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"borderline personality disorder"

Maike C Herbort, Joram Soch, Torsten Wüstenberg, Kerstin Krauel, Maia Pujara, Michael Koenigs, Jürgen Gallinat, Henrik Walter, Stefan Roepke, Björn H Schott
Patients with borderline personality disorder (BPD) frequently exhibit impulsive behavior, and self-reported impulsivity is typically higher in BPD patients when compared to healthy controls. Previous functional neuroimaging studies have suggested a link between impulsivity, the ventral striatal response to reward anticipation, and prediction errors. Here we investigated the striatal neural response to monetary gain and loss anticipation and their relationship with impulsivity in 21 female BPD patients and 23 age-matched female healthy controls using functional magnetic resonance imaging (fMRI)...
2016: NeuroImage: Clinical
Julia F Sowislo, Claudia Lange, Sebastian Euler, Henning Hachtel, Marc Walter, Stefan Borgwardt, Undine E Lang, Christian G Huber
Background There is evidence for two different types and/or sources of mental illness stigma, namely the display of psychiatric symptoms and the use of psychiatric service institutions. However, no current study has compared the two. Furthermore, gaps exist in our knowledge of both types of stigma. Little is known about the perceived stigma of specific psychiatric service treatment environments, for instance forensic settings. In addition, systematic research on stigma attached to symptoms of personality disorders in the general population is scarce, and for borderline personality disorder, nonexistent...
October 19, 2016: European Archives of Psychiatry and Clinical Neuroscience
Sophie Rausch, Julia Herzog, Janine Thome, Petra Ludäscher, Meike Müller-Engelmann, Regina Steil, Kathlen Priebe, Thomas Fydrich, Nikolaus Kleindienst
BACKGROUND: Childhood interpersonal violence is a major risk factor for developing Posttraumatic Stress Disorder (PTSD), other axis-I disorders or Borderline Personality Disorder (BPD). Individuals with a history of childhood sexual abuse (CSA) and childhood physical abuse (CPA) who meet the criteria of any axis-I disorder usually also exhibit general psychopathologic symptoms and impairments in quality of life and sexuality. The present study investigates whether women with a history of potentially traumatic CSA/CPA without any axis-I disorder or BPD show subthreshold symptoms of PTSD-specific and general psychopathology and impairments in global functioning, quality of life, and sexuality...
2016: Borderline Personality Disorder and Emotion Dysregulation
Geoffrey L Dickens, Catherine Frogley, Fiona Mason, Katina Anagnostakis, Marco M Picchioni
BACKGROUND: Clozapine is an atypical antipsychotic medicine which can cause significant side-effects. It is often prescribed off-license in severe cases of borderline personality disorder contrary to national treatment guidelines. Little is known about the experiences of those who take clozapine for borderline personality disorder. We explored the lived-experience of women in secure inpatient care who were prescribed clozapine for borderline personality disorder. FINDINGS: Adult females (N = 20) participated in audio-taped semi-structured interviews...
2016: Borderline Personality Disorder and Emotion Dysregulation
Irene Alvarez-Tomás, Joaquim Soler, Arturo Bados, Ana Martín-Blanco, Matilde Elices, Cristina Carmona, Joana Bauzà, Juan Carlos Pascual
The aim of this prospective study was to expand previously reported evidence on the 10-year clinical and functional course of borderline personality disorder (BPD) in a Spanish sample. Participants diagnosed with BPD were assessed at baseline and at 10-year follow-up to evaluate BPD symptomatology and other relevant clinical measures, suicidal behavior, dimensional personality traits, Axis I and II comorbidity, use of mental health resources, and psychosocial functioning. At the 10-year follow up, significant improvements were observed on BPD domains, suicidal behavior, and other clinical measures...
October 17, 2016: Journal of Personality Disorders
Tudor Nirestean, Emese Lukacs, Aurel Nirestean, Iosif Gabos Grecu
Borderline personality disorder is a complex disease model as it encompasses a diversity of pathological personality traits and psychopathological symptoms. It is not surprising, therefore, that it is often manifested by personality disorders across all three clusters and accompanied by other mental (Axis I) disorders. This melange makes both psychological treatment and pharmacotherapy especially challenging, and this paper describes the case of a particularly complex case of a 33-year-old Romanian patient, who has a history of severe deprivation in childhood, mood and substance use disorder in association with borderline pathology...
