keyword
MENU ▼
Read by QxMD icon Read
search

Bile reflux

keyword
https://www.readbyqxmd.com/read/28214959/bile-reflux-scintigraphy-after-mini-gastric-bypass
#1
Tuure Saarinen, Jari Räsänen, Jarmo Salo, Antti Loimaala, Miia Pitkonen, Marja Leivonen, Anne Juuti
BACKGROUND: Significant weight-loss and diabetes remission have been reported after mini-gastric bypass (MGB). Concern has been raised regarding postoperative bile reflux (BR), but it has not been demonstrated in previous studies. We set out to find out if BR is evident in hepatobiliary scintigraphy after MGB. METHODS: Nine consecutive patients, seven with type 2 diabetes, underwent MGB (15 cm gastric tube, 250-275 cm biliary limb) at our institution with a 12-month follow-up, with none lost to follow-up...
February 18, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28205007/long-term-evaluation-of-biliary-reflux-after-experimental-one-anastomosis-gastric-bypass-in-rats
#2
Matthieu Bruzzi, Henri Duboc, Caroline Gronnier, Dominique Rainteau, Anne Couvelard, Maude Le Gall, André Bado, Jean-Marc Chevallier
BACKGROUND: Controversy remains regarding biliary reflux after one-anastomosis gastric bypass (OAGB). The aim of this "pilot" study was to analyze biliary reflux and its potential long-term consequences on esogastric mucosae in OAGB-operated rats. METHODS: Diet-induced obese rats were subjected to OAGB (n = 10) or sham (n = 4) surgery and followed up for 16 weeks. Evolution of weight and glucose tolerance was analyzed. Bile acid concentration measurement, histological and qRT-PCR analysis were performed in the esogastric segments...
February 15, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28189119/roux-en-y-duodenojejunostomy-for-surgical-management-of-isolated-duodenal-obstruction-due-to-chronic-pancreatitis
#3
Himanshu Sharma, Sanjay Marwah, Priyanka Singla, Amit Garg, Bittu Bhukkal
INTRODUCTION: Duodenal obstruction in case of chronic pancreatitis is a very rare occurrence and usually presents with gastric outlet obstruction. These cases sometimes require surgical intervention when conservative treatment fails. Gastrojejunostomy and vagotomy has conventionally been performed for management of these cases. PRESENTATION OF CASE: In this report, we present two cases of isolated duodenal obstruction due to chronic pancreatitis that were managed with Roux-en-Y duodenojejunostomy...
January 28, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28163716/billroth-ii-with-braun-enteroenterostomy-is-a-good-alternative-reconstruction-to-roux-en-y-gastrojejunostomy-in-laparoscopic-distal-gastrectomy
#4
Long-Hai Cui, Sang-Yong Son, Ho-Jung Shin, Cheulsu Byun, Hoon Hur, Sang-Uk Han, Yong Kwan Cho
Background. Although Billroth II (BII) reconstruction is simpler and faster than Billroth I or Roux-en-Y (RY) reconstruction in patients undergoing totally laparoscopic distal gastrectomy (TLDG), BII reconstruction is associated with several complications, including more severe bile reflux. BII Braun anastomosis may be a better alternative to RY reconstruction. Methods. This retrospective study included 56 consecutive patients who underwent TLDG for gastric cancer, followed by BII Braun or RY reconstruction, between January 2013 and December 2015...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28132059/does-braun-anastomosis-have-an-impact-on-the-incidence-of-delayed-gastric-emptying-and-the-extent-of-intragastric-bile-reflux-following-pancreatoduodenectomy-a-randomized-controlled-study
#5
Hironori Fujieda, Yukihiro Yokoyama, Akihiro Hirata, Hiroaki Usui, Yayoi Sakatoku, Masahide Fukaya, Masato Nagino
BACKGROUND/AIMS: This study investigated the impact of Braun anastomosis on the incidence of delayed gastric emptying (DGE) and on the intragastric bile reflux after pancreatoduodenectomy with Child reconstruction. METHODS: Sixty-eight patients who underwent subtotal stomach-preserving pancreatoduodenectomy were included. Patients were randomly assigned to a group with or without Braun anastomosis intraoperatively. Twenty-four-hour intragastric bilirubin monitoring was performed to investigate the extent of intragastric bile reflux after surgery...
