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https://www.readbyqxmd.com/read/28228969/prevention-and-treatment-of-neonatal-nosocomial-infections
#1
REVIEW
Jayashree Ramasethu
Nosocomial or hospital acquired infections threaten the survival and neurodevelopmental outcomes of infants admitted to the neonatal intensive care unit, and increase cost of care. Premature infants are particularly vulnerable since they often undergo invasive procedures and are dependent on central catheters to deliver nutrition and on ventilators for respiratory support. Prevention of nosocomial infection is a critical patient safety imperative, and invariably requires a multidisciplinary approach. There are no short cuts...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28215759/impact-of-ageing-and-a-synbiotic-on-the-immune-response-to-seasonal-influenza-vaccination-a-randomised-controlled-trial
#2
Sumia Enani, Agnieszka Przemska-Kosicka, Caroline E Childs, Catherine Maidens, Honglin Dong, Lorenza Conterno, Kieran Tuohy, Susan Todd, Margot Gosney, Parveen Yaqoob
BACKGROUND & AIMS: Ageing increases risk of respiratory infections and impairs the response to influenza vaccination. Pre- and pro-biotics offer an opportunity to modulate anti-viral defenses and the response to vaccination via alteration of the gut microbiota. This study investigated the effect of a novel probiotic, Bifidobacterium longum bv. infantis CCUG 52486, combined with a prebiotic, gluco-oligosaccharide, on the B and T cell response to seasonal influenza vaccination in young and older subjects ...
January 28, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28199749/physiological-changes-of-surface-membrane-in-lactobacillus-with-prebiotics
#3
Mingfang Pan, Kishore K Kumaree, Nagendra P Shah
Synbiotics are always considered to be beneficial in healthy manipulation of gut environment; however, the purpose of this research was to investigate the dominance of synbiotic over the individual potential of probiotics and prebiotics. Four different types of prebiotics, fructo-oligosaccharides, raffinose, inulin, and cellobiose, were evaluated based on their varying degree of polymerization, combined each with 2 different Lactobacilli strains, including Lactobacillus paracasei 276 and Lactobacillus plantarum WCFS1...
February 15, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28186660/efficacy-of-a-probiotic-prebiotic-supplement-on-incidence-of-diarrhea-in-a-dog-shelter-a-randomized-double-blind-placebo-controlled-trial
#4
L Rose, J Rose, S Gosling, M Holmes
BACKGROUND: Diarrhea is the most frequent morbidity affecting kenneled dogs in animal shelters. Diarrhea impacts animal welfare and the finances of the shelter as they must treat, clean, and house affected animals until recovered. HYPOTHESIS/OBJECTIVES: Supplementing dogs entering an animal shelter with a probiotic-prebiotic, known as a synbiotic, will decrease the incidence of diarrhea. ANIMALS: Seven hundred and seventy-three dogs entering an animal shelter in the United Kingdom...
February 10, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28185614/current-status-of-the-preharvest-application-of-pro-and-prebiotics-to-farm-animals-to-enhance-the-microbial-safety-of-animal-products
#5
Rolf D Joerger, Arpeeta Ganguly
The selection of microorganisms that act as probiotics and feed additives that act as prebiotics is an ongoing research effort, but a sizable range of commercial pro-, pre- and synbiotic (combining pro- and prebiotics) products are already available and being used on farms. A survey of the composition of commercial products available in the United States revealed that Lactobacillus acidophilus, Enterococcus faecium, and Bacillus subtilis were the three most common species in probiotic products. Of the nearly 130 probiotic products (also called direct-fed microbials) for which information was available, about 50 also contained yeasts or molds...
January 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28121648/changes-in-the-gut-microbiota-after-early-administration-of-oral-synbiotics-to-young-infants-in-india
#6
Dinesh S Chandel, Maria E Perez-Munoz, Fang Yu, Robert Boissy, Radhanath Satpathy, Pravas R Misra, Nidhi Sharma, Rama Chaudhry, Sailajanandan Parida, Daniel A Peterson, Ira H Gewolb, Pinaki Panigrahi
OBJECTIVES: We examined the changes in the developing gut microbiota of Indian infants enrolled in a colonization study of an oral synbiotic (L. plantarum and fructo-oligosaccharides) preparation. METHODS: Frozen stool samples were available from a previously published clinical study of the synbiotic preparation administered daily for seven days to full term Indian infants delivered by C-section. 16S rRNA gene sequencing of fecal bacterial community-DNA was done in 11 infants sampled at Day-7 and Day-60 of life...
