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Synbiotics

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https://www.readbyqxmd.com/read/28644357/effect-of-synbiotic-on-the-gut-microbiota-of-cesarean-delivered-infants-a-randomized-double-blind-multicenter-study
#1
Mei Chin Chua, Kaouther Ben-Amor, Christophe Lay, Anne G E Neo, Wei Chin Chiang, Rajeshwar Rao, Charmaine Chew, Surasith Chaithongwongwatthana, Nipon Khemapech, Jan Knol, Voranush Chongsrisawat
We determined the effect of short-chain galacto-oligosaccharides (scGOS), long-chain fructo-oligosaccharides (lcFOS) and Bifidobacterium breve M-16V on the gut microbiota of cesarean-born infants. Infants were randomized to receive a standard formula (control), the same with scGOS/lcFOS and B. breve M-16V (synbiotic), or with scGOS/lcFOS (prebiotic) from birth until week 16, 30 subjects born vaginally were included as a reference group. Synbiotic supplementation resulted in a higher bifidobacteria proportion from day 3/5 (P < 0...
July 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28620481/tolerability-and-safety-of-the-intake-of-bovine-milk-oligosaccharides-extracted-from-cheese-whey-in-healthy-human-adults
#2
Jennifer T Smilowitz, Danielle G Lemay, Karen M Kalanetra, Elizabeth L Chin, Angela M Zivkovic, Melissa A Breck, J Bruce German, David A Mills, Carolyn Slupsky, Daniela Barile
Mechanistic research suggests a unique evolutionary relationship between complex milk oligosaccharides and cognate bifidobacteria enriched in breast-fed infants. Bovine milk oligosaccharides (BMO) were recently identified as structurally and functionally similar to human milk oligosaccharides. The present single-blind three-way crossover study is the first to determine the safety and tolerability of BMO consumption by healthy human participants (n 12) and its effects on faecal microbiota and microbial metabolism...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28608320/chronic-treatment-with-prebiotics-probiotics-and-synbiotics-attenuated-cardiac-dysfunction-by-improving-cardiac-mitochondrial-dysfunction-in-male-obese-insulin-resistant-rats
#3
Wannipa Tunapong, Nattayaporn Apaijai, Sakawdaurn Yasom, Pongpan Tanajak, Keerati Wanchai, Titikorn Chunchai, Sasiwan Kerdphoo, Sathima Eaimworawuthikul, Parameth Thiennimitr, Anchalee Pongchaidecha, Anusorn Lungkaphin, Wasana Pratchayasakul, Siriporn C Chattipakorn, Nipon Chattipakorn
PURPOSE: In metabolic syndrome, the composition of gut microbiota has been disrupted, and is associated with left ventricular (LV) dysfunction. Several types of prebiotics, probiotics, and synbiotics have been shown to exert cardioprotection by restoring gut microbiota from dysbiosis and reducing systemic inflammation. However, the effects of prebiotics such as xylooligosaccharides (XOS); probiotics such as Lactobacillus paracasei STII01 HP4, and synbiotics on metabolic and LV function in obese insulin-resistant rats have not been investigated...
June 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28594860/effect-of-probiotic-lactobacillus-on-lipid-profile-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#4
Yucheng Wu, Qingqing Zhang, Yin Ren, Zhongbao Ruan
OBJECTIVE: To assess the efficacy of probiotic Lactobacillus on serum lipids using a meta-analysis of randomized, controlled trials. METHODS: Fifteen studies containing 15 trials, with 976 subjects were included. The pooled WMD was calculated by random effects model. RESULTS: Probiotic Lactobacillus consumption significantly reduced TC by 0.26mmol/l (95% CI, -0.40 to -0.12) and LDL-C by 0.23mmol/l (95% CI, -0.36 to -0.10). Subgroup analysis of trials found significantly reduction of TC using L...
