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https://www.readbyqxmd.com/read/28933994/decision-making-for-people-living-with-dementia-by-their-carers-at-the-end-of-life-a-rapid-scoping-review
#1
Sue Barker, Mary Lynch, Jane Hopkinson
BACKGROUND: There are an increasing number of people living with dementia, as well as an expectation that care decisions are made collaboratively with those with the disease entering the end stage and their families. This has increased the burden on family carers. AIM: To explore the evidence on the decisional support needs of informal carers of people with end-stage dementia. DESIGN: A rapid scoping review was undertaken of peer-reviewed publications between 2000 and 2016, which included all health-care settings and the person's own home...
September 2, 2017: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/28932018/measuring-orthographic-transparency-and-morphological-syllabic-complexity-in-alphabetic-orthographies-a-narrative-review
#2
REVIEW
Elisabeth Borleffs, Ben A M Maassen, Heikki Lyytinen, Frans Zwarts
This narrative review discusses quantitative indices measuring differences between alphabetic languages that are related to the process of word recognition. The specific orthography that a child is acquiring has been identified as a central element influencing reading acquisition and dyslexia. However, the development of reliable metrics to measure differences between language scripts hasn't received much attention so far. This paper therefore reviews metrics proposed in the literature for quantifying orthographic transparency, syllabic complexity, and morphological complexity of alphabetic languages...
2017: Reading and Writing
https://www.readbyqxmd.com/read/28913645/local-analgesia-in-paediatric-dentistry-a-systematic-review-of-techniques-and-pharmacologic-agents
#3
REVIEW
G Klingberg, K Ridell, S Brogårdh-Roth, M Vall, H Berlin
PURPOSE: To evaluate the evidence supporting effects and adverse effects of local analgesia using different pharmacological agents and injection techniques during dental treatment in children and adolescents aged 3-19 years. METHODS: A systematic literature search of databases including PubMed, Cochrane, and Scopus was conducted in November 2016. The PRISMA-statement was followed. Two review authors independently assessed the selected randomised control trials for risk of bias and quality...
September 14, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28905677/ethical-tensions-a-qualitative-systematic-review-of-new-graduate-perceptions
#4
Tori Hazelwood, Carolyn M Murray, Amy Baker, Mandy Stanley
BACKGROUND: New graduate transition into the workforce is challenging and can involve managing ethical tensions. Ethical tensions cause new graduates to doubt their capabilities due to their lack of experience. To support new graduates, we need to know what these ethical tensions are. OBJECTIVES: To explore the ethical tensions perceived to occur in practice for new graduate health professionals. RESEARCH DESIGN: This qualitative systematic review involved a search of five databases (Medline, EMBASE, AMED, CINAHL and Scopus) which resulted in the retrieval of 3554 papers...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28901841/re-reading-homonationalism-an-israeli-spatial-perspective
#5
Gilly Hartal, Orna Sasson-Levy
In this paper we stress the need for specifically located understandings of the concept of homonationalism, by introducing an analysis of spatial and political power relations dissecting disparate constructions of LGBT arenas. The paper explores three spaces: Tel-Aviv - an urban space of LGBT belonging, Jerusalem - the Israeli capital where being an LGBT individual is problematic both in public and in private spaces and Kiryat-Shmona - a conservative and peripheral underprivileged town in the north of Israel...
September 13, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28892407/nonparametric-bootstrap-technique-for-calibrating-surgical-smartforceps-theory-and-application
#6
Parisa Azimaee, Mohammad Jafari Jozani, Yaser Maddahi, Kourosh Zareinia, Garnette R Sutherland
Knowledge of forces, exerted on the brain tissue during the performance of neurosurgical tasks, is critical for quality assurance, case rehearsal, and training purposes. Quantifying the interaction forces has been made possible by developing SmartForceps, a bipolar forceps retrofitted by a set of strain gauges. The forces are estimated using voltages read from strain gauges. We therefore need to quantify the force-voltage relationship to estimate the interaction forces during microsurgery. This problem has been addressed in the literature by following the physical and deterministic properties of the force-sensing strain gauges without obtaining the precision associated with each estimate...
