keyword
MENU ▼
Read by QxMD icon Read
search

Bile reflux

keyword
https://www.readbyqxmd.com/read/29649994/bile-acids-at-neutral-and-acidic-ph-induce-apoptosis-and-gene-cleavages-in-nasopharyngeal-epithelial-cells-implications-in-chromosome-rearrangement
#1
Sang-Nee Tan, Sai-Peng Sim
BACKGROUND: Chronic rhinosinusitis (CRS) increases the risk of developing nasopharyngeal carcinoma (NPC) while nasopharyngeal reflux is known to be one of the major aetiological factors of CRS. Bile acid (BA), the component of gastric duodenal contents, has been recognised as a carcinogen. BA-induced apoptosis was suggested to be involved in human malignancies. Cells have the potential and tendency to survive apoptosis. However, cells that evade apoptosis upon erroneous DNA repair may carry chromosome rearrangements...
April 12, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29606884/proton-pump-inhibitor-refractory-gastroesophageal-reflux-disease-challenges-and-solutions
#2
REVIEW
Joseph Mermelstein, Alanna Chait Mermelstein, Maxwell M Chait
A significant percentage of patients with gastroesophageal reflux disease (GERD) will not respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are numerous and diverse, and include adherence, persistent acid, functional disorders, nonacid reflux, and PPI bioavailability. The evaluation should start with a symptom assessment and may progress to imaging, endoscopy, and monitoring of esophageal pH, impedance, and bilirubin. There are a variety of pharmacologic and procedural interventions that should be selected based on the underlying mechanism of PPI failure...
2018: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/29576309/preventive-effect-of-oral-hangeshashinto-tj-14-on-the-development-of-reflux-induced-esophageal-cancer
#3
Tomoharu Miyashita, Toru Kono, Daisuke Matsui, Yuki Yamazaki, Daichi Sadatomi, Naoki Fujitsuka, Shinichi Nakanuma, Koichi Okamoto, Isamu Makino, Jun Kinoshita, Keishi Nakamura, Katsunobu Oyama, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, Kenichi Mukaisho, John W Harmon, Tetsuo Ohta
BACKGROUND: Prostaglandin E2 is one of the potential products that promotes development of tumors and also is a strong inducer of M2 phenotype macrophages, which contribute to tumor development in the immunosuppressed microenvironment. Hangeshashinto (TJ-14), a Japanese traditional medicine (Kampo medicine), has been reported to be effective in preventing chemotherapy-induced oral mucositis through the reduction of prostaglandin E2. We previously developed a surgical rat reflux model of esophageal cancer and used this well-established animal model to investigate the action of TJ-14 in preventing esophageal cancer...
March 22, 2018: Surgery
https://www.readbyqxmd.com/read/29530597/the-incidence-of-complications-associated-with-loop-duodeno-ileostomy-after-single-anastomosis-duodenal-switch-procedures-among-1328-patients-a-multicenter-experience
#4
Amit Surve, Daniel Cottam, Andres Sanchez-Pernaute, Antonio Torres, Joshua Roller, Yong Kwon, Joshua Mourot, Bleu Schniederjan, Bo Neichoy, Paul Enochs, Michael Tyner, Jon Bruce, Scott Bovard, Mitchell Roslin, Muhammad Jawad, Andre Teixeira, Myur Srikanth, Jason Free, Hinali Zaveri, David Pilati, Jamie Bull, LeGrand Belnap, Christina Richards, Walter Medlin, Rena Moon, Austin Cottam, Sarah Sabrudin, Samuel Cottam, Aneesh Dhorepatil
BACKGROUND: The single-anastomosis duodenal switch procedure is a type of duodenal switch that involves a loop anastomosis rather than traditional Roux-en-Y reconstruction. To date, there have been no multicenter studies looking at the complications associated with post-pyloric loop reconstruction. OBJECTIVES: The aim of the study was to report the incidence of complications associated with loop duodeno-ileostomy (DI) following single-anastomosis duodenal switch (SADS) procedures...
