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https://www.readbyqxmd.com/read/28634645/comparative-evaluation-of-preliminary-screening-methods-for-colorectal-cancer-in-a-mass-program
#1
Ding Ye, Qiuchi Huang, Qilong Li, Xiyi Jiang, Mayila Mamat, Mengling Tang, Jianbing Wang, Kun Chen
BACKGROUND: The fecal immunochemical test (FIT) has been widely used in preliminary screening for colorectal cancer (CRC). The high-risk factor questionnaire (HRFQ) and quantitative risk-assessment method (QRAM) are recommended for estimating the risk of CRC qualitatively and quantitatively in China. AIM: We aimed to prospectively compare the diagnostic values of CRC preliminary screening methods to identify which method is preferable as a screening strategy. METHODS: Individuals aged 40-74 years old were enrolled in a mass CRC screening program from January 1, 2007 to December 31, 2014, in Jiashan County, Zhejiang Province, China...
June 20, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28633487/high-intensity-interval-training-hiit-improves-physical-performance-and-frailty-in-aged-mice
#2
Kenneth Ladd Seldeen, Ginger Lasky, Merced Maria Leiker, Manhui Pang, Kirkwood Ely Personius, Bruce Robert Troen
Sarcopenia and frailty are highly prevalent in older individuals, increasing the risk of disability and loss of independence. High intensity interval training (HIIT) may provide a robust intervention for both sarcopenia and frailty by achieving both strength and endurance benefits with lower time commitments than other exercise regimens. To better understand the impacts of HIIT during aging, we compared 24-month-old C57BL/6J sedentary mice with those that were administered 10-minute uphill treadmill HIIT sessions three times per week over 16 weeks...
June 17, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28633001/impact-of-4-weeks-of-interval-training-on-resting-metabolic-rate-fitness-and-health-related-outcomes
#3
Matthew M Schubert, Holly E Clarke, Rebekah F Seay, Katie K Spain
PURPOSE: Resting metabolic rate (RMR) and substrate oxidation (RER) are important indicators of health. The effects of interval training on RMR have not been thoroughly investigated, which was the purpose of the present study. METHODS: Thirty men and women (mean ± SD age and VO2max: 28.8 ± 7.6 yrs and 33.0 ± 8.3 mL∙kg-1∙min-1) completed 4 weeks of Wingate-based sprint interval training (SIT), repeated 1-minute high-intensity intervals (HIIT), or served as controls (CON)...
June 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28630583/acute-modification-of-cardiac-autonomic-function-of-high-intensity-interval-training-in-collegiate-male-soccer-players-with-different-chronotype-a-cross-over-study
#4
Matteo Bonato, Luca Agnello, Letizia Galasso, Angela Montaruli, Eliana Roveda, Giampiero Merati, Antonio La Torre, Jacopo A Vitale
The purpose of this study was to evaluate if the time of the day (8.00 a.m. vs 8.00 p.m.) and chronotype could influence autonomic cardiac control in soccer players in relation to an acute session of high-intensity interval training. The morningness-eveningness questionnaire was administered to recruit Morning-type and Evening-type collegiate male soccer players. Therefore, 24 players (12 Morning-types and 12 Evening-types) were randomly assigned, to either morning (n = 12; age 23 ± 3 years; height 1.75 ± 0...
June 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28630575/acute-and-post-exercise-physiological-responses-to-high-intensity-interval-training-in-endurance-and-sprint-athletes
#5
Lukas Cipryan, Gerhard Tschakert, Peter Hofmann
The purpose of the presented study was to compare acute and post-exercise differences in cardiorespiratory, metabolic, cardiac autonomic, inflammatory and muscle damage responses to high-intensity interval exercise (HIIT) between endurance and sprint athletes. The study group consisted of sixteen highly-trained males (age 22.1 ± 2.5 years) participating in endurance (n = 8) or sprint (n = 8) sporting events. All the participants underwent three exercise sessions: short HIIT (work interval duration 30s), long HIIT (3min) and constant load exercise (CE)...
