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https://www.readbyqxmd.com/read/29028066/complex-molecular-surfaces-and-interfaces-concluding-remarks
#1
David B Amabilino, Steven L Tait
This paper is derived from our concluding remarks presentation and the ensuing conversations at the Faraday Discussions meeting on Complex Molecular Surfaces and Interfaces, Sheffield, UK, 24th-26th July 2017. This meeting was comprised of sessions on understanding the interaction of molecules with surfaces and their subsequent organisation, reactivity or properties from both experimental and theoretical perspectives. This paper attempts to put these presentations in the wider context and focuses on topics that were debated during the meeting and where we feel that opportunities lie for the future development of this interdisciplinary research area...
October 13, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/29027903/functional-dichotomy-in-spinal-vs-prefrontal-projecting-locus-coeruleus-modules-splits-descending-noradrenergic-analgesia-from-ascending-aversion-and-anxiety-in-rats
#2
Stefan Hirschberg, Yong Li, Andrew Randall, Eric J Kremer, Anthony E Pickering
The locus coeruleus (LC) projects throughout the brain and spinal cord and is the major source of central noradrenaline. It remains unclear whether the LC acts functionally as a single global effector or as discrete modules. Specifically, while spinal-projections from LC neurons can exert analgesic actions, it is not known whether they can act independently of ascending LC projections. Using viral vectors taken up at axon terminals, we expressed chemogenetic actuators selectively in LC neurons with spinal (LC:(SC)) or prefrontal cortex (LC:(PFC)) projections...
October 13, 2017: ELife
https://www.readbyqxmd.com/read/29027513/-sharing-patient-information-with-neighbourhood-social-support-teams-a-legal-perspective
#3
V E T Dörenberg
The beginning of 2015 saw the transition of responsibility for social care, youth care and participation of vulnerable groups in the Netherlands from the government to local authorities. A large majority of municipalities chose to work with neighbourhood social support teams. Their main purpose is to offer integrated care to citizens. Integrated care requires information-sharing between organisations and (healthcare) professionals. Are medical practitioners authorized to share patient information with neighbourhood social support teams? Legal analysis shows that a medical practitioner may play one of the following three roles when sharing information with such teams: the role of referrer, the role of expert or the role of informant...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29027257/review-article-consensus-statements-on-therapeutic-drug-monitoring-of-anti-tumour-necrosis-factor-therapy-in-inflammatory-bowel-diseases
#4
REVIEW
N Mitrev, N Vande Casteele, C H Seow, J M Andrews, S J Connor, G T Moore, M Barclay, J Begun, R Bryant, W Chan, C Corte, S Ghaly, D A Lemberg, V Kariyawasam, P Lewindon, J Martin, R Mountifield, G Radford-Smith, P Slobodian, M Sparrow, C Toong, D van Langenberg, M G Ward, R W Leong
BACKGROUND: Therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD) patients receiving anti-tumour necrosis factor (TNF) agents can help optimise outcomes. Consensus statements based on current evidence will help the development of treatment guidelines. AIM: To develop evidence-based consensus statements for TDM-guided anti-TNF therapy in IBD. METHODS: A committee of 25 Australian and international experts was assembled. The initial draft statements were produced following a systematic literature search...
October 13, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29026189/sustainability-and-transformation-partnerships-what-are-they-and-how-do-they-affect-dentistry
#5
J Lewney
Sustainability and Transformation Partnerships or 'STPs' have been formed from NHS and social care providers, commissioners, and local councils in 44 areas covering the whole of England to improve the care they provide. Proposals, known as 'Sustainability and Transformation Plans' have been developed that address the needs of the whole population of each area, rather than the needs of each individual organisation. STPs are fundamental to how care will be delivered and commissioned in the future and have recently been portrayed in the media as the vehicle for cuts to NHS services...
October 27, 2017: British Dental Journal
https://www.readbyqxmd.com/read/29025847/exploring-the-role-of-the-nurse-manager-in-supporting-point-of-care-nurses-adoption-of-electronic-health-records-protocol-for-a-qualitative-research-study
#6
Gillian Strudwick, Richard G Booth, Ragnhildur I Bjarnadottir, Sarah Collins, Rani Srivastava
INTRODUCTION: An increasing number of electronic health record (EHR) systems have been implemented in clinical practice environments where nurses work. Findings from previous studies have found that a number of intended benefits of the technology have not yet been realised to date, partially due to poor system adoption among health professionals such as nurses. Previous studies have suggested that nurse managers can support the effective adoption and use of the technology by nurses. However, no known studies have identified what role nurse managers have in supporting technology adoption, nor the specific strategies that managers can employ to support their staff...