September 11, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28887532/nano-integrated-suspended-polymeric-microfluidics-spmf-platform-for-ultra-sensitive-bio-molecular-recognition-of-bovine-growth-hormones
#7
Hamid Sadabadi, Muthukumaran Packirisamy
The development of sensitive platforms for the detection of biomolecules recognition is an extremely important problem in clinical diagnostics. In microcantilever (MC) transducers, surface-stress is induced upon bimolecular interaction which is translated into MC deflection. This paper presents a cost-effective and ultra-sensitive MC-based biosensing platform. To address these goals, the need for costly high-resolution read-out system has been eliminated by reducing the cantilever compliance through developing a polymer-based cantilever...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28886503/developing-and-testing-transferability-and-feasibility-of-a-model-for-educators-using-simulation-based-learning-a-european-collaboration
#8
Rikke Buus Bøje, Andrew Bland, Andrew Sutton, Tina Hartvigsen, Leena Hannula, Jaana Maija Koivisto, Eija Raussi-Lehto, Stephen Prescott
BACKGROUND: There is a pragmatic and often inconsistent approach of embedding simulation-based learning into nursing programmes. This paper details a European collaboration that designed a model for educator facilitation for educators utilizing simulation-based education. OBJECTIVES: The objectives of the study were to develop a model to educate the educators who deliver simulation-based learning and to test to which extent this model could be transferred to education providers in different national settings...
August 25, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28873806/user-centered-reading-intervention-for-individuals-with-autism-and-intellectual-disability
#9
Anita Yakkundi, Karola Dillenburger, Lizbeth Goodman, Katerina Dounavi
Individuals with autism and intellectual disability (ID) have complex learning needs and often have difficulty in acquiring reading comprehension skills using conventional teaching tools. Evidence based reading interventions for these learners and the use of assistive technology and application of behaviour analysis to develop user-centered teaching is discussed in this paper.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28870182/reviewing-clinical-guideline-development-tools-features-and-characteristics
#10
Soudabeh Khodambashi, Øystein Nytrø
BACKGROUND: To improve consistency and streamline development and publication of clinical guidelines (GL), there is a need for appropriate software support. We have found few specific tools for the actual authoring and maintaining of GLs, and correspondingly few analyses or reviews of GL development tool functionality. In order to assist GL developers in selecting and evaluating tools, this study tries to address the perceived gap by pursuing four goals: 1) identifying available tools, 2) reviewing a representative group of tools and their supported functionalities, 3) uncovering themes of features that the studied tools support, and 4) compare the selected tools with respect to the themes...
September 4, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28811666/the-essential-kinase-atr-ensuring-faithful-duplication-of-a-challenging-genome
#11
REVIEW
Joshua C Saldivar, David Cortez, Karlene A Cimprich
One way to preserve a rare book is to lock it away from all potential sources of damage. Of course, an inaccessible book is also of little use, and the paper and ink will continue to degrade with age in any case. Like a book, the information stored in our DNA needs to be read, but it is also subject to continuous assault and therefore needs to be protected. In this Review, we examine how the replication stress response that is controlled by the kinase ataxia telangiectasia and Rad3-related (ATR) senses and resolves threats to DNA integrity so that the DNA remains available to read in all of our cells...
August 16, 2017: Nature Reviews. Molecular Cell Biology
https://www.readbyqxmd.com/read/28762098/preprocessing-prediction-of-advanced-algorithms-for-medical-imaging
#12
Bella Fadida-Specktor
Advanced medical imaging algorithms (such as bone removal, vessel segmentation, or a lung nodule detection) can provide extremely valuable information to the radiologists, but they might sometimes be very time consuming. Being able to run the algorithms in advance can be a possible solution. However, we do not know which algorithm to run on a given dataset before it is actually used. It is possible to manually insert matching rules for preprocessing algorithms, but it requires high maintenance and does not work well in practice...