February 2, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29529473/in-vivo-short-term-topical-application-of-bay-11-7082-prevents-the-acidic-bile-induced-mrna-and-mirna-oncogenic-phenotypes-in-exposed-murine-hypopharyngeal-mucosa
#5
Clarence T Sasaki, Sotirios G Doukas, Dimitra P Vageli
PURPOSE: Bile-containing gastroesophageal reflux may promote cancer at extraesophageal sites. Acidic bile can accelerate NF-κB activation and molecular events, linked to premalignant changes in murine hypopharyngeal mucosa (HM). We hypothesize that short-term in vivo topical application of NF-κB inhibitor BAY 11-7082 can prevent acidic bile-induced early preneoplastic molecular events, suggesting its potential role in disease prevention. EXPERIMENTAL DESIGN: We topically exposed HM (C57Bl/6j wild-type) to a mixture of bile acids at pH 3...
March 9, 2018: Neoplasia: An International Journal for Oncology Research
https://www.readbyqxmd.com/read/29511408/worsening-of-acute-cholangitis-caused-by-a-bile-duct-stone-after-hospitalization-a-case-series
#6
Tetsuro Akashi, Yuichi Tachibana, Susumu Matsuo, Junya Gibo
Acute cholangitis is a fatal condition if inadequately treated. It is possible to underestimate the severity of the condition because bacterial cultures are not immediately available. We evaluated the clinical features of patients with cholangitis due to bile duct stones who were diagnosed with severe bacteremia at the time of hospitalization, but not at the time of the initial visit. We conducted a retrospective analysis of cases of endoscopic retrograde cholangiopancreatography performed between January 2007 and October 2011 in patients with bile duct stones complicated by cholangitis...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29509543/management-of-pylorus-during-esophagectomy-to-drain-or-not-to-drain
#7
Stylianos Kykalos, Evangelia Ntikoudi
Dear Editor, delayed gastric emptying due to bilateral vagotomy after esophagectomy, has been associated with increased aspiration rates, prolonged hospital stay and impaired quality of life. A pyloric drainage procedure in an effort to reduce its incidence, most commonly a pyloroplasty, represented for years a standard part of distal esophagectomy. This trend has been reevaluated nowadays and the question that still remains open is whether we should further keep on draining pylorus during esophagectomy or not...
January 2018: Chirurgia
https://www.readbyqxmd.com/read/29505908/new-causes-for-the-old-problem-of-bile-reflux-gastritis
#8
Marshall E McCabe, Christen K Dilly
No abstract text is available yet for this article.
March 2, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29479444/comparative-analysis-of-different-hepatico-jejunostomy-techniques-for-treating-adult-type-i-choledochal-cyst
#9
Wenjie Ma, Yongqiong Tan, Anuj Shrestha, Fuyu Li, Rongxing Zhou, Junke Wang, Haijie Hu, Qin Yang
Objective: To compare Roux-en-Y hepatico-jejunostomy with complete resection of the cyst or incomplete resection with 1-cm remnant proximal cyst wall in treating adult type I choledochal cyst (CC). Methods: The medical records of 267 adult patients with type I CC from January 1998 to December 2015 were reviewed retrospectively. Among them, 171 underwent Roux-en-Y hepatico-jejunostomy with complete resection (PBD 0-cm group) and 96 underwent Roux-en-Y hepatico-jejunostomy with 1-cm proximal cyst wall left (PBD 1-cm group)...
February 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/29464041/inhibition-of-nf-%C3%AE%C2%BA-b-prevents-the-acidic-bile-induced-oncogenic-mrna-phenotype-in-human-hypopharyngeal-cells
#10
Dimitra P Vageli, Sotirios G Doukas, Clarence T Sasaki
Bile-containing gastro-duodenal reflux has been clinically considered an independent risk factor in hypopharyngeal carcinogenesis. We recently showed that the chronic effect of acidic bile, at pH 4.0, selectively induces NF- κ B activation and accelerates the transcriptional levels of genes, linked to head and neck cancer, in normal hypopharyngeal epithelial cells. Here, we hypothesize that NF- κ B inhibition is capable of preventing the acidic bile-induced and cancer-related mRNA phenotype, in treated normal human hypopharyngeal cells...