October 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025844/investigating-canadian-parents-hpv-vaccine-knowledge-attitudes-and-behaviour-a-study-protocol-for-a-longitudinal-national-online-survey
#7
Gilla K Shapiro, Samara Perez, Anila Naz, Ovidiu Tatar, Juliet R Guichon, Rhonda Amsel, Gregory D Zimet, Zeev Rosberger
INTRODUCTION: Human papillomavirus (HPV), a sexually transmitted infection, can cause anogenital warts and a number of cancers. To prevent morbidity and mortality, three vaccines have been licensed and are recommended by Canada's National Advisory Committee on Immunisation (for girls since 2007 and boys since 2012). Nevertheless, HPV vaccine coverage in Canada remains suboptimal in many regions. This study will be the first to concurrently examine the correlates of HPV vaccine decision-making in parents of school-aged girls and boys and evaluate changes in parental knowledge, attitudes and behaviours over time...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025843/preparing-the-prescription-a-review-of-the-aim-and-measurement-of-social-referral-programmes
#8
Emily S Rempel, Emma N Wilson, Hannah Durrant, Julie Barnett
OBJECTIVE: Our aim is to review, and qualitatively evaluate, the aims and measures of social referral programmes. Our first objective is to identify the aims of social referral initiatives. Our second objective is to identify the measures used to evaluate whether the aims of social referral were met. DESIGN: Literature review. BACKGROUND: Social referral programmes, also called social prescribing and emergency case referral, link primary and secondary healthcare with community services, often under the guise of decreasing health system costs...
October 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025429/updated-clinical-guidelines-experience-major-reporting-limitations
#9
Robin W M Vernooij, Laura Martínez García, Ivan Dario Florez, Laura Hildago Armas, Michiel H F Poorthuis, Melissa Brouwers, Pablo Alonso-Coello
BACKGROUND: The Checklist for the Reporting of Updated Guidelines (CheckUp) was recently developed. However, so far, no systematic assessment of the reporting of updated clinical guidelines (CGs) exists. We aimed to examine (1) the completeness of reporting the updating process in CGs and (2) the inter-observer reliability of CheckUp. METHODS: We conducted a systematic assessment of the reporting of the updating process in a sample of updated CGs using CheckUp. We performed a systematic search to identify updated CGs published in 2015, developed by a professional society, reporting a systematic review of the evidence, and containing at least one recommendation...
October 12, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29024416/review-article-a-systematic-review-of-emergency-department-incident-classification-frameworks
#10
REVIEW
Matthew Murray, Sally McCarthy
As in any part of the hospital system, safety incidents can occur in the ED. These incidents arguably have a distinct character, as the ED involves unscheduled flows of urgent patients who require disparate services. To aid understanding of safety issues and support risk management of the ED, a comparison of published ED specific incident classification frameworks was performed. A review of emergency medicine, health management and general medical publications, using Ovid SP to interrogate Medline (1976-2016) was undertaken to identify any type of taxonomy or classification-like framework for ED related incidents...
October 11, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29024343/dimensionality-and-internal-structure-of-the-colombian-version-of-the-inico-feaps-quality-of-life-scale
#11
M A Verdugo-Alonso, C P Henao-Lema, L Córdoba-Andrade, V B Arias González
BACKGROUND AND OBJECTIVE: Measuring quality of life (QoL) in people with intellectual disabilities (IDs) can help organisations and practitioners to implement evidence-based practices and develop person-centred planning and individualised supports. There is no reliable and valid instrument for assessing QoL in people with ID in Colombia. We investigated the internal structure of the Colombian version of the INICO-FEAPS scale and tested whether the scale identified the eight interrelated domains of the QoL conceptual framework originally described by...
October 10, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29024162/sexuality-and-individual-support-plans-for-people-with-intellectual-disabilities
#12
J M T Stoffelen, M A Herps, W H E Buntinx, D Schaafsma, G Kok, L M G Curfs
BACKGROUND: Sexual rights and sexuality are important aspects of quality of life, also for people with intellectual disabilities (IDs). However, providing support in this area to people with ID poses some challenges. In this study, the content of individual support plan (ISP) documents was analysed to determine the extent to which sexuality and sexual rights are addressed in part of the ISP documents. METHOD: Content analysis was carried out on a sample of 187 ISP documents from seven different service provider organisations in the Netherlands...
October 11, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29024067/evaluation-of-multiplex-real-time-pcr-for-identifying-dermatophytes-in-clinical-samples-a-multicentre-study
#13
Shany Sherman, Maya Goshen, Orit Treigerman, Keren Ben-Zion, Marie-Jeanne Carp, Noam Maisler, Inbal Binsky Ehrenreich, Aviva Kimchi, Sara Lifshitz, Gill Smollan, Batya Davidovici, Michael David, Emmilia Hodak, Rina Segal
BACKGROUND: The gold-standard method for dermatophyte identification involves direct microscopy and culture, which have inherent shortcomings. Only few molecular methods have been standardised for routine clinical work. OBJECTIVES: To develop and test a platform for identifying the most common dermatophytes in Israel using multiplex real-time polymerase chain reaction (RT-PCR). METHODS: Specific primers were designed for the multiplex system (LightCycler 480) according to known cultures and validated by reference isolates...