2017: PloS One
https://www.readbyqxmd.com/read/28591023/synbiotics-in-surgery-for-chronic-pancreatitis-a-hobson-s-choice
#5
Ashwin Rammohan, Jeswanth Sathyanesan, Ravichandran Palaniappan, Manoharan Govindan
No abstract text is available yet for this article.
July 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28591022/synbiotic-therapy-with-surgery-for-chronic-pancreatitis
#6
Ashwin Alwa, Abhishek Yadav, Hariharan Ramesh
No abstract text is available yet for this article.
July 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28588559/a-perspective-on-the-application-of-pro-synbiotics-in-clinical-practice
#7
Xiang-Dong Wu, Yu Chen, Wei Huang
No abstract text is available yet for this article.
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28583137/protective-effects-of-synbiotic-diets-of-bacillus-coagulans-lactobacillus-plantarum-and-inulin-against-acute-cadmium-toxicity-in-rats
#8
Dornoush Jafarpour, Seyed Shahram Shekarforoush, Hamid Reza Ghaisari, Saeed Nazifi, Javad Sajedianfard, Mohammad Hadi Eskandari
BACKGROUND: Cadmium is a heavy metal that causes oxidative stress and has toxic effects in humans. The aim of this study was to investigate the influence of two probiotics along with a prebiotic in preventing the toxic effects of cadmium in rats. METHODS: Twenty-four male Wistar rats were randomly divided into four groups namely control, cadmium only, cadmium along with Lactobacillus plantarum (1 × 109 CFU/day) and inulin (5% of feedstuff) and cadmium along with Bacillus coagulans (1 × 109 spore/day) and inulin (5% of feedstuff)...
June 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28556559/synbiotic-fermentation-for-the-co-production-of-lactic-and-lactobionic-acids-from-residual-dairy-whey
#9
Cristina García, Manuel Rendueles, Mario Díaz
Besides its properties as an antioxidant, stabilizer or acidifier, lactobionic acid has emerged as a potential prebiotic compound, raising the possibility of being included together with the probiotic microorganism Lactobacillus casei in novel functional fermented foods with synbiotic characteristics. Their manufacturing strategy could benefit from the recently implemented microbial synthesis of lactobionic acid by the strong producer Pseudomonas taetrolens, employing residual dairy whey as raw material. The phenomenon of amensalism established between Pseudomonas and Lactobacillus makes simultaneous fermentation unfeasible...
May 27, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28555037/evidence-of-the-anti-inflammatory-effects-of-probiotics-and-synbiotics-in-intestinal-chronic-diseases
#10
REVIEW
Julio Plaza-Díaz, Francisco Javier Ruiz-Ojeda, Laura Maria Vilchez-Padial, Angel Gil
Probiotics and synbiotics are used to treat chronic diseases, principally due to their role in immune system modulation and the anti-inflammatory response. The present study reviewed the effects of probiotics and synbiotics on intestinal chronic diseases in in vitro, animal, and human studies, particularly in randomized clinical trials. The selected probiotics exhibit in vitro anti-inflammatory properties. Probiotic strains and cell-free supernatants reduced the expression of pro-inflammatory cytokines via action that is principally mediated by toll-like receptors...
May 28, 2017: Nutrients
https://www.readbyqxmd.com/read/28552770/synbiotic-loaded-chitosan-ca-alginate-microparticles-reduces-inflammation-in-the-tnbs-model-of-rat-colitis
#11
Tanja Petreska Ivanovska, Kristina Mladenovska, Zoran Zhivikj, Maja Jurhar Pavlova, Ivica Gjurovski, Trpe Ristoski, Lidija Petrushevska-Tozi
New therapeutic strategies against inflammatory bowel disease (IBD) consider the usage of probiotics, prebiotics and synbiotics as beneficial for the intestinal microbial balance. Limitations of such an approach are addressed into difference in survival, persistence, colonization and variable effects among different probiotic strains, lack in understanding of probiotic mechanisms of action, as well the complex etiology of IBD. The anti-inflammatory activity of Lactobacillus casei 01 (L. casei 01) was assessed in trinitrobenzenesulphonic (TNBS) acid model of rat colitis when the probiotic was used alone and/or in combination with oligofructose-enriched inulin (Synergy 1), and as synbiotic (L...
