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https://www.readbyqxmd.com/read/28737109/clinical-outcome-prediction-after-thrombectomy-of-proximal-middle-cerebral-artery-occlusions-by-the-appearance-of-lenticulostriate-arteries-on-magnetic-resonance-angiography-a-retrospective-analysis
#1
Johannes Kaesmacher, Kornelia Kreiser, Nathan W Manning, Alexandra S Gersing, Silke Wunderlich, Claus Zimmer, Justus F Kleine, Benedikt Wiestler, Tobias Boeckh-Behrens
Post-ischemic vasodynamic changes in infarcted brain parenchyma are common and range from hypo- to hyperperfusion. In the present study, appearance of the lenticulostriate arteries (LSAs) on postinterventional 3T time-of-flight (TOF)-MRA suggestive for altered post-stroke vasodynamics following thrombectomy was investigated. Patients who underwent thrombectomy for a proximal MCA occlusion and for whom postinterventional 3T TOF-MRA (median at day 3) was available, were included in this retrospective analysis (n=98)...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28704454/indocyanine-green-kinetics-with-near-infrared-spectroscopy-predicts-cerebral-hyperperfusion-syndrome-after-carotid-artery-stenting
#2
Ichiro Nakagawa, Hun Soo Park, Shohei Yokoyama, Shuichi Yamada, Yasushi Motoyama, Young Su Park, Takeshi Wada, Kimihiko Kichikawa, Hiroyuki Nakase
BACKGROUND: Cerebral hyperperfusion syndrome (HPS) is a potentially life-threatening complication following carotid artery stenting (CAS) and carotid endoarterectomy (CEA). Early prediction and treatment of patients at risk for HPS are required in patients undergoing CAS because HPS occurs significantly earlier after CAS than CEA. Near-infrared spectroscopy (NIRS) is often used for monitoring, and indocyanine green (ICG) kinetics by NIRS (ICG-NIRS) can detect reductions in cerebral perfusion in patients with acute stroke...
2017: PloS One
https://www.readbyqxmd.com/read/28701298/carotid-stenting-for-unilateral-stenosis-can-increase-contralateral-hemispheric-cerebral-blood-flow
#3
Akiyo Sadato, Shingo Maeda, Motoharu Hayakawa, Kazuhide Adachi, Hiroshi Toyama, Ichiro Nakahara, Yuichi Hirose
BACKGROUND: The revascularization of carotid stenosis can increase ipsilateral cerebral blood flow (CBF). Occasionally, elevated CBF is also evident on the contralateral side, but this phenomenon is poorly understood. OBJECTIVE: To analyze retrospectively the relationship between a contralateral CBF increase and several clinical and radiologic features. MATERIALS AND METHODS: We retrospectively analyzed 40 patients with unilateral cervical carotid stenosis treated by carotid artery stenting (CAS)...
July 12, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28689257/fluid-attenuated-inversion-recovery-vascular-hyperintensities-in-predicting-cerebral-hyperperfusion-after-intracranial-arterial-stenting
#4
Chih-Cheng Wan, David Yen-Ting Chen, Ying-Chi Tseng, Feng-Xian Yan, Kun-Yu Lee, Chen-Hua Chiang, Chi-Jen Chen
PURPOSE: No reliable imaging sign predicting cerebral hyperperfusion after intracranial arterial stenting (IAS) had been described in the literature. This study evaluated the effect of fluid-attenuated inversion recovery vascular hyperintensities (FVHs), also called hyperintense vessel sign on T2-weighted fluid-attenuated inversion recovery (T2-FLAIR) MR images, in predicting significant increase in cerebral blood flow (CBF) defined by arterial spin labeling (ASL) after IAS. METHODS: We reviewed ASL CBF images and T2-FLAIR MR images before (D0), 1 day after (D1), and 3 days after (D3) IAS of 16 patients...
July 8, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28687500/analysis-of-hemodynamic-changes-in-early-stage-after-carotid-stenting-by-transcranial-doppler-a-preliminary-study
#5
Ziguang Yan, Min Yang, Guochen Niu, Yinghua Zou
BACKGROUND: Cerebral hyperperfusion syndrome (CHS) or hemodynamic instability(HI), caused by the hemodynamic changes, often occur within 6 hours after carotid artery stenting (CAS) The post-procedure cerebral hemodynamic change in the early phase, less than 6 hours after CAS, is largely unknown. In this study we evaluated the cerebral hemodynamic changes in patients after CAS using transcranial Doppler (TCD). METHODS: From January, 2013 to July, 2014, medical records of 61 patients underwent CAS were reviewed retrospectively...
