Camilla Panduro Nielsen, Ebbe Laugaard Lorenzen, Kenneth Jensen, Nis Sarup, Carsten Brink, Bob Smulders, Anne Ivalu Sander Holm, Eva Samsøe, Martin Skovmos Nielsen, Patrik Sibolt, Peter Sandegaard Skyt, Ulrik Vindelev Elstrøm, Jørgen Johansen, Ruta Zukauskaite, Jesper Grau Eriksen, Mohammad Farhadi, Maria Andersen, Christian Maare, Jens Overgaard, Cai Grau, Jeppe Friborg, Christian Rønn Hansen
BACKGROUND: In the Danish Head and Neck Cancer Group (DAHANCA) 35 trial, patients are selected for proton treatment based on simulated reductions of Normal Tissue Complication Probability (NTCP) for proton compared to photon treatment at the referring departments. After inclusion in the trial, immobilization, scanning, contouring and planning are repeated at the national proton centre. The new contours could result in reduced expected NTCP gain of the proton plan, resulting in a loss of validity in the selection process...
September 13, 2023: Acta Oncologica