October 13, 2016: Personality and Mental Health
Lionel Cailhol, Margot Francois, Claire Thalamas, Cécile Garrido, Philippe Birmes, Laure Pourcel, Maryse Lapeyre-Mestre, Joel Paris
Patients with borderline personality disorder (BPD) have been shown to have increased rates of the use of medical services. The objective of this multicentre study was to compare the utilization of physical health services by patients with severe BPD (n = 36) with that of two control groups: one with other personality disorders (PDs) (n = 38) and one with matched subjects randomly selected from the general population (n = 165). Information was drawn from an insurance database collected over a 5-year period...
October 13, 2016: Personality and Mental Health
Elisabeth M P Laurenssen, Hester V Eeren, Martijn J Kikkert, Jaap Peen, Dieuwertje Westra, Jack J M Dekker, Jan J V Busschbach
BACKGROUND: Mentalization-Based Treatment (MBT) is a promising, though expensive treatment for severely ill patients with Borderline Personality Disorder (BPD). A high burden of disease in terms of quality of life (QoL) and life years lost can be a reason to prioritize mental health interventions, and specifically for BPD patients. Moreover, when the societal costs of the illness are high, spending resources on high treatment costs would be more easily legitimized. Therefore, the purpose of this study was to calculate the burden of disease of BPD patients eligible for MBT...
October 12, 2016: Health and Quality of Life Outcomes
Leo Sher, Amanda M Fisher, Caitlin H Kelliher, Justin D Penner, Marianne Goodman, Harold W Koenigsberg, Antonia S New, Larry J Siever, Erin A Hazlett
Patients with borderline personality disorder (BPD) are at high risk for suicidal behavior. However, many BPD patients do not engage in suicidal behavior. In this study, we compared clinical features of BPD patients with or without a history of suicide attempts and healthy volunteers. Compared with healthy volunteers, both BPD groups had higher Affective Lability Scale (ALS), ALS - Depression-Anxiety Subscale, Barratt Impulsivity Scale (BIS), and Lifetime History of Aggression (LHA) scores and were more likely to have a history of temper tantrums...
October 2, 2016: Psychiatry Research
Astrid Baljé, Anja Greeven, Anne van Giezen, Kees Korrelboom, Arnoud Arntz, Philip Spinhoven
BACKGROUND: Social anxiety disorder (SAD) with comorbid avoidant personality disorder (APD) has a high prevalence and is associated with serious psychosocial problems and high societal costs. When patients suffer from both SAD and APD, the Dutch multidisciplinary guidelines for personality disorders advise offering prolonged cognitive behavioral therapy (CBT). Recently there is increasing evidence for the effectiveness of schema therapy (ST) for personality disorders such as borderline personality disorder and cluster C personality disorders...
October 8, 2016: Trials
Dorina Winter
Interactions between attention and processing of emotional stimuli shed light on both sensitivity to emotional stimuli as well as emotion dysregulation. Both of the latter processes have been proposed as central characteristics of altered emotion processing in those with borderline personality disorder (BPD). This review first summarizes the conflicting behavioural, psychophysiological and neuroimaging evidence for the hypothesis that emotional dysregulation should be reflected by higher distractibility through emotional stimuli in those with BPD...
2016: Borderline Personality Disorder and Emotion Dysregulation
Kim L Gratz, Kelly E Moore, Matthew T Tull
Theory and research identify emotion dysregulation as one of the primary mechanisms underlying borderline personality disorder (BPD) and related pathology. Yet, despite the extensive research documenting an association between emotion dysregulation and BPD, many questions regarding the precise role of emotion dysregulation in the development and treatment of BPD and its associated difficulties remain unanswered. This paper reviews the extant literature on the role of emotion dysregulation in BPD and its associated difficulties, as well as the treatment of BPD-related pathology, and identifies important next steps for future research in this area...
October 2016: Personality Disorders
Carla Sharp
The aim of the Special Section that this paper contributes to is to review current trends in borderline personality disorder (BPD) research. Three major trends were identified. First, there has been a marked increase in studies that attempt to locate BPD in the dimensional latent structure of psychopathology. Second, identifying the endophenotypic markers associated with BPD has become a focus of interest. Here, we focus on one endophenotype in the form of impaired self-other processing. Third, there has been an explosion of research into the developmental aspects of BPD specifically focused on uncovering complex Biology × Environment interactions in the development of BPD...