July 31, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28748909/von-hippel-lindau-disease-when-neurosurgery-meets-nephrology-ophthalmology-and-genetics
#13
Francesco Signorelli, Giovanni Piscopo, Sophie Giraud, Silvana Guerriero, Antonio Laborante, Maria E Latronico, Gennaro Chimenti, Rodolfo Maduri, Domenico Chirchiglia, Angelo Lavano, Jacques Guyotat, Giovanni Alessio, Loreto Gesualdo
INTRODUCTION: Von Hippel-Lindau (VHL) disease is a dominantly inherited condition associated with tumors in multiple organs, whose treatment requires heightened multidisciplinary teamwork. Therefore, a document summarizing all the pertinent knowledge is needed to enhance coordination of care. EVIDENCE ACQUISITION: A systematic review of the literature from the Medline, Embase and Cochrane Central databases was performed. From 1970 to 2017, all articles meeting specific inclusion criteria were included by at least one specialist physician for each field...
July 26, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28741800/eteplirsen-for-the-treatment-of-duchenne-muscular-dystrophy-quality-of-evidence-concerns-an-alternative-viewpoint
#14
Adriane N Irwin, Megan C Herink
We read the paper by Reinig AM and colleagues entitled "Advances in the Treatment of Duchenne Muscular Dystrophy: New and Emerging Pharmacotherapies" with great interest.(1) The authors discuss several novel therapies to increase production of dystrophin in myocytes, of which, eteplirsen (Exondys) is the only currently approved by the US Food & Drug Administration (FDA).(2) Pharmacologic management of Duchenne muscular dystrophy (DMD) centers on the use of glucocorticoids which works by decreasing inflammation and reducing immune system activity...
July 25, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28728059/iterative-variational-mode-decomposition-based-automated-detection-of-glaucoma-using-fundus-images
#15
Shishir Maheshwari, Ram Bilas Pachori, Vivek Kanhangad, Sulatha V Bhandary, U Rajendra Acharya
Glaucoma is one of the leading causes of permanent vision loss. It is an ocular disorder caused by increased fluid pressure within the eye. The clinical methods available for the diagnosis of glaucoma require skilled supervision. They are manual, time consuming, and out of reach of common people. Hence, there is a need for an automated glaucoma diagnosis system for mass screening. In this paper, we present a novel method for an automated diagnosis of glaucoma using digital fundus images. Variational mode decomposition (VMD) method is used in an iterative manner for image decomposition...
September 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28723916/stakeholders-views-and-experiences-of-care-and-interventions-for-addressing-frailty-and-pre-frailty-a-meta-synthesis-of-qualitative-evidence
#16
Barbara D'Avanzo, Rachel Shaw, Silvia Riva, Joao Apostolo, Elzbieta Bobrowicz-Campos, Donata Kurpas, Maria Bujnowska, Carol Holland
Frailty is a common condition in older age and is a public health concern which requires integrated care and involves different stakeholders. This meta-synthesis focuses on experiences, understanding, and attitudes towards screening, care, intervention and prevention for frailty across frail and healthy older persons, caregivers, health and social care practitioners. Studies published since 2001 were identified through search of electronic databases; 81 eligible papers were identified and read in full, and 45 papers were finally included and synthesized...
2017: PloS One
https://www.readbyqxmd.com/read/28719766/energy-expenditure-of-standing-compared-to-sitting-while-conducting-office-tasks
#17
Jill Burns, Cuisle Forde, Sara Dockrell
Objectives This study aimed to investigate the energy expenditure of common office-based tasks. The objectives were to: (a) test the classification of tasks as sedentary or light-intensity physical activity and (b) compare the energy expenditure of tasks under two postural conditions (sitting and standing). Background The sedentary nature of office work has been highlighted as a health risk, and strategies to reduce sedentary behavior at work have been developed. However, there is limited evidence to guide the utilization of sit-stand workstations in the workplace for metabolic health benefits...