January 19, 2018: Oncotarget
https://www.readbyqxmd.com/read/29456774/gastric-aspiration-and-its-role-in-airway-inflammation
#11
REVIEW
E B Hunt, A Sullivan, J Galvin, J MacSharry, D M Murphy
Gastro-Oesophageal Reflux (GOR) has been associated with chronic airway diseases while the passage of foreign matter into airways and lungs through aspiration has the potential to initiate a wide spectrum of pulmonary disorders. The clinical syndrome resulting from such aspiration will depend both on the quantity and nature of the aspirate as well as the individual host response. Aspiration of gastric fluids may cause damage to airway epithelium, not only because acidity is toxic to bronchial epithelial cells but also due to the effect of digestive enzymes such as pepsin and bile salts...
2018: Open Respiratory Medicine Journal
https://www.readbyqxmd.com/read/29435660/indications-for-total-esophagogastric-dissociation-in-children-with-gastroesophageal-reflux-disease
#12
REVIEW
Yujiro Tanaka, Takahisa Tainaka, Hiroo Uchida
Total esophagogastric dissociation (TED) is used to treat gastroesophageal reflux (GER) after failed fundoplication in neurologically impaired patients. It is now performed for some otherwise healthy patients with severe GER. In this procedure, the gastrointestinal tract is reconstructed in a non-physiological way with a Roux-en-Y esophagojejunal anastomosis and jejuno-jejunostomy. Although TED eliminates almost all GER, some patients experience late complications. In this review, we investigated the long-term outcomes after TED to determine the best indications...
February 12, 2018: Surgery Today
https://www.readbyqxmd.com/read/29399801/the-potential-role-of-bile-acids-in-acquired-laryngotracheal-stenosis
#13
Adil Aldhahrani, Jason Powell, Shameem Ladak, Mahmoud Ali, Simi Ali, Bernard Verdon, Jeffrey Pearson, Chris Ward
OBJECTIVE: Gastroesophageal reflux is thought to be a risk factor for laryngotracheal stenosis. Bile acids are a component of gastric refluxate and have previously been implicated in the development of fibrosis in other airway subsites. There is clear evidence that bile acids reflux into the upper airway. We therefore investigated the potential role of bile acids in the pathophysiology of laryngotracheal fibrosis and stenosis, specifically investigating the highly conserved process of epithelial-mesenchymal transition (EMT)...
February 5, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29390281/comparison-of-safety-and-effectiveness-between-laparoscopic-mini-gastric-bypass-and-laparoscopic-sleeve-gastrectomy-a-meta-analysis-and-systematic-review
#14
REVIEW
Fu-Gang Wang, Zhao-Peng Yu, Wen-Mao Yan, Ming Yan, Mao-Min Song
BACKGROUND: The laparoscopic mini-gastric bypass is a newly emerged surgical procedure in recent years. Owe to safe and simple process and effective outcomes, laparoscopic mini-gastric bypass has quickly become one of the most popular procedures in some countries. The safety and effectiveness of laparoscopic mini-gastric bypass versus laparoscopic sleeve gastrectomy remain unclear. METHODS: A systematic literature search was performed in PubMed, Embase, Cochrane library from inception to May 20, 2017...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29341148/outcomes-after-prophylactic-gastrectomy-for-hereditary-diffuse-gastric-cancer
#15
R T van der Kaaij, J P van Kessel, J M van Dieren, P Snaebjornsson, O Balagué, F van Coevorden, L E van der Kolk, K Sikorska, A Cats, J W van Sandick
BACKGROUND: Patients with hereditary diffuse gastric cancer and a CDH1 mutation have a 60-80 per cent lifetime risk of developing diffuse gastric cancer. Total prophylactic gastrectomy eliminates this risk, but is associated with considerable morbidity. The effectiveness (removal of all gastric mucosa) and outcomes of this procedure were evaluated retrospectively. METHODS: All consecutive individuals undergoing a prophylactic gastrectomy for a CDH1 mutation or gastric signet ring cell foci at the authors' institute between 2005 and 2017 were included...