January 25, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28116928/assessment-of-the-synbiotic-properites-of-human-milk-oligosaccharides-and-bifidobacterium-longum-subsp-infantis-in-vitro-and-in-humanised-mice
#7
S Musilova, N Modrackova, P Hermanova, T Hudcovic, R Svejstil, V Rada, V Tejnecky, V Bunesova
The mode of delivery plays a crucial role in infant gastrointestinal tract colonisation, which in the case of caesarean section is characterised by the presence of clostridia and low bifidobacterial counts. Gut colonisation can be modified by probiotics, prebiotics or synbiotics. Human milk oligosaccharides (HMOs) are infant prebiotics that show a bifidogenic effect. Moreover, genome sequencing of Bifidobacterium longum subsp. infantis within the infant microbiome revealed adaptations for milk utilisation. This study aimed to evaluate the synbiotic effect of B...
January 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28115383/mechanistic-study-of-water-insoluble-yeast-glucans-utilization-in-bifidobacterium-breve-strain-jcm1192
#8
Hoi Yee Keung, Tsz Kai Li, Lok To Sham, Man Kit Cheung, Peter Chi Keung Cheung, Hoi Shan Kwan
: Bifidobacteria exert beneficial effects on hosts and are extensively used as probiotics. However, due to their genetic inaccessibility, little is known about their mechanism of carbohydrate utilization and regulation. Bifidobacterium breve strain JCM1192 can grow on water insoluble yeast cell wall glucans (YCWG), which are recently considered as potential prebiotics. From the result of (1)H NMR spectrometry, the YCWG were composed of highly branched (1→3)(1→6)-β-glucan and (1→4)(1→6)-α-glucan...
January 23, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28111775/effects-of-synbiotic-supplementation-on-growth-performance-carcass-characteristics-meat-quality-and-muscular-antioxidant-capacity-and-mineral-contents-in-broilers
#9
Yefei Cheng, Yueping Chen, Xiaohan Li, Weili Yang, Chao Wen, Yuru Kang, Aiqin Wang, Yanmin Zhou
BACKGROUND: The present study aimed to investigate the effects of dietary synbiotic supplementation on growth performance, carcass composition, meat quality and muscular antioxidant capacity, and mineral contents in broilers. Accordingly, 96 day-old male broiler chicks (Arbor Acres Plus; Aviagen, Huntsville, AL, USA) were randomly allocated to two groups, and each group consisted of six replicates with eight chicks each. Birds were fed a corn-soybean meal basal diet supplemented with either 0 or 1...
January 23, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28106205/synbiotic-amazonian-palm-berry-a%C3%A3-ai-euterpe-oleracea-mart-ice-cream-improved-lactobacillus-rhamnosus-gg-survival-to-simulated-gastrointestinal-stress
#10
Mayra Garcia Maia Costa, Gabriela Namur Ooki, Antônio Diogo Silva Vieira, Raquel Bedani, Susana Marta Isay Saad
The effect of açai pulp ice cream and of its supplementation with inulin (I), whey protein concentrate (WC), and/or whey protein isolate (WI) on the viability and resistance to simulated gastrointestinal stress of the probiotic Lactobacillus (Lb.) rhamnosus GG strain throughout storage at -18 °C for up to 112 days was evaluated and morphological changes during stress were monitored. Lb. rhamnosus GG viability was stable in all formulations for up to 112 days of storage, preserving populations around 9 log CFU g(-1)...