October 2016: Personality Disorders
Sheila E Crowell, Erin A Kaufman
Over the past 2 decades there has been a dramatic shift in understanding of personality disorders, such as borderline personality disorder (BPD). What was historically viewed as an entrenched pattern of antagonistic, interpersonally dependent, and uncorrectable conduct is now seen as the outcome of complex-yet modifiable-developmental processes. The borderline label, which once inspired such harsh opprobrium in clinical communities that early diagnosis was considered taboo, is now increasingly applied to adolescents who are receiving effective treatment and desisting from a borderline trajectory...
October 2016: Personality Disorders
Stephanie D Stepp, Sophie A Lazarus, Amy L Byrd
There is an urgent need to identify signs that harbinger onset of borderline personality disorder (BPD). Advancement in this area is required to refine developmental theories, discover etiological mechanisms, improve early detection, and achieve our ultimate goal of prevention. Though many studies have supported a wide range of factors that increase subsequent risk for BPD, this literature has yet to be critically evaluated, and there are no comprehensive reviews that examine and integrate these findings. To address this limitation, we conducted a systematic review to summarize and synthesize the current literature...
October 2016: Personality Disorders
Thomas A Widiger
One of the enjoyable benefits of being an editor of a journal is the ability to develop special sections. It is evident simply from a perusal of a typical issue of Personality Disorders: Theory, Research, and Treatment (PDTRT) that a common focus of research is borderline personality disorder (BPD). BPD is among, if not the, most heavily researched personality disorder. It is only natural to have the first special section within my tenure as editor concern this personality disorder. Provided within this special section are review papers of current trends in BPD research by young (at least compared to me), leading, and innovative BPD researchers...
October 2016: Personality Disorders
Jean-Marc Guilé, Christophe Huynh, Jean-Jacques Breton, Sébastien Garny De La Rivière, Claude Berthiaume, Marie St-Georges, Réal Labelle
INTRODUCTION: Chart review is a low-cost, but highly informative, method to describe symptoms, treatment, and risk factors associated with borderline personality disorder (BPD) and to adapt screening and intervention to clinical reality. Previous chart review studies report more aggressiveness/anger and psychotic features in youths with BPD. They show that adverse family environment and parental psychopathology constitute important factors for BPD pathology. OBJECTIVES: To examine clinical characteristics of depressed BPD adolescents (12-17 years old) outpatients according to gender and to explore variables which are associated with BPD traits...
2016: Frontiers in Pediatrics
Sarah Penfold, Emily St Denis, Mir Nadeem Mazhar
BACKGROUND: Overlap of aetiological factors and demographic characteristics with clinical observations of comorbidity has been documented in fibromyalgia syndrome, chronic fatigue syndrome (CFS) and borderline personality disorder (BPD). AIMS: The purpose of this study was to assess the association of BPD with fibromyalgia syndrome and CFS. The authors reviewed literature on the prevalence of BPD in patients with fibromyalgia or CFS and vice versa. METHODS: A search of five databases yielded six eligible studies...
July 2016: BJPsych Open
Aleksandra Kupferberg, Oliver M Hager, Urs Fischbacher, Laura S Brändle, Melanie Haynes, Gregor Hasler
BACKGROUND: Price's social competition hypothesis interprets the depressive state as an unconscious, involuntary losing strategy, which enables individuals to yield and accept defeat in competitive situations. AIMS: We investigated whether patients who suffer from major depressive disorder (MDD) would avoid competition more often than either patients suffering from borderline personality disorder (BPD) or healthy controls. METHOD: In a simple paper-folding task healthy participants and patiens with MDD and BPD were matched with two opponents, one with an unknown diagnosis and one who shared their clinical diagnosis, and they had to choose either a competitive or cooperative payment scheme for task completion...
March 2016: BJPsych Open
Ales Grambal, Jan Prasko, Dana Kamaradova, Klara Latalova, Michaela Holubova, Marketa Marackova, Marie Ociskova, Milos Slepecky
INTRODUCTION: Self-stigma arises from one's acceptance of societal prejudices and is common in psychiatric patients. This investigation compares the self-stigma of a sample of patients with borderline personality disorder (BPD), schizophrenia spectrum disorder (SCH), major depressive disorder (MDD), bipolar affective disorder (BAD), and anxiety disorders (AD) and explores of the self-stigma with the subjective and objective measures of the severity of the disorder and demographic factors...
2016: Neuropsychiatric Disease and Treatment
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