July 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28679968/clinical-characteristics-and-outcome-in-elderly-patients-with-traumatic-brain-injury-for-establishment-of-management-strategy
#6
Hiroshi Karibe, Toshiaki Hayashi, Ayumi Narisawa, Motonobu Kameyama, Atsuhiro Nakagawa, Teiji Tominaga
In recent years, instances of neurotrauma in the elderly have been increasing. This article addresses the clinical characteristics, management strategy, and outcome in elderly patients with traumatic brain injury (TBI). Falls to the ground either from standing or from heights are the most common causes of TBI in the elderly, since both motor and physiological functions are degraded in the elderly. Subdural, contusional and intracerebral hematomas are more common in the elderly than the young as the acute traumatic intracranial lesion...
July 5, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28666454/fluorescence-optical-imaging-and-musculoskeletal-ultrasonography-in-juvenile-idiopathic-polyarticular-disease-before-and-during-antirheumatic-treatment%C3%A2-a-multicenter-non-interventional-diagnostic-evaluation
#7
Ariane Klein, Georg Werner Just, Stephanie Gabriele Werner, Prasad T Oommen, Kirsten Minden, Ingrid Becker, Hans-Eckhard Langer, Dirk Klee, Gerd Horneff
BACKGROUND: Valid detection of inflamed joints is essential for correct classification, therapeutic decisions, prognosis and assessment of treatment efficacy in juvenile idiopathic arthritis (JIA). Fluorescence optical imaging (FOI) enables visualization of inflammation in arthritis of finger and hand joints and might be used for monitoring. METHODS: A 24-week observational study in polyarticular JIA patients newly starting treatment with methotrexate or an approved biologic was performed in three centers...
June 30, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28665168/cerebral-hyperperfusion-on-arterial-spin-labeling-mri-after-reperfusion-therapy-is-related-to-hemorrhagic-transformation
#8
Shuhei Okazaki, Hiroshi Yamagami, Takeshi Yoshimoto, Yoshiaki Morita, Haruko Yamamoto, Kazunori Toyoda, Masafumi Ihara
Early detection of hemorrhagic transformation after reperfusion therapy is crucial in acute stroke treatment. Here, we evaluated the relationship between hemorrhagic transformation and post-reperfusion hyperperfusion using pulsed arterial spin labeling (ASL) perfusion MRI and (123)I-iodoamphetamine single-photon emission-computed tomography. Patients who developed hemorrhagic transformation showed significantly higher cerebral blood flow in the affected lesion after thrombolysis and/or endovascular intervention...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28664022/intracerebral-hemorrhage-caused-by-cerebral-hyperperfusion-after-superficial-temporal-artery-to-middle-cerebral-artery-bypass-for-atherosclerotic-occlusive-cerebrovascular-disease
#9
Fumihiro Matano, Yasuo Murai, Takayuki Mizunari, Koji Adachi, Shiro Kobayashi, Akio Morita
Few papers have reported detailed accounts of intracerebral hemorrhage caused by cerebral hyperperfusion after superficial temporal artery to middle cerebral artery bypass (STA-MCA) bypass for atherosclerotic occlusive cerebrovascular disease. We report a case of vasogenic edema and subsequent intracerebral hemorrhage caused by the cerebral hyperperfusion syndrome (CHS) after STA-MCA bypass for atherosclerotic occlusive cerebrovascular disease disease without intense postoperative blood pressure control. A 63-year-old man with repeating left hemiparesis underwent magnetic resonance angiography (MRA), which revealed right internal carotid artery (ICA) occlusion...
January 2017: NMC Case Rep J
https://www.readbyqxmd.com/read/28651622/modulation-of-hepatic-perfusion-did-not-improve-recovery-from-hepatic-outflow-obstruction
#10
J Arlt, W Wei, C Xie, A Homeyer, U Settmacher, U Dahmen, O Dirsch
BACKGROUND: Focal hepatic venous outflow obstruction frequently occurs after extended liver resection and leads to a portal hypertension, arterial hypoperfusion and parenchymal necrosis. In this study, we investigated the pharmacological modulation of liver perfusion and hepatic damage in a surgical model of hepatic outflow obstruction after extended liver resection by administration of 5 different drugs in comparison to an operative intervention, splenectomy. METHODS: Male inbred Lewis rats (Lew/Crl) were subjected to right median hepatic vein ligation + 70% partial hepatectomy...
