keyword
https://read.qxmd.com/read/33588454/screening-for-cancer-in-patients-with-acute-venous-thromboembolic-disease
#21
REVIEW
Marc Blondon
Active cancer causes approximately 25% of all acute events of venous thromboembolism (VTE). While most of the cancer diagnoses are known or clinically apparent at the time of VTE, care providers and patients may be worried about the 3 to 8% risk of occult cancer occurring in the year after VTE. Several studies have compared limited to extensive cancer screening after acute VTE, especially with the addition of abdominal computed tomography (CT) or whole-body PET-CT, with the hope to shorten the time to cancer diagnosis and lead to less advanced cancer stages...
February 2021: Hämostaseologie
https://read.qxmd.com/read/33560973/a-piercing-diagnosis-occult-foreign-body-as-the-cause-of-acute-inguinal-pain
#22
JOURNAL ARTICLE
Coral Bays-Muchmore, Deion T Sims, Joel A Gross, Jonathan S Ilgen
CASE PRESENTATION: A 35-year-old woman presented to the emergency department with severe right inguinal pain. Her medical history was non-contributory and there was no known trauma or injury to the region. Amid concern for an incarcerated inguinal hernia, a computed tomography was obtained revealing a linear foreign body (FB) lateral to the femoral vessels. The FB was removed without complication at bedside and found to be a beading needle likely occultly lodged three days prior. DISCUSSION: Occult inguinal FBs are rare but can lead to deep venous thrombosis or pulmonary embolism if in or near vessels...
February 2021: Clinical Practice and Cases in Emergency Medicine
https://read.qxmd.com/read/33342745/occult-deep-vein-thrombosis-in-lower-limb-trauma-requiring-microsurgical-reconstruction-a-retrospective-cohort-study
#23
JOURNAL ARTICLE
Charlotte L Bendon, Alexandra Crick
BACKGROUND: Delayed microsurgical reconstruction of lower extremity trauma is associated with increased risk of free flap loss, frequently following failure of the venous anastomosis. This has been attributed to thrombocytosis, but occult deep vein thrombosis (DVT) may contribute to this risk. METHODS: We performed a retrospective cohort study of consecutive patients presenting to our service with lower limb injuries requiring microsurgical reconstruction between 2013 and 2017, and examined venous Duplex ultrasound reports, operation notes and free flap outcomes...
April 2021: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/33138640/lung-adenocarcinoma-presenting-as-multiple-thromboembolic-events-a-case-report-and-review-of-the-literature
#24
JOURNAL ARTICLE
Gliceida M Galarza Fortuna, Anita Singh, Adam Jacobs, Israel Ugalde
Patients with malignancy may present with significant thromboembolic complications including deep vein thrombosis (DVT), pulmonary embolism, arterial thrombosis, nonbacterial thrombotic endocarditis, and stroke due to abnormal coagulation cascades. Although these events are typically recognized later in the disease process, complications of a hypercoagulable state can rarely present as the first manifestation of an occult malignancy. We report a case of a young male who was ultimately found to have an aggressive form of lung adenocarcinoma after the initial presentation of multiple thromboembolic events...
January 2020: Journal of Investigative Medicine High Impact Case Reports
https://read.qxmd.com/read/32673617/severe-acute-respiratory-syndrome-coronavirus-2-infection-and-thrombosis-phlegmasia-cerulea-dolens-presenting-with-venous-gangrene-in-a-child
#25
Gautam K Visveswaran, Kavita Morparia, Shalu Narang, Cindy Sturt, Michael Divita, Brett Voigt, Amer Hawatmeh, Derrick McQueen, Marc Cohen
A 12-year-old girl with severe acute respiratory syndrome coronavirus 2 infection presented as phlegmasia cerulea dolens with venous gangrene. Emergent mechanical thrombectomy was complicated by a massive pulmonary embolism and cardiac arrest, for which extracorporeal cardiopulmonary resuscitation and therapeutic hypothermia were used. Staged ultrasound-assisted catheter-directed thrombolysis was used for treatment of bilateral pulmonary emboli and the extensive lower extremity deep vein thrombosis while the patient received extracorporeal membrane oxygenation support...
