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https://www.readbyqxmd.com/read/28504142/prebiotic-efficacy-and-mechanism-of-inulin-combined-with-inulin-degrading-lactobacillus-paracasei-i321-in-competition-with-salmonella
#1
Pochanart Kanjan, Tipparat Hongpattarakere
Inulin efficacy was proven for raising anti-Salmonella activity of the inulin-degrading Lactobacillus paracasei I321 (infant isolate) through the mechanisms of antibacterial secretion and competitive adhesion. Inulin significantly promoted competitive adhesion of L. paracasei I321 against many Gram-negative foodborne pathogenic bacteria. Salmonella Typhimurium SA2093 was completely suppressed under highly competitive niche of fecal microflora when inulin, L. paracasei I321, and their synbiotic combination were applied...
August 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28490394/synbiotic-supplementation-and-the-effects-on-clinical-and-metabolic-responses-in-patients-with-rheumatoid-arthritis-a-randomised-double-blind-placebo-controlled-trial
#2
Batol Zamani, Shima Farshbaf, Hamid R Golkar, Fereshteh Bahmani, Zatollah Asemi
Synbiotic intake may be associated with reduced inflammation in patients with rheumatoid arthritis (RA) due to optimised inflammatory markers, oxidative stress and insulin resistance. This research was conducted to assess the effects of synbiotic supplementation on the clinical and metabolic parameters of patients with RA. A total of fifty-four patients with RA were allocated into two groups to receive either a synbiotic capsule (n 27) or a placebo (n 27) for 8 weeks in this randomised, double-blind, placebo-controlled trial...
May 11, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28488210/food-additives-contaminants-and-other-minor-components-effects-on-human-gut-microbiota-a-review
#3
REVIEW
Paula Roca-Saavedra, Veronica Mendez-Vilabrille, Jose Manuel Miranda, Carolina Nebot, Alejandra Cardelle-Cobas, Carlos M Franco, Alberto Cepeda
Gut bacteria play an important role in several metabolic processes and human diseases, such as obesity and accompanying co-morbidities, such as fatty liver disease, insulin resistance/diabetes, and cardiovascular events. Among other factors, dietary patterns, probiotics, prebiotics, synbiotics, antibiotics, and non-dietary factors, such as stress, age, exercise, and climatic conditions, can dramatically impact the human gut microbiota equilibrium and diversity. However, the effect of minor food constituents, including food additives and trace contaminants, on human gut microbiota has received less attention...
May 9, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28485263/alternatives-to-antibiotics-for-maximizing-growth-performance-and-feed-efficiency-in-poultry-a-review
#4
U Gadde, W H Kim, S T Oh, Hyun S Lillehoj
With the increase in regulations regarding the use of antibiotic growth promoters and the rise in consumer demand for poultry products from 'Raised Without Antibiotics' or 'No Antibiotics Ever' flocks, the quest for alternative products or approaches has intensified in recent years. A great deal of research has focused on the development of antibiotic alternatives to maintain or improve poultry health and performance. This review describes the potential for the various alternatives available to increase animal productivity and help poultry perform to their genetic potential under existing commercial conditions...
