment preferences and outcome in 55 MTF transgender subjects who were presented to the endocrine clinic...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28210932/personality-and-attachment-in-transsexual-adults
#11
Vittorio Lingiardi, Guido Giovanardi, Alexandro Fortunato, Valentina Nassisi, Anna Maria Speranza
The main aim of this study was to investigate the associations between personality features and attachment patterns in transsexual adults. We explored mental representations of attachment, assessed personality traits, and possible personality disorders. Forty-four individuals diagnosed with gender identity disorder (now gender dysphoria), 28 male-to-female and 16 female-to-male, were evaluated using the Shedler-Westen assessment procedure-200 (SWAP-200) to assess personality traits and disorders; the adult attachment interview was used to evaluate their attachment state-of-mind...
February 16, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28204933/a-systematic-review-of-patient-reported-outcome-measures-following-transsexual-surgery
#12
REVIEW
M Barone, A Cogliandro, N Di Stefano, V Tambone, P Persichetti
BACKGROUND: The aims of our study were to identify studies that evaluated patient satisfaction after transsexual surgery, analyze existing questionnaires, and summarize their development, psychometric properties, and content. METHODS: A systematic review of the English-language literature was performed. Patient-reported outcome measures designed to assess patient satisfaction and quality of life following transsexual surgery were identified. Qualifying instruments were assessed for content and adherence to international guidelines for development and validation...
February 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28196668/effects-of-sex-hormone-treatment-on-white-matter-microstructure-in-individuals-with-gender-dysphoria
#13
Georg S Kranz, Rene Seiger, Ulrike Kaufmann, Allan Hummer, Andreas Hahn, Sebastian Ganger, Martin Tik, Christian Windischberger, Siegfried Kasper, Rupert Lanzenberger
Sex steroid hormones such as estradiol and testosterone are known to have organizing, as well as activating effects on neural tissue in animals and humans. This study investigated the effects of transgender hormone replacement therapy on white matter microstructure using diffusion tensor imaging. Female-to-male and male-to-female transgender participants were measured at baseline, four weeks and four months past treatment start and compared to female and male controls. We observed androgenization-related reductions in mean diffusivity and increases in fractional anisotropy...
February 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28191651/the-development-of-prostate-adenocarcinoma-in-a-transgender-male-to-female-patient-could-estrogen-therapy-have-played-a-role
#14
Asma Sharif, Neha R Malhotra, Andres M Acosta, Andre A Kajdacsy-Balla, Maarten Bosland, Grace Guzman, Gail S Prins, Michael R Abern
BACKGROUND: Prostate adenocarcinoma (PCa) is a rare diagnosis in the male to female transgender (MtFT) population with only a few case reports published in the current medical literature. Long standing beliefs of androgen suppression conferring a protective effect against prostate cancer development have been challenged by the literature citing adenocarcinoma development in the prostate of rodent models following combined estrogen and testosterone treatment. MATERIALS AND METHODS: We herein present a MtFT patient who presented with high grade PCa following 20 years of exogenous estrogen therapy...
February 13, 2017: Prostate
https://www.readbyqxmd.com/read/28170299/gender-dysphoria-and-co-existing-psychosis-review-and-four-case-examples-of-successful-gender-affirmative-treatment
#15
Julia H Meijer, Guus M Eeckhout, Roy H T van Vlerken, Annelou L C de Vries
PURPOSE: Controversy exists as to if, and when, gender affirmative (GA) treatment should be offered to individuals with gender dysphoria (GD) and co-existing psychosis. Concerns exist regarding a high risk of misdiagnosing, regret afterward due to impulsive decision making, and deterioration of psychotic symptoms. This case series aims at extending the sparse literature on GA treatment in this population by identifying challenges in diagnosis and treatment and offering recommendations to overcome them...
February 7, 2017: LGBT Health
https://www.readbyqxmd.com/read/28161526/low-fertility-preservation-utilization-among-transgender-youth
#16
Leena Nahata, Amy C Tishelman, Nicole M Caltabellotta, Gwendolyn P Quinn
PURPOSE: Research demonstrates a negative psychosocial impact of infertility among otherwise healthy adults, and distress among adolescents facing the prospect of future infertility due to various medical conditions and treatments that impair reproductive health. Guidelines state that providers should counsel transgender youth about potential infertility and fertility preservation (FP) options prior to initiation of hormone therapy. The purpose of this study was to examine the rates of fertility counseling and utilization of FP among a cohort of adolescents with gender dysphoria seen at a large gender clinic...
February 1, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28161082/genital-sensory-detection-thresholds-and-patient-satisfaction-with-vaginoplasty-in-male-to-female-transgender-women
#17
Marianne LeBreton, Frédérique Courtois, Nicolas Morel Journel, Dominic Beaulieu-Prévost, Marc Bélanger, Alain Ruffion, Jean-Étienne Terrier
INTRODUCTION: Gender-affirming surgery is common for the treatment of gender dysphoria, but its effect on genital sensitivity is not well known. AIMS: To investigate genital sensory detection thresholds in male-to-female transgender women postoperatively and their relation to psychological well-being and variables of satisfaction. METHODS: Prospective study on 28 transgender women at least 18 years old operated on at least 3 months before the study by a single surgeon (N...
February 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28141788/-characteristics-of-adolescents-with-gender-dysphoria-referred-to-the-gender-identity-treatment-unit
#18
María Fernández Rodríguez, Patricia Guerra Mora, Eloya Martín Sánchez
OBJECTIVE: The demand for treatment among people with gender dys-phoria has increased during the last years. The aim of the present research was to carry out an analysis of the demand of the teenagers that requested consultation at the UTIGPA (Gender Identity Treatment Unit of Principality of Asturias) as they presented complains of gender dysphoria. METHODS: The sample included 20 minors that were treated between March 2007 and December 2015. The clinical history was made to collect informa-tion...
February 1, 2017: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/28141708/an-8-year-old-biological-female-who-identifies-herself-as-a-boy-perspectives-in-primary-care-and-from-a-parent
#19
Leah Kern, Penn Edmonds, Ellen C Perrin, Martin T Stein
An 8-year 8-month-old biological female who self-identifies as a boy, Ricardo is brought by his mother for a well-child check to his new pediatrician. Ricardo and his mother report that he is doing well, but have concerns about the upcoming changes associated with puberty. Ricardo states that he is particularly afraid of developing breasts. His mother asks about obtaining a referral to a specialist who can provide "hormone therapy" to delay puberty.Ricardo was adopted from Costa Rica at the age of 2 as a healthy girl named "Angela...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28135582/current-and-recalled-childhood-gender-identity-in-community-youth-in-comparison-to-referred-adolescents-seeking-sex-reassignment
#20
Maria Sumia, Nina Lindberg, Marja Työläjärvi, Riittakerttu Kaltiala-Heino
We studied current (GIDYQ-A) and recalled (RCGI) childhood gender identity among 719 upper secondary school students 401 girls, mean age 17.0 (SD = 0.88) years old and 318 boys, mean age 17.2 (SD = 0.86 years old in Finland. We also compared these dimensions of identity in community youth to same dimensions among adolescent sex reassignment (SR) applicants. Most community youth scored high on the normative, cis-gender end of gender experience (median score 4.9 for boys and 4.9 for girls) and recalled fairly gender typical childhood behaviours and experiences...
April 2017: Journal of Adolescence
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