January 20, 2017: Food & Function
https://www.readbyqxmd.com/read/28088470/the-effects-of-dietary-kefir-and-low-molecular-weight-sodium-alginate-on-serum-immune-parameters-resistance-against-streptococcus-agalactiae-and-growth-performance-in-nile-tilapia-oreochromis-niloticus
#11
Hien Van Doan, Seyed Hossein Hoseinifar, Wanaporn Tapingkae, Pimporn Khamtavee
The present study evaluates the effects of dietary kefir and low molecular weight sodium alginate (LWMSA) (singular or combined) on non-specific immune response, disease resistance and growth performance of Nile tilapia (Oreochromis niloticus). Fish with average weight of 18.60 ± 0.04 g were supplied and randomly stocked in sixteen glass tanks (150 L) at density of 20 fish per tank. Fish were fed experimental diets as follows: 0 g kg(-1) LMWSA (Control, Diet 1), 10 g kg(-1) LMWSA (Diet 2), 40 g kg(-1) kefir (Diet 3), and 10 g kg(-1) LMWSA + 40 g kg(-1) kefir (Diet 4) for 50 days...
January 11, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28060791/effects-of-infant-formula-supplemented-with-prebiotics-compared-with-synbiotics-on-growth-up-to-the-age-of-12-months-a-randomized-controlled-trial
#12
Hania Szajewska, Marek Ruszczyński, Henryk Szymański, Iwona Sadowska-Krawczenko, Anna Piwowarczyk, Preben Bødstrup Rasmussen, Mette Bach Kristensen, Christina E West, Olle Hernell
BACKGROUND: Growth is an essential outcome measure for evaluating the safety of infant formulas (IF). We investigated the effects of consumption of IF supplemented with prebiotics (fructooligosaccharides, FOS, and galactooligosaccharides, GOS) compared with synbiotics (FOS/GOS and Lactobacillus paracasei ssp. paracasei strain F19) on the growth of healthy infants. METHODS: 182 full-term infants who were weaned completely from breast milk to IF at 28 days of age were randomly assigned to receive prebiotic- or synbiotic-supplemented, otherwise identical, IF until 6 months of age (intervention period)...
January 6, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28045927/synbiotics-for-broiler-chickens-in-vitro-design-and-evaluation-of-the-influence-on-host-and-selected-microbiota-populations-following-in-ovo-delivery
#13
Aleksandra Dunislawska, Anna Slawinska, Katarzyna Stadnicka, Marek Bednarczyk, Piotr Gulewicz, Damian Jozefiak, Maria Siwek
Synbiotics are synergistic combinations of prebiotics and probiotics. In chickens, synbiotics can be delivered in ovo to expedite colonization of the gut by beneficial bacteria. We therefore aimed to design synbiotics in vitro and validate them in broiler chickens upon in ovo delivery. The probiotic components of the synbiotics were Lactobacillus salivarius and Lactobacillus plantarum. Their growth was assessed in MRS medium supplemented with different prebiotics. Based on in vitro results (hatchability and growth curve), two synbiotics were designed: S1 -Lactobacillus salivarius with galactooligosaccarides (GOS) and S2 -Lactobacillus plantarum with raffinose family oligosaccharides (RFO)...
2017: PloS One
https://www.readbyqxmd.com/read/28044254/prebiotics-prosynbiotics-and-synbiotics-can-they-reduce-plasma-oxidative-stress-parameters-a-systematic-review
#14
Amin Salehi-Abargouei, Reza Ghiasvand, Mitra Hariri
This study assessed the effectiveness of presybiotics, prosybiotics and synbiotics on reducing serum oxidative stress parameters. PubMed/Medline, Ovid, Google Scholar, ISI Web of Science and SCOPUS were searched up to September 2016. English language randomized clinical trials reporting the effect of presybiotics, prosybiotics or synbiotic interventions on serum oxidative stress parameters in human adults were included. Twenty-one randomized clinical trials met the inclusion criteria for systematic review. Two studies investigated prebiotics, four studies synbiotics and fifteen studies probiotics...