June 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28629510/screening-strategies-for-atrial-fibrillation-a-systematic-review-and-cost-effectiveness-analysis
#6
Nicky J Welton, Alexandra McAleenan, Howard Hz Thom, Philippa Davies, Will Hollingworth, Julian Pt Higgins, George Okoli, Jonathan Ac Sterne, Gene Feder, Diane Eaton, Aroon Hingorani, Christopher Fawsitt, Trudie Lobban, Peter Bryden, Alison Richards, Reecha Sofat
BACKGROUND: Atrial fibrillation (AF) is a common cardiac arrhythmia that increases the risk of thromboembolic events. Anticoagulation therapy to prevent AF-related stroke has been shown to be cost-effective. A national screening programme for AF may prevent AF-related events, but would involve a substantial investment of NHS resources. OBJECTIVES: To conduct a systematic review of the diagnostic test accuracy (DTA) of screening tests for AF, update a systematic review of comparative studies evaluating screening strategies for AF, develop an economic model to compare the cost-effectiveness of different screening strategies and review observational studies of AF screening to provide inputs to the model...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28628396/differential-in-maximal-aerobic-capacity-by-sex-in-collegiate-endurance-athletes-consuming-a-marginally-low-carbohydrate-diet
#7
Marissa N Baranauskas, Brian Miller, Jordan T Olson, Michelle Boltz, Laura Richardson, Matthew Juravich, Ronald Otterstetter
PURPOSE: Although current sports nutrition recommendations advocate for a high carbohydrate (CHO) intake among endurance athletes, recent research has suggested that training with low CHO availability may augment adaptations to aerobic training. The purpose of this study was to observe the dietary habits of collegiate distance runners and to investigate the effects of habitual CHO intake on aerobic performance [VO2max(post)] during a competitive season. METHODS: During an 8-week trial period, 12 (N = 12) collegiate track athletes recorded their self-selected dietary intake via 24-hour recall...
June 19, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28628064/exercise-training-reduces-intrathoracic-fat-regardless-of-defective-glucose-tolerance
#8
Sanna M Honkala, Kumail K Motiani, Jari-Joonas Eskelinen, Anna Savolainen, Virva Saunavaara, Kirsi A Virtanen, Eliisa Löyttyniemi, Jukka Kapanen, Juhani Knuuti, Kari K Kalliokoski, Jarna C Hannukainen
PURPOSE: Epicardial (EAT) and pericardial (PAT) fat masses and myocardial triglyceride content (MTC) are enlarged in obesity and insulin resistance. We studied whether the high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) similarly decrease ectopic fat in and around the heart and whether the decrease is similar in healthy subjects and subjects with defective glucose tolerance (DGT). METHODS: A total of 28 healthy men (body mass index = 20...
July 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28620311/physiological-adaptations-to-hypoxic-vs-normoxic-training-during-intermittent-living-high
#9
Stefan De Smet, Paul van Herpt, Gommaar D'Hulst, Ruud Van Thienen, Marc Van Leemputte, Peter Hespel
In the setting of "living high," it is unclear whether high-intensity interval training (HIIT) should be performed "low" or "high" to stimulate muscular and performance adaptations. Therefore, 10 physically active males participated in a 5-week "live high-train low or high" program (TR), whilst eight subjects were not engaged in any altitude or training intervention (CON). Five days per week (~15.5 h per day), TR was exposed to normobaric hypoxia simulating progressively increasing altitude of ~2,000-3,250 m...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28620291/network-wide-adaptive-burst-detection-depicts-neuronal-activity-with-improved-accuracy
#10
Inkeri A Välkki, Kerstin Lenk, Jarno E Mikkonen, Fikret E Kapucu, Jari A K Hyttinen
Neuronal networks are often characterized by their spiking and bursting statistics. Previously, we introduced an adaptive burst analysis method which enhances the analysis power for neuronal networks with highly varying firing dynamics. The adaptation is based on single channels analyzing each element of a network separately. Such kind of analysis was adequate for the assessment of local behavior, where the analysis focuses on the neuronal activity in the vicinity of a single electrode. However, the assessment of the whole network may be hampered, if parts of the network are analyzed using different rules...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28615010/internet-based-perioperative-exercise-program-in-patients-with-barrett-s-carcinoma-scheduled-for-esophagectomy-ipep-study-a-prospective-randomized-controlled-trial
#11
Daniel Pfirrmann, Suzan Tug, Oana Brosteanu, Matthias Mehdorn, Martin Busse, Peter P Grimminger, Florian Lordick, Torben Glatz, Jens Hoeppner, Hauke Lang, Perikles Simon, Ines Gockel
BACKGROUND: Patients undergoing surgery for esophageal cancer have a high risk for postoperative deterioration of lung function and pulmonary complications. This is partly due to one-lung ventilation during thoracotomy. This often accounts for prolonged stay on intensive care units, delayed postoperative reconvalescence and reduced quality of life. Socioeconomic disadvantages can result from these problems. Physical preconditioning has become a crucial leverage to optimize fitness and lung function in patients scheduled for esophagectomy, in particular during the time period of neoadjuvant therapy...