October 12, 2017: Mycoses
https://www.readbyqxmd.com/read/29024032/que-faire-a-bioeconomy-and-solar-energy-institute-at-italy-s-research-council-in-the-context-of-the-global-transition-to-the-solar-economy
#14
Mario Pagliaro, Francesco Meneguzzo
Driven by insight for which new research and education requires new institutional organisation, and drawing on two decades of research and educational efforts, we devise the profile and activities of a new bioeconomy and solar energy institute at Italy's Research Council. We further articulate the institute's activities suggesting avenues on how to deploy sound and giving more useful research, education and policy advice in these crucial fields for making tomorrow's common development sustainable. The outcomes of the study are of general interest, because the transition to a solar economy is of intrinsic global nature and the challenges involved are similar in many countries...
October 12, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29024004/shortening-gestational-age-at-term-and-organisation-of-birth-care-in-the-czech-republic
#15
Martina Štípková
A trend of the shortening duration of pregnancies carried to term has been observed in several countries and represents a growing public health concern. This paper describes the trend in the Czech Republic and shows its relation to the changing demographic structure of mothers and the organisation of maternity care. Data from the birth register are used and supplemented with information about the capacity of maternity care (number of beds at maternity clinics, number of obstetricians and midwives). Logistic regression is used to estimate the odds of 37 to 39 vs 40+ completed weeks of gestation...
October 10, 2017: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29023740/surveillance-and-monitoring-of-oral-health-in-elderly-people
#16
Hideo Miyazaki, Judith A Jones, Eugenio D Beltrán-Aguilar
Continued ageing of the global population is expected to pose significant challenges to maintaining optimum lifelong health in individuals and populations. Oral health is an essential element of general health and quality of life throughout an individual's life course, yet it is often neglected in integrated approaches to general health promotion. Surveillance and monitoring systems are essential for developing oral health policy and strategy at both national and community levels. As major oral diseases, dental caries and periodontal diseases are core indicators for surveillance at every stage of life...
September 2017: International Dental Journal
https://www.readbyqxmd.com/read/29022862/future-research-to-underpin-successful-peste-des-petits-ruminants-virus-pprv-eradication
#17
Michael D Baron, Bouna Diop, Felix Njeumi, Brian J Willett, Dalan Bailey
Peste des petits ruminants virus (PPRV) is a significant pathogen of small ruminants and is prevalent in much of Africa, the Near and Middle East and Asia. Despite the availability of an efficacious and cheap live-attenuated vaccine, the virus has continued to spread, with its range stretching from Morocco in the west to China and Mongolia in the east. Some of the world's poorest communities rely on small ruminant farming for subsistence and the continued endemicity of PPRV is a constant threat to their livelihoods...
October 12, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/29022779/short-term-surgical-outcomes-and-patient-quality-of-life-between-robotic-and-laparoscopic-extralevator-abdominoperineal-excision-for-adenocarcinoma-of-the-rectum
#18
D Kamali, A Reddy, S Imam, K Omar, A Jha, M Jha
Introduction Some studies advocate a laparoscopic extralevator abdominoperineal excision (l-ELAPE) approach for low rectal cancer. The da Vinci™ robot (r-ELAPE) technique has potential to overcome some limitations of l-ELAPE, such as reduction of the learning curve and more precise tissue handling. It is unknown whether this approach results in improved surgical or quality of life outcomes compared with l-ELAPE. This study aimed to address this issue. Methods Consecutive patients having undergone either robotic or laparoscopic ELAPE for adenocarcinoma were studied...
September 15, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29021983/an-integrated-framework-for-process-driven-model-construction-in-disease-ecology-and-animal-health
#19
REVIEW
Rebecca Mancy, Patrick M Brock, Rowland R Kao
Process models that focus on explicitly representing biological mechanisms are increasingly important in disease ecology and animal health research. However, the large number of process modelling approaches makes it difficult to decide which is most appropriate for a given disease system and research question. Here, we discuss different motivations for using process models and present an integrated conceptual analysis that can be used to guide the construction of infectious disease process models and comparisons between them...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29021838/qualitative-analysis-of-parkinson-s-disease-information-on-social-media-the-case-of-youtube%C3%A2
#20
Ibrahim Saleh Al-Busaidi, Tim J Anderson, Yassar Alamri
INTRODUCTION: There is a paucity of data pertaining to the usefulness of information presented on social media platforms on chronic neuropsychiatric conditions such as Parkinson's disease (PD). The aim of this study was to examine the quality of YouTube™ videos that deliver general information on PD and the availability and design of instructional videos addressing the caregiving role in PD. METHODS: YouTube™ was searched using the keyword "Parkinson's disease" for relevant videos...
September 2017: EPMA Journal
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