January 28, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28109253/quality-of-life-and-impact-of-bile-reflux-after-retro-colic-retro-gastric-gastrojejunostomy-in-whipple-surgery
#6
Rohan Chaminda Siriwardana, Rajapaksha Walimuni Mudiyanselage Anuradha Lokubandara, Shivanthi Janaki De Silva Hewavisenthi, Saumya Kumuduni Liyanage, Dona Subani Priyangika Jayatunge, Chandika Anuradha Habarakada Liyanage
BACKGROUND: Delayed gastric emptying and bile reflux are common concerns in long-term survivors after Whipple surgery. The study was designed to assess modified retro colic retro gastric gastrojejunostomy in reducing macro and microscopic bile reflux and impact on dyspepsia related quality of life in long-term survivors. METHODS: Out of 43 patients operated, 23 long-term survivors were included. All underwent gastroscopy and bile reflux was grouped as normal, yellowish bile lakes and presence of greenish bile lakes...
January 21, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28100991/sphincter-of-oddi-dysfunction-a-perplexing-presentation
#7
Sana Ahmad Din, Iman Naimi, Mirza Beg
Sphincter of Oddi dysfunction is caused by stenosis or dyskinesia of the sphincter of Oddi, leading to blockage of bile drainage from the common bile duct. We present the case of a 16-year-old female with chronic abdominal pain who underwent laparoscopic cholecystectomy for cholelithiasis but continued to experience abdominal pain, nausea, and vomiting along with persistently elevated ALT and AST levels. Postoperative abdominal ultrasound was nondiagnostic. Esophagogastroduodenoscopy showed mild reflux esophagitis and mild chronic Helicobacter pylori-negative gastritis...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28078458/superiority-of-laparoscopic-proximal-gastrectomy-with-hand-sewn-esophagogastrostomy-over-total-gastrectomy-in-improving-postoperative-body-weight-loss-and-quality-of-life
#8
Tatsuto Nishigori, Hiroshi Okabe, Shigeru Tsunoda, Hisashi Shinohara, Kazutaka Obama, Hisahiro Hosogi, Shigeo Hisamori, Kikuko Miyazaki, Takeo Nakayama, Yoshiharu Sakai
BACKGROUND: Proximal gastrectomy is not widely performed because the procedure is complicated, particularly under laparoscopy. We developed a simple laparoscopic technique of hand-sewn esophagogastrostomy with an anti-reflux mechanism. This study aimed to evaluate and compare the postoperative body weight loss (BWL) and quality of life (QOL) following laparoscopic proximal gastrectomy (LPG) and laparoscopic total gastrectomy (LTG) in patients with upper gastric cancer. METHODS: We retrospectively analyzed patients with stage I upper gastric cancer undergoing LPG or LTG at Kyoto University Hospital between March 2006 and June 2014...
January 11, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28062891/surgical-techniques-for-esophageal-replacement-in-children
#9
REVIEW
Shilpa Sharma, Devendra K Gupta
PURPOSE: Surgical techniques for esophageal replacement (ER) in children include colon interposition, gastric tube, gastric transposition, and jejunal interposition. This review evaluates the merits and demerits of each. METHOD: Surgical techniques, complications, and outcome of ER are reviewed over last seven decades. RESULTS: Colon interposition is the time-tested procedure with minimal and less serious complications. Long-term complications include reflux, halitosis, colonic segment dilatation, and anastomotic stricture, sometimes requiring surgical interventions especially for dilatation and reflux...
January 6, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28036160/bile-acids-a-potential-role-in-the-pathogenesis-of-pharyngeal-malignancy
#10
Z Shellman, A Aldhahrani, B Verdon, M Mather, V Paleri, J Wilson, J Pearson, C Ward, J Powell
OBJECTIVE: Gastro-oesophageal reflux disease is thought to be a risk factor for head and neck malignancies. Bile acids are one of the principle components of gastric refluxate and have previously been implicated in the development of oesophageal and bowel malignancies. There is clear evidence that bile acids reflux into the laryngopharynx. Despite this, the carcinogenic properties of bile acids in this area are yet to be fully identified. We therefore investigated the potential role of bile acids in pharyngeal malignancy, through the highly conserved process of epithelial-mesenchymal transition (EMT)...