May 25, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28533178/mucin-and-carbohydrate-stimulated-adhesion-and-subproteome-changes-of-the-probiotic-bacterium-lactobacillus-acidophilus-ncfm
#12
Hasan Ufuk Celebioglu, Sita Vaag Olesen, Kennie Prehn, Sampo J Lahtinen, Susanne Brix, Maher Abou Hachem, Birte Svensson
Adhesion to intestinal mucosa is a crucial property for probiotic bacteria. Adhesion is thought to increase host-bacterial interactions, thus potentially enabling health benefits to the host. Molecular events connected with adhesion and surface proteome changes were investigated for the probiotic Lactobacillus acidophilus NCFM cultured with established or emerging prebiotic carbohydrates as carbon source and in the presence of mucin, the glycoprotein of the epithelial mucus layer. Variation in adhesion to HT29-cells and mucin was associated with carbon source and mucin-induced subproteome abundancy differences...
May 19, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28504142/prebiotic-efficacy-and-mechanism-of-inulin-combined-with-inulin-degrading-lactobacillus-paracasei-i321-in-competition-with-salmonella
#13
Pochanart Kanjan, Tipparat Hongpattarakere
Inulin efficacy was proven for raising anti-Salmonella activity of the inulin-degrading Lactobacillus paracasei I321 (infant isolate) through the mechanisms of antibacterial secretion and competitive adhesion. Inulin significantly promoted competitive adhesion of L. paracasei I321 against many Gram-negative foodborne pathogenic bacteria. Salmonella Typhimurium SA2093 was completely suppressed under highly competitive niche of fecal microflora when inulin, L. paracasei I321, and their synbiotic combination were applied...
August 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28490394/synbiotic-supplementation-and-the-effects-on-clinical-and-metabolic-responses-in-patients-with-rheumatoid-arthritis-a-randomised-double-blind-placebo-controlled-trial
#14
Batol Zamani, Shima Farshbaf, Hamid R Golkar, Fereshteh Bahmani, Zatollah Asemi
Synbiotic intake may be associated with reduced inflammation in patients with rheumatoid arthritis (RA) due to optimised inflammatory markers, oxidative stress and insulin resistance. This research was conducted to assess the effects of synbiotic supplementation on the clinical and metabolic parameters of patients with RA. A total of fifty-four patients with RA were allocated into two groups to receive either a synbiotic capsule (n 27) or a placebo (n 27) for 8 weeks in this randomised, double-blind, placebo-controlled trial...
May 11, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28488210/food-additives-contaminants-and-other-minor-components-effects-on-human-gut-microbiota-a-review
#15
REVIEW
Paula Roca-Saavedra, Veronica Mendez-Vilabrille, Jose Manuel Miranda, Carolina Nebot, Alejandra Cardelle-Cobas, Carlos M Franco, Alberto Cepeda
Gut bacteria play an important role in several metabolic processes and human diseases, such as obesity and accompanying co-morbidities, such as fatty liver disease, insulin resistance/diabetes, and cardiovascular events. Among other factors, dietary patterns, probiotics, prebiotics, synbiotics, antibiotics, and non-dietary factors, such as stress, age, exercise, and climatic conditions, can dramatically impact the human gut microbiota equilibrium and diversity. However, the effect of minor food constituents, including food additives and trace contaminants, on human gut microbiota has received less attention...
May 9, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28485263/alternatives-to-antibiotics-for-maximizing-growth-performance-and-feed-efficiency-in-poultry-a-review
#16
U Gadde, W H Kim, S T Oh, Hyun S Lillehoj
With the increase in regulations regarding the use of antibiotic growth promoters and the rise in consumer demand for poultry products from 'Raised Without Antibiotics' or 'No Antibiotics Ever' flocks, the quest for alternative products or approaches has intensified in recent years. A great deal of research has focused on the development of antibiotic alternatives to maintain or improve poultry health and performance. This review describes the potential for the various alternatives available to increase animal productivity and help poultry perform to their genetic potential under existing commercial conditions...