November 2020: Journal of Pediatrics
https://read.qxmd.com/read/32485855/novel-diagnostic-options-without-contrast-media-or-radiation-triggered-angiography-non-contrast-enhanced-sequence-magnetic-resonance-imaging-in-treating-different-leg-venous-diseases
#26
JOURNAL ARTICLE
Chien-Wei Chen, Yuan-Hsi Tseng, Chien-Chiao Lin, Chih-Chen Kao, Min Yi Wong, Bor-Shyh Lin, Yao-Kuang Huang
OBJECTIVES: Venous diseases in the lower extremities long lacked an objective diagnostic tool prior to the advent of the triggered angiography non-contrast-enhanced (TRANCE) technique. METHODS: An observational study with retrospective data analysis. MATERIALS: Between April 2017 and June 2019, 66 patients were evaluated for venous diseases through TRANCE-magnetic resonance imaging (MRI) and were grouped according to whether they had occlusive venous (OV) disease, a static venous ulcer (SU), or symptomatic varicose veins (VV)...
May 29, 2020: Diagnostics
https://read.qxmd.com/read/32473551/non-hodgkin-s-lymphoma-presenting-as-deep-venous-thrombosis-a-case-report-with-literature-review
#27
Okba F Ahmed, Fahmi H Kakamad, Abdulwahid M Salih, Mohammed Q Mustafa, Shvan H Mohammed
INTRODUCTION: Idiopathic deep venous thrombosis is a relatively common clinical finding. The aim of this article is to report and discuss a case of lymphoma presented as DVT in line with SCARE guidelines with brief literature review. CASE REPORT: A 19-year-old male presented with right lower limb swelling for two week duration. Examination showed pitting leg edema with warm tense calf. Hematological investigations showed lymphopaenia. Duplex ultrasound showed DVT of right common femoral vein with inguinal lymphadenopathy...
2020: International Journal of Surgery Case Reports
https://read.qxmd.com/read/32308583/nonbacterial-thrombotic-endocarditis-and-widespread-skin-necrosis-in-newly-diagnosed-lung-adenocarcinoma
#28
Katerina Zakka, Patrick Zakka, Amir Davarpanah, Nikoloz Koshkelashvili, Mehmet A Bilen, Taofeek Owonikoko, Bassel El-Rayes, Mehmet Akce
Nonbacterial thrombotic endocarditis (NBTE) is a rare entity most commonly diagnosed postmortem with rates in autopsy series ranging from 0.9 to 1.6%. A 63-year-old female with past medical history of hypertension and mitral valve prolapse presented to the hospital with shortness of breath, headache, and necrotic skin lesions on her hands and feet. Computed tomography (CT) scan of her chest demonstrated a pulmonary embolus in the right lower lung segmental artery and right upper lobe lobar to segmental pulmonary artery, a mass-like consolidation in the left upper lung field impeding the hilum...
January 2020: Case Reports in Oncology
https://read.qxmd.com/read/31847822/evaluation-of-venous-pathology-of-the-lower-extremities-with-triggered-angiography-non-contrast-enhanced-magnetic-resonance-imaging
#29
JOURNAL ARTICLE
Yao-Kuang Huang, Yuan-Hsi Tseng, Chih-Hung Lin, Yuan-Hsiung Tsai, Yin-Chen Hsu, Shih-Chung Wang, Chien-Wei Chen
BACKGROUND: To explore the diagnostic performance of triggered angiography non-contrast-enhanced magnetic resonance imaging (TRANCE-MRI) for the evaluation of venous pathology of the lower extremity. METHODS: This was a single-centre prospective cohort study of 25 patients with suspected venous disease in the lower extremities. Each patient received Doppler ultrasonography (for venous evaluation) before the scheduled TRANCE-MRI (for venous and arterial evaluations) on a 1...
December 17, 2019: BMC Medical Imaging
https://read.qxmd.com/read/31669473/high-prevalence-and-mortality-associated-with-upper-extremity-deep-venous-thrombosis-in-hospitalized-patients-at-a-tertiary-care-center
#30
JOURNAL ARTICLE
Rae S Rokosh, Neel Ranganath, Patricia Yau, Caron Rockman, Mikel Sadek, Todd Berland, Glenn Jacobowitz, Jeff Berger, Thomas S Maldonado
OBJECTIVE: Upper extremity deep venous thrombosis (UEDVT) and its associated complications are increasing in incidence, but management strategies are largely derived from experience treating lower extremity deep venous thrombosis (LEDVT). The purpose of this study was to examine our single institution's experience with in-hospital venous thromboembolism (VTE), specifically the characteristics and outcomes of the UEDVT population as it compares to LEDVT.∗ MATERIAL AND METHODS: This is a single tertiary care center retrospective cohort study of all consecutive inpatients diagnosed with acute VTE from June 2015 to December 2015...
