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Clotilde Muller, Dorothée Bazin Kara, Marion Fourtage, Julien Ott, Thierry Krummel, Olivier Imhoff, Antoine Garstka, Sarah Richter, Isabelle Kolb, Anne-Laure Faller, Philippe Petit-Jean, Clotilde Kiener, Farideh Alenabi, Henriette Sissoko, Émilie Léon, François Chantrel, Yves Dimitrov, Thierry Hannedouche
Leaflets inside drug boxes are complex and often poorly understood. Patients consulting in nephrology are mostly old and often suffer from multiple comorbidities. As so, they are often subject to various contra-indications and drug interactions. This paper aims to evaluate if patients actually read leaflets or other medical information on others medias such as Internet and whether this could, potentially, interfere with their observance. Results showed that leaflets were read by 65.1% of patients, leading to 12% of withdrawal or not taking drugs...
September 27, 2016: Néphrologie & Thérapeutique
Raman Kumar, Ana Nunes Barata, Mayara Floss
This opinion paper is a collaborative effort describing recent developments in primary care education in three different countries; representing diverse socioeconomic and political systems. The authors describe their respective perspectives from the point of student (Brazil), trainee (Portugal) and young doctor (India). The section on Brazil focuses on the response of the medical education system to the developments before and after political reforms, leading to creation of the Unified Health System. The Indian experience focuses on the challenges faced by recently qualified doctors and ongoing debates about the medical education system in a highly populated but rapidly growing economy...
September 2016: Education for Primary Care
Pavani Yashodha De Silva, Gamage Upeksha Ganegoda
With the exponential growth in the capacity of information generated and the emerging need for data to be stored for prolonged period of time, there emerges a need for a storage medium with high capacity, high storage density, and possibility to withstand extreme environmental conditions. DNA emerges as the prospective medium for data storage with its striking features. Diverse encoding models for reading and writing data onto DNA, codes for encrypting data which addresses issues of error generation, and approaches for developing codons and storage styles have been developed over the recent past...
2016: BioMed Research International
Marcela Tiburcio, Ma Asunción Lara, Araceli Aguilar Abrego, Morise Fernández, Nora Martínez Vélez, Alejandro Sánchez
BACKGROUND: The development of Web-based interventions for substance abuse in Latin America is a new field of interest with great potential for expansion to other Spanish-speaking countries. OBJECTIVE: This paper describes a project aimed to develop and evaluate the usability of the Web-based Help Program for Drug Abuse and Depression (Programa de Ayuda para Abuso de Drogas y Depresión, PAADD, in Spanish) and also to construct a systematic frame of reference for the development of future Web-based programs...
September 29, 2016: JMIR Mental Health
James Reavell, Qulsom Fazil
BACKGROUND: With an increasing number of refugees migrating across continents, the crisis is very apparent. AIM: A literature review of patterns, risk factors and effects of post-traumatic stress disorder (PTSD) and depression in refugee minors was carried out involving those who have resettled in different developed countries. METHODS: Papers were narrowed down by reading the abstracts and methods to ascertain whether the refugee children had resettled in developed countries and to ensure that they had not just been internally displaced...
September 29, 2016: Journal of Mental Health
Richard D Beger, Warwick Dunn, Michael A Schmidt, Steven S Gross, Jennifer A Kirwan, Marta Cascante, Lorraine Brennan, David S Wishart, Matej Oresic, Thomas Hankemeier, David I Broadhurst, Andrew N Lane, Karsten Suhre, Gabi Kastenmüller, Susan J Sumner, Ines Thiele, Oliver Fiehn, Rima Kaddurah-Daouk
INTRODUCTION BACKGROUND TO METABOLOMICS: Metabolomics is the comprehensive study of the metabolome, the repertoire of biochemicals (or small molecules) present in cells, tissues, and body fluids. The study of metabolism at the global or "-omics" level is a rapidly growing field that has the potential to have a profound impact upon medical practice. At the center of metabolomics, is the concept that a person's metabolic state provides a close representation of that individual's overall health status...
2016: Metabolomics: Official Journal of the Metabolomic Society
Kahraman Ulker, Yuksel Kivrak
BACKGROUND: Crowded hospital outpatient clinics and endless waiting lines that make patients feel overlooked tend to exaggerate patients' anxiety levels. In addition, fear of pain, shyness, religious and traditional thoughts, women's sexual role in society, and previous information and experience also contribute to people's anxiety levels with regard to gynecologic examination. OBJECTIVES: We aimed to analyze the effect of specific information about gynecologic examination on anxiety levels of women applying to gynecology clinics...