May 9, 2017: Animal Health Research Reviews
https://www.readbyqxmd.com/read/28484432/rice-bran-and-probiotics-alter-the-porcine-large-intestine-and-serum-metabolomes-for-protection-against-human-rotavirus-diarrhea
#5
Nora Jean Nealon, Lijuan Yuan, Xingdong Yang, Elizabeth P Ryan
Human rotavirus (HRV) is a leading cause of severe childhood diarrhea, and there is limited vaccine efficacy in the developing world. Neonatal gnotobiotic pigs consuming a prophylactic synbiotic combination of probiotics and rice bran (Pro+RB) did not exhibit HRV diarrhea after challenge. Multiple immune, gut barrier protective, and anti-diarrheal mechanisms contributed to the prophylactic efficacy of Pro+RB when compared to probiotics (Pro) alone. In order to understand the molecular signature associated with diarrheal protection by Pro+RB, a global non-targeted metabolomics approach was applied to investigate the large intestinal contents and serum of neonatal gnotobiotic pigs...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28475793/effectiveness-of-probiotic-prebiotic-and-synbiotic-therapies-in-reducing-postoperative-complications-a-systematic-review-and-network-meta-analysis
#6
Nongyao Kasatpibal, JoAnne D Whitney, Surasak Saokaew, Kirati Kengkla, Margaret M Heitkemper, Anucha Apisarnthanarak
Background: Microbiome-directed therapies are increasingly used preoperatively and postoperatively to improve postoperative outcomes. Recently, the effectiveness of probiotics, prebiotics, and synbiotics in reducing postoperative complications (POCs) has been questioned. This systematic review aimed to examine and rank the effectiveness of these therapies on POCs in adult surgical patients. Methods: We searched for articles from PubMed, Embase, Cochrane, Web of Science, Scopus, and CINAHL plus...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28473897/determination-of-the-optimal-enrichment-artemia-franciscana-with-a-synbiotic-combination-of-probiotics-pediococcus-acidilactici-and-prebiotic-fructooligosaccharide
#7
(no author information available yet)
In this study the optimal amount of enriching Artemia franciscana with a synbiotic combination of Pediococcus acidilactici and fructooligosaccharide (FOS( was investigated. The experiment was conducted in a completely randomized design in ten treatments: multi-level probiotics P. acidilactici (1×10(9), 1×10(8) and 1× 10(7) CFU per L) and multi-level enriched prebiotic FOS (1, 2 and 5) g per L of solution and control. To evaluate the enrichment of adult artemia with each treatment, sampling was performed at 2, 4 and 6 hr after initiation of enrichment...
2017: Veterinary Research Forum
https://www.readbyqxmd.com/read/28471912/effect-of-synbiotic-on-the-gut-microbiota-of-caesarean-delivered-infants-a-randomized-double-blind-multicenter-study
#8
Mei Chien Chua, Kaouther Ben-Amor, Christophe Lay, Anne Goh Eng Neo, Wen Chin Chiang, Rajeshwar Rao, Charmaine Chew, Surasith Chaithongwongwatthana, Nipon Khemapech, Jan Knol, Voranush Chongsrisawat
We determined the effect of short-chain galacto-oligosaccharides (scGOS), long-chain fructo-oligosaccharides (lcFOS) and Bifidobacterium breve M-16 V on the gut microbiota of caesarean born infants. Infants were randomized to receive a standard formula (control), the same with scGOS/lcFOS and B. breve M-16 V (synbiotic), or with scGOS/lcFOS (prebiotic) from birth until week 16, 30 subjects born vaginally were included as a reference group. Synbiotic supplementation resulted in a higher bifidobacteria proportion from day 3/5 (p < 0...
May 3, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28469606/development-of-a-synbiotic-beverage-enriched-with-bifidobacteria-strains-and-fortified-with-whey-proteins
#9
Federico Baruzzi, Silvia de Candia, Laura Quintieri, Leonardo Caputo, Francesca De Leo
The objective of this study was to develop a new synbiotic beverage evaluating the ability of some bifidobacteria strains to grow in this beverage which was fortified with whey proteins up to 20 g L(-1), and enriched with 10 g L(-1) of prebiotic inulin or resistant starch. The ability of Bifidobacterium strains to survive for 30 days at 4°C was evaluated in two synbiotic whey protein fortified beverages formulated with 2% of whey proteins and 1% of inulin or resistant starch. Microbial growth was significantly affected by the whey protein amount as well as by the kind of prebiotic fiber...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28465256/a-combination-of-the-probiotic-and-prebiotic-product-can-prevent-the-germination-of-clostridium-difficile-spores-and-infection
#10
M Rätsep, S Kõljalg, E Sepp, I Smidt, K Truusalu, E Songisepp, J Stsepetova, P Naaber, R H Mikelsaar, M Mikelsaar
Clostridium difficile infection (CDI) is one of the most prevalent healthcare associated infections in hospitals and nursing homes. Different approaches are used for prevention of CDI. Absence of intestinal lactobacilli and bifidobacteria has been associated with C. difficile colonization in hospitalized patients. Our aim was to test a) the susceptibility of C. difficile strains of different origin and the intestinal probiotic Lactobacillus plantarum Inducia (DSM 21379) to various antimicrobial preparations incl...