October 24, 2019: Annals of Vascular Surgery
https://read.qxmd.com/read/31632334/muscular-tuberculosis-a-new-case-and-a-review-of-the-literature
#31
Yanping Zeng, Yin Liu, Yanchun Xie, Jingjing Liang, Jiabing Kuang, Zuneng Lu, Yu Zhou
Objective: To investigate the clinical manifestations, underlying diseases, pathological features, and therapeutic responses in patients with muscular tuberculosis (MT), which is rare and often misdiagnosed in clinical practice. Methods: This study describes a rare MT case that was recently diagnosed in our department. Additionally, 18 other MT cases retrieved from the PubMed database from 2,000 to date are included in this study. The clinical manifestations, areas of residence, underlying diseases, laboratory test results, pathology results, and outcomes of the patients were recorded and analyzed...
2019: Frontiers in Neurology
https://read.qxmd.com/read/30995001/cardiovascular-disease-lower-extremity-deep-venous-thrombosis
#32
JOURNAL ARTICLE
Michael Braun, David Kassop
Risk factors for deep venous thrombosis (DVT) include immobility, recent or current hospitalization, recent surgery, recent infection, and cancer. Patients with suspected venous thromboembolism should be evaluated with the Wells score or modified Wells score (which adds a previous DVT) to determine the likelihood of DVT. A low or moderate probability score and a normal D-dimer test result exclude DVT. If the score indicates that DVT is likely, patients should undergo Doppler ultrasonography (US). If US reveals DVT in a proximal (ie, in the knee or above) vein, anticoagulation should be started unless contraindicated...
April 2019: FP Essentials
https://read.qxmd.com/read/30921267/insertable-cardiac-monitor-detection-of-silent-atrial-fibrillation-in-candidates-for-percutaneous-patent-foramen-ovale-closure
#33
JOURNAL ARTICLE
Paolo Scacciatella, Marcella Jorfida, Lorenza M Biava, Ilaria Meynet, Domenica Zema, Fabrizio D'Ascenzo, Christian Pristipino, Paolo Cerrato, Carla Giustetto, Fiorenzo Gaita
AIM: An underlying atrial vulnerability or a preexisting misdiagnosed atrial fibrillation in some patients who are candidates for patent foramen ovale (PFO) closure may lead to an unnecessary percutaneous intervention. The aim of this work was to define paroxysmal atrial fibrillation rate, through a 6-month insertable loop-recorder monitoring, in patients over 55 years old with cryptogenic stroke and PFO. METHODS: PFO closure criteria: significant right-to-left shunt and at least one high-risk feature (permanent right-to-left shunt, atrial septal aneurysm, prominent Eustachian valve, recurrent brain ischemia, previous deep vein thrombosis, thrombophilia)...
May 2019: Journal of Cardiovascular Medicine
https://read.qxmd.com/read/30780008/relationship-between-type-of-unprovoked-venous-thromboembolism-and-cancer-location-an-individual-patient-data-meta-analysis
#34
JOURNAL ARTICLE
L Jara-Palomares, N van Es, J M Praena-Fernandez, G Le Gal, H M Otten, P Robin, A Piccioli, R Lecumberri, P Religa, V Rieu, M Rondina, M Beckers, P Prandoni, P Y Salaun, M Di Nisio, P M Bossuyt, N Kraaijpoel, H R Büller, M Carrier
BACKGROUND: Unprovoked venous thromboembolism (VTE) may be the first manifestation of an underlying cancer. We aimed to assess the period prevalence of occult cancer detection stratified by VTE location (deep vein thrombosis [DVT], pulmonary embolism [PE] or both) and the anatomical relationship between occult cancer and VTE. METHODS: Post-hoc analysis of a systematic review and individual patient data meta-analysis of adults with unprovoked VTE with at least 12 months of follow-up...
February 13, 2019: Thrombosis Research
https://read.qxmd.com/read/30448323/occult-left-common-iliac-vein-compression-increases-postoperative-venous-thromboembolism-risk-following-total-hip-arthroplasty
#35
JOURNAL ARTICLE
Michael A Bergen, Kevin C Wall, Charles Y Kim, Grant E Garrigues
BACKGROUND: Left common iliac vein (LCIV) compression by the right or left common iliac artery (RCIA, LCIA) is known to cause venous thromboembolism (VTE), but the extent to which occult LCIV compression synergizes with lower extremity orthopedic surgery is unknown. We hypothesize that occult LCIV compression is associated with increased VTE risk following total hip or knee arthroplasty (THA, TKA). METHODS: This case-control study involves all patients at our institution who underwent primary or revision THA or TKA from 2009 to 2017 who had computed tomography or magnetic resonance imaging of the abdomen or pelvis available preoperatively...