December 30, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28002646/elevated-bile-amylase-level-without-pancreaticobiliary-maljunction-is-a-risk-factor-for-gallbladder-carcinoma
#11
Takaaki Fujimoto, Takao Ohtsuka, Yohei Nakashima, Yoshitaka Gotoh, Kenjiro Date, Yasuhisa Mori, Yoshihiko Sadakari, Shunichi Takahata, Yoshinao Oda, Masafumi Nakamura
BACKGROUND: Elevated bile amylase level in patients with pancreaticobiliary maljunction (PBM) or high confluence of pancreaticobiliary ducts (HCPBD) is well known as a risk factor for gallbladder carcinoma (GBC) development. However, the effects of occult pancreaticobiliary reflux (OPR), a condition characterized by high bile amylase level in the presence of an anatomically normal pancreaticobiliary junction, on GBC development remain unclear. The aim of this study was to assess the relationship between OPR and GBC...
February 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/27993699/gastroesophageal-mucosal-injury-after-cholecystectomy-an-indication-for-surveillance
#12
Syeda Nadia Shah Gilani, Gary Alan Bass, Natallia Kharytaniuk, Michelle R Downes, Emer Frances Caffrey, Iqbal Tobbia, Thomas Noel Walsh
BACKGROUND: Cholecystectomy alters bile release dynamics from pulsatile meal-stimulated to continuous, and results in retrograde duodeno-gastric bile reflux(DGR). Bile is implicated in mucosal injury following gastric surgery, but whether cholecystectomy causes esophago-gastric mucosal inflammation, thus increasing the risk of metaplasia, is unclear. STUDY DESIGN: This study examined whether cholecystectomy-induced DGR promotes chronic inflammatory mucosal changes of the stomach and/or at the esophago-gastric junction(EGJ)...
December 16, 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27986575/conversion-of-one-anastomosis-gastric-bypass-mini-gastric-bypass-to-roux-en-y-gastric-bypass-for-bile-reflux-gastritis-after-failed-braun-jejunojejunostomy
#13
Abdelrahman Nimeri, Talat Al Shaban, Ahmed Maasher
No abstract text is available yet for this article.
October 31, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27986173/liver-function-assessment-by-magnetic-resonance-imaging
#14
Emre Ünal, Deniz Akata, Musturay Karcaaltincaba
Liver function assessment by hepatocyte-specific contrast-enhanced magnetic resonance imaging is becoming a new biomarker. Liver function can be assessed by T1 mapping (reduction rate) and signal intensity measurement (relative enhancement ratio) before and after GD-EOB-DTPA (gadoxetic acid) administration, as alternative to Tc-99m galactosyl serum albumin scintigraphy, 99m Tc-labeled mebrofenin scintigraphy, and indocyanine green clearance test. Magnetic resonance imaging assessment of liver function can enable diagnosis of cirrhosis, nonalcoholic fatty liver disease associated fibrosis and steatohepatitis, primary sclerosing cholangitis, toxic hepatitis, and chemotherapy and radiotherapy-related changes, which may be only visible on hepatobiliary phase images...
December 2016: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/27973541/the-in-vitro-effect-of-acidic-pepsin-on-nuclear-factor-kappab-activation-and-its-related-oncogenic-effect-on-normal-human-hypopharyngeal-cells
#15
Clarence T Sasaki, Julia Toman, Dimitra Vageli
BACKGROUND: Extra-esophageal carcinogenesis has been widely discussed in relation to the chronic effects of laryngopharyngeal reflux and most prominently with pepsin historically central to this discussion. With refluxate known to include gastric (pepsin) and duodenal (bile) fluids, we recently demonstrated the mechanistic role of NF-κB in mediating the preneoplastic effects of acidic-bile. However, the role of pepsin in promoting hypopharyngeal premalignant events remains historically unclear...