January 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29340827/single-incision-laparoscopic-hepaticojejunostomy-for-children-with-perforated-choledochal-cysts
#16
Mei Diao, Long Li, Wei Cheng
BACKGROUND: Conventionally, perforated choledochal cyst (CDC) is a contraindication of laparoscopic treatment. The current study is to evaluate efficacy of single-incision laparoscopic hepaticojejunostomy (SILH) in children with perforated CDCs. METHODS: One hundred and thirty-three children with perforated CDCs who underwent SILHs in our hospital between August 2011 and August 2017 were reviewed. RESULTS: Fifteen (11.3%) patients were converted to open procedures due to severe adhesions and oozing...
January 16, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29340552/single-anastomosis-gastric-bypass-one-anastomosis-gastric-bypass-or-mini-gastric-bypass-the-experience-with-billroth-ii-must-be-considered-and-is-a-challenge-for-the-next-years
#17
Italo Braghetto, Attila Csendes
INTRODUCTION: Single anastomosis gastric bypass (one anastomosis gastric bypass or mini-gastric bypass) has been presented as an option of surgical treatment for obese patients in order to reduce operation time and avoiding eventual postoperative complications after Roux-en-Y gastric bypass.The main late complication could be related to bile reflux. AIM: To report the experiences published after Billroth II anastomosis and its adverse effects regarding symptoms and damage on the gastric and esophageal mucosa ...
October 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/29313514/upper-gastrointestinal-tract-endoscopic-lesions-in-a-rural-african-hospitalo-252-endoscopies-at-the-kara-university-hospital-togo
#18
O Bouglouga, A Bagny, L M Lawson-Ananissoh, K Amanga, R El-Hadj Yakoubou, L Kaaga, M Djibril, D Redah
To analyze the indications for upper gastrointestinal endoscopy (UGIE) and determine the frequency of the pathological findings observed in rural areas of Africa. This retrospective study includes 9 series of 5-day visits to perform these examinations. Patients were informed of the presence of the endoscopy team by a bulletin on a rural radio station and by general practitioners at the Kara University Hospital. Patients were recruited from the hospital clinics and from the general population of the Kara region...
November 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29249586/medium-to-long-term-outcomes-of-bariatric-surgery-in-older-adults-with-super-obesity
#19
Aly Elbahrawy, Alexandre Bougie, Sarah-Eve Loiselle, Sebastian Demyttenaere, Olivier Court, Amin Andalib
BACKGROUND: Indications and outcomes of bariatric surgery in older adults suffering from morbid obesity remain controversial. We aimed to evaluate safety and medium to long-term outcomes of bariatric procedures in this patient population. SETTING: University Hospital, Canada. METHODS: This is a single-center retrospective study of a prospectively collected database. We included patients aged ≥60 years who underwent sleeve gastrectomy, Roux-en-Y gastric bypass, or biliopancreatic diversion with duodenal switch between January 2006 and December 2014 and had at least 2 years of follow-up...
April 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29241102/utility-of-hepatobiliary-scintigraphy-for-recurrent-reflux-cholangitis-following-choledochojejunostomy-a-case-report
#20
Masateru Yamamoto, Hiroyuki Tahara, Michinori Hamaoka, Seiichi Shimizu, Shintaro Kuroda, Masahiro Ohira, Kentaro Ide, Tsuyoshi Kobayashi, Hideki Ohdan
INTRODUCTION: Reflux cholangitis is a frequent complication of Roux-en-Y choledochojejunostomy. PRESENTATION OF CASE: A 68-year-old male underwent left lobectomy of the liver, bile duct resection and choledochojejunostomy for intrahepatic cholangiocarcinoma located in Segment 2 of the liver, 40mm in diameter with a lymph node metastasis 5 years ago. He had frequent recurrences of postoperative reflux cholangitis and hepatic abscesses and was treated with antibiotics each time...
2018: International Journal of Surgery Case Reports
keyword
keyword
9157
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"