April 29, 2017: Anaerobe
https://www.readbyqxmd.com/read/28463404/a-synbiotic-composed-of-lactobacillus-fermentum-cect5716-and-fos-prevents-the-development-of-fatty-acid-liver-and-glycemic-alterations-in-rats-fed-a-high-fructose-diet-associated-with-changes-in-the-microbiota
#11
Belén Rivero-Gutiérrez, Reyes Gámez-Belmonte, María Dolores Suárez, José Luis Lavín, Ana María Aransay, Mónica Olivares, Olga Martínez-Augustin, Fermín Sánchez de Medina, Antonio Zarzuelo
We investigated the effect of a high fructose diet (HFD) on Sprague Dawley rats and the impact of a synbiotic composed of Lactobacillus fermentum CECT5716 and fructooligosaccharides. Feeding the HFD for 5 weeks resulted in liver steatosis and insulin resistance but not obesity. These changes were associated with increased production of short-chain fatty acids and increased Bacteroidetes in feces, with an augmented Bacteroidetes/Firmicutes ratio, among other changes in the microbiota. In addition, barrier function was weakened, with increased LPS plasma levels...
May 2, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28431095/avi-lution%C3%A2-supplemented-at-1-0-or-2-0%C3%A2-g-kg-in-feed-improves-the-growth-performance-of-broiler-chickens-during-challenge-with-bacitracin-resistant-clostridium-perfringens
#12
L A Krueger, D A Spangler, D R Vandermyde, M D Sims, G A Ayangbile
Avi-Lution® is a defined, patented, synbiotic product containing Saccharomyces cerevisiae, Enterococcus faecium, and Bacillus spp. Broiler chickens (n = 1,250) were experimentally treated as uninoculated controls (uCon), inoculated controls (iCon) with Clostridium perfringens, or inoculated and treated with bacitracin methylene disalicylate (BMD) at 55 mg/kg as an infected/treated control or Avi-Lution® at 1.0 (AvL1) or 2.0 (AvL2) g/kg in feed for 42 d. Each treatment was applied to 10 replicate pens of 25 straight-run, newly hatched chicks...
April 18, 2017: Poultry Science
https://www.readbyqxmd.com/read/28390936/evidence-of-campylobacter-jejuni-reduction-in-broilers-with-early-synbiotic-administration
#13
Loredana Baffoni, Francesca Gaggìa, Giuliano Garofolo, Gabriella Di Serafino, Enrico Buglione, Elisabetta Di Giannatale, Diana Di Gioia
C. jejuni is considered a food safety concern to both public health authorities and consumers since it is the leading bacterial cause of food-borne gastroenteritis in humans. A high incidence of C. jejuni in broiler flocks is often correlated to pathogen recovery in retail poultry meat, which is the main source of human infection. In this work broiler chickens were fed with a synbiotic product mixed with conventional feed using two different administration strategies. The synbiotic was formulated with the microencapsulated probiotic Bifidobacterium longum PCB133 and a xylo-oligosaccharide (XOS)...
April 3, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28378421/fermented-cereal-beverages-from-probiotic-prebiotic-and-synbiotic-towards-nanoscience-designed-healthy-drinks
#14
REVIEW
Ivan Salmerón
The consumption of fermented food by human kind goes a long way back in history and there are as many types of fermented food as civilizations. Food science and technology has progressed from designing nutritional food towards food with health improvement characteristics such as functional foods. In this sense, the area of food with properties to improve gastrointestinal health like probiotics, prebiotics and synbiotics has been the most important segment within functional foods. Most of these products are dairy-based so the development of non-dairy gut improvement products has been of great interest for the food industry, resulting in the rise of cereal-based probiotic and synbiotic products...
April 4, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28363588/effects-of-synbiotics-on-immunity-and-disease-resistance-of-narrow-clawed-crayfish-astacus-leptodactylus-leptodactylus-eschscholtz-1823
#15
Omid Safari, Marina Paolucci, Hamidreza Ahmadnia Motlagh
The aim of this study was to evaluate the effects of prebiotics (mannanoligosaccharide and xylooligosaccharide), probiotics (Enterococcus faecalis and Pediococcus acidilactici) and synbiotics for 126 days on the immune responses, hemolymph indices, antioxidant enzymes, and biological responses after a 48-hour Aeromonas hydrophila exposure of sub-adult crayfish (11.45 ± 1.87 g). Most antibacterial activities were observed in the shell mucus of crayfish fed a diet containing xylooligosaccharide + E. faecalis and mannanoligosaccharide + Pediococcus acidilactici against Nocardia brasilience and Vibrio harveyi (p < 0...