May 9, 2017: Animal Health Research Reviews
https://www.readbyqxmd.com/read/28484432/rice-bran-and-probiotics-alter-the-porcine-large-intestine-and-serum-metabolomes-for-protection-against-human-rotavirus-diarrhea
#17
Nora Jean Nealon, Lijuan Yuan, Xingdong Yang, Elizabeth P Ryan
Human rotavirus (HRV) is a leading cause of severe childhood diarrhea, and there is limited vaccine efficacy in the developing world. Neonatal gnotobiotic pigs consuming a prophylactic synbiotic combination of probiotics and rice bran (Pro+RB) did not exhibit HRV diarrhea after challenge. Multiple immune, gut barrier protective, and anti-diarrheal mechanisms contributed to the prophylactic efficacy of Pro+RB when compared to probiotics (Pro) alone. In order to understand the molecular signature associated with diarrheal protection by Pro+RB, a global non-targeted metabolomics approach was applied to investigate the large intestinal contents and serum of neonatal gnotobiotic pigs...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28475793/effectiveness-of-probiotic-prebiotic-and-synbiotic-therapies-in-reducing-postoperative-complications-a-systematic-review-and-network-meta-analysis
#18
Nongyao Kasatpibal, JoAnne D Whitney, Surasak Saokaew, Kirati Kengkla, Margaret M Heitkemper, Anucha Apisarnthanarak
Background: Microbiome-directed therapies are increasingly used preoperatively and postoperatively to improve postoperative outcomes. Recently, the effectiveness of probiotics, prebiotics, and synbiotics in reducing postoperative complications (POCs) has been questioned. This systematic review aimed to examine and rank the effectiveness of these therapies on POCs in adult surgical patients. Methods: We searched for articles from PubMed, Embase, Cochrane, Web of Science, Scopus, and CINAHL plus...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28473897/determination-of-the-optimal-enrichment-artemia-franciscana-with-a-synbiotic-combination-of-probiotics-pediococcus-acidilactici-and-prebiotic-fructooligosaccharide
#19
(no author information available yet)
In this study the optimal amount of enriching Artemia franciscana with a synbiotic combination of Pediococcus acidilactici and fructooligosaccharide (FOS( was investigated. The experiment was conducted in a completely randomized design in ten treatments: multi-level probiotics P. acidilactici (1×10(9), 1×10(8) and 1× 10(7) CFU per L) and multi-level enriched prebiotic FOS (1, 2 and 5) g per L of solution and control. To evaluate the enrichment of adult artemia with each treatment, sampling was performed at 2, 4 and 6 hr after initiation of enrichment...
2017: Veterinary Research Forum
https://www.readbyqxmd.com/read/28471912/effect-of-synbiotic-on-the-gut-microbiota-of-caesarean-delivered-infants-a-randomized-double-blind-multicenter-study
#20
Mei Chien Chua, Kaouther Ben-Amor, Christophe Lay, Anne Goh Eng Neo, Wen Chin Chiang, Rajeshwar Rao, Charmaine Chew, Surasith Chaithongwongwatthana, Nipon Khemapech, Jan Knol, Voranush Chongsrisawat
We determined the effect of short-chain galacto-oligosaccharides (scGOS), long-chain fructo-oligosaccharides (lcFOS) and Bifidobacterium breve M-16 V on the gut microbiota of caesarean born infants. Infants were randomized to receive a standard formula (control), the same with scGOS/lcFOS and B. breve M-16 V (synbiotic), or with scGOS/lcFOS (prebiotic) from birth until week 16, 30 subjects born vaginally were included as a reference group. Synbiotic supplementation resulted in a higher bifidobacteria proportion from day 3/5 (p < 0...
May 3, 2017: Journal of Pediatric Gastroenterology and Nutrition
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