February 2019: Journal of Arthroplasty
https://read.qxmd.com/read/30264545/retinal-vein-thrombosis-and-risk-of-occult-cancer-a-nationwide-cohort-study
#36
JOURNAL ARTICLE
Anette Tarp Hansen, Katalin Veres, Paolo Prandoni, Kasper Adelborg, Henrik Toft Sørensen
BACKGROUND: Retinal vein thrombosis has in case reports been reported a clinical sign of cancer, especially hematological cancer. However, it is unclear whether retinal vein thrombosis is a marker of underlying cancer, as is the case for deep venous thrombosis and pulmonary embolism. We investigated the risk of occult cancer in patients with retinal vein thrombosis. METHODS: A nationwide population-based cohort study in Denmark on all patients diagnosed with a retinal vein thrombosis during 1994 and 2013...
November 2018: Cancer Medicine
https://read.qxmd.com/read/30114315/prospective-implementation-of-a-standardized-screening-protocol-for-deep-venous-thrombosis-in-abdominal-surgical-oncology-patients
#37
JOURNAL ARTICLE
Andrew J Sinnamon, Jason K C Tong, Elizabeth A Bailey, Caitlin Brown, Latesha Colbert, Shannon Murray, Benjamin M Jackson, Robert E Roses
BACKGROUND AND OBJECTIVES: Venous thromboembolism (VTE) remains a major cause of perioperative morbidity and mortality despite implementation of prophylaxis guidelines. We sought to identify risk factors for occult deep venous thrombosis (DVT) following abdominal surgery for cancer and measure the clinical impact of a prospectively implemented standardized postoperative DVT screening protocol. METHODS: Patients undergoing abdominal surgery for malignant indication were screened with early postoperative lower extremity duplex to identify DVT...
September 2018: Journal of Surgical Oncology
https://read.qxmd.com/read/29849283/occult-iliac-deep-vein-thrombosis-in-second-trimester-pregnancy-clues-on-bedside-ultrasound
#38
Roopa Avula, Michael Niemann, Nicole Dorinzi, Kristine Robinson, Melinda Sharon, Joseph Minardi
Isolated pelvic deep vein thromboses (DVT) are rare and difficult to diagnose, but they are more common in pregnant women and carry an increased risk of embolization. Pulmonary embolism is the most common non-obstetric cause of death in pregnancy. Compression ultrasound is the first-line imaging test for suspected lower extremity DVT, but it cannot usually aid in directly visualizing or easily diagnosing isolated pelvic DVT. Nonetheless, point-of-care ultrasound (POCUS) may provide valuable clues to help rule in pelvic DVT and expedite initiation of anticoagulant therapy...
August 2017: Clinical Practice and Cases in Emergency Medicine
https://read.qxmd.com/read/29567899/autopsy-findings-in-an-atypical-case-of-occult-massive-fatal-pulmonary-embolism-in-a-backdrop-of-hyperhomocysteinemia
#39
Pratibha Misra, Arijit Kumar Ghosh, Aneeta Jassar
A 43-year-old apparently healthy male presented with fever and presyncope. He was suspected to have massive pulmonary thromboembolism based on the clinico-biochemical profile. Despite aggressive thrombolytic therapy, he succumbed to his illness within 12 h of admission. Postmortem examination showed massive pulmonary thromboembolism and hyperhomocysteinemia with low high-density lipoproteins (HDL) cholesterol with antemortem blood sample. Herein, we report autopsy findings in a rare case of a young male with occult massive pulmonary thromboembolism without deep vein thrombosis, who had an atypical clinical presentation and was found to have underlying hyperhomocysteinemia and decreased HDLc...
January 2018: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/29524978/t4-urothelial-carcinoma-in-undiagnosed-closed-bladder-exstrophy-in-a-post-menopausal-female
#40
JOURNAL ARTICLE
Brian J McArdle, Patricia Vidal, Sarah P Psutka, Courtney M P Hollowell
It is rare to see an adult presenting with exstrophy of the bladder. Malignant conversion in exstrophy occurs in 4%, with adenocarcinoma as the most common histopathology. We report the first case of metastatic high grade urothelial carcinoma with squamous and sarcomatoid differentiation arising from undiagnosed, closed bladder exstrophy in a female at advanced age with associated bilateral deep vein thrombosis and clot retention. The patient developed clinical progression of disease despite neoadjuvant gemcitabine-cisplatin and salvage (or palliative) radiotherapy...
February 2018: Canadian Journal of Urology
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