B N Tate, M M Deys, F A Gutierrez-Oviedo, A D Ferguson, Y Zang, B J Bradford, P Deme, N J Haughey, J W McFadden
Lysophosphatidylcholine (LPC) is immunomodulatory in non-ruminants; however, the actions of LPC on immunity in cattle are undefined. Our objective was to study the effects of LPC administration on measures of immunity, liver health, and growth in calves. Forty-six healthy Holstein heifer calves (age 7 ± 3 d) were randomly assigned to 1 of 4 treatments (n = 10 to 11 calves/treatment): a milk replacer diet unsupplemented with lecithin in the absence (CON) or presence of subcutaneous (s.c.) administered mixed (mLPC; 69% LPC-16:0, 25% LPC-18:0, 6% other) or pure (pLPC; 99% LPC-18:0) LPC, or a milk replacer diet supplemented with 3% lecithin enriched in lysophospholipids containing LPC in the absence of s...
December 13, 2023: Journal of Dairy Science