June 2016: Iranian Red Crescent Medical Journal
P M van der Kraan
OBJECTIVE: Osteoarthritis (OA) is the most common joint disease but an effective pharmacological therapy has not been developed yet. To identify targets for treatment and ways to interfere with OA development and progression both spontaneous and induced OA models are still needed. In this narrative review it is discussed what variables can be identified that lead to variation in OA animal model studies. DESIGN: Literature was screened (Pubmed) with the following terms; OA animal models in combination with species, age, strain, gender/sex, housing, diet, fighting, circadian rhythm, transgenic...
September 9, 2016: Osteoarthritis and Cartilage
Sandeep B Bavdekar
For presenting the study results, authors need to choose from one of the three formats: text, tables and graphs. The underlying consideration of any author while making the choice is to ensure that readers find it easy to understand, to assist the author present data in a way that would catch the reader's eye, hold his interest and enhance his understanding. The choice should, therefore, be based on the advantages and limitations of each of these formats. Most of the observations are reported in textual format...
October 2015: Journal of the Association of Physicians of India
Xiaodong Cui, Jia Meng, Shaowu Zhang, Manjeet K Rao, Yidong Chen, Yufei Huang
BACKGROUND: The recent advent of the state-of-art high throughput sequencing technology, known as Methylated RNA Immunoprecipitation combined with RNA sequencing (MeRIP-seq) revolutionizes the area of mRNA epigenetics and enables the biologists and biomedical researchers to have a global view of N (6)-Methyladenosine (m(6)A) on transcriptome. Yet there is a significant need for new computation tools for processing and analysing MeRIP-Seq data to gain a further insight into the function and m(6)A mRNA methylation...
2016: BMC Genomics
Jörn Conell, Rita Bauer, Tasha Glenn, Martin Alda, Raffaella Ardau, Bernhard T Baune, Michael Berk, Yuly Bersudsky, Amy Bilderbeck, Alberto Bocchetta, Letizia Bossini, Angela Marianne Paredes Castro, Eric Yat Wo Cheung, Caterina Chillotti, Sabine Choppin, Maria Del Zompo, Rodrigo Dias, Seetal Dodd, Anne Duffy, Bruno Etain, Andrea Fagiolini, Julie Garnham, John Geddes, Jonas Gildebro, Ana Gonzalez-Pinto, Guy M Goodwin, Paul Grof, Hirohiko Harima, Stefanie Hassel, Chantal Henry, Diego Hidalgo-Mazzei, Vaisnvy Kapur, Girish Kunigiri, Beny Lafer, Chun Lam, Erik Roj Larsen, Ute Lewitzka, Rasmus Licht, Anne Hvenegaard Lund, Blazej Misiak, Patryk Piotrowski, Scott Monteith, Rodrigo Munoz, Takako Nakanotani, René E Nielsen, Claire O'Donovan, Yasushi Okamura, Yamima Osher, Andreas Reif, Philipp Ritter, Janusz K Rybakowski, Kemal Sagduyu, Brett Sawchuk, Elon Schwartz, Ângela Miranda Scippa, Claire Slaney, Ahmad Hatim Sulaiman, Kirsi Suominen, Aleksandra Suwalska, Peter Tam, Yoshitaka Tatebayashi, Leonardo Tondo, Eduard Vieta, Maj Vinberg, Biju Viswanath, Julia Volkert, Mark Zetin, Iñaki Zorrilla, Peter C Whybrow, Michael Bauer
BACKGROUND: Information seeking is an important coping mechanism for dealing with chronic illness. Despite a growing number of mental health websites, there is little understanding of how patients with bipolar disorder use the Internet to seek information. METHODS: A 39 question, paper-based, anonymous survey, translated into 12 languages, was completed by 1222 patients in 17 countries as a convenience sample between March 2014 and January 2016. All patients had a diagnosis of bipolar disorder from a psychiatrist...
December 2016: International Journal of Bipolar Disorders
Jing Liao, Jonathan P Winickoff, Guangmin Nong, Kaiyong Huang, Li Yang, Zhiyong Zhang, Abu S Abdullah
BACKGROUND: Secondhand smoke (SHS) exposure of children due to parental tobacco use is a particularly prevalent health issue and is associated with adverse health outcomes. Following the US Clinical Practice guidelines, pediatricians in the United States deliver 5A's (ask, advise, assess, assist, and arrange) counseling to smoking parents which has proven to be effective. We examined Chinese pediatricians' adherence to the clinical practice guidelines for smoking cessation (i.e. 5A's counseling practices) with smoking parents, and identified factors associated with these practices...