June 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28613384/communication-skills-training-for-mental-health-professionals-working-with-people-with-severe-mental-illness
#12
REVIEW
Alexia Papageorgiou, Yoon K Loke, Michelle Fromage
BACKGROUND: Research evidence suggests that both mental health professionals and people with severe mental health illness such as schizophrenia or schizoaffective disorder find it difficult to communicate with each other effectively about symptoms, treatments and their side effects so that they reach a shared understanding about diagnosis, prognosis and treatment. Effective use of communication skills in mental health interactions could be associated with increased patient satisfaction and adherence to treatment...
June 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28612219/prospective-phase-ii-study-evaluating-the-efficacy-of-swallow-ability-screening-tests-and-pneumonia-prevention-using-a-team-approach-for-elderly-patients-with-gastric-cancer
#13
Yuichiro Miki, Rie Makuuchi, Shinsaku Honda, Masanori Tokunaga, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Takashi Yurikusa, Akira Tanuma, Masanori Terashima
BACKGROUND: Aging partly impairs swallowing function, which is considered a risk factor for postoperative pneumonia (PP). We evaluated the efficacy of a new team-based strategy to reduce the incidence of PP in elderly patients with gastric cancer. METHODS: This single-center, prospective phase II study included elderly patients (≥75 years old) with gastric cancer undergoing gastric surgery. The primary endpoint was the incidence of Clavien-Dindo grade II or higher PP...
June 13, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28611681/dose-response-of-high-intensity-training-hit-on-atheroprotective-mirna-126-levels
#14
Boris Schmitz, Katrin Schelleckes, Johanna Nedele, Lothar Thorwesten, Andreas Klose, Malte Lenders, Michael Krüger, Eva Brand, Stefan-Martin Brand
Aim: MicroRNA-126 (miR-126) exerts beneficial effects on vascular integrity, angiogenesis, and atherosclerotic plaque stability. The purpose of this investigation was to analyze the dose-response relationship of high-intensity interval training (HIIT) on miR-126-3p and -5p levels. Methods: Sixty-one moderately trained individuals (females = 31 [50.8%]; 22.0 ± 1.84 years) were consecutively recruited and allocated into three matched groups using exercise capacity. During a 4-week intervention a HIIT group performed three exercise sessions/week of 4 × 30 s at maximum speed (all-out), a progressive HIIT (proHIIT) group performed three exercise sessions/week of 4 × 30 s at maximum speed (all-out) with one extra session every week (up to 7 × 30 s) and a low-intensity training (LIT) control group performed three exercise sessions/week for 25 min <75% of maximum heart rate...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28605609/effects-of-macro-and-micro-nutrients-on-exercise-induced-hepcidin-response-in-highly-trained-endurance-athletes
#15
Dylan Timothy Dahlquist, Trent Stellingwerff, Brad Pendleton Dieter, Donald C McKenzie, Michael S Koehle
Iron deficiency (ID) has ergolytic effects on athletic performance. Exercise induced inflammation impedes iron absorption in the digestive tract by up-regulating the expression of the iron regulatory protein, hepcidin. Limited research indicates the potential of specific macro- and micro- nutrients on blunting exercise induced hepcidin. Therefore, we investigated the effects of post-exercise supplementation with protein and carbohydrate (CHO) and vitamins D3 and K2 on the post-exercise hepcidin response. Ten highly-trained male cyclists (age: 26...
