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High interval training

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https://www.readbyqxmd.com/read/29778857/development-of-a-risk-score-based-on-aortic-calcification-to-predict-1-year-mortality-after-transcatheter-aortic-valve-replacement
#1
Pierre Lantelme, Hélène Eltchaninoff, Muriel Rabilloud, Géraud Souteyrand, Marion Dupré, Marco Spaziano, Marc Bonnet, Clément Becle, Benjamin Riche, Eric Durand, Erik Bouvier, Jean-Nicolas Dacher, Pierre-Yves Courand, Lucie Cassagnes, Eduardo E Dávila Serrano, Pascal Motreff, Loic Boussel, Thierry Lefèvre, Brahim Harbaoui
OBJECTIVES: The aim of this study was to develop a new scoring system based on thoracic aortic calcification (TAC) to predict 1-year cardiovascular and all-cause mortality. BACKGROUND: A calcified aorta is often associated with poor prognosis after transcatheter aortic valve replacement (TAVR). A risk score encompassing aortic calcification may be valuable in identifying poor TAVR responders. METHODS: The C4 CAPRI (4 Cities for Assessing CAlcification PRognostic Impact) multicenter study included a training cohort (1,425 patients treated using TAVR between 2010 and 2014) and a contemporary test cohort (311 patients treated in 2015)...
May 11, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29775986/effects-of-two-training-programs-on-transcriptional-levels-of-neurotrophins-and-glial-cells-population-in-hippocampus-of-experimental-multiple-sclerosis
#2
Maryam Naghibzadeh, Rouhollah Ranjbar, Mohammad Reza Tabandeh, Abdolhamid Habibi
The aim of the present study was to investigate the effects of high-intensity interval training (HIIT) versus low-intensity continuous training (LICT) on transcriptional levels of neurotrophic factors and oligodendrocyte/microglia cell loss in a cuprizone (CP) induced animal model of demyelination. Male C57BL/6 mice were assigned to six groups: control (C), cuprizone-induced demyelination (CP), interval training (IT), continuous training (CT), IT plus CP (ITCP), and CT plus CP (CTCP). Training programs on the treadmill were performed for four weeks, and then demyelination was induced by feeding mice a diet containing 0...
May 18, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29773695/automated-computer-guided-pasi-measurements-by-digital-image-analysis-versus-conventional-physicians-pasi-calculations-study-protocol-for-a-comparative-single-centre-observational-study
#3
Christine Fink, Lorenz Uhlmann, Christina Klose, Holger A Haenssle
INTRODUCTION: Reliable and accurate assessment of severity in psoriasis is very important in order to meet indication criteria for initiation of systemic treatment or to evaluate treatment efficacy. The most acknowledged tool for measuring the extent of psoriatic skin changes is the Psoriasis Area and Severity Index (PASI). However, the calculation of PASI can be tedious and subjective and high intraobserver and interobserver variability is an important concern. Therefore, there is a great need for a standardised and objective method that guarantees a reproducible PASI calculation...
May 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29771855/does-multimodal-rehabilitation-for-ankle-instability-improve-patients-self-assessed-functional-outcomes-a-network-meta-analysis
#4
Konstantinos Tsikopoulos, Dimitris Mavridis, Dimitrios Georgiannos, Haris S Vasiliadis
BACKGROUND: Although there are many nonsurgical treatment options for the primary management of chronic ankle instability, the most effective nonoperative intervention has not been defined. QUESTIONS/PURPOSES: The purpose of this study was to perform a network meta-analysis to compare the results of different standalone and/or combined nonsurgical interventions on chronic ankle instability as measured by (1) the Cumberland Ankle Instability Tool (CAIT) at 0 to 6 months after treatment and (2) treatment-related complications...
June 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29771824/psychological-and-behavioral-responses-to-interval-and-continuous-exercise
#5
Matthew J Stork, Martin J Gibala, Kathleen A Martin Ginis
PURPOSE: To compare psychological responses to, and preferences for, moderate-intensity continuous training (MICT), high-intensity interval training (HIIT), and sprint interval training (SIT) among inactive adults; and to investigate the relationships between affect, enjoyment, exercise preferences, and subsequent exercise behavior over a 4-wk follow-up period. METHODS: Thirty inactive men and women (21.23±3.81 y), inexperienced with HIIT or SIT, completed three trials of cycle ergometer exercise in random order on separate days: MICT (45min continuous; ~70-75% of heart rate maximum (HRmax)); HIIT (10x1 min bouts at ~85-90%HRmax with 1-min recovery periods); and SIT (3x20-s "all-out" sprints with 2-min recovery periods)...
May 16, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29769827/effects-of-a-4-week-very-low-carbohydrate-diet-on-high-intensity-interval-training-responses
#6
Lukas Cipryan, Daniel J Plews, Alessandro Ferretti, Phil B Maffetone, Paul B Laursen
The purpose of the study was to examine the effects of altering from habitual mixed Western-based (HD) to a very low-carbohydrate high-fat (VLCHF) diet over a 4-week timecourse on performance and physiological responses during high-intensity interval training (HIIT). Eighteen moderately trained males (age 23.8 ± 2.1 years) consuming their HD (48 ± 13% carbohydrate, 17 ± 3% protein, 35 ± 9% fat) were assigned to 2 groups. One group was asked to remain on their HD, while the other was asked to switch to a non-standardized VLCHF diet (8 ± 3% carbohydrate, 29 ± 15% protein, 63 ± 13% fat) for 4 weeks...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29769816/the-effect-of-two-different-concurrent-training-programs-on-strength-and-power-gains-in-highly-trained-individuals
#7
Henrik Petré, Pontus Löfving, Niklas Psilander
The effects of concurrent strength and endurance training have been well studied in untrained and moderately-trained individuals. However, studies examining these effects in individuals with a long history of resistance training (RT) are lacking. Additionally, few studies have examined how strength and power are affected when different types of endurance training are added to an RT protocol. The purpose of the present study was to compare the effects of concurrent training incorporating either low-volume, high-intensity interval training (HIIT, 8-24 Tabata intervals at ~150% of VO2max ) or high-volume, medium-intensity continuous endurance training (CT, 40-80 min at 70% of VO2max ), on the strength and power of highly-trained individuals...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29769247/dementia-and-physical-activity-dapa-trial-of-moderate-to-high-intensity-exercise-training-for-people-with-dementia-randomised-controlled-trial
#8
Sarah E Lamb, Bart Sheehan, Nicky Atherton, Vivien Nichols, Helen Collins, Dipesh Mistry, Sukhdeep Dosanjh, Anne Marie Slowther, Iftekhar Khan, Stavros Petrou, Ranjit Lall
OBJECTIVE: To estimate the effect of a moderate to high intensity aerobic and strength exercise training programme on cognitive impairment and other outcomes in people with mild to moderate dementia. DESIGN: Multicentre, pragmatic, investigator masked, randomised controlled trial. SETTING: National Health Service primary care, community and memory services, dementia research registers, and voluntary sector providers in 15 English regions. PARTICIPANTS: 494 people with dementia: 329 were assigned to an aerobic and strength exercise programme and 165 were assigned to usual care...
May 16, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29768508/i-scan-optical-enhancement-for-the-in-vivo-prediction-of-diminutive-colorectal-polyp-histology-results-from-a-prospective-three-phased-multicentre-trial
#9
Entcho Klenske, Steffen Zopf, Clemens Neufert, Andreas Nägel, Jürgen Siebler, Jürgen Gschossmann, Steffen Mühldorfer, Lukas Pfeifer, Sarah Fischer, Francesco Vitali, Marietta Iacucci, Subrata Ghosh, Michelle G Rath, Peter Klare, Gian E Tontini, Markus F Neurath, Timo Rath
BACKGROUND AND AIMS: Dye-less chromoendoscopy is an emerging technology for colorectal polyp characterization. Herein, we investigated whether the newly introduced I-scan optical enhancement (OE) can accurately predict polyp histology in vivo in real-time. METHODS: In this prospective three-phased study, 84 patients with 230 diminutive colorectal polyps were included. During the first two study phases, five endoscopists assessed whether analysis of polyp colour, surface and vascular pattern under i-scan OE can differentiate in vivo between adenomatous and hyperplastic polyps...
2018: PloS One
https://www.readbyqxmd.com/read/29768095/test-retest-reliability-of-kinetic-variables-measured-on-campus-board-in-sport-climbers
#10
Edgardo Alvares de Campos Abreu, Sílvia Ribeiro Santos Araújo, Gustavo Henrique da Cunha Peixoto Cançado, André Gustavo Pereira de Andrade, Mauro Heleno Chagas, Hans-Joachim Karl Menzel
Sport climbers frequently use campus board (CB) to improve their upper limb strength under similar conditions of high-difficulty sport climbing routes. The objective of this study was to assess the test-retest reliability of peak force and impulse measured using a CB instrumented with two load cells on starting holds. The same evaluator examined 22 climbers on two days with 48 h between the assessments. The participants performed five concentric lunges (CL) and five lunges with stretch-shortening cycle with 1 min intervals between repetitions and 10 min between exercises...
May 16, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29767544/the-aerobic-resistance-inspiratory-muscle-training-hypothesis-in-heart-failure
#11
Ioannis D Laoutaris
Evidence from large multicentre exercise intervention trials in heart failure patients, investigating both moderate continuous aerobic training and high intensity interval training, indicates that the 'crème de la crème' exercise programme for this population remains to be found. The 'aerobic/resistance/inspiratory (ARIS) muscle training hypothesis in heart failure' is introduced, suggesting that combined ARIS muscle training may result in maximal exercise pathophysiological and functional benefits in heart failure patients...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29765980/aerobic-interval-training-regulated-sirt3-attenuates-high-fat-diet-associated-cognitive-dysfunction
#12
Zhaoling Shi, Chen Li, Yue Yin, Zheng Yang, Han Xue, Nan Mu, Yishi Wang, Manling Liu, Heng Ma
Cognitive dysfunction is an important complicated disease in obesity. Exercise ameliorates obesity and the related cognitive dysfunction. However, the underlying mechanism is still unclear. In this study, we investigated whether aerobic interval training (AIT) could attenuate high-fat-diet- (HFD-) associated cognitive dysfunction and the possible mechanism of SIRT3-MnSOD pathway. C57BL/6 wild-type (WT) mice and SIRT3 knockout (KO) mice were randomized into control (Con) or HFD group with or without AIT training for 6 weeks...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29764892/intense-exercise-for-survival-among-men-with-metastatic-castrate-resistant-prostate-cancer-interval-gap4-a-multicentre-randomised-controlled-phase-iii-study-protocol
#13
Robert U Newton, Stacey A Kenfield, Nicolas H Hart, June M Chan, Kerry S Courneya, James Catto, Stephen P Finn, Rosemary Greenwood, Daniel C Hughes, Lorelei Mucci, Stephen R Plymate, Stephan F E Praet, Emer M Guinan, Erin L Van Blarigan, Orla Casey, Mark Buzza, Sam Gledhill, Li Zhang, Daniel A Galvão, Charles J Ryan, Fred Saad
INTRODUCTION: Preliminary evidence supports the beneficial role of physical activity on prostate cancer outcomes. This phase III randomised controlled trial (RCT) is designed to determine if supervised high-intensity aerobic and resistance exercise increases overall survival (OS) in patients with metastatic castrate-resistant prostate cancer (mCRPC). METHODS AND ANALYSIS: Participants (n=866) must have histologically documented metastatic prostate cancer with evidence of progressive disease on androgen deprivation therapy (defined as mCRPC)...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29764731/how-much-is-enough-in-rehabilitation-high-running-workloads-following-lower-limb-muscle-injury-delay-return-to-play-but-protect-against-subsequent-injury
#14
Jordan Stares, Brian Dawson, Peter Peeling, Michael Drew, Jarryd Heasman, Brent Rogalski, Marcus Colby
OBJECTIVES: Examine the influence of rehabilitation training loads on return to play (RTP) time and subsequent injury in elite Australian footballers. DESIGN: Prospective cohort study. METHODS: Internal (sessional rating of perceived exertion: sRPE) and external (distance, sprint distance) workload and lower limb non-contact muscle injury data was collected from 58 players over 5 seasons. Rehabilitation periods were analysed for running workloads and time spent in 3 rehabilitation stages (1: off-legs training, 2: non-football running, 3: group football training) was calculated...
April 10, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29762252/high-intensity-interval-or-continuous-moderate-exercise-a-24-week-pilot-trial
#15
Sean R Locke, Jessica E Bourne, Mark R Beauchamp, Jonathan P Little, Julianne Barry, Joel Singer, Mary E Jung
PURPOSE: High-intensity interval training (HIIT) may lead to superior cardiometabolic improvements when compared to moderate-intensity continuous training (MICT). However, adherence to HIIT requires examination. The purpose of this pilot study was to examine moderate-to-vigorous physical activity (MVPA) adherence 24 weeks following a brief counselling intervention combined with either HIIT or MICT. METHODS: Individuals at high risk of type 2 diabetes (T2D) were randomized to HIIT (n = 15) or MICT (n = 17) and completed 10 exercise sessions accompanied by a brief 10-minute counselling intervention over a 2-week period...
May 14, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29762196/high-intensity-interval-training-and-continuous-aerobic-exercise-interventions-to-promote-self-initiated-quit-attempts-in-young-adults-who-smoke-feasibility-acceptability-and-lessons-learned-from-a-randomized-pilot-trial
#16
Alicia Allen, Samantha C Carlson, Tyler A Bosch, Lynn E Eberly, Kola Okuyemi, Uma Nair, Judith S Gordon
OBJECTIVES: While exercise significantly reduces craving for cigarettes, the effect of exercise on self-initiation of quit attempts is less known. Therefore, this randomized pilot study explored the effect of starting an exercise program on self-initiated quit attempts, and also the feasibility and acceptability of a novel exercise intervention, high-intensity interval training (HIIT), as compared with a more traditional continuous aerobic (CA) exercise intervention. METHODS: Participants smoked (≥5 cigarettes/d), were aged 18 to 40 years, and wanted to increase their exercise...
May 14, 2018: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29761054/is-high-intensity-interval-cycling-feasible-and-more-beneficial-than-continuous-cycling-for-knee-osteoarthritic-patients-results-of-a-randomised-control-feasibility-trial
#17
Justin W Keogh, Josephine Grigg, Christopher J Vertullo
Background: Knee osteoarthritis (OA) patients often suffer joint pain and stiffness, which contributes to negative changes in body composition, strength, physical performance (function), physical activity and health-related quality of life. To reduce these symptoms and side effects of knee OA, moderate-intensity continuous training (MICT) cycling is often recommended. While resistance training is considered the optimal form of training to improve sarcopenic outcomes, it imposes higher joint loads and requires supervision, either initially or continuously by trained exercise professionals...
2018: PeerJ
https://www.readbyqxmd.com/read/29760840/clinical-ultrasound-is-safe-and-highly-specific-for-acute-appendicitis-in-moderate-to-high-pre-test-probability-patients
#18
Daniel Corson-Knowles, Frances M Russell
Introduction: Clinical ultrasound (CUS) is highly specific for the diagnosis of acute appendicitis but is operator-dependent. The goal of this study was to determine if a heterogeneous group of emergency physicians (EP) could diagnose acute appendicitis on CUS in patients with a moderate to high pre-test probability. Methods: This was a prospective, observational study of a convenience sample of adult and pediatric patients with suspected appendicitis. Sonographers received a structured, 20-minute CUS training on appendicitis prior to patient enrollment...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29754673/prevalent-digoxin-use-and-subsequent-risk-of-death-or-hospitalization-in-ambulatory-heart-failure-patients-with-a-reduced-ejection-fraction-findings-from-the-heart-failure-a-controlled-trial-investigating-outcomes-of-exercise-training-hf-action-randomized-controlled
#19
Andrew P Ambrosy, Ankeet S Bhatt, Amanda L Stebbins, Lisa M Wruck, Marat Fudim, Stephen J Greene, William E Kraus, Christopher M O'Connor, Ileana L Piña, David J Whellan, Robert J Mentz
BACKGROUND: Despite more than 200 years of clinical experience and a pivotal trial, recently published research has called into question the safety and efficacy of digoxin therapy in heart failure (HF). METHODS: HF-ACTION (ClinicalTrials.gov Number: NCT00047437) enrolled 2331 outpatients with HF and an EF ≤35% between April 2003 and February 2007 and randomized them to aerobic exercise training versus usual care. Patients were grouped according to prevalent digoxin status at baseline...
May 2018: American Heart Journal
https://www.readbyqxmd.com/read/29750700/assessment-of-a-chemotherapy-response-score-crs-system-for-tubo-ovarian-high-grade-serous-carcinoma-hgsc
#20
Helena M Ditzel, Kyle C Strickland, Emily E Meserve, Elizabeth Stover, Panagiotis A Konstantinopoulos, Ursula A Matulonis, Michael G Muto, Joyce F Liu, Colleen Feltmate, Neil Horowitz, Ross S Berkowitz, Mamta Gupta, Jonathan L Hecht, Douglas I Lin, Kirsten M Jochumsen, William R Welch, Michelle S Hirsch, Bradley J Quade, Kenneth R Lee, Christopher P Crum, George L Mutter, Marisa R Nucci, Brooke E Howitt
A chemotherapy response score (CRS) system was recently described to assess the histopathologic response and prognosis of patients with tubo-ovarian high-grade serous carcinoma (HGSC) receiving neoadjuvant chemotherapy. The current study was performed as an independent assessment of this CRS system. We retrospectively identified advanced stage HGSC patients who received neoadjuvant chemotherapy and underwent interval debulking. If available, a hemotoxylin and eosin slide from the omentum and the adnexa was selected for the study...
May 10, 2018: International Journal of Gynecological Pathology
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