2016: BMC Pediatrics
Diane Murray, Cathy Sedgeworth, Moira Kinnear, Lesley Diack
AIM: To gather opinions from doctors and pharmacists to improve the design of the PICU MR form generated by the electronic prescribing and clinical notes system to support transfer of care from PICU to downstream wards that use paper systems. METHOD: A purposive sample of 10 forms covering a comprehensive range of medication information common to PICU patients was selected from practice between March 2014 and May 2014. Pharmacists (n=7) and doctors (n=9) who received these forms on downstream wards were invited to participate in semi-structured one-to-one interviews (n=20) with the PICU pharmacist within 48 hrs of receipt to explore their views about the form...
September 2016: Archives of Disease in Childhood
Jacqueline Laures-Gore, Tiffany McCusker, Leila L Hartley
PURPOSE: Descriptions of speech-language interventions addressing the unique aspects of aphasia in adolescence appear to be nonexistent. The current paper presents the case of a male adolescent who experienced a stroke with resultant aphasia and the speech and language therapy he received. Furthermore, we discuss the issues that are unique to an adolescent with aphasia and how they were addressed with this particular patient. METHODS: Traditional language and apraxia therapy was provided to this patient with inclusion of technology and academic topics...
August 18, 2016: Disability and Rehabilitation
Sonia Hines, Joanne Ramsbotham, Fiona Coyer
BACKGROUND: Despite the importance of research literacy for nurses, many nurses report feeling unable to effectively read and understand research, which in turn results in lower research utilization in practice. Nurses themselves identify poor experiences with trying to understand and use research as factors that contribute to a reluctance to utilize research. This reluctance often leads nurses to seek other sources of information, such as colleagues, instead. OBJECTIVES: The objective of this review was to identify the effectiveness of research literacy interventions on the research literacy of registered nurses...
February 2016: JBI Database of Systematic Reviews and Implementation Reports
Matteo Comin, Michele Schimd
BACKGROUND: Sequencing technologies are generating enormous amounts of read data, however assembly of genomes and metagenomes remain among the most challenging tasks. In this paper we study the comparison of genomes and metagenomes only based on read data, using word counts statistics called alignment-free thus not requiring reference genomes or assemblies. Quality scores produced by sequencing platforms are fundamental for various analyses, moreover future-generation sequencing platforms, will produce longer reads but with error rate around 15 %...
2016: BMC Medical Genomics
Osman Ratib, Nicolas Roduit, Dechen Nidup, Gerard De Geer, Antoine Rosset, Antoine Geissbuhler
UNLABELLED: This paper reports the design and implementation of an innovative and cost-effective imaging management infrastructure suitable for radiology centres in emerging countries. It was implemented in the main referring hospital of Bhutan equipped with a CT, an MRI, digital radiology, and a suite of several ultrasound units. They lacked the necessary informatics infrastructure for image archiving and interpretation and needed a system for distribution of images to clinical wards...
October 2016: Insights Into Imaging
Nadine A Kasparian, Shab Mireskandari, Phyllis N Butow, Mbathio Dieng, Anne E Cust, Bettina Meiser, Kristine Barlow-Stewart, Scott Menzies, Graham J Mann
PURPOSE: People with melanoma often report pervasive fears about cancer recurrence, unmet information needs, and difficulties accessing psychological care. Interventions addressing the supportive care needs of people with melanoma are rare, and needs are often overlooked. The study evaluated a newly developed, evidence-based, psycho-educational resource for people with melanoma. METHODS: The evaluation study comprised three groups: adults at high risk of new primary disease due to multiple previous melanomas or one melanoma and dysplastic nevus syndrome (DNS), adults at moderate risk due to one previous melanoma and no DNS, and health professionals involved in melanoma care...
July 27, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Elsa A Kirchner, Su K Kim, Marc Tabie, Hendrik Wöhrle, Michael Maurus, Frank Kirchner
Advanced man-machine interfaces (MMIs) are being developed for teleoperating robots at remote and hardly accessible places. Such MMIs make use of a virtual environment and can therefore make the operator immerse him-/herself into the environment of the robot. In this paper, we present our developed MMI for multi-robot control. Our MMI can adapt to changes in task load and task engagement online. Applying our approach of embedded Brain Reading we improve user support and efficiency of interaction. The level of task engagement was inferred from the single-trial detectability of P300-related brain activity that was naturally evoked during interaction...
2016: Frontiers in Human Neuroscience
Patrick Cheong-Iao Pang, Karin Verspoor, Jon Pearce, Shanton Chang
Despite the fact that search engines are the primary channel to access online health information, there are better ways to find and explore health information on the web. Search engines are prone to problems when they are used to find health information. For instance, users have difficulties in expressing health scenarios with appropriate search keywords, search results are not optimised for medical queries, and the search process does not account for users' literacy levels and reading preferences. In this paper, we describe our approach to addressing these problems by introducing a novel design using a slider-based user interface for discovering health information without the need for precise search keywords...
2016: Studies in Health Technology and Informatics
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