June 26, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28644110/detailed-magnetic-resonance-imaging-features-of-a-case-series-of-primary-gliosarcoma
#11
Luísa Sampaio, Paulo Linhares, José Fonseca
Objective We aimed to characterise the magnetic resonance imaging (MRI) features of a case series of primary gliosarcoma, with the inclusion of diffusion-weighted imaging and perfusion imaging with dynamic susceptibility contrast MRI. Materials and methods We conducted a retrospective study of cases of primary gliosarcoma from the Pathology Department database from January 2006 to December 2014. Clinical and demographic data were obtained. Two neuroradiologists, blinded to diagnosis, assessed tumour location, signal intensity in T1 and T2-weighted images, pattern of enhancement, diffusion-weighted imaging and dynamic susceptibility contrast MRI studies on preoperative MRI...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28643877/cerebral-haemodynamic-response-to-somatosensory-stimulation-in-neonatal-lambs
#12
Shinji Nakamura, David W Walker, Flora Y Wong
The neurovascular coupling response has been defined for the adult brain but in the neonate non-invasive measurement of local cerebral perfusion using NIRS or BOLD fMRI have yielded variable and inconsistent results, including negative responses suggesting decreased perfusion and localised tissue tissue hypoxia. Also, the impact of permissive hypercapnia (Pa CO2  > 50 mmHg) in the management of neonates on cerebrovascular responses to somatosensory input is unknown. Using NIRS to measure changes in cerebral oxy- and deoxy-haemoglobin (ΔoxyHb, ΔdeoxyHb) in 8 anaesthetised newborn lambs, we studied the cerebral haemodynamic functional response to left median nerve stimulation using stimulus trains of 1...
June 23, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28627790/regional-cerebral-blood-flow-in-opiate-dependence-relates-to-substance-use-and-neuropsychological-performance
#13
Donna E Murray, Timothy C Durazzo, Thomas P Schmidt, Troy A Murray, Christoph Abé, Joseph Guydish, Dieter J Meyerhoff
Neuroimaging of opiate-dependent individuals indicates both altered brain structure and function. Magnetic resonance-based arterial spin labeling has been used to measure noninvasively cerebral blood flow (i.e. perfusion) in alcohol, tobacco and stimulant dependence; only one arterial spin labeling paper in opiate-dependent individuals demonstrated frontal and parietal perfusion deficits. Additional research on regional brain perfusion in opiate dependence and its relationship to cognition and self-regulation (impulsivity, risk taking and decision making) may inform treatment approaches for opiate-dependent individuals...
June 19, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28605471/berlin-grading-system-can-stratify-the-onset-and-predict-perioperative-complications-in-adult-moyamoya-disease
#14
Daina Kashiwazaki, Naoki Akioka, Naoya Kuwayama, Kiyohiro Houkin, Marcus Czabanka, Peter Vajkoczy, Satoshi Kuroda
BACKGROUND: The grading system for moyamoya disease is not established. OBJECTIVE: To assess the usefulness of a recently proposed grading system for stratifying the clinical severity and predicting postoperative morbidity in adult moyamoya disease. METHODS: We investigated 176 hemispheres from 89 adult patients who were diagnosed with moyamoya disease in Japan. Their data were analyzed using the Berlin grading system with minor modifications...
June 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28600750/intra-operative-hemorrhage-due-to-hyperperfusion-during-direct-revascularization-surgery-in-an-adult-patient-with-moyamoya-disease-a-case-report
#15
Hiroki Uchida, Hidenori Endo, Miki Fujimura, Toshiki Endo, Kuniyasu Niizuma, Teiji Tominaga
Hemorrhagic complication is one of the notable surgical complications of the revascularization surgery for moyamoya disease (MMD). Cerebral hyperperfusion (CHP) has been considered as the underlying cause of this complication. It mostly occurs several days after surgery, but the intra-operative hemorrhage immediately after bypass has not been reported previously. A 21-year-old woman presented right thalamic hemorrhage and was diagnosed as having MMD by cerebral angiography. In light of the location of the hemorrhage at the vascular territory of posterior circulation and the manifestation of transient ischemic attack during the follow-up period, she underwent revascularization surgery to prevent future ischemic attack and rebleeding...