May 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28356129/the-effects-of-probiotic-and-synbiotic-supplementation-on-metabolic-syndrome-indices-in-adults-at-risk-of-type-2-diabetes-study-protocol-for-a-randomized-controlled-trial
#16
Nazila Kassaian, Ashraf Aminorroaya, Awat Feizi, Parvaneh Jafari, Masoud Amini
BACKGROUND: The incidence of type 2 diabetes, cardiovascular diseases, and obesity has been rising dramatically; however, their pathogenesis is particularly intriguing. Recently, dysbiosis of the intestinal microbiota has emerged as a new candidate that may be linked to metabolic diseases. We hypothesize that selective modulation of the intestinal microbiota by probiotic or synbiotic supplementation may improve metabolic dysfunction and prevent diabetes in prediabetics. In this study, a synthesis and study of synbiotics will be carried out for the first time in Iran...
March 29, 2017: Trials
https://www.readbyqxmd.com/read/28350268/molecular-and-biopharmaceutical-investigation-of-alginate-inulin-synbiotic-coencapsulation-of-probiotic-to-target-the-colon
#17
Abdelbasset Atia, Ahmed I Gomma, Ismail Fliss, Eric Beyssac, Ghislain Garrait, Muriel Subirade
Colon targeting, as a site-specific delivery for oral formulation, remains a major challenge, especially for sensitive bioactive components such as therapeutic forms of phages, live attenuated virus and prebiotics-probiotics association. Synbiotics could be used to protect encapsulated probiotics during the gastrointestinal tract and control their release in the colon. To achieve these goals, effective prebiotics, such as inulin, could be combined with alginate - the most exploited polymer used for probiotic encapsulation - in the form of beads...
April 19, 2017: Journal of Microencapsulation
https://www.readbyqxmd.com/read/28345499/synbiotic-supplementation-in-lean-patients-with-non-alcoholic-fatty-liver-disease-a-pilot-randomised-double-blind-placebo-controlled-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
Fatemeh Mofidi, Hossein Poustchi, Zahra Yari, Babak Nourinayyer, Shahin Merat, Maryam Sharafkhah, Reza Malekzadeh, Azita Hekmatdoost
Although non-alcoholic fatty liver disease (NAFLD) is the leading aetiology of liver disorders in the world, there is no proven treatment for NAFLD patients with normal or low BMI. The aim of this study was to evaluate the efficacy of synbiotics supplementation in NAFLD patients with normal or low BMI. In this randomised, double-blind, placebo-controlled, clinical trial, fifty patients with NAFLD were assigned to take either a synbiotic supplement or a placebo capsule for 28 weeks. Both groups were advised to follow a healthy lifestyle...
March 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28336489/current-applications-selection-and-possible-mechanisms-of-actions-of-synbiotics-in-improving-the-growth-and-health-status-in-aquaculture-a-review
#19
REVIEW
Truong-Giang Huynh, Ya-Li Shiu, Thanh-Phuong Nguyen, Quoc-Phu Truong, Jiann-Chu Chen, Chun-Hung Liu
Synbiotics, a conjunction between prebiotics and probiotics, have been used in aquaculture for over 10 years. However, the mechanisms of how synbiotics work as growth and immunity promoters are far from being unraveled. Here, we show that a prebiotic as part of a synbiotic is hydrolyzed to mono- or disaccharides as the sole carbon source with diverse mechanisms, thereby increasing biomass and colonization that is established by specific crosstalk between probiotic bacteria and the surface of intestinal epithelial cells of the host...
May 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28314100/attenuated-mtor-signaling-and-enhanced-glucose-homeostasis-by-dietary-supplementation-with-lotus-seedpod-oligomeric-procyanidins-in-streptozotocin-stz-induced-diabetic-mice
#20
Xiaopeng Li, Yong Sui, Qian Wu, Bijun Xie, Zhida Sun
This study investigated the protective role of lotus seedpod oligomeric procyanidins (LSOPC) and synbiotics (Bifidobacterium Bb-12 and xylo-oligosaccharide) against high fat and streptozotocin (STZ)-induced diabetes. Administration of LSOPC or synbiotics had no effect on blood glucose in normal mice. Treatments with LSOPC for 12 weeks markedly reduced blood glucose, FFA, endotoxin, and GHbA1c and improved glucose homeostasis, lipid metabolism, and insulin levels. In addition, administration of LSOPC significantly reversed the increase of mTOR and p66(Shc) in liver, skeletal muscle, and white adipose tissue (WAT)...
May 8, 2017: Journal of Agricultural and Food Chemistry
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