July 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28699568/evaluation-of-the-informatician-perspective-determining-types-of-research-papers-preferred-by-clinicians
#18
Boshu Ru, Xiaoyan Wang, Lixia Yao
BACKGROUND: To deliver evidence-based medicine, clinicians often reference resources that are useful to their respective medical practices. Owing to their busy schedules, however, clinicians typically find it challenging to locate these relevant resources out of the rapidly growing number of journals and articles currently being published. The literature-recommender system may provide a possible solution to this issue if the individual needs of clinicians can be identified and applied...
July 5, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28696841/international-multi-site-survey-on-the-use-of-online-support-groups-in-bipolar-disorder
#19
Rita Bauer, Jörn Conell, Tasha Glenn, Martin Alda, Raffaella Ardau, Bernhard T Baune, Michael Berk, Yuly Bersudsky, Amy Bilderbeck, Alberto Bocchetta, Letizia Bossini, Angela M Paredes Castro, Eric Y W Cheung, Caterina Chillotti, Sabine Choppin, Maria Del Zompo, Rodrigo Dias, Seetal Dodd, Anne Duffy, Bruno Etain, Andrea Fagiolini, Miryam Fernández Hernandez, Julie Garnham, John Geddes, Jonas Gildebro, Ana Gonzalez-Pinto, Guy M Goodwin, Paul Grof, Hirohiko Harima, Stefanie Hassel, Chantal Henry, Diego Hidalgo-Mazzei, Vaisnvy Kapur, Girish Kunigiri, Beny Lafer, Erik R Larsen, Ute Lewitzka, Rasmus W Licht, Anne Hvenegaard Lund, Blazej Misiak, Patryk Piotrowski, Scott Monteith, Rodrigo Munoz, Takako Nakanotani, René E Nielsen, Claire O'donovan, Yasushi Okamura, Yamima Osher, Andreas Reif, Philipp Ritter, Janusz K Rybakowski, Kemal Sagduyu, Brett Sawchuk, Elon Schwartz, Ângela M Scippa, Claire Slaney, Ahmad H Sulaiman, Kirsi Suominen, Aleksandra Suwalska, Peter Tam, Yoshitaka Tatebayashi, Leonardo Tondo, Eduard Vieta, Maj Vinberg, Biju Viswanath, Julia Volkert, Mark Zetin, Peter C Whybrow, Michael Bauer
BACKGROUND: Peer support is an established component of recovery from bipolar disorder, and online support groups may offer opportunities to expand the use of peer support at the patient's convenience. Prior research in bipolar disorder has reported value from online support groups. AIMS: To understand the use of online support groups by patients with bipolar disorder as part of a larger project about information seeking. METHODS: The results are based on a one-time, paper-based anonymous survey about information seeking by patients with bipolar disorder, which was translated into 12 languages...
July 11, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28673253/an-improved-filtering-algorithm-for-big-read-datasets-and-its-application-to-single-cell-assembly
#20
Axel Wedemeyer, Lasse Kliemann, Anand Srivastav, Christian Schielke, Thorsten B Reusch, Philip Rosenstiel
BACKGROUND: For single-cell or metagenomic sequencing projects, it is necessary to sequence with a very high mean coverage in order to make sure that all parts of the sample DNA get covered by the reads produced. This leads to huge datasets with lots of redundant data. A filtering of this data prior to assembly is advisable. Brown et al. (2012) presented the algorithm Diginorm for this purpose, which filters reads based on the abundance of their k-mers. METHODS: We present Bignorm, a faster and quality-conscious read filtering algorithm...
July 3, 2017: BMC Bioinformatics
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