June 12, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28604322/training-and-support-to-improve-icd-coding-quality-a-controlled-before-and-after-impact-evaluation
#16
Robin Dyers, Grant Ward, Shane Du Plooy, Stephanus Fourie, Juliet Evans, Hassan Mahomed
BACKGROUND: The proposed National Health Insurance policy for South Africa (SA) requires hospitals to maintain high-quality International Statistical Classification of Diseases (ICD) codes for patient records. While considerable strides had been made to improve ICD coding coverage by digitising the discharge process in the Western Cape Province, further intervention was required to improve data quality. The aim of this controlled before-and-after study was to evaluate the impact of a clinician training and support initiative to improve ICD coding quality...
May 24, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28602046/exercise-interventions-for-cerebral-palsy
#17
REVIEW
Jennifer M Ryan, Elizabeth E Cassidy, Stephen G Noorduyn, Neil E O'Connell
BACKGROUND: Cerebral palsy (CP) is a neurodevelopmental disorder resulting from an injury to the developing brain. It is the most common form of childhood disability with prevalence rates of between 1.5 and 3.8 per 1000 births reported worldwide. The primary impairments associated with CP include reduced muscle strength and reduced cardiorespiratory fitness, resulting in difficulties performing activities such as dressing, walking and negotiating stairs.Exercise is defined as a planned, structured and repetitive activity that aims to improve fitness, and it is a commonly used intervention for people with CP...
June 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28599623/-reliability-of-the-norwegian-version-of-the-short-physical-performance-battery-in-older-people-with-and-without-dementia
#18
Cecilie Fromholt Olsen, Astrid Bergland
BACKGROUND: The purpose of the study was to establish the test-retest reliability of the Norwegian version of the Short Physical Performance Battery (SPPB). METHODS: This was a cross- sectional reliability study. A convenience sample of 61 older adults with a mean age of 88.4(8.1) was tested by two different physiotherapists at two time points. The mean time interval between tests was 2.5 days. The Intraclass Correlation Coefficient model 3.1 (ICC, 3.1) with 95% confidence intervals as well as the weighted Kappa (K) were used as measures of relative reliability...
June 9, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28598948/causes-for-pauses-during-simulated-pediatric-cardiac-arrest
#19
David Oren Kessler, Dawn Taylor Peterson, Alexis Bragg, Yiqun Lin, John Zhong, Jonathan Duff, Mark Adler, Linda Brown, Farhan Bhanji, Jennifer Davidson, David Grant, Adam Cheng
OBJECTIVES: Pauses in cardiopulmonary resuscitation negatively impact clinical outcomes; however, little is known about the contributing factors. The objective of this study is to determine the frequency, duration, and causes for pauses during cardiac arrest. DESIGN: This is a secondary analysis of video data collected from a prospective multicenter trial. Twenty-six simulated pediatric cardiac arrest scenarios each lasting 12 minutes in duration were analyzed by two independent reviewers to document events surrounding each pause in chest compressions...
June 8, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28597102/effects-of-progressive-resistance-training-and-weight-loss-versus-weight-loss-alone-on-inflammatory-and-endothelial-biomarkers-in-older-adults-with-type-2-diabetes
#20
Eliza G Miller, Parneet Sethi, Caryl A Nowson, David W Dunstan, Robin M Daly
PURPOSE: Type 2 diabetes has been associated with an increase in inflammatory and endothelial biomarkers, which are associated with an increased risk of cardiovascular disease and diabetes-related complications. This study examined the effects of high-intensity progressive resistance training (PRT) with moderate weight loss (WL) versus WL alone on inflammatory and endothelial biomarkers in older overweight adults with type 2 diabetes. METHODS: This was a 12-month randomized controlled trial in which 36 inactive, overweight adults aged 60-80 years with poorly controlled type 2 diabetes were randomized to 6 months of supervised PRT + WL or stretching (sham) exercise plus WL followed by 6 months of home-training without dietary modification...
June 8, 2017: European Journal of Applied Physiology
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