2016: PloS One
https://www.readbyqxmd.com/read/27909875/one-anastomosis-gastric-bypass-why-biliary-reflux-remains-controversial
#16
Matthieu Bruzzi, Jean-Marc Chevallier, Sébastien Czernichow
One-anastomosis gastric bypass is an alternative to the "gold-standard" Roux-en-Y gastric bypass. This technique appears to be safe and efficient, but controversy remains regarding the long-term theoretical risk of subsequent biliary reflux and its possible complications, such as cancer. The aim of the present narrative review was to summarize some of the current thoughts on biliary reflux. Research has established that exposure to chronic bile reflux in humans and rats (outside the "bariatric surgery" box) induce esophageal intestinal metaplasia and esophageal adenocarcinoma...
February 2017: Obesity Surgery
https://www.readbyqxmd.com/read/27889422/symptomatic-pancreatic-duct-stones-in-the-disconnected-bile-duct-a-case-series
#17
Alexander R Ende, Shayan Irani, Richard A Kozarek
BACKGROUND: Pancreaticobiliary maljunction (PBM) refers to the union of the pancreatic and biliary ducts outside of the duodenal wall. Patients are at increased risk of bile duct and gallbladder cancer, likely secondary to pancreatic juice refluxing into the biliary tree, and it is recommended that they undergo biliary diversion. METHODS: This is a case series of all patients in our institution with PBM and bilioenteric anastomosis who presented with symptomatic pancreatic duct stones in a disconnected bile duct...
November 14, 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/27888615/unconjugated-secondary-bile-acids-activate-the-unfolded-protein-response-and-induce-golgi-fragmentation-via-a-src-kinase-dependant-mechanism
#18
Ruchika Sharma, Francis Quilty, John F Gilmer, Aideen Long, Anne-Marie Byrne
Bile acids are components of gastro-duodenal refluxate and regarded as causative agents in oesophageal disease but the precise mechanisms are unknown. Here we demonstrate that a specific subset of physiological bile acids affect the protein secretory pathway by inducing ER stress, activating the Unfolded Protein Response (UPR) and causing disassembly of the Golgi apparatus in oesophageal cells. Deoxycholic acid (DCA), Chemodeoxycholic acid (CDCA) and Lithocholic acid (LCA) activated the PERK arm of the UPR, via phosphorylation of eIF2α and up-regulation of ATF3, CHOP and BiP/GRP78...
January 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/27873093/fatty-acids-in-a-high-fat-diet-potentially-induce-gastric-parietal-cell-damage-and-metaplasia-in-mice
#19
Yuki Hirata, Takuhito Sezaki, Miwa Tamura-Nakano, Chinatsu Oyama, Teruki Hagiwara, Takamasa Ishikawa, Shinji Fukuda, Kazuhiko Yamada, Kazuhide Higuchi, Taeko Dohi, Yuki I Kawamura
BACKGROUND: Obesity is associated with risk of adenocarcinoma in the proximal stomach. We aimed to identify the links between dietary fat and gastric premalignant lesions. METHODS: C57BL/6 mice were fed high fat diet (HFD), and gastric mucosa was histologically analysed. Morphological changes were also analysed using an electron microscope. Transcriptome analysis of purified parietal cells was performed, and non-parietal gastric corpus epithelial cells were subjected to single-cell gene-expression profiling...
November 21, 2016: Journal of Gastroenterology
https://www.readbyqxmd.com/read/27832356/risk-factors-for-intestinal-metaplasia-in-a-southeastern-chinese-population-an-analysis-of-28-745-cases
#20
Jian-Xia Jiang, Qing Liu, Bing Zhao, Hai-Han Zhang, Huai-Ming Sang, Soyfoo-Muhammad Djaleel, Guo-Xin Zhang, Shun-Fu Xu
PURPOSE: To identify risk factors for intestinal metaplasia in a southeastern Chinese population. METHODS: Subjects who underwent upper GI endoscopy and endoscopic biopsy in the First Affiliated Hospital of Nanjing Medical University from 2008 to 2013 were included into this study. Various demographic, geographic, clinical and pathological data were analyzed separately to identify risk factors for intestinal metaplasia. RESULTS: The incidence of intestinal metaplasia differed significantly in 17 municipal areas ranging from 16...
March 2017: Journal of Cancer Research and Clinical Oncology
keyword
keyword
9157
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"