January 3, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28008784/therapeutic-interventions-for-gut-dysbiosis-and-related-disorders-in-the-elderly-antibiotics-probiotics-or-faecal-microbiota-transplantation
#15
R C Vemuri, R Gundamaraju, T Shinde, R Eri
Ageing and physiological functions of the human body are inversely proportional to each other. The gut microbiota and host immune system co-evolve from infants to the elderly. Ageing is accompanied by a decline in gut microbial diversity, immunity and metabolism, which increases susceptibility to infections. Any compositional change in the gut is directly linked to gastrointestinal disorders, obesity and metabolic diseases. Increase in opportunistic pathogen invasion in the gut like Clostridium difficile leading to C...
December 23, 2016: Beneficial Microbes
https://www.readbyqxmd.com/read/28002487/long-term-transcriptomic-effects-of-prebiotics-and-synbiotics-delivered-in-ovo-in-broiler-chickens
#16
Anna Slawinska, Arkadiusz Plowiec, Maria Siwek, Marcin Jaroszewski, Marek Bednarczyk
In ovo delivery of prebiotics and synbiotics in chickens allows for the development of intestinal microflora prior to hatching, which boosts their robustness. The goal of this study was to determine the transcriptomic profile of the spleen (S), cecal tonsils (CT), and large intestine (LI) of adult chickens injected with prebiotics and synbiotics in ovo. On day 12 of embryo development, incubating eggs were injected with prebiotics: inulin alone (P1) or in combination with Lactococcus lactis subsp. lactis IBB2955 (S1), galactooligosaccharides (GOS) alone (P2) or in combination with Lactococcus lactis subsp...
2016: PloS One
https://www.readbyqxmd.com/read/27997976/the-microbiome-what-will-the-future-hold
#17
Howard Paul Monsour, Eamonn M M Quigley
Current research on the human microbiome has opened our eyes to the intimate relationship that we have with the bacteria that populate our gastrointestinal tract and its potential relationship to health and disease. To date, clinical research on the microbiome has identified intriguing associations between an altered microbiome and disease states, but proven therapeutic applications have been very limited. The ingestion of prebiotics, probiotics, and/or synbiotics is appealing to the general public and has significant commercial value, but as yet, solid evidence for clinical efficacy in liver disease has been lacking due, in large part, to the paucity of high-quality clinical trials...
September 2016: Seminars in Liver Disease
https://www.readbyqxmd.com/read/27994577/metabiotics-one-step-ahead-of-probiotics-an-insight-into-mechanisms-involved-in-anticancerous-effect-in-colorectal-cancer
#18
REVIEW
Mridul Sharma, Geeta Shukla
Colorectal cancer is closely associated with environment, diet and lifestyle. Normally it is treated with surgery, radiotherapy or chemotherapy but increasing systemic toxicity, resistance and recurrence is prompting scientists to devise new potent and safer alternate prophylactic or therapeutic strategies. Among these, probiotics, prebiotics, synbiotics, and metabiotics are being considered as the promising candidates. Metabiotics or probiotic derived factors can optimize various physiological functions of the host and offer an additional advantage to be utilized even in immunosuppressed individuals...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27989238/the-effects-of-synbiotic-supplementation-on-markers-of-insulin-metabolism-and-lipid-profiles-in-gestational-diabetes-a-randomized-double-blind-placebo-controlled-trial-corrigendum
#19
Shahnaz Ahmadi, Mehri Jamilian, Maryam Tajabadi-Ebrahimi, Parvaneh Jafari, Zatollah Asemi
No abstract text is available yet for this article.
December 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27940405/dietary-and-enteral-interventions-for-crohn-s-disease
#20
REVIEW
Takayuki Yamamoto, Takahiro Shimoyama, Moeko Kuriyama
It is now widely acknowledged that the intestinal bacterial flora together with genetic predisposing factors significantly contribute to the immunopathogenesis of inflammatory bowel disease (IBD) as reflected by mucosal immune dysregulation. Recently, there has been an increased interest in nutraceutical therapies, including probiotics, prebiotics and synbiotics. Other dietary interventions with low carbohydrate diet, omega-3 polyunsaturated fatty acids and glutamine have been attempted to downregulate the gut inflammatory response and thereby alleviate gastrointestinal symptoms...
December 8, 2016: Current Opinion in Biotechnology
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