June 9, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28592064/-clinical-analysis-on-monitoring-and-comprehensive-treatment-after-carotid-endarterectomy
#16
X Y Wang, Z H Sun, L Liu, C Wu, Z Ji
Objective: To discuss the therapeutic effect of management of carotid endarterectomy in care unit. Methods: A total of 315 patients with carotid atherosclerotic stenosis were enrolled. All of the patients were taken into care unit under tracheal intubation anesthesia after carotid endarterectomy. Then the patients were managed with a breathing machine, continuous sedation, strict monitoring of hemodynamics and pupil change, strict control of heart rate and blood pressure, atomization inhalation therapy, treatment of anticoagulation and antiplatelet therapy and classification management of airway...
May 30, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28589655/cannulation-related-complications-on-veno-arterial-extracorporeal-membrane-oxygenation-prevalence-and-effect-on-mortality
#17
Joshua K Wong, Amber L Melvin, Devang J Joshi, Candice Y Lee, William J Archibald, Ron E Angona, Vakhtang Tchantchaleishvili, Howard T Massey, George L Hicks, Peter A Knight
Cannulation-related complications are a known source of morbidity in patients supported on veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Despite its prevalence, little is known regarding the outcomes of patients who suffer such complications. This is a single institution review of cannulation-related complications and its effect on mortality in patients supported on VA-ECMO from January 2010-2015 using three cannulation strategies: axillary, femoral, and central. Complications were defined as advanced if they required major interventions (fasciotomy, amputation, site conversion)...
June 7, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28582473/connectivity-in-ictal-single-photon-emission-computed-tomography-perfusion-a-cortico-cortical-evoked-potential-study
#18
Simon Tousseyn, Balu Krishnan, Zhong I Wang, Sattawut Wongwiangjunt, Chetan S Nayak, John C Mosher, Guiyun Wu, Wim Van Paesschen, Richard M Leahy, Jorge A Gonzalez-Martinez, Juan Bulacio, Imad M Najm, Andreas V Alexopoulos, Dileep R Nair
Subtraction ictal and interictal single photon emission computed tomography can demonstrate complex ictal perfusion patterns. Regions with ictal hyperperfusion are suggested to reflect seizure onset and propagation pathways. The significance of ictal hypoperfusion is not well understood. The aim of this study was to verify whether ictal perfusion changes, both hyper- and hypoperfusion, correspond to electrically connected brain networks. A total of 36 subtraction ictal and interictal perfusion studies were analysed in 31 consecutive medically refractory focal epilepsy patients, evaluated by stereo-electroencephalography that demonstrated a single focal onset...
July 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28573062/regional-cerebral-blood-flow-in-mild-cognitive-impairment-and-alzheimer-s-disease-measured-with-arterial-spin-labeling-magnetic-resonance-imaging
#19
REVIEW
Alba Sierra-Marcos
Alzheimer's disease (AD) depicts dynamic changes in regional brain function from early stages of the disease. Arterial spin labeling- (ASL-) based MRI methods have been applied for detecting regional cerebral blood flow (rCBF) perfusion changes in patients with AD and mild cognitive impairment (MCI). Nevertheless, the results obtained from ASL studies in AD and MCI are still controversial, since rCBF maps may show both hypoperfusion or hyperperfusion areas in brain structures involved in different cognitive functions...
2017: International Journal of Alzheimer's Disease
https://www.readbyqxmd.com/read/28573058/uncommon-etiology-for-seizure-cerebral-hyperperfusion-syndrome
#20
Mohankumar Kurukumbi, Ahn Truong, Naghemeh Pirsaharkhiz
Cerebral hyperperfusion syndrome (CHS) is a rare life-threatening complication of carotid endarterectomy (CEA) and carotid artery stenting (CAS) for carotid artery stenosis. The incidence varies between 0 and 3%, depending on the severity of the stenosis, perioperative hypertension, and contralateral carotid stenosis. This case report reports a 53-year-old female patient presenting with decreased alertness and multiple tonic-clonic seizures, in the background of bilateral CEA. She was found to have bilateral carotid stenosis...
2017: Case